LOCUS       DAVLGK010000001       118226 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLGK010000001 DAVLGK010000000
VERSION     DAVLGK010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 118226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.001"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            144..443
                     /locus_tag="VXE01_000001"
     CDS             144..443
                     /locus_tag="VXE01_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0749010.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSVVSKWDSHSDKGSAPAGKTSEAWIWTKFGEQVSFYYDYD"
     gene            514..2535
                     /locus_tag="VXE01_000002"
     CDS             514..2535
                     /locus_tag="VXE01_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0749011.1"
                     /translation="MKKLFILLSTFFLSFFFAWIIVLRAPQYLYASYDSVTLLRVKKE
                     AQEPTREVFEQELEKFVNSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKQFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKAIADRKTPPYSLAFRMLLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWHDRVDYYQISFGL
                     GDRVNDTENQNKWYEFSKEAVEKEQALFVKENLIHFANPQGKNENGETLDTYSPDANV
                     LYVSPSYLDKENVAVNDETRQKLAHLQKGEFGLLLPESLRSQEAELKKVFEERLNYYG
                     KSSEDKDAPLEYEMRAIVSYLPTGQKRFVYNNGESPVSIQYLTDPILVVFTPTSTGDS
                     FISKYVWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASFFILSSRDLVIGLLTLFVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            2537..3178
                     /locus_tag="VXE01_000003"
     CDS             2537..3178
                     /locus_tag="VXE01_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749012.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKSSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            3282..4634
                     /locus_tag="VXE01_000004"
     CDS             3282..4634
                     /locus_tag="VXE01_000004"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV0749013.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDIPGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            4638..5696
                     /locus_tag="VXE01_000005"
     CDS             4638..5696
                     /locus_tag="VXE01_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV0749014.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            5706..6926
                     /gene="divIB"
                     /locus_tag="VXE01_000006"
     CDS             5706..6926
                     /gene="divIB"
                     /locus_tag="VXE01_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV0749015.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKRLEEEQKKQEE
                     ESNRNQTNQRSSRR"
     gene            7159..7860
                     /gene="pyrF"
                     /locus_tag="VXE01_000007"
     CDS             7159..7860
                     /gene="pyrF"
                     /locus_tag="VXE01_000007"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV0749016.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSVMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            7894..8526
                     /locus_tag="VXE01_000008"
     CDS             7894..8526
                     /locus_tag="VXE01_000008"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV0749017.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            8706..9109
                     /locus_tag="VXE01_000009"
                     /pseudo
     CDS             8706..9109
                     /locus_tag="VXE01_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9205..9969
                     /locus_tag="VXE01_000010"
     CDS             9205..9969
                     /locus_tag="VXE01_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749018.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            9969..10721
                     /locus_tag="VXE01_000011"
     CDS             9969..10721
                     /locus_tag="VXE01_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749019.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTAILFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLALLSIIIPLTVFSVHRNWRRV"
     gene            10731..11429
                     /locus_tag="VXE01_000012"
     CDS             10731..11429
                     /locus_tag="VXE01_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749020.1"
                     /translation="MGKLSSHIWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            11426..12073
                     /locus_tag="VXE01_000013"
     CDS             11426..12073
                     /locus_tag="VXE01_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749021.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(12153..13018)
                     /locus_tag="VXE01_000014"
                     /pseudo
     CDS             complement(12153..13018)
                     /locus_tag="VXE01_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(13030..13794)
                     /locus_tag="VXE01_000015"
                     /pseudo
     CDS             complement(13030..13794)
                     /locus_tag="VXE01_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(13795..14082)
                     /locus_tag="VXE01_000016"
     CDS             complement(13795..14082)
                     /locus_tag="VXE01_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0749022.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            complement(14092..14472)
                     /locus_tag="VXE01_000017"
     CDS             complement(14092..14472)
                     /locus_tag="VXE01_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV0749023.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            complement(14432..15112)
                     /locus_tag="VXE01_000018"
     CDS             complement(14432..15112)
                     /locus_tag="VXE01_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0749024.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
     gene            15327..15473
                     /locus_tag="VXE01_000019"
     CDS             15327..15473
                     /locus_tag="VXE01_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV0749025.1"
                     /translation="MSYKTSNAEGHVDFINTYDLETMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            15601..17091
                     /gene="lysS"
                     /locus_tag="VXE01_000020"
     CDS             15601..17091
                     /gene="lysS"
                     /locus_tag="VXE01_000020"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV0749026.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINKPFKRVHMVDAIKEITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            17716..18852
                     /gene="lctO"
                     /locus_tag="VXE01_000021"
     CDS             17716..18852
                     /gene="lctO"
                     /locus_tag="VXE01_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV0749027.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      19104..19192
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            19407..20075
                     /locus_tag="VXE01_000022"
     CDS             19407..20075
                     /locus_tag="VXE01_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV0749028.1"
                     /translation="METQNYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(20180..20266)
                     /locus_tag="VXE01_000023"
                     /pseudo
     CDS             complement(20180..20266)
                     /locus_tag="VXE01_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            20357..21139
                     /gene="thiM"
                     /locus_tag="VXE01_000024"
     CDS             20357..21139
                     /gene="thiM"
                     /locus_tag="VXE01_000024"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0749029.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            21141..21770
                     /locus_tag="VXE01_000025"
     CDS             21141..21770
                     /locus_tag="VXE01_000025"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0749030.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVVIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      21979..22067
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22329..22889
                     /locus_tag="VXE01_000026"
     CDS             22329..22889
                     /locus_tag="VXE01_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0749031.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            22890..24275
                     /locus_tag="VXE01_000027"
     CDS             22890..24275
                     /locus_tag="VXE01_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749032.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQAI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            24277..24927
                     /locus_tag="VXE01_000028"
     CDS             24277..24927
                     /locus_tag="VXE01_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV0749033.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLLVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            24938..25630
                     /gene="tenA"
                     /locus_tag="VXE01_000029"
     CDS             24938..25630
                     /gene="tenA"
                     /locus_tag="VXE01_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV0749034.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            25635..26159
                     /gene="thiW"
                     /locus_tag="VXE01_000030"
     CDS             25635..26159
                     /gene="thiW"
                     /locus_tag="VXE01_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV0749035.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            26159..26962
                     /locus_tag="VXE01_000031"
     CDS             26159..26962
                     /locus_tag="VXE01_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0749036.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     SREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSKGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEAYE"
     gene            26955..27587
                     /locus_tag="VXE01_000032"
     CDS             26955..27587
                     /locus_tag="VXE01_000032"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0749037.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(27796..28587)
                     /gene="thiD"
                     /locus_tag="VXE01_000033"
     CDS             complement(27796..28587)
                     /gene="thiD"
                     /locus_tag="VXE01_000033"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0749038.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIHPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(28671..28769)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            28953..29348
                     /locus_tag="VXE01_000034"
     CDS             28953..29348
                     /locus_tag="VXE01_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV0749039.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            29359..29730
                     /locus_tag="VXE01_000035"
     CDS             29359..29730
                     /locus_tag="VXE01_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV0749040.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            29740..31983
                     /locus_tag="VXE01_000036"
     CDS             29740..31983
                     /locus_tag="VXE01_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0749041.1"
                     /translation="MTEIVKANLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEAIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALNGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAINQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            32190..33965
                     /gene="spxB"
                     /locus_tag="VXE01_000037"
     CDS             32190..33965
                     /gene="spxB"
                     /locus_tag="VXE01_000037"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV0749042.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            34076..34423
                     /locus_tag="VXE01_000038"
     CDS             34076..34423
                     /locus_tag="VXE01_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0749043.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(34540..34781)
                     /locus_tag="VXE01_000039"
                     /pseudo
     CDS             complement(34540..34781)
                     /locus_tag="VXE01_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            34952..35233
                     /locus_tag="VXE01_000040"
     CDS             34952..35233
                     /locus_tag="VXE01_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV0749044.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            35365..36309
                     /gene="manA"
                     /locus_tag="VXE01_000041"
     CDS             35365..36309
                     /gene="manA"
                     /locus_tag="VXE01_000041"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV0749045.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDTLLTKVPVKAG
                     DFFYVPSGTMHAIGTGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADNLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLFSILAGQGQL
                     TVDGKNYPIQKGSHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(36349..37266)
                     /locus_tag="VXE01_000042"
                     /pseudo
     CDS             complement(36349..37266)
                     /locus_tag="VXE01_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520377.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            37305..38109
                     /locus_tag="VXE01_000043"
     CDS             join(37305..37673,37675..38109)
                     /locus_tag="VXE01_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0749046.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFKEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLLRRSQWVEVTLVQSGFTVSR
                     TPLSSEDTVMIDATEVKINRPKKQLANDSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     SHDMKLFKMSRRNIEQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKAYNHA
                     LSKERSKVENIFAKVKTFKIFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            complement(38106..38351)
                     /locus_tag="VXE01_000044"
     CDS             complement(38106..38351)
                     /locus_tag="VXE01_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV0749047.1"
                     /translation="MEQSPQKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFLQN"
     gene            complement(38366..39538)
                     /locus_tag="VXE01_000045"
     CDS             complement(38366..39538)
                     /locus_tag="VXE01_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0749048.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGANPI"
     gene            complement(39597..40442)
                     /locus_tag="VXE01_000046"
     CDS             complement(39597..40442)
                     /locus_tag="VXE01_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0749049.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            40567..41124
                     /locus_tag="VXE01_000047"
     CDS             40567..41124
                     /locus_tag="VXE01_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0749050.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            41143..41610
                     /locus_tag="VXE01_000048"
     CDS             41143..41610
                     /locus_tag="VXE01_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV0749051.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            41699..42328
                     /gene="upp"
                     /locus_tag="VXE01_000049"
     CDS             41699..42328
                     /gene="upp"
                     /locus_tag="VXE01_000049"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV0749052.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            42502..43092
                     /gene="clpP"
                     /locus_tag="VXE01_000050"
     CDS             42502..43092
                     /gene="clpP"
                     /locus_tag="VXE01_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV0749053.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            43171..43419
                     /locus_tag="VXE01_000051"
     CDS             43171..43419
                     /locus_tag="VXE01_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV0749054.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            43520..44680
                     /locus_tag="VXE01_000052"
     CDS             43520..44680
                     /locus_tag="VXE01_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0749055.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            44948..45817
                     /locus_tag="VXE01_000053"
     CDS             44948..45817
                     /locus_tag="VXE01_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0749056.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            45821..46777
                     /locus_tag="VXE01_000054"
     CDS             45821..46777
                     /locus_tag="VXE01_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0749057.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            46777..47541
                     /locus_tag="VXE01_000055"
     CDS             46777..47541
                     /locus_tag="VXE01_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749058.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            47541..48251
                     /locus_tag="VXE01_000056"
     CDS             47541..48251
                     /locus_tag="VXE01_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749059.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            48559..49215
                     /locus_tag="VXE01_000057"
     CDS             48559..49215
                     /locus_tag="VXE01_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0749060.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            49323..50418
                     /gene="prfB"
                     /locus_tag="VXE01_000058"
     CDS             join(49323..49394,49396..50418)
                     /gene="prfB"
                     /locus_tag="VXE01_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV0749061.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            50436..51128
                     /gene="ftsE"
                     /locus_tag="VXE01_000059"
     CDS             50436..51128
                     /gene="ftsE"
                     /locus_tag="VXE01_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV0749062.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            51121..52047
                     /locus_tag="VXE01_000060"
     CDS             51121..52047
                     /locus_tag="VXE01_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0749063.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            52333..54513
                     /locus_tag="VXE01_000061"
     CDS             52333..54513
                     /locus_tag="VXE01_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0749064.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVTAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            54565..55380
                     /locus_tag="VXE01_000062"
     CDS             54565..55380
                     /locus_tag="VXE01_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0749065.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAVLNWK"
     gene            55585..57237
                     /locus_tag="VXE01_000063"
     CDS             55585..57237
                     /locus_tag="VXE01_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000465985.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0749066.1"
                     /translation="MFFQDRKIKYSIRKLSVATVSLAIGFLFAPAALGVAQVAQADEL
                     STTEQVENKAENQVSVVSFATEQEESETTYVDTTNKVTWTFAGYDKEKIVVGKGRQTF
                     LGSWVPTPNPEYVFKSSKAGVPLPQSILGMLPKDEASYKVGDTIVAKQPAVESVVEEE
                     KDYVWTFKGYDQKNATYNGKRVTFTGIWEVTPRPHHVSYTFVSVTSGVDLPKFIQKKA
                     PKDGSTYFNRTRVFAEEPTTKTYIDSVNDGTWTFKGYDAASAVVNKANVEFVGKWEFK
                     ANPTNAETYTPQVTEETIKVGQTPDLTDNVTNLPNLPAGTKVVDITPAGQIDTTKPGT
                     YTGKVRVDYPDGSSTEVSVSVNVLPAPETQTYKVTYRFESATADNNLPAEVLSLLPQS
                     GTYTTSSSVAIAFVPEAPMPVEVAVANGTWTFLGYQEVEEGSNLTFVGKWVFEAKQDP
                     SPQPQPAPTPQPAPQPNPVPPVNPGGEQGTDNNQADRHQSEQPRKPEENPPAQGPAGE
                     KEKQATLPNAGSTAPLSLTGLVTSSLLAGLAVLLLGRKRKDD"
     gene            57617..58960
                     /locus_tag="VXE01_000064"
     CDS             57617..58960
                     /locus_tag="VXE01_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0749067.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            59337..60527
                     /locus_tag="VXE01_000065"
     CDS             59337..60527
                     /locus_tag="VXE01_000065"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV0749068.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            61080..62015
                     /locus_tag="VXE01_000066"
     CDS             61080..62015
                     /locus_tag="VXE01_000066"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV0749069.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            62049..63086
                     /locus_tag="VXE01_000067"
     CDS             62049..63086
                     /locus_tag="VXE01_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0749070.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            63227..63832
                     /locus_tag="VXE01_000068"
     CDS             63227..63832
                     /locus_tag="VXE01_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV0749071.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            63989..64519
                     /locus_tag="VXE01_000069"
     CDS             63989..64519
                     /locus_tag="VXE01_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV0749072.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            64540..65625
                     /gene="rlmN"
                     /locus_tag="VXE01_000070"
     CDS             64540..65625
                     /gene="rlmN"
                     /locus_tag="VXE01_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV0749073.1"
                     /translation="MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVNHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKLNRAFPIEKLFAAIEYYIETTNRGVTFEYIMLNEVNDGVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            65625..66107
                     /locus_tag="VXE01_000071"
     CDS             65625..66107
                     /locus_tag="VXE01_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0749074.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            66109..67650
                     /locus_tag="VXE01_000072"
     CDS             66109..67650
                     /locus_tag="VXE01_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0749075.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(67707..68510)
                     /locus_tag="VXE01_000073"
     CDS             complement(67707..68510)
                     /locus_tag="VXE01_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV0749076.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(68594..68806)
                     /locus_tag="VXE01_000074"
     CDS             complement(68594..68806)
                     /locus_tag="VXE01_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749077.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            complement(69285..69494)
                     /locus_tag="VXE01_000075"
     CDS             complement(69285..69494)
                     /locus_tag="VXE01_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749078.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            69664..69936
                     /gene="rpsP"
                     /locus_tag="VXE01_000076"
     CDS             69664..69936
                     /gene="rpsP"
                     /locus_tag="VXE01_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV0749079.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            69956..70195
                     /locus_tag="VXE01_000077"
     CDS             69956..70195
                     /locus_tag="VXE01_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV0749080.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            70772..71560
                     /locus_tag="VXE01_000078"
     CDS             70772..71560
                     /locus_tag="VXE01_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0749081.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEALEELGISEYILCVHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNRHYLQWSESEKIAAIIRELSE"
     gene            71591..72109
                     /gene="rimM"
                     /locus_tag="VXE01_000079"
     CDS             71591..72109
                     /gene="rimM"
                     /locus_tag="VXE01_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV0749082.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            72099..72818
                     /gene="trmD"
                     /locus_tag="VXE01_000080"
     CDS             72099..72818
                     /gene="trmD"
                     /locus_tag="VXE01_000080"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV0749083.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            72830..73168
                     /locus_tag="VXE01_000081"
     CDS             72830..73168
                     /locus_tag="VXE01_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749084.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(73198..73518)
                     /locus_tag="VXE01_000082"
     CDS             complement(73198..73518)
                     /locus_tag="VXE01_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749085.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            73616..73831
                     /locus_tag="VXE01_000083"
     CDS             73616..73831
                     /locus_tag="VXE01_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV0749086.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(73900..73986)
                     /locus_tag="VXE01_000084"
                     /pseudo
     CDS             complement(73900..73986)
                     /locus_tag="VXE01_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(74037..74573)
                     /locus_tag="VXE01_000085"
     CDS             complement(74037..74573)
                     /locus_tag="VXE01_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV0749087.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(74770..76116)
                     /gene="gor"
                     /locus_tag="VXE01_000086"
     CDS             complement(74770..76116)
                     /gene="gor"
                     /locus_tag="VXE01_000086"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV0749088.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAQAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNRESYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            76381..77580
                     /locus_tag="VXE01_000087"
     CDS             76381..77580
                     /locus_tag="VXE01_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV0749089.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            77564..78265
                     /locus_tag="VXE01_000088"
     CDS             77564..78265
                     /locus_tag="VXE01_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749090.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            78267..79526
                     /locus_tag="VXE01_000089"
     CDS             78267..79526
                     /locus_tag="VXE01_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0749091.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYEFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            79650..81647
                     /gene="metG"
                     /locus_tag="VXE01_000090"
     CDS             79650..81647
                     /gene="metG"
                     /locus_tag="VXE01_000090"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0749092.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            81691..81771
                     /locus_tag="VXE01_000091"
                     /pseudo
     CDS             81691..81771
                     /locus_tag="VXE01_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            81978..82298
                     /locus_tag="VXE01_000092"
     CDS             81978..82298
                     /locus_tag="VXE01_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0749093.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            82302..83117
                     /locus_tag="VXE01_000093"
     CDS             82302..83117
                     /locus_tag="VXE01_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749094.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVILGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKETVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            83192..84118
                     /locus_tag="VXE01_000094"
     CDS             83192..84118
                     /locus_tag="VXE01_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV0749095.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            84184..84450
                     /locus_tag="VXE01_000095"
     CDS             84184..84450
                     /locus_tag="VXE01_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV0749096.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            84443..85141
                     /locus_tag="VXE01_000096"
     CDS             84443..85141
                     /locus_tag="VXE01_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV0749097.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPSGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            85152..85652
                     /locus_tag="VXE01_000097"
     CDS             85152..85652
                     /locus_tag="VXE01_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0749098.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            85630..86499
                     /locus_tag="VXE01_000098"
     CDS             85630..86499
                     /locus_tag="VXE01_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV0749099.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTTPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            86474..86914
                     /locus_tag="VXE01_000099"
     CDS             86474..86914
                     /locus_tag="VXE01_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV0749100.1"
                     /translation="MIPQEMWNKYKQINPSIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVKPFNRVSADHAYKEGE
                     GNKTLVYWRQVHEDFFRDCLGEAGLTFTPESKVVLEEFRKVYPL"
     gene            87037..89583
                     /locus_tag="VXE01_000100"
     CDS             87037..89583
                     /locus_tag="VXE01_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV0749101.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISAFERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            89691..90365
                     /gene="ciaR"
                     /locus_tag="VXE01_000101"
     CDS             89691..90365
                     /gene="ciaR"
                     /locus_tag="VXE01_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV0749102.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            90355..91689
                     /gene="ciaH"
                     /locus_tag="VXE01_000102"
     CDS             90355..91689
                     /gene="ciaH"
                     /locus_tag="VXE01_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV0749103.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(91723..92010)
                     /locus_tag="VXE01_000103"
     CDS             complement(91723..92010)
                     /locus_tag="VXE01_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV0749104.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            92150..93079
                     /locus_tag="VXE01_000104"
     CDS             92150..93079
                     /locus_tag="VXE01_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0749105.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQVFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            93279..95729
                     /locus_tag="VXE01_000105"
     CDS             93279..95729
                     /locus_tag="VXE01_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV0749106.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVFLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            95766..96989
                     /locus_tag="VXE01_000106"
     CDS             95766..96989
                     /locus_tag="VXE01_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0749107.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            97000..97554
                     /locus_tag="VXE01_000107"
     CDS             97000..97554
                     /locus_tag="VXE01_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV0749108.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            97639..98202
                     /locus_tag="VXE01_000108"
     CDS             97639..98202
                     /locus_tag="VXE01_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0749109.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            98217..100163
                     /gene="gyrB"
                     /locus_tag="VXE01_000109"
     CDS             98217..100163
                     /gene="gyrB"
                     /locus_tag="VXE01_000109"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV0749110.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGYTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            100245..101972
                     /gene="ezrA"
                     /locus_tag="VXE01_000110"
     CDS             100245..101972
                     /gene="ezrA"
                     /locus_tag="VXE01_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV0749111.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(102701..103024)
                     /gene="tnpB"
                     /locus_tag="VXE01_000111"
                     /pseudo
     CDS             complement(102701..103024)
                     /gene="tnpB"
                     /locus_tag="VXE01_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(103284..103583)
                     /locus_tag="VXE01_000112"
     CDS             complement(103284..103583)
                     /locus_tag="VXE01_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV0749112.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(103748..104203)
                     /locus_tag="VXE01_000113"
     CDS             complement(103748..104203)
                     /locus_tag="VXE01_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0749113.1"
                     /translation="MQWQTQLSEKKANTDYIARYGVYAVIPNPEQKQIVLVQEPNGAW
                     FLPCGEIEAGENHQEALKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYSNPAYFY
                     EATPFKEVQKPLENFNHIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            104280..105230
                     /locus_tag="VXE01_000114"
                     /pseudo
     CDS             104280..105230
                     /locus_tag="VXE01_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(105437..107695)
                     /locus_tag="VXE01_000115"
     CDS             complement(105437..107695)
                     /locus_tag="VXE01_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0749114.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLKEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KKKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(107924..108154)
                     /locus_tag="VXE01_000116"
     CDS             complement(107924..108154)
                     /locus_tag="VXE01_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV0749115.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            108344..109027
                     /locus_tag="VXE01_000117"
     CDS             108344..109027
                     /locus_tag="VXE01_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0749116.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            109027..109761
                     /locus_tag="VXE01_000118"
     CDS             109027..109761
                     /locus_tag="VXE01_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0749117.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            109915..110772
                     /locus_tag="VXE01_000119"
     CDS             109915..110772
                     /locus_tag="VXE01_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV0749118.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            110909..111730
                     /locus_tag="VXE01_000120"
     CDS             110909..111730
                     /locus_tag="VXE01_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEV0749119.1"
                     /translation="MILKIYNREYSLQWDGIYYLALIDYPNIQEWELEKIAKFIAYEK
                     LHKRQTSIECADSCLKKEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHT
                     TTIDAAISIFKTGQLLSAVKAFRRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGY
                     RLAMERLLGRAPSEKELQDKFIPGVSFHFIYTDLIKVTGYIFDGYHVAKIKDMLNLFS
                     ELYICIIPTHNKSQFENIIPTKIQDRVHYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            111744..112583
                     /locus_tag="VXE01_000121"
     CDS             111744..112583
                     /locus_tag="VXE01_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV0749120.1"
                     /translation="MKVIDQALLEKVIIERSRTSHKGDYGRLLFLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDAFGEDLVKQVFAGLRQNQILIVDGGALTILARTSLSFSSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASALTSFPQGTILVEKGSATRIWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFAGQFKQASLYERVAVATHLHSAIAQELAQEQYVVLPTEISNCLPKVMK
                     RYV"
     gene            112881..113564
                     /gene="rpiA"
                     /locus_tag="VXE01_000122"
     CDS             112881..113564
                     /gene="rpiA"
                     /locus_tag="VXE01_000122"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV0749121.1"
                     /translation="MENLKKMAGIKAAEFVKDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQIIAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHIVGVVEHGLFNQMVDKVIVAGRDGV
                     QILTSKKGK"
     gene            113578..114789
                     /locus_tag="VXE01_000123"
     CDS             113578..114789
                     /locus_tag="VXE01_000123"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV0749122.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVPAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFAPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGVIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            114791..115351
                     /locus_tag="VXE01_000124"
     CDS             114791..115351
                     /locus_tag="VXE01_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV0749123.1"
                     /translation="MTCYALLVRGINVGGKNKVVMAELRQELTELGIEKVESYINSGN
                     VFFTSTVPKARLIEKLETFFAVHYPFIQSFSLLSQEDYEAEVENLPAWWNEDLARKDV
                     LFYTELLDVEQVITTVESLELKDEVVHFGKLGIFWGKFSEESYPKTAYHKYLLKMPFY
                     CHITIRNAKTFDKIGQMLKNNKGDTQ"
     gene            115348..116157
                     /locus_tag="VXE01_000125"
     CDS             115348..116157
                     /locus_tag="VXE01_000125"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0749124.1"
                     /translation="MTFLNKIHETATFLKEKGIQTPEFGLILGSGLGELAEEIENPVV
                     VDYADIPNWGRSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGYGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSKAYTP
                     EYRATAHQVAKKLGIKLDEGVYIGVTGPTYETPAEIRAYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            116464..116550
                     /locus_tag="VXE01_000126"
     CDS             116464..116550
                     /locus_tag="VXE01_000126"
                     /inference="COORDINATES: protein motif:HMM:TIGR01168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0749125.1"
                     /translation="MKIGQRIMRFGIKKLNIGVVSVAVGFDF"
     gene            116601..117005
                     /locus_tag="VXE01_000127"
                     /pseudo
     CDS             116601..117005
                     /locus_tag="VXE01_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            117018..117592
                     /locus_tag="VXE01_000128"
                     /pseudo
     CDS             117018..117592
                     /locus_tag="VXE01_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            117617..118129
                     /locus_tag="VXE01_000129"
     CDS             117617..118129
                     /locus_tag="VXE01_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV0749126.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNFPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
BASE COUNT        35798 a        21385 c        25768 g        35275 t
ORIGIN      
        1 taaaaaattc gattttttcc ttgacaacaa ataataaaaa tgctattctt attatataag
       61 aaatcggttt caaaaaagag agaggaggat ttattttgtt gcattgttgc tcagggtgtg
      121 ctttttttga aaggaaaaat aaaatgaaaa cgaaaaaaca tagattactt gctctagctc
      181 ttatttcaag ctttacatta ttgggagctg catcagctgc tgtacaatat ccagatggag
      241 gagtatggac atatggagaa ggttcaggag gtggttgggc tttttcaaat tactatcatg
      301 gtaaaaaata tcattattct tctgttgtaa gtaaatggga tagtcattca gataaaggat
      361 cagcacctgc agggaaaact tcagaggctt ggatttggac taaatttggg gaacaagtat
      421 cattttacta tgactatgac taatatttag ttttcttaga taattcccct tgtaagaaat
      481 tacaggggga attttgttta caaggagtct actatgaaga aactattcat attactatca
      541 actttttttc tcagcttctt ctttgcttgg attattgtct tacgtgcgcc acaatattta
      601 tatgcaagct atgattccgt tactttactt cgtgtcaaaa aagaggctca ggaaccgact
      661 cgtgaggtat ttgaacagga attggagaag tttgtaaact cagaacagag tttaatagct
      721 aggagaattg tagaaccgag taaggatggg acgactcact ttacttatgc aacttatggt
      781 cagggaacat taccaaaaca attccaagaa gctagccaag aaagtcgtga acgtagtgat
      841 ccgctaaata gttatctcct tttatcaggc tccttgacaa aagaaaagct agctgataaa
      901 ttaggagatt taggttataa agcaattgct gaccgaaaga cacctcccta ttctcttgct
      961 tttcgaatgt tactaaatcc ccttatttta attagtttag caatatttgg cttatctttc
     1021 tttgctttag tgattatcac tcggattaag gaaatgagag cagcaggtat aaaactcttt
     1081 tctggtcaga ctctcttatc cattatgggg cattctttat ctactgatat taagtggctc
     1141 cttctatcag ccctcctttc cttcctaggt gggggagtcg ttctttttag tcaaggtttg
     1201 ttttatccta tcttgttagc cacctatggt tttgggatta gtttctatct gttgttttta
     1261 ttggcgattt caattttact aatgctcctt tatctaatga gtttgagtta caaagcatta
     1321 gttcccgtta ttaagggaag attacccctt aaacgcctga tgattttaac cctattgtgt
     1381 cagttggttg ctgtctttac agtgggatac gctgttaaga caggtttgac gtcttaccaa
     1441 cgattgaaag aacttgaaat ttcaaaacaa gcatggcatg acagagtaga ctattatcaa
     1501 atttcttttg gcttaggtga cagagtaaat gatacagaaa atcagaataa gtggtatgaa
     1561 ttttccaaag aagcagttga aaaagaacag gctctatttg taaaagagaa tctcattcat
     1621 tttgcaaatc ctcaaggaaa aaatgaaaac ggggaaacac tggataccta tagtccagat
     1681 gctaatgttc tctatgtgag tccaagttat ttagacaagg aaaatgtggc tgtaaatgat
     1741 gagactagac agaaactagc tcatcttcaa aaaggggaat ttggactctt attaccagaa
     1801 tctcttcgtt cacaggaagc agaacttaag aaagtttttg aagaacgttt gaactattac
     1861 ggaaaatcaa gcgaggataa agacgctcct ttagagtatg aaatgagagc gattgttagc
     1921 tatcttccaa caggacaaaa acgctttgtt tataataacg gtgaaagtcc agtatctatt
     1981 cagtacttaa ccgatccgat tttagttgta tttactccaa catctacagg tgatagtttc
     2041 atttcaaaat atgtttggtc tatcaatgct ggaaaacaac tctttatcaa aggatatgag
     2101 agtgggctag aactcttaaa gaaagctgga atttatgagc aagtatccta tcttaaagaa
     2161 ggaagaagtg tttatctaac tcgttataat gaagttcaaa ctgaaacagc aactttaatc
     2221 ttaggagcta ttgttgggat agccagttcc ttattactct tttattctgt caatcttcta
     2281 tatttcgagc aattccgccg agatatcttg attaaacgaa tttcaggttt acgatttttt
     2341 gaaacacatg ctcagtatat ggttagccaa tttgccagtt ttgtatttgg tgctagtttc
     2401 tttattttaa gcagtcgaga cttggtgatt ggcttgctca ctttattcgt ctttctagct
     2461 agtgcagttc tgacgcttta ccgtcaagca cagaaagaat ctcgtgtttc tatgacaatt
     2521 atgaaaggaa aataggatga ttgaactaaa gaatatatct aaaaaatttg gaagccgtca
     2581 gctattttca gatacaaatc ttcattttga aggtgggaaa atttatgcct taatcggtac
     2641 aagtggctgt ggtaagacaa cactcttgaa tatgattgga cgattagagc catatgacaa
     2701 agggcaaatc atctatgatg gcacttctct taaggacatc aagtcttctg ttttctttag
     2761 agattacttg ggatacttat ttcaagattt tggcttaatt gaaagccaaa ccgtcaaaga
     2821 gaatctcaat ctgggtttag ttggtaaaaa gttgaaggaa aaagagaaaa tctctttgat
     2881 gaaacaagct ctaaaccgtg taaacctctc ttatttggat ttgaagcaac ctatatttga
     2941 gttatcagga ggagaagcac aacgtgttgc attagcgaag ataattttaa aggatccgcc
     3001 tttgattctt gcagatgaac caaccgcttc cttagacccc aaaaactctg aggaattact
     3061 ttccatccta gaatctttaa aaaatccgaa tcggaccatt attattgcga cccacaatcc
     3121 tctgatttgg gagcaagtgg atcaggtcat tcgagttacc gatttatcac atagatgata
     3181 tggtaagatt cagttagaag aaagagtcac aaacacactt tgtggctttt ttatttccat
     3241 aaaaatggta aaatagtagg agtagaaatg gagttcgaga catgaaagta atagatcaat
     3301 ttaaaaataa gaaagtcctt gttttaggtt tggccaagtc tggtgaatct gcagctcgtt
     3361 tgttggacaa gctaggtgcc attgtgacag taaatgatgg gaaacctttc gaggacaatc
     3421 cagctgccca aagtttgctg gaagaaggga tcaaggtcat tacaggtggc catcctttgg
     3481 aactcttgga tgaagagttt gcccttatgg tgaaaaatcc aggtatcccc tacaacaatc
     3541 ccatgattga aaaggctttg gccaagggaa ttccagtctt gactgaggtg gaattggctt
     3601 atttgatttc agaagcaccg attattggta tcacaggatc gaacggtaag acaaccacaa
     3661 cgactatgat tggggaagtt ttgactgctg ctgggcaaca tggtctttta tcagggaata
     3721 tcggctatcc agctagtcaa gtggcccaaa ctgcgtcgga caaggacacg cttgttatgg
     3781 aactttcttc tttccaactc atgggtgttc aagaatttca tccagagatt gcggttatta
     3841 ccaacctcat gccaactcat atcgactacc atgggtcatt ttcggaatat gtagcagcca
     3901 agtggaatat ccagaacaag atgacagcag ctgatttcct tgtcttgaac tttaatcaag
     3961 acttggcaaa agacttgact tccaagacag aagccactgt tgtaccattt tcaacacttg
     4021 aaaaggttga tggagcttat ctggaagatg gtcaactcta cttccgtggt gaagtagtca
     4081 tggcagcgaa tgaaatcggt gttccaggta gccacaatgt ggaaaatgcc cttgcgacta
     4141 ttgctgtagc caagcttcgt ggtgtggaca atcaaaccat caaggaaact ctttcagcct
     4201 tcggtggtgt caaacaccgt ctccagtttg tggatgacat caagggtgtt aaattctata
     4261 acgacagtaa atcaactaat atcttggcta ctcaaaaagc cttgtcagga tttgacaaca
     4321 gcaaggtcgt cttgattgca ggtggtttgg accgtggcaa tgagtttgac gaattggtgc
     4381 cagacattcc tggactcaag aagatggtca tcctgggtca atctgcagaa cgtgtcaaac
     4441 gggcagcaga caaggctggt gtcgcttatg tggaggcgac agatattgca gatgcgaccc
     4501 gcaaggccta tgagcttgcg actcaaggag atgtggttct tcttagtcct gccaatgcca
     4561 gctgggatat gtatgctaac tttgaagtac gtggcgacct ctttatcgac acagtagcgg
     4621 agttaaaaga ataaaatatg aaaaaaattg tctttacagg tggggggacg gttggacacg
     4681 ttaccctcaa tcttttgtta atgcccaagt tcatcgaaga tggttgggaa gtccactata
     4741 tcggggacaa gcgtggtatc gaacaccaag aaatccttaa gtcaggtttg gatgtcactt
     4801 tccactccat tgcgactgga aaattgcgtc gctatttctc ttggcaaaat atgctggacg
     4861 tcttcaaagt ttgctgggga atcgtccaat cgctctttat catgttgcga cttcgtccac
     4921 agaccctttt ttcaaagggg ggctttgtct cagtaccgcc tgttatcgct gcgcgtgtgt
     4981 caggagtgcc tgtctttatt cacgaatctg acctgtctat gggcttggcc aataaaatcg
     5041 cctataaatt tgcgactaag atgtattcaa cctttgagca agcttcgagt ttgtctaagg
     5101 ttgagcatgt gggagcagtg accaaggttt cagatcaaaa aaatccagaa ccagatgaat
     5161 tggtggatat tcaaagccac tttaatcata aattgccgac tgtattgttt gttggcggtt
     5221 ctgcaggtgc tcgtgtcttt aaccaattgg tgacagacca taagaaagaa ctaacagagc
     5281 gctacaatat tatcaatcta actggagatt ctagcctgaa tgagttgagc caaaatcttt
     5341 ttcgtgttga ctatgtgacc gatctctatc aacccttgat ggaattggct gatattgttg
     5401 tgacacgagg tggtgccaat acgatttttg agctcttggc gatagcaaaa ttgcatgtca
     5461 ttgtgccgct tggtcgtgaa gctagtcgtg gtgaccagct tgaaaatgca gcttactttg
     5521 taaaaaaagg ctatgcagaa gaccttcaag aaagcgattt gaccttggat agtttggaag
     5581 agaagctttc tcacttacta agtcacaagg aagattacca agctaagatg aaggcttcta
     5641 aggaattgaa atctctagca gatttttatc aattgttgaa aaaagattta tcataaggaa
     5701 agtaaatgtc aaaagataag aaaaatgagg acaaagaaat cctcgaagaa ttgaaagagt
     5761 tatcagaatg gcagaaacga aaccaagaat atctaaaaaa gaaggctgaa gaagaggcgg
     5821 ctctagctga ggagaaggaa aaggaaagac aagctcgaat gggagaagaa tctgagaagt
     5881 cagaggacaa acaggaccag gagagtgaaa cagaccagga agattcagaa tcagctaagg
     5941 aagagtctga agaaaaagta gcatcctcag aggctgacaa agagaaagaa gagaaagaag
     6001 aaccagagtc taaagagaag gaggaacagg ataaaaagct ttctaaaaag gctacaaagg
     6061 aaaaaccagc caaagcaaag attcctggta tccatatctt gcgagcattc acgattttat
     6121 ttccaagtct gcttttattg attgtctctg cctacttgct cagtccttat gcgaccatga
     6181 aagatattcg tgttgaggga acggtgcaaa ctacagctga tgatattcga caggcttcag
     6241 gcattcagga ttcggattat acgattaacc ttctgctaga caaggcaaaa tatgaaaagc
     6301 agattaagtc taactattgg gttgaatcag ctcaacttgt ctatcaattt ccaactaagt
     6361 tcactattaa ggtcaaggaa tatgatattg tggcctacta tatttctggt gaaaatcatt
     6421 atcctattct ttccagtggt cagcttgaga ctagttctgt gagtctgaac agtttaccag
     6481 aaacttattt atcagttctc tttaatgata gtgaacaaat caaggttttt gtctcagaac
     6541 ttgctcaaat tagcccagaa ctcaaggcgg ctatccaaaa ggtggaatta gccccaagca
     6601 aggtgacatc cgatttaatt cgattgacca tgaatgattc ggacgaagtc ttggttcctc
     6661 tatctgaaat gagtaagaaa ctgccatatt atagtaagat taagccacaa ttgtcagaac
     6721 cgagtgtggt cgacatggaa gctggaattt acagttacac tgtggcggat aaattaatta
     6781 tggaggctga ggaaaaagcc aaacaagagg ccaaggaagc cgagaaaaaa caggaagaag
     6841 aacagaaacg tttagaagaa gaacagaaaa aacaagagga agagagcaat cgaaatcaaa
     6901 caaatcagcg ttcatcgcgt cgctaggttt accttttctc ttatagttct ttagtgacca
     6961 tgtttttact tgacaagtgc tagtagaaat aatagaataa tagaaaacct ttaaagcagt
     7021 ccagagaggc agctaaggtt agacggtgaa agggtggaga ctacccattt ttcgtggaac
     7081 cttgctgttg gcaggttcct tttttcgtgg cttctgttgg ccagactctc tcactagtaa
     7141 aggtaaaagg agaaacctat gcgagaacat cgtccaatca ttgctcttga ttttcctagt
     7201 tttgaggcgg tcaaggaatt tttagctctt ttcccagcag aagaaagcct ttatctcaag
     7261 gtagggatgg agctttatta cgcagcgggg cctgagattg tgtcctactt aaaaggtttg
     7321 ggtcatagtg tctttttgga tctcaaactt catgacattc ctaatacagt caagtcagtc
     7381 atgaagatcc tatctcagct tggtgtggat atgaccaatg ttcatgcggc tggtggtgta
     7441 gagatgatga aggctgcgcg tgaaggtctt ggaagtcaag ctaaattgat cgctgtaact
     7501 cagctcacat caacgtcaga agctcagatg caggagtttc aaaatatcca aaccagtctg
     7561 caagagtctg tgattcacta tgccaagaag acagctgaag ctggcttgga tggtgttgtt
     7621 tgctcggctc aggaagtaca agtcatcaag caggctacca atccagattt tatctgtctg
     7681 acaccaggga ttcgtccagc tggtgttgca gttggagatc aaaaacgagt catgacacct
     7741 gctgatgcct atcaaatcgg cagtgactat atcgtagtgg gacgtcccat tacccaagct
     7801 gaggatcctg ttgcagctta tcatgccatc aaggatgaat ggacacagga ctggaattaa
     7861 agaactagat tagaaaaata aaaggagaat accatgacac ttgctaaaga tatcgctagc
     7921 cacctcttga aaatccaagc cgtttacctc aaaccagagg aacccttcac ttgggcatct
     7981 ggtatcaagt caccgattta cactgataat cgtgtgacac tagcctatcc agaaactcgt
     8041 accctaattg aaaatggttt tgtggaagct atcaaagaag cctttcctga agtagaagtg
     8101 attgcaggaa ctgcaacagc agggattcca cacggagcca ttattgctga taagatggac
     8161 ttgccttttg cctacatccg tagcaaacca aaagaccacg gagctggtaa tcaaatcgaa
     8221 ggtcgcgtag ctcaaggtca aaaaatggta gtggttgaag accttatttc aacgggtggt
     8281 tcagttcttg aagctgtagc agcagccaag cgagaaggag cagatgtact tggagttgta
     8341 gcgattttca gctaccaatt gccaaaagca gataagaact ttgcagatgc tggtgttaaa
     8401 cttgtgacgc tttcaaacta tagcgagctt atccatctag cccaagaaga aggttacatc
     8461 acgccagagg gccttgatct tctaaaacgc tttaaagaag accaagaaaa ttggcaagaa
     8521 ggttaggtca gtaagataaa gagagacgag gctaccgagt ctcttttacc attttattta
     8581 aaatatgaca atattttaaa taaaataatt gacaacgctt tcttttattg atataatgaa
     8641 aatgtaatat gtatcaaatt gatcaatcaa ctatcttgtt tatcacttct taagaggacg
     8701 atgtcatgaa aagaagaaaa atatattcct tttttgcgta gttacaattg catctagttt
     8761 gtttctccct acagttttag ctagacagat tggaaattat gatttaacgt tgccgcgttg
     8821 gggttcggat acaactagtg agcttgagaa agaaaacgcc tctgctggaa ttaataatag
     8881 tgacagcact ggtggcggta aaaggttaaa tacctctatt cgtagcgcct atagtgggtc
     8941 agatattacc ccggtatatt cattggggtc tggctctagg attgtcatgt actataatgg
     9001 aggtggtgac aattatattg gttctggtac tagattagct atggcgccac aatttggaaa
     9061 tcatgtaaga attcatactt caggttcttg gagtccagat tcttattaac ttacttgtca
     9121 gagtaagcct taaagatggt tgattgtggg tgtagcatga aaaaagaatg ctacacccta
     9181 tttttattat aaggaggagt aaggatggaa tttttcattt gtaatcttgt acgagtcgtt
     9241 caatcacctc ggttttatat gtctttattt ttgacccttc tttgcatgag tttaggaaat
     9301 tttcttgctt tcaatggtat ttataaaatt gaaggtttat cgattttttt tgccgcttct
     9361 tctattcgag gattttcacc gattagccta gtagctgcac ttatctgtac actgccctat
     9421 tctagtcaga taatagagga tgctgagagt cattttctaa cagcacaatt gtgccgaatt
     9481 tctaaaaaga ggtatctagc tattgtaggt agtactgcaa ttatttcttc ttttctagtc
     9541 ttttttctcc cctatttatt attattagga attaatcttt tagtgactcc ttatcaggaa
     9601 atttatattg gagattatag tggtgcctta aaagaattat ttgattctaa tcagtttctc
     9661 tatagtcttg tgacgactct ctggtatgga gtttggggcg ctgtgttctc tatttttgga
     9721 ctagctagtg ctttgctagt gaagaaaaaa ttaggagcta ttttcatccc agttgcctat
     9781 atgatggttg gtggtatttt atgggctatt ttagggctat cttacttaga acctgtgaca
     9841 acgctagctt tgggatatca gaaagatatc agtctttcct tagttagtgg gcatcttgct
     9901 tttattttat ttgttagttg tttggttgtt tatggtacat tttttctaca ttcagaggac
     9961 tatgtataat gaaacaattt gttcaatttt ataaaaaaga tttcttagca gtattggttt
    10021 attttatatt actgctatcc tgtgttttat ctagtacagt atatttattg cgctgtcgcc
    10081 aatattcaat ccatccaaat gtattagaat ggatcttagt tttacttcaa gatatgacga
    10141 ctggagtata ttgctttccg ttcacatata tattgttctt tttttatttg atgaataact
    10201 attttaatag gttggagtgt cgcattcgtc tgaaatcaat taagcacttt accagtttta
    10261 gtttcaaatt agcagctctt agtacgggga tttggacggc gattttattt ttattgattt
    10321 ttctaattgc atttagtaat ggttttagct tctctttgga gataaaggag gttgattttt
    10381 taagagaatt ttatggcata agtattgcaa acaatgctag tttctttata ggattttttt
    10441 tctcttatat agcatactat ttctttttat ccttacttac tattagcagt ttttcttggt
    10501 ttaaaaaatc aaacatgagc ttagtatttc tgtttacttt tttatttgta gaatccttat
    10561 tctggattta tcagttgaac aatgggataa ttggattatt gccaattttt cagtatatgg
    10621 taaattccaa tccgtatgca ttgatttatt ggcttgcatt actatctatc ataattccat
    10681 tgactgtatt ttctgttcat agaaactgga ggagagtgta aaagttggaa atgggaaagt
    10741 taagtagtca catatggagg ttgaatcaga taatctatac caagtacttt tggggttatg
    10801 ttcttttttg gatattgatt tgtttaggat tatggtattg gttagaagga aatgatagac
    10861 ttgttataga aattttaaaa gggcctaatc tgagtcaaaa ctctttttta gtcttatcta
    10921 tatggttgct tcattggttt attattcata cattttttct agcagttgta tatcgtagaa
    10981 gagcatccga tttctttatg gaagtgattc gattttcttc tattaagctc tggattaggt
    11041 atcagatttg gacctgtttt ctttatggac tcattttaat catggtaaaa gttctagtga
    11101 ttcaatttat gttacagtta gcaaactggg atataggagt tttgtttata gttgattctt
    11161 tgaatgcttg tgtgctatcc ttgctttgct ttatgttata cgcactagga gcgaatgtac
    11221 aaatgaactt tgcttgcgtt agtttctttt tactcatgat tgtgtttggt ggtctatttg
    11281 taggaaatcg aactaattat ctattttata ttttgaatcg agggaatgga gatataggac
    11341 gagatttatt tcttcagttg ctatttttag tctttctttt taaaagcatt ttctatttca
    11401 ctcgtcaaaa gaggaggttt atagaatgaa tgaaataatt acattaaaaa atattgagtt
    11461 gaaattaaaa aaaacatgtg tttttcaaaa ccttaatttt agttgtaaac agggggaaat
    11521 tataggaatt actggtgcga atggctcagg taaaagtgta ttgtttaaat taatagctgg
    11581 tttatatagt ccgtcttatg gagaagtgtt aatcaatggg gaaaatattg ttcctgagag
    11641 aaaaattcca gctaatttgg gagctttgat tgaagaacct ggttttataa attattatag
    11701 tggctttaag aatttacaat atttggcaag catacgagga gtagttggta atcaggaaat
    11761 caatgataca ctgaaaatag ttggtctata tgagcaaaaa gaccagaaag ttaaaactta
    11821 ttcgctaggt atgaggaaaa agctagggat tgctcaagca attatggaga atccctctat
    11881 tcttttacta gatgaaccta tgaatgcctt ggataaatca agtgtagaaa atatgagaac
    11941 attgtttaga aagctctcta gtgaaaaagg gacaacaatt ttgattgcta gtcatagtga
    12001 agaggatatt cgtatcttat gtgataaagt atatgcaata gaagataaag tatgtacact
    12061 gtgttcagat tgaacatctt agatagactc aggatgttat aggtaaaatc ttaaaaaggg
    12121 attggagctt aaaatccagt cccttttaag agttaatggc caccttcaac aaccaggtca
    12181 tctgctttag cagcgtcacc gtaggttggg tgaagtgttt tttcataggc cttgtggaag
    12241 aagttttcct tgcctaattt ttcaatatct ttattgatga agtctagcaa ttcttggttg
    12301 cctttttgaa ctgctgccgc aatggtatcg ggatcaccga gggaagtaat tcctacttca
    12361 aatcctttat tttcaagtgc ccaagctaga acttccgtat tgtcagttga aaaggcatct
    12421 ccacgtccgt caagaagagc ttggtaagag tcactgtatt ggtcgtattt ttggagtttg
    12481 atttctggat gattcttttc aaaataagtc tcagcagtcg ttccttttgt gacaattaag
    12541 gttttacctt caagttgttt gacgtctgta atgagaccag tcttaggtga tacgacaccc
    12601 agagaaactt tcatatatgg aagggcaaaa tcaacttgtt tcttacgttc gtcagttact
    12661 gtaaagttag caagagtaat atctaccttg tttgaaatca agtattccgc acggttggca
    12721 gcatcgactg aaatgtattt aaccttgaca ccaaggtctt gagctagttg gttccctagt
    12781 tcaatatcgt agcgtagcct tggtaagaac catcattgtc aacgtagcca aacggttttt
    12841 tatctccaaa cacggcgatt cgcagttcac cgcttttttt gatttcatcg atagtgcgag
    12901 ctttggcagt tgtttttcca gaggatgaac cagcgtttcc acctgagcta caagcagtga
    12961 taaagataag ggcaaaggca agtgctaaaa cagttaagag tggtttgaat agtttcataa
    13021 gaatctcctt tatagatatg agccgaattg gctaaagtca aagacgttta aaaattcctg
    13081 ggctcgtttg gtttgcggat tggtaaagaa ggcttgagct gttccttctt cagcgatttt
    13141 cccttggtcg aggaagataa tccggtcagt aatggcttgg gcaaactgca tttcgtgggt
    13201 tactaaaatc atggtacggc cttcttgggc caaatcattg ataagttcca gcacctcacg
    13261 caccatttct ggatccagcg aagcagtcac ctcgtcaaaa aggatgattt ctggatgcat
    13321 taggagggca cgggcaattg caacacgttg cttctgtcca ccagataatt gacgggcaaa
    13381 gcaaagctat gttgtttatc cagcaaatcg acacgatcta gtaattgcaa agcttcttcc
    13441 gttacttctt tcttgtccct tccttgagct ttgatagggc ctaggatgag gttttgtaag
    13501 acatccagat ggggaaagag ttcataactt tgaaagacca tgccaatctt ttggcgaact
    13561 aggtgaaaat cttttttatt ttcaacgata gactgaccat ccagaagaat atctccacct
    13621 tgaatacttt ctaagccgtt gaggcaacga aggagggtac ttttcccaca accagatgcc
    13681 cctaggatga caacaacttc cccctttttt gatttctaga gaaagtcctt ggaggatggg
    13741 attgtctccg aaggattttt ttagttcctt gatttctaag atagtttcag acatttagtt
    13801 tctccaatgt ttttctaagt gagtggatag tttggaaata gggtagcaaa ctgcgaaata
    13861 taagactaga atggttccat aaatccaaaa tgaagcagtt gggatggtca ggcgattgct
    13921 atcgatgatt tgttgtccaa ctttggtcac ttccacaacc ccaatcaaaa caactaatga
    13981 agtggtttta atcatccgag tgacaagatt gatagcctgc ggtagcagtc ttcttaagac
    14041 ttgtgggatg atgatgtggt agtaaagttg aacattagtc aagtcgagtg cctatccact
    14101 ttcaaactga tgtttaggga gagaagtgat agctccacgt accaagtctc ccatttcagc
    14161 tgttccccag agggtaaaaa tgataatagc tgaagtctca cctgagatat tgatattaaa
    14221 gtttcgagcc aagccaaagt aaacgatgaa gagtagcacc agctggggca tgatacggat
    14281 aaattccaga tacaatcgtg ttaaaaatcg tatgattcta gaatgggagg tcatgatgat
    14341 tcccatgact gttccgaaca tcatggataa gaggacagac aggatggata tcccaatcgt
    14401 aacgcccaac ccctgtaaga ttctcaggag attatttcct tgaaagagta cttggattcc
    14461 cgaatcctgc atggcgggtc ctcctttcta tccagctaaa gaccagtgag atgggtagca
    14521 gcatgatcag ataagcaact accaacatag ctagcgcaat gtctgtctca tagtagagac
    14581 caatcaaatc cttggcgacg tacatgaggt cggccaaagc cactgctgag aaaacagagg
    14641 tttccttgat aaggaaaatg acattggcac taaaggaggg gagtgccacc gctgttgctt
    14701 gcggaagaac cacatagcga aagacctgta gaggtgtcag accaatagcg aggccaatct
    14761 cctgctgggt ttgactgatg gcttccagcc cacttcggaa agattctgcc atataggagc
    14821 ctcctaaaaa gacaaggcca agcgttgcac agacttctga agataggaca atcccgattc
    14881 ggggaagacc gaagtagaga aagaagagtt gaatcaaaag gggcgtatta cgtgacaatt
    14941 caatgtaggc tgtcgctact tgcgccaaaa cagggattcg ataatgtcgg atgatactaa
    15001 cgattaaacc gagcagaaag gatcccaaaa ttccccaaac tgcaatatgc aaggtcagaa
    15061 agaatgcctt ttgatatagt ggtagatatt gttcaacaat ggaccaatcc aaaaatagaa
    15121 cctcccatct agaaataata cagttattgt agcacttaaa atcttctttg gataatatct
    15181 attttttatt gccgttataa ggatttttta ccatagacat aaaatttctg aaatttccaa
    15241 acaaaatatt tgaaaagttt tgaaaaagag ttaagatatt tttgtaatat acaaagtaaa
    15301 cgcttactta ttaaggagga cagtttatgt catacaaaac aagcaatgca gaaggtcatg
    15361 tagatttcat caatacctat gatttggaga caatggcgca acaagttatt cctaaagcag
    15421 catttggcta tatcgctagt ggggcgggag atactttcac ttctttccag tgattttagc
    15481 gtcaggttct ttttagtttt taaagattat ccgtgaattt cttgcttatt tatgataaaa
    15541 tgggagtatc gcaaaaaatg actcatcgta ttcaattttg agtaaaacta ggaggatccc
    15601 atgtctacag aacatatgga agaactaaat gaccagcaga tcgttcgccg tgaaaaaatg
    15661 gctgcgctcc gcgaacaagg aatcgatcct ttcggaaaac gttttgaacg tactgcaaat
    15721 tcacaagaat taaaagataa atatgccaac ctcgataaag aacaattaca cgataaaaac
    15781 gaaacagcta ctatcgcagg acgcttgata accaaacgtg gtaaaggaaa agttggtttt
    15841 gcccaccttc aagaccgcga aggccagatt cagatctacg ttcgtaagga tgctgtcggt
    15901 gaagaaaact acgaaatctt caaaaaagca gatcttggtg acttccttgg tgtcgaaggt
    15961 gaagtgatgc gtacggatat gggagaactc tctatcaagg caacccacat cacacacttg
    16021 tctaaggctc ttcgtcctct tcctgagaaa ttccatggtt tgacagacgt tgaaacaatt
    16081 taccgtaaac gttaccttga cttgatttct aatcgtgaaa gctttgaacg ctttgtcact
    16141 cgttcaaaaa tcatctctga aatccgtcgt taccttgacc aaaaaggatt ccttgaagtg
    16201 gaaacacctg ttcttcataa tgaagccggt ggtgctgctg cccgtccatt tatcacccac
    16261 cacaatgccc aaaacattga catggtgctt cgtatcgcaa ctgagcttca cttgaaacgc
    16321 cttattgtgg gtggtatgga acgtgtctat gaaattggcc gtatcttccg taacgaagga
    16381 atggacgcta ctcataaccc tgagtttact tctatcgaag tttaccaagc ttatgcagat
    16441 ttccaagaca tcatggactt gacggaaggc attatccaac acgctgctaa atcagttaag
    16501 ggcgatggcc cagtcaacta ccaaggtact gaaatcaaga ttaacaaacc atttaagcgt
    16561 gttcatatgg tggatgctat caaagaaatt actggtgtcg atttctggca agacatgact
    16621 ttggaagaag ctaaagctat cgctgctgag aagaaagttc cagttgagaa acactacact
    16681 gaggttggtc acatcatcaa tgccttcttt gaagagtttg ttgaagaaac tttaatccaa
    16741 ccaacctttg tctatggaca tccagtagct gtatctccac tcgctaagaa aaatcctgaa
    16801 gaccaacgct ttactgaccg tttcgagctc tttatcatga ctaaggagta cggtaatgcc
    16861 tttactgagt tgaacgaccc aatcgaccaa cttagccgtt ttgaagccca agctaaagcc
    16921 aaagaacttg gtgatgatga agcgacagga atcgactatg actacattga agctcttgaa
    16981 tacggtatgc caccaacagg tggtttggga atcggtatcg accgtctctg catgctcctc
    17041 actgatacaa caactatccg tgatgtattg ctcttcccaa caatgaaata aattcttatc
    17101 ctctggctct taccagagga ttttttgatt caaaaagaga ctgaatttaa ggagaaaatg
    17161 aagtgtagta tattgaagtt gaaatagtac actttgattt ctaagacatt gttagaaatt
    17221 ggtttaaatt ccctaatcaa tttgtgcatg ttttatttca ttttacgata gtacgctgaa
    17281 actgttcaaa aagtactaga aattgacttg gattccccaa ttgatttgtt cagattcact
    17341 ataaataaaa aattaataag tgggatagga agttagcgtc aactaggata gtatcttgct
    17401 taaacagtat atatgggatt gatataagtc cataggtcct attagaggat gttctggtgt
    17461 cttattcact tgctttttta tagtattagt agatagaatc agcaaataaa aaagtagttc
    17521 aaatgcctgg cagcaaaaaa tctcaacgat tcacttaata tagactaaag tttagagttt
    17581 aaggaaagta gggctagtat attgtatgaa aaaataagat ggtttttaag caaaactctt
    17641 gaaaatgatt gaaaaaagag ttattatagt tgtgtagtaa aaagcaaacg cttacttaat
    17701 caaggagggc attttatgtc atacaaaaca agcaatgcag aaggtcatgt agacttcatc
    17761 aatacctatg atttggagcc aatggcgcaa caagttattc ctaaagcagc atttggctat
    17821 atcgctagtg gggcggaaga tactttcact ttaagagaga atatccgcgc ctttaaccac
    17881 aaactcatcg ttcctcatac actttgcgat gttgaaaatc caagtacaga gattgaattt
    17941 gcaggtgaaa aactatcttc accaatcatt atggcgcctg ttgcggctca taaattggca
    18001 aatgaacagg gggaagtggc gactgcgcgt ggtgtgcatg agtttggttc tctttataca
    18061 accagctctt actctactgt tgaccttcca gagatttctg aagcccttca agggacaccc
    18121 cattggttcc aattttactt tagtaaggat gacggtatca accgccacat catggaccgt
    18181 gtgaaggctg aaggttataa agcgattgtc ttgacggcag atgctactgt aggggggaat
    18241 cgtgaagtgg ataagcgtaa tggttttgtc ttcccagttg gcatgccgat tgttgaagaa
    18301 tacctgccag aaggtgctgg taaatcaatg gactttgttt acaaatcagc taaacaacgc
    18361 ttgtctccac gcgatgtaga atttatcgct gaatactctg gtcttcctgt gtatgtcaag
    18421 ggaccacaat gccgtgagga cgttgaacgt tcgcttgctg caggagcttc tggtatctgg
    18481 gtaaccaacc acggtggtcg tcaaatcgac ggtggaccag ctgcctttga ctcgcttcaa
    18541 gaagtggcag aagcagttga tagacgtgtg ccgattgtct ttgactctgg tgttcgtcgt
    18601 ggtcaacacg tctttaaagc cttggcttca ggagcagact tggtagctat tggtcgccct
    18661 gttatttatg gcttggctct cggtggtagt gtcggtgtgc gtcaagtctt tgaacacttg
    18721 aatgcggaat tgaagacagt tatgcaattg tctggagctc agaccattga agatgtcaaa
    18781 cactttaagc tccgtcacaa tccatacaac ccaaccttcc cagttgaccc tcgtgactta
    18841 aaattgtatt gataaaacag attgcctcca ctgaatgtgg aggtttttct tcgtgtattg
    18901 gaagaataaa ttgctatcga aaactatagt aaaatgaaat aagaatagga caaatcaatc
    18961 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta ttctagtttc
    19021 aatctactat ataaagatat ttttcggtca aatatcttgc tagggctttc attttttgct
    19081 atactggttc agtaattaaa taatagagac atttggggtg ctttaagctg agatgatacc
    19141 cattgaacct gatacagtta agactggcga agggaaatgt gaaacgtttt ttcgtatggc
    19201 gaaatgaacg atctaatctt gtaagtcaac tctaattctt gattgtaatt ggagtttttt
    19261 gtttatataa actggatagg cttgtttagt tagctctctg caaatgctct cgatgtgctt
    19321 taaaaggatc aagtggaatt acgattttgc ttgatatttc ttggtgtttt attaattact
    19381 aacaagtaaa gagaggagaa gtaaatatgg aaacacaaaa ctatgcattt cagccaggtt
    19441 tgactgttgg agaattatta aaaagcagtc agaaggattg gcaggctgca atcaatcatc
    19501 gttttgttaa ggaacttttt gcggggacaa ttgagaataa ggtcttaaag gactatctga
    19561 ttcaagatta tcacttcttt gatgccttct tatccatgct gggtgcctgc gtagctcacg
    19621 cagataaact tgaatccaag cttcgttttg ccaagcaact aggctttctt gaagcagatg
    19681 aagatggtta tttccaaaag gcttttaaag agttaaaagt agcagagaat gactatctag
    19741 aagtgacttt gcaccctgta acaaaagcct ttcaggatct aatgtattcg gcggtggctt
    19801 catcagacta tgcccatctt ttggtcatgc tggtcattgc agaaggtctc tatttagact
    19861 ggggttctaa agatttggct ttacctgaag tctatattca ttcggaatgg atcaatctcc
    19921 acagaggtcc tttctttgca gagtgggttc aatttctggt tgacgaactc aatcgtgtcg
    19981 gtaaaaatcg agaagatttg acagaacttc agcaacgctg gaatcaagca gtcgctttag
    20041 aattagcttt ttttgatatt ggttacgatg tctagagaag gctcatgata tttacaaatt
    20101 tgatgaggta agactcttcg aaaatctctt caaaccacgt cagtttcacc ttgccgtagg
    20161 tatggttact gacttcgtca gtcttatcta caggttcaaa gcagtgtttt gagcaatctg
    20221 cggttagcct cctagtttgc tctttgattt tcattgagta taaatcattc aacgtaaatg
    20281 aaaaaaattt cttaacgaaa gatagagata aatcgaaatc agtagatcgt ataaagtgta
    20341 aaggaaggat ttcaatatga caagtttaaa attattaaaa gaaaaagcac cattggtcat
    20401 ttgtataacc aatgatgtag taaaaaattt cacagcaaat ggattagtag cactgggcgc
    20461 ctcaccagcc atgagtgagt ttccagcaga tttagaggat ttgttaaagt atgctggtgg
    20521 tttattaata aacataggaa cattgacaga tgaaaattgg aaattatacc aagctgctct
    20581 gaaaattgca gagaaatata atgtcccagc agttttagat cctgtagcct gtggagcagg
    20641 agaatataga aaaaaagtag cagatgatct aatcaacaat tataaactag cagcgattag
    20701 aggaaatgct ggcgagattg cctctttagt aggaatagat gtggcatcta aaggagtaga
    20761 tagtgcgggc gtagataata ttgacgaaat tgctctagca gcaaatgaga agttcaatat
    20821 tccaatagta gtaacaggtg aagtggatgc cattgctgtt aatggagaag tggtaacgat
    20881 tcataatggt agtgctatga tgccgaaagt cattgggaca ggatgcttat taggagctgt
    20941 agtagcaagc tttatcggac tagaaaaagg tcaagaattg aaatcattag aaacagcaat
    21001 gttggtttac aatatcgctg gagaaatagc agaaaaacgt cccaatggac atcttcctgg
    21061 aacatttaaa gttgaattta taaatgcctt atatgagatt acagatgaag atgtaaagga
    21121 attcaaaaga gtgaagtaag atgtttcata aagaattact aaaactatat tttatttgtg
    21181 gaacgactac ttgccaagga aaaaatctat atacagtcgt tgaggaagcc ttaaaaggtg
    21241 gtataacctt atttcaattt cgagaaaaag gtgagggtgc tttagaaggc ttagaaaaac
    21301 ttgagctagc tatccaaatt aaagaacttt gtaaaaaata caatgtgccg tttatcgtta
    21361 atgatgatat cgatttggca atggaaattg acgctgatgg cgtacatgta ggtcaagatg
    21421 atattggtgt tgatgaaatt agaaaattga tgccagataa aataattggt ctttctataa
    21481 gaaacgaaga agaatttcaa caatcaaaag ttgaatatgt agattatgta ggtgttgggc
    21541 ctgtatttga tacccagtca aaagatgatg ctggtggtgc tataggttat gaaggtcttg
    21601 aattgatgag aaaactattg ccacaaatgc ctttagttgt aattggtggg atacagacga
    21661 aacatattaa agacattata aagaccaatg ttgacggcgt ttcaatcatt tcggcaatat
    21721 cgtatgcaaa aaatatagaa aaaactgttc gggaaatgag tgaacaatag atatctatcc
    21781 ttggattcta agtaagtagg attttccttt tttaaaaagc tatgtctaga ttcagcttga
    21841 atggctaatt cattaaacag gtcatttgtt ttttgcaaaa gaaagatctg ctgtctttgt
    21901 gagtgcaagg ctgtatttcc agttcaattt cttgaactag tataaaatgt gtgttataat
    21961 aatcacataa ttaaataata aaggcatttg gggtgcttta ggctgagatg atacccattg
    22021 aacctgatac agttaagact ggcgaaggga aatgtgaaat gtttttttcg tatgtcgaaa
    22081 agaactgtct aatcttgtaa gctgaactct aattcgtatc tgtaattaga gttttttctt
    22141 ttacgaaact ggatgaagat gatatagtag attgaaataa gatgcgaaca aatcaattag
    22201 aaaattcaaa ttaatttcta ggaatatttt agcattcctg tgtactgttc taaattcaat
    22261 ctgctataca aagtatttag gtcggtcttc ttgagtgccc cacttttctt ttaaaaaagg
    22321 agttttttat gttgaaaaaa tggcagttaa aagatgttat cttgcttgct ttcttgtcta
    22381 tcttttttgg tggggttttc gttggttcag gatatgtgta taatattctc agtctactct
    22441 taacacctct tggtttgcag gcctttgcca atgaaatcct cttcggtctc tggtgtatgg
    22501 ctgcgcccat tgctgccatc tttgttccga gagtcggaag tgcaacgatt ggagaagtgc
    22561 tagctgcgct tgctgaagtc ctttatggta gccaatttgg tctaggagct cttttgtctg
    22621 gcttagttca aggtttggga agtgaatttg gttttatcgt aactaagaat cgctatgaaa
    22681 gttggctctc tctaactgct aatagtattg ggattacgct tgttagcttt gtctatgaat
    22741 acattaagtt aggttactac gccttttccc ttccgtttgt cctttcctta cttgtggtac
    22801 gttttatttc tgtttatttc ttctgtacca tcttggttcg tgccattgtc aaactctatc
    22861 atcagtttgc aactggagga aaagcataga tgggtctgga actacgagcg attcagtccc
    22921 caatcttctc tgagccgttt gattttactt ttcatgcgca agcctttacc ttgttagttg
    22981 ggagcagtgg ttcaggaaaa tccagccttt ttcaagccat tgcccaagtc agttctcttc
    23041 cctatagtgg tcaagtcctg atagatggga gcgaggtcag tcagctttct atcatcgcac
    23101 gtgtccagaa ggttggcatt ctctttcaaa atcccaatca tcaatttacc atggagaact
    23161 tgtttgagga gctgattttc accttggaga atatcggcta tcaccttcag gaaattgatt
    23221 ctaaaatagc agaggttgtc cagcaatgtc gttgcgaggc aatcttacac cgtcccattc
    23281 atcacctatc aggtggggaa aagcaaaaag cagcgctggc tgtcctcttt gccatgaatc
    23341 ctagggtcta tctcttggat gagcccttcg cttccattga ccgcaagagc agaatcgaga
    23401 tattggagat tctaaaagag ttggctcttg atgggaagac agttattttg tgcgaccatg
    23461 atttatctga ctataaagcc tatatcgacc atatggttga gctaagagac ggaaaactaa
    23521 gggaagtgtt tcaaatccct tcctatgaga tgacacaggt tgcttcaaag gaagttgctt
    23581 ctagcccgga actattccat atggatagaa cgacttgtga gtttggtaat cgccccctct
    23641 tttcaattgc tgatttcaca ttctatcaag ggatttcctg tatcctgggt gacaatggtg
    23701 tcgggaaatc aaccctcttt cggtctattc ttcaatttca aaagtataag gggcgcattg
    23761 catggaaggg gacagtcctg aaaaagaaaa agagtttgta tcgtgatctg actggtgttg
    23821 ttcaggaagc tgagaagcag tttatccgag tcagtctgcg agaggagctt caattagatg
    23881 gacctgattc tgaaagaaat cagcggattt ttcaagcttt acgatatttt gatttggagc
    23941 aggcagtcga taagagtccc tatcaattaa gtggtggtca gcaaaaaatt cttcagctct
    24001 tgaccatctt gaccagtaag gcttccgtga tcttgctaga tgaacctttt gcaggtttgg
    24061 atgatagagc ctgccattat ttttgcaagt ggattgtgga ggagaggaat caaggaagaa
    24121 gttttctgct cattagtcat cgtttagacc ctttgatttc tgtggttgat tattggattg
    24181 agatgactag tcagggtctt cggcatgtga aagaagtgac cattaccaaa ccacttacat
    24241 ctcagagtag caatacccaa ggggaggtga gatagtatgg tcaaagtagc aacccagaca
    24301 ccgattatca gtctcttctt gctgatttta tccttggaaa catctttcat tccttcgatt
    24361 gctctgaatc ttttggtagt cgcattttgt attctcttta tgctctatta ccgtcgattt
    24421 aaaatgttag cttggatgat catacttgcc attttaccat cttttgccaa ctactgggca
    24481 gttcagttac acggagatgc ttcacaggca gtcatgcttg gaacgagggc ctttgtgaca
    24541 gtttgtatcg gccttgtctt tgtttcctct atttcactaa aagagcttct cttgtacttg
    24601 gctcaaaagg ggctatcacg ctcttggtcc tatgccttga ttgtggtatt caattctttt
    24661 cctctcattc agcaagaaat caagtccctc aaagaagctt gcctattacg tggtcaagaa
    24721 ctacattttt ggtcgccctt gatttacagt aaggttctga tgacagtctt taggtggcgc
    24781 catctttacc tgagagctct atctgctcac ggatatgacg aacatgcaca gttgaagaat
    24841 agctatcgga ctttttatat tcctaaaaaa acaaaattaa tctacctgct tttcttttta
    24901 ttgcttcaaa ccagtctatt tttataaagg agttattatg gaatttacag atattgcgat
    24961 ggaattatcc aagaaagctt ggcaggcttc ctttcatcat ccctttattt tacaattaca
    25021 agaggggaat ttagaacctg ccattttccg ctattacctg attcaggatg cctactatct
    25081 gaaggccttc tcagaaatct atcatctttt ggctgataag acttcaaacc aagagatgaa
    25141 aagactcttg aaacaaaatg ctcagggttt agtggagggt gagttattta ttcgccaaca
    25201 atttttcaag gaaatggaaa tcagcgacca ggaaatggag caacatccaa tcgctccaac
    25261 ctgttatcat tacatttctc atatttatag gcaatttgca gaaccgaact tagccatcgc
    25321 ttttgcaagc ttgcttcctt gtccttggtt ataccatgat ataggcaaat cacttaatct
    25381 taaaccatca ccaaatcctc tctatcaaca atggattgaa acttatatta cggatgagtt
    25441 agagcaacag atcagagagg agggagcact ggtcaatcag ctctatcgag aaagtgatga
    25501 gacagataag caaaaaatgc tagatgcctt ccacatcagt gttcatatgg aagccaagtt
    25561 ttgggagatg gcttaccaac accagacatg gaagagcgat ttacagtctt tagaaaaagg
    25621 agaagaatag aaacatgaga aagcaccaac tacaagttca caaattgacc attttatcta
    25681 tgatgattgc ccttgatgta gtccttacac ctatctttcg gattgaggga atggcaccga
    25741 tgtccagtgt agtcaatatt ctagcgggaa tcatgatggg acctgtttat gccttggcta
    25801 tggctacagt gacagccttt atccgtatga cgactcaagg gattccgcct ttagctctca
    25861 caggagcgac ttttggagcc cttctagcag gtctctttta taagtacggt cgaaaatttt
    25921 acttttctgc cttgggagaa attgtgggaa caggtattat tggttctatt gtttcctatc
    25981 ctgttatggt actctttaca ggatcagctg ctaagcttag ctggtttatc tacacgcctc
    26041 gatttttcgg agcaaccttg attggtacag cgatttcctt tattgccttt cgatttttaa
    26101 tcaagcagga attctttaaa aaagtgcagg gatatttctt tagtgaaagg atagactgat
    26161 gcaggaattt acaaatcctt ttcctatagg ctctagttcc ctaattcact gtatgaccaa
    26221 tgagatttct tgtgagatgc tggcaaatgg gattttggct ctgggatgca aacctgtcat
    26281 ggcagatgat tcccgtgaag ttcttgattt tactaagcaa agtcaggctc tcttcatcaa
    26341 tttggggcat ttgtcagctg agaaggaaaa agcaatccgc atggcagctt cgtatgcaaa
    26401 ccaatcttct ctcccgatgg tagtagatgc ggttggcgta acgacttcat ccattcgtaa
    26461 gagcttagtt aaagaccttt tagactatag acctacggtc cttaaaggaa acatgtcaga
    26521 aattcgaagt cttgttggat taaagcacca cggcgttggg gtcgatgcga gtgctaaaga
    26581 tcaagaaacg gaggatttgc ttcaagtctt gaaagactgg tgtcagacct atcatggtat
    26641 gtctttctta gtcacaggtc ccaaggacct cgtcgtttcg aaaaatcagg tcgctgtact
    26701 gggaaatggc tgtgcagaat tagactggat aacagggaca ggagatttgg ttggagcctt
    26761 aacagccgtt tttctcagca aaggaaagac tggttttgaa gcttcttgct tagcagtctc
    26821 ttatctcaat atcgctgctg agaaaatagt tgttcaagga atgggattgg aagaatttcg
    26881 ttaccaagta ctcaatcagc tttcgctcct aagaagagat gaaaattggc tagataccat
    26941 caaaggagag gcttatgaat agagaagcac ttagactata tctggtaacc aatcgctatc
    27001 aagattccgt ggaaagcttt cttgcaaaag ttgagacggc ctgccgttca ggggttacca
    27061 tagtccaatt gcgagaaaaa aatctcacaa ccaatcaata ttatcaactg gcaaaacaag
    27121 tcaaggaaat aacagatgct tatcaggtac ccttgataat cgatgatcgg ttggatgttt
    27181 gtcttgcggt tgatgctgct ggtctgcata ttggagatga cgaactccca gtttcggttg
    27241 cccgacaagt cttgggtcct gaaaaaatcc tcggtgtcac cgctaaaacg gttaaaagag
    27301 ctctggaagc ggagaaatca ggtgcagatt acttggggac aggagccatt tttccgacaa
    27361 ccaccaagga aaatgcaccc atcaccctga tttcaacctt gaaaacaatt tgccaaacgg
    27421 ttgccattcc aatagttgct attggcggct tgacttcgga gaatattgat cagcttatgg
    27481 gcactggcat agctggtgta gctgttgtac gtgatttgat gcaagcagaa gatattgagg
    27541 caaaaacgca agccttttta acaaagttgc atgacattct ttcctaatta atactcaatg
    27601 aaaatcaaag agtaaactag aaagctagtc gcaggttgct caaagtactg ccttgaggtt
    27661 ttagataaga ctgacgaagt cagctcaaaa cagtgttttg aagttgcaga tggaagctgg
    27721 cgtagtttga agagattttc gaagagtata aaaactctct aattccctta aagtgggaac
    27781 tagagagttt ttttcttaat ctttaaaagt tgtatggttg actggaccag aaccatgacc
    27841 gagttgaggg gcatcttgaa tagcttttgt gataaaggcc ttggccttat caactgcctg
    27901 gtaaagactc ttgcccttgg ctagttcagc agtaatcact gcagcaaagg tacatccagt
    27961 accatgggtg tgacaggttt gaattcgtgg gctttcccag acaaattgtt cattcttggt
    28021 aaagaggaaa tctttagcac cacctttgag atgtccgcct ttgataacca cagactgagg
    28081 accaaattct tttaaaatca ggcgaccagc acgctgcatg tcttcggggt catggattga
    28141 aaaaccaaca atctcttctg cttcaggaag atttggcgta ataatagttg ctagaggtag
    28201 taagtttgtt ttgagatagt ctctagcact tgagtcaatc aaggcatctc cacttgtagc
    28261 aaccataaca ggatcaagga catagggaca atccagtttt ttaagatagg ggtggatgat
    28321 ttccatgatt tcagtagtag ccaacattcc agtttttaca gcctgaggtg gaatatcaga
    28381 aaagacactc tccaattggg ctttcaacat ttgaggagaa acgtgctcga ttagctgaac
    28441 acctctggta ttttgagcga caagactggt tacaacagcc attccataga catctctcgc
    28501 ttggaatgac tttaaatctg ccataatgcc agcaccacca ctagggtcag tccctgcaat
    28561 ggtcaaagca acgggtaaat aagtcatcta aaacctccca accaactgaa gtttgtattc
    28621 ttaagaacaa gctagtctgt tttagaaagg caatagaaga ctgctagtcc ccattatcat
    28681 ttccacttcc atcagctagc attatctaga ttgagtcaga gggatctaac agtcgttaat
    28741 ctcagcttta cgcaccccta gtggttgttt tcttttttct ttagtatagc atatttttat
    28801 tgtttatata gtaatatttg actgcaaatc gtttttcaaa tgattaaaat tctatttttc
    28861 gaagaaaata ttatttctat aattgacaaa tgtagatttt aagagtatac tgatgagtgt
    28921 aattgacaaa tgtagatttt ggaggtatgg taatgcagat ttcagatgca gaatggcagg
    28981 tcatgaagat tatttggatg cagggggagc agactagtac agatttgatt agggttttgg
    29041 cagagcggtt tgactggtcc aagtccacgg ttcagacact tttggctcgt ctggttgaga
    29101 aagagtgttt gactcggaaa aaagaaggca agtcctttgt ttattcagcc cttttaactc
    29161 tagaccaaag tcgggattta cttgtccaag atatcaaaga caaggtttgt tcccgtagga
    29221 ttaggaattt gttggctgac ttgattgtag aatgtgaatt tactcagact gacttggaag
    29281 acttggaagc tgtgatttca gagaagaaat caagtgctgt aacagaagta agatgtaatt
    29341 gtatgtaaag gagacgtcat gttaaatagt attgtaacca ttatttgtat tgcccttatc
    29401 gcatttatct tgttttggtt tttcaaaaag cctgaaaaat ctggacaaaa agcccagcaa
    29461 aaaaacggat accaagagat tcgagtggaa gtcatgggag gctatactcc tgagttgatt
    29521 gtcctaaaga aatcagtgcc agcacgcatt gtctttgacc gcaaggatcc ttcaccatgt
    29581 ctggatcaaa ttgtttttcc agattttggt gtacatgcga acctgccaat gggggaagag
    29641 tatgtagtgg aaatcacgcc tgaacaggct ggagagtttg gctttgcttg tggtatgaac
    29701 atgatgcacg gcaagatgat tgtagagtag gtggagacta tgacagaaat tgtgaaagca
    29761 aacttagaaa atggcattca aaaaatccgt atccgagctg aaaaaggcta tcatccagcc
    29821 catatccagc ttcaaaaggg aattccagct gagattacct ttcatcgtgc tactccttca
    29881 aactgttata aggaaattct gtttgaagaa gaaggtatct tggaagcaat cggcgtagat
    29941 gaggagaaag tcattcgttt tacgcctcaa gaattagggc gacatgaatt ttcttgtggc
    30001 atgaagatgc aaaagggaag ctatacagtc gttgagaaga ctcgaaaatc tctatctctc
    30061 ctgcaacgtt tttggattac tagtatcttt actgtgcctc ttgtgattct catgattggg
    30121 atgttgacag gtagcattag tcatcaagtc atgcattggg gaacctttct agcaacaacg
    30181 cctattatgt tagttgcagg taagccatat atccagagtg cttgggccag ttttaaaaag
    30241 cacaatgcca acatggatac cttggttgcg ctgggaactc tagtggctta tttctatagc
    30301 ctagttgctc tctttgctgg tctccctgtt tacttcgaaa gtgctggatt tatcctcttt
    30361 ttcgttcttt tgggagcagt ttttgaggaa aaaatgagaa aaaatacgtc ccaagctgtg
    30421 gagaaattac tggacttgca agctaaaacc gcagaagtct tgagtgatga tagttatgtc
    30481 caagttcctt tggaacaagt caaggtaggc gacctgattc gagtgcgtcc cggtgaaaag
    30541 attgctgttg atggtgtcgt agtagaaggt gtctctagta ttgacgaatc catggtgaca
    30601 ggtgagagtc tgcctgtgga caagacagtt ggagatactg tcattggctc aaccatcaat
    30661 catagtggaa cgcttgtctt tagagcagaa aaagttggct cagagactgt tttggctcag
    30721 attgtggatt ttgtgaagaa agctcagaca agtcgtgcgc cgattcagga cttgacggat
    30781 aagatttcag ggatttttgt cccagtagtt gtcattttag gaatcatgac cttttgggtt
    30841 tggttcgtct tgctcaggga tagtgtggtc gtgcttggag ctagctttgt gtcctctctt
    30901 ctctacggag tggcggtttt gattatcgcc tgtccttgtg ccttgggact tgcaacaccg
    30961 acagccctta tggtggggac aggacgtagt gccaagatgg gggttctcct caaaaatgga
    31021 actgtcttac aggaaatcca gaaagttcaa actcttgtct ttgataagac cgggactttg
    31081 acggaaggga aacctgtggt aacagatatc atcggcgacg aagtagaagt gtttggattg
    31141 gcagcctcct tggaagatgc ttctcaacac ccactggctg aggctatcgt taagcgagcg
    31201 agtgaagctg gacttgagtt tcaaactgtt gaaaattttc aggccttgaa cgggaaaggt
    31261 gtttcagggc gaatcaatgg aaaacaagtt ttacttggaa atgctaaaat gctggatggc
    31321 atggatattt ctaatactta tcaagataaa ctagaagaac tagaaaaaga agctaagaca
    31381 gttgtgtttt tagctgttga caatgaaatc aaaggcttgc ttgctttgca agatattcct
    31441 aaggaaaatg ctaagctagc catcaatcag ctaaaaaaac gtggtctccg aacagtcatg
    31501 ctgacaggag acaatgctgg tgtggcgcgt gctattgcag atcaaatcgg aattgaagag
    31561 gtcattgcag gcgtcttgcc agaagaaaaa gcccatgaaa tccataaact gcaacagtca
    31621 gggaaagtag cctttgttgg ggacggtatc aatgacgctc ctgcccttag tgtagcagat
    31681 gtggggattg ctatgggagc tggaacagat atcgccatcg agtcagcaga tttggtgttg
    31741 acaaccaata atcttttagg agtggttcgt gcctttgata tgagtaagaa aacctttcat
    31801 cgaattctac tcaatctttt ctgggctttt atctacaatg ttgtcggaat tccgattgca
    31861 gcaggagtct tttcaggtgt tggactggct ctcaacccag aattggcagg tctagccatg
    31921 gcctttagtt ctgtatctgt tctgaccagt tcccttctgt taaattttag taaaatagac
    31981 taaaagtaat gactagattt ctttgttata aaacagaaat gacagaactt taaaaactgt
    32041 attagaatag agaatagaga gttttgagca gatttttaga aaagtcagca taaatatgat
    32101 acagtggaat agtaaaaatt tggagaacgt ttccaattct atgtaatcgt attctccaaa
    32161 tctaaaaaaa ttgaaggaga gttatcatta tgactcaagg gaaaattact gcatctgcag
    32221 caatgcttaa cgtattgaaa acatggggcg tagatacaat ctacggtatc ccatcaggaa
    32281 cactcagctc attgatggac gctttggctg aagacaaaga tatccgcttc ttacaagttc
    32341 gccacgaaga gacaggtgct cttgcagcgg ttatgcaagc taaattcggc ggctcaatcg
    32401 gggttgcagt tggttcaggt ggtccaggtg cgactcactt gattaacggt gtttacgatg
    32461 cagctatgga taacactcca ttcctagcga tccttggatc acgtccagtt aacgaattga
    32521 acatggatgc tttccaagag cttaaccaaa acccaatgta caacggtatc gctgtttaca
    32581 acaaacgtgt agcttacgct gagcaattgc caaaagtaat tgacgaagcc tgccgtgctg
    32641 caatttctaa aaaaggtcca gctgttgttg aaattccagt aaacttcggt ttccaagaaa
    32701 tcgacgaaaa ctcatactac ggttcaggtt catacgaacg ctcattcatc gctcctgctt
    32761 tgaacgaagt tgaaatcgac aaagctgttg aaatcttgaa caatgctgaa cgcccagtta
    32821 tctatgctgg atttggtggt gttaaagctg gtgaagtgat tactgaattg tcacgtaaaa
    32881 tcaaagcacc aatcatcaca actggtaaaa actttgaagc tttcgaatgg aactatgaag
    32941 gtttgacagg ttctgcttat cgtgttggtt ggaaaccagc caacgaagtg gtctttgaag
    33001 cagacacagt tcttttcctt ggttcaaact tcccatttgc tgaagtttac gaagcattca
    33061 agaacactga aaaattcatc caagttgata tcgaccctta caaacttggt aaacgtcatg
    33121 cccttgacgc ttcaatcctt ggtgatgctg gtcaagcagc taaagctatc cttgacaaag
    33181 taaacccagt tgaatcaact ccatggtggc gtgcaaacgt taagaacaac caaaactggc
    33241 gtgattacat gaacaaactc gaaggtaaaa ctgagggtga attgcaattg tatcaagttt
    33301 acaatgcaat caacaaacat gctgatcaag acgctatcta ctcaatcgac gtaggtaaca
    33361 ctactcaaac atctactcgt caccttcaca tgacacctaa gaacatgtgg cgtacatctc
    33421 cactctttgc gacaatgggt attgcccttc ctggtggtat cgctgctaag aaagacaatc
    33481 cagatcgcca agtatggaac atcatgggtg acggagcatt caacatgtgc tacccagacg
    33541 ttatcacaaa cgttcaatac gaccttccag ttatcaacct tgtcttctca aatgctgagt
    33601 acggcttcat caagaacaaa tacgaagata caaacaaaca cttgtttggt gtagacttca
    33661 caaacgctga ctacgctaaa attgcggaag ctcaaggagc tgttggattc acagttgacc
    33721 gtatcgaaga catcgatgca gttgttgcag aagctgttaa attgaacaaa gaaggtaaaa
    33781 ctgttgtcat cgatgctcgc atcactcaac accgtccact tccagtagaa gtacttgaat
    33841 tggatccaaa acttcactca gaagaagcta tcaaagcctt caaggaaaaa tacgaagcag
    33901 aagaactcgt accattccgt ctcttcttgg aagaagaagg attgcaatca cgcgcaatta
    33961 aataattcct ctcgccgaaa atcaaatatg aaacttgtag actttattct ttgattttca
    34021 tagagcagaa ctttaaaaga tcggagcaat ccggtctttt tatggaggag agtaaatgaa
    34081 tttaaatcaa ttagatatta tcgtttcaaa tgttccccaa gtctgtgctg acttggagca
    34141 tatcttggat aaaaaggcag attatgctga tgatggtttt gctcagttta cgattggtag
    34201 tcactgcctt atgttgtcac aaaatcattt ggttcctttg gaaaactttc agtcaggaat
    34261 cattattcat atcgaggttg aggatgtaga ccagaactac aaacggttga acgagcttgg
    34321 tataaaggtt ttacacggac caactgtaac cgattgggga acagagtcct tattagttca
    34381 aggacctgct ggtctagtgc ttgattttta tcgtatgaaa taggtcgcgt agtcatttga
    34441 cgttaacctt agctattttt aaaatagaaa ttgagaatat gaactattga aagatcggag
    34501 caatccggtc tttttatata aagaaattgc atataatact catctgcttt caaaaagtat
    34561 tctagtccat ctctgattaa cgatggactt tatcacctcc ttctccagtc cttgtatgac
    34621 atcttggagt tgattcatga catcttccaa agttcgaaag gctttattct taaatccacg
    34681 tttatgaatc tctttccaca cttgttcgat gggttcatct ctggtgtgta tggaggaata
    34741 aatgcaaaac caatattagt cggagtcttt ataagatttg cccatcagac gaaatagaat
    34801 gatttgaagg catttatgat atttagctgt acgagagtct ttaaaaagtg ttttgatggt
    34861 ttggatttct tctttagttg atttcatatc actattatat aatgcttttt gattttagta
    34921 tagtattatc gtagaaaatg gactcggtgc tatggataca ccggatgaga atggttatgt
    34981 agcagatgac taccggatta cttacttaga ggcccacatc aaggccatgc gagatgccat
    35041 ttacaaagac ggggttgact tgcttggtta tacgacatgg ggctgtatcg attcggtttc
    35101 agctggcaca ggggaaatga ataagcgcta tggctttatc tatgtagatc gagataatgt
    35161 aggaaatggg actctcaaac gtagcaagaa gaagtccttc tattggtaca tgtcatttat
    35221 agcaatggtg taagcatcga gtagagcaca tttgtttact atttttataa aatcttctcc
    35281 ctgctttata agatgtaaaa aagagttcaa atggaactct ttttttgcta taatgagggg
    35341 agaaaaatca gacaggagat taagatgtca gaaccattat ttttacaatc agttatgcaa
    35401 gaaaaaatct ggggtggtac caagctacgt gatgagtttg gctacgacat cccaagtgaa
    35461 aaagtcggag agtactgggc tatctcagct catctaaatg gtgtttctaa agttgccaat
    35521 ggtcgttacg agggaacaga tcttgctact ttgtatgcgg aacaccgtga attatttggc
    35581 aatcgtcctg agcctgtatt tccgcttttg actaagattt tggatgctaa cgactggctc
    35641 agcgttcaag ttcacccaga cgatgcttat ggactagagc atgaaggcga acttggaaaa
    35701 acagaatgct ggtacatcat cgctgcggat gaaggttcag agattatcta cggccacaat
    35761 gccaagtcaa aagaagaact ccgccagcaa atcgaggaca agaactggga taccttgctt
    35821 accaaagtcc ctgtcaaggc tggagatttc ttctatgtac caagtggcac catgcatgct
    35881 atcggtactg gcatcttgat tcttgaaacc caacagtcta gtgatacaac ttaccgcgtc
    35941 tatgactttg accgaaagga cgataagggc aacttgcgtg aacttcacct tgaaaaatcc
    36001 atcgatgttt tgaacattgg cgagccagca aatagccgtc ctgtaactgt taaagcagat
    36061 aatttgcgtt ccactttact tgtttctaat gatttcttcg cagtttacaa gtgggaaatc
    36121 actggaaaag ttgattttga gaagacagct gattacagtt tgtttagtat tttagctggc
    36181 caaggtcaac tgactgttga tggaaaaaac tatccaatcc aaaaagggag ccactttatc
    36241 ctaccaagtg atgttgaatc ttggacttta gaagggcaag atttagaatt aattgttagt
    36301 catccataaa aaagaaaggg cctgagttca ttactcaagt ccttttgatt acataaattg
    36361 ggcgatgaag accacgatga tgattggaat gacgaaacga agaaggaaga gccagacttg
    36421 gaacagtcct tgtttccatg ctctttcatc gagatggagt tcctccattg caagagcctt
    36481 tttaaagata tagcctgtaa aaagtgaaag gcagagagct ccaaatggca tgagaagatt
    36541 ggaaaccaag aaatccatgg catcaaagaa agttttacca aagatgtgaa catccgccat
    36601 aactccatag gatagggctg aaggaatgcc aaagacaaag gtcaaaattc ctaaaataac
    36661 actccatttg gcacgtttgc tgttgtcctg attggtgata ttgtctacat tgatttccag
    36721 cataacgaca gaagaagtga cagtcgcaaa gaggaagagg acatagaaaa tggttccaaa
    36781 aggcatcttg tcaaagagtt gaggcaagac gataaagacc aagctcggtc ccccttcaga
    36841 ctggatattg aagggggacc gagcttggaa aatggctaga cctgccatga tggataccga
    36901 gatattcatg gctacgatgg agattcttga ctggaccaga ttggttttct tgtccaagta
    36961 agaagcatag gtcaacatgg ctgtaacccc tagtgagagg gcaaagaaag attgtctcag
    37021 agcatagagg agaccagcgc tagtcagttt tgaaaagtct ggtttgagga agtaaagaac
    37081 cccttccatg gcatttgaca agctgagaga gcgaccgatg ataacaacaa agatgataaa
    37141 gagcaggggc atcatgactt tcgaagctct ttcaatccct ttttgaaccc cacgtgatac
    37201 aatgaagata ttcaatagga taaaggccgc ttgagctcct agggcaatgg ctggatttga
    37261 aatgatcaga cttcctgcga aacaaaatat ggcatagtag ttctatgaat gatgaagcaa
    37321 gtaaacaact aactgatgca cgatttaagc gtcttgttgg tgttcagcgc acgactttta
    37381 aagagatgtt agctgtatta aaaacagctt atcaacttaa acacgcaaaa ggtggacgaa
    37441 aacctaaatt aagcctagaa gaccttctta tggccactct tcaatatgtg cgagaatatc
    37501 gaacttatga agaaattgcg gctgattttg gtatccatga aagcaactta ctccgtcgga
    37561 gccaatgggt tgaagtaact cttgttcaaa gtggttttac ggtttcaaga actcctctca
    37621 gttctgagga cacggtaatg attgatgcga cggaagtaaa aatcaatcgc cctaaaaaaa
    37681 caattagcga atgattctgg taaaaagaaa tttcacgcta tgaaggctca agcgattgtc
    37741 acaagtcaag ggagaattgt ttctttggat atcgctgtga actatagtca tgatatgaag
    37801 ttgttcaaaa tgagtcgtag aaatatcgaa caagctggta aaatcttggc tgacagtggt
    37861 tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc cagcaaactc
    37921 aagccgctaa cagctgaaga taaagcctat aaccatgcgc tatctaagga aagaagcaag
    37981 gttgagaaca tctttgccaa agtaaaaacg tttaaaatat tttcaacaac ctatcgaaat
    38041 catcgtaaac gcttcggatt acgaatgaat ttgagtgctg gtattatcaa tcatgaacta
    38101 ggattctagt tttgcaggaa gtctaataga gtatgaacct gttctcgtat ttcttcgaga
    38161 gctaagttac tttcaagaat aatatttcca ctttgaatat aagttcgaac ttgttgaaaa
    38221 tcagcttctg tcaagatatc tactagataa gacattttag ggatagcatt ttttccatta
    38281 ggagtgactc cccttagcaa gataatatgt tccaaagtag ttcctttctt tttttggggg
    38341 gattgttcca tttagtaatg tatatttaga ttggatttgc tcccgccacc cagccggtac
    38401 agagggcaga agtgatgtta aagccacccg tgtgggcatt gatatccata acttcgcctg
    38461 caaagtggag gccaggtacc agcttacttt caagggtttt aggattgatt tccttgagac
    38521 tgactccacc cttggtaaca aaggactttg caagggacat ttttccagtt acaggaattt
    38581 taagttcttt aatggactga acaagttgtt ctcgttcctt ttcagtcagc tgtttgactt
    38641 tttcaggata tccttgtaca aaaaattcgg ccaagcgttc tggtaacaag gtttttaaag
    38701 cgtttttcaa ggatttttcc cgattttctt ctagaaatgt aaccaagtcc ttctcagaaa
    38761 gttgaggcaa aacatcgagt gagagaacct ccccaccttt gacaaagcta gacatgcgta
    38821 gggcagcagg acctgacaaa ccaaagtggg taaagagtaa atcatgagtg atgacatgct
    38881 taccataact tagggtcaca tcgtccagag aaatcccttg taaggcttta tgtggaaaat
    38941 ctgttaataa aggactttca gcagcctcaa gctcggtgat ggtatgctta aaatggcgag
    39001 caatctcgtg accaaaacca gtcgaaccag tcgaaggata agacttacca cctgttgtga
    39061 caatgagttt ctcacaagtg aaggtttgat ccgctgactt aaggacaaac tggtcatcta
    39121 cttttttaac agaaacgatt tctatttgag tagcaacttg accacctagt tcggtgattt
    39181 tcttttccaa agcttcgata atagtccgag acttgtcact ggctggaaag acgcgtccgt
    39241 ggtcttcgac cttaagttta acaccatttt ctgtaaaaaa gttgatgatg tcatgattat
    39301 cgaactggga gaaaacactg taaagaaagc gtccgtttcc aggaattcca gctagcaggt
    39361 tgtctaagct accattgttg gtcacattgc aacgtccccc accagtccca gctaattttt
    39421 ttccaagttt ccgatttttt tcgatgagga gggttttctg tccataaaag ctactggaaa
    39481 tcgtagccat cataccagca ggtcccccac cgatgacaat agtatcaaaa tgtttcatag
    39541 ctctattgta ccacaaaaaa acaagagatg atggtcacct cttgtcaaga atgcaattaa
    39601 tcaatttcat agcccatcag caaaccgccc tcttctgcat agaaactgca gagaccagag
    39661 gttggtagaa ttttaatatc cgcttgtggg aaggtttcac ggattcgctc tgagagctgt
    39721 tgacaacatt tttcgttatt gcgttgggcc atgacaatac ggccaccagc atatccagct
    39781 tttactaact catcataggc agcttgaact gatttctttg atccccttgc tttttgtagc
    39841 aattcgagag ttccagtttc actagctttt ccgaccatac gaatgttgag aaggccaact
    39901 accgtaccga taagcttact caaacggccg ttcttcacca agttatcgac tttggctagg
    39961 acaaagagca acttagtttt ttcttgatag gcggtgatag cttcaaccac ttcttcaaaa
    40021 gacaagcctt ggtcaatcaa gtcattcaat ttttctacga gtaggtcaac ttcaccacca
    40081 gcagataaac tatcaatcac atgaatctta gtgtcaggat ggtcttccag ataaatattc
    40141 tttgctagtt gagcgctatt gtgactgcca gaaagggtac ctgtgatggt tactaggaaa
    40201 atgtttttgg caccttcaaa tgctcgcaaa tagtcatctg ggcttggaca agctgatttt
    40261 gaagcttctg cagttgcata catggtttcc atcatttggt caatatcgag actggcgtca
    40321 tcaacaaaga cctgatcagc tacttgaatg gttaagggga cacttacaaa ggttgtgtta
    40381 atagctggtg ttggcagttg acgataatca caaccagagt cagcaataat cttccaagtc
    40441 atagaaattc tccatctttg tcagttatac attgacaaag gttctgtctt tttttacaat
    40501 tatatcatga aaactcttga aacaaaagca tcatccgtct gttgtgacaa gtagaaagaa
    40561 aatgttatgt ctgaacgtag aatctctgaa aagtctcttg aaaatctcag aaaatcaaac
    40621 caagaatcca atttattaac cagagaagcc attgaaacag ccctcttgca actcttggaa
    40681 aaaaaggagc tgaccaagat tagtatttct gaattggtca aacgtgcagg tgtttcgcgt
    40741 gcggcctttt atcgcaatta tgactccaaa gaggaaattt tagagagcgt ctttaaacga
    40801 actgtccaca atattatgga acagctgcat cattacgatt taaagacaga cctttatttg
    40861 gtttgggttc accttttccg ggaggccaga aaggaagcta gagtaattca attggccttg
    40921 gattaccatc tggaaaaaat ctttgtccaa gccatgcagg aatttctaga aaaataccat
    40981 gggaaatcaa aaggtgtcag ctcttatctt cattccttct ggagctcagc catcgtctct
    41041 gtccttctaa aatggatcaa ggatggcatg aaggtaccag ctgaaaagat tgcagattta
    41101 ggtttaccat tttttaaaaa atagagaaaa aggagaaaag agatgactga aaaaagactg
    41161 gcctgggatg agtattttgc agcccaagcc ctactaattg cgaatcgttc cacttgtaaa
    41221 cgtgctaaag tgggcgcgat tctggtaaaa gataataagg ttatttccac tggttacaat
    41281 ggttcggtgt cagggactga gcattgtatt gatcacgaat gtttggtcat tgaaggccac
    41341 tgtgttcgca cccttcacgc tgaggtcaat gctatccttc aaggtgctga gcgtggtgtt
    41401 cccaaaggct ttacagccta tgtaacccat tttccttgtc tcaactgtac aaaacaattg
    41461 cttcaggtcg gctgcaagcg cgtggtttat atcaaccagt accgaatgga cgactacgcc
    41521 caataccttt atcaagaaaa agggacagaa ttgacccatt taccacttga gacagtacag
    41581 acagctctta aagaggctga tctaatgtaa aaattatcaa aaataaatgg cttagaaaga
    41641 tttttaaacc gttttttggt ataataagaa gaataaattg aaagaaggaa ttccaaaaat
    41701 gggaaaaatt gaagttatta atcacccact gattcaacac aaattgtcaa tcttgcgtcg
    41761 tacagatact tctacaaaag cttttcgtga gctagtagat gagattgcaa tgttgatggg
    41821 gtatgaagta cttcgtgatc ttccactaga agatgtggaa atcgaaacac caattacaaa
    41881 aacagttcaa aaacaattgg caggtaagaa attggccatc gtcccaatct tgcgtgcagg
    41941 tatcgggatg gttgatggtc tcttgagctt ggttccagct gctaaagttg gccacatcgg
    42001 tatgtaccgt gatgaagaaa cacttcaacc agttgaatac ttggtgaaat tgcctgagga
    42061 cattgaccaa cgtcaaattt ttgtagtaga cccaatgttg gcaacaggtg gctcagcaat
    42121 cttggctgtt gattctctta aaaaacgtgg cgcatcaaat atcaaatttg tctgccttgt
    42181 atctgctcca gagggtgtaa aagcccttca agaagctcat ccagatgtag aaatctttac
    42241 agcagccttg gatgaacgtt tgaacgaaca cggttatatc gttccaggtc ttggagatgc
    42301 tggagaccgc ttgttcggta caaaataaga tcgaaaagaa gaatgacttg gaaaagtatt
    42361 tctagtcacg aaaggaggtt gggtttttgt ttctgtctaa tgaaagcaga gcaaaaattt
    42421 gacctttttt gaccaagata ttataatagt cttatcttca gtcatttgac caacaaaatt
    42481 aaaactcaaa aggagaaatg aatgattcct gtagttattg aacaaacaag ccgtggagaa
    42541 cgttcttacg atatttactc acgtcttctc aaagaccgca tcattatgct gacaggtccg
    42601 gttgaagaca atatggctaa ctctgttatt gcccaattgc ttttcttgga tgcccaagat
    42661 agtacgaaag atatttacct ttatgtcaat acaccaggtg gttctgtttc agctggtttg
    42721 gcaatcgtag ataccatgaa ctttatcaag gcagatgtcc aaaccattgt tatgggaatg
    42781 gctgcatcta tggggactgt catcgcatca agtggggcaa aaggcaaacg tttcatgctt
    42841 ccaaatgctg aatacatgat tcaccaacca atgggcggta caggtggtgg tacccaacaa
    42901 actgatatgg ctatcgctgc agaacacttg ctcaaaactc gtaatacctt ggaaaaaatc
    42961 ttggctgaaa attcaggtca gtcaatggaa aaagtccatg cagatgcaga acgtgataac
    43021 tggatgagcg cccaggaaac acttgaatat ggctttattg atgaaattat ggccaacaat
    43081 tcattgaact aatgatgata gaaggcaaac tcgactgggt ttgctttttt tggtataata
    43141 gggagagatt tcttagaaag aggatttatc atgtttgaaa aagtcaatcg ctctggcttg
    43201 attatctatc tttactataa tcgtgatgcc aaaaaactgc aggattatgg agatattacc
    43261 tatcattcca agaaacatcg ttacttacaa ctctatgttc caactcaaga agtggagcaa
    43321 ttggtcggac gcttgagcaa ggaaaaattt attaaaaaag ttagggtttg tcatatccaa
    43381 gagttggaaa caccctttgt gggcaatctt tatcgatagg aaaacgttat catcgaaaaa
    43441 gttcaaggaa aacattgaca attttctgat aattcggtat attcttaaca gactatttaa
    43501 gaaataagga gacaaaaaga tgaagaaaaa atttgcccta tcgtttgtgg cgcttgcaag
    43561 tgtagcactt cttgcagcct gtggagaagt gaagtctgga gcagtcaaca ctgctggtaa
    43621 ctcagtagag gaaaagacaa ttaaaatcgg gtttaacttt gaagaatcag gttctttagc
    43681 tgcatacgga acagctgaac aaaaaggtgc ccaattggct gttgatgaaa tcaatgccgc
    43741 aggtggtatc gatggaaaac aaatcgaagt agtcgataaa gataataagt ctgaaacagc
    43801 tgaggctgct tcagttacaa ctaaccttgt aacccaatct aaagtatcag cagtcgtagg
    43861 acctgcgaca tctggtgcga ctgcagctgc ggtagcgaac gctacaaaag caggtgttcc
    43921 attgatctca ccaagtgcga ctcaagatgg attgactaaa ggtcaagatt acctctttat
    43981 tggaactttc caagatagct tccaaggaaa aattatctca aactatgttt ctgaaaaatt
    44041 aaatgctaag aaagttgttc tttacactga caatgccagt gactatgcta aagggattgc
    44101 caaatctttc cgcgagtcat acaagggtga aatcgttgca gatgaaactt tcgtagcagg
    44161 tgacacagac ttccaagcag cccttacaaa aatgaaaggg aaagactttg atgctatcgt
    44221 tgttcctggt tactataatg aggctggtaa gattgtaaac caagcgcgtg gtatgggaat
    44281 tgacaaacca atcgttggtg gtgatggatt caacggtgag gagtttgtac aacaagcaac
    44341 tgctgaaaaa gcatcaaaca tctactttat ctcaggcttc tcaactactg tagaagtttc
    44401 agctaaagct aaagccttcc ttgacgctta ccgtgctaag tacaatgaag agccttcaac
    44461 atttgcagcc ttggcttatg attcagttca ccttgtagca aacgcagcaa aaggtgctaa
    44521 aaattcaggt gaaatcaaga ataaccttgc taaaacaaaa gattttgaag gtgtaactgg
    44581 tcaaacaagc ttcgatgcag accacaacac agtcaaaact gcttacatga tgaccatgaa
    44641 caatggtaaa gttgaagcag cagaagttgt aaaaccataa tagaaaaatg ttgaaatagg
    44701 gaatgagcct ttgactcact ccctgtttcg atatttaata ctcttcgaaa atctcttcaa
    44761 actgcgtcaa cgtcgccttg gattatatat gtgactgact tcgtcagtct tatctacaac
    44821 ctcaaagcag tgctttgagc aacctgcggc tagtttccta gtttgctctt tgattttcat
    44881 tgagtataag aacctatcaa aaagtgaggg aaacccctcg gaattataaa tagaaagagt
    44941 gaatcttatg ctccaacaac tcgtaaatgg tttgattcta ggtagtgttt acgcgctgtt
    45001 agccctagga tataccatgg tttacggaat tatcaagctc atcaacttcg cccatggtga
    45061 tatttatatg atgggagcct ttatcggtta tttcttgatc aattctttcc aaatgaattt
    45121 ctttgtagcg cttattgtag ctatgctagc gacagctatt cttggtgtcg tgattgagtt
    45181 tcttgcttac cgacctttgc gccactctac tcgtattgct gttttgatta cggctattgg
    45241 ggtttctttc ctattggagt atggaatggt ctatctggtt ggtgccaata cccgtgcctt
    45301 ccctcaagcg attcaaacag ttcgatatga tttgggacca attagcttaa caaatgtgca
    45361 gttaatgatt ttgggcattt ccttgatttt gatgattttg ttacaagtca ttgtccaaaa
    45421 gactaagatg gggaaagcca tgcgtgcagt atcagtagat agcgacgcgg cgcaattgat
    45481 ggggatcaat gtaaaccgta cgattagctt taccttcgct ttgggttctg ctcttgcggg
    45541 tgcggctggt gttctgattg ctctttatta taactctctt gagcctttga tgggggttac
    45601 tccaggtctt aaatctttcg ttgccgcagt acttggtggt atcggaatta ttcctggtgc
    45661 ggctcttggt ggctttgtga ttggtctatt ggaaaccttt gcgacagcct ttgggatgtc
    45721 agatttccgt gatgccattg tttatggaat cttgttgttg atcttgattg tccgcccagc
    45781 tggtatcctt ggtaagaatg tgaaagagaa ggtgtaaacg atgaaggaaa atttaaaagt
    45841 taatattcta tggttactcc ttttgttagc tggctatagc ttgattagtg tactggtttc
    45901 agtcggagta cttaatctat tctatgtaca gattttacaa caaattggaa ttaatattat
    45961 tttggctgtt ggtctcaact taatcgttgg tttttcagga caattttcac ttggtcatgc
    46021 tggtttcatg gcgattggtg cctatgccgc agctattatt ggttctaaat caccaaccta
    46081 cggtgccttc tttggagcta tgcttgtagg ggctttgctt tcaggagcag ttgccttact
    46141 tgtcggcatt ccaaccttgc gcttgaaggg ggactatctt gcggtagcaa ctctgggtgt
    46201 ttctgaaatt atccgtatct ttatcatcaa tggtggaagt cttacaaatg gtgcggcagg
    46261 tatcttaggg attcctaact ttacaacttg gcaaatggtt tacttctttg tcgtgattac
    46321 aaccattgca accttgaact tcttgcgtag cccaattggc cgttcaaccc tctctgttcg
    46381 tgaagatgaa atcgctgctg agtcagttgg ggttaatacg actaaaatta aaatcatcgc
    46441 ttttgtcttt ggtgccatta ctgcaagtat tgctgggtca cttcaggcag gatttatcgg
    46501 gtctgttgta ccgaaagatt acaccttcat caactcaatc aacgttttga ttattgttgt
    46561 atttggtgga ctcggttcca ttacaggtgc gattgtttcg gctattgttc tgggaatttt
    46621 gaatatgctt ctccaagatg ttgctagtgt gcgtatgatt atttacgctt tggccttggt
    46681 attggtaatg attttcagac caggtggact ccttggaacg tgggagctga gcctatcacg
    46741 tttctttaaa aaatctaaga aggaggaaca aaactaatgg cattacttga agtaaaacag
    46801 ttaaccaaac attttggtgg tctaacagct gttggagatg tgactcttga attgaacgaa
    46861 ggggaactgg ttggattaat cggtccaaac ggagctggga aaaccaccct tttcaacctt
    46921 ttgaccggtg tttatgaacc aagcgaggga acagtaaccc tagatggtca ccttttgaat
    46981 gggaaatcac cttataagat tgcctctttg ggacttggac gtactttcca aaatatccgt
    47041 ctctttaaag atttaacagt tttagataat gttttgattg cttttggaaa ccatcacaaa
    47101 cagcatgttt ttactagttt cttacgctta ccagcttttt acaagagtga aaaagaatta
    47161 aaggataaag ctttggaatt gttgaaaatc tttgatttag atggtgatgc agagactctt
    47221 gctaaaaatc tttcctacgg acaacaacgt cgtttggaaa ttgttcgtgc ccttgctacg
    47281 gaacctaaaa ttctcttctt agatgaacca gcagcaggta tgaacccaca ggaaacagcc
    47341 gaattgactg agttaattcg tcgtatcaaa gatgaattta agattacaat catgttgatt
    47401 gaacacgata tgaatctggt catggaagta acagaacgta tctacgtact tgaatatggc
    47461 cgtttaattg ctcaaggaac tccagacgaa attaagacca ataaacgcgt tatcgaagct
    47521 tatctaggag gtgaagccta atgtctatgt taaaagttga aaatctttct gtgcattacg
    47581 gtatgatcca agcagtccgt gatgtaagct ttgaagttaa tgaaggagaa gttgtttccc
    47641 ttatcggtgc caacggtgca ggtaagacaa ctattcttcg caccttgtca ggtttggttc
    47701 gaccaagttc aggaaagatt gaatttttag gtcaagaaat ccaaaaaatg ccagctcaga
    47761 aaattgtggc aggtggtctt tcacaagttc cagaaggacg ccacgtcttt cctggcttga
    47821 ctgttatgga aaatcttgaa atgggagctt tcttaaagaa aaatcgtgaa gaaaatcaag
    47881 ctaacttgaa gaaggttttc tcacgctttc ctcgtcttga agaacgtaag aaccaagatg
    47941 cagctactct ttcaggaggg gaacaacaaa tgcttgccat gggacgcgct cttatgtcaa
    48001 caccaaaact tcttctttta gatgaaccat caatgggact tgccccaatc ttcatccaag
    48061 agatttttga tatcattcaa gatattcaga agcaaggaac aaccgtcctc ttgattgaac
    48121 aaaatgccaa taaagcactt gcaatctctg accgaggata tgtactggaa acagggaaaa
    48181 tcgtcctatc aggaacagga aaagaactcg cctcatcaga agaagtcaga aaagcatatc
    48241 taggtggcta aaacaatcca gtggattgtt ttagtcggca gatgaagatt acgaagtaat
    48301 catcaatata gtccggggga cctttttagt cggtaaattg agattgcaaa caaatatgca
    48361 tctacattga aagcttaatt tctaataatt gaaaaaatcg aatgaaaagt ttcttacctt
    48421 cattcacaga gctcgatttc agagctcttt ttgctagctt attcatactt ttttgaattt
    48481 cgaaaaagaa atgtaagcgt ttgatagatt tacaaaaaga ttgtataata gggataagaa
    48541 tagaaaagga gaagtttcat ggcagttaaa gattttatga cccgcaaggt agtttatatt
    48601 agtccagata caacagtatc tcatgcagca gatttgatga gagagcaagg tttgcaccgt
    48661 ctgcctgtta tcgaaaatga tcaattagtt ggtttggtga ctgagggaac cattgcacaa
    48721 gcaagtccat ctaaagcaac aagtctttct atctatgaga tgaattatct tctgaataag
    48781 acaaaagtaa aagatgtcat gattcgcgat gttgtcactg tctcaggcta tgctagtcta
    48841 gaagatgcaa cttatctgat gttgaaaaat aagattggta ttctccctgt cgtagataac
    48901 catcaagtat acggagttat tactgaccgt gacgttttcc aagcctttct tgaaattgca
    48961 ggttatggcg aagaagggat tcgtgtacgc tttgttacag aagatgaagt tggtgttctt
    49021 ggaaaaattg tttctttgat tgtagaagaa aatttgaata tctcccatac agtcaatatt
    49081 ccgcgtaagg atggtaaggt gattatcgaa gtgcaaatcg atggatcaat tgatttacca
    49141 gccttgaaag aaaaatttga agcaaatggt attcaagtgg aagaaatcgc tcgcacttca
    49201 gcaaaagtct tgtaagaagg gaagcccaaa ggcttctttt ttcatgaaaa ggggattaga
    49261 gcaaaagatg gaaagaaatg ataaaatatg ctataatgaa ataatgtaaa aaaggagtat
    49321 ttatggacat ttcagtaatt cgtcagaaaa ttgacgcaaa tcgtgaaaaa ttagcttctt
    49381 tcagggggtc tctttgacct cgaagggcta gaggaagaga ttgccatctt ggaaaacaag
    49441 atgacagaac ctgatttttg gaacgataat attgcggccc aaaaaacgtc gcaagaattg
    49501 aatgaattaa aaaacactta caataccttc cataagatgg aagagttgca ggatgaagtc
    49561 gaaattttat tggatttttt ggctgaagac gagtcagtgc atgatgaact ggtagcgcag
    49621 ttagccgaac ttgataagat aatgaccagc tacgagatga ctctactctt gtcagaacct
    49681 tatgaccaca acaatgccat cttggaaatc catccaggtt ctggtggtac tgaggcgcag
    49741 gactggggtg atatgttgct tcgtatgtat actcgttatg gtaatgctaa aggctttaaa
    49801 gtggaagtgt tggattacca agcaggtgat gaggctggta ttaagtcggt aactttatca
    49861 tttgaagggc ctaatgccta tggtctcctc aagtcagaaa tgggtgttca ccgcttagtg
    49921 cgaatctcac catttgactc tgccaaacgt cgccatacct ctttcacatc tgtagaagtg
    49981 atgccagaat tggatgatac tattgaagtg gaaatccgtg aagatgatat caagatggat
    50041 accttccgtt caggtggtgc cggtggacaa aacgtcaata aggtttcaac aggtgtacgt
    50101 ttaacccaca ttccaactgg aattgttgtc caatcaacag tggatcgtac ccagtatgga
    50161 aatagagatc gtgccatgaa gatgttgcag gctaagctct atcaaatgga gcaagataag
    50221 aaggctgcgg aagtagattc tctcaaaggt gagaaaaagg agatcacttg gggaagccaa
    50281 atccgttctt atgtcttcac gccttatact atggtaaaag atcaccgaac tagctttgag
    50341 gttgctcagg tagataaggt tatggatggg gacctagatg gttttatcga tgcttatctc
    50401 aagtggcgaa ttagctaaga tagaaaggaa ctcacatgtc aattattgaa atgagagatg
    50461 tcgttaaaaa atacgacaac ggaacaactg ctctacgcgg tgtttcggtt agcgttcaac
    50521 cgggggaatt tgcttacatc gtaggacctt caggagcagg gaagtcaact tttattcgtt
    50581 ctctgtatcg tgaagtaaaa atcgataaag gaagcctatc agttgctggt tttaatctgg
    50641 ttaagatcaa aaagaaagat gtcccgcttc tacgtcgtag tgttggggtt gtcttccagg
    50701 attataaatt gttaccaaag aaaactgtct atgaaaatat tgcttacgct atggaagtaa
    50761 tcggggaaaa tcgccgtaat atcaaaagac gagtgatgga agttttggac ttggttggat
    50821 tgaagcataa ggttcgttct ttcccaaatg aactctcagg tggggagcaa cagcggattg
    50881 cgattgcgcg tgcaattgta aataatccca aagtattgat agctgatgag ccaacaggaa
    50941 atctggatcc ggataattca tgggaaatta tgaatctctt ggaacggatt aacctacaag
    51001 gaacaactat tttgatggcg actcataata gccagattgt aaataccttg cgccaccgtg
    51061 tcattgccat tgaaaatggc cgtgtcgttc gtgacgaatc aaaaggagag tatggatacg
    51121 atgattagta gattttttcg ccatttattt gaagccttaa aaagtttgaa acgaaatggt
    51181 tggatgacag tagctgctgt cagttcagtc atgattactt tgaccttggt ggcaatattt
    51241 gcatctgtta ttttcaatac agcgaaacta gctacagata ttgaaaataa tgtccgtgta
    51301 gtagtttata tccgaaagga tgtggaagat aatagtcaga caattgaaaa agaaggtcaa
    51361 actgttacaa ataatgacta ccacaaggta tatgattctt tgaagaacat gtctacggtt
    51421 aaaagtgtta ccttttcaag taaagaagaa caatatgaaa aattaaccga gataatggga
    51481 gataactgga aaatctttga aggagatgcc aatcctctct atgatgccta tattgtagag
    51541 gcaaacactc caaatgatgt aaaaactata gccgaagatg ctaaaaaaat tgaaggtgtc
    51601 tctgaggttc aagatggcgg tgccaataca gaaagactct tcaagttagc ttcatttatc
    51661 cgtgtttggg gactagggat tgctgctttg ttaattttta tcgcagtttt tttgatttca
    51721 aataccattc gtattaccat tatttcccgc agtcgcgaaa ttcaaatcat gcgcttggtc
    51781 ggagctaaaa acagttatat ccgtggaccg ttcttgttag aaggagcctt tatcggttta
    51841 ttgggagcta tcgcaccatc tgttttggtc tttattgttt atcaaattgt ttatcaatct
    51901 gtcaacaaat cgttggtagg gcaaaatcta tccatgatta gtccagattt atttagtccg
    51961 ttgatgattg ccctactatt tgtgattggg gttttcattg gttcattggg atcaggaata
    52021 tccatgcgcc gattcttgaa gatttaggta aaatagctgc ttttatgagg agattgtaaa
    52081 atctcctttt ttgctacaag agtttttgaa aagagatgcg cagaagaaaa gagcttccaa
    52141 agaagtcccc cagagaagac ttcttgatgg ctaatttgaa cttgaaattt gactcactag
    52201 aaatttttta gaaaaaagtg taattttttt ataaaagcct ttacaaaaaa aattaaagtg
    52261 gtataattaa atcatagaaa gtgcaaacgt tttcgtaaaa cgtttgccta aataaaaata
    52321 aaggagattt gaatgatgaa agatacattc aaaaatgtct tgtctttcga attttggcaa
    52381 aaattcggta aggctttgat ggtagttatc gcggttatgc cggctgctgg tttgatgatt
    52441 tcaatcggta agtctatcgt gatgattaac ccaacctttg caccacttgt catcacaggt
    52501 ggaattcttg agcaaatcgg ttggggggtt atcggtaacc ttcacatttt gtttgcccta
    52561 gccattggag gaagctgggc taaagaacgt gctggtggtg ctttcgccgc tggtcttgcc
    52621 ttcatcttga ttaaccgtat cactggtaca atctttggtg tatcaggcga tatgttgaaa
    52681 aatccagatg ctatggtaac tactttcttt ggtggttcaa tcaaagttgc tgattacttt
    52741 atcagtgttc ttgaagctcc agccttgaac atgggggtat tcgtagggat tatctcaggt
    52801 tttgtagggg caactgctta caacaaatac tacaacttcc gtaaacttcc tgatgcactt
    52861 tcattcttca acgggaaacg tttcgtacca tttgtagtta ttcttcgttc agcaatcgct
    52921 gcaattctac ttgctgcttt ctggccagta gttcaaacag gtatcaataa cttcggtatc
    52981 tggattgcca actcacaaga aactgctcca attcttgcac cattcttgta tggtactttg
    53041 gaacgtttgc tcttgccatt tggtcttcac cacatgttga ctatcccaat gaactacaca
    53101 gctcttggtg gtacttatga cattttaact ggtgcagcta aaggtactca agtattcggt
    53161 caagacccac tatggcttgc atgggtaaca gaccttgtaa accttaaagg tactgatgct
    53221 agtcaatatc aacacttgtt agatacagta catccagctc gtttcaaagt tggacaaatg
    53281 atcggttcat tcggtatctt gatgggtgtg attgttgcta tctaccgtaa tgttgatgct
    53341 gacaagaaac ataaatacaa aggtatgatg attgcaacag ctcttgcaac attcttgaca
    53401 ggggttactg aaccaatcga atacatgttc atgttcatcg caacacctat gtatcttgtt
    53461 tactcacttg ttcaaggtgc tgccttcgct atggctgacg tcgtaaacct acgtatgcac
    53521 tcattcggtt caatcgagtt cttgactcgt acacctattg caatcagtgc tggtattggt
    53581 atggatatcg ttaacttcgt ttgggtaact gttctctttg ctgtaatcat gtactttatc
    53641 gcaaacttca tgattcaaaa attcaactac gcaactccag ggcgcaacgg aaactacgaa
    53701 actgctgaag gttcagaaga aaccagcagt gaagtgaaag ttgcagcagg ctctcaagct
    53761 gtaaacatta tcaaccttct tggtggacgt gtaaacatcg ttgatgttga cgcatgtatg
    53821 actcgtcttc gtgtaactgt taaagatgca gataaagtag gaaatgcaga gcaatggaaa
    53881 gcagaaggag ctatgggtct tgtcatgaaa ggacaagggg ttcaagctat ctacggtcca
    53941 aaagctgaca ttttgaaatc tgatatccaa gatatccttg attcaggtga aatcattcct
    54001 gaaactcttc caagccaaat gactgaagca caacaaaaca ctgttcactt caaagatctt
    54061 actgaggaag tttactcagt agcagacggt caagttgttg ctttggaaca agtaaaggat
    54121 ccagtatttg ctcaaaaaat gatgggtgat ggatttgcag tagaacctgc aaatggaaac
    54181 attgtatctc cagtttcagg tactgtatca agcatcttcc caacaaaaca tgcttttggt
    54241 attgtgacgg aagcaggtct tgaagtattg gttcacattg gtttggacac agtaagtctt
    54301 gaaggtaaac catttacagt tcatgttgct gaaggacaaa aagttacagc aggagatctc
    54361 cttgtcacag ctgacttgga tgctatccgt gcagcaggac gtgaaacttc aacagtagtt
    54421 gtcttcacaa atggtgatgc aattaaatca gttaaattag aaaaaacagg ttctcttgca
    54481 gctaaaacag cagttgctaa agtagaattg taatatactt gaggttggaa gctgtattcc
    54541 aacctcttat tttgggagaa aagaatgaaa tttttaacac tcaatactca cagttggatg
    54601 gagaaagaag cagaggaaaa attccagatt ttgcttgaag atattcttga aaaggactat
    54661 gatttgattt gtttccaaga aatcaatcag gagatgacct cgtcagaggt ggaggttaat
    54721 gacctttatc aagctttgcc agcagctgag cctattcacc aagaccatta tgttagactc
    54781 ttggttgaaa agttgttaga gcaagggaaa aattactact ggacctgggc ttataaccat
    54841 atcggctatg accgctacca tgaaggtgtg gctatcttgt ctaaaacacc tattgaagcc
    54901 agagaaattt tggtttcaga tgtggatgat ccaacagact atcatactcg ccgtgttgcc
    54961 ctagctgaaa ctgtagtcga tggcaaggag ctagcagttg ccagtgttca tctctcttgg
    55021 tgggataaag gtttccaaga agaatgggca cgatttgagg ctgtcttgaa aaaattgaac
    55081 aagccacttt tactagctgg agattttaac aacccagcag gtcaggaagg ttaccaagct
    55141 attttagcta gtccattagg cttacaagac gcatttgaag ttgctcaaga gaaaagtggt
    55201 agctatactg ttccgcctga aattgatggc tggaaaggga acactgaacc ccttcgaatc
    55261 gattatgtct ttactaccaa agagttagcg gtggaaaatt tacatgtcgt atttgatggt
    55321 aacaagagtc cacaagtgag tgatcactat ggcttgaatg cggtattaaa ttggaaataa
    55381 aatcaaaaaa tgaaagggag cgagtccttt cattttttta caaaaatccc tataattact
    55441 attttggaga aggagttttt tgtatatttg tatattatga ggaaatatcc acaaataagt
    55501 ttttaaaact ttacggtcaa aaaaaatcgc taatattaac tatttatgat agaatgaaaa
    55561 ttatgaaata aaaggaggac tggaatgttt tttcaggata gaaagataaa atattcaatc
    55621 cgcaaattgt cagttgctac tgtgtccctt gcgattggat ttttgtttgc gcctgcggcg
    55681 cttggagtcg ctcaagtagc tcaagctgat gagctttcaa ctactgaaca agtggagaat
    55741 aaagcagaga atcaggtctc ggtggtctct tttgcaacag agcaagaaga aagtgaaacg
    55801 acttatgttg atacgacgaa taaagtgact tggacatttg caggatacga taaagaaaaa
    55861 attgttgtag gaaaaggcag acagactttc cttggaagct gggtacctac tccaaatcca
    55921 gaatatgtat tcaaatcatc taaagcaggt gttccattac cacaaagtat tttgggaatg
    55981 cttccaaagg atgaagcttc ttataaggtt ggtgacacca ttgtagccaa acaacctgct
    56041 gtagaatcag tagtcgaaga agaaaaagac tatgtctgga ccttcaaagg ttatgatcag
    56101 aagaatgcga cgtacaatgg caagcgtgtg acatttacag gtatctggga agtaacgcct
    56161 agaccgcatc atgtaagcta tacttttgta agtgttacat ctggtgttga tttgcctaaa
    56221 tttatccaga agaaagcacc aaaagatggc tcaacttact tcaataggac gagagttttt
    56281 gcagaagagc cgacaacaaa gacctacata gatagtgtga acgatggcac atggaccttc
    56341 aagggttatg acgcagctag cgccgttgtt aacaaggcta atgtagagtt tgtaggtaag
    56401 tgggaattca aggcgaatcc gacaaatgcg gaaacttata cgcctcaggt aacggaagaa
    56461 actatcaagg ttggacaaac acctgacttg accgataatg tgacgaactt gccaaacctt
    56521 ccagctggca ctaaggtagt tgatattaca cctgcaggtc aaattgacac aacaaaacca
    56581 ggtacttaca caggtaaggt gcgagttgac tatccagatg gttcttctac tgaggtgtct
    56641 gtatcagtta atgttttgcc tgcaccagaa actcaaacct ataaggtgac ttaccgcttc
    56701 gaaagtgcaa ccgcagacaa caacttgcca gcagaagtat tgagcttact cccacaaagt
    56761 ggaacatata ctacaagttc ttctgtagcg attgctttcg ttccagaagc accgatgcct
    56821 gtagaagttg ctgttgcaaa tggtacatgg acattcttag gttaccaaga agtggaagag
    56881 gggtcaaatc taaccttcgt cggtaagtgg gtctttgaag ctaagcaaga tcctagtcca
    56941 caaccacagc cggcaccaac gccacaacca gcacctcaac caaatccagt tccaccagtg
    57001 aatccagggg gagagcaggg aactgataat aatcaggcag atagacatca atcagaacaa
    57061 ccaagaaaac ctgaagagaa tccaccagct caaggtccag caggagaaaa ggaaaaacaa
    57121 gctacattgc caaatgcggg tagtactgca ccactttcac tcactggact agtgactagc
    57181 tctcttcttg caggtctagc agtgttgctt cttggtcgca agcggaaaga tgattaagta
    57241 ctaatttttc tagaagcttt cgacttttac aagattctta agcaactgtt tgactgtttg
    57301 acaaatctat ctgagtcgca agctttaagg ctgagagaag accaatttgg tcttctcttt
    57361 ttgcattttg gaaagaaagc aaatgtatga tttttagtat aagagaggta tagtagattg
    57421 aaactagaat agtacacctc tgcttctaaa acattgttag aaatcgattt gactgtcctg
    57481 atcgattcat cctattctta tttcatttta ctatatttag agaaattgag agccttgtga
    57541 taggtcagat gagtcggact actgaaaatg ttcaaaatat ggtataattg ataagataga
    57601 tagaatcgag gatgttatgt catttacgaa atttcaattt aaaaactata ttagagaagc
    57661 cttgaaggag ttaaaattta caactccaac agaggtgcaa gacaagttga ttcctattgt
    57721 tttggcaggt cgtgacctag taggagaatc aaaaacaggt tcaggtaaga ctcatacttt
    57781 cttgttaccg attttccagc aattagatga agctagcgat agtgtgcaag cagtgattac
    57841 tgcaccgagt cgtgagttgg ctactcaaat ttaccaagta gcgcgtcaga tttcagctca
    57901 ctcagatgtc gaagttcgtg tggttaatta tgtgggtggt acggataagg ctcgccagat
    57961 tgagaaattg gcaagcaatc agcctcatat tgttattgga acaccaggcc gtatctacga
    58021 cttggttaaa tctggtgatt tagctattca taaagccaag acatttgttg ttgatgaagc
    58081 agatatgacc ttggatatgg gattcttgga aactgttgat aagattgctg gcagtcttcc
    58141 aaaagacttg caattcatgg tcttctcagc gactatccca caaaaactgc aaccattctt
    58201 gaaaaaatac ttatccaatc ctgttatgga gaaaattaag accaaaacgg ttatttctga
    58261 caccattgat aattggttga tttcgaccaa gggacatgat aagaatgctc aaatttacca
    58321 gttgactcag ttgatgcagc cgtatttggc aatgattttt gttaacacta aaacgcgtgc
    58381 tgatgaattg cattcatatc tgactgctca aggcttgaag gttgcaaaaa tccatggaga
    58441 tattgcccct cgtgaacgca agcgaatcat gaatcaggtg caaaatctgg attttgagta
    58501 tattgtcgca acagatttag cagcgcgtgg gattgacatt gaaggtgtca gccatgtcat
    58561 caatgatgcc attccgcaag acttatcttt ttttgttcac cgtgttggtc gtactggacg
    58621 aaatggccta ccaggtacag ctattaccct ttatcagcca agtgatgact cggatatccg
    58681 tgagttggag aaattgggaa tcaagtttag tcctaagatg gtcaaagacg gggaatttca
    58741 agatacctat gaccgtgatc gtcgtgccaa ccgtgagaaa aaacaagata aacttgatat
    58801 cgaaatgatt ggtttggtta aaaagaaaaa gaaaaaagtc aaaccgggtt ataagaagaa
    58861 aattcaatgg gcggttgatg aaaagcgccg taaaaccaag cgtgctgaaa atcgcgctcg
    58921 cggtcgtgca gagcgtaaag ctaaacgcca aacattttaa tagaaattgt tggagtactg
    58981 agctccaact ttttgcttta tgagaacgaa ctatctaaac cgaaacacta cattaaagac
    59041 tgcaaattgc gattaaaaat ggtataatga taaagttata tagtcccgat aagatggtag
    59101 gtatttatta cgaagagttt tcctatcagt agtttgcaat tcgcaaagaa tgacggcttc
    59161 gaggttgctc gtctttctac ggttgccgcc atactgcggt caccctatgc gccttactag
    59221 cttcagaaat aaaaacgata cttttttatt tctgaagcta gtaactctta gataatggaa
    59281 attcctatca gtactttgta actctataac aatatttttt aaggggggac atttttatgt
    59341 cagaacgtaa attattcacg tctgaatctg tatctgaggg gcatccggat aagattgcag
    59401 accaaatttc agatgcgatt ttggatgcta ttttagcaaa ggatccagag gcgcacgttg
    59461 ctgctgaaac agctgtatat actggttctg tccacgtttt tggtgaaatt tctacaaatg
    59521 cctatgtgga tattaaccgt gtggttcgtg ataccattgc agagattggt tataccaata
    59581 cagaatatgg attttctgct gagacggtgg gagtacaccc atctttggtg gaacaatctc
    59641 ctgacatcgc tcaaggtgtt aacgaagcct tggaggttcg tggaaatgct gatcaagatc
    59701 cactggactt gattggagca ggtgaccaag ggctcatgtt tggatttgca gtagatgaaa
    59761 cagaagagct catgccattg ccaattgcac tcagtcataa attggttcgt cgtctggcag
    59821 aacttcgtaa gtctggagaa attagctatc tccgtccaga tgcaaaatca caagttacag
    59881 ttgagtacga tgaaaatgac cgtccggtac gtgtagatac agtcgttatt tctactcagc
    59941 atgatccaga ggccactaat gaacaaatcc atcaagatgt gattgacaag gtcatcaaag
    60001 aagttattcc atcttcttat cttgatgata agacaaaatt ctttatcaat ccgacaggtc
    60061 gttttgtaat cggtggtcct caaggggact caggtttgac tggtcgtaag attattgtag
    60121 atacttatgg tggctactct cgtcatggtg gtggtgcctt ctctggtaaa gatgcgacta
    60181 aggtggatcg ttcagcctct tatgcggctc gctatattgc caagaatatc gttgcagcag
    60241 gccttgctaa gaaggcagaa gtgcagttgg cctatgctat cggtgttgcg caacctgttt
    60301 ctgttcgtat cgatactttc ggtacaggaa cagtagctga aagtcaactt gaaaaagcgg
    60361 ctcgtcaaat ctttgacctt cgccctgcag ggattatcca aatgctggac ctcaagcgtc
    60421 caatttaccg tcaaacatcg gcttacggtc acatgggacg tacagatatt gatcttccat
    60481 gggaacgttt ggataaggta gatgctttga aagaagcagt aaaataagat tttaagaggg
    60541 gaacgtcctc tcttttttat agtttttaac tatactggga tactgttctg aaaatccatt
    60601 ttgcgaaagt agagatttac atgtatagta gattgaaact agaatagtac acctcaactt
    60661 ctaaaacatt gttaaaaatc gatttgactg tcctgatcga tttctcctgt tcttgtttca
    60721 ttttactata tttctttaaa aatgataaag gttaagattt ctcctcgtaa tagataatct
    60781 tggggatatt tcaatccaaa gttttattcg ttatcacttg actattgcaa ggttttctag
    60841 agcaacagag tcatggaatg gactcatggt tgagatttct ccttgttgct tggacttcat
    60901 tcaaaagtct gttacccaag ccttgttcaa acttctaata cactagctgt ttccatagca
    60961 tgacttctgt actagacttt cttttccgaa taaatagata gaaccacaga atctagtaaa
    61021 cctagaatta aaattatggt ataatattag caataaaaga aatctggagg attagaatca
    61081 tggtatcaac gaaaacacaa attgctggtt ttgagtttga caattgcttg atgaatgcag
    61141 caggtgtggc ttgtatgacg atagaggagt tagaagaggt caaaaactca gcggcaggaa
    61201 cctttgttac taagacagcg accttggact tccgtcaggg gaatcctgag ccacgctacc
    61261 aagatgttcc acttggttcc atcaactcta tgggcttgcc aaataatggc ttagactatt
    61321 atttggatta tcttttagat ttgcaggaaa aagagtcgaa ccgaactttc ttcttatctc
    61381 tggtcggcat gtctccagag gaaacccata ctattttgaa aaaagtccaa gagagtgatt
    61441 ttcgtggtct gactgagcta aatctttcct gtccaaatgt tccaggtaaa cctcagattg
    61501 cctatgattt tgagacaaca gaccggattt tggcagaagt gtttgcttac ttcaccaaac
    61561 ctcttggaat taaattgcca ccttattttg atattgttca ctttgatcaa gcggcagcta
    61621 ttttcaacaa atatccgctc aagtttgtca actgcgttaa ctctatcgga aacggcctct
    61681 atatagaaga cgaatctgtc gttattcggc ctaagaatgg ttttggtgga attggtggag
    61741 aatacatcaa accgactgct ctagccaatg ttcacgcctt ttatcaacgt ttaaatcctc
    61801 aaatccaaat tatcggaaca ggtggcgttc tgactggtcg agatgccttt gaacacatcc
    61861 tctgtggagc aagtatggtg caggtgggaa cgacccttca caaagaaggc gtcagtgctt
    61921 ttgaccgcat taccaatgaa ctgaaagcaa tcatggtgga aaaaggctac gagagcttag
    61981 aagatttccg tgggaaattg cgctatattg actaaattaa atcgaaaaat ctgaagaaag
    62041 gagagacgat gctagccatt gaagaaagtc agaagttgac tttatcaaat ttaccgagcc
    62101 tgagcctatt tacagggaca gatcagggtc agtttgaagt gatgaagagt caagtgttga
    62161 aacagattgg gtatgattct gctgacctca actttgccta ctttgatatg aaagaagtag
    62221 tttacaagga tgtggaactg gagttggtca gccttccttt ctttgcggat gagaaaatcg
    62281 tgatattaga ttattttatg gatatcacga ctgctaagaa acgctttttg acagatgatg
    62341 agcttaagtc atttgaggaa taccttgaca atccttctcc aacaaccaag ttgataatct
    62401 ttgcagaagg aaagctggat agcaaaagac ggttagtcaa attacttaag cgtgatgcca
    62461 aggtcttcga tgcagtagaa gtaaaagaac aagaattgcg ccagtatttc caaaagtgga
    62521 gtcagaaaca aggtctgcag tttaccaatc attcttttga aaatctcctc atcaagtcgg
    62581 ggtttcaatt tagcgaaatc cagaaaaatc ttctcttttt acagtcctat aaggcgaatt
    62641 ctgttatcga ggaagaggat attgttaacg caattcccaa gaccttgcag gacaatattt
    62701 ttgatttaac tcagtttatt ctgactaaaa agatggatca ggcgcgcgat ttggtgagag
    62761 acttgacctt gcaaggggaa gatgaaatca aactgattgc agtcatgctg ggacaatttc
    62821 ggacttttac tcaggtgaag attttggcgg agtctggcca aacagaatcg cagattgcaa
    62881 gtagtttagg tagttatctg ggacgtaacc caaatcctta tcaaatcaag tttgcattaa
    62941 gagattcgag aggactttct ttgagctttc tgaagcaagc tatttcctat ttgattgaga
    63001 cagactatca gattaagaca ggtctttatg aaaaaggttt cctttttgaa aaggcactct
    63061 tacagattgc tagtcaggtc aattgacatt tgttgaaact acaacccacg tcaggattat
    63121 cttgtcgtgg gtttcttgct gatttgctta tctataagca aaaaacttga aaaaagtgaa
    63181 tgtttgcgtt atcattttca tatagaaaga aaaagaggta ttacagatgg ctattatctt
    63241 accagaactt ccatatgcat acgacgcttt ggaaccatac atcgatgcgg aaacaatgca
    63301 tttgcaccat gacaaacacc atcaaactta tgtcaacaat gccaatgcag ctttagaaaa
    63361 acaccctgaa atcggtgaag accttgaagc cttgcttgct gatgtagaat ctatcccagc
    63421 tgatatccgt caagcactta tcaacaatgg tggcggacac ttgaaccacg ctcttttctg
    63481 ggaattgatg actcccgaga aaacagctcc ttcagcagaa ctggcagcag caatcgatgc
    63541 aacatttggt tcatttgaag aattccaagc agccttcact gcagcagcaa caactcgttt
    63601 tggttcaggt tgggcatggt tggttgtcaa caaagaaggg aaacttgaag tgacttcaac
    63661 agcaaaccaa gacacaccaa tctcagaagg taaaaaacca atcttgggct tggacgtttg
    63721 ggaacatgct tactacgtga aataccgcaa cgtgcgtcct gactacatca aagctttctt
    63781 ttcagtaatc aactggaata aagtagatga attgtacgca gctgctaaat aatgatagtt
    63841 ggagggaaga attgttcttc tcttttttag gttataagat tctggtctga caaaatcgtt
    63901 agactttttt catttttatg agaaacgtgc taactgctag aaattatggt agaataaagt
    63961 attaagtaat cgtggaaaaa ggatatctat gcgaaaagaa attgcacctg aattatacaa
    64021 ctataacaag tttcctggtc cggagttcca tttacacggg gataaggtcg aaacggaagg
    64081 gatagctttt tccttggttg aaaatatcaa ggatgccttt gatgtgacga cttttaatca
    64141 gcgtttttca gaagtcttaa ccaagtttga ttatatcgtg ggggactgga gcaacgaaca
    64201 gcttcgccta cgaggttttt acaaggatga ccgaacagaa gaaaaacttg aaaaaatcag
    64261 tcgtttacaa gactaccttt tagagtattg tagttatggt tgtgcctatt ttgtcttaga
    64321 aaatgaagcc cctaagcgag catcatttga caagaaaatg cgtaagacgg aagaagaaac
    64381 accttctaga aaaggaaaga aaccgactca aactaaacga aagtcgaatg cagataagaa
    64441 gaatagacgt cgtcagaaag accagcattc tcagaaagag gacaagggac aacgtcattt
    64501 tgtcattcgt cagaagtgag tagagaataa ggagaagaaa tgaaaccttc aattcatagt
    64561 ttgacacatc aaaccatgca ggaatgggta ttggagcagg gagaaaagaa attccgtgca
    64621 gatcaaatct gggaatggct ctaccgtaaa cgtgtgcagt catttgaaga aatgaccaac
    64681 ctttccaagg atttgattgc taagctcaat gaccagtttg tggtcaatcc cttgaaacaa
    64741 ggtattgtgc aagagtctgc tgatggtaca gtcaaatatc tctttgaatt gcctgacggt
    64801 atgttaattg agactgtact catgcgtcaa cactatggtt tatctgtctg tgtgaccact
    64861 caggtcggct gtaatatcgg ttgtaccttc tgtgcctctg gtttgattaa gaagcaacgt
    64921 gacctcaata acggtgaaat cgtagcgcaa atcatgctgg ttcagaaata ctttgctgag
    64981 cgtggtcagg atgaacgcgt caaccatatc gttgtcatgg gaatcggtga gccctttgat
    65041 aattacaaca atgtcttgaa tttctttcgt actatcaatg atgataaagg aatggctatc
    65101 ggtgctcgtc acatcacggt ttcaacctca ggtttggctc ataaaattcg tgactttgct
    65161 gatgaagggg ttcaggtcaa tcttgccgtg tctcttcacg cacccaacaa tgaacttcgt
    65221 tcaagtatca tgaagcttaa ccgtgccttt ccgattgaaa aactctttgc tgctattgaa
    65281 tactacattg agacaacaaa ccgtggtgta acctttgaat atatcatgct taatgaagtc
    65341 aacgacggtg tagaacaagc cttggaattg actgaattgc tcaagaacat caagaaattg
    65401 tcttatgtaa acttgattcc ttataaccca gttagtgagc atgaccaata tagccgtagt
    65461 cccaaagagc gcgtgttggc tttctatgat acgcttaaga aaaaaggggt caactgtgtg
    65521 gttcgtcaag agcatggtac agatattgac gcagcttgtg gacaattgcg ctctaacaca
    65581 atgaaacgtg accgccagaa ggcagtcgca gcggtaaatc cttaatgatg aagaagactt
    65641 ataatcatat tttggtctgg ggagtcattt tctatagcat ttgcattgtc tatttttgct
    65701 ttactcctca agaacaatct accgtgggag tgggaactcc agatattcag catcttggac
    65761 gcctggtttt tcttttgact cctttcaatt ctctctggaa actgggcgaa gtgagtgaca
    65821 ttggacaatt atgttggatt tttttacaaa atatcctcaa tgtcttcttg ttttttcctc
    65881 tgattttcca actcctttat ctatttccaa atttgcggaa aacaaaaaag gtccttcttt
    65941 ttagttttct tgtgagtctt ggaatcgagt gtacgcaatt aatcttggac tttttctttg
    66001 atttcaatcg cgtctttgag attgatgatt tgtggaccaa cactttgggt ggctatctgg
    66061 cttggctcct ttataaacga ttacataaaa acaagataag gaattaaaat gagtatttta
    66121 gaagttaaaa atctgagtca cggttttggt gaccgtgcaa tttttgaaga tgtgtccttc
    66181 cgtctcctca agggagaaca tatcggcctg gtcggtgcca atggtgaagg aaaatcaacc
    66241 tttatgagta tcgtgactgg taaaatgctg ccagatgaag gaaaggttga gtggtccaaa
    66301 tatgtgacgg ctggttactt ggatcagcac tctgtccttg ctgaaagaca gtcggtgcgt
    66361 gatgttctcc gtacggcttt tgatgagctt ttcaaagctg aagctcgtat caatgacctc
    66421 tatatggaaa tggctgaaga cggtgcggat gttgatgctc tcatggaaga agtaggagaa
    66481 cttcaagacc gtctggagag tcgtgatttc tataccttgg atgctaagat tgacgaagta
    66541 gcgcgtgctc ttggtgttat ggactttggc atggatacgg atgtaacttc tttgtcaggt
    66601 gggcaaagaa ccaaggtgct tttggcaaaa cttctccttg aaaagcctga tatcttgctg
    66661 ttggacgagc cgaccaacta cttggatgct gagcatattg attggctcaa gcgctatctc
    66721 caaaactatg agaatgcctt tgttctcatt tcgcacgata ttccattcct caatgacgtt
    66781 atcaatattg tctatcatgt ggaaaatcaa cagctgacgc gttactctgg tgactactac
    66841 cagttccaag aagtttatgc tatgaagaaa tctcagctag aggcagccta cgaacgccag
    66901 cagaaagaga ttgcagacct caaggacttt gtggctcgta ataaagcccg tgttgcaact
    66961 cgtaatatgg ctatgtctcg tcaaaagaaa ttggataaga tggatattat cgaactccaa
    67021 agtgagaaac caaaaccatc ctttgatttc aaaccagctc gtacaccagg gcgctttatc
    67081 ttccaagcca agaacttgca aattggttac gaccgtcctc ttactaagcc tttaaatctt
    67141 accttcgaac gcaatcaaaa ggttgcgatt attggtgcta atggtattgg aaaaacaact
    67201 ctcttgaaga gtctcttagg cattatctcg ccaatcgctg gggaagtgga gcgtggagat
    67261 tatttagaac ttggttattt tgagcaggaa gtagaaggcg gtaatcgcca aactcctctt
    67321 gaagctgtct ggaatgcctt tcctgccctt aatcaagcag aagtccgtgc agcccttgcc
    67381 cgttgtggtt tgacaaccaa acatattgaa agccagattc aagtattatc agggggagag
    67441 caagccaagg ttcgtttctg tctcttgatg aatcgtgaaa acaacgtttt agtgctggac
    67501 gagccgacca accatttgga tgtggatgca aaggatgagc tcaaacgcgc tctcaaagaa
    67561 tataggggat ctatccttat ggtctgccac gagccagact tttatgaagg ctggatagac
    67621 caaatatggg attttaataa tttaacttaa gaatgagagt aaaagaaata cagtaccgaa
    67681 tgtggatact gtattttttt tggtttttaa gatttaaaat cgtagtcttt caccacttcg
    67741 atgctgtcga ttgtgatagc agtagttggc ttgtcttttt catctttttc ggctttagca
    67801 atcttatcca caacatccat accgccaatc acttgaccaa agactgggtg tttgccatct
    67861 agactagggt ttccaccttc tttgtaggct tcgataattt tctgtggata cttgcttgta
    67921 gggagtttag aagaggtatc tgtagagttt tggttgatga agaactggct gccattggtg
    67981 tttggttgac cagtattagc catagcaaga gcaccgcgga tgttatacaa ataaggagta
    68041 atctcgttct tgaaaccagt tcctttgtct ttagtcttat ccttgtcatg ccagatggac
    68101 tgaccacctg taccgtcccc ttttggatct ccagtttgga ccataaagcc atcgatgaca
    68161 cggtggaagg taataccgtt atagtagcct tctttggcgt gagtgaggaa attttcaacc
    68221 gctagaggag cgagtttagg gaagagttta atgcgaatat caccttggct tgtgtggaga
    68281 atcacttcgg cttcatcttc agcaacttcc ttagatagtt gtgggaaatt ggcgttttcg
    68341 tttgttaaag catcgtttaa ctccttggca gattgggcag ctactttgga actttcttca
    68401 gcagcaagac tggaatcaac ataatcatca ccacgcagac tgcgttggac gctgctacac
    68461 ccagctaggg ctacagtaga cagtaaaaga agggttgcta gttttttcat tctgatcctc
    68521 tcaaaaattc atttataacc attgtaccct aaaaggaagt ggatttcaaa tattagtagt
    68581 ttacagaact ggcttagata atagttggga tttcatcatc atcttgaaaa tcttcaactt
    68641 cttccccagt aaatggtttc tgaaaagaac ttagtataaa acgggcaatt ggttcaacaa
    68701 ttaggaaatt tagaggaaga gctgcaataa agtttacgaa ccaggcgctt agataggtat
    68761 tgggtgtgat agcaatgcca ttgtaaaaaa gtccatagaa ggacatgaaa gtgaccagct
    68821 aattcttctt ctgaaaaatg ctcatgaagg gcttgatcca ggtcgcaaga tttcatttta
    68881 gaaagtccag taactccctt cttcttcagg atattctttt tcatggtagt atttagatgg
    68941 tcaagtgagt caaaagaagt ttcgacaaga gcataccctt tttctaccag agtttttaga
    69001 tgtttagggg catcaatacc ataagtgtac tcaaagtatt ttggaaacca gatcttaaga
    69061 aagctcgtaa agctagccag ttctctaaac gctaagaact agctacaaca cagcatttac
    69121 aacacttcat ggttcacacc atggggtgtt ttttaatgat tttaagcaaa attcacactt
    69181 aattgaaagt tatttaaatt agatgaaaat ttattttttg aaaaagtggg aaaacattga
    69241 ttctaagcga attttgaatc atattcgaat gggagttttt aaaatcatgt ttcagtggta
    69301 aaagtaccaa actggattct ccatagtaaa atgatatctc ctgctagtga atcatctact
    69361 aataagtcca tatttcgctt gggaacgggc ttgggactta gaagccaagt atccaactct
    69421 cgttcaggcg atatgaaggg tttgacttgg tgttctttat aaaatttttc taaaatagta
    69481 ttcacggata gcatctttca aacatttatt tcctattcta acaaatttct aaatacttta
    69541 agaaatttat agtctgtcaa gtttttttct tgacacatgc cagaaatctg ctataataga
    69601 acatgtgcta aatagctcag ctatttcacc gaaataaaaa attaaagaaa tgagacttta
    69661 aaaatggcag ttaaaatccg tttgactcgt atgggttcta agaaaaaacc tttctaccgt
    69721 atcaacgtag cagattcacg ttcaccacgt gacggacgtt tcatcgaaac agttggaact
    69781 tacaacccac ttgttgctga aaaccaagta actttgaaag aagaccgcgt tcttgcatgg
    69841 ttggctaatg gagctcaacc ttcagacaca gtacgtaaca tcctttcaaa agaaggcgta
    69901 ttgaaaaaat tccacgattc taaattctca aaataagttt aaagtaggtt gacagatgga
    69961 tacgattgaa aatctcatta ttgcgattgt gaaaccctta atttcacaac cagatgcctt
    70021 aactatcaag attgaggata caccagaatt tttggaatat catttgaatc ttgatcaaag
    70081 cgatgtgggt cgtgtaatcg gtcgtaaggg tcgcactatt tctgcgataa gaacgattgt
    70141 ctactctgtc ccaactgaat acaaaaaagt aagaatcgtt attgacgaaa aataagaagg
    70201 gcgggacgga tgtctcgctt ttttgtgtgg aatagaagat atagtaaaat gaaacaagaa
    70261 taggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga agtaaaggtg
    70321 tactattcta gtttcaatat actataaaag attgaacgtt taggcaattc caagactact
    70381 taatcgaaca ttaacagcag tctcggactg atgaaggtct ctttatgaag ttagtggagg
    70441 aagtcggaga agtagccgag gttttgaata ggcgctctgg tcgaaaagaa gggataggat
    70501 tcgaacgagg aacttgccag agaactggct gatatcattt actacaccgt cgcaatcgta
    70561 gctattaatc atattgacct taccaagact gtctttgaga aagacaaaac cgcagccgtt
    70621 aattaccaac ataaacataa tttggaagga ttcttgaagg gaaagtagag atattgtccc
    70681 cttcctccaa cttgagaaaa tccttggaac gtgataaaat aaaggataag gatttttaat
    70741 aattcattat atagaatcag tggatttctt tatgaagagg tttgaagtat ctacagaaat
    70801 tggtagcctc tctgttactt atcaaaagca aaagaaagtg ctagtttgtc taaacggagc
    70861 aggtttgcta ccaagttatg aaaatttttc acttatactt gaaaaacctc ctcctacaat
    70921 tggttatttg acaattgatt ttccgaacac aggtaggagt ccgattcatg accaagctgg
    70981 aaaaaatcta gataatcttg cagatgtggt ttatgaagca cttgaagaat taggaatttc
    71041 tgaatatata ctttgtgtac atagttggag tggaatttta gcttgcaaat tactcgagaa
    71101 accaattaag tgtcagactt tagtagcaat tgaaccgaca actaaaaaag tcatgtttgc
    71161 tgatttttca gaaaatcctt atccagaaat ggaagagcag atgaggctga ttgacgagtg
    71221 tggtcctgaa ctttatttta agaacttaac tcaagcaaca tttagtcctg aaacgaataa
    71281 aaaaatctgg gaattaatgc aagaaaaagg cttagagttg gaaaatcaag atccagaatt
    71341 tcagatatct ggagagatta ctgaggaaga ttttgagaat ttgtcgatag aatctcatgt
    71401 ccctgttttt attttttgtc agacttatag agaaaaagag tacagagaat cagaatattg
    71461 gacttccaat actaaactca ttttaggagg gaatcgccat tatttacaat ggtcagaatc
    71521 ggaaaaaatt gcggctatta ttcgagaatt gtcagaataa gatggaaaaa aggagattac
    71581 aggagacaag atgaactact ttaatgttgg gaaaatcgtt aatacgcagg gattacaggg
    71641 tgagatgcga gtcttgtctg tgacggattt tgcagaagaa cggtttaaaa aaggagctga
    71701 gctggctttg tttgatgaaa aagatcagtt tgtccaaaca gtgaccatcg ctagccaccg
    71761 taaacagaag aactttgaca ttattaaatt caaagatatg taccatatca atactatcga
    71821 aaagtacaag ggatacagtc tcaaggtcgc tgaggaagat ttgaatgacc tagacgatgg
    71881 tgaattttac tatcacgaga ttatcggttt ggaagtctat gagggtgata gcttggttgg
    71941 aaccatcaag gaaatcctgc aaccaggtgc taatgatgtc tgggtggtca aacgaaaagg
    72001 caaacgtgat ttgcttttac cttatatccc accagtggtt ctcaatgttg atattccaaa
    72061 taaacgggtc gatgtagaaa tcttagaagg gttagacgat gaagattgat attttaaccc
    72121 tctttccaga gatgttttct ccactggagc actcaatcgt tggaaaggct cgagaaaaag
    72181 ggctcttgga tatccagtat cataattttc gagaaaatgc tgaaaaggcc cgtcatgtag
    72241 atgatgagcc ctacggaggc ggtcagggca tgttgctcag agcacaacct attttcgatt
    72301 cctttgatgc tattgaaaag aaaaatccgc gcgttattct cctcgatcct gctggaaagc
    72361 agtttgatca ggcttatgct gaagatttgg ctcaagagga agagctaatc tttatctgtg
    72421 ggcactatga gggttatgat gagcgcatta agaccttggt aacagatgag atttccctag
    72481 gcgactatgt cctcactggt ggagaattgg cagctatgac catgattgat gctacagttc
    72541 gcctgattcc agaagtgatt ggcaaggaat ctagccacca agatgatagt ttttcttcag
    72601 gtcttttaga atatcctcag tacacacgtc cctatgatta tcgaggcatg gtcgtgccag
    72661 atgtattgat gagtggccac catgaaaaga ttcgtcagtg gcgattgtac gagagtttaa
    72721 agaaaaccta cgagcgcaga ccggatttac ttgaacatta tcaactgaca gtagaagaag
    72781 aaaaaatgct ggcagaaatc aaagaaaaca aagaataaag gagaaaccta tgcaagtaat
    72841 caaacgtaat ggcgaaattg ctgaatttaa tccagataag atttaccaag ccatcttgaa
    72901 ggcagcccaa actgtttatg ttttgacaga tgatttgcgt caaaatcttg ctcaagtcac
    72961 taagaaggta gttttggatt tacaagaagc caaggtggaa cgtgcgacta tcagtatgat
    73021 tcaatctatg gttgaacatc gtttattggg cgcaggttac attaccattg cagaacacta
    73081 tatttcctat cgtttacaac gtgacttgga aagaagtggt tatggagatc atatcgcagt
    73141 tcatttacat tttgaacaaa ttcgctaaga aaaagagtgg gatgaagcaa ctacatctca
    73201 ctctttctta aatctatttt tttgggctgt ttggacagtt gaggggacaa atcgcaggcg
    73261 ttgaatatcg cttatacgga taatccgact cacatttttg gaaaaatttt tcacgataat
    73321 ttgctggcct tgctgatcat atttgatgat gtcacctgta aagcttgtct cagataagat
    73381 aaggtgaaca gcggtttgtt tctggatagc ctcttcaata gtggctgtaa gggagttggt
    73441 ttcagtctgg tcaggttggt catatccatt taaaaaatca tgtattttat ttagaacttg
    73501 ctggaattta tgtctcatat tggcctccct tcttttatat caatattata taaaattttc
    73561 ctaaaatcta caagatttta cgaataaact aatgaaacta aaaaaggaga agaaaatggc
    73621 agaatttaca tttgaaatcg aagagcactt gttaactctt tctgaaaacg aaaaaggttg
    73681 gaccaaggaa attaaccgtg tgagctttaa tggtgcccct gcaaagtttg atattcgtgc
    73741 ttggagtcca gaccatacta aaatgggcaa agggattact ctctcaaatg aagaatttca
    73801 aacgatggtg gatgccttta aaggcaacta atactcttcg aaaatctctt caaaccgcgt
    73861 cagctttgcc ttgccgtatg tatggttact gacttcgtca gtttcatcca caacctcaaa
    73921 acagtatttt gagcagcctg cggctagctt cctagtttgc tctttgattt tcattgagta
    73981 taagttttca aaataaaaga aaaggatatt gagtcatgat aactcgatat ccttttttag
    74041 ttagtaaagt aagcctgatt tttaaggcgt tgaagtaggg gacggctaat aaaactaata
    74101 gccagaagtt tgccaaggtc tggaatgata aagggaagaa cccccacagc aagagctttt
    74161 tcaaatgcca ttccagctag gaaatgcaag ctgagaatcc cgccgacaaa gacaagggca
    74221 tcacccaaga ggtttgcaag aaaaatctta acaacaccac tcttgctgtt ggttagagag
    74281 gaagtaagtc cagagtaaac gagataaaac caaagatagc ctgcagtagg gccaactaaa
    74341 gcctgaaaac cagctccacc tcctgcaaag acaggaagac cgatagcacc tagaagaaga
    74401 tagagtccag cagaaagtac agcctctctc ggtctaaaga cagtagcaat caagccgatt
    74461 gcaaagtttt gcagagtgaa gggaacaggt ccaattggaa gactgatttg tgccaaagca
    74521 gcaatgagag cagccccaat agcagggata gcataaacgt gagctttttt caaaatagtt
    74581 aacctctttt ctaatgtata gtaactatta tactcatata ggagtcgatg tcaaccattt
    74641 tttaaaaaca aggtaacaaa aactgtaaca gccgattttc gtgactagtc aagttggata
    74701 atttttttgt tgattcgaaa atcattaaaa aagaagcaga catatttata tcagcttctt
    74761 ttgtttcgat taacgcatgg ttacaaattc ttcagatgaa gttgggtgaa tcgctacagt
    74821 tgcgtcaaag tcagccttgg ttgctcccat tttgatagca acagcaaatc cttgaatcat
    74881 ttcatcaacg ccgtagccaa ttccgtgaag tccgacaact ttttcttctg aaccagctgt
    74941 tatgagtttg aaacgggatt cttgacggtt gcgagtgcaa gcagagtaca tagatgcaaa
    75001 gcttgatttg taaaccttga tttggtcttg accgtattct ttaatagctt gctcttctgt
    75061 caaaccaaca gttccgatag cagggtgtga aaagacaaca gttggaatag ttgagtaatc
    75121 catttttgca gtagtttttc cgttaaagag acgttcagat agggtacgtc cggccttgat
    75181 tgcaactgga gtcagttctt tctcgcccgt tacatcacct agagcataga ttccctcaac
    75241 aacagtattt tggtattcat ccacttggat aaagccacgt tcgttcagag tcactccagc
    75301 tttttcaagt tgcaagccct taacgtttgg acggcggcct gtagcccaga taacttggct
    75361 agctgtgtga ctagtaccat cttcgaaatg aatggtaatg ccgtcagtag ttttttctaa
    75421 cttgacaggg actttgtgag tgtgaagtgg taagtttgtt ctttccattt ccttgaccaa
    75481 accttcaacg atgtaggaat caaaaccacg taaaggacga tcgcggcgaa caaagagatc
    75541 tgtcttgaca ccaaaagtgt ggagtacgcc agctaattca acggcgatat aaccagcgcc
    75601 tagaatggca actgactctg gaagttcttc ccaggcaaat acatcatcag aagagccacc
    75661 tagctcagca ccaggaatat taggaatact tggatgggca cctgtagcaa tcacgatatg
    75721 tttagcacga atcagttcac catttacgct tacagtatga gaatctacaa attcagcatg
    75781 accttcaatc aagtctacac cgttgcgttt aaaactgcca tcataagaag aacgagcgcg
    75841 atcaatgtag gattcacgat tgcgacgtag ggttgcaaag tcaaagttaa gatcagtagt
    75901 cttaaagccg tagtcttctc caaattgatg gaaagtctca gcgatttgtg ccccgtacca
    75961 catgattttt ttaggaacac aaccgacgtt gacacaggtt ccacctaatt tcttttcctc
    76021 aataacggct gcttgggctc catgttcacc agcacggttc atggtagcga ttcctccgct
    76081 acctccaccg atagcaatga tatcatattc tctcattgaa aactcctttg taatctttta
    76141 aatagtagag cgtctttttt gatagttata ttttattctt tttttgattt gattgcaaaa
    76201 atctgctacg cacaaaaaat tgcaaaaaag cttgccaaat aagtcaagat agtgtattat
    76261 atatctagta caatagaaaa gcaaaattcc gaacgattgt ttaatcctga actgtattgt
    76321 ttgctggagg gaaatttggt ataatagcaa agtattgtaa aaaagaaaag gagtttcatt
    76381 atgaagaaaa agaatggtaa agctaaaaag tggcaactgt atgcagcaat cggtgctgcg
    76441 agtgtagttg tattgggtgc tggggggatt ttactcttta gacaaccttc tcagactgct
    76501 ctaaaagatg agcctactca tcttgttgtt gccaaggaag gaagcgtggc atcctctgtt
    76561 ttattgtcag ggacagtaac agcaaaaaat gaacaatatg tttattttga tgctagtaag
    76621 ggtgatttag atgaaatcct tgtttctgtg ggcgataagg tcagcgaagg gcaggcttta
    76681 gtcaagtaca gtagttcaga agcgcaggcg gcctatgatt cagctagtcg agcagtagct
    76741 agggcagatc gtcatatcaa tgaactcaat caagcacgaa atgaagccgc ttcagctccg
    76801 gctccacagt taccagcgcc agtaggagga gaagatgcaa cggtgcaaag cccaactcca
    76861 gtggctggaa attctgttgc ttctattgac gctcaattgg gtgatgcccg tgatgcgcgt
    76921 gcagatgctg cggcgcaatt aagcaaggct caaagtcaat tggatgcaac aactgttctc
    76981 agtaccctag agggaactgt ggtcgaagtc aatagcaatg tttctaaatc tccaacaggg
    77041 gcgagtcaag ttatggttca tattgtcagc aatgaaaatt tacaagtcaa gggagaattg
    77101 tctgagtaca atctagccaa cctttctgta ggtcaagaag taagctttac ttctaaagtg
    77161 tatcctgata aaaaatggac tgggaaatta agctatattt ctgactatcc taaaaacaat
    77221 ggtgaagcag ctagtccagc agccgggaat aatacaggtt ctaaataccc ttatactatt
    77281 gatgtgacag gcgaggttgg tgatttgaaa caaggttttt ctgtcaacat tgaggttaaa
    77341 agcaaaacta aggctattct tgttcctgtt agcagtctag taatggatga tagtaaaaat
    77401 tatgtctgga ttgtggatga acaacaaaag gctaaaaaag ttgaggtttc attgggaaat
    77461 gctgacgcag aaaatcaaga aatcacttct ggtttgacaa atggtgctaa ggtcatcagt
    77521 aatccaacat cttccttgga agaaggaaaa gaggtgaagg ctgatgaagc aactaattag
    77581 tctaaaaaat atcttcagaa gctaccgtaa tggtgaccaa gaactgcagg ttctcaaaaa
    77641 tatcaatcta gaagtgaatg agggtgaatt tgtagccatc atgggaccat ctgggtctgg
    77701 taagtccact ctgatgaata cgattggcat gttggataca ccaaccagtg gagaatatta
    77761 tcttgaaggt caagaagtgg ctgggcttgg tgaaaaacaa ctggctaagg tccgtaacca
    77821 acaaatcggt tttgtctttc agcagttctt tcttctatcg aagctcaatg ctctgcaaaa
    77881 tgtagaattg cccttgattt acgcaggagt ttcgtcttca aaacgtcgca agttggctga
    77941 ggaatattta gacaaggttg aattgacaga acgtagtcac catttacctt cagaattatc
    78001 tggtggtcaa aagcaacgtg tagccattgc gcgtgccttg gtaaacaatc cttctattat
    78061 cctagcggat gaaccgacag gagccttgga taccaaaaca ggtaaccaaa ttatgcaatt
    78121 attggttgat ttgaataaag aaggaaaaac cattatcatg gtaacgcatg agcctgagat
    78181 tgctgcctat gccaaacgtc agattgtcat tcgggatggg gtcatttcgt ctgacagtgc
    78241 tcagttagga aaggaggaaa actaagatgc agaatctgaa atttgccttc tcatctatca
    78301 tggctcacaa gatgcgttct ttgcttacta tgattgggat tattatcggt gtttcatcag
    78361 ttgttgtgat tatggctttg ggtgattccc tatctcgtca agtcaataaa gatatgacta
    78421 aatctcagaa aaatattagc gtctttttct ctcctaaaaa aagtaaagat gggtctttta
    78481 ctcagaaaca atcagctttt acggtttctg gaaaggaaga ggaagttcct gttgaaccgc
    78541 caaaaccgca agaatcctgg gtccaagagg cagctaaact gaagggagtg gatagttact
    78601 atgtaaccaa ttcaacgaat gccatcttga cctatcaaga taaaaaggtt gagaatgcta
    78661 atttgacagg tggaaacaga acttacatgg acgctgttaa gaatgaaatt attgcaggtc
    78721 gtagtctgag agagcaagat ttcaaagagt ttgcaagtgt cattttgcta gatgaggaat
    78781 tgtccattag tttatttgaa tctcctcaag aggctattaa caaggttgta gaagtcaatg
    78841 gatttagtta ccgggtcatt ggggtttata ctagtccgga ggctaaaagg tcaaaaatat
    78901 atgagtttgg tggcttgcct attactacca atatctctct tgctgcgaat tttaatatag
    78961 atgaaatagc tagtattgtc tttcgagtga atgataccag tttaacccca actctgggtc
    79021 cagaactggc acgaaaaatg acagagcttg caggcttaca acagggagaa taccaggtgg
    79081 cagatgagtc cgttgtattt gcagaaattc aacaatcgtt tagttttatg acgacgatta
    79141 ttagttccat cgcagggatt tctctctttg ttggaggaac tggtgtcatg aacatcatgc
    79201 tggtttcggt gacagagcgc actcgtgaga ttggtcttcg taaggctttg ggcgcaacac
    79261 gtgccaatat tttaattcag tttttgattg aatccatgat tttgaccttg ttaggtggct
    79321 taattggctt gacaattgca agtggtttaa ctgccttagc aggtttgtta ctgcaaggtt
    79381 taatagaagg tatagaagtt ggagtatcaa tcccagttgc cctatttagt cttgcagttt
    79441 cggctagtgt tggtatgatt tttggagtct tgccagccaa caaggcatcg aaacttgatc
    79501 caattgaagc ccttcgttat gaatgagatc aacaagatgg acactcgtct atcttgtttt
    79561 tgtatggatt tccctatcga aattcattaa aaatgtgata taatgaagtg ttagaaaaac
    79621 aggtttcatt tgcctggaaa ggaaaaatta tgtctgaaaa aaatttttat attacaacgc
    79681 cgatttacta tccatctggg aaacttcata tcggttctgc ctacacaact atcgcatgtg
    79741 atgtcctagc acgttacaaa cgcctgatgg gctacgatgt attttatctg acaggtcttg
    79801 atgaacatgg tcagaaaatc cagcagaaag cggaagaagc tggtattaca cctcaagcct
    79861 atgttgatgg aatggcggtt ggagttaaag aactctggca attactagat atctcatacg
    79921 ataaatttat ccgtacaact gatgactacc atgaaaaagt tgtcgcacag gtctttgaac
    79981 gcttacttgc tcaagatgat atctacttgg gtgaatactc tggttggtat tcagtatcag
    80041 acgaagaatt ctttacagaa agccagctgg cagaagtttt ccgtgatgaa gctggaaatg
    80101 tgactggtgg tattgctcca tcaggtcatg aggttgaatg ggtttctgaa gaatcatact
    80161 tccttcgcct tagcaaatac caagaccgtt tggtcgaatt tttcaaagct catcctgaat
    80221 ttatcacgcc agatggtcgc cttaatgaaa tgctacgcaa cttcatcgag ccaggcttgg
    80281 aagatttggc ggtatctcgt acaaccttta catggggagt gcctgtccca tcaaatccaa
    80341 aacacgttgt ctacgtttgg attgatgccc ttcttaacta tgcgacagct cttggctacg
    80401 ctcaagacga acatggtaac tttgacaagt tctggaatgg aacagtcttc catatggtag
    80461 gaaaagatat ccttcgcttc cactctatct actggccaat ccttcttatg atgttggatg
    80521 ttaaattacc tgatcgtttg attgcccatg gttggtttgt catgaaagac ggaaaaatgt
    80581 ctaagtcaaa agggaatgtc gtttaccctg aaatgttggt agagcgttat ggactagatc
    80641 cacttcgtta ctacctcatg cgtaaccttc cagttggttc agacggaacc tttactcctg
    80701 aagactatgt cggccgtatc aactatgaat tggctaatga ccttgggaac ctccttaacc
    80761 gtacggtttc catgattaat aagtactttg atggacaaat ccctgcctat gtagaaggtg
    80821 tgactgaatt tgaccatgtt cttgctgagg ttgcagaaca atcaatcgca gacttccata
    80881 cacacatgga agcagttgac tatccacgtg cgcttgaagc agtctggact ctgatctctc
    80941 gtaccaataa atacatcgat gagaccgcac catgggtctt ggccaaggat gaagctcttc
    81001 gtgaccaatt ggcaagtgtc atgagccact tggcagccag cattcgtgta gttgctcact
    81061 tgattgaacc atttatgatg gaaactagtc gtgcagtttt gactcaactt ggtttggaag
    81121 aagtttctag tcttgaaaac ttgagtttgg ctgacttccc agcagatgtg actgtagttg
    81181 ccaaaggaac acctatcttt ccacgtctaa atatggaaga agaaatcgcc tatatcaagg
    81241 aacaaatgga aggcaataaa ccagcagtcg aaaaagaatg gaatccggac gaagttgagc
    81301 tcaaactaaa caaggatgaa atcaagtttg aagactttga caaggttgaa atccgtgtcg
    81361 cagaagtcaa agaagtgtct aaagtagaag gttcagataa gttgcttcaa ttccgcttgg
    81421 atgctggtga tggagaagat cgtcagattc tttcaggaat tgcaaaatac tatccaaatg
    81481 aacaagaatt ggtcggcaag aaagttcaaa tcgttgctaa cctcaaacca cgtaaaatga
    81541 tgaaaaaata tgtcagccag ggtatgattc tctcagctga acatgatggc aaattaaccc
    81601 ttctcacagt tgatccagct gtaccaaatg gaagtgtgat tgggtaaaag tagacaggac
    81661 tagttcagac tagttctgtt tttttattta tactcaatga aaatcaaaga gcaaactagg
    81721 aagctagccg caggttgctc aaaacatggt tttgaggttg tagatgaaac tgacgaagtc
    81781 agctcaaaac actgttttga ggttgtagat gaaactgacg aagtcagtaa ccatacatac
    81841 ggtagggcga cgctgacgtg gtttgaagag attttcgaag agtattaact attatgcttt
    81901 acaaactagt gtagaagtga tatactatag gtgaagttac tagtaggtat tacaaaatag
    81961 attagaaggg agaagtgatg aaagaaactc agctattaaa aggtgttctt gaaggttgtg
    82021 tcttggatat gattggtcaa aaagagcggt atggttatga gttggttcag actttgcgag
    82081 aggctggatt tgatactatc gttccaggaa ctatttatcc tttgttgcaa aagttagaaa
    82141 aaaatcaatg gataagaggc gacatgcgcc cgtcgccaga tggtccagat cggaagtatt
    82201 tttcattaat gaaagaagga gaagagcgtg tctcagtctt ttggcaacaa tgggacgatt
    82261 tgagtcaaaa agtagaaggg attaagaatg ggggttaaac catgaagaaa atgaagtatt
    82321 acgaagaaac aagcgctttg ctacatgagt tttctgagga gaatcaaaag tattttgagg
    82381 agttgtggga aagttttaat cttgctggat ttctctatga tgaagactat ctcagagagc
    82441 agatctattt gatgatgcta gatttctcag aagcagaacg agatggcatg agtgcagagg
    82501 attatctagg taagaatcct aaaaaaataa tgaaagagat tctcaaggga gcacctcgca
    82561 gttctatcaa agagtccctt ttgacgccaa ttcttgtcct ggcggtatta cgttattatc
    82621 aactactaag tgatttttct aaaggtcctc tcttaacagt caatttgctc acatttttag
    82681 ggcaacttct tatttttctg attggatttg gacttgtggc cacaatttta cgaagaagtt
    82741 tagtccaaga ttctcctaaa atgaaaattg gcacttacat tgttgttggg actatagttc
    82801 ttctagttat tttaggatat gtaggaatgg caagcttcat acaagaagga gccttttata
    82861 ttccggctcc ctgggatagt ttgtctgtct ttacgatttc gctagttatc ggtatttgga
    82921 attggaaaga aacggtcttt cgtccatttg tcagtatgat tattgcccat cttgtggtgg
    82981 gttctctgct ccgttattat gagtggatgg gaatttcaaa tgttttcctt acaaaagtta
    83041 ttcctttagc tgtcctcttt attggaatct ttgtcttgtt ccgtgggttt aagaagataa
    83101 aatggagtga agtatagtca aaaagccgtt gcaaagcggt tttttgttat aatgaaggga
    83161 agaatgttag aaattaaagg agaaaaattt gatgagatac ataactcttg gtcaagatga
    83221 caaagaatta tcagaaattg ttctcggaat gatgagaata aaagataagt ctgtaaaaga
    83281 agttgaagag cttgtagaaa cagcactttc tgttggaatc aatgccttcg acttggctga
    83341 tatttatggt cgtggtcgtt gtgaagaact gttaggtctt gtcctaaaaa atcgtccaga
    83401 tttaagagaa aagatgtgga ttcagtccaa atgtggcatt cgcattgaag aatttaccta
    83461 ttttgatttt tctaaggact atattataaa atcagtagac ggtattttgc aaagattgaa
    83521 gattgatcat ctagatagct tgctccttca tcgaccagat gctttgatgg aatctgacca
    83581 agtagcagaa gcctttaatc tcctttataa acaaggtaaa gttcgagatt ttggagtttc
    83641 taatcaaaat cctatgatga tggagttgct taaaaaagat gtcaagcagc cgttagctgt
    83701 taatcagcta caattgagtg cggcttttac tccaggattt gaatcagctt ttcatgttaa
    83761 tatggaagat agtcaagcag ctatgcgaga tggcagcatt tttgaatatt gccaattaca
    83821 cgatgtggtc attcaagcat ggtctgtctt acaattcggg tattttaaag ggaattttgt
    83881 tggaaatgag aaatttcaag ctttaaatca agtacttgat cgtttagcta ttaaatatgg
    83941 agtaacctct tcaactattg ccatttcttg gatattgcgt tatccagcaa aaatgcaggc
    84001 agtcgtaggt acaacaaatc ctaagcactt gagagaagtt agccgagcgg caaactttag
    84061 cttaacaaga aaagaatggt atgaaattta tcttgctgca gggaataatt tgccgtaagt
    84121 agtagcaggt ttgaataact cacattcaaa aagccgtata aagcggtttt ttgctataat
    84181 taaatgaaga atgtagaatt aaaggagaaa aacatgacat ttgaagagat cctgcctggg
    84241 ttaaaggcta agagaaaata tgtacgaact ggttggggag gtgcggaaaa ctatgtccaa
    84301 ctctttgata ccatcgagca aaatgggctt gcacttgaaa tgacacctta tttcctaatc
    84361 aacgtttctg gcgaaggaga aggtttttcc atgtggagcc cgacagtttg tgatgttttg
    84421 gcaacggatt gggtagaagt gcatgactaa acgtgtactc attacaggag tgagttcagg
    84481 gatcggattg gctcaagctc gcctcttttt agagaagggc tatcaagttt atggagttga
    84541 ccaaggtgaa aagccactct tagagggtga ttttcacttt ttacagagag atttgacctt
    84601 ggacttggaa cctatttttg actggtgccc tcaggtggat gttttgtgta atactgctgg
    84661 agttttggat gattacaaac cactgttgga acaaacggcg caggacattc aagagatttt
    84721 tgaaatcaac tacattattc cagtagagtt gactcggtat tatttgacac aaatgctgga
    84781 aaataaaaag ggaatcatca tcaatatgtg ttccattgct tctagcctag caggtggagg
    84841 tggtcacgcc tatacttcat ccaagcatgc cttggctggc ttcaccaagc agttggctct
    84901 agactatgct gaagctggga ttcaggtctt tggtatcgct ccaggagcag tcaagacagc
    84961 tatgaccgct gcggattttg aaccaagtgg cttagctgac tgggtggcta gtgaaacacc
    85021 aatcaagcgc tggattgaac cagaggaaat agcagagctt agtctttttt tagcaagtgg
    85081 aaaagcgagc gccatgcaag gacaaatctt gacaatagat ggtggctggt ctttgaagta
    85141 ggaggagttg gatggaaatc aaaaatcact ttggggtcta ctgtgtttgc tttgaaaatg
    85201 gaaagttact ttgcattgaa aaaacgagag gcccttatca acatcggtat gatctacctg
    85261 gaggcagtca gcaacttggt gaaggactga cggaaacgct gactagagaa gttatggaag
    85321 agacgggatt tactgttaga agctactcta atcctcgaat ctacgatgtt ttcgtcagag
    85381 aagagttaaa aaattttatg gttcaccatg tcatggcctt gtatgatgtt gaaatgaatg
    85441 agagtgcacc tcaagttacg atttcggaag ctgtgtctga tggtgcgaat gattcacttg
    85501 gatatatttg gatggatatt caagagatta cagaagaaaa tgcatcgcca ttagtcttga
    85561 aggttaagtc tgaattatta ggatttccag aactggacaa gacttcttac atgaattgga
    85621 aggtgaatga tgagaaatca acttgccctt agtggcgaaa aaattcttga aaaaatttat
    85681 cctcaactat ttcaccacgt cggcatgatt cgtggggaat atttgttgag agagcttaat
    85741 caaaacatca tattagcaag ttgtcagcaa tttgtaaaag attatctaga gactatctgc
    85801 tccctgtact cagatgaaga agtttggtat cgttttactg aattaacgaa tacagaagcc
    85861 aattgtttag tggggactaa agagtttttt gacgaagggc atcccttgtt tggctataga
    85921 ggaactaggc gtttactggc gtgtttggat gaatttcagg ctgaagcaca tgtcgttaca
    85981 gaagtttatc aaaccacccc caatctatct gttatctttc cttttgtcaa tgatgccgac
    86041 caattaaaac aagctattac agtattgcgt cagtatggct ttactgggaa agtcggaacg
    86101 atgattgaat taccgtcagc gtattttgac ttatctagta tactggaaac gggcatttca
    86161 aagattgtag ttggaatgaa tgatttgact tcctttgttt ttgcgactat gagaaacagt
    86221 caatggcatg atatggaaag tccaataatg ttagatatgc taagagatat gcaggataaa
    86281 gcaagaaaga acaagattaa ttttgctgta gcaggctatc tgaatacttc tttcatacaa
    86341 aaaatgaatc agttgggtat caagtgcatt atccactaca gttctattcc agagattttt
    86401 gatttagaga ttgaccatcc agatcatctt aaacacataa aagaagaaag taaaaaatta
    86461 caaaggagta cccatgatac cgcaagaaat gtggaataaa tacaaacaaa tcaatccttc
    86521 tatcggagat gaaatcgatg cctgggcttt tggagttgaa ccagaccttt tagcggattt
    86581 ggtgtttaaa ggagaaaaga cagcaacagc atcagcctat gacctctatg tactagaaga
    86641 cgaaccactt ccccaagtag ggaccttcga tgtcatttta gatagtcaaa atcaggctgt
    86701 ctgcattgtc gaaattacaa aggtttctgt taaacccttc aatcgagtgt cagctgacca
    86761 tgcctataag gaaggtgagg gaaacaagac acttgtctat tggcgccagg ttcatgagga
    86821 ttttttcaga gactgcttgg gtgaagcagg attgactttt acacctgaaa gcaaggttgt
    86881 tttagaagaa tttcgcaagg tctacccact gtagactatt agaaggaaga aagttttgga
    86941 aatcgctgtc caatcctttt ttctcaagca aaatatgata taataagttt gtttgaagaa
    87001 gagcagcagc tcttaaactt agaataggag aaaactatgc aagcagttga acattttatt
    87061 aagcaatttg ttcctgaaca ttatgattta tttttagatt tgagtcgtga gaccaagact
    87121 ttttctggga aagtgaccat cactggtcaa gcacagagtg accgcatctc cctccaccaa
    87181 aaagacttgg aaatcacctc tgtagaagtt gcaggtcaag ctcgtccatt tacagttgac
    87241 catgacaatg aagcccttca tatcgaattg gctgaggctg gtcaagttga attggttctt
    87301 gccttttctg gtaaaattac agacaacatg acagggattt acccttctta ttatacagtt
    87361 gatggagtca agaaggaggt cttgtctact cagttcgaga gccattttgc gcgcgaagct
    87421 ttcccatgtg tggatgagcc tgaagccaaa gcaacttttg acctctctct tcgctttgac
    87481 caagcagaag gtgaattggc cttgtcaaac atgccagaaa tcgatgttga aaaccgtaag
    87541 gaaacaggta tctggaagtt tgagacaaca cctcgcatgt cttcttactt gttggccttt
    87601 gttgctggtg atttgcaagg ggtgaccgct aaaactaaaa atggtaccct ggtaggtgtc
    87661 tactcaacca aagcacatcc actttcaaat cttgatttct cactggatat cgctgttcgc
    87721 tctatcgagt tttacgaaga ttactatgga gttaagtatc caattcctca atctctccac
    87781 atcgcccttc ctgacttctc agctggtgct atggaaaact ggggtcttgt gacctaccgt
    87841 gaagtttact tggttgtcga tgagaactct acatttgcta gccgtcaaca agttgccctt
    87901 gttgtggccc atgaattggc tcaccaatgg tttgggaacc tcgtgactat gaaatggtgg
    87961 gatgaccttt ggctcaatga aagtttcgct aatatgatgg aatacgtctg tgtggatacc
    88021 atcgaaccaa gctggaatat ctttgaagat ttccaaacag gtggagtacc tcttgctctt
    88081 gaacgtgacg ctactgatgg cgttcagtct gtccacgtcg aagttaaaca tccagatgaa
    88141 atcaatacac tctttgacgg cgctatcgtc tatgccaaag gaagccgtct catgcatatg
    88201 cttcgccgtt ggctaggaga tgctgatttt gctaaaggtt tgcacgccta ctttgaaaaa
    88261 caccaataca gcaacaccat tggtagtgac ctttgggatg cccttggtca agcgtcagga
    88321 cgtgatgtcg cagccttcat ggattcttgg ttggaacagc ctggttaccc agttcttact
    88381 gttaaagttg aaaatgatgt cttgaagatt tcacaaaaac aattcttcat cggtgagaac
    88441 gaagacaaga accgtctctg ggtggtgccc ctcaatagca actggaaagg cttgcctgat
    88501 acactcgaaa ctgaaagtat cgaaatccct ggctacgcag ctcttcttgc tgaaaatgaa
    88561 ggagctcttc gtctcaacac tgaaaatact gcccactata ttaccgacta tcaaggagac
    88621 ttgttagaag ctgttcttgc tgagctagag acacttgata acacaagcaa actgcaaatt
    88681 gttcaagaac gtcgtttgtt ggctgaggca gggcacattt cttatgcaga cttgcttcca
    88741 gttcttgata aacttgctaa ggaagagtct tatctggtgg tttcagctgt ttctcaagtg
    88801 atttcagcct ttgagcgctt tattgatgaa ggaacggatg ctgaaacagc cttcaaagga
    88861 ctggttgcta aattggctcg tcataactat gaccgtcttg gttttgaagc taaagacgga
    88921 gaatcagatg aggatgaatt ggttcgtcag ctggctgttt cgatgatgat tcgctcaaat
    88981 gatgcagaag ctagtcaagt cgctagccaa atcttcgcaa cacacaagga gaatcttgca
    89041 ggactcccag cagctattcg ctcacaagtt ctgattaatg agatgaaaca tcatgagact
    89101 aaagacttgt tagcacttta tcttgatact tatactcacg caacagatgc tgtctttaaa
    89161 cgccagttgg cagcagctct tgcatacagt acagatgcgg ataatatcca aaacttgatt
    89221 acttcttgga aggacaaatt tgtggtcaaa ccacaggact tgtctgcttg gtattaccaa
    89281 ttcctagctc atcaagcaac tcagaaaaca gcttggtctt gggcgcgtga aaactgggct
    89341 tggattaagg cagcccttgg aggagatatg agctttgata gctttgttat ccttcctgct
    89401 catgtattta agactcagca acgcttggcg gaatacaagg agttctttga accgcaactt
    89461 tctgaccttg ctcttagccg taacatcggt atgggaatca aggaaattgc agcgcgtgtt
    89521 gacttgatta gccgtgaaaa agctgcagtc gaagcagttg ttcttcaata cggaaatgca
    89581 taaataagcc taaaataaaa agaaaactca gctatctcat gtaaaatgca gagagttgag
    89641 tttttttaag gcaaatttgg tataatagtt ttaataagga ggagtttctc atgataaaaa
    89701 tcttattggt tgaggatgac ctaggtctgt caaattcagt atttgacttt ttagacgatt
    89761 ttgcggatgt tatgcaggta tttgatggag aagaaggtct ctacgaagct gagagtggtg
    89821 tctatgactt gattttgctg gatttgatgt tgccagaaaa aaatggtttc caagtcttaa
    89881 aagaattgcg tgaaaaggga attacgacac cagttctgat tatgactgcc aaggaaagtt
    89941 tggatgacaa gggacatgga tttgaactgg gagcggatga ttatctgacc aaacctttct
    90001 acctagaaga acttaaaatg cggattcagg cccttctcaa acgttcaggg aagtttaatg
    90061 aaaacacctt gacttatggg aatatcgtgg ttaatttatc aaccaatacc gttaaagttg
    90121 aagatactcc tgtcgaattg ctggggaaag agttcgattt actagtttat ttccttcaaa
    90181 atcaaaatgt gattttgcct aagacgcaga tttttgaccg tctatgggga tttgatagtg
    90241 atacaacgat ttcggttgtc gaagtctatg tttcaaaagt ccgtaagaaa ttaaagggaa
    90301 ccacttttgc agagaatttg caaaccttgc gtagtgttgg gtatctttta aaagatgttc
    90361 agtaaactta aaaaaacatg gtatgcggat gactttagtt attttatccg caacttcggt
    90421 gtcttcaccc tgattttttc tacaatgact ctgattattt tacaagtcat gcattcgagt
    90481 ctttatactt cggtggacga taagcttcat ggactgagtg aaaatcctca agcagttatt
    90541 cagctggcta taaatagggc aacagaagag attaaagatt tagaaaatgc tagggcggac
    90601 gctagtaaag tagaaataaa acctaatgtc agttccaata cggaagtcat tctctttgat
    90661 aaagacttta ctcaacttct ttctggaaat cgatttttgg gcttggataa gattaagtta
    90721 gaaaagaaag aactaggaca tatctaccag attcaggttt ttaatagcta tgggcaggaa
    90781 gaaatctatc gtgtgatttt gatggagacc aatattagtt cggtttcaac caatataaag
    90841 tatgctgctg tcttgattaa taccagtcag ttggagcagg ctagtcaaaa gcatgagcaa
    90901 ttgattgtgg tcgtgatggc tagtttctgg attttgtctt tacttgccag tctctatcta
    90961 gctagggtca gtgttaggcc cctgcttgag agtatgcaga agcaacagtc ttttgtggaa
    91021 aatgccagtc atgagttacg aactccactc gcagttttgc aaaatcgctt agagaccctt
    91081 tttcgtaagc cagaagctac cattatggat gtgagcgaaa gcattgcatc gagtttggaa
    91141 gaagtccgaa atatgcgttt tttaacgaca agcttgctga acttagctcg gagagatgat
    91201 gggattaagc cggagcttgc agaagttcca actagctttt ttaatacaac tttcacaaac
    91261 tacgagatga ttgcttcgga aaataatcgt gtcttccgtt ttgaaaatcg tatccatcga
    91321 acaattgtca cagatcagct tcttctgaaa caactgatga ccattctttt cgataatgcc
    91381 gtcaagtata ctgaggagga tggtgaaatt gattttctta tctcggcgac cgatcgcaat
    91441 ctttatttac ttgtttctga taatggaatc ggtatttcga cagaagataa aaagaaaatt
    91501 tttgaccgtt tttatcgagt agacaaggct agaacccggc aaaaaggtgg ttttggatta
    91561 ggattatccc tagccaagca aattgtagat gctctaaaag gaactgttac tgtcaaagat
    91621 aataaaccca agggaacaat ctttgaagtg aagattgcca ttcagacacc atctaaaaag
    91681 aaaaaataaa aatatcgctc caattggggc gatattttgg atttatcttc tacgttttcg
    91741 tttgataata gaccgttgaa cttttaaaac aagtaagctg aatccgattg ctgcggcaaa
    91801 ggcaagagca gttgataatt ttaatgctaa aaagataaaa ctaaagatag caatacagat
    91861 acaaaaaaca gcgatattaa taaaaaatag gatttccttg agattggcat cagattgcgc
    91921 ttcaggtgta taagcttggt aatgaggaag ctgctggttt aattcttctt gatagtctac
    91981 ctcataggat tgtaattttc ttacgggcat gattctctcc ttaacagtac atacctattt
    92041 tatcattttt tcggcagaga attattacag aaaggttaca aaaagaataa agtccctttt
    92101 cattttcaaa acatggctga ttttggagaa atgtggtata atttttctta tggaaaagat
    92161 tgtcattaca gcaactgctg aaagtattga acaagttgaa caactactcg aagctggcgt
    92221 agaccgtatc tatgtcggtg agaaagattt tggccttcgt ctgccaacga cctttagtta
    92281 tgaccaatta cgtgaaatcg ctaagttggt tcatgatgct ggtaaggaat tgctcgttgc
    92341 ggtcaatgct ctcatgcacc aagatatgat ggaccgtatc aagcctttct tagacttctt
    92401 ggaagaaatc aagacagact atattacgat tggggatgca ggcgtctttt acgtagttaa
    92461 ccgcgatggt tattcattta agaccatcta cgatgcttca accatggtaa ctagcagtcg
    92521 tcagattaac ttctggggac aaaaggctgg cgcatctgag gctgttttgg cgcgtgaaat
    92581 tccatcagct gaacttttca aaatgccaga gattttggaa attcctgctg aagttttggt
    92641 ttacggtgct agcgtcatcc atcattctaa acgtccactc ttgcaaaact actataactt
    92701 tacacatatc gatgatgaaa agacgcataa acgtgacctc ttcttggctg agccaagtga
    92761 tccagagagc cactattcca tttttgaaga taatcatggg acccatatct ttgccaacaa
    92821 tgaccttgat ttgatgatca aattaacaga attggtggag catggcttta ctcgctggaa
    92881 actagaaggg ctctacactc ctggtcagaa ctttgttgag attgcaaaac tctttatcca
    92941 agcgcgtaac ttgattcaag agggcaactt tagccatgat caagtcttct tgctggatga
    93001 agaagttcgt aaacttcacc ctaaaaaccg tttccttgat acaggatttt atgactacga
    93061 tcctgacatg gttagataaa atacatgatt cgttgagaga aggaagatgc aaacattttt
    93121 tctctcaatt tttcgtattt cttcactatt ttacaaaaat cagcaggcta gaatgctcta
    93181 ttcgatggga tttttaagaa aagtagtgtt cttgagtttg aaaattatcc tatgtttgca
    93241 ggtgccaaat ggcccttttt ttggtataat tttttataat gaaaacgatt ggtaatcgct
    93301 atgttgtggt ggatttagag gcaactagca caggtagtaa ggctaaaatt atccaagtgg
    93361 gaattgtcgt gattgaggac ggagaaatcg tcgatcacta tacgacggat gtcaatccac
    93421 atgaaccctt ggatgctcat atcaaagaac tgacaggatt gacagaccaa cgtctggcgc
    93481 aagcacctga tttttcgcaa gttgccagaa aaatatttga cttggtggag gatgggattt
    93541 ttgtagccca taatgttcag tttgatgcta atctcttggc ggaaaattta ttttttgaag
    93601 gctatgagct aagaaaccct cgtgttgata cggtcgaatt ggcccaggtc tttttccctg
    93661 aactggaaaa atatagcttg ccgattttgt gtcgagaatt aggaattcct cttaaacacg
    93721 cacacacagc cctttcagat gcccaagcta cagcagaatt acttcttttt ttacgggaaa
    93781 agatgaccca gcttcctaaa ggtctcttgg aacgcttgct ggaaatggct gacgctctcc
    93841 tatatgagtc ctacctggtt attgaggaaa cttatcgcaa ccaatctatc ctgagttctc
    93901 cagacttggt ccaagttcaa ggtctgtatt ttaagaaaac ggcagcttct ctggagctac
    93961 gaaaactatc tcaagacttt tctaaaaata tttctctgtt gaaccttgaa gtgagggagg
    94021 aacaagaaag ttttgctaaa gaggttggct tgctattgaa agatgaacct gtctttctga
    94081 ttcaagcgcc gacagggatt gggaaaacct atggctatct cttacccgct ttatctcaat
    94141 ccaaagagcg acaaattgtt cttagtgttc cgacaaagat tcttcaaaat caaatcatgg
    94201 aagaagaagg taaacgtctc aaggaagtgt tccatacaga tattcatagc ttaaagggac
    94261 cacaaaatta tctgaagttg gatgcctttt atcattcctt gcaggaaaat gatgaaaatc
    94321 gcttatttag acgctttaaa atgcaagtct tggtctggct tactgagaca gagacaggag
    94381 atttggatga aatcgggcaa ctctaccgtt accaacattt tctagcagac cttcgtcatg
    94441 atgggaattt atcatcccag agcttatttg tgacggaaga tttttggaaa cgtagtcaag
    94501 aaagggcaga gacttgcaag cttttagtga ctaatcatgc ctatctcgtg accagacttg
    94561 aagataatcc tgaatttgtc agtgaccgtt tactgattat tgatgaagtc caaaagattt
    94621 tgttagctct agaaaatctg cttcaagaga cctacgatat acaatctatt atcgatttaa
    94681 ttgataaggc tttagtagga gaagaaaaca gggttcaaca acggatacta gaaagtattc
    94741 gctttgagtg tctctacttg atagaacaat ttcagtctgg taaatctagg aaaaatatct
    94801 tagattctct ggacaatctc catcagtatt tttcagaatt agaagtagaa ggctttgatg
    94861 agctggttcg ctattttaca gctgaaggtg attactggct tgaagtaact gaaacgagtc
    94921 aaaagaaaat tcagatttct tctacaaaat caggccgtac tcttctgtcc tctttacttc
    94981 ctgagagttg ccaagtcctg ggagtatcgg ctactcttga gattagtcag agggtttctt
    95041 tggcagacct tttaggctat cctgaagcta aatttgtcaa gattgaatct cggggaaaac
    95101 aggaacaaga agtggtcatg gtcaaagatt tccctctggt aacagaaacc tccttagaag
    95161 tctatgccag agaggtagct gctttactag tggaaattca agctttccag caaccgattt
    95221 tggttctctt taccgctaaa gacatgcttc tagcagtatc ggatttactt acagttagcc
    95281 acttggccca gtataaaaat ggggatgttc atcagctaaa gaaacgcttt gaaaaaggtg
    95341 aacaacaaat cttgcttggt gcagcaagtt tctgggaggg agttgatttt tcaagccatc
    95401 cttttgtgat tcaagttgta ccgaggcttc ctttccaaaa tcctcaagaa cccttgacga
    95461 aaaagattaa tcaagaactg aatcaagaag ggaaaaatgc cttttatgat tatcaattgc
    95521 caatggccat tattcgttta aaacaggctt tgggaagaag tatgagacgt gaataccaac
    95581 gttccttaac tcttattttg gataggagaa tcgtcggaaa acgatacggc aaacaaatag
    95641 tagcatctct agcagaagaa gcgactgtta aaaccatctc tcgatccgaa gttgacgagg
    95701 ctattgatag attttttaat gaactttgat aaatagtatt gtatgaaagt ataaggttag
    95761 tatatatgaa acgttctctc gactcaagag tcgattacag tttgctcttg ccagtatttt
    95821 ttctactggt catcggtgtg gtggctatct atatagccgt tagtcatgat tatcccaata
    95881 atattctgcc cattttaggg cagcaggtcg cctggattgc cttggggctt gtgattggtt
    95941 ttgtggtcat gctctttaat acagaatttc tttggaaggt gacccccttt ctatatattt
    96001 taggcttggg acttatgatc ttgccgattg tattttataa tccaagctta gttgcatcaa
    96061 cgggtgccaa aaactgggta tcaataaatg gaattaccct atttcaaccg tcagaattta
    96121 tgaagatatc ctatatcctc atgttggctc gtgtcattgt ccaatttaca aagaaacata
    96181 aggaatggag acgcacggtt ccgctggact ttttgttaat tttctggatg attctcttta
    96241 ccattccagt cctagttctt ttagcacttc aaagtgactt ggggacggct ttggtttttg
    96301 tagccatttt ctcaggaatc gttttattat caggggtttc ttggaaaatt attatcccag
    96361 tatttgtgac tgctgtaaca ggagttgctg gtttcttagc tatctttatt agcaaggacg
    96421 gacgagcttt tcttcaccag attggaatgc cgacctacca aattaatcgg attttggctt
    96481 ggctcaatcc ctttgagttt gcccaaacaa cgacttacca gcaggctcaa gggcagattg
    96541 ccattgggag tggtggctta tttggtcagg gatttaatgc ttcgaatctg cttatcccag
    96601 ttcgagagtc agatatgatt tttacggtta ttgcagaaga ttttggcttt attggctctg
    96661 tcctggttat tgccctctat ctcatgttga tttaccgtat gttgaagatt actcttaaat
    96721 caaataacca gttctacact tatatttcca caggtttgat tatgatgttg ctcttccaca
    96781 tctttgagaa tatcggtgct gtgactggac tacttccttt gacggggatt cccttgcctt
    96841 tcatttcgca agggggatca gctattatca gtaatctgat tggtgttggt ttgcttttat
    96901 cgatgagtta ccagactaat ctagctgaag aaaagagcgg aaaagtccca ttcaaacgga
    96961 aaaaggttgt attaaaacaa attaaataag gagaaaatca tggtaaaagt agcagttatg
    97021 ttagctcagg gctttgaaga aattgaagcc ttgacagttg tagatgtctt gcgtcgagcc
    97081 aatatcacat gtgatatggt tggttttgaa gagcaagtaa cgggttcgca tgcaatccaa
    97141 gtaagagcag atcatgtctt tgatggagat ttatcagact atgatatgat tgttcttcct
    97201 ggaggtatgc ctggttctgc acatttacgt gataatcaga ccttgattca agaattgcaa
    97261 agcttcgagc aagaagggaa gaaactagca gccatttgtg cggcaccaat tgccctcaat
    97321 caagcagaga tattgaaaaa taagcgatac acttgttatg acggcgttca agagcaaatc
    97381 cttgatggtc actacgtcaa ggaaacagta gtggtagatg gtcagttgac aaccagtcgg
    97441 ggtccttcaa cagcccttgc ctttgcctac gagttggtgg agcaactagg aggggacgca
    97501 gagagtttac gaacaggaat gctctatcga gatgtctttg gtaaaaatca gtaaaacggg
    97561 agttattctc tcgtttttta tgtggaaaac tcagggaaat catcgctttt ttcataaaaa
    97621 aatgctataa tgaagggtat gaaatatcac gattacatct gggatttagg tggaacttta
    97681 ctggataatt atgaaacttc aacagctgca tttgttgaaa cattggcact gtatggtatc
    97741 acacaagacc atgacagtgt ctatcaagct ttaaaggttt ctactccttt tgcgattgag
    97801 acattcgctc ccaatttaga gaatttttta gaaaagtaca aggaaaatga agccagagag
    97861 cttgaacacc cgattttatt tgaaggagtt tctgacctat tggaagacat tttaaatcaa
    97921 ggtggccgtc attttttggt ctctcatcga aatgatcagg ttttggaaat tttagaaaaa
    97981 acctctatag cagcttattt tacagaagtg gtgacttcta gttcaggctt taagagaaag
    98041 ccaaatcccg aatccatgct ttatttaaga gaaaagtatc agattagctc tggtcttgtc
    98101 attggtgatc ggccgattga tatcgaagca ggtcaagctg caggacttga tacccacttg
    98161 tttaccagta tcgtgaattt aagacaagta ttagacatat aagaaaaagg aataagatga
    98221 cagaagaaat caaaaatctg caggcacagg attatgatgc cagtcaaatt caagttttag
    98281 agggcttaga ggctgttcgt atgcgtccag ggatgtacat tggatcaacc tcaaaagaag
    98341 gtcttcacca tctagtctgg gaaattgttg ataactcaat tgacgaggcc ttggcaggat
    98401 ttgccagcca tattcaagtt tttattgagc cagatgattc gattactgtt gtggatgatg
    98461 ggcgtggtat cccagtcgat attcaggaaa aaacaggccg tcctgctgtt gagaccgtct
    98521 ttacagtcct tcatgctgga ggaaagttcg gcggtggtgg atacaaggtt tcaggtggtc
    98581 ttcacggggt ggggtcgtca gtagttaatg ccctttccac tcaattagac gttcatgtcc
    98641 ataaaaacgg taagattcat taccaagaat atcgtcgtgg tcatgttgtt gcagaccttg
    98701 aggtggttgg gtatacagat agaactggaa caacggttca cttcacaccg gacccagaaa
    98761 ttttcactga aacaacaatc tttgattttg ataaattaaa taaacggatt caagagttgg
    98821 cctttctaaa tcgcggtctt caaatttcaa ttacagataa gcgccaaggt ttggaacaaa
    98881 ccaagcatta tcattatgaa ggtgggattg ctagttacgt tgaatatatc aacgagaaca
    98941 aggatgtaat ctttgataca ccaatctata cagacggtga gatggatgat atcacagttg
    99001 aggtagccat gcagtacaca acaggttacc atgaaaatgt catgagtttc gccaataata
    99061 ttcataccca tgaaggtgga acgcatgaac aaggtttccg tacggcactg actcgtgtta
    99121 tcaatgatta tgctcgtaag aataagttac tgaaagacaa tgaagataat ttaacagggg
    99181 aagatgttcg cgaaggctta actgcagtta tctcagttaa acacccaaat ccacagtttg
    99241 aaggacaaac caagaccaaa ttgggaaata gcgaagtggt caagattacc aatcgcctct
    99301 tcagtgaagc cttctccgat ttcctcatgg aaaatccaca gattgccaaa cgtatcgtag
    99361 aaaaaggaat tttggctgcc aaggctcgtg tggctgccaa gcgtgcgcgt gaagtcacac
    99421 gtaaaaaatc tggtttggaa atttccaacc ttccagggaa actagcagac tgttcttcta
    99481 ataaccctgc tgaaacagaa ctcttcatcg tcgaaggaga ctcagctggt ggatcagcca
    99541 aatctggtcg taaccgtgag tttcaggcta tccttccaat tcgcggtaag attttgaatg
    99601 ttgaaaaagc aagtatggat aagattctag ccaacgaaga aattcgtagt cttttcacag
    99661 ccatgggaac aggatttggc gcagaatttg atgtttcgaa agcccgttac caaaaactcg
    99721 ttttgatgac cgatgccgat gtcgatggag cccacattcg tacccttctt ttaaccttga
    99781 tttatcgtta tatgaaacca atcctagaag ctggttatgt ttatattgcc caaccaccaa
    99841 tctatggtgt caaggttgga agcgagatta aagaatatat ccagccgggt gcagatcaag
    99901 aaatcaaact ccaagaagct ttagcccgtt atagtgaagg tcgtaccaaa ccgactattc
    99961 agcgttataa ggggctaggt gaaatggacg atcatcagct gtgggaaaca accatggatc
   100021 ccgaacatcg cttgatggct agagtttctg tagatgatgc tgcagaagca gataaaatct
   100081 ttgatatgtt gatgggggat cgagtagagc ctcgtcgtga gtttatcgaa gaaaatgctg
   100141 tctatagtac acttgatgtc taaaaaatag ggagaagtag ttcccttggt ctaaaaaata
   100201 tgatataatc gttacgattg tttcaagtaa aaaaggagtt tgatatgtct aatggacaac
   100261 taatttattt aatggttgca attgcagtca ttttagttct ggcttatgta gtggcaatct
   100321 ttctacgtaa gcgaaacgag gggagattag aggcgctaga agaaagaaaa gaagaactat
   100381 acaatcttcc agtaaatgat gaagtagaag ctgtaaaaaa tatgcacttg attggacaaa
   100441 gtcaagtggc tttccgtgaa tggaatcaaa aatgggtcga tttatctctc aactcttttg
   100501 ccgatattga aaataatctc tttgaagcag aaggttataa ccattcattt cgttttctca
   100561 aggccagtca tcaaattgac caaattgaga gtcaaattac tttgattgaa gaagatattg
   100621 cggcaattcg caatgctttg gcagacttag agaagcaaga atctaaaaat agtggtcgtg
   100681 ttcttcatgc tttggattta tttgaggaac ttcagcatag agttgctgaa aattcagaac
   100741 agtatggtca agccttggat gaaattgaaa aacaattaga aaatatccaa tctgaatttt
   100801 cacaatttgt aaccttgaat tcatcgggtg accctgtgga agccgcagtg attttggata
   100861 atacagaaaa tcacattttg gccttaagtc atattgtgga tcgtgttcca gccttggtta
   100921 cgacgctttc tacagaattg ccagatcaat tacaggattt ggaatccggt tatcgtaaac
   100981 taattgatgc taattatcat tttgttgaaa cggatattga agcgcgtttc cacttgcttt
   101041 atgaagcatt caagaaaaac caagagaata ttcgtcagtt ggaattggat aatgccgaat
   101101 atgagaatgg acaggcacaa gaggaaatca atgccttgta tgatattttt actcgagaaa
   101161 ttgctgctca gaaagtagtg gaaaatctac ttgcaactct tccaacttac cttcaacata
   101221 tgaaagagaa taatacttta ttgggagaag atattgcacg tttgaacaag acctatttac
   101281 ttcctgagac agctgcaagc catgttcgtc gtattcagac agaattagag agttttgagg
   101341 cagctattgt tgaggtaact tcaaatcaag aagaaccaac ccaagcttat tcagttcttg
   101401 aagaaaatct tgaggattta caaactcaac taaaagatat tgaagatgag caaatttcag
   101461 ttagtgagcg cctgacacaa attgagaaag atgatattaa tgcacgtcaa aaggccaatg
   101521 tttatgtcaa tcgtctccat actatcaagc gatacatgga aaaacgcaat ctgccaggta
   101581 ttccacaaac tttcttgaag ttattcttta cggcaagcaa taataccgag gatttaatgg
   101641 ttgagttaga acaaaaaatg attaacattg aatctgttac ccgagttctt gaaattgcaa
   101701 cgaatgatat ggaagcttta gaaacggaaa cttataatat tgtacaatat gcaactttga
   101761 cagagcaact cttgcaatat tctaaccgct atcgctcatt tgatgaacgc attcaagaag
   101821 catttaacga agctttagat atttttgaaa aagaatttga ttatcacgct tcatttgaca
   101881 agatttctca agcattggaa gtggcagagc ctggtgtaac caatcgcttt gttacctcat
   101941 atgagaaaac acgtgaaacg attcgttttt aataaaagaa aaagatttta ttgtgtgagg
   102001 agcagaatca aatctttttc tatagttgtg gggagattta cttcattttc tcctgagatt
   102061 gagtttttac ccagccgatt tatccaccac ctcaaaacag tgttttatac tcttcgaaaa
   102121 tctcttcaaa tcacgtcagc gtcgccttac cgtactcaag tacagcctga ggctagcttc
   102181 ttagtttgct ttttgatttt catttagtat taaagtgatt tcgtcagtct tatctgcagc
   102241 ttcaaatctg tactttgagt aacttggtaa ccgtccaata acgaagtcta ttgaaaaatc
   102301 tccagactag agaactcacg gatagttcct aatctggaga tttcttattt gcacttttct
   102361 tgtacaactt tagtccacgg taaataggcc tctaaaacct ctttgtttac gagagttttc
   102421 tcgtttggaa gacattctag aagataggat agatatttct cgctatttat actagactaa
   102481 aatcaaaaag cattatacaa tagtaatatg aaatcaatta aagaagaaat ccaaaccatc
   102541 aaaacacttt taaaagactc tcgtacagct aaatatcata aacgccttca aatcgttcta
   102601 tagtaaaacg aaacaagaac aggacaaatc gatcaggaca gtcaaatcga tttctaacaa
   102661 tattttagaa gcagaggtgt actattctag tttcaatcta ctatattttt ggagtgatag
   102721 aaaagccctt catcagccaa tctacttgtt caggtgcgag agctttgaca tccttttctg
   102781 tacttagcca agtcagtttt ccgttctcaa agcgtttata tagtagccaa aatccttgac
   102841 catcccagta aagggcttta aagcggtctt tacgtccacc acaaaagaga aagacttgac
   102901 cggagaaaga atccaattca aagtgggttt taactacata ggctaatgag tctattccct
   102961 acctcatatc tgtcttacca caaacaaggt gaacttgacc taaatcactt agttgaatta
   103021 tcatagtaca atacctttcc tccgataatt attttttatc tagtatactg gaagttgggg
   103081 aattaggata gataccttgt tatgacgcgc ttacgtaact tgtaactagc tgcctagttt
   103141 gatctttgct tcttcattga ttgcagtaga tttcaaaatg ataaaaacgc ataatagtgg
   103201 gtgtagaaac tcttgttact atgcgttttg ttatggaaag acttattgga ctttctctca
   103261 aatcgagttt ttactcaatt ttcttacttg attgggattg aaattccaat taatttctct
   103321 gagtagagtg tcttgatatt ggcttcatca acagaggtct tatcaatttt acgtttcaag
   103381 aaaaattctt gaatggtttc gatttcaggc tcacgaatag cacggtgttt gtttgagatg
   103441 aggatttcat agtgaagcgg agcttgggta aaaataacat ctgtattccc tgcagaataa
   103501 acctcaacaa gggttgcatc ggtactttct agctgacttt ttacaagttg cgagtgtgag
   103561 tttgtcgtat tgataagctt cataatattt cctccggttt tctaattcta ttatagcact
   103621 ttttgaataa agtcgcttga tttatactca atgaaaataa aagagcaaac taggaagcta
   103681 gccgcaggct atacttgagt atggtaaggc gacgctgatg tggtttgaat tttattttcg
   103741 aagagtatta gtcaatctta tgctgttttt tccaagattc aatggcccat ttatggctac
   103801 cacgtttaag gtttttgata gcctcgtcaa tagggaacca ggcaatatga ttaaagtttt
   103861 ctagtggctt ttgtacttct ttgaaaggag ttgcttcata gaagtaggca ggattggagt
   103921 agtaggtatc acgatgacga gaatagaaat attcgtcagc ttgtccgtaa taggtaccaa
   103981 tttctgctgt gaaaccaagc tcttcaatca actcacgctt tagggcttcc tgatgatttt
   104041 cacctgcttc aatttctcca catggtagga accaagcacc atttggttct tgaacaagaa
   104101 caatttgttt ttgttcagga ttagggataa ctgcatatac gccatagcga gcaatatagt
   104161 ctgtattcgc ttttttctcc gaaagttggg tttgccattg cattttcctc attatctagt
   104221 atcgttatta ttatagtgaa atgaaccaaa aatagtacac aatgtggtat aatcttctta
   104281 tggcatattc aatagatttt cgtaaaaaag ttctctctta ttgtgagcga ataggtagta
   104341 taacagaagc atcacacgtt ttccaaatct cacgtaatac catttatggc tggttaaagc
   104401 taaaagagaa aacaggagag ctaaaccacc aagtaaaagg aacaaaacca agaaaagttg
   104461 atagagatag acttaaaaac tatcttactg acaatccaga cgcttatttg actgaaatag
   104521 cttctgaatt tggctgtcat ccaactacca tccactatgc gctcaaagct atgggctaca
   104581 ctcgaaaaaa gaaccacacc tactatgaac aagagccaga aaaagtagcc ttatttctta
   104641 agaattttaa tagtttaaag cacctagcac ctgtttagat tgacgaaaca ggatttgata
   104701 cttattttta tcgagaatat ggtcgctcat taaaaggtca gttaataaga ggcaaagtat
   104761 ctggaagaag atatcagagg atttctttgg ttgcaggtct aacaaatggt gaattaatcg
   104821 ctccaatgac ttacgaagag acgatgacga gcgacttttt tgaagcttgg tttcagaagt
   104881 ttctcttacc aacattaacc acaccatcgg ttattatagt aaaataaaat aagaatagga
   104941 taaatcgatc aggatagtaa aatcgaattc taacaatgtt ttagaagtag atgtgtacta
   105001 ttctagtttc aatctactat attatggata atgcaagatt ccatagaatg gggaagctag
   105061 aacttttatg cgaagagttt gggcataaac ttttacctct tcctccctac tcgcctgagt
   105121 acaatcctat tgagaaaaca tgggctcata tcaaaaagca cctcaaaaag gtattaccaa
   105181 gttgcaatac cttttacgag gctcttttgt cctgttcttg tttcaattga ctatagcaga
   105241 ttgaaataag atgagaacaa atcgattggg aaagtaaaat taatttctat aaatgtttta
   105301 gcaattgttt cgtactattt cagattcagt ctactatata tcataatgga caaagggcaa
   105361 gctgtcaaga aattacagtt attttagtaa aaaaagaagc agaaaaattt cattttctac
   105421 tccttttcta taggatttat ttttcttttt cagaactttt aacttcagct tttttggcag
   105481 atttaatctg aatgtttccc ttgctagtca taactgcttt gagatctttt tcgcttggat
   105541 tttcaaggta gtagtcagtg attgtgtcct caatatagtc ttgaatagtc cgacgaagtg
   105601 ggcgtgctcc catttttgga tcataaccta ggtcaaccaa ctttttcttg accttatcag
   105661 ttacatccaa acgaatgttg ttgctagaga ggcgcttgtt aacatctgct agcatgagct
   105721 cgacaatctg aaggaggtta tccttgctga gagccttaaa ttcgataatg ccatcaaaac
   105781 ggttcataaa ctctgggcta aagaagttac cgagttcacc gaggacagaa ttggtacgtc
   105841 cttctctagc agcaccaaat ccaacgctag cttcggtctt tcctgtacct gcatttgagg
   105901 tcatgataat gatggcatcc ttgaagctaa cggtgcgtcc ttgcccgtct gtcaaacgac
   105961 catcgtccaa gacttgaaga aacatgtgca taacatctgg gtgagctttt tccacttcat
   106021 cgagaaggat gagagaatat ggattgtggc gaactttttc agttaattga ccagcctcat
   106081 catagccaac ataacctgga ggggcgccga ccaacttagc cacactatgt ttttccatgt
   106141 attcactcat atcaaagcga atcatactat cagcagaacc aaaaagttcg atagccagtt
   106201 gtttggaaag ttctgtctta ccgacaccag ttggcccaac gaagaggaag cttccgattg
   106261 ggcggttagg ggtaccaagt ccgacacgat tacggcgaat agccttggca atcttatcga
   106321 ctgcatcatc ttggccaata acatgagact tgagatcttc ggctagatgg atgagttgag
   106381 attgttcttt ctctttcaaa tcaccaacag ggatattggt tttctgctcg ataatgtgct
   106441 caatagtttt ctcgctgatg ataggagtat cctggtctgt gatctttttc ttttgcattt
   106501 ccttatactt ggcaatctgg tcgcggaagt aggccgcctt ctcaaaatct tcttctcgtg
   106561 tagcttgaga cttgagattt tcagcctcaa tcaagcgctg atcaattact ttaggatcca
   106621 caaaattcaa ggtcaagttc atcttagaac cagcttcatc taggaggtca atggccttgt
   106681 caggcaagaa gcgatcttgg atgtagcgat tggaaagagt tgcagctgct tcaatcgcag
   106741 catctgtata ttgaacgtgg tggtaatctt cgtatttctt ttgaatccct ttgagaatag
   106801 tgattgtttc gtccaccgtt ggttcatcga ctttaacagg ctgcatacga cgctcgaggg
   106861 cagcatcctt ttcaatgata cggtattcat tgagggtagt agcaccgact agttgcagtt
   106921 ctccacgagc aagggctggc ttgaggatat ttcctgcgtc catattacca tcactcgcag
   106981 aaccagcacc aacaatttca tggatttcat cgataaagag gatgatgtct tcacgtttgc
   107041 gaatttcttc catgagtttt tgcatgcgtt cttcaaattg tcctcgaatc cccgttcctt
   107101 gaactaagct aaccacatcc agacggatga cttgtttacc ttggagttta tgtggcacat
   107161 cgccatcgac aattttctga gctagacctt cgacaacggc cgtttttccg acaccaggtt
   107221 caccgataag gacaggatta ttcttggttc tacgattgag aatctcgatg acacggataa
   107281 tctcatcgtc gcgcccaata acggggtcaa tgtctccacg acgggcaatt tcagttacat
   107341 taataccaaa ttctttcagc aggccttttt cttggctagg tggcggagtt tgagcagatc
   107401 cacgattttg ggaaccataa ccgccgtttc caccgtaacc tccacctgat tgggttgggg
   107461 gaataggagg agtattgcta gaaggtctga aattgtttag atcattgaag aaatcaccaa
   107521 agggatcgaa gtcacgattg ttcagatccg tcataccttt gaagaggcta ttgttaggat
   107581 ctgttttgat aatcttatag cagttttgac agaggtcaat ttgtttttgt tttccattga
   107641 gattggtgta aagatgaatt gttgagtcgt taattttaca gttttgacaa agcatacatc
   107701 tacctcattt ctttctttag cctgacttgt ttaaaggtca aaaatagtca aattctatac
   107761 tctcattata acaggattgg ggtgtaaagc aagtaaaaag attgaagctt tgagaagttg
   107821 ttacaatgaa aatttttgtg aatttggact ataaaaaaat cctatttgtg agacaaaaag
   107881 gattttactt agacatgcag ggacaatccc agcttgtttt agattagtag agaagttcgt
   107941 aaatttccat tgcgattaag tcaatgctat caaacgtata cgtttcgcga tcttctacgt
   108001 cacgaagggt aaagattggg ccgttttctt cgtcgtggct gtacgcaact tctgcaacaa
   108061 caactccttc gcgttcaaaa ttacgtttta aatttccgcc atcgtttgcc attgcttcaa
   108121 ggcggttgat gattctaacc aaatgtgatt ccattttgat tctccttcat ttcttatcgt
   108181 tactatttta ccataaagga ggccaacttg actagaaaaa actaagattt ctcgctaatt
   108241 ctgctagttt aaaggttttt aaataaattg gataaaaaat ttaaatttta attcaaaaca
   108301 tgttataatc atacagtatt ctattttaga aagcagtgtg actatgaatt tttctttttt
   108361 acctaagtat ttaccttatt ttaactatgg ggctgttgtg acgattctta tttctatctg
   108421 tgttatcttt ttgggaacta ttttgggtgt tgtcttggct tttgggcaac gttcaaagtt
   108481 taaaccgctt gtttggttgg ccaacttgta cgtttggatt ttccgtggga caccgatgat
   108541 ggttcaaatt atgattgcct ttgctcttat gcatatcaat gctccgacta ttcagattgg
   108601 aattttaggt gttgattttt cgcgtctgat tccagggatt ttgattatct ctatgaatag
   108661 tggtgcttat gtttcggaga ctgttcgtgc cggaatcaat gcggttccaa aaggtcagct
   108721 agaggcggct tattcgctag ggattcgtcc taaaaatgcg atgcgttatg tgattttgcc
   108781 acaagcagtc aaaaatatct tgccagcatt ggggaacgaa tttatcacca ttatcaagga
   108841 cagctccctc ttatcagcta ttggggtcat ggagttgtgg aatggggcta caacagtttc
   108901 tacaacaacc tatctacctt taacaccact tttatttgca gcattttact acttgattat
   108961 gacctctatt ctgacagtag ccttgaaagc ttttgaaaaa catatgggac aaggagataa
   109021 gaaataatga cagaaacctt gataaaaatt gaaaatttac ataaatcttt tggaaagaat
   109081 gaagtattga agggcatcaa cctcgagatt aaaagaggag aagttgtcgt tatcatcggt
   109141 ccttcaggga gtgggaaatc taccttgctt cgctctatga atttgttgga ggaagcaacc
   109201 aaggggaagc ttatctttga gggagtcgat attacggaca agaagaatga cctgtttgcc
   109261 atgcgtgaga agatgggcat ggttttccaa caatttaacc tctttcctaa tatgactgtg
   109321 atggaaaata ttaccttgtc acctatcaag actaaaggtg aaagcaggga agttgctgag
   109381 aagagagccc aagagctttt ggaaaaagtt ggtttgccag ataaggcaga cgcttatcca
   109441 cagagtctgt cgggtgggca acaacaacgg attgccatcg cgcgtgggtt ggctatggaa
   109501 ccagatgttt tgctctttga cgaaccaact tcagccttgg atcctgaaat ggtaggtgag
   109561 gtattggctg ttatgcaaga ccttgccaag tcagggatga ctatggttat cgtaacacat
   109621 gagatgggat ttgcccgtga ggtggcagat cgtgttatct ttatggcaga cggtgtggtt
   109681 gttgaagatg ggacacctga gcagattttt gaacaaaccc aagaacaacg gactaaagat
   109741 ttcttgagta aggttttata atctatttta aaatttcaag acaagattag tgaaaagttc
   109801 aaccagagct ttttcttata gtttgaaact ataggataac ctaggaaaga agtgttagag
   109861 ggcactagca gtttttggta taatggaaga tatttgaaag aaaagagaag tgatatgaca
   109921 cagattattg atgggaaagc tttagcggcc aaattgcagg ggcagttggc tgaaaagact
   109981 gcaaaattaa aggaagaaac agctctagtg cctggtttgg tagtgatttt ggttggggat
   110041 aatccagcca gccaagtcta cgttcgcaac aaggagaggt cagctcttgc ggctggttcc
   110101 cgtagcgaag tagtgcgagt tccagagacc attactcaag aggaattgtt agacctgatt
   110161 gctaaataca atcaggatcc agcttggcat gggattttgg ttcagttgcc attaccaaaa
   110221 cacattgatg aagaggcggt tctattggct attgacccag aaaaggatgt ggatggtttc
   110281 catcctctaa atatgggacg cctttggtct ggacatccag tcatgattcc atcaacacct
   110341 gcaggaatta tggaaatgtt tcatgaatat gggattgaat tagaaggtaa aaatgcggtt
   110401 gtcatcggtc gttctaatat cgttggaaaa cccatggctc agcttctttt ggccaagaat
   110461 gcaacagtga ctttgaccca ctcacgcacc cataatcttg ctaaggtggc tgctaaagca
   110521 gatattctgg tggtcgcaat cggtcgtgcc aagtttgtga ctgctgactt tgtcaaacca
   110581 ggtgcggtag tcattgacgt tgggatgaat cgtgatgaaa atggtaagct ctgtggggat
   110641 gtggattatg aggcagttgc cccacttgct agctatatta cgccagtccc tggaggtgtc
   110701 ggccctatga ccattactat gctgatggag caaacttatc aagcagcact tcggacattg
   110761 gatagaaaat aagagaaaaa tcgctgaaga gagtgtattt tctatagcta tatttaaaat
   110821 ggcagaaatg aatattaaat tttagatata agattacaaa aggaggtctg cgcctccttt
   110881 ttgttgtata atggagtgag gtgattagat gattttaaaa atttataata gggaatatag
   110941 tttacaatgg gatggaatat actacctagc actaattgat tatccaaata ttcaagagtg
   111001 ggaattagaa aaaattgcta aatttatagc ttacgaaaaa cttcataaac gtcaaacaag
   111061 tattgagtgt gctgattctt gtttaaaaaa agaaatttta gattacatct gtcagcatcc
   111121 ctttctgcca ccatttaccc ctacagataa aagagtagcc tcgacttatg atctacataa
   111181 gaggttagtg acttcagact actgtagtca tactacgact atagatgcag cgatttctat
   111241 ctttaaaaca ggtcagctct tatctgctgt gaaagccttt aggcgagatg ctgaagagtt
   111301 ggttttggat agtagaaatg ctgcatcgga tccgatagat tattttgatt atgtcatgtt
   111361 agggtggtca aatacaagtt ctggttatcg attagcgatg gagcgtttat taggtcgagc
   111421 tccttcagag aaagaattac aagacaagtt tattcctgga gtgagttttc attttatcta
   111481 tacagatttg attaaagtta ctggttatat ttttgatggc taccatgttg caaaaattaa
   111541 ggacatgttg aatttattta gtgagttgta tatttgtatt attccaactc ataataagag
   111601 ccaatttgaa aatattattc caactaaaat acaagatagg gtgcattatc ttgactatgc
   111661 tggagaagac ttagaagagt ggactaagaa agtctatcaa gttgttttaa aacaatcaga
   111721 taaaggatag ttgaggaaga acgatgaaag tgattgatca agccttacta gaaaaagtta
   111781 ttattgaacg ttctcgtact agtcataaag gagactatgg ccgtctgctg tttcttggtg
   111841 gaacttatcc ttatggtggt gccatcatca tggctgcttt ggcagctgta aaaagcggtg
   111901 caggattggt gaccgttgga acagataggg aaaatattcc agccctgcac agccatttac
   111961 ctgaggctat ggccttttct cttcaagacc agcagttgtt aaaagagcaa ttggagaagg
   112021 cagaagttgt cttgctgggg ccgggtttac gagacgatgc ttttggagaa gatctagtta
   112081 aacaggtctt tgctggctta agacaaaatc agattttgat tgtagacgga ggtgccttga
   112141 ccattcttgc taggacaagt ttgtcatttt cctcaagcca gcttatccta actcctcacc
   112201 aaaaagaatg ggaaaaatta tctggaatta cgattgaaaa gcaaaaggaa gatgcaacgg
   112261 ctagtgccct aacttccttc cctcaaggaa caattttggt ggagaaaggt tcagctactc
   112321 gtatttggca agctggccaa tcagattatt accagttaca ggttggcggt ccctatcagg
   112381 cgactggggg aatgggagat acgcttgctg ggatgattgc aggatttgca ggccagttta
   112441 agcaagctag tctttacgaa cgtgtggcag tagcgaccca tcttcattca gccatagccc
   112501 aagaactagc tcaagaacag tatgtggttt tgccaacgga gattagtaat tgtcttccta
   112561 aagtaatgaa aagatatgtc taaaatagtt agacaaaaaa tattgataat ttgtatcatt
   112621 attcttaatt cacaaaaaac gaacgtttag tattcttctc gctaagaaac taaatttgtt
   112681 cgttttttta ctcttgtaaa tctatttttg ttagagttga tttggtttac atccgtactt
   112741 aaagtgattt gtcagagttc tgcttttatt aaaaaaattt aatttcaagg ataaataagc
   112801 agtattctaa aggtactttt agatgaaata aaagccttta catggtataa tagaggtagc
   112861 tctttaatgg aggtgtttga gtggaaaatc tgaagaaaat ggcaggtatc aaggctgctg
   112921 agtttgtcaa ggatggaatg gtcgttggac ttggaacagg ctcgactgcc tattattttg
   112981 tcgaagaaat cggtcgtcgt atcaaggaag aaggattgca gattatagct gtaacgactt
   113041 ctagtgtgac cactaaacag gcagaaggcc ttaatatccc actcaaatct attgaccaag
   113101 tagactttgt cgatgtgaca gttgatggcg cagatgaagt ggatagtcag tttaatggaa
   113161 tcaaaggtgg tggtggtgct cttctgatgg agaaggttgt tgcgacacca tcaaaagaat
   113221 acatttgggt ggtggatgaa agcaagctgg tcgaaaaact aggtgctttt aaattgccag
   113281 tagaagtggt tcagtatggt gcagaacagg tctttcgtcg ttttgaacga gctggctaca
   113341 aaccaagttt ccgtgaaaaa gatggccaac gttttgtgac ggatatgcag aattttatca
   113401 ttgacctcgc cttggatgtc attgaaaatc caattgcttt tggacaagaa ttggaccata
   113461 tcgttggtgt tgtggagcac ggtttattca accaaatggt ggataaggta atcgttgctg
   113521 gacgagatgg agttcagatt ttaacttcaa aaaaaggaaa atagaagggg gcataagatg
   113581 tctaaattta atcgtattca tttggtggta ctggattctg taggaatcgg tgcagcacca
   113641 gatgctaata actttgtcaa tgcaggggtt ccagatggtg cctctgacac actgggacac
   113701 atttcaaaaa cagttggttt gaatgtccca aacatggcta aaatcggtct tggaaatatt
   113761 cctcgtgaaa ctcctcttaa gactgtaccg gcagaaagca atccaactgg atatgcgaca
   113821 aaattggaag aagtgtccct tggtaaggac accatgactg ggcactggga aatcatggga
   113881 ctcaacatta cggagccttt cgatactttc tggaacggat tcccagaaga aatcctgaca
   113941 aaaatcgaag aattttcagg acgtaaggtc attcgtgaag ctaacaaacc ttactcagga
   114001 acagccgtta tcgatgattt tggaccacgt cagatggaaa ctggagagtt gattatctat
   114061 acttcagctg accctgtttt gcaaattgct gctcacgaag acatcattcc tctggatgaa
   114121 ttgtaccgta tctgtgaata cgctcgttcg attacccttg agcgtcctgc ccttcttggt
   114181 cgcatcattg cccgtccata tgttggtgag ccaggtaact tcactcgtac ggcaaaccgt
   114241 cgtgacttgg ctgtatctcc atttgcccca actgttttgg ataaattgaa tgaggctggt
   114301 atcgatactt atgctgttgg taaaatcaac gatatcttta acggtgccgg tatcaaccac
   114361 gacatgggcc ataacaagtc aaacagccat ggaattgata cactattgaa gactatggga
   114421 cttgctgagt ttgaaaaagg attctcattc acaaacctgg ttgactttga tgccctttac
   114481 ggccaccgtc gtaatgctca cggttaccgt gattgcttgc atgagtttga tgaacgctta
   114541 cctgaaatta tcgcagccat gcgagagaac gaccttctct tgattactgc ggaccacggg
   114601 aacgacccaa cttacgcagg aacagaccac actcgcgaat atatcccact tttggcttac
   114661 agtcctgctt ttaaaggaaa tggtgtcatt ccagtaggac attttgcaga tatttcagcg
   114721 actgttgccg ataactttgg tgtggaaact gccatgattg gggaaagttt cttagataaa
   114781 ttggtataag atgacatgct atgctttgct ggtgagaggc atcaatgttg gtggtaagaa
   114841 taaggtcgtc atggctgagc ttcggcaaga attgacagag ttgggaattg aaaaggttga
   114901 aagctacatc aacagtggca atgttttctt tacttcgaca gttcccaaag cccgattgat
   114961 tgaaaaatta gagactttct ttgcagtcca ttatccattt attcagagtt tttccctact
   115021 gagtcaagaa gactatgaag cagaagtgga gaatctacca gcttggtgga acgaagactt
   115081 ggcacgaaaa gacgttctct tttacactga gcttttggat gtggagcaag tcatcacgac
   115141 agttgagagt ttagagctga aagatgaggt cgttcatttt ggaaaacttg gtattttctg
   115201 ggggaaattc tctgaagaat cctaccctaa gactgcctat cacaagtact tgctcaagat
   115261 gcctttctat tgccacatta ccattcgcaa tgcaaaaacc tttgacaaaa tcggtcaaat
   115321 gctaaaaaat aataaaggag acacacaatg acatttttaa acaaaatcca tgaaactgct
   115381 actttcctga aagaaaaggg aatccaaacg cctgagttcg gtctaatcct tggatcagga
   115441 cttggagaac tggcagaaga aatcgaaaat ccagttgtag tagactatgc ggatattcca
   115501 aactggggcc gttcaacagt agttggtcac gctggtaaat tggtatatgg tgaccttgca
   115561 ggtcgcaagg tcttagctct tcaagggcgt ttccatttct acgaagggaa ccctctggaa
   115621 gttgtgactt tcccagtacg tgtcatgaaa gttcttggat gtgaaggtgt cattgtaacc
   115681 aatgcagctg gtggtattgg ttatggccct ggtactttga tggctatttc agatcatatc
   115741 aatatgacgg ggcaaaatcc attgatgggt gaaaacttgg atgactttgg tccacgtttc
   115801 cctgatatgt ctaaagccta cacaccagaa taccgtgcta ctgcccatca agtggctaag
   115861 aaacttggta tcaagcttga tgaaggtgtc tatatcggtg taactggtcc gacttatgaa
   115921 acacctgcag agattcgtgc ctataagaca ctgggagcag atgcagttgg tatgtctacg
   115981 gttcctgaag tgatcgtggc agcccactct ggcttgaaag ttctgggaat ttcatgtatt
   116041 actaactttg cggctggttt ccaagaagaa ctcaaccacg aagaagttgt ggaagtaacc
   116101 gaacgtgtca aaggtgactt caagggcttg cttaaagcga ttcttgctga attgtaagaa
   116161 aaaagattta aaagggggaa tacctctacc ttttcatgat tgactggcta ttcggaacaa
   116221 ataagaaaca taggtagact atgggtttct tcctactctt gtaactgaaa gagtctgata
   116281 gttagcattg tgaaagacaa gattctagga tactagcatt agcttcctac caagcagact
   116341 aggatgataa ggaaagataa gaatgaattt actttctgaa tttcttagcc ttgtcctata
   116401 taggggacaa ggagatttcg cttgagtctg cttacaaata aacgaaaaga aagataaaga
   116461 ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaaattaaa tatcggggtt
   116521 gtatctgttg cagtcggctt tgatttctag ctccagctgg aatttcagcc aatgaagtaa
   116581 agcaagatgt aacatctgaa gtggtaatag gtgtactaga ttctaaggag gaattgaaag
   116641 agtcagaaaa tgatgctcca aaactagaaa ctcctcttag agaggagcca agactagctc
   116701 ctcaaacgct tctggaagca agtgaagtcc ttgaaaacaa aagggaagag tcaaaagtag
   116761 agataacaga gccagctcaa gcggatgata tccgcaaggt tgttggggaa ttagccaagg
   116821 atataagtat tactaagttg tatatgacag gtcattctct tggatgctac ctagctcaga
   116881 ttgcagaggt tgaagcttac caaaaatatc ctgattttta taaccatgta ttgaggaaag
   116941 tgacaacttt cagtgctcct aaagtcatta cttccagaac tgtttggaat gctaagaatg
   117001 gtttctggga tgttggtttg gaaagtcgta aattagctgt tagtggaaaa ttaagcatta
   117061 tgtggttgat aatgacaatg ttgtgactcc cttgattcat aataatcgtg atattgttac
   117121 atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa gtccaatgaa
   117181 tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg gttatcgtga
   117241 tccgaaattg gataaagtgc gattctttaa gaaacaggct ctgcctcgat cttctagtca
   117301 accaagcgct gaaccaatgg aaaatattgc cttaggaaaa caggttactc aaagttcgac
   117361 agttttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta actatggtca
   117421 caattctgtc actcatacaa acttccaatc taagccttgg tggcaagtag atttggctaa
   117481 agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc aggatagatt
   117541 ggcaaacttt gatgtcattc ttttagacag ttctggtaaa gaaattgagt aaaaacgtat
   117601 aacatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaag tgcgctatgt
   117661 tcggattgag ctagaaggct ataatgccct cagtcttgca gaagttgaag ttttccgctt
   117721 tatagctacg aatgctgaaa cggcgacaca agtttctaag ccagttcaac caatcagtca
   117781 gactcctgtg aaagataaaa cattgacaat tcaacacagt ggagcttaca ttgcccgcta
   117841 ctccataact tgggaagaag ttccagtaga taaagatgga aaccaagttg ttcgtagtca
   117901 ttcttgggaa ggaaacggtt gcaaccagac tgcaggtttt gtcctcaact tcccaatcaa
   117961 agaaaatatg agaaatctgc gagttaagat tgagaaaaag acgggcctac tatggaatag
   118021 atggcaaaca atctatgaaa acagaccaat tttagctcaa ccccaccgta aaattaccca
   118081 ttggggtacg acattgaatt ccaaggtgag tgacgatgat gtcttgtaat ctgatggtac
   118141 aatgacagtt agtttgtcta gtttataaga aagtactatc tgagcttgaa tagaactcag
   118201 gtagctctct gtgaaagaac aaaatt
//
LOCUS       DAVLGK010000002        79344 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLGK010000002 DAVLGK010000000
VERSION     DAVLGK010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.002"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(255..1016)
                     /locus_tag="VXE01_000130"
     CDS             complement(255..1016)
                     /locus_tag="VXE01_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0749127.1"
                     /translation="MDNLYLVKDDSQLAAFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSSFNAATQIIRESAVPAYTNNRRMVMTPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEYFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTIDKLVENLG
                     SVQAVFDSYHLWANTDKTLPLLNWFVQQKLIEKEI"
     gene            complement(1289..2131)
                     /locus_tag="VXE01_000131"
     CDS             complement(1289..2131)
                     /locus_tag="VXE01_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV0749128.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(2245..3636)
                     /locus_tag="VXE01_000132"
     CDS             complement(2245..3636)
                     /locus_tag="VXE01_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV0749129.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(3871..4248)
                     /locus_tag="VXE01_000133"
     CDS             complement(3871..4248)
                     /locus_tag="VXE01_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0749130.1"
                     /translation="MLCQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGTQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLASHSFIVK"
     gene            4373..5350
                     /locus_tag="VXE01_000134"
     CDS             4373..5350
                     /locus_tag="VXE01_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0749131.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            5347..6429
                     /locus_tag="VXE01_000135"
     CDS             5347..6429
                     /locus_tag="VXE01_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0749132.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(6493..7514)
                     /locus_tag="VXE01_000136"
                     /pseudo
     CDS             complement(6493..7514)
                     /locus_tag="VXE01_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(7898..9094)
                     /gene="tuf"
                     /locus_tag="VXE01_000137"
     CDS             complement(7898..9094)
                     /gene="tuf"
                     /locus_tag="VXE01_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0749133.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(10027..10896)
                     /locus_tag="VXE01_000138"
     CDS             complement(10027..10896)
                     /locus_tag="VXE01_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0749134.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(11119..11639)
                     /locus_tag="VXE01_000139"
                     /pseudo
     CDS             complement(11119..11639)
                     /locus_tag="VXE01_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(11597..12703)
                     /locus_tag="VXE01_000140"
     CDS             complement(11597..12703)
                     /locus_tag="VXE01_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV0749135.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSYRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(12814..13068)
                     /locus_tag="VXE01_000141"
     CDS             complement(12814..13068)
                     /locus_tag="VXE01_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749136.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(13426..13959)
                     /locus_tag="VXE01_000142"
     CDS             complement(13426..13959)
                     /locus_tag="VXE01_000142"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0749137.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(13946..14272)
                     /locus_tag="VXE01_000143"
     CDS             complement(13946..14272)
                     /locus_tag="VXE01_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0749138.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QEHIERKKRVVKNRKIPLEELKTFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDEL"
     gene            14506..16224
                     /locus_tag="VXE01_000144"
     CDS             14506..16224
                     /locus_tag="VXE01_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV0749139.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            16335..16682
                     /locus_tag="VXE01_000145"
     CDS             16335..16682
                     /locus_tag="VXE01_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0749140.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     SGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(16961..17797)
                     /locus_tag="VXE01_000146"
     CDS             complement(16961..17797)
                     /locus_tag="VXE01_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0749141.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(17810..18439)
                     /locus_tag="VXE01_000147"
     CDS             complement(17810..18439)
                     /locus_tag="VXE01_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0749142.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(18449..19090)
                     /locus_tag="VXE01_000148"
     CDS             complement(18449..19090)
                     /locus_tag="VXE01_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0749143.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(19236..20465)
                     /locus_tag="VXE01_000149"
     CDS             complement(19236..20465)
                     /locus_tag="VXE01_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV0749144.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSNLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(20455..21621)
                     /locus_tag="VXE01_000150"
     CDS             complement(20455..21621)
                     /locus_tag="VXE01_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0749145.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            21765..22778
                     /locus_tag="VXE01_000151"
     CDS             21765..22778
                     /locus_tag="VXE01_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV0749146.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(22823..23242)
                     /locus_tag="VXE01_000152"
     CDS             complement(22823..23242)
                     /locus_tag="VXE01_000152"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV0749147.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(23253..24659)
                     /gene="atpD"
                     /locus_tag="VXE01_000153"
     CDS             complement(23253..24659)
                     /gene="atpD"
                     /locus_tag="VXE01_000153"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV0749148.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(24745..25623)
                     /locus_tag="VXE01_000154"
     CDS             complement(24745..25623)
                     /locus_tag="VXE01_000154"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV0749149.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(25639..27144)
                     /locus_tag="VXE01_000155"
     CDS             complement(25639..27144)
                     /locus_tag="VXE01_000155"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV0749150.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENAMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(27159..27695)
                     /locus_tag="VXE01_000156"
     CDS             complement(27159..27695)
                     /locus_tag="VXE01_000156"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV0749151.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(27695..28189)
                     /gene="atpF"
                     /locus_tag="VXE01_000157"
     CDS             complement(27695..28189)
                     /gene="atpF"
                     /locus_tag="VXE01_000157"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV0749152.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(28203..28919)
                     /gene="atpB"
                     /locus_tag="VXE01_000158"
     CDS             complement(28203..28919)
                     /gene="atpB"
                     /locus_tag="VXE01_000158"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV0749153.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLPYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(28954..29154)
                     /locus_tag="VXE01_000159"
     CDS             complement(28954..29154)
                     /locus_tag="VXE01_000159"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV0749154.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(29229..30236)
                     /locus_tag="VXE01_000160"
                     /pseudo
     CDS             complement(29229..30236)
                     /locus_tag="VXE01_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(30742..31092)
                     /locus_tag="VXE01_000161"
     CDS             complement(30742..31092)
                     /locus_tag="VXE01_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0749155.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSL"
     gene            31220..31297
                     /locus_tag="VXE01_000162"
                     /pseudo
     CDS             31220..31297
                     /locus_tag="VXE01_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(31465..31947)
                     /gene="greA"
                     /locus_tag="VXE01_000163"
     CDS             complement(31465..31947)
                     /gene="greA"
                     /locus_tag="VXE01_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV0749156.1"
                     /translation="MAEKTYPMPLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(32018..33673)
                     /gene="mltG"
                     /locus_tag="VXE01_000164"
     CDS             complement(32018..33673)
                     /gene="mltG"
                     /locus_tag="VXE01_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV0749157.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVSTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(33754..34248)
                     /locus_tag="VXE01_000165"
     CDS             complement(33754..34248)
                     /locus_tag="VXE01_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0749158.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(34245..34709)
                     /locus_tag="VXE01_000166"
     CDS             complement(34245..34709)
                     /locus_tag="VXE01_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0749159.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEMAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(34719..36053)
                     /locus_tag="VXE01_000167"
     CDS             complement(34719..36053)
                     /locus_tag="VXE01_000167"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV0749160.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEVEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(36064..36681)
                     /locus_tag="VXE01_000168"
     CDS             complement(36064..36681)
                     /locus_tag="VXE01_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0749161.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(36729..39827)
                     /locus_tag="VXE01_000169"
     CDS             complement(36729..39827)
                     /locus_tag="VXE01_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0749162.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNMAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(39920..41086)
                     /locus_tag="VXE01_000170"
     CDS             complement(39920..41086)
                     /locus_tag="VXE01_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0749163.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(41094..42188)
                     /locus_tag="VXE01_000171"
     CDS             complement(41094..42188)
                     /locus_tag="VXE01_000171"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0749164.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(42345..42890)
                     /locus_tag="VXE01_000172"
     CDS             complement(42345..42890)
                     /locus_tag="VXE01_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749165.1"
                     /translation="MEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLV
                     IDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEILI
                     FDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLEEGKITGSGT
                     HKELLENHERYARFVQEQMIE"
     gene            complement(42926..43465)
                     /locus_tag="VXE01_000173"
     CDS             complement(42926..43465)
                     /locus_tag="VXE01_000173"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749166.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALDNLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKG
                     QKLLLLDHLDQENQRLCVC"
     gene            complement(43474..44019)
                     /locus_tag="VXE01_000174"
     CDS             complement(43474..44019)
                     /locus_tag="VXE01_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749167.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDMSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEI"
     gene            complement(44191..46149)
                     /locus_tag="VXE01_000175"
     CDS             complement(44191..46149)
                     /locus_tag="VXE01_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0749168.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(46352..47974)
                     /locus_tag="VXE01_000176"
     CDS             complement(46352..47974)
                     /locus_tag="VXE01_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0749169.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            48080..49525
                     /locus_tag="VXE01_000177"
     CDS             48080..49525
                     /locus_tag="VXE01_000177"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV0749170.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLREQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QQPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(49571..49753)
                     /locus_tag="VXE01_000178"
     CDS             complement(49571..49753)
                     /locus_tag="VXE01_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0749171.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGLKNVFTK"
     gene            complement(49854..50449)
                     /locus_tag="VXE01_000179"
                     /pseudo
     CDS             complement(49854..50449)
                     /locus_tag="VXE01_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            complement(50486..50998)
                     /locus_tag="VXE01_000180"
     CDS             complement(50486..50998)
                     /locus_tag="VXE01_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV0749172.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(51085..52020)
                     /locus_tag="VXE01_000181"
     CDS             complement(51085..52020)
                     /locus_tag="VXE01_000181"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV0749173.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(52091..52390)
                     /locus_tag="VXE01_000182"
     CDS             complement(52091..52390)
                     /locus_tag="VXE01_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV0749174.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(52380..53129)
                     /locus_tag="VXE01_000183"
     CDS             complement(52380..53129)
                     /locus_tag="VXE01_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV0749175.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(53183..53542)
                     /locus_tag="VXE01_000184"
     CDS             complement(53183..53542)
                     /locus_tag="VXE01_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV0749176.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(53544..54944)
                     /locus_tag="VXE01_000185"
     CDS             complement(53544..54944)
                     /locus_tag="VXE01_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV0749177.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(55239..55478)
                     /locus_tag="VXE01_000186"
     CDS             complement(55239..55478)
                     /locus_tag="VXE01_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV0749178.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(55510..55980)
                     /gene="ssbA"
                     /locus_tag="VXE01_000187"
     CDS             complement(55510..55980)
                     /gene="ssbA"
                     /locus_tag="VXE01_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV0749179.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(55992..56282)
                     /locus_tag="VXE01_000188"
     CDS             complement(55992..56282)
                     /locus_tag="VXE01_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV0749180.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(56435..57781)
                     /gene="asnS"
                     /locus_tag="VXE01_000189"
     CDS             complement(56435..57781)
                     /gene="asnS"
                     /locus_tag="VXE01_000189"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV0749181.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(57797..58162)
                     /locus_tag="VXE01_000190"
     CDS             complement(57797..58162)
                     /locus_tag="VXE01_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0749182.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGIEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(58155..59342)
                     /locus_tag="VXE01_000191"
     CDS             complement(58155..59342)
                     /locus_tag="VXE01_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0749183.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVAPNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEKRLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(59339..59827)
                     /locus_tag="VXE01_000192"
     CDS             complement(59339..59827)
                     /locus_tag="VXE01_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV0749184.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            60148..60696
                     /locus_tag="VXE01_000193"
     CDS             60148..60696
                     /locus_tag="VXE01_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0749185.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLAADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGASALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLIEAIK"
     gene            complement(60973..61701)
                     /gene="yaaA"
                     /locus_tag="VXE01_000194"
     CDS             complement(60973..61701)
                     /gene="yaaA"
                     /locus_tag="VXE01_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV0749186.1"
                     /translation="MKILIPTAKEMNTDLPSIEAISLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTTQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(61780..61944)
                     /locus_tag="VXE01_000195"
     CDS             complement(61780..61944)
                     /locus_tag="VXE01_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV0749187.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(62011..63606)
                     /locus_tag="VXE01_000196"
     CDS             complement(62011..63606)
                     /locus_tag="VXE01_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749188.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            complement(63618..64028)
                     /locus_tag="VXE01_000197"
     CDS             complement(63618..64028)
                     /locus_tag="VXE01_000197"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0749189.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(64144..64935)
                     /gene="yghU"
                     /locus_tag="VXE01_000198"
     CDS             complement(64144..64935)
                     /gene="yghU"
                     /locus_tag="VXE01_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV0749190.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(64948..67644)
                     /locus_tag="VXE01_000199"
     CDS             complement(64948..67644)
                     /locus_tag="VXE01_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0749191.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEDHVLTGAELNELSDEDFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            67948..69132
                     /gene="mntE"
                     /locus_tag="VXE01_000200"
     CDS             67948..69132
                     /gene="mntE"
                     /locus_tag="VXE01_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV0749192.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(69275..71146)
                     /locus_tag="VXE01_000201"
     CDS             complement(69275..71146)
                     /locus_tag="VXE01_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0749193.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(71143..72327)
                     /locus_tag="VXE01_000202"
     CDS             complement(71143..72327)
                     /locus_tag="VXE01_000202"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV0749194.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKDIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(72339..73106)
                     /locus_tag="VXE01_000203"
     CDS             complement(72339..73106)
                     /locus_tag="VXE01_000203"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV0749195.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLACFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRTQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEIRESIQQGAADEEELITGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(73383..74231)
                     /locus_tag="VXE01_000204"
     CDS             complement(73383..74231)
                     /locus_tag="VXE01_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0749196.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(74233..74607)
                     /locus_tag="VXE01_000205"
     CDS             complement(74233..74607)
                     /locus_tag="VXE01_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV0749197.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(74681..76033)
                     /locus_tag="VXE01_000206"
     CDS             complement(74681..76033)
                     /locus_tag="VXE01_000206"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV0749198.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKKTGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(76057..76836)
                     /locus_tag="VXE01_000207"
     CDS             complement(76057..76836)
                     /locus_tag="VXE01_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV0749199.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(76823..77680)
                     /locus_tag="VXE01_000208"
     CDS             complement(76823..77680)
                     /locus_tag="VXE01_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV0749200.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERW
                     LGGWKHEKK"
     gene            77816..78784
                     /locus_tag="VXE01_000209"
     CDS             77816..78784
                     /locus_tag="VXE01_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0749201.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPGQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(79037..>79344)
                     /gene="lytA"
                     /locus_tag="VXE01_000210"
     CDS             complement(79037..>79344)
                     /gene="lytA"
                     /locus_tag="VXE01_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0749202.1"
                     /translation="DRWKKHTDGNWYYFDQSGEMATGWQKIADKWYYFDVEGAMKTGW
                     VKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
BASE COUNT        23167 a        17688 c        14662 g        23827 t
ORIGIN      
        1 ggcagtccga ctgtaaggag gtttctgcca ctgatgcagt gaaatgttaa tttcttagac
       61 attgtttact cctttttata taaattactt gcgacacgag tctgcctcgt cgatcatacg
      121 aggcaagacg agttagtact gcgtctagct caggcactct agtgctgagc gtggggtagc
      181 ccgactgtaa ggaggtctct gccactgacg cagtgaaatg ttaatttctt agacattgtt
      241 tactccttta gtttttatat ctctttttca attaatttct gctgaacaaa ccaatttaac
      301 aagggaagag ttttatctgt atttgcccat aaatgataag aatcgaagac cgcttgtaca
      361 ctacctagat tttctaccaa cttatctatt gtcaaaaaac tacgccagta ttcgtaaaaa
      421 atacttgcat aattcttatc ataagtcgaa gaaccaaaat cattcaatga atgccaacca
      481 tacttcttct gaaaaagttc tacaagagac tgattacaaa ttttttccgc ttgaaattcc
      541 tcttctgtca agaaatactt gcgactaata tattcaacca tcccctcttc aaaccagatg
      601 taagagtcgt aaccatcaaa atcatctaaa aaatactccg accaatgagc taactcatgt
      661 cctacaatct gtaagaggaa attttcagat aaagaatgat aatggctttc tattgcttga
      721 gtttgctgag aacactcgta gtccatcaac tgatacaaat acaactcttt ccatacagct
      781 aaatcaggcg tcataaccat tcgtctatta tttgtatagg ctggaacagc gctttcccta
      841 ataatctgtg tagcagcatt aaaacttgac caaataacgg cttgcggtaa atcacagact
      901 gcaagttcat tctttaaaaa agattgataa tctttcaact tttcagtatt tcttactaca
      961 aaatcacgaa atgcagctag ttgactatcg tcttttacaa gataaaggtt gtccacggct
     1021 ctcctttctt tcacacaata gactaaataa gcaaaagaac cgcgtccgac aatcctaggt
     1081 tgatttaacc taggggcgtc agaaacgcgg ttccacccta atttattact tcattgtttt
     1141 tgaaaatact acagaaagcg ccagcccttt attttgccct acttggctcc cactatccca
     1201 agctcgcttg aagaacgcca taagactttc tttcctgctg actattatat caaaaattag
     1261 aataatgtac aattcttttt atgattttct agaaatccac atcatcaact cgtggagcac
     1321 ccgattgaac agcaatcgtt tttaaggttt ctctctcctc atgactcagt tcaattccaa
     1381 agcaatcaag attagcttga atacgagagg ttgtgacaga ttttggaagt ggtaaaaatc
     1441 cttctgccaa gctccaggcc aaggctatct gagcaatcga ttttccgtga tttgctgcga
     1501 tttcttgcac ttgcttgcta tcaaatagtt ctccctgacc aaaaggcccc caagcttcca
     1561 ataaaattcc cttttcacga cagtaagcta cgacttgatc ttgatacaca cctggcgcca
     1621 agcgaacttg attgaccgca ggaacgatag ttgcagtttc aagcaaggca tccaaatgat
     1681 ggggaagaaa attgctaacg ccgatagcac ggattttccc ttcttgatag aggtcttcca
     1741 tcgctctcca aacttccgca ttgcgagttt tccatgcgtc attttctctg agcggttttg
     1801 ggttcggcca atgaatcaaa tacaaatcca aataatccaa gcccagtttt tctatagatt
     1861 tttccaaagc ttgacgagtt tgctcatagg tttgctgact attccaaagc ttggtagtta
     1921 cgaacatttc ttcacgtgga actccgctat ctttgattgc ttgaccaaca ctttcttcat
     1981 tctgataaat cgccgccgta tcaatatgac gataaccagc cttcaaggct tctaacactg
     2041 cacgataggc ttcttctcca tccttagcct taaaagttcc aaatcccaat actggaattt
     2101 ctactccatt atttaattga taggtattca tatgcttctc cttctatttt attcatcaat
     2161 tatagcataa aacatttttt aagtagtact atcttctgta aaaaataagt ctgtcaaata
     2221 tctaacagac ctattttttc ttgcttattc atcacgacta tagtacagct catgagcttt
     2281 taggcgagta ttgagcatct ctggtatggt cacaaaggta taaccttgat ttttcaaata
     2341 ctcaatgacc cttggcaagg cattgactgt cggactgtga atatcatgca tcaaaacgat
     2401 agagccgtta gctacttgat gctgaatttc tgtcaaaata gatgcttcat ttttactctt
     2461 ccagtccaga ctatccacat cccacatgat aaagctcaaa tccaagctat tgcgaatatc
     2521 atctgtaata gcaccataag gtggacgcat gagtttagaa ctagaaccca gcactttagt
     2581 tagcacatcc tcagtatcag taatctgctt tttagcttca tcaagagaga gttgcgagag
     2641 aatcggatgg ctccaactat ggtttccaac aacatgacct tcagatttta tcctcttcac
     2701 caagtcctca ttcccagaaa catttttccc aagcacaaag aaagtcgctt taatatcata
     2761 tttagctagg gtctctaata cctgcggggt cgttgctgga tttggaccat catcaaaggt
     2821 tagagcgaca actttttgat atttcttatc aaagtaagat tggtacaagg ccgcatcttt
     2881 ttcgagtaag tacgaagatt ggataacatc aaagaaagca gatactggca aggctatctc
     2941 ttctaaattt tcaaccacag gacttggata aaggataatc tgactatcct tgtaatcaaa
     3001 attccatgca gacaagtctt ggtcagagaa gttttttaca atctgctcac tctggtcttg
     3061 ctctattttt ttatcctcta tgaaggaggt caactctttt atcagctgtt ccttagcctt
     3121 actagcatct gaaaacagtt ggtcaagtgt aaaaggttgc ccatcttctg ttaagtgaac
     3181 ctttcctaga ctggtctttt cagtctcttc aaccttaaaa gcaactaaat catagatttg
     3241 tttggtcaca ttacgattaa cgactccctt taaacctgac tcttcttgct ctgtatagta
     3301 gaaaacaaga ttgtccttac tttctagctt gtccttaaca tcttgattta tcaactccct
     3361 aacagaggaa atcactttct ccccttggag aggataatag gcaatcactt cggcttgccc
     3421 ctgacgaaaa tgctccttct gatttccctc actcaattga tcatctttct cttttttgag
     3481 cgattcaatc ttttgctcaa aacttttttg ctggtagatc ttaaaagcaa taaatccgcc
     3541 taataggcaa atagaaattg ctaaaatacc aatcaaagcc aataatacat gtctcgtttt
     3601 cccgtgtctg ccacgtccta gtctactttt attcatattt atatcataac aaatttgagc
     3661 aataatttca atgatacaat ttggcaatcc acaattcctc tagcaagcca aagcatctta
     3721 catcaactcc aacatccgta tctgtagaga ttatgtagtt ttctatctat ggaatttcta
     3781 gtagattgaa gctagaatag tagacctata cttctaaaac attgttagaa atcgatttga
     3841 ttgtcctgat cgatttgtcc tgttcttatt tcattttact ataaaactat gagaagctag
     3901 gtcatctgag aagtaattac tatcgacaat tgcgatagcg tatactggtg caatttgttt
     3961 gtagctctgg tgggtatcac cttcacgttg gcgaattttt tctaggtttt gattaacctg
     4021 actgcacaga taagcccata ggcgattgat gaaaaaattc tgatgatgaa cctgaatttc
     4081 gatgataact tgggttccat tatctaactc cgccaagaca tctatactag tatagaaatc
     4141 ctgcgctgag tagggcatgg aaggcaagac gtgaatgtta cttccctcca aaatcgtcac
     4201 attttttgct ggcaagtcca gcatatcgcg gataaattga caaagcatta gttgggttga
     4261 tacccggatg tctgagaatc ctccttttcc tcctttttct cctctctgtt ggatagtccc
     4321 gtctatctat gttataataa aagaaggatt taaaatcgga aaaggagtat ttatgctaaa
     4381 attaggtgtc atcggaactg gcgctatcag ccatcatttc atagaagcag cccataccag
     4441 tggagaatac caactggtcg caatctattc tagaaaacta gaaactgcag caacctttgc
     4501 ttctcgctat cagaatatcc aactattcga tcaattagaa gtcttcttca aatcttcttt
     4561 tgatttagtc tatatcgcca gtccaaactc cttacatttt gctcaggcaa aagctgcctt
     4621 gtctgctggt aaacatgtta ttctcgaaaa gccagctgtc actcaaccac aagaatggtt
     4681 tgatttgatt caaacagctg aaaaaaataa ctgttttatc tttgaagcag ctcgtaatta
     4741 ccacgagaaa gcctttacta ctatcaaaaa ctttttagca gataagcaag tgttaggagc
     4801 agatttcaac tatgccaaat actcttccaa gatgcctgac ttgttgactg gacaaacacc
     4861 aaatgtcttt tcagaccgtt ttgctggtgg agccctcatg gatttgggga tttatcccct
     4921 ctatgctgct gttcgtcttt ttgaaaaagc taatgacgcg acttaccatg ctcaacagct
     4981 tgacaatagc attgacctaa atggagatgg tatcctcttc tacccagact atcaagttca
     5041 catcaaggct ggaaaaaaca tcacttccaa tcttccttgc gagatttata caacagatgg
     5101 aaccttgact ctcaacacga ttgagcatat tcgctcagct atttttaccg accaccaagg
     5161 aaatcaagtc cagcttccta tccaacaggc tcctcatacg atgactgagg aagtcgctgc
     5221 atttgcacac atgatccagc aaccagatct gaatctctac caaacttggc tgtatgatgc
     5281 aggctctgtt catgagctac tatataccat gcgccagact gctggcatta gatttgaggc
     5341 agaaaaatga aaaccaaact accgactgaa tggcaagaac tgagtgacca actcggtttc
     5401 caagaattca cccccattca aactcaacta tttgagcccc ttcttgctgg agaaaacctc
     5461 ctaggagtga gccaaaccgg aactggtaag accctagcgt atctcctacc aagtcttctc
     5521 agactacaaa agaaaaaagc ccaacaactc ttgattctag caccaaatac ggaacttgct
     5581 ggacagattt ttgatgtatg taaaacgtgg gcagaagcta tcggattgac tgctcaactc
     5641 ttcctttcag gttcaagtca gaaacgacaa attgaacgtc ttaaaaaggg gccagaaatt
     5701 ctgattggaa ctcctggccg tatctttgaa ctcattaaac ttaaaaaaat caagatgatg
     5761 aatgtggaaa ccatcatcct ggatgaattt gaccaattac tagatgattc tcagattcac
     5821 tttgtagaaa aaatcactca ctacgcacct cgtgaccacc aactggtcta catgagtgcc
     5881 acgaccaagt ttgaccaaga aaagattgtg ccgaatacac gcactattga tctctctgat
     5941 caaaaattgg acaatatcca gcatttctac atgcaggtag accaacgtca tcgagtggat
     6001 atgctacgaa aactggctca tgtagaggat ttccgtggtc tagtcttctt caatagcctg
     6061 tcagaccttg ggaatgccga ggaaaaacta cagtatcgtg atatattggc tgtttccctc
     6121 gctagtgatg ttaatgttaa atttagaaaa atcatcttag aaaagtttaa agataaccaa
     6181 ctaaccctgc ttcttgcaac tgaccttttg gctcgtggaa ttgatatcga tagcctagaa
     6241 tgtgtcgtaa actttgatat tcctagagat agcgaaacct acacacaccg tgctggccgt
     6301 actggtcgta tgggcaagga aggttatgtt atcactctcg tcactcatcc agaagaaatc
     6361 aaaaaactta aaaagtttgc aagtatccga gaaattgtcc taaaaaacca agaactctat
     6421 atcaaataaa gccccattgc tctatacaca tccagtgtat ggagcttttt tataagcaat
     6481 tcaattttat actcatctgc tttcaaaaag cattctattc catctccgat taacgatgga
     6541 ctttatcacc tccttctcca atccttgtat gacatcttgg agttgattca tgacatcttc
     6601 caaagttcga aaggctttat tcttaaatcc acgtttacga atctctttcc acacttgttc
     6661 aatggggttc atctctggtg tgtatggagg aataaaggta aaatcaatat tagtcggaat
     6721 atttaaggta cttgatttat gccatatagc attgtccata acgagtaaaa ggataagctt
     6781 gtgaaagctc ttctaaaaag gcgttcatcc actcagtatt acatccacca gctattaaga
     6841 aaaatgattc gcctgtatgg ggcatcaaca gctccataac aatagcgaaa ttctcgtata
     6901 tagtgactat ggacatgtgg acctactcct attggagacc aacaagatcc cagtttactg
     6961 attctaccga aaccagcctc atcttggtac atcaagcgaa ccttatgaaa acgtctacta
     7021 tatttaaaac gctttcttgc cttcttggat tgagatttta tttttagacg cgacaatggt
     7081 ttgagcgtct gctttcttag gatgttctgg acgtggcata atattcgcca accatggcgc
     7141 ttcaacagtt gatagaaggc atcacgtgtg taggaacgat ataagcctga aataaggtat
     7201 tgtaacaaat tctcctgcct ctgtagcctt caaatggcgg gcaagaaagg ctttctcttc
     7261 ctaaactgtc atatatgcat ggttacgacc accacgtgtt tcttgaagga gagagtcgag
     7321 tccgaactcc tcatattttt ttacatttcg ccaaatcgtt gtttgattac agtctaaaag
     7381 ctctataatc tctctttata agatttgccc atcagacgaa atagaacgat ttgaaggcgt
     7441 ttatgatatt tagctgtacg agagtctttt aaaagtgttt tgatggtttg gatttcttct
     7501 ttagttgatt tcatattact attgtataat gctttttgat tttagtctag tattatactc
     7561 ttcgaaaatc tcttcaaacc gcgtcagctt cgccttgtcg tatagatgtt actgacttcg
     7621 tcagttctat ctacaaccta aaaacagtgt tttgagcagt ctgcagctaa ctttctataa
     7681 caaaatgaaa taagaacaag acaaatcaat caagacaatc aaatcgattt ctaacaatgt
     7741 tttagaagta gatgtgtact attctagttt caatatatta tagtttgctc tttgattttc
     7801 attgagtatt agttcaatat ctaaaaaaag aaccttgcca agcaagattc ttttagtgtc
     7861 tgacttaaat aattgttctt ctgggaacta aatcgaatta agcttcgatt tctgtaacca
     7921 tacctgaacc aacagtacgt ccaccctcac ggatagagaa tgtagtacct tgttctacgg
     7981 cgattgggtg aatcaactca acgtcgattg tcacgttatc accaggcatt accatttcag
     8041 tacctgctgg aagttcgatt gaacctgtaa cgtcagtagt acggaagtag aattgtggac
     8101 ggtagttgtt gaagaatgga gtgtgacgtc caccttcttc tttagtaagg atgtagactt
     8161 cacctttgaa tttagtgtgt gggttgattg aacctggttt agcgataact tgtccacgtt
     8221 cgatttcatc acgttgaaca ccacgaagaa ggacacctac gttatctcca gcaagacctt
     8281 cgtcaagttg tttacggaac atttcaacac cagtaacaac tgctttttga gtttcttctt
     8341 tgataccaac gatttcgatt tcgtcgttga ctttaacgat accacggtcg atacgtcctg
     8401 aagcaactgt accacgtcca gtgattgaga atacgtcctc gactggaaga agcaatggtt
     8461 tgtcagtgtc acgttctggt tctgggatat actcatcaac tgtgttcatc aattccataa
     8521 cgatgtcttc gtatttagag tcaccttcaa gagctttaag tgctgaacct tggataactg
     8581 gaagatcgtc acctgggaag tcgtattctg acaataggtc acggatttcc atttcaacca
     8641 attcaagcaa ttcttcgtcg tcaaccaagt caactttgtt catgaagacg ataaggtgtt
     8701 taacaccaac ctgacgtgaa agaaggatgt gctcacgagt ttgtggcatt ggtccgtcag
     8761 ttgaagctac tacaaggata gctccgtcca tttgagcagc accagtgatc atgtttttaa
     8821 cgtagtccgc gtgtcctgga gcgtcgatgt gagcgtagtg acgtttttca gtttcgtact
     8881 caacgtgcgc agtgttaata gtgataccgc gttcgcgttc ttctggagca gcatcgatag
     8941 acgcatagtc tttaggttgg ttaactgatg aaggcaagcg acgtgccaaa acagttgtga
     9001 tagctgcagt tagggtagtt ttaccgtggt caacgtgtcc gatagtacca atgttaacgt
     9061 gtggtttact acgatcgtat ttttcttttg ccatttgagt aaaagcctcc aataaaatat
     9121 attttataga tagacagtag gcaatacagt ctaactttcc ttactatttt atcaaatttc
     9181 agctaaattg caagtgtttt acaacgtttt tgtgaattat tcttggtaaa aatttaacta
     9241 actaatagaa agtactaaat agacttatcc ttcaaggagt tttcagcatt atccatccac
     9301 tcacttgctg aaaatgtaaa cagtctctgg tttatatagt aaaatgaaac aagaataggg
     9361 caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagttg aggtgtacta
     9421 ttctagtttc aatctactat acaacctcaa aactgtgttt tgaacaacct gcggctagct
     9481 tcttagtttg ccctttgatt ttcattgagt ataaaattgc agataaaacg ataacaatca
     9541 taggactcag cagagtcaat gtaggtcgaa gaatagcccc cctaatcgct tattttatag
     9601 caaaatgaaa tagaaactga acattttgtt gaggaaggta aatcaattcc tcacaatgtt
     9661 tgagaaagaa gggaggacta ttccaacttc aacccactat aaagcagact tacaagatag
     9721 ggaacccatc tccgataata ttccgataat atatagtaga atgaaaactg cacaatttga
     9781 ttggagaatt caaaccaatt tctaacaatg ttttagaaac aagggtctat tatttcaact
     9841 gcaacctact atagcccatt gaagctggaa tagcccactg agacttctaa accactgctg
     9901 gagaggagtt tgtttagagt ttgtttagag tttctttcat ttccctaaaa aatcaaaaag
     9961 agagaaccag tctgatcctc tcttacttat agatggtgct cactcaaatg ttaaaggagc
    10021 tatttcttag agataaagga atttgaatac agctactgcc gcaattgctg ctgcgatagg
    10081 tgctactact ggtacccaag aataccacca ttttgaatcg cctttatgct caccaagaac
    10141 tgattttgga aggaaagcat gaaggagacg tggtcccaag tcacgggctg ggttcaaggc
    10201 aggtcctgta ggtcctccaa gtgatgttac caaagccata acgaggaatc caagtgccaa
    10261 gtgagccaca gaaagtcctg aagcagtgtg tggagccacc tgtgctttaa tagccaagtc
    10321 agaaaaatca actgtttgtc ctgcttctat tgccttttgt ttcatgaatt gaagcacttc
    10381 agcaccaaag aagtttttag tcaaaccaag agctgcaaag aacaaaacaa atgaaccaac
    10441 aaactcatta atcaaaccat tgacagttgc tgcatagcga ctttcttttg taccatggtc
    10501 aatacttgaa atagttgaga aagttcctaa gatgttattt ggtttttcag ttttcaagta
    10561 gaatggacgg tatgttgcca caactaaggc ttggccaaag atagccccca agacttgcgc
    10621 gataatgtaa ggtaccactt gtgcccaagg gaaaagaccg ctaactgcaa gccctagagt
    10681 gaaagcaggg ttgatgtgat tcccagatac gttaccaaac atcaaggctg ggatcataac
    10741 ccccatacca taaccaacag cgatgacgat ccagccactt tggtgacctt tcgtaccttt
    10801 aagttcaacg ttggcaactg caccattccc aagaatgatc aaaatggcag ttcccaaaaa
    10861 ttcagtggca tacttcagtg cccatgtgaa atccatttgc tagattctcc ttaaaatttt
    10921 ttagatattc cttattttat caatttttac cctatttagc aactgatttc tggaaatatt
    10981 tttaaaaaaa taggattcat agtttcccag ttcaacgtac ttgtaagcgt ttttatcctt
    11041 cacaaaagac ctcattctca aaaccaggaa aaagcccaca tctgtgatct tttccttgtt
    11101 cctagattct aaaatctatt atttttcatc ttcttttttc ttgaagaatc ctaatcctag
    11161 accagctaac aaggtcatga taccagcact agccaaggta gcattagctt ctgtacctgt
    11221 gtttggcaat tcctctctct tacctgtctc ataagtcgga acttctgggt ctggattcac
    11281 tggagtttca gtttttggag tacctggttc tggagttggt ttatctggtg ttgataaacg
    11341 gtcatacctt accgttattt ctttatcact agagtctgac gtaacttctt gtgattcaac
    11401 tgttggaata tctggatctt tgtacttgtc aatcttacca gatataacct cgtcccagtt
    11461 tcctgttgtc cattcaccgt aggttacaac tcccgtgacc ttgtctcagt ttttgtacgg
    11521 cttaaggtta caggttgaac aacatcttct tttacatttt ggttcgtaac tttatcaacg
    11581 taatgaatga tacgcgttat agtcttcgtc tcagtagagg ttgctgtttt gggaaccact
    11641 gtttcctcaa cattctcacg gtagtaatag tcaactgttg caccgtcttc tggtacgcat
    11701 ttgcaggagt tgctaccaag gtgtatgttg ttttccttgt gataactcgg tcttctttgt
    11761 cctcagttgt tgttttccct tcaatagttt ttgattctgt ggtatactca gaacctatcg
    11821 ctaaatcagc ttttataaca gactctgcca acttctcttg gctaccttct ttatagtaat
    11881 tggctgttac tgtagcagtg gttggcgctt cgctttctct ataaactaag gtcactgttc
    11941 taccttcgct tacaatattc ccagttaaac ttgcagaatt tgtatctgct tctttaaaag
    12001 tataatattt tccgtcagta gtagtcatgc tactgagttt tttatctgtg acattgtagc
    12061 tggtaccaat cagttgtttt ttattggtaa tgtaggttcc gtcactttct ttttctccaa
    12121 ttccagtatc atttttcaat gatagcaaac gcccttgttc atcaacatag cgaactttca
    12181 cattttctga gattagttct gccaattctg aggttttttt ctttttcttg atttcttcgg
    12241 ttattttccc tttctcttct tcgggaatat ttagttttgg aatgattttt tcaacaacgg
    12301 ttcgtgatgg ttccacagta tcttggatga ctgaaaagtc agctagaatt gggagattat
    12361 actgaacacg gtaactttga gtgtttactc ctactctttc attattctct gaaaatactt
    12421 gtacggtata agaaacaaca tcttttccta atagaacatc cccagtagag aaatagccgc
    12481 cttttcctag tttgctatct ccagagccca cttctttcct aatcttatca gatagttttt
    12541 taccagtcag tacattcgtt cgcacaatcc ctttgtctac ccctacaaag tgggagaact
    12601 ttttgaactc ttcagaacca gatctagccc aaccattatt aagggcattt gcttttgtat
    12661 ttgtattctc tctcaaaagt ttggcgatta gaattatatt catcggcact tagagttgct
    12721 gctatatctg actcttgaat accaacttcc ttactaccat ttctagcggc agtatatgtg
    12781 tatttatctg tttctacttc tagctgatta tccttaacat gataggtaat tttctcctgg
    12841 tataagagtc ttcagtagtt tatatgctct gtcatcatct ttagctttag aagcagctga
    12901 gtttagccaa gttggggtat taggagtatc tttatcagcc tgtttcaaga cattattcaa
    12961 gtcatttgct agcctattgg ttgtcctcac tgtgaaagtt ttcttccagt ctgaaccact
    13021 tttattagac ttagatatgc tcatgaaatc ctggtcaaca ttcaacacaa tatcgccttg
    13081 ttttttagca tcttccgttg cttctgcttc aaattgatca tggagttttt gttgctctgg
    13141 tgtatagttt ttttatttac acgatttaat gtactatttt ttattttagt attaagaact
    13201 ccattaatac gatttttaaa ctctgcttca aaaaatccct taatttgttg gtgcgcaagt
    13261 tcaacattca aacctttctt atacaagtct tcattctgat acaagtcttc attctgaacg
    13321 atttcggcta cacggtgaat ggtttgattg tataccgtct tctcttaacc agcagtatcc
    13381 ttagttttaa tgactactcg ataggttcct ttagaaccgt tatagtcatc tagttttaaa
    13441 aaagcattcc aaacattcaa aaatagttgg aacttccctt aataaatccg tcactttctt
    13501 tttcaagata gcccaagctt gctcaatagg attcaaatcc ggtgaataag gtggtagagg
    13561 taagaaaaag tgtttatctt ggatgcagag ttcatccaaa atgttcttgg gatgaaaact
    13621 agcattgccc atgacaataa catgaggtgt cttcaaagca ggtaggagtt gcgttttgaa
    13681 ccactccaca aagaaatcgc ttgtcatgct tttcttgtaa atcatgggag ctataaactc
    13741 tccgtctact tgtcctgcaa caattgaagt tcgctcaaaa cgacgtccgc taatcttttc
    13801 atagactttc tcccctctag gagcccctgc ataaggacga tagaggtagc ggtcgattcc
    13861 tgtttcgtca atatatacga ttggtaaatc ttttaggtta tccaaaatat caagaaactc
    13921 agcgactttc tctggctctt gttccttaaa gctcgtcatc tttttttaaa gtgaccttaa
    13981 tctgctttaa agctgcccat actgaaggaa cagcacaatc aaaatgtgcc gcaatttccc
    14041 gtaaaaaagc atctggatga gcctctacaa aggttttcaa ttcctctaaa ggaatctttc
    14101 ggtttttgac gactcgcttt ttcctctcta tgtgttcttg ttcacgtctt tcttttccca
    14161 cgtgaagaga gttctgacgc caacaccaaa aaactttggc cgcctcgaca tgtctgtgcc
    14221 ctcctttgat ggaatctaat gctccttgtt taaaatcagt attatatgcc atagctttat
    14281 tagaccatgc ttattttaaa ctaagcaact atatcaatgt tttgttatga gaagacttac
    14341 tttttttact gaaattgaat ttttcctagc ctcaacatca tataacccca aaattcaatc
    14401 tgacctggtt tgaagagatg ttcgaagcag ataaggtttt actaaaacta aaaaaaatga
    14461 tataatcaaa ttgattaaat gttttaaaaa taaaggagaa tttgaatgtc ttaccaagaa
    14521 aattaccaga aatgggttga ttttgtggag cttcctgact accttcgtca agatttggaa
    14581 aatatggacg aaaaaactaa ggaagatgcc ttctatacaa atcttgaatt tggtactgca
    14641 ggtatgcgtg gcttggttgg tgctggtaca aaccgtatca acatctacgt tgttcgccaa
    14701 gctactgaag gattggctcg tttgattgag tcaaaaggtg gaaacgagaa agaacgcggt
    14761 gtagcaattg cctacgatag ccgtcacttc tcacctgagt ttgcctttga atctgcggca
    14821 gttcttgcta aacacggcat caaatcttac gtatttgaaa gccttcgtcc gactccagaa
    14881 ctatcatttg cagttcgtca tctcaactgt ttcgcaggta tcatggtcac agccagccac
    14941 aaccctgctc catttaacgg ttacaaggtt tacggtgaag acggtggaca aatgcctcca
    15001 cacgatgcgg acgctttgac tacttatatc cgtgcaatcg aaaacccatt tgcagttgaa
    15061 gttgctgatg tggaaactga aaaagcttct ggcttgattg aagttatcgg cgaagctgtt
    15121 gacgtagaat accttaaaga ggttaaggac gtaaacatca acccagcctt gattgaagaa
    15181 tttggtaaag acatgaagat tgtctacaca ccacttcatg gtactggtga aatgttggct
    15241 cgtcgtgctc ttgcccaagc aggatttgac tctgttcaag ttgttgaagc gcaagcaact
    15301 gctgacccag acttctcaac tgtaacatct ccaaacccag aaagccaagc agcctttgcc
    15361 cttgctgaag aacttggtcg tcaagttggt gcagatgttc ttgtcgcaac tgacccagac
    15421 gctgaccgtg ttggtgttga agttcttcaa aaagatggta gctacctcaa cctttcaggt
    15481 aaccaaatcg gtgctatcat ggctaaatac atcttggaag ctcacaaaaa cgctggaact
    15541 cttcctgaaa atgccgctct ctgcaaatct atcgtttcaa ctgacttggt aacgaagatt
    15601 gctgaaagct acggcgcaac tatgttcaac gtcttgacag gtttcaaatt tatcgctgaa
    15661 aaaatccaag aattcgaaga aaaacacaac cacacttaca tgatgggatt tgaagaaagc
    15721 ttcggttact tgattaaacc atttgtacgt gataaagatg ccatccaagc cgttcttgtc
    15781 gttgctgaac ttgctgccta ctaccgttct cgtggtttga cacttgctga cggtatcgaa
    15841 gaaatctata aagaatatgg ctactacgca gaaaaaacaa tctctgttac tctttcaggt
    15901 gtcgatggtg ctgaacaaat caaagcgatt atggctaaat tccgcaacaa tgctccaaca
    15961 gaatggaacg caacagctat cactgtcgta gaagacttca aggcacaaac tgctactgtt
    16021 gctgacggta ctgttacaaa cttgacaact cctccaagtg atgtgttgaa atacacactt
    16081 gctgacggtt catggattgc cgttcgccct tcaggtacag aaccaaaaat caagttctac
    16141 attgcagttg taggggaaac caacgaagaa tcacaagcta agattgctaa catcgaagca
    16201 gaaatcaatg catttgtaaa ataaagacct ataaaagatg agaccaacca acctcatctt
    16261 ttttcgtatc aaatctaagc aattttagaa actttatggc atactagact tatcaatgaa
    16321 agcgaggtaa tctcatggaa caatttttag ataacatcaa agaccttgaa gtcactacag
    16381 ttgtgcgtgc gcaagaagct cttgataaaa aagaaactgc aaccttcttt atcggtcgca
    16441 aaacttgccc ttactgccgt aaattttcag gtacattgtc aggtgtcgta gctgaaacca
    16501 aagctcacat ttacttcatc aatagtgaag aaccaagcca actcaatgat ttgcaagcat
    16561 tccgctcacg ctatggaatc ccaactgtac caggttttgt tcatattaca gatggacaaa
    16621 tcaacgtccg ttgcgactct tcaatgtcag cacaagaaat caaagatttc gcaggattgt
    16681 aaaaaatcag ctaacaagtc ttaaaatcac aaaaacgcat aatgtaaggt gcaaaaacct
    16741 tgatattatg cgttttattg ttcctaaaac agttacatca gcatttcatt acagaacatt
    16801 ttaattttgg aagtcaaatc aatttttaac aatgttttag aaatcacagt gggctattcc
    16861 atattcaatt atccagattc aatcgctatt atcgttttcc tagattacaa aaaaaactac
    16921 gttttgctaa tcaaaacgta gtctcagcca ctattttatc ttactgtcct tcttttactt
    16981 ctttggttgc tacatcttct ccaaaccatt tttggctgat ttcttggaac ttgccgtcct
    17041 tgtaaagact agaaaaagct tcatttatct tcttaaccaa ggttgtatct tccttacggg
    17101 ctccaaccgc aaaagcttct gtttctagtc caactgtaaa gacattataa tcgtttaaaa
    17161 caccttctgc ttctaaataa tagtttgcat agacacggtc aatcaataga ccatcaattc
    17221 gatcgttttt caaatcaatc aaggcttcat taaaggtttg gtattgattc gcttccttat
    17281 tagcgacaat attcttcaaa agttctggat ttgcttcaaa gtccgcataa ccagatgaac
    17341 cagcttgagc tcctaatgtc tttccagtca tatcctttgc agtcgtgata ccagatgatt
    17401 tcttcgtaac caatacctgc tcattcttca tatatgagtt actgaaagcc accttttcac
    17461 ggcgttcgtc tgtagcggaa tagccattcc aaatcagatc aatcgttcct tttgtcaatt
    17521 cagcttcttt caaatcccaa tcaatcggtt gccaatttac cgtgattccg tatttttcaa
    17581 aaacagctgt agctaaatca atatcaaatc ctgcataaga accatctttc tgagcaaatc
    17641 ccattggaac aaaagtacta tcaaatccaa tagtaataga cttgttagac tggtactttg
    17701 accaattatc tccactagtt tcgctagaat ttttcccaca agctactaag aacaaagcag
    17761 tcatcagact gactaataca agcatccatt ttttcatcca tttttcctcc tatttaggtt
    17821 ctactttcaa taatacatct gcgatatttt cagcaaactg caaatcatgg gtaaccacaa
    17881 tctgggtcat cccaagttcc ctattttgca agattagctt ctccacttcc aaacgtaatt
    17941 ctggatccag ggcagaagtt ggttcatcgt agccaatgat ttctgggtca atcatcatag
    18001 cacgcgccaa agccactcgc tgcttttgcc caccagatag tgagaaagga taggcctctg
    18061 cgtgtcctcc tagtcctaac tgttccaaga gtccactcgc cttcttctca gcctcttcct
    18121 gcttcattcc catggtcttc acaggcgata aagtcaaatt ttccagaact gatagatgag
    18181 gaaatagttg aaaatcttgg aagacaaatc ccagtaggtt gcgcttctgc aattcatcca
    18241 gctctaaagg ttgtccatta taaaagattt gccctgaatc aatggtttca agacctgcaa
    18301 gcatacgtaa aagagttgtc ttacctccac cagaaggtcc aacgatagcc aggatttgct
    18361 tttcaggaat acttagactg aaattagaca ggatttgttt gtctccaaag actttattga
    18421 tatttcgtaa ttctaacatg gcagcctcct atctataata actatacttc ttctcaactt
    18481 ttttggaaat aattgtcaca atcccaatca aaatcaaata aatggctcct gccaagaaca
    18541 taggaactag actagcatcg cggttagcag ctgttcgact agccaagata aggtctgaaa
    18601 ttccgagagc atagaccaaa gaagtatcct tgaccaaact cataacttca ttaaagacac
    18661 taggaagaac aatcttggtc acttggggca agataatata gcgcactctg tcaaaagggc
    18721 taaactttaa gaccttggca gcctcatact gtcctcttgg aatagtgtca attcccccac
    18781 ggaaaatttc tgcaaagtaa gctgcatagt tgagaacaaa ggcaataata gctgcaggaa
    18841 ggcggtctaa acgaatccca atacttggga gcacataata gataaaaatc agttgcaaga
    18901 gtaagggggt tcctcgcata acccagatgt aaatgttaat cagataatgg aggggcttcc
    18961 aatggacttg caaggcaaag gcaatcaaaa cgcccaaggg aatcgaaaat agcaagacca
    19021 gtgcaaagac ctgtacagtc gtgctcgcac cattcagtaa actcggtaat atctcaaata
    19081 aataagacat actgcacctc ctaaaagtaa ttgttcctat tatagcatga ataaacaaga
    19141 ttaccaagta tttttgtaaa aagattctac catatacaaa taaaaaccgt agctatcaaa
    19201 agagataaac tacagttcta tatgtttaaa cattcttaca atctctcaaa cagttcttgc
    19261 atttgcacat catctggaac cagttttaag taagtgtgag catggacttt tgcttcttca
    19321 aaatgtccca attcacgcaa gagatagata tagtgttcca gaaattctgg attgtccttc
    19381 aaatctcctg tcaactcttg ataatgctca taagcagtat ccaaatcgtc catttcttga
    19441 taagaacgag caatcatcca cttggtcaaa agattttctg gctcctcact ctgcaagtct
    19501 agaatatcct cataacgctc ctgctccaga taaatagtgg ctaaacgaag caagatttct
    19561 tctgtatcct cagcgtcttc ttttgcagta aggagataat tttctgcacc actagcatca
    19621 tgcaattcat aagaaaattg tgaagcagct agcaagaggc gagtttcaaa gggatttttc
    19681 tctaatcctt gcttagcgat acgcagggct tcttgaactt gatgttcctt atgtaaagcc
    19741 tgactgtacc catactcata gccttcaaag tcaggagaaa tggtatcaag ctgcttaaag
    19801 tagagggtgg ctttttgata ttcttcttga tcaaaataaa gactggccaa ctcaaaagct
    19861 gttaagtcat cgtattctaa ctccagggct ttttctaaaa actcagtagc cgtttcaaat
    19921 ttccctaact gagcataggc aaagccaatt cgttgatagg tggaaatgcc cgtttgctca
    19981 taaatcgagc gattatctaa ctgggcatag gcttgaatag ccgcttggta attttccaac
    20041 tcactatcca actctgccaa acccaatatc aagagagaat cctctgagta ggtcaaggcc
    20101 tccaataatt tctcacgtgc cacatctgtc aaaccttcca gctggtaaag gtctgccttc
    20161 aaaaccaaag acgagacata ccagtcactg tcagcttgga tttcctcaag ataggtaaag
    20221 gcttcttcta tttgaccatc ctcgctagca attgcagcta gattaagatg aacctctgga
    20281 aaatcctcta caattttcag gtaaatttcc ttggcctgag gatagaaacc aatcccttca
    20341 agataagttg ccaactcata cagaagatta cttgaatcat tttctaaagc tttggcgaaa
    20401 taatgctcag ccttagttaa atcttgctcc tccaaagcct gtaacatctg ttgactattg
    20461 ttcactcttg acttcctcac cctctaattc atatagacca ctgactacct tataccattc
    20521 gaaaatggct gaaatgacaa ccttagcaga ggcataaacc ggaataccaa gtaaaactcc
    20581 ccagatacca aacatagatc ctgaagttaa caaaacaaag agaacattaa tagggtggat
    20641 gtttaattga cttcccaaaa tcaatggaga gacaaaacgg ccttcaatag tttgttctac
    20701 gataaagaca atcactactt tcaaaagcat gactggacca gcaatcaaac ccaatactag
    20761 agcaggaagc atggctagaa agctaccaag ataagggacc agatttaaaa taccagcagt
    20821 aacccccagc gtaaccgcat agcgtagacc aataatcttg aagaagatga taaacattac
    20881 tgctacaata atagccactg tcacttgccc tcgaacatag ttggacaact gttgattcac
    20941 atctgataga acttgtccaa caggttcctt caattttctt ggaatgaatt gggtcaaata
    21001 gttacgcaag cctttcccat cacgcaagag ataaaagagc atgaaaggaa cgataatcaa
    21061 ggcaacaatc acttgagaag ctccgctaat aaaggcactc acccagttga ctgcctgaga
    21121 tgaaacctta cttgccaaaa ctgtagcctg gctagaaaaa ttggtcaaaa cttgctctaa
    21181 ttgaggtctg aaatcatctg gcaggtgctg ggctaccaat ccattaacaa tcctatctat
    21241 atcttctaag taaacaggaa cgtttcttgc aaaggtcaaa acctgacgtt gcagatttgg
    21301 aatggcgact gccaagcccc aaatgataaa gagagcgatg ataacaaaga caatagtgat
    21361 agctataaca cgattaacct tatgcttctc catccaatca acaataggat tcaacaaata
    21421 atataacaaa ccagacaaaa tgactggcaa catcacaact gctaaaaagt ctaaaacagg
    21481 tgaaaataga aaactaatct tacttaaaat aaaaagattc agtcccaata ataaggttac
    21541 taaaaatacc gtaattgcct tgttatctaa aaaccacttg aaaaaccaag ataggctaaa
    21601 atgtttctct ttttgctcca taaatacttc ctttctattg tcctctcatt ataccatttt
    21661 tgaaacaaaa taactctttt ttaaagtgct tacatctaat tggatatctt taatttactt
    21721 gtttttgtga tataatagtc ttatctttac acagaggtat agtaatgaaa gaaactgttt
    21781 attttggaac ttatacacgt cgtacttctc aagggattta caaggcagac tttgatacag
    21841 aaactggtca gctttcaaat ctagaacttt ttgcagctga gccaagtcca acctaccttg
    21901 cctttgacca gcaccaacat ttatacactg ttggtagcca agacgataag gggggaattg
    21961 cagcctatca aactgacggg actgtgttaa atcatgttgt tgaagaagga gctccccact
    22021 gttatgttgc tgtcgatgaa aagcgtgatt tggtttacgc agccaactat cacaagggac
    22081 aagtccttgt ttataaacgc caggaagatg gtagtcttct acttagtgat atggatcaac
    22141 acagtggcca aggtccacat gaaaatcaag cttcccccca tgttcactat acagatttaa
    22201 cacctgacca ctatctagtg acctgcgact tgggaactga ccaagtcatc acctatgacc
    22261 tcgatcaaga aggaaaatta tctaagctct atacctatca cagcaagcca ggagcaggct
    22321 cacgccatat cattttccat aaccactata aaatcgctta tctcatttgt gaactcaata
    22381 gtactatcga agttttaatc tacgatggcg ttggcgaatt tgtacgtatg caggttattt
    22441 caactttacc agaagcttac gaaggcttta atggaaccgc tgctattcat ctctctaaag
    22501 acggtaaata cctctacgct tctaaccgtg gccatgattc tatcgcagta tataccatcc
    22561 ttgcggacgg tagcttagag ttattagaaa tcgttccaac gcatggtcag actccacgtg
    22621 attttgattt gacacccgac caaaaatttc tcattgttgt ccatcaagac tctgacaatg
    22681 caactgtctt taaacgtaat tgtgacaatg gtcgtctagc agaactctcc aacgacttcc
    22741 atgttcccga agcagtctgc atccgttttg ctccttaaaa caccataaaa aatgaacttg
    22801 gtattttcaa gttcattttt tcttatagtc tatttccgac attaatacgg ttaatggcac
    22861 gttgcaaagc aatcttagca cgacgttctt ggtcaatcaa atgtttgtct tgtgcttctt
    22921 caattgcacg ttctgcacga agtttggcac gttctgcacg actgatatcg atatcacgag
    22981 cacgttctgc agagtcagcg acgattgtga tcatatcatt ggcaatttca ataacgccac
    23041 cgtttactgc aatccagttc acgtgatctt tatcatcgat acgttttacc tttacttcat
    23101 caactgctaa aaccgcaatc atattttcat gtcgtggcaa gatccccatc tcaccatcca
    23161 gagttcgaac cgatacatag ctggcatggt gatcatagac gagaccatct ggtgtcacga
    23221 tctggacagt taactgagcc ataggtcacc tcttaaaatc ccattttttc agcttttgca
    23281 atcacatctt cgatagaacc tacaccacgg aaggcatctt ctggcaagtg gtcgtattta
    23341 ccatcaagga tttccttaaa gccacgtaca gtttcagcaa ctggaacata agaacctggc
    23401 tgaccagtaa attgttccgc aacgttgaag ttttgtgaca agaagaactg gatacgacgg
    23461 gcgcgagcaa ccaaggtctt ttcttcatca gaaagctcat ccataccaag gatagcaatg
    23521 atatcttgca attcatggta acgttgaaga acacgtttta cttcagcagc aactgcatag
    23581 tgctcttctc caacgatttc aggtgccaag gcacgtgagc ttgaagcaag tgggtcaacg
    23641 gctgggtaga tacccaattg taccaactta cgttccaagt ttgttgttga atctaagtga
    23701 gcgaaggctg ttgctggcgc tgggtcagta tagtcatccg ctggcacata gatagcctgg
    23761 atagaggtta cagaaccctt cttggttgat gtgatacgtt cttgcaattg acccatttcc
    23821 gtagcaagtg ttggttggta accaacggct gatggcatac gacccaaaag ggcagatact
    23881 tctgaaccag cctgagtgaa acggaagata ttatcgataa agagaagcac gtcttggcct
    23941 tccacatcac ggaagtattc agcgattgtc aaaccagtaa gggcaacacg catacgtgct
    24001 cctggtggct cattcatctg accaaagacc atggctgttt tctcgataac gcctgattct
    24061 ttcatttccc agtaaaggtc attcccctca cgagtacgtt ccccaacacc agcaaatact
    24121 gaaataccac cgtgctcttg ggcaatgttg tgaatcaatt cttggattaa gacagtttta
    24181 ccaactccgg caccaccgaa aagtccaact ttaccacctt taaggtaagg ggcaagaagg
    24241 tcaataacct tgatccctgt ttcaaggatt tcagaagagg tagacaactc atcaaaagtt
    24301 ggagcttttt tatgaattgg ctgacgctct gcgtcttctg taaaaggagc ttccaagtca
    24361 atggtatctc ccaaaacgtt gaagacacgt cccaaagttt ctttacctac tggtacagag
    24421 attggacgac ctgtgtccaa tacttccatt ccacgagtca acccatctgt tgattccatg
    24481 gcgatagtac gaaccatacc atctcctaac tccaaggcta cttcaaggac gatttttgtt
    24541 tttctttcgt catttttgta gacgacaagt gcattattaa tctcaggaag tttttcccct
    24601 gctgcaaaca aaacgtctac aacgggaccg ataacctgag caattttacc tgaactcatc
    24661 tccttctcct attctatata agatactgtc ggttcctagc tcaactaggt cctaagttca
    24721 ttttcatacg agctggacta gagcctattc taaggcacta gcacctgcta cgatttctgt
    24781 aatttcttgt gtaatagccg cctgtctggc acggttatac tgaattgtca aatcattgat
    24841 gactttctta gcattatctg tcgctgtttg catggctgtc atacccgcag cattctcagc
    24901 tgtcttggca tcgataatgg caccgtaaat catactttct gcaaactgag gcaacaactg
    24961 ctccagaatt tcttctcggc tggtttccaa ttcaaaagtc aagctgtact cttcatccgc
    25021 ttcatttgga tccaagtcaa caatcggaag catttgttcc acacgcattt gactggttag
    25081 cgtattgaca tggtggttgt agcaaacata aagctcatca aagagttcat tttggtacat
    25141 ttcaacagtt tttgaaataa tcttacgaac ttgatcaaag ctaggttggt ctgccaagcc
    25201 acgtaattca taaagtggtt gaataccgcg agccttaaag aaatcagctc ccatcccacc
    25261 gatacagatc atttcaaaac ctttaccgtc tgggtggtat tcttctttca actccataac
    25321 agctttcaaa atagaggaat tataacctcc aaccaaaccg cggtctgaag tgataacgat
    25381 atagcctgtc ttcttcacag aacggctaat caacatcgga ttagttgaag caccagctcc
    25441 attaccatga aggatatctg tcaaaagttt acgcactttc tgagcgtaaa cttggaagtt
    25501 gcgagcagct tcttcagagc gacctagctt agcagccgat accatttgca tggcattagt
    25561 gatttgactc gtattttttg ttgaggcgat ttttgtttta atatcattta gagacactgc
    25621 catctgacac ctctattctt attggaagct agattgattg agaaactctg taatcgcagc
    25681 atccaagact gcttcttctg gcaagtcttt tgtatcacga atggtttcca aaatctctgg
    25741 atgttgagca tcaaagaagg catggaactc ttcctcgaaa cgaacaatat catctactgg
    25801 aacagtatcc aagaaaccat gtgtcaaagc ataaagaatg gttacttgtt tctcaacagg
    25861 taatggtttg tgaacaggtt gtttcaagac ctcaacggta cgacgtccac ggttcaactt
    25921 agcctgtgtt gctgcgtcca agtcagaacc aaacttagta aaggcttcca actcacggta
    25981 tgaagcaagg tcgatacgaa gtgtaccagc aaccttcttc atggctttga tttgtgcaga
    26041 accacctaca cgagatacag atgaacccgc atcgatggct ggacgaatac ctgcattgaa
    26101 gaggccatcg ccaaggaaga tttgtccatc agtgatagaa atcacgttgg ttgcgatata
    26161 ggctgagata tctcctgctt gtgtctcgat aaatggtagg gctgtaattg atccaccacc
    26221 aagttcatca gaaactttag ctgagcgctc aagcaaacgg ctgtggagat agaaaacatc
    26281 ccctgggaag gcttcacgac ctggaggacg acgaagcaag agcgacagtt cacgataagc
    26341 taccgcttgt tttgatagat catcatatac aatcaaaaca tgcttacctt gatacataaa
    26401 ttcttccgcc atagcaaccc cagcataagg agctaggaag agcaatggag atggttgtga
    26461 agcagaggct gtcacaacga ttgtgtagtc caaggcaccg tactgacgaa gtgtttctac
    26521 ttgcgtacga actgttgatt ctttttgtcc aatcgcgacg tagatacaga tcatatcttg
    26581 atctttttgg ttcaagattg tatcaatcgc aatggttgtt ttccctgtct gacggtcacc
    26641 gataatcaac tcacgttgac cacgaccaat cggtacaagg gcgtcaatag ctttcaaacc
    26701 agtttgcaat ggttctgaaa cagacttacg ttgcataaca ccaggagctg gtgcctcaac
    26761 tggacgagtt ttatcagtgt ggatttctcc aagaccgtca actggacgac caagcggatc
    26821 cacaacacga ccaatcagac tttcacctac agggacttcc atgattttcc ctgtacggcg
    26881 gattgtatcg ccttcacgga tatctgtaaa gtcacctagg atgataatac caacgtctgt
    26941 tgactccaag ttttgagcca taccataaga gccgttttca aaattcaaca actctccact
    27001 catggcattt tcaaggccgt gagcacgcgc gataccatcc ccgatatagg ttacaacacc
    27061 tgtttcagtc acatcaaaat tgggtttgaa attttcaatt tgttgcttaa ttaaagcgct
    27121 gatttcttgt gcgttaattg ccaaaagaac accactttct atttcaaatt ttctttaaca
    27181 actttaagtt gttgtttaat actcacatca attgtcttgt gattggcaaa aatgacaaaa
    27241 ccaccaatga gactttcatc gatttgttct tttacactcc ttactttcag agacattttt
    27301 ttctcaatca aaggtagcaa acgagtcttc tgttcatcag ttagaggatg agcagacgta
    27361 atcgtcactt caaatcgatt tgtttctttt tcaagtcggt tcaagcaatc tacaagcaca
    27421 tcataaaaaa gatttgctct gtgattgtag gccagaacct ggataaagtt ttgtaataaa
    27481 ggtgacacag aatcttggaa aaaagcaatt gttttttcct tatccgactc gtctactgcc
    27541 acttgtttta aaaaagaagg cagacctgtt ttttcaacaa cttgcttgat ttgagtcaag
    27601 tctgaaaaga tacggtcttc ttctcctttt tcaagtacca attggacaaa aggcatgctg
    27661 tatttttcaa ttacctttac tgttttcttg tccattaagc ttctcctagc tgatcgatat
    27721 actgatcaat gagtgcttta tgggcatgac tgtcaaggtt ttgtgagatg attttaccag
    27781 ctaagctgat ggtcaaatct gcgacctcac ccttaacact ctgtaaagct tctactttat
    27841 tttgagcaat ttcttgattg gctttttctt ttaagtgtcc tgcttctagt ttagcatctg
    27901 ctaagatatt agccttactt tgctcagctg tttcctttgc attttcaatg attgtcttag
    27961 cttctttacg gctaccagcc aattcatctt cgcgtttttg agccaatact tctgcttttt
    28021 gacgggcttc ttcagctctg tcaatatctg aagcaatttt ttcagctctt tcttcgaaaa
    28081 tgcctgtaat attagaccat gcaaattttt taatcaagac tagcaaaaga ataaaagagc
    28141 cagtgattaa aataaaatta ccaattaatt cacctactgt tacgtgcatc agttactcct
    28201 ttctattcct cttcaatatt aatcttattc cctaaataca cagatgtcaa aagagtaaaa
    28261 acataagctt ggatgcagga aataaagaca gaaaatgcag tccaagccaa attagctcca
    28321 aaggctactg gataccaata aatagcttgg tgggaaagaa gaagtaacaa actcgtcatg
    28381 acctctcctg caaagatatt cccaaaaatc cgcaaagcca aagataagaa gtttgtaaat
    28441 tcttccaaga tattcatcgg tatgacaaaa acaggactca taaaagattt tatacttttt
    28501 ttaaatccac gacgacgaac gctttctata tgtgtcaaca aaatgacaag aaaagataag
    28561 gttaagtcat acggtaaatt agcggttggc gaactccacc agttagtccc atcgatcgtt
    28621 tgaagctttg tcattaagcc aaggttattg gcaatcacca tgaaaaggaa taaacaaagg
    28681 aaaaagagtg agtaatcttt catgtagcgc gaaccaatgt taggttctgt aaatccaata
    28741 acaaagtcat agacatactc aagtacattt tgctttcctt tgggtttcaa ggtcatattg
    28801 cggcttgccc aataaataaa gacaaaaata actcccacaa tcaacaaagt catggctaac
    28861 atagtcagat tgaagataac aggaccaata gagatgattg gattaatact ttcttccatc
    28921 taaaatcctc ccttttcttc tcgttccatg tatttatttg ataataaatg agaagacaag
    28981 agttacaaag aaagttcctt caataaaggc aacacctaaa aacatcaaac tacgaaactc
    29041 agaaagcata tctggttggc gtgctactga tttaaacagt ccattcatca ataaaccttc
    29101 accgacagat acgcccatac aggcaataca taagcctaaa aatgttaaat tcataacaaa
    29161 ttctccttta aaataaaatt tacttactta gtgtagtcct aaaatttaaa tttgtcaact
    29221 tttaaccgct attggaagcg tttaataaaa attatttcca ttttgctaaa tttcaagttc
    29281 aagttagcca tccagaagtc ttctctgggt gacttgtagt ccaagcattt tttaggatag
    29341 ttgttaatcc acttttcgat gaatgcgact tctttgggag tcattttctt ggttccctta
    29401 ggtaaccatc tacgaatgag cctgttgtga ttctcattag ttcccctttc ccaagaggca
    29461 tagggatgtg cataataaat gtgctcctca gaaaatacat tagacaagcg attgaattcc
    29521 gttccattat ctgccgtgat ggaaagaatc ttgtgttgtt ttaagatgag ttttagagcc
    29581 tgattgacca cctcagcact tttatttgga atcaatcgga tgatctgatg tctacttttt
    29641 cgatccgtca agacaagcaa gcagtagttt ttcgctctcg taagtagaac cgtatcaatc
    29701 tcataatgcc cattctccaa gcgaaaattg atagcttcag gccgctgttc gatggattga
    29761 ccagcaggtt taaagttggt gctggcctgt ttcttaagcg cttttccttt tctagggtaa
    29821 agcagatcct gcttgcttta ccccaatttt ccatgatgaa tccaatagta aatggttgaa
    29881 attcccacgt taaccccttt agccataacc atcatttcag gcaaaaattt ttggttatga
    29941 tagtggagaa tcttttcctt tagttccttg gtcacgcttg atctcttgac cgagtgcttg
    30001 cgattatttt cataagactg ttgagcatag tcggcagaat aaacctcttt gaagcgccct
    30061 tttccaagac attttcggac tgtcctacgc ttgattttag tgtggatagt ttgaggagct
    30121 tttccaagta gagaggcaat ttctctattt gattttcctt cttttttcca tctttcgatt
    30181 aagcgacggc tatcgattgt caaatgttta ccttttgtag tataattgtc ttgcatttct
    30241 gtgcctttct tgtgtttgtg gttgaacaac aagtataaca cagaggtgtt ttcttatgcc
    30301 tacaagagct ttcattattt ccattttctt tcggatttca ctctattctg aaaaacttgt
    30361 gtatatttac tgaagctagc aagtcttacc tgtaaattta atgaaagcaa cacaaaatcc
    30421 gagaggggaa tctcggatta atgtcaattt aaaaagatag agagttttta gtttaaataa
    30481 attgttttaa aatatcaaca acatcacttc ttttcttaac ctgataagcc ttgattccta
    30541 attttggagc tacgattata ttgtcctcaa tatcgtctag aaagacacaa tttctaggtt
    30601 ataactggta tttatcgata gttactcata tacatcagtc cacctccata cttatgtgcg
    30661 agcctctctt tgtattatac ctccatactc accttacaga ttcttttggt aataatatct
    30721 ttgcctaatg tagagatagt cttacaaaga aaaaacttcc ttgtagccat gtttctgata
    30781 aaagtccggt gcctggaact gataagtatt gacaaaggca aaacaacaat ttcgattctt
    30841 agcttcactt tctgcctgtt gcaatagttt tgaaccgatt ccttgccctc gcagttcctc
    30901 ttttacaaac aaatactcga tttctagcca atttccaaaa gtctctgcta tcaaacccgc
    30961 aaggagattg cccttttcat cttcgacata aagattaagt ggctcacttt cagcctcttc
    31021 cctttttgaa cggttataaa cacgaatcag attccctatt tcttgcgatt tatgtgattc
    31081 cttattttcc aatctaaagt ataatgaaat gaaataaaac atgcgcaaat cgattaagga
    31141 atttaatcta atttctaata atgtcttaga aatcaaagtt tactatttta acttcaatgc
    31201 actatacatc taatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaggttg
    31261 ctcaaaacac tgttttgagg ttgtagatag aactgacgaa gtcagctcaa aacatggttt
    31321 tgaggttgta gatgaaactg acgaagtcag taaccatata tacggcaagg cgacgctgac
    31381 gtggtttgaa gagattttcg aagagtagca aaatggaaaa aggagtgagt gaagcacatc
    31441 gcctccccac tcctttttct gtttttaggc tgttttttca accttcaaga tttttacatc
    31501 atagctacca acaggcgttt caattgttgc tgtgtcacct gttttcttgc caatcaaggc
    31561 ctgcccaatt gggctttcat ttgaaacctt acctgcaaag gcatccgcac cagctgaacc
    31621 tacgataata taaacttctt cttcgtcctc gccaatttct tggatggtga ctgttttacc
    31681 aatcgctact tcgtcctggg caactgcgtc gctattgacg atttcagcat agcggatttt
    31741 tgtttctaag ctagagattt gtccttcgac aaaggcttgt tcatccttag ctgcttcgta
    31801 ctcactgttt tctgaaagat caccgtatga acgggcaatc ttaatgcgtt ctaccacttc
    31861 tggtcgacga accaatttca attcttctaa ttctttttca agtttttcct tttcctcaag
    31921 gggcatagga tatgtttttt ctgccatttt tctcaacttt cttctgataa tattttctaa
    31981 agaaaattat gtgacgtatc acataatttt agtttgttta gtttaatttg ctgttgacat
    32041 gttcagcgac attgcggtcg tggtcttctt gattgttagc atagtagacc ttgccttctg
    32101 tgacatctgc tacaaagtag aggttatcgc tcttagtttg attgatgctt gactcaatcg
    32161 catccagact tggactatcg actggaccag gcatgagacc tacattttta taaacattat
    32221 aaggtgaatc aatgttggta tcaatcgcaa catcctcagc tagactgata ttttgcccca
    32281 gttttccttg ggcatacaag attgcaatat tactttgaag tggcatatca cgatttaaac
    32341 gattgtagaa tacacctgca atgagcttac gatcttctgt cttggcacct tctttttcga
    32401 ccaaggaagc aatggtcaac aactcattga cagtcaaatt tttagatttg atagtactat
    32461 agtaaggaga taggttctta tccatagcag ctaacatctc atcaatcaag ctctcaatag
    32521 ttgtgctttc cttgatagag tatgtagctg ggaaaaggta tccttccaaa cgataacgcg
    32581 caccgctgtc ttttacaggc aaactttcca gtaaagtagg atatttcgct actgcttgac
    32641 tgataaacgt ctcatcttga actttagcca agaaagcctc cgctgtcaaa gactctttga
    32701 agtcaccttg caattgaccc acagcttgag caatctgatc caaggtataa ccttctggaa
    32761 ttgtcaaagt cgcaagtaca ggttcttgcg gttcatctgt tccacctttt tgcaactctt
    32821 tgagtaagtc ttctgtactc atactctttt gcaaattgta gtaacctgct ttcaagtcgg
    32881 tataattttt atacttggca taaaaactaa aaatcagacc atgctttacc aaaccagctt
    32941 tttcaagcgt cgtaccgatt tcttgaacgt ttgaaccttc tggaattcca accgtcacat
    33001 atttcttaga attagcatcg ataggtaaca aagaatctag cacgtactgg taaccaaagt
    33061 aaccacctgc tgagagcaag gcaaggaata caaggaatga aatcacaaaa gctttcacat
    33121 gtgacttctt ctctttctta ggattaacgg gttttgctcc ttctctacgg ctacgacgtg
    33181 atgtatcgct gatgatatcc actgtttctg tagcaggcgt aggtgtttct ggacctgctt
    33241 gttctgcttt tttctctgcc gtcgtatagg aaacagctac ccttgttggg gtttcattgt
    33301 attctctttc aagtttctta ggtctaacag gacctggacc tggtcttgat ccactttctt
    33361 ccgctggaga agaaggtaca tcttgacttg gatgacttgg aacaccagga gtttctcttt
    33421 gaatctcatc tgctggagaa gctggtacac cttgacttgg gtgagtagac acggtaggag
    33481 cttttctcat aatctcctct accgttgaca aggaatcagc catgagttct tcagctgaag
    33541 gttcatttgc aggagtgcga actactgcct catcttcttt cagaacttca tcatagcctt
    33601 ttactttttc taaatctctc agaatctgct ctttaaagct taatttctct tcttctcttg
    33661 acttttcact caaaagtttt tcctccttgt tgataatcca taatattata tcttaaaagt
    33721 ccaaaaaaag caatctatga tacttttcct aacttatttt ttcatttccc agaccatatc
    33781 ataccatgtt tcccctgcaa aggttgactg ggactggcct tcgttgacaa atccatgttt
    33841 ttcatagtag gcgatgagat agtcatgaca ggttagatta atgccatctc tctcatcttc
    33901 aagagcaact tctttcaagg ctgtcagcaa tttctgaccc agtccgagtc cctgtgcctc
    33961 cttggcaata gacagacagg tcacagagat ataaccacca ggctcatgac tatagtcttt
    34021 tatttcttct gtaaaagact ggtcttgcag atggcggtgc aggccaactg gtccttcgat
    34081 ataacccatg attcttcctt ctttttcagc aaccagaaaa gaggtctgaa tttctctcaa
    34141 atgtgcttca aagacagaag gaggaatggc ttcttcgacc gaaaaatttt caaattcaag
    34201 ttcaacaatc cgatccaaat cttctaatct tgcttgtctg attttcattg ttcctccaga
    34261 taaaagggat taaaccaaat catactatag ccctggctag ttgcatagag caaagttgct
    34321 tcttcatcaa caaaaccgtt catttcaaaa taggaaagca gctcatcagg actctccaaa
    34381 cgaatccctt tgtaatccag ctcaactgcc atctctttca aggctgcaag aagaagtgtt
    34441 cccaagccct gtctctgatg gtcagactcg atgactaaag aatgtacttt tagatattgc
    34501 ggattgtctg actggggact tgataaaata tagcctaaaa gttgattttc atccctagct
    34561 agaagaaagg tatccgcaca cttacggata ctttcttcta aaatatggga aagttgctgc
    34621 ttttcagctg gaaaagacga ggtctgaagt gcccctatct caggcaaatc agacttgctt
    34681 gcctgaatga tcttaattgg aatttccatg ggaacatcct attgaacatt gcttgtcaag
    34741 ttagacaaga gacgctcaaa tgagtattca taggtttgga tgtctcctgc tcccataaag
    34801 acgtaaacag cattgtcatg gtctaggagc ggagaaacat tttcaacagt aatcacttgg
    34861 tgttttttgt tgattttgtt ggctaggtct tctaccttaa cgtcaccatg atctacttca
    34921 cgagccgagc cataaatttg cgctagataa acagcatctg cttggtttaa agcatgggca
    34981 aagtcgtcca acaaggcaat ggttcttgta aaggtatgcg gttgaaagac tgctacaatt
    35041 tccttgcttg ggtatttctg acgagccgca tccaaggtcg caataatttc tgttggatgg
    35101 tgggcaaagt catcgataat cactgtatca ttgacaattt tctcagtgaa acgacgttta
    35161 acaccggcaa atgttttcaa gtgctcacgc accaagttca aatcaaatcc tgctgtgtaa
    35221 agaagaccaa taacggctgt cgcattcatg atattgtgac gaccaaaggt tggaatgtgg
    35281 aattgcccca agttttgtcc acggaaatga acggtgaagg ttgaaccagt tattgaacga
    35341 agaagatcac tagctacaaa gtcattgcct tcaacttcaa aaccataata ataaattggt
    35401 gcatcagacg taatcttacg caattcagca tcttcaccat agacaaaaag acccttggtg
    35461 atttgtttgg catagtcgtt aaaggcatta aaaacatcct cgagacttgt gaaataatct
    35521 ggatggtcaa agtcaatgtt ggtgataata gagtattctg ggtggtaagg catgaagtga
    35581 cgctcatatt cgtcagattc aaagacaaaa tatttggcat tggccgaacc acgacctgtc
    35641 ccatctccaa tcaagaagct ggtatctgta atgtgagaca agacatgaga caacatacct
    35701 gtcgttgaag tttttccatg tgctcctgct actcccatgc taacaaagtc acgcataaag
    35761 ctacctagaa actcatggta acgtttgtag ctgataccat tttggtccgc ataggcaatt
    35821 tcgacgttgt tatctggacg aaaggcattt ccagcgataa tttccatatc accgtctaga
    35881 ttcttttcat caaaaggaag aatggtaatt cctgcctgct caagaccgcg ttgggtaaag
    35941 tagtactttt caacatctga tccctgaacc ttgtgcccca tctggtgcaa catcaaggcc
    36001 aaggcactca tccctgatcc cttaattccg ataaaatgat atgtctttga catgttttct
    36061 cccctattct gtcattctgg tcagattcaa ctcttgggca acccgacgtt cttgttctgt
    36121 ttgtttactt tttttattgt agatttggct cttctttaga aaatcataat tgtttttctt
    36181 tggagcaggt gctgacactt cttcattctt ggtagggata gaatgaactt cttccgccaa
    36241 gatataatga gactgggtca atttttggct atatttgaca aattcaccag gattttcctt
    36301 ttggaaagga gttgtcggtt gattgccctg tctaactaga ctgggctgag aatgacgtct
    36361 cgcaaggctg aaatcctgag ttaggtagtt agcagagcgt ttctttttca agtccgcacg
    36421 cgcttcttca cgcgccacct ccgcatagct ctttccttct tttttaaccc ctaaaggagc
    36481 ctttttaggt ttttcgactt gcttttcaat cggttttact ggtttttctt cagcaatagg
    36541 agcccattct aaataatttt tatctcgata ctcacccttg atattactga tcagatcaga
    36601 ctcatcatag agattcatga ctggcatttc agtcaacatg acctcgtcat ctgacaccaa
    36661 tggaaatcgt tcttgtttca ttttctattt cctttcaaca cttcattata gcgtattgtc
    36721 ttgatttttc aagtgctggc ttcagaaatt cccaaaattt ctctaatttc tgctagggtc
    36781 agactaccac gtgactctgt gccgtccaat acttgtgaca ccagatgttt cttttgttct
    36841 tggagttcct gaattttttc ttcaatggtt cccttggtca ccaagcgata gacctcaacc
    36901 gtttcttcct gacccatccg atgggcacgg ccaatggctt gcgcttccac cgcaggattc
    36961 caccaaaggt caaccaagat cactgtatct gcacctgtca ggttcagacc gaccccacca
    37021 gccttgaggg aaatcagaaa ggcatctctt tctccttggt taaaggcctt ggtcatgtct
    37081 tgtctttcct tggctggggt tgaacccgta attttaaagg aagtcaggcc caagtctggc
    37141 agttcttgtt caattttttc caacattccc ttgaactgag agaaaatcaa gacacggtgt
    37201 ccgccgtctg ccacctgtac cagtaggtct cggagactat ctagtttgcc gctggctccc
    37261 tgataatctt ccataaacag ggcaggagtg tcacatattt gacgcaagcg catcaaacca
    37321 gataaaattt ccacacgact tcgctgaaat tcctgttctg acacttgagc cagatggtct
    37381 cgcatctgtt gtaactgggc aaggtaaata gccttttgct ggtcttccag ttcattttta
    37441 taaaccacct caatcaagtc tggcaattca gtcagaactt cttctttctt gcgtcgcatc
    37501 acgaaaggct tgataaactg agccactcgc tctgctggca atttcataaa ttctttcttg
    37561 cttggcaaaa gtccgggcat gacgatttgg aaaatagacc acaactcacc cagatggttt
    37621 tcaatcggag ttcctgacaa ggcaaagacc gacggcacca caaattgtct caaggtctgg
    37681 gcaatcttgg tctgggcatt tttcatgacc tgagcttcat ctaagaaaag gaagtcaaag
    37741 gccatcccct gataaagctc actgtcctga cggaaggtgg catagctagt cacatagatt
    37801 tgatggctct cggcaagaat ctcctcacga cttgctttca aaccatgaac aacagccaca
    37861 tccaactgtg gggcaaattt ctgaaactca tctgcccagt tgtaaatcaa acctgacgga
    37921 gcgagaatca aaacccgact ttcttttgtc acttgactag tcaaaaaagc aatggtctga
    37981 agggttttcc caagtcccat atcatcagcc aaaatcccac caaaaccata atgatggagc
    38041 atctgcaacc agccaattcc cttttcctga taatctcgca agtcagcctg aacctgagtt
    38101 gcctgtcgag gaaagtcctc tggatgtgtc aaatcctggg ccatattctg gaattcttgt
    38161 gaaaaagaaa cacggtctcg cccttcaaag agatgagcta aactgtaggc caaggatttc
    38221 cgagcctgca aggtcccatc ttttaattca aattgcccca gttcctgtag attttggcga
    38281 attttcttgg tttcttcatc gaaaaagtaa acttgattag acgaatcaat ataaaaatcc
    38341 tgattggcaa ccaaggcctg catggcttgg tcgatttcct cctgggcaat atcttgaaaa
    38401 tcaaactgga tttccaagag acctcccttg gaggcaatct gcacctgagg actcgctagg
    38461 ctataaagct cttctagttt atctgatagg tcaacatgcc cgagtttttc aaagactgga
    38521 atgatatcat gaaaaaaatg atagacagac tccgctttta aggcctgacg ccaagattga
    38581 aaatcggctt caaagcccgc agccaaacag acttggaaaa ttctttcttc taagtccgcg
    38641 tcacttgaaa atggtaattc ttctagctct tgtcggctag atacctgtct atttccataa
    38701 tcaaactgaa tttctaaacg aatccgatta tcttcttccc tgtcaaagta aaaagagggc
    38761 gcaaaagttt tgatttgtag acgttctgga gctgaaacgg tgcccatctg gataaaaaga
    38821 gtcagacagg aggccaattt gtctcgatca ctgctatcaa attgcaggta tttctttcct
    38881 tgttgaccca caggtaacgc tttaatttcc ttgagaagac gcatctgctg gtctgttaaa
    38941 aaataaacct gacctttatg gaaaagtact gctccctgat aaaagacatt gaccctagga
    39001 ctctcactga tttccatttc aaaatagtcc gagtattctg ttactgtaaa ggcaaataga
    39061 ttggcatcag catgcatatc ctgaaaaagc agggtttggt agctatccac ttgatggtca
    39121 aattgaaaat ggggcaaggc catcagtaaa ttcacaccct gctcaaaaaa ggtcagaggg
    39181 aaaaagaggt gccgaccttg gttttggaaa aagaggtctg aaaccagccc ttcctccgtt
    39241 agtccgtgca agaaagtcaa aagttcttgg ctggcatcat caaaggcttc ccaagaaaga
    39301 gactcctcat aaatcttgcc aatcatatac gactttctct gctcgacaat ccttaaaaaa
    39361 agtggaatat cccgaatgac atagtatttt tggctattga tttgaccgat tctcagagtc
    39421 cacaagatat gattggttcc tgcttccacc tgacccacag ctgataactc ataggcgcat
    39481 tctgattttg gagataaaat tcgatccaaa aacttgccac ccaaggtcac cttggtttca
    39541 acagcctctt tttcttcatg accttcttcc agactccaca agatttcctg accacgctca
    39601 tcatttttca gaaaatgctc tagcgctgcc aaatgcacac agtaacccct cttttgaaaa
    39661 aaatcacagg cacaaaaaac caaatcatcc tctaaactat agcgcagttc ttcttctgca
    39721 acgcgagcgt agagccgatt gttcttttcc ttgatgatat caaccttacc agtttcataa
    39781 agggcaacac cttcgatacg aattttcccc ggaatcaatt tagccatatt ttcaccttta
    39841 ccttatcttt ttattatacc atattttcgc ctatgaaaat agccttctag gaagactttt
    39901 ctcctagaag gctggatttt taacgtttgg caaaagtagc cacaatccgc tgacagactt
    39961 cttgcaacag agatttgggc atagctatat tgatgcgggc atggagactt ccttcctctc
    40021 caaaatccaa accacggttg aggataacct tggcttcatt tctcaacaac tcttgcaatg
    40081 tttcatcagt caggtcataa gctgaaaagt caagccaaat caagtaggta ccttgcggtt
    40141 tcatgacctt gattttagtc tcttttccaa atagatccac cacataattg atgtggtctt
    40201 caaagacttg cttgagttcc tctagccaat ctttaccgta tcgataggca gcttctgtcg
    40261 ccaaataacc caagcctgaa atttcatgct gattattggc caacaggcgt ttctggaaag
    40321 ctagtctcaa cttaggattt tcaatgactg cataggaatt ttttgttcca gcaatattaa
    40381 atgttttagt ggcactgctc aagacgatag caaaattttt gaaggcagga ttgatggtat
    40441 tgaaagactg gtgtttgtga ccaaagaggg tcaaatcttg gtgaatctca tccgaaacta
    40501 acaaaacacc gtgtttttgg cagagttggc caatcttctc caacacttct ttttcccaaa
    40561 cacgtccacc aggattgtga gggttgcaaa gaatatagag tttaacctcc tcttccacca
    40621 aatccttttc aagttggtca aagtcaatct caaacagacc atccttttcc actaaggaat
    40681 tagtaatcaa tctacgatta ttcaacttga cactgcgagc aaagggtggg tagacaggcg
    40741 tgttaattaa aaccgcctcg ccttcttttg taaaggtttg aatagctgtt gagatggctg
    40801 gtaccacacc ctcgataaag acaagagcct ctttgtcaaa gttgtaaccg tattgtgtag
    40861 cttcccactt ttgaacttcc ttaattaagt cttcactggc ataggtataa ccataaacca
    40921 gttggtctgc gtaagtttgc acggcttggc ggatttcagg caagaccaca aagtccatat
    40981 ccgctatcca agctggtaga acttcactat ccgtttctgt ttctttccat ttataggtat
    41041 ggtgccctaa acggttgggc aggcttgtaa aatcatattt tcccatcttt gtcttatcct
    41101 tctaaggctt ggcgcaaatc tgcaatcaaa tctctagcat cctcaatccc aatagacaaa
    41161 cgcaagaggt catctgtcaa accataagaa tggcgtactt ctgctggaat atcagcatga
    41221 gtttgagtcg ttggataagt aataagactt tccactccgc ccaaactttc cgcaaaagag
    41281 aagaccttga gactgttcaa aatatgagga atgcgtgttt catcggctac tttaaaggaa
    41341 atcatgcctc cacgaccagt gtagagaact tccttaactg ctggagaatc cttcaaaaag
    41401 gcaaccactt cttgggcgtt agctgttgag cgctccatac gaagagacaa ggtcttgaga
    41461 ccacgaagca actggtagct gtcaaatgga gacaagactg cccctgttgt attgagattg
    41521 taaaaaagct tctcgtatag ttctaaacta ttggtcacaa ccactccagc caagacatca
    41581 ttgtggcctg ctagatactt ggttgctgaa tggagaacga tatctgctcc atcttcaatc
    41641 ggacgttggt agatagggct atagaaggta ttgtccacca ccactttggc acccttagca
    41701 tgagccaatt ttgctagttt ttcgatatca aattccaaca tcaagggatt ggttggggtt
    41761 tcgatataga gaacatccac atccttttct aactcggcaa tcaactcttc ttctgtattg
    41821 gcataggtaa aatggaaacg accttcctgc tccacttggt taaaccagcg aaaagaaccg
    41881 ccgtaaagat cacgcactgc caagacctta cttcctactg gaaagccgct aaaggccagt
    41941 acaatagctg acatccctga gctagtcgct aaggcatagt ctgctgactc aatagtcgcc
    42001 aagacttcct cagccttact acgagttgga tttttagtgc gcgtatagtc aaacccagta
    42061 gatcgaccaa actctggatg ctgataggtc gttgaaaaat gaagcggtgt caccaatgca
    42121 cctgtcgctt catctgactt aatacccgcc tgggccaaaa ttgtgttaat gtgtaattcc
    42181 ttgctcatac aatacctcca aatctatagt aactattgta ccacttattt tcatcaactc
    42241 attttcttct tttcaagagc tagttatagt ttcaaactat ataaaaaggg agtttttcct
    42301 gctcccttta atagactata aaatggtgaa tctcaaaaga cacttcactc tatcatttgc
    42361 tcctgcacaa aacgagcata acgctcatga ttttccagta gttccttatg agttcctgag
    42421 ccagtgattt tcccctcctc taagaagaaa atacaatcca catcttttac cgttgacaaa
    42481 ctatgcgcta taatcacaac cgtcttctcc tttaatacag aatagaggct actgataatc
    42541 gcatactcag aatccgcatc aagattagca gtagcttcat caaatataag aatttcagca
    42601 tcttttaagt aggttctagc tatttgaagt ctttggcttt gcccccctga caagaatcgt
    42661 ccgcgttcac caacttcagt atctagtccc tctttcatgg agcgaatctc atcacctagt
    42721 gatactaagt ctagcacttt catcaattca tcatcaatta ctaagcgatt caaaccgaga
    42781 caaagattgt cacgaatact gccagataag actgcattat tttgtgaaac ccaagcgatt
    42841 ttacttctcc attcttttaa gttaaaatca tatatacttg attgctccat tagaatatct
    42901 cctgaaagcg gtttataaaa ccgctctaac aaacgcacaa tcgttgattt tcctgatcca
    42961 gatggtccaa caaaagcaat ttttgcccct tgaaaattga acaagtaata tcctttaaga
    43021 caggtcgatt ttcatcataa ccaaaataga catggttaaa attcaaccct tgtcctgata
    43081 ccgattttcc tccctcaaat ttttctttag gaactgcaag caagttatcc agtgcaactg
    43141 aagatccctt gctcctagaa taaacagtta caaaattagc tatattacta ataggattaa
    43201 gtaattgaaa gaggtaaatc aaaaacgaaa ccaaggttcc cacagatata tatcctgcgc
    43261 tgacccgata acccccatag gttagcatca cagctatagt cgcaaagata aataagagag
    43321 caaacggggt ctcaaaagaa gtaaccctat ctgatttcag tgaattgttt tgtacccttt
    43381 caatacaatt atccaaaaca tcctgtacac ttttctctgc ttggttagtc ttaattaatt
    43441 catgttcttg aatcttttca gtcaattgcc ctgttaaatt tcctcctgta aacgacgact
    43501 atacttttca ctgatattgg aaaggggcaa gataataaac atcatacaag gaagagtgat
    43561 gaataaaagt agagaaagat tccaatcaag actaaataag actacaatgg aaccaagtac
    43621 cataactaaa ctcagaataa tatttgggaa agtcgtaatt aaaaactcac gaatgacact
    43681 catgtcattg acaatggcag aagtcaactc cccactttgg ctcttatcaa agaaggattt
    43741 ctctgcataa atcaacccct ctatcacttt tttcctgatt tttgctatct ttttttcacc
    43801 cgattgacta aacagatagt aaccaataga agaaaacaag gcttgaccaa taaaaatcaa
    43861 aaacgattga aatactttgg aacctatatt ttcaatagaa ctcccatcta ttaaaccctt
    43921 taagataagg ggaagcaaca aagcaagtag actagacaga acaagtaaga aactccccat
    43981 aatcacctta gtatctactc ttaataattt taatttcata aatactcctt ataatatttc
    44041 aacggataaa gtcgggaata actcaatttg aggataaaat ctaataaatc ttcctataac
    44101 aaaacgcata acatctagga ttttatatac ctgatattat gcgtttttaa gcacaaagac
    44161 ttcttacaca aacttatcta caattagatt ttatttgaca tgttttgcca attcttcttg
    44221 ggctttttta ttggattctt ctttttcttt caaccatttt tctctggctt ttgcatattc
    44281 gtctgttgtg acaatcttat cttgtacttt gaggtattta tatgattcaa ccccttttgt
    44341 accggttaaa ccataggcag cagcaaatgg tacggttctt ctcaatgatg gtgttccccc
    44401 acgcgaaaca cttggaagaa ctaaagaact atcaatcaac caagcttgaa tatcagcata
    44461 tttctcataa cgtttggctg gatcttgctc tttattagct tcttccaaca tttgagtata
    44521 gacatccagt ccaactgcct tagccttgtc attggcttct ccaggctcta gtccaagatt
    44581 ttgtagaact cctccactat tagtattaaa aatatcgaga taggttgacg ggtcttgata
    44641 atcaggtccc caaccgccat gatataaatc atagtctttc tgagcagctg tttgagcaaa
    44701 gtagcctgaa ctgtcaaact catctgatgt taattgctga atgtcaatca ctacattatc
    44761 agaacctaaa acagattcaa ttgattgttt gatagaacta actccttgta tgcctacttt
    44821 atctgttact tccacagtct tatccaagtg gattgggaat tgaacaccct ttgcttcgag
    44881 ttctttctta gcttccgcaa acttagcctt ggctttctca ggattgtagt aagggtcttg
    44941 accatccgca aagttgatac cttgccattc cttaccatag ttgaccatct tagaggctac
    45001 aacttcacca aagtcttttc ccttgatact gacaaagttt ggaggaacca ctaggttacg
    45061 caaaatcttt gttgcacctt ctttcccttc agactgagcc ccataagatg ttctgtcaaa
    45121 agcaaaattg atagcctgac ggaagttttt attgagaact gcttcctgag tcgatttctt
    45181 ttcaatgtca cttgttttag aagtataatt gtaagacttc ctatctaggt taaaattaaa
    45241 gaaatatgaa gttgaatttt gcatactata gatgatattg tttttgtatt tttctttaat
    45301 cccttcatag ctggagctgt taggaaaaag acgagccgta gtataagcac cagctgtaaa
    45361 attacgttcc agtgattctt ggtcgctacc atcatagtag gtcaatttca catcgtctac
    45421 aaagacattc ttagcatccc agtaattagg gtttttctta tattcaatag cagattttga
    45481 gacaagtgct ttcatcaaga aaggtccatt gtacaaaata ctagatggat ccgccttccc
    45541 aaaatcatcc ccttttgatt tcaggaaatc tgcattaaca ggaaaaagta tcgttgcaag
    45601 tgtttttgaa ttccagtaaa gttctggttt aaccaaagta tattgaaccg tttggtcatc
    45661 aagtgccttg acaccgacag ttgaaaagtc gcttgtttta ccagtgatat agtcatccaa
    45721 accagcaaca gagtcctgca ctagatacaa ggcttctgat tttttatcag ctgcatattg
    45781 caaacctgtc acaaaatcct gggcagttac aggcgcatat tcttctccct cagaagtaaa
    45841 ccacttggca tccttacgaa gtttgtaggt ataggtcaaa ccgtcctgag aaacagtcca
    45901 atcctctgct aatgatggaa taatattccc atattggtca ttttctaata acccgtctac
    45961 caaatttgca acaatatcgg atgttgctgc gcggttttct gctagatagt tcaagctaga
    46021 tggatcactt gaataaacat agttgtaggt ttttgacgcc gtgctagaat ttccacacgc
    46081 gctcaataaa actcctgtac ccaggacaag acctgccaag gttagatatt tgctcttaga
    46141 ctttttcatt tccagaacct cctgctttaa atatttgttt tattatacaa ctcttggttt
    46201 gtttagtcaa ttgttttttc caaaaaatca aaaaaacctc attttctatt tttgaaagat
    46261 aattttagct attttgacgc taaaaaagga ataagtttca agttctccta aaagattgtt
    46321 caacttattc cttttattta taaatgctac cttacgaaag cttaaatttt gctcgcaggc
    46381 gatctgcttg ggcttttcct attaccttat ctaataaata ggtacgcaga ctcataacca
    46441 tataaagtcc accccccatg gcaccgacaa gagctacata aaagaagctc cacaaacgtc
    46501 cacttggttg gaagaaaaat cctaacagcc actggatggt tcctattaac agaaacatga
    46561 ctagggtcag caaactgatt aaaatggttc gcttcaaaat caccttgcgc ttgacaccag
    46621 ttactttaca aatatcccga tacatcaaga cgttaggaat gatgagagca atggttgttg
    46681 aaatcaaagg accataactg tggaagaggg cgatggtagg tagttgcaag actagcttgg
    46741 caatagaacc atagataaaa tagagaacgg ccttgcggtt gcggaacatg gcctgaagca
    46801 ttggagacaa gaccatgtac aagcctaaaa taatagactg caaaactgca aagacaaata
    46861 agcccagagc caaactatct ggcttaccat agaagaccgt ataaagaggt tctcctacca
    46921 taaccactcc aaccgttgct ggtagcaaga acataaagag tagggtgaga ctgtcctgaa
    46981 cgagacgaga agccgctttc aagtccccct tgacatagtt ttccgtcaaa agtggcaaac
    47041 caacactccc aatcgaaacc cctacagaaa tcaaaatcat cgtgatttta ttaggattgg
    47101 ctgagaaata agaaaacatg acaaccaagt cctcattgct gtagttggta aaccagctca
    47161 tactattgat aaaggtcagc tgatccaaaa tctggaagag ctggatggca gaccctgtca
    47221 ggataaaagg aatggcttcc ttaatggtat caaccaagag acgcttactg ttaatcttat
    47281 ctcctgtttc aaagactctt ttgagtgaac cttcttgggc aaggaaataa atcaagactg
    47341 caaaactggc taccataccg acaaaggcag caaaggttga ttgggtaacg gctgctagat
    47401 aatctcctga accgagcttc ataatgataa aggttgctag gagcatccag ataacacgaa
    47461 tgacctgctc agcaatttgg ctcatggcat agggtttgag gttattcatc ccttggaaaa
    47521 atcctcggat aacactcata gacgggaaaa tcaagactcc ccaagccaag ctttgcatga
    47581 ttgggatcaa gtctttgccc acgccagaca agtctgctag ccaaggagca aagacataca
    47641 agactaaagc aaaaaccagg cctagtcctg tcataaagcc taagaagctc cgaatcaggg
    47701 caaagctatg ctcttcttct cgcatggtat tatacttggc aacttgcttg gccaccgcaa
    47761 ctggaatccc cgctgttgaa accaacaaga accaagcata gatattgtaa cccatggtaa
    47821 agagaccatt tgccttagct gcataagccc ccatccagat gtaccaaggg ataatgtaaa
    47881 cagccccgag taggcgactg ataaagttac tagccgttag ccaagcagtc ccccgtaaca
    47941 tctgggcctg ctggtgattg ttttcgtgcg acatagattc ctcattcaat tttgataact
    48001 aggaaaaact ccttatcttc cattataaac ttttccttgt tacttgtaaa tttacgactt
    48061 tcggtttaca atagaaagta tgattaagat tgaaaccgta ttagatattt taaagaaaga
    48121 tggccttttt cgcgaaatta ttgaccaagg tcattaccac tacaactaca gcaaagttgt
    48181 ttttgatagc atcagctacg atagccgaaa agtaacagaa gacactcttt tttttgcaaa
    48241 aggcgctgcc tttaaaaaag aataccttct ttctgctata acacaaggat tagcttggta
    48301 tgtagctgaa aaggactacg aagtcggtat ccctgtcatc attgtgaacg atataaagaa
    48361 agccatgagt ttgattgcca tggagttcta tggtaatcca caggaaaaac tcaaactcct
    48421 tgcctttact ggtactaagg gtaagacaac agcagcctat ttcgcctata acatcttatc
    48481 tcaagggcat agacctgcta tgttgtcgac catgaacaca actcttgatg gcgagacttt
    48541 ctttaagtca gcgttgacaa cccctgagag tattgacctc tttgacatga tgaatcaggc
    48601 tgtgcaaaat gaccgtaccc acctcatcat ggaagtctcc agtcaagcct atctggtcaa
    48661 acgtgtctat ggtctaacct ttgatgtggg agttttccta aatatcagcc cagaccatat
    48721 cggcccgatt gaacacccta gctttgaaga ctatttctac cacaagcgtc tcttgatgga
    48781 aaatagccga gcagtcatca ttaacagtga catggaccac ttctcagtct tgagagaaca
    48841 ggttgaagat caagaccatg atttctatgg tagccaattt gataaccaaa tcgagaattc
    48901 caaagccttt agcttttcag ctacaggtaa actcgctgga gattatgata tccaactcat
    48961 tggcaacttc aaccaagaaa atgcagttgc tgctggactt gcttgtctcc gtctcggagc
    49021 aagtcttgag gacatcaaaa aaggcatcgc tgcaacccgc gttcctggtc gtatggaagt
    49081 cctcactcag aaaaatggag ccaaggtctt catcgactat gcccacaatg gggatagtct
    49141 gaaaaaactc atcaatgtgg tggaaactca tcaaaccgga aagattgctc tggttctggg
    49201 atcaacagga aacaagggag aaagtcgtcg taaggacttt ggcctcctcc tcaatcaaca
    49261 gcctgagatt caagtctttc tgactgctga tgaccctaac tatgaagacc caatggccat
    49321 tgcagatgaa attagtagct acatcaatca tcctgttgaa aagattgcgg atcgccaaga
    49381 agccatcaag gcggcaatgg ctatcacaaa tcatgaatta gatgcagtta ttattgcggg
    49441 taagggagcc gattgttacc aaatcatcca gggcaagaaa gaatcctacc caggagatac
    49501 agccgtcgca gaaaattatt tataagaata gaaaaaatca agggaaaatg aaacccttga
    49561 ttttttccta ttatttagta aaaacgtttt tcaaaccttc tacagcacct tttgcgtctt
    49621 ctacaacgtc ttttgcctta gcaactgttt tttcaacagc tccttcaagt tctgtcttgc
    49681 tgtctccagt aactttacca aaaccttctt tgacagcgcc tgttgcttgt tccaatttgt
    49741 tttcaagtga catatgattg tctcctttag tttattccga tatgtgttac cggttacata
    49801 tagtttatac cgaatactaa ggaaagtcaa acaatgtgct cagaaacaag aaatcacgct
    49861 aagtagaaag ttaatctctc cttatcaaaa tcgatagcca actcatactt tctatcttca
    49921 ttttgcacaa tatagcctaa gacaaccaaa ctgtccacaa agatatcacg gcatttctgc
    49981 ataagctggt cttttttgag aaatttcaac aaaaaagccg tcatatactt gagggcatac
    50041 tcaggattaa catctcctaa aatgtcatag agctcctgct gtttttctgt caaaggatac
    50101 tgctgtttga ccttgtaaaa ataattggac agggtcattt taatgcgcgc aaagtccgtc
    50161 tttcaactaa aatagctgca ttgatttgat tgcgcaattc cgtctcaaaa ctctgctcca
    50221 acaaggcttg atagaccgga ctagcttctc tgacaaaaat ctcttgatcc agttcaagac
    50281 tatcaagtga ttcaagcgta ggaaaattga ggtaatagcg cttattttca cgtagaatca
    50341 agcctgcctt tatatactct tccatgagtt tatcaactgc aacatctgga aattgagcct
    50401 taatttcccg tagaatcaca tcctcatact ggtccagata gcggatcaat tctccaaaaa
    50461 tggctgtctc gtcaaacgag atggattaaa aatctgaatc atgaagattc ctttctttac
    50521 attgtaacag aggcgatgct gccaactgac taggattggt cccagcttgg ttcagaggaa
    50581 caggcagacc tagttctatg taatactccc tccaaaaatc actaatctcc tgttccccat
    50641 ctccaaattt cataggaata gtttcaaaaa taggtaggat ttctgctata tactgggagc
    50701 agtagaaacc agctgcatct ggatagaaag aagcattgta gggtgctcca agatgtctgc
    50761 aagctctttc cttcaccgac tggatatcca tttctgggta aacatagagg tcgtataaat
    50821 gattggactc aaagaagtct gccggttctt gacagacaac accagcctgt ccactagcat
    50881 gataaatcat cccatccaaa taaatggcaa catggctata gttacctgtg gaagtctgga
    50941 tggcctgtcc catgtctgac ccatctctca caaaaatcaa atcgccattt tctaacatac
    51001 ttcactccta gaaaaaaagg agccgaaact cctttcgata taaggcaaac tagactttcc
    51061 gattttgagc tgacacccaa aatcttacgc attaaagctt tcagttaatt gaggtaccac
    51121 ttgtttctta cgtgaaacgg caccagcaag gaaggcatga ttgttttcaa gtttgaaatt
    51181 gaaagccgct tcgaccttgt ccatattggc accaagagcc aatatttctg agtttgagtt
    51241 gacgatatct gtaatcatca agacaaagtc agagtagccg tttgattcgt tggcagcttg
    51301 cattgcagct tcaatttctg cttggcgttc caaaacttca gcgatgtcaa ctgtgttcac
    51361 ttgggcaaca cggacattat ttccgttgag ttcaaaagtc ttagcatcga tgtcaatcaa
    51421 ttcttcagca gatttgctag ccaagttggt accagctttc aacattgcca aaccatattc
    51481 ttccaagttt acaccagcca attcagccaa ttcaggagca atgattttat ctgttgggtg
    51541 tgttgttggt gatttcaaaa gaagggtatc tgaaatcaaa cctgaaagca tcaaacctgc
    51601 aatctcttta ggcacagcta caccatgttc tttgaacata cggtaaacga ttgaagacgc
    51661 tgatccaact ggctccaaac gcatgtaaag tgggcttgca gtttcaaagt tagccacacg
    51721 gtggtggtct acaacaccgt aaacttctac ttcagcgata tctgatacag attgttggaa
    51781 ttcattgtgg tcagtcaaga taacttgctc tgccccctct gctttggcag aagtgataac
    51841 acgtggtgct tccacaccaa aatagttcaa gacaaaggct gtttcttcat ttggagttcc
    51901 aagggcaaca gcttccgtat ccaaaccgta agcttctttt gcaaggtagg caaaagctac
    51961 agatgatccg atggcatctg agtctggatt ttggtgacca aatactagaa tcttggacat
    52021 gataatacct cattttgttt attttcttta ttgtagcatt tttttcgctt tttgacaaag
    52081 gtaagaggag tcaaaggact ccccacgatt cttcaaaata actgagtaaa tttctatctt
    52141 gattttcaga taaaaattct tccttctgtg gcctcttctt acgcttgaga agagcttcag
    52201 ccgacatggc ttcttcctta ctggcaaaac cttgagcata gataagtttg actggcaagc
    52261 gtgctcgtgt atatttggct cccttcccac tattgtggat agcgaggcgt cttctcatat
    52321 cagtcgtata gcctatatag taggatccat cacgacactc cagaacgtac atataagcct
    52381 tatgatccat aataaatctc ttcgatttcg ggcgtataag agccatcatc attgtggaca
    52441 atcaaaggag gtaagacctt aaagccactt gttgagccat ccttgatcgc ctcaatcaaa
    52501 agcatattgg cttccttttc tctttttgga taaacaaact gcaggcgctt aggggctaga
    52561 ttatgtcgtt ttaacgtatc caaaatatcc agaagtcgat caggacgatg aaccatggcc
    52621 aaacgcccat tagacttgag aatactctgg gcactacgac agatttcttc caaattagtc
    52681 gtgatttcgt gtcgagccaa gagataatgt tcactctcgt tcagattaga ataaggattc
    52741 accttgaaat agggtggatt acacaaaatc atatccacct tactcccctg aatgtgagca
    52801 ggcatatttt tcaaatcatc gcagatgacc tgcatttgct cctctaatcc attcaaacgg
    52861 acagagcgtt cagccatatc cgccaaacgc tcctgaatct caacagacaa tatctgtgct
    52921 tgagtacgag tgctagcaaa aagccccact gctccattcc cagcacagaa atccacaatc
    52981 aaccccttct taggaaaacg tggaaatcgt gataagagaa cactatccac cgaatagcta
    53041 aaaacctctc tattttgaat gattttgata tctgtcgaaa agagctggtt aatgcgctct
    53101 cctgatttta ataattgttc ttcttccatg gtcctattat agcaaattca tattaacatt
    53161 acaaaaaata taaaactcta aactacttct tcttttttaa atggtgcagg gcttctccag
    53221 tccagattgg tagcattcgt cgaaagggag caaaaccgta gttaaagcgg tcgcttgaaa
    53281 agcgtctccg tctaggaaac tggtactttt cttcctccaa agtgcggata gaaagactgg
    53341 ctttccccgt aaattcatct aaatccacta cctgaacttg aacctcttca tcgactttca
    53401 aggtttcgtg aatattttca ataaatcctg tccgaatttc tgaaatgtga atcagccccg
    53461 tatcacccgt ctctaactca acaaaggcac cgtagggctg aatccctgta atacgcccct
    53521 ttagcttatc accgattttc atcttagtcc tcgatttcaa tagtttcaat tacaacatct
    53581 tcaactggct tgtccatagc tcctgtctca acagcagcaa tgacatccaa gacagcgtaa
    53641 gatgcttcat cagctaactg accaaaaacc gtgtgacggc ggtctaggtg aggtgtccca
    53701 ccttgattgg catagatttc tgcaatcggt tctggccaac caccacgagt aatttctttc
    53761 ttagaataag gtaggtgttg gttttgcacg ataaagaact ggctgccgtt ggtatttgga
    53821 ccagcatttg ccatggaaag agcaccacgg atattgtaaa gctcttctga gaattcatcc
    53881 tcaaaagatt cgccgtagat tgactcgcca cccataccag ttccagttgg gtctccacct
    53941 tggatcataa agtccttgat aatacggtgg aaaatgacac catcatagta gccatctttt
    54001 gaaagagata caaagttagc cactgtttta ggagcatgtt cagggaaaag cttgatacgt
    54061 aagtctccgt gattggtctt aatagtcgca agaggacctt ctactgtttc aatgtctact
    54121 tgtggaaaat gcaattcttt ttctaccata ccaaatactt ctaaggcatc aaaaatgcca
    54181 tcttcttcta atgtttttgt aatataatct gctttttctt tgattttatc atgagaaatt
    54241 cccatggcaa cgctgattcc agcataatca aagagttcca agtcgttgag accatctcca
    54301 aaaaccatga ccttctctgg tttcaagcca aggtgttcca caaccttttc cacccccgtc
    54361 gctttggagc ctgaaatcgg cacaatatca gacgaatgtt gatgccaacg aaccatgcga
    54421 agtttgtctg agagactgtc aggcaagtgc aagtcatctc ccttatcttc aaaagtccac
    54481 atctgataga tatcttcttt ttcatggaaa tcgggatcta catctaagtc gggataaatt
    54541 ggattgatag cttcactcat catatcggtg cgagtcgaca acttggcatc atgactccca
    54601 accaagccat actcaattcc ttcttgctta gcccaagaga tatactcctc aacatatgac
    54661 ttttcaatct gatgctgata aatgacctga ccttttttat cttcgatata agccccattc
    54721 aaagttacaa aaaagtcagg cttgagatca cgaatctctg gaacaacacc aaaaatgcca
    54781 cgtccagagg cgattcctgt taaaattcct ttttcacgca actgtttaaa aacagtggga
    54841 attgtagttg gaataaaccc tgtctttgaa ttccgcaatg tatcatcaat atcaaaaaag
    54901 acaatcttga tcttctttgc cttgtatctt aatttcgcgt ccatctcact acctctttca
    54961 atctaactct ttccattata tcataaagta ggcaaatccc ctattttcaa aaagtttatc
    55021 atttttattt taatttcttg gatgagaaaa aagacatatt tatgaaaaag ctccatcgtg
    55081 cttttaatgt gttctcttgt tttcaaactc gtaaaaaggg agccactgag cctaactcgc
    55141 tctctcattt caaagcttgt gaaaaaagac ccgttggggt cttaattcgc tttcttgttt
    55201 tcaagctcat gaaaaagaga cccaaccggg tcttttcttt aatcttcgtt tacgaaaggc
    55261 atcaaagcca ttacgcgagc gcgtttgata gctgttgtta ctttacgttg gtttttagct
    55321 gaagttcctg ttacacgacg aggaaggatt ttcccacgtt ctgaaacgaa acggctaaga
    55381 agctcagtat ctttgtaatc aacatattca attttgtttg ctgcgatgta atcaactttt
    55441 ttacggcgtt tgaatccgcc acgacgttgt tgagccatgt tttttctcct ttataagttt
    55501 agttgtccat tagaatggta aatcatcatc tgaaatatcc aatgggtttg ttgctccaaa
    55561 tggattttca ttacgtgaaa agtctggtac tgaatttgta ggtgctgaat agtttgcagt
    55621 tggtgcagag taagctccac ctgtgtggcc ctcacgcaca ctacggcttt ccaacatttg
    55681 gaaattctca gccacgacct ctgtcacgta gacacgttgt ccttgctggt tatcgtaact
    55741 acgagtctgg atacgacctg tcaccccgat aagtgagcct tttttagccc agttagcaag
    55801 attttcagcc tgttggcgcc acataacgac attgataaaa tcagcctcac gttcaccatt
    55861 ttgactctta aatgtacggt ttactgcaag agtaaaagtc gcaactgcta catttgatgg
    55921 ggtataacgc aactcagcgt cacgtgtcat acgccctaca agtacaacat tgttaatcat
    55981 agtttacctt cttacgcgtc aattttgacg atcatgtgac gaagaatgtc agcgttgatt
    56041 tttgaaagac ggtcaaactc tttaagagct gcatcgtcat ttgcttcaac gttaacgatg
    56101 tggtaaagtc cttcacggaa atcttggatt tcgtatgcaa gacgacgttt ttcccaagtt
    56161 tttgattcaa caacagttgc accgttgtca gtcaaaatag agtcaaaacg tgctaccaaa
    56221 gcgtttttag cttcttcttc aatgtttgga cgaatgatat aaagaatttc gtatttagcc
    56281 attgatatgt tcctcctttt ggtctaatga ccccaagact ttgcaagggg taagtgaggt
    56341 tcgctcacaa taaactatta tactagaaaa aattttttta cgcaagtaaa aacactagaa
    56401 ttcgaaaaaa cgccacatgg gcgttttcct gttcttatgg tttgatacgg tgcaacatac
    56461 gtgggaatgg aatagcttca cggatatgtt ttgttcctgc tgcgaaggtt accatacgtt
    56521 cgataccgat accaaatcct ccgtgtggaa ctgtaccgta tttacgaagg tcaaggtaga
    56581 attcatattc tgtacgatcc atgccaagtt catccatctt agcgacaagg gcatcgtaat
    56641 cttcctcacg catagaccca ccgataattt ctccatagcc ttctggagca agcaagtctg
    56701 cacaaagcac gcgctctgga tttccaggaa ctggtttcat gtagaaggcc ttgatggctg
    56761 ctggatagtt catgacaaat gttggcacac caaagtggtt tgaaatccaa gtttcgtgtg
    56821 gtgacccaaa gtcatcacca tgctcaagat gctcgtagtc agcatcttca tcattttcat
    56881 gctcttgcaa gaggtcaatg gcttgatcgt aagtgatacg tttgaatggc tctgcaatgt
    56941 agcgtttcaa gagttctgta tcacgttcca aggtttccaa ggcttgaggc gcgcggtcaa
    57001 gaacaccttg tagaagagct ttcacataag cttcttgcaa gtcaagcgac tcatcatgtg
    57061 tcaagtatga gtactcagca tccatcatcc agaactcagt caagtgacgg cgtgtttttg
    57121 atttttcagc acggaaaact ggaccaaagt caaagacacg accaagagcc atagcccctg
    57181 cttctaggta aagctgacct gattggctca agtaggctgg cgttccgaag tagtcagttt
    57241 caaagagttc tgtagaatct tctgccgcat ttcctgaaag aattgggctg tcaaacttca
    57301 taaaaccgtt cttgtcaaag aactcataag ttgcatagat aatagcgtta cggatttgca
    57361 acacagctac ttgcttacga gagcgtagcc acaagtgacg gttatccatc aaaaagtctg
    57421 ttccgtgttc ttttggtgtg attgggtagt cttgagattc accgatcact tcgatgtctg
    57481 tgatgtccaa ctcatagcca aatttagaac gttcgtcctc tttgacaata cctgtcacat
    57541 aaacagacgt ttcttggctc aagcgtttga taacatcaaa cttctcaagt cccacttctt
    57601 caccaaattt ttcgacaaag tttggtttaa aagccacacc ttgaaagaag gctgttccat
    57661 cacgcaattg taagaaagcg atttttcctt ttcctgattt gttggcaacc caagcgccaa
    57721 tcgtcacttc ctgaccaaca tagtctttta cgtcaataat cgttacacgt tttgtcatta
    57781 tttttccttt tcttttttat tctttatggc aaaccacctc tatattgttc ccatccaggt
    57841 caatcataaa agcagcatag taaatcggat gctcacttcg ataaccagga accccattgt
    57901 ctcgcccacc tgcctctatg ccagcctcat aacaagcctg aacttcttcc ttattttctg
    57961 ctaaaaaagc aaaatgaaca ggatcttgtg ttccctgagt cagccaaaaa tcaccaccag
    58021 gatgagggct gttcggggat agaaaactaa ttagagaact agtcttaaaa gccaatttat
    58081 agtccaaagg agcgagaaaa ctcctataaa atccttctga aatttgtaaa tcctttacct
    58141 taatctcaaa atgatcaatc attctcacta cccataaatg ctttcaagcg ttcgactgct
    58201 tctttaagcg tgtctaggtc tgtcgcatag ctgaggcgga cattttctgg tgctccaaat
    58261 ccagctcctg ttaccaaggc cacttcggct tcttctaata tagcagttgt aaagtctgtc
    58321 acatccgtgt agcctttcat ctccatggcc tttttgacat ttgggaatag atagaaagcc
    58381 ccttgtggtt tgaccacttc aaatcctggc acctctgcaa ggaggggata gatggtatta
    58441 agacgtttct caaaggcctg acgcatgctt tctacagtat cttgctcacc tgatagagcc
    58501 tcaactgctg catattgggc tactgctgac ggattcgaag ttgtttgacc tgcaatcttg
    58561 gacatggcag cgataatgtc tgcttctcca acggcataac caatccgcca accagtcatg
    58621 gcataggttt tagacacacc attgatgacc actgtttgct tgcgaatcgc ttccgatagg
    58681 ctagaaatcg gtgtgaactc atgaccatta taaaccaagc ggccatagat atcatctgct
    58741 aggatgagaa tatcattttc tacagcccag tttccaattg ccaagagttc ctcacgggtg
    58801 taaatcatac ctgtgggatt agatggcgaa ttcagcacca aaaccttggt cttgtcagtg
    58861 cgagctgctt ctaactgctc tacggtcacc ttaaagtgat tgtcttcctt agcagaaaca
    58921 aagacgggaa cgccttctgc catcttgacc tgatctccat agctaaccca gtatggggtt
    58981 gggatgatga cttcatcacc tggattgacc acagccataa agaaggtata gagagaatat
    59041 ttggctcccg cagcgactgt cacttgattt ggcgctacag aatagccgta aaagcgctca
    59101 aagtagctat tgaccaccgc cttaagctct ggcagacctg aggttactgt ataaaaagaa
    59161 gcacgcccat ctcgaatcga tgcaatggcg gcatcttgga tatttttggg agtagtgaaa
    59221 tctggctcac ccaaggttag agacaaaata tctctgccct cagccttcag tgctttggca
    59281 cgggctccag cagccaaagt cacactttct tccatttcta aaacacggtt ggataatttc
    59341 ataggccctc cttgttgacc aatgctcctg tttcaaaatc tactagataa aaatcagatc
    59401 ctgacttgac ttcccagatt ggcttatctt gataacgacc aaagataatc ttgtcaattt
    59461 cgccagctcc cttttcctta gaaaccgttt ctgctttttc ttgtgaaaca ccctgattta
    59521 gctgataaac gtaaatctta tgatcatctt ttccaatcag aacagcaagt gcttcttgct
    59581 gtttattacg accaagaacg ctgtaataag attccaagcc attgtataaa tcaacctgat
    59641 cggcctgctc taatcctgca tactgctgag ctaatttttc tccttcactt ttagctgttt
    59701 gatagggttt catgctaaga gaaaccatat acagaaagga agcactgata accacaaaca
    59761 aaatcgtcat ccctagacca tactgccaca gtagattatt ttttgctttg ttttgtcttt
    59821 ttttcactcg tctattttac catctattaa gctttattac aagtgaatat aagaatactc
    59881 ttcgaaaatc tcttcaaacc acgtcagctt tatctgcaac ctcaaagctg tgctttgagc
    59941 aaccaattct atttctccct tcaaacaaaa ccgattttga aagtgaaaca gttcttactt
    60001 tttcagtcac aagtgactag agtttcagca attttataat tttcaaataa actctgagca
    60061 aatttcttgc aagttgtttt gctttgttgt aatatatttt ataacaacga gaaaattctc
    60121 gtaaatttaa gaaaaaggag acacatcatg tctaaaaaag tattatttat cgtcggatca
    60181 ctacgccaag gttctttcaa ccaccaaatg gccctcgaag ctgagaaagc acttgctggt
    60241 aaagcagaag ttagctacct tgattattca gcccttcctc tcttcagcca agatttggaa
    60301 gttccaactc atccagctgt agcggcagct cgtgaagctg tccttgctgc ggatgccatc
    60361 tggatcttct ctccagtcta caacttctct atccctggaa cagtgaaaaa cttgcttgac
    60421 tggctatctc gtgcccttga cttgtctgat acacgcggcg cttctgccct tcaagacaag
    60481 ttcgtcacag tatcatctgt agccaatgca ggtcacgatc aactcttcgc tatctacaaa
    60541 gacctcttgc catttatccg tacacaaggc gttggtgatt tcactgctgc acgtgttaat
    60601 gactctgcct gggcagacgg aaaattggtt cttgaagaaa cagtcctaaa ctcacttgaa
    60661 aaacaagctc aagacttgat cgaagctatc aagtaactaa cactcaataa aaatcaaaaa
    60721 gcaaactagg aagctagccg caagctactc aaagcactgc tttgaggttg tagatagaac
    60781 tgacgaagtc agtaacatat atacggtaag gcgacactga catggcttga agagattttc
    60841 gaagagtata acataataaa agcgaacaag actacttttc tgacgctcag aagactagct
    60901 tgttcgcttt tttctcattt ataaactaaa atagctgatg atacatattg ccaaatacaa
    60961 aatatctgat ttctatactt cctttacaaa aaccaatccc tgtggttgtg acaaatcttc
    61021 tcggtaaaca aatccagcaa agttcaagcg acgtgcttcc cccacagttt gtacttgatt
    61081 ttctattaaa gctgttagaa aggccccgcg cgctttcttg gagatagttg agtgaatctt
    61141 cagctgaccg cctctatcct ccatgaattt gaaggtcacc atctttgctc tgatttcctt
    61201 agaaaataca gtctcaaact ctgatgacaa gagagagaaa atcacttctt ccttcttcag
    61261 agcttcatca tagactgcct tccaatggct cttcaaagtc ttaccagcaa cttttaattt
    61321 catcaaaaaa tccaaacggt gaggagccat gggtgacaag gctggaacaa caccgtacaa
    61381 agccgaggta atgaagacat gattttcaag ataatcttgt tccgcctcgg tcagcttatc
    61441 tctcttaatg ttgcggtaca taagcccatc aaaaagtttc aaggctggat agtgttgagt
    61501 agtttgcctt ttcaaagctt ggatattttg aaattcttcc gccgctttct cagctgatac
    61561 cttgtagaaa ctctccaatt gactggcaga atagagagcc aaggcatcaa gcacggcctg
    61621 actttctggt tttaaagaaa ttgcctcgat acttggcaag tctgtgttca tttcttttgc
    61681 tgttgggatt aaaattttca tattgatagt gtagcatatt ttttagccac aaccaagaaa
    61741 ttcatttgaa aaacctcggt ttgaccgagg tttttctatt tatttgggcc atcctaacca
    61801 gacagccacg agaacaaggg ctgtgccagc taaacttgtt aagatagata agaatttatc
    61861 ttttttctcc ttgaactgag aaaaacctat cttcaaagcg agcagtccga gtagcattga
    61921 agcaaccatc aaataaaaac ccatttcttt gtcctccatt aggcttaatt taccttatta
    61981 taacatatac tttctgaaaa aaacctattt ttaccgtagc ttaaaggtct tgagataatt
    62041 gtcttttcct acttgacctt cgaaggtttt accattttca aggtaaggaa ggtcatcgga
    62101 tactgaagcc ttgaccttgt atatcttgcc atcaacttta aagaagtaga cagtgtctcc
    62161 cttgataaca gctgatttga ggtctgctac tactccattg atgctttctg tcgttgcatt
    62221 gtcaatttca aggtcgtttt tattggcata cttgctgagc atctcttcca ctgtagtagc
    62281 aacgataaca ttttggtact cgactgcgtc taccagggcg tactctttga ccaagccagc
    62341 attgtccttc aagcccatga tgtagagagg cttgtcattg aggttgatga ggattgggaa
    62401 ggttgctttg taggatttct cctgaacagc accttctgct gattcacggg ctgattcttc
    62461 tgtcgcagaa gccaagctat acttagtgat ttctcctgtt cgcatatttt caaggatgaa
    62521 accaagatta ctctcatccg cattagccga cgtcacacct gtgtagagat agatgtcatt
    62581 accgatagac aagtaattat agcccttggt agtctgggtc acgtttttct tggaaatcat
    62641 ggcattcaag aaaccgtcct tgtacttgcc gttgtagttg atttgctcaa tggtttcctc
    62701 tgctggatag atcctgtcca cccattctgg aacatctgat aagctgtatt ccttggtttc
    62761 tccatttgta gcatccaaga taatgactga agcaggacga ggaacagcaa gtccaaattg
    62821 cttttggtaa accgttgcta catagaaagg attgccctca tcgtccacct caaaagatgg
    62881 agttttaaag attttggtcg ggtacttcaa gcgcaggtga cgtttgacat cacggttaaa
    62941 atactccgag tctgaatact tgattggtgt cttcaagtcc accaaatccg catttccagt
    63001 taccatgtcc accttgatat actcaccgat tcccttggct tgattgttaa accatttgat
    63061 agggtctgca tattctagtg gtgtgacccg ataaggtttc ccatcaattg tcaattgggt
    63121 ataggtatct gccgctacgt attgcgacac cttatcggtt agggaaccca agtagcggtc
    63181 tccaattttt tcagcagtac ttctatctag gataggaacc ttactggtgt cactcttagg
    63241 aaattcagta aagtcttttt ccgtaaccgt gactacattg gcataatttt tagcctgaaa
    63301 catgctggaa gttaccaagg aaaccaaagc tgccaagaga agaattcctc caatcgaagc
    63361 taacagaatt ttccctaacc gattgatttt gaaaccctca agatttaagg cagcttccgc
    63421 cttaccgtgg cgcacatgaa ccgttttgac aaggtttatc cccttgccaa agccaaataa
    63481 gattgccaca actaacaaat gcccacagag gaagaagaga aattcccagc tggtcaggtt
    63541 aaggggcggt aaaaagatat accaggtcgt tgcgataaaa ataagttcaa agactattcg
    63601 tttcatttgc tttcctccta aatgattcgt ccttccaagt gatccagctc atgctggcaa
    63661 atctgagctg ggaagcctgt caaggtaatg gtctgttcct gccacttgct gtcacgatag
    63721 gcaaccctta tggtttcata acgcttagtt gatctcacac ctaccaagga caaacagcct
    63781 tcttctgcct cataggatcc ttcaaaggac agaagcactg ggttaaacat gaccacggga
    63841 accaagccaa gattaaagat aatcacgcgc ttctgcaccc caatcatatt ggcagctaga
    63901 ccaacacagg tatcacgatt tgctaagagt gtatcctgca aatctctggc aagataaagg
    63961 tcctcctgac ttgccggctg agacacttga gataaaaata agatatcctt cacaattttc
    64021 ttttccactt cctcacactc ctcttgcttt ttactatatt atagcaatta tagcacaaaa
    64081 gccgataact gcaaaccctt tccctcaact gtagcaaaaa gccatccgaa gatgactttt
    64141 ttgctattta atttctgtat aagttacttc caagccacgc ttaacagctg gacgattggc
    64201 aattttttct gcccatttta ctagattttg ataacttgag gcatccaaga attttgcaga
    64261 accttggtaa agatttcctt gaactaactg tccataccaa gaccagatag caatatctgc
    64321 aatcgtatag tcattgcctg caatataagg tttctgagcc aattccttat ccaataaatc
    64381 caactggcgt ttcacttcca tcgtaaaacg gttaatagga tattccaatt tttcaggagc
    64441 ataattgaag aaatgtccaa atcccccacc tagaaaaggt gctgcacctg cttgccagaa
    64501 tagccaattc aaaacttcta ccttttccac aggattactt ggtaaaaagg ctccaaattt
    64561 ctcagcaagg taaagaagaa tatgagcaga ctcaaagact cttacgtttt cagtacctga
    64621 ctggtccaat aaggctggaa tcttggaatt tggattgagc ttcacaaagt ctgagccgaa
    64681 ttgatcccca tccatgatag caatcttata caagtcgtaa gccgcttcct taaaaccagc
    64741 ttctagtaat tcttccaata agatagtaac cttcacacca tttggtgttc ccagtgaata
    64801 aagctgaaaa gcttgttctc cttttggcaa gttttgttcg aaacgggcac ctgctgttgg
    64861 tctgtttagc cccgtaaaag ctccttgatt actagcttca tcctgccata cggtcggtaa
    64921 ttgatatgct gacatccgaa acctccctta aatcgcattc ttgtcaaaac cgagtttgcg
    64981 ttgaataaac ttaacgattt cgacgatgat aatcattgag aagcttccag ccataacaat
    65041 tccccattgt gacaagtcta gtttggttac gtggaagatt ccttcaagcg gttctacaac
    65101 gattgttgcc atgagaagga taaaggatac caagatggac cagttaaagg tcttagactt
    65161 gaatgggcca actgtcaaga tggattggta gacagacttg acattgtagg catggaagag
    65221 ctgaatcaaa ccaagggttg caaaggccat cgttagggca tctgcatgaa tagcatgatt
    65281 gtcacccaca tgaactgggt aagcaatcgc aaggccataa acactcataa caagagctgc
    65341 ttggagtaca ccttgataaa tgatagaact caaaacacca cctgagaaga agcttgcctt
    65401 gcgtccacgt ggtttatgat tcatgacacc aggttccgca ggttcaacac ctagtgcaat
    65461 tgctgggaag gtatccgtta ccaagttaat ccacaaaaga tgaactggct gcaagacgtc
    65521 ccaaccaaac aaggttgata ggaagatggt taatacttca gcagtattgg cagaaagtag
    65581 gtactgaata gtcttttgaa tatttgagaa gaccttacgt ccttcttcca ctgcgacgat
    65641 aatagtcgca aagttatcat ctgcaagaat catatcagaa gcccccttag aaacctctgt
    65701 accagtgatt cccataccga taccgatgtc tgctgttttc agagctgggg catcattgac
    65761 accgtcacct gtcatggcaa cgaccttacc ttgtttttgc caagccttga cgatacgaac
    65821 cttgtgctct ggagacacac gggcataaac agagtattga ccaacaactt tttcaaagtc
    65881 ttcatcagat aattcgttga gctcagcacc agttaaaacg tggtcttctg tatcgtttgc
    65941 gtcaatgatt cccaaacgtt tggcaatagc ttctgcggtg tcttggtggt cacctgtaat
    66001 cataattgga cgaattccag cttccttagc cacacgaaca gcctcagcag cttcaggacg
    66061 ttcaggatca atcatcccaa tcaaaccagt aaaaattaaa tcattttcaa gctcttcaga
    66121 agtgagattt tctggaatac tatcgataat cttataagca cctgcaagga cacgcaaggc
    66181 ttgatgagcc atttcagaat tgtttgtatg aatgagattt gtaaccttct catcaatcgg
    66241 agcaatatcc ccagccttat cacgaagaag acaacgtttt aagagttggt ctggcgcacc
    66301 cttgactgct acaaggaaac gaccatctgg caatgggtga actgttgaca tgagcttacg
    66361 gtcagagtca aatggcaatt cagctacacg aggatatttc tctaagaaac ctttgacatc
    66421 atagcccttg tccaaggcat attggataaa ggctgtttcg gttgggtcac caatcaagtt
    66481 accttccaca tcgattttcg tatcattggc caagacaact gaacgaagta gtggcatttc
    66541 aagacctagt tcaatatcat cagctgagtc atgtagaacc gcatcgtaga agactttttc
    66601 gactgtcatc ttgttcatag tcagcgtacc agtcttatca gaagcgatga tttcagttga
    66661 accaagtgtt tcaactgctg gcaacttacg aacgatggaa tgtcgtttgg ccaaaacttg
    66721 agtaccaaga gaaagaacga tggtaacgat agcaggaagt ccttctggaa tggctgcaac
    66781 agcaagggca acagaagtca acaactcacc aagtggattt ttcccttgaa tgaagacacc
    66841 cactacaaaa gtaacaaggg caatgaccaa gatagcatag gtcaagacct tagaaaggtt
    66901 gttcaagttt tgtttgagtg gtgtatcagt ctcatccgca tcttgaagca taccagcaat
    66961 atgaccaact tcagtgtaca tacctgtatt gacaacaaca cccatcccac gaccataggt
    67021 tacgtttgag ttttggaagg ccatgttgac acggtcacca ataccagcat ctgtcgcaag
    67081 ctcgactgac aagtcttttt cgactggtac agattcaccc gtcaaggctg cttcttcaat
    67141 tttaagagag ttggcttcta gcaaacgtag gtccgctggt accacgtcac ctgcttcaag
    67201 ggcaacgata tcgcctggta ccaattcttt agagtcaatc tctgccatgt gtccatcacg
    67261 aagaacgcgg gcaactggac tagacatgga tttgagggct tcaatagctt cttcagcttt
    67321 tccttcttgg taaacaccaa aggcagcgtt gatgataacc acagctagga tgataatggc
    67381 atctgcgata tcttccccac cagaagtcac gactgacaag attgctgccg caactaggat
    67441 gataatcatc aaatccttaa attgctcgat gaatttgacc aagattgatc gtttctcgcc
    67501 ttcttcgagt tcattgtgcc caaattcggc aaggcgcttt tccgcctcac ttgatgacaa
    67561 accttgctcg gtcgcatcca cagcctgcaa gacctcttca gggctctgag tataaaacgc
    67621 ttggcgtttt tgttcttttg acatgtgtct cctccttgac attgtgtgca aaacagactc
    67681 tctttctgtc atatcttttc acgacaaaca aaaagagacc tgttaatcat aacaagtctc
    67741 gctgtttaag atagggccgg aaagcatact tttcagcata aaattcggaa tgacgacact
    67801 atcacaggtt tctgccagct actcccttga gtagtaccat tataccaaat tttggggagt
    67861 tttcaaagag taaaaactgc cttatttgaa tttttccttg aaaaccagta taatggtaga
    67921 atgctatgtg actagaaagg aagttgaatg aagcaatcta tctcaaatct caagttagct
    67981 gagcgtggag ccattatcag tatttcgacc tatttgatct tgtctgcagc caaattagca
    68041 gctggtcatc tccttcattc atccagtttg gtggccgatg gttttaataa cgtatcggac
    68101 atcattggaa atgtggccct cttaatcggg attcggatgg cgcgccagcc tgcagaccgt
    68161 gaccaccgtt ttggtcattg gaagattgaa gatttggcaa gcttgatcac ttctatcatc
    68221 atgttctatg tcggtttcga tgttctaaga gataccattc aaaagattct cagtcgggaa
    68281 gaaacggtca ttgatcctct tggtgcaact ctaggaatca tttctgcagc gattatgttt
    68341 gtggtctatc tctacaatac tcgcctcagt aagaaatcca actccaaggc gctgaaggca
    68401 gctgctaagg acaatctttc tgacgctgtt acctcacttg gaaccgccat tgccatccta
    68461 gctagtagtt tcaattatcc gattgtggat aaactggttg ctatcatcat cactttcttt
    68521 atcttgaaga ctgcctatga tatcttcatc gagtcttcct ttagtctttc agatggcttt
    68581 gacgaccgcc tgctcgagga ctaccaaaag gctatcatgg aaattcccaa aatcagcaag
    68641 gtcaaatcgc aaagaggtcg cacctacggt agcaacatct acctggatat tacactagag
    68701 atgaatcctg acttgtctgt ttttgaaagc catgaaatcg cggatcaggt cgagtctatg
    68761 ctggaggagc gttttggcgt ctttgatacc gatgtccata tcgaaccagc acctatccct
    68821 gaggatgaaa ttttagacaa tgtctataaa aaattgctta tgcgtgaaca attgatcgac
    68881 caaggaaacc aactagaaga actcttgact gatgattttg tctatattcg ccaagatgga
    68941 gagcagatgg ataaagaggc ttataagacc aaaaaagagt taaattctgc tatcaaggac
    69001 attcaaatta cttccatcag tcaaaaaacc aaacttatct gctatgagtt agatggtatc
    69061 atccatacca gtatctggcg tcgccacgaa acctggcaaa atatctttca tcaagaaacc
    69121 aaaaaagaat agagaaatcc tttcatgaga cgggattttt ctattctttt atactcaata
    69181 aaaatcaaag tgcaaattag gaagccggtc acaggctgta cttgagtcgg caatgtgaag
    69241 ccgacatagt ttgcactttg attttcgaat agtcttaact atcaaattca ctgagatact
    69301 catagcgttc gtatttttca aggagtgctt catttttctc atccaattct ttttggagag
    69361 tagccagctt accaaagtca gagccgttag cctgcatttc ctcttcaata gcagcgatac
    69421 gtttttccaa ggtttcaata tcaccttcaa tacttgccca ctcctgcttt tcttggtagg
    69481 tcatgcgttt cttgtcttct cgaaccttga ccactttttc cttttcggcc ttttgcactt
    69541 gattggccat atctgtttca aaagcttttt catcaagata gtcggtgtaa tgaccaaaga
    69601 aaggacgaat cttgccatcc tcaaaagcga gaatcttggt cgctacctta tccaagaaat
    69661 agcggtcgtg actgactgtt aaaacgggac ctgcaaaacc ttgcaagaaa ttctccaaga
    69721 ctgtcaaagt tgcaatatct aggtcattgg ttggctcgtc taaaagaaga acatttggtt
    69781 tttccaaaag cagtttgagg agataaagac gttttttctc accccctgac aatttctcaa
    69841 tcaaggttcc atgcgtcgaa cgtgggaaaa ggaactgctc cagcaactct gcaatcgaag
    69901 tcgtagaacc gccactggtc ttgacctctt ctgccacttc ctgcaggtaa ttgataactc
    69961 tcttgctttc atccaaaccc tcaatttgct gagagaaata ggcgatgcga acagtttccc
    70021 caatcacaac ttgtccttta gttggctcaa gacttcctgc aatcaagttg agcagggttg
    70081 attttccaac accattgtcc ccaacgattc cgatacggtc tttggcctgc accaagagat
    70141 taaaatcttg caaaataggc ttgttttcat aggcaaagga aacagcctga aactcgatga
    70201 ctttcttccc aatccgactg gtttcaaagt tcatggtcaa gtctgtctca gcactactgc
    70261 ctgaaacttc ctttttcaga tcatggaatc gattgatacg ggcctgctgc ttggtcgcac
    70321 gcgcctgcgg ttgtctgcgc atccaggcca attcttgttt gtagagttgt tcttttttgt
    70381 gaagaagagc cgcgtcgcgc tcatcctgtt ccgcctttag gcgaacatag tcctggtaat
    70441 ttccctggta ctcggtcaag cctgcacgat ccaactcgaa aatccgtgtt gacaaagcgt
    70501 ctaagaaata acgatcgtga gtgataaaaa ggacggtctt cttagaattt ttcaaaaaga
    70561 gggtcagcca ctcaataatc gcaatatcca gatggttggt cggctcatcc aaaagcaaga
    70621 gatcgtggtt gccaagtaag acttgtgcca actgtacccg tcttctcaga ccacctgaca
    70681 attccccaac aggagtagat aagtcttgaa tgcccaattt gctaagaacg gtcttgacct
    70741 gactttcgat ttcccaagct tggagagagt ccatctctgc catgacacgt tccaaacgcg
    70801 cctgcttgtc ctcactatag tcgagcataa tcaattcata ctcacgaatg agctggattt
    70861 ccttgagttc actagataga accgtatcca aaactgtctt tctatcatca aaatcaggat
    70921 cctgagtcaa gtaaccaatc tggtaatcat ttttagctga aaaaggactg acatccccat
    70981 caaatccaga aacaccagaa aggacgtcca aaagggtggt cttgccagtc ccattgacac
    71041 cgattaaacc aattctgtct aagtcatgga taataaagga aatatcccta aaaacggtct
    71101 tgtcaccaac ggatttactt agtttttcaa cgataaaatc actcattttt tctccctcag
    71161 gtaagcatgg atggcttcac gattattctc caattctcca tcgacaatgg caaactcaat
    71221 ctctgttaaa atctctccca agtctgggcc tggctgatag ccatattcct tgatcaaaat
    71281 accgccatta atctgaatat ctttcttgtc atggatagtc aagctttggt atttttctgt
    71341 gatggcttgt gggttgactt cttttccttg agcttgacga agattttcag cctgtaaaag
    71401 caaatctatg tcaaagcgat aacaatctcg cttgctcaat tctccatttt cacgcagagc
    71461 caaaataatc agcaaatcct gaacttgctt ggcaaactgg cgtgaggtct tccaagattt
    71521 caaaaatgac tgcgcatttt caatctccaa agcccatagt aaagccgccc aggcttgttc
    71581 agaggattca aaagtaaaat cagtctccaa atcaaacagt ctgttgagct tgtcctggct
    71641 agatgccata tcagggagat agtcataagc ttgactctca atcatggaag ccaagcccct
    71701 tctccaaaat ggagccagca agagtttatc aaactcgacg aaggtacgct ctacagaaat
    71761 tttctccaaa agcggcgtca aggtcttcat agctttaaat gtttctggct caagtgcaaa
    71821 accaagacta gcctgaaaac ggaaaccacg cataatccgt aaagcatctt cgttgaaacg
    71881 ctcactagcc actccaactg ctcgcaagac ttgcttttcc aaatcttcta aaccatggaa
    71941 caagtcaacg atttctcctg tctcatccaa ggcaaaggcg ttgactgtga aatcacggcg
    72001 tttgaggtct tcttctagcg agcgcacaaa ggaaaccgca ctgggtctgc gatagtccac
    72061 atagacatcc tctgtccgaa aggttgttac ctcatactcc tcatccccat ctaagaccaa
    72121 gacggttcca tgctcgattc cgatatcggc tgttcgcgga aaaatctgct tggtctcttc
    72181 tggataagaa gacgtcgcaa tatccacatc gtggataggg ctatggagaa gggcatctcg
    72241 aacagagccc ccaacaaaat aagcctcaaa gcctgcttct ttaatttttt ctaatactgg
    72301 taaagccttc tgaaattcag aaggcatttg cattaatctc ataataagtg ttctaatcca
    72361 tagacaagct catgacgctt gacaacttct ttaattccca aattgactcc tgtcatgaag
    72421 gagatgcgat cataggagtc atgacggagg gtcaatcctt ctccttgatt gccaaagatg
    72481 acttcctgat gggctaccaa acctggcaaa cgaactgagt ggatgcgcat accatcaaag
    72541 tcagcaccac gagcaccagt aatcagctct tcctcatctg ctgcaccttg ctgaattgac
    72601 tctcgaatct ctgccatcaa ctcagctgtt ttaatggctg ttccactcgg agcatccttt
    72661 ttcttgtcat gatggagctc aataatctcc acatttggga aatatttggc agcctgcgtc
    72721 gcaaattgca tgagtaagac agcacccaag gcaaagttag gggcaatcag gccacccaag
    72781 tcttgggtac gagaaaattc ttttagctct gcaatttctt cactcgtgaa accagtcgtt
    72841 ccaactactg gagcaaagcc attttcaaga gcaaaacgtg tattttcgta ggcaacagct
    72901 ggagtagtaa aatctaccca gacatccgct tcaaaacaag ctaaatcagc cttatccttg
    72961 aaaacaggaa taccctgcca ttctgactca gactcaaaag gatccaaaac tgctaccaag
    73021 tccaagtctg gatcagtcaa taccatctga caagcagcct ggcccatctt tcccttaaaa
    73081 ccggcaataa ttactcgaat actcatctct actcctgtct aagatacaaa gtccgtaaga
    73141 acacaaagtg aaaataggaa ttccaatcaa gaagtgtcta cttcttggaa gaactatctt
    73201 tttcacacag ggttccaggc gtgttcaatt atcaagatac aaaggacctt agctgcctct
    73261 gaaaaatagg gaatggcact gactttccac gaaaggcaag acaggcatct tttttcaaga
    73321 ggcaggtagt ccgtgttcaa tttctaagat acaaggcatc ttaactagcc tagaagcgcc
    73381 aactaaatca ctggaatata acccagagca atacttcctg ctcctaggtg cgttccaatg
    73441 acactaccaa atgtagcaag tgaaacatcc gaacccaagc caaaatcaag caagtgctga
    73501 cgcaattctt cagccttttc aggagcattc ccatgaatga caatgacccg gtattgacct
    73561 gaagccgttg tttccttgat aatttcaatt aagcgcttgg tggccttctt ttcagtacga
    73621 actttttcgt aaacttcaat cacaccttga tcgttaaaat aaaggattgg cttaatgcta
    73681 agcaaattgc ccaaaatggc agccccattt gaaaggcgtc caccttttac caaatgatcc
    73741 aagtcatcta ccatgataaa ggctgacgta cggctgattt gaatggctag cttatcctga
    73801 atgctggcaa aatcatcgcc ctgatcacgc caattaaaga cgctttcaac catgatgcct
    73861 aggggagcac ttgtaatcaa agtgtctggg aaagcaatgg ttaagccctc atagtcatcg
    73921 accatatact ggatattttg gtaaaaacct gaaattccag aagataggaa aagccccaag
    73981 gcatgtgtat agccttgttc tttgagcgaa gttaagatct catctaactt ggcaatactt
    74041 ggttgactgg tcttaggcaa ttcagaagcc tgagccattt tttggtaaaa ttcctcagca
    74101 gacagattga tgccttcgac atattcctca ccatcaatat tgacaggaat atccaagaca
    74161 aacaagtctt ctctttgcaa ggtctcttca ctgagataag cagaggaatc tgtgaaaaca
    74221 gctaatttca tattagaact ccaaattaat tcctggtaag tctaatgcaa tttcagtcac
    74281 ttcgtaagtc aaacgattga gcatgttcaa acatggacga gccaaggttt ccacctcttc
    74341 ttggttcaat tcacttggtt cattgacaat acggccatcg atatggttta cttgtgagat
    74401 tgttccacta atgacaaact tatcaaatac aatcataaag ctcaagatga caatcaagga
    74461 agtcacttga ttttcttggt catgttggag caattggaaa ttcacatcca ccttggtttc
    74521 aggagctcca ttttcatttt cccattcaaa attacgcgca tcaaaatgat actgactaac
    74581 aaattcttgt tcacgtttaa gattcatgtc tttctccatc ggctacaata ttataagcta
    74641 ttgtaccata attttttatt ttcatctagt tttctaggat ttagtcaatc ccaatttcag
    74701 cacgaactac atctgtgata gtatcaacat agtagtccac ttcttctgtt gtaggcgctt
    74761 ctgccataac acgcaagagg ggctctgttc cacttggacg aacaaggata cggccgttcc
    74821 ccgccatttc ttcttccatc ttctcgatga tggccttgat agctggcact tccatggcct
    74881 tttccttcat gacgttttcc actcggatat taactaattt ttgtggataa atcgttactt
    74941 ctgccgccaa ctctgataag cttttaccag ttttcttcat aattttagtc aattgaactg
    75001 ctgataattg accatcacct gtggtattgt aatccatcaa gataacgtga ccagactgtt
    75061 caccaccaag gttgtagcct gattttctca tttcttcaac aacgtagcgg tcaccaactg
    75121 cagtaactgc cttgttaata ccttcgcgat tcaaggcctt gtggaaacca aggttagaca
    75181 taacagttgt cacaattgta ttttgagcca attgtccttt ttcagaaagg tattttccga
    75241 tgatgtacat aatcttgtca ccatcgacga tgtcaccatt ctcatcaaca gcaatcaagc
    75301 ggtcactgtc tccatcaaag gccaaaccaa tagctgaccc actttctttg accacttctt
    75361 gaagggcttc tggatgtgtt gaaccaacat taaggttgat gttaagaccg tctggtgttt
    75421 ccccgataac cgtcaattgg gcaccaaggt ctgcaaagat ttgacgggca ctggtagaag
    75481 ctgctccatt agctgtatcc aaggcaacct tcattccatc aagaggagtt ccagttgaaa
    75541 caaggtatcc ttcatactta cgcaagcctt ctggataatc taccaaaatt cctaagcctt
    75601 ctgcacttgg acgaggaaga gtgtcttcct cagcatctag caaggcttca atttctgctt
    75661 ctttttcatc atctagtttg aagccatcac cgccaaagaa cttgattccg ttatcaaggg
    75721 ctgggttgtg gctagcagaa atcatgacac cggcacttgc tccttcagtt tcaaccaagt
    75781 aagctactgc tggtgttgca aggacaccaa gtttgtatac gtgaatccct actgaaagga
    75841 gacctgccac caaggccgat tccagcattt cccctgaaat acgtgtgtca cgtcctacaa
    75901 agactttcgg cgcttccgtt tcatgttgac taagaacata gcctccaaaa cgtcctagtt
    75961 taaaggctaa ttctggtgtt agttctaggt tagcttctcc acggactcca tcagtcccaa
    76021 aatatttacc cattgttata aaatcctttt ctatttttaa ttcgtttttg aactagttgc
    76081 tttcgttgac gaagatgtct ccgatgaact gcttgtactt gaatttgatg tgcttgaact
    76141 tggtgctact ggttttgtag tcaccttcat tattgtatca aacggagtga taactgccgg
    76201 taagacaaca ccattgcggt cgattgcctg caaaggtact gaaccactgt aattacctgt
    76261 tatacgttcg ctagttggca agacagcgat aatcttatca attctatcca atgtctcttg
    76321 gtcactcgta atcgacactt ctttatctga caccatgaca ttttcaattt gtacccgact
    76381 atcaatttga ctagggtcaa tctctggtac aatctttacc ttatccttct gagccttctt
    76441 accaatcttg actgtaattt tttgcggagt cgccacagcg gtcagcccat tgggtaaatc
    76501 ttcaatgctc aaaggaactt caatcgttcc aacaccggca tctgttaggt cagcagtaac
    76561 cttgaattta cgtgtacttt cttgcatttc actagctagc gataggcgat ttgcaccagt
    76621 caagaccact gatacttctg aagcaaaacc gctaataaaa tacttatcac tattatagcg
    76681 tatgtcaata gggacatttg ttactgtatt agtataggtt tccgttttta cctgcctagc
    76741 actggtactg ttttgaaaat tcgtcgccgt agcatagaca aataagacac aagcaaaaaa
    76801 gagtgaggat atgatatata aactattttt tttcatgttt ccatcctcct agccatcgtt
    76861 ctttaaaact aagacccact tcctcttttg gaagtaagat ttcacgtaat tctgtttcaa
    76921 attcatcaag tgttaggttg tgcttaaacc ttccattata ggttatcgaa attcctcccg
    76981 tttcctctga tacgacaaaa gtcaaggcat ctgagacttc tgataaaccg atagccgccc
    77041 ggtgtctggt cccaaattcc ttggaaatac ctgtgttttt tgtcaagggc agataggcag
    77101 acgtcacagc gatacgttct tctttgataa tcaccgcacc gtcatgtagg ggagtgttgg
    77161 gaataaaaat gttaatgaga agttctgcag aaatcttagc atccaagggg attcctgtcg
    77221 aaatatactc ctgcaaggta cgtacacgct gaatagcaac caaggccccg attttacgag
    77281 gactcatgta ttcaacagac ttaacaaagg cacgaatcat ctgttcctca gcactaatag
    77341 gggcattgga aaagaaatct gtcgctcttc ccaaacgttc caaaccagtc cgaatctctg
    77401 gagagaagat aacaaccgcc gcaataaccc cataagtaat aatttgattg attaaccaag
    77461 aaatcgtagt caaaccaatc atatttgcaa ggatttgagc taaaataaat accaaaactc
    77521 cacgtaccaa aatcataatc ttggttcctg caatagcttt tgtaaaatgg tataaaatat
    77581 aagcaacaat caaaatatca atcagattga tagctatcgt ccatggactt gcaaacaaac
    77641 tggtccaata ttgcagattg gataattgtt gaaaattcat ccctgatatc ctccctatca
    77701 aaacactttc gtcctattat accattttcg ggcatttttt tccctatcct agtccatttt
    77761 acattgaaca aaaatatgat aaaataaact gactagaaaa aacaaaggag aaactatgtc
    77821 tcaactctat gatattacca ttgtgggtgg tggtcctgtc gggctttttg cagcctttta
    77881 tgcccaccta cgccaagcca aggttcaaat catcgactct cttccccagc taggtggaca
    77941 acctgctatt ctctaccctg aaaaggaaat cctagacgta ccaggcttcc caaacctgac
    78001 tggagaagag ttgactaacc gcttgattga acagctaaat ggatttgata cccctattca
    78061 tctcaatgaa acggttcttg agattgacaa acaagaagaa gaatttgcca tcacaacttc
    78121 taaaggaagt cacctgacta aaacagttat catcgctatg ggtggcggtg ccttcaaacc
    78181 acgtccgctg gaacttgaag gggttgaggg ctatgaaaat atccactacc acgtttctaa
    78241 cattcagcaa tacgctggta agaaagtgac gattcttggt gggggagact cggctgtgga
    78301 ttgggctttg gcttttgaaa aaatcgcacc aactaccctt gttcaccgca gagataattt
    78361 ccgtgccttg gaacacagtg ttcaagcctt gcaagaatca tctgtaacca tcaagacacc
    78421 attcgcccct ggccaactcc ttggaaatgg aaaaacactt gataaacttg aaatcacaaa
    78481 agtcaaatct gatgaaactg aaaccattga cctagaccac ctctttgtca actatggttt
    78541 caaatcttct gtcggtaacc ttaaaaactg ggggctcgac ctcaaccgtc acaagattat
    78601 cgtcaacagc aaacaagaat ccagccaagc aggtatctat gctatcggtg actgctgcta
    78661 ctatgacgga aaaattgatc tgattgcgac aggcctcgga gaagctccaa ctgctgtcaa
    78721 caacgctatc aactacattg accctgaaca aaaagtacaa ccaaaacact ctaccagttt
    78781 ataaaaaaga accacgagtc acataggatt cgtggtttta taattcatcc gcatttaaaa
    78841 atacctttac atcgttttac tatatcttac aatacctttt aaaacagcta tattttgagc
    78901 ttttaaataa atgtttttac atcattttac agagatttac gacacttttg cccctttttt
    78961 gccccttttg agcaaacaaa aaaaccgcaa gcctgagcct gcggtgaaag aacaatttag
    79021 aaagtttcct ttctatttat ttaactgtaa tcaagccatc tggctctact gtgaactctg
    79081 gcttgtctgc cagtgttccg tctggtttga ggtagtacca gcctgttccg tccgctgact
    79141 ggataaaggc atttgatacc atggcgcctt ctttagcgtc taagtagtac caagtgtcct
    79201 tgtacttgac ccagcctgtc ttcatggcac cttctacatc aaaatagtac cacttgtcag
    79261 cgattttctg ccagcctgtg gccatttcgc ctgattggtc aaagtagtac caattaccgt
    79321 ctgtgtgctt cttccagcgg tctg
//
LOCUS       DAVLGK010000003        73444 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLGK010000003 DAVLGK010000000
VERSION     DAVLGK010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 73444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73444
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.003"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            167..823
                     /locus_tag="VXE01_000211"
     CDS             167..823
                     /locus_tag="VXE01_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV0749203.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            813..1022
                     /locus_tag="VXE01_000212"
     CDS             813..1022
                     /locus_tag="VXE01_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV0749204.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIK"
     gene            1240..2070
                     /locus_tag="VXE01_000213"
     CDS             1240..2070
                     /locus_tag="VXE01_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0749205.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2224..3078
                     /locus_tag="VXE01_000214"
     CDS             2224..3078
                     /locus_tag="VXE01_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0749206.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3178..4551
                     /locus_tag="VXE01_000215"
     CDS             3178..4551
                     /locus_tag="VXE01_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV0749207.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4544..5605
                     /locus_tag="VXE01_000216"
     CDS             4544..5605
                     /locus_tag="VXE01_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV0749208.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5607..6299
                     /locus_tag="VXE01_000217"
     CDS             5607..6299
                     /locus_tag="VXE01_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0749209.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6329..6898)
                     /locus_tag="VXE01_000218"
     CDS             complement(6329..6898)
                     /locus_tag="VXE01_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0749210.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7033..7647
                     /locus_tag="VXE01_000219"
     CDS             7033..7647
                     /locus_tag="VXE01_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0749211.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7649..9295
                     /locus_tag="VXE01_000220"
     CDS             7649..9295
                     /locus_tag="VXE01_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0749212.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHMGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9307..10593
                     /locus_tag="VXE01_000221"
     CDS             9307..10593
                     /locus_tag="VXE01_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0749213.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10645..11178
                     /locus_tag="VXE01_000222"
     CDS             10645..11178
                     /locus_tag="VXE01_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0749214.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11256..11726
                     /gene="nrdI"
                     /locus_tag="VXE01_000223"
     CDS             11256..11726
                     /gene="nrdI"
                     /locus_tag="VXE01_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV0749215.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12019..13281)
                     /locus_tag="VXE01_000224"
     CDS             complement(12019..13281)
                     /locus_tag="VXE01_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV0749216.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13591..14049)
                     /locus_tag="VXE01_000225"
     CDS             complement(13591..14049)
                     /locus_tag="VXE01_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV0749217.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14046..14486)
                     /locus_tag="VXE01_000226"
     CDS             complement(14046..14486)
                     /locus_tag="VXE01_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0749218.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14842..16791
                     /gene="mutL"
                     /locus_tag="VXE01_000227"
     CDS             14842..16791
                     /gene="mutL"
                     /locus_tag="VXE01_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV0749219.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMALVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17117..17584)
                     /locus_tag="VXE01_000228"
     CDS             complement(17117..17584)
                     /locus_tag="VXE01_000228"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV0749220.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17585..18790)
                     /locus_tag="VXE01_000229"
     CDS             complement(17585..18790)
                     /locus_tag="VXE01_000229"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV0749221.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDILGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYNSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18810..19445)
                     /gene="ribE"
                     /locus_tag="VXE01_000230"
     CDS             complement(18810..19445)
                     /gene="ribE"
                     /locus_tag="VXE01_000230"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV0749222.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19430..20530)
                     /gene="ribD"
                     /locus_tag="VXE01_000231"
     CDS             complement(19430..20530)
                     /gene="ribD"
                     /locus_tag="VXE01_000231"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV0749223.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYTFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20664..20778)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            20935..21528
                     /gene="ruvA"
                     /locus_tag="VXE01_000232"
     CDS             20935..21528
                     /gene="ruvA"
                     /locus_tag="VXE01_000232"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV0749224.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21538..22101
                     /locus_tag="VXE01_000233"
     CDS             21538..22101
                     /locus_tag="VXE01_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV0749225.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLYDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22098..22775
                     /locus_tag="VXE01_000234"
     CDS             22098..22775
                     /locus_tag="VXE01_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0749226.1"
                     /translation="MMSNKNKGILIFAILYTILFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(22912..23943)
                     /locus_tag="VXE01_000235"
     CDS             complement(22912..23943)
                     /locus_tag="VXE01_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV0749227.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDAYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(24198..24881)
                     /locus_tag="VXE01_000236"
     CDS             complement(24198..24881)
                     /locus_tag="VXE01_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV0749228.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDIDCSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24893..25837)
                     /locus_tag="VXE01_000237"
     CDS             complement(24893..25837)
                     /locus_tag="VXE01_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0749229.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            25969..28800
                     /gene="uvrA"
                     /locus_tag="VXE01_000238"
     CDS             25969..28800
                     /gene="uvrA"
                     /locus_tag="VXE01_000238"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV0749230.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVVEKIQKDGYVRVRVDGEVYDVTEVPDLSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDSSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMTAFGVEMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVVNNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCHGYRLNDQALSVRVGGENGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28793..29854
                     /locus_tag="VXE01_000239"
     CDS             28793..29854
                     /locus_tag="VXE01_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0749231.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            29986..30384
                     /gene="spx"
                     /locus_tag="VXE01_000240"
     CDS             29986..30384
                     /gene="spx"
                     /locus_tag="VXE01_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV0749232.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30450..31019
                     /locus_tag="VXE01_000241"
     CDS             30450..31019
                     /locus_tag="VXE01_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0749233.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            31106..31372
                     /locus_tag="VXE01_000242"
     CDS             31106..31372
                     /locus_tag="VXE01_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV0749234.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31376..31795
                     /gene="ruvX"
                     /locus_tag="VXE01_000243"
     CDS             31376..31795
                     /gene="ruvX"
                     /locus_tag="VXE01_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV0749235.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31811..32116
                     /locus_tag="VXE01_000244"
     CDS             31811..32116
                     /locus_tag="VXE01_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV0749236.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32422..33672
                     /locus_tag="VXE01_000245"
     CDS             32422..33672
                     /locus_tag="VXE01_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0749237.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGDLAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33669..34214
                     /locus_tag="VXE01_000246"
     CDS             33669..34214
                     /locus_tag="VXE01_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV0749238.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDID
                     GTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVN
                     GNQIVVDDMDRDPSDQIVLTK"
     gene            34360..35892
                     /gene="cls"
                     /locus_tag="VXE01_000247"
     CDS             34360..35892
                     /gene="cls"
                     /locus_tag="VXE01_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV0749239.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            35970..36113
                     /locus_tag="VXE01_000248"
     CDS             35970..36113
                     /locus_tag="VXE01_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749240.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            36150..37688
                     /locus_tag="VXE01_000249"
     CDS             36150..37688
                     /locus_tag="VXE01_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0749241.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37808..40015
                     /gene="nrdD"
                     /locus_tag="VXE01_000250"
     CDS             37808..40015
                     /gene="nrdD"
                     /locus_tag="VXE01_000250"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV0749242.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALRKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            40027..40167
                     /locus_tag="VXE01_000251"
     CDS             40027..40167
                     /locus_tag="VXE01_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749243.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40211..40717
                     /locus_tag="VXE01_000252"
     CDS             40211..40717
                     /locus_tag="VXE01_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0749244.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            40710..41300
                     /gene="nrdG"
                     /locus_tag="VXE01_000253"
     CDS             40710..41300
                     /gene="nrdG"
                     /locus_tag="VXE01_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV0749245.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41297..41914
                     /locus_tag="VXE01_000254"
     CDS             41297..41914
                     /locus_tag="VXE01_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV0749246.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42180..42488
                     /gene="rpsJ"
                     /locus_tag="VXE01_000255"
     CDS             42180..42488
                     /gene="rpsJ"
                     /locus_tag="VXE01_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV0749247.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42705..43331
                     /gene="rplC"
                     /locus_tag="VXE01_000256"
     CDS             42705..43331
                     /gene="rplC"
                     /locus_tag="VXE01_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV0749248.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43356..43979
                     /gene="rplD"
                     /locus_tag="VXE01_000257"
     CDS             43356..43979
                     /gene="rplD"
                     /locus_tag="VXE01_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV0749249.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            43979..44275
                     /locus_tag="VXE01_000258"
     CDS             43979..44275
                     /locus_tag="VXE01_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV0749250.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44293..45126
                     /gene="rplB"
                     /locus_tag="VXE01_000259"
     CDS             44293..45126
                     /gene="rplB"
                     /locus_tag="VXE01_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV0749251.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45230..45511
                     /gene="rpsS"
                     /locus_tag="VXE01_000260"
     CDS             45230..45511
                     /gene="rpsS"
                     /locus_tag="VXE01_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV0749252.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45523..45867
                     /gene="rplV"
                     /locus_tag="VXE01_000261"
     CDS             45523..45867
                     /gene="rplV"
                     /locus_tag="VXE01_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV0749253.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45880..46533
                     /gene="rpsC"
                     /locus_tag="VXE01_000262"
     CDS             45880..46533
                     /gene="rpsC"
                     /locus_tag="VXE01_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV0749254.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46537..46950
                     /gene="rplP"
                     /locus_tag="VXE01_000263"
     CDS             46537..46950
                     /gene="rplP"
                     /locus_tag="VXE01_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV0749255.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            46960..47166
                     /locus_tag="VXE01_000264"
     CDS             46960..47166
                     /locus_tag="VXE01_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV0749256.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47191..47451
                     /gene="rpsQ"
                     /locus_tag="VXE01_000265"
     CDS             47191..47451
                     /gene="rpsQ"
                     /locus_tag="VXE01_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV0749257.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47477..47845
                     /gene="rplN"
                     /locus_tag="VXE01_000266"
     CDS             47477..47845
                     /gene="rplN"
                     /locus_tag="VXE01_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV0749258.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            47923..48228
                     /gene="rplX"
                     /locus_tag="VXE01_000267"
     CDS             47923..48228
                     /gene="rplX"
                     /locus_tag="VXE01_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV0749259.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48252..48794
                     /gene="rplE"
                     /locus_tag="VXE01_000268"
     CDS             48252..48794
                     /gene="rplE"
                     /locus_tag="VXE01_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV0749260.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48812..49081
                     /gene="rpsN"
                     /locus_tag="VXE01_000269"
     CDS             48812..49081
                     /gene="rpsN"
                     /locus_tag="VXE01_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV0749261.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49366..49764
                     /gene="rpsH"
                     /locus_tag="VXE01_000270"
     CDS             49366..49764
                     /gene="rpsH"
                     /locus_tag="VXE01_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV0749262.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            49956..50492
                     /gene="rplF"
                     /locus_tag="VXE01_000271"
     CDS             49956..50492
                     /gene="rplF"
                     /locus_tag="VXE01_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV0749263.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50576..50932
                     /gene="rplR"
                     /locus_tag="VXE01_000272"
     CDS             50576..50932
                     /gene="rplR"
                     /locus_tag="VXE01_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV0749264.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            50950..51444
                     /gene="rpsE"
                     /locus_tag="VXE01_000273"
     CDS             50950..51444
                     /gene="rpsE"
                     /locus_tag="VXE01_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV0749265.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51416..51640
                     /gene="rpmD"
                     /locus_tag="VXE01_000274"
     CDS             51416..51640
                     /gene="rpmD"
                     /locus_tag="VXE01_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV0749266.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            51785..52225
                     /gene="rplO"
                     /locus_tag="VXE01_000275"
     CDS             51785..52225
                     /gene="rplO"
                     /locus_tag="VXE01_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV0749267.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52238..53548
                     /gene="secY"
                     /locus_tag="VXE01_000276"
     CDS             52238..53548
                     /gene="secY"
                     /locus_tag="VXE01_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV0749268.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53699..54337
                     /locus_tag="VXE01_000277"
     CDS             53699..54337
                     /locus_tag="VXE01_000277"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV0749269.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAQALDKTLA
                     ELGIELEGVINIEVNPNSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54454..54672
                     /gene="infA"
                     /locus_tag="VXE01_000278"
     CDS             54454..54672
                     /gene="infA"
                     /locus_tag="VXE01_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV0749270.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54697..54813
                     /gene="rpmJ"
                     /locus_tag="VXE01_000279"
     CDS             54697..54813
                     /gene="rpmJ"
                     /locus_tag="VXE01_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV0749271.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54831..55196
                     /gene="rpsM"
                     /locus_tag="VXE01_000280"
     CDS             54831..55196
                     /gene="rpsM"
                     /locus_tag="VXE01_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV0749272.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55214..55597
                     /gene="rpsK"
                     /locus_tag="VXE01_000281"
     CDS             55214..55597
                     /gene="rpsK"
                     /locus_tag="VXE01_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV0749273.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55640..56575
                     /locus_tag="VXE01_000282"
     CDS             55640..56575
                     /locus_tag="VXE01_000282"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV0749274.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56587..56973
                     /gene="rplQ"
                     /locus_tag="VXE01_000283"
     CDS             56587..56973
                     /gene="rplQ"
                     /locus_tag="VXE01_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV0749275.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57238..57504
                     /locus_tag="VXE01_000284"
     CDS             57238..57504
                     /locus_tag="VXE01_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV0749276.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAIVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57514..58851
                     /locus_tag="VXE01_000285"
     CDS             57514..58851
                     /locus_tag="VXE01_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV0749277.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMRVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59095..59787
                     /locus_tag="VXE01_000286"
     CDS             59095..59787
                     /locus_tag="VXE01_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0749278.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(59890..61525)
                     /locus_tag="VXE01_000287"
                     /pseudo
     CDS             complement(59890..61525)
                     /locus_tag="VXE01_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(61515..62138)
                     /locus_tag="VXE01_000288"
     CDS             complement(61515..62138)
                     /locus_tag="VXE01_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749279.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAI
                     SDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTIRDSVYLGLNTDYFIETGFASK
                     IQVSEESTFEEDLQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            complement(62124..62246)
                     /locus_tag="VXE01_000289"
                     /pseudo
     CDS             complement(62124..62246)
                     /locus_tag="VXE01_000289"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(62223..62593)
                     /locus_tag="VXE01_000290"
                     /pseudo
     CDS             complement(62223..62593)
                     /locus_tag="VXE01_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62606..63622)
                     /locus_tag="VXE01_000291"
     CDS             complement(62606..63622)
                     /locus_tag="VXE01_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0749280.1"
                     /translation="MKKKWMYYAACSSNESADDSSSDKGDGGSLVVYSPNSEGLIGAT
                     IPAFEEKYGIKVELIQAGTGELFKKLESEKEVPVADVIFGGSYTQYTTHGELFENYTS
                     KENDNVIKEYQNTTGYSTPYTLDGSVLIVNPDLTKGMNIEGYNDLFKPELKGKIATAD
                     PANSSSAFAQLTNMLQAQGGYKDDKAWSYVKDLFTLIDGKIGSSSSSVYKVVADGEMA
                     VGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQE
                     VQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDI
                     QSKQ"
     gene            complement(64209..64985)
                     /locus_tag="VXE01_000292"
     CDS             complement(64209..64985)
                     /locus_tag="VXE01_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV0749281.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            65107..65853
                     /locus_tag="VXE01_000293"
     CDS             65107..65853
                     /locus_tag="VXE01_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0749282.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            65866..66846
                     /locus_tag="VXE01_000294"
     CDS             65866..66846
                     /locus_tag="VXE01_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV0749283.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            67041..67361
                     /locus_tag="VXE01_000295"
     CDS             67041..67361
                     /locus_tag="VXE01_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0749284.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            67407..67715
                     /locus_tag="VXE01_000296"
     CDS             67407..67715
                     /locus_tag="VXE01_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0749285.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            67732..69030
                     /locus_tag="VXE01_000297"
     CDS             67732..69030
                     /locus_tag="VXE01_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0749286.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            69181..71619
                     /locus_tag="VXE01_000298"
     CDS             69181..71619
                     /locus_tag="VXE01_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV0749287.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            71638..72306
                     /locus_tag="VXE01_000299"
     CDS             71638..72306
                     /locus_tag="VXE01_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV0749288.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            72324..73412
                     /locus_tag="VXE01_000300"
     CDS             72324..73412
                     /locus_tag="VXE01_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV0749289.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT        22257 a        13335 c        16097 g        21755 t
ORIGIN      
        1 gtgttttgag ctgacttcat cagttctatc tgcaacctca aaacagtgtt ttgagcaacc
       61 tgcggctagt ttcctagttt gctctttgat tttcattgag tattattaag acaatatgag
      121 gagaaagatg aaagaaaaag gattttagga gggggcgcag gcagccatgc caacggctct
      181 tggctatgtc agtatcggcc tggcctgtgg gactatcggt gcgccctatg tgacacctgt
      241 tgagatgggc ttgatgagtc tctttgttta tgctgggagt gcccagtttg ccatgttggc
      301 actgattgtg gttcaagctc ctgtggcagc tattgctatg acggtttttc taatcaactt
      361 gcgtctcttt ttgttgagtt tacacgcatc gacttatttc cgtcatacca gtctttggta
      421 caatatcggt atgtctagta tcttgacaga tgagacctat ggcgttttga tgggtgaatt
      481 ggcccataca gacaaggtaa atcctatgtg gatgcacgga aacaatctta acagctatgt
      541 ggcttggttt gtggggacag tagtcggaac ggctctgggt ggcctgctac caaatccaga
      601 aatctttggc ttggattttg ccctggttgg gatgtttatt ggtatttttg cttcgcaatt
      661 tcagattatg caaagacgga ttcctgtccg caatctgctc attatcctag cagttgttgc
      721 ggtgtccttc tttttgctct tgacagtggt gtctcagtca ctagctgttc tgtttgcgac
      781 gctacttggt tgtagcatgg gggtggtttt agatggtcag taagtatctt ttattagcag
      841 ttattttctc tggcttggtg acttggattc tccgtatgat tcccttcatc ttagtcaagt
      901 ataagggctt gccggcaatc gttgagcgtt ttttgaagtt cttgcccgtt tccattatct
      961 ttgccctgat tctttcaagc gtagtgacag gtaaggttgg cagtcttcct caaatcaaat
     1021 gactggactt cttagccgtc tttccaacag cttgggtagc ctttcgctac cgcaatctag
     1081 tcggaacagt tctctttgga gtggtcttga ttgccatctt gcgtttggtc ttttaaatta
     1141 cccataaaaa aaacttatca cagagataga tatcatataa tggcgtaaat gctctttttc
     1201 tgttaagatt ataaggtatt ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac
     1261 tcatctcttg cagcccttgc tcttgttgct gcaggtgtgc ttgcggcttg ctcaggtggt
     1321 gctaagaaag aaggagaagc agctagcaag aaagaaatca tcgttgcaac caatggatca
     1381 ccaaagccat ttatctatga agaaaatggc gaattgactg gttatgagat tgaagtcgtt
     1441 cgcgctatct ttaaagattc tgacaaatat gatgtcaagt ttgaaaagac agaatggtca
     1501 ggtgtctttg ctggtcttga cgctgatcgt tacaatatgg ctgtcaacaa tcttagctac
     1561 actaaagaac gtgcggagaa atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc
     1621 cttgtcgtga agaaagatga ctctagtatc aagtctctcg atgatatcgg tggaaaatcg
     1681 acggaagtcg ttcaagccac tacatcagct aagcagttag aagcatacaa tgctgaacac
     1741 acggacaacc caactatcct taactatact aaggcagact tccaacaaat catggtacgt
     1801 ttgagcgatg gacaatttga ctataagatt tttgataaaa tcggtgttga aacagtgatc
     1861 aagaaccaag gtttggacaa cttgaaagtt atcgaacttc caagcgacca acaaccgtac
     1921 gtttacccac ttcttgctca gggtcaagat gagttgaaat cgtttgtaga caaacgcatc
     1981 aaagaacttt ataaagatgg aactcttgaa aaattgtcta aacaattctt cggagacact
     2041 tatctaccgg cagaagctga tattaaataa tttcttgaaa tcatccattc tgagtaaggt
     2101 gggtggtttc tcagttttta gggatatagt tttaaactat atatctgact atctaataac
     2161 aatttgtgaa atcaaacaaa ttgtgagata ctagtacggt attattttta aggagaaaga
     2221 atcatgaaaa tcaaaaaatg gcttggtcta gcagcccttg ctacagtcgc aggtttggct
     2281 cttgcagctt gcggaaactc agaaaagaaa gcagacaatg caacaactat caaaatcgca
     2341 actgttaacc gtagcggttc tgaagaaaaa cgttgggaca aaatccaaga attggttaaa
     2401 aaagacggaa ttaccttgga atttacagag ttcacagact actcacaacc aaacaaagca
     2461 actgctgatg gcgaagtaga tttgaacgct ttccaacact ataacttctt gaacaactgg
     2521 aacaaagaaa acggaaaaga ccttgtagcg attgcagata cttacatctc tccaatccgc
     2581 ctttactcag gtttgaatgg aagtgccaac aagtacacta aagtagaaga catcccagca
     2641 aacggagaaa tcgctgtacc gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt
     2701 caatcagctg gcttgattaa attggatgtt tctggaactg ctcttgcaac agttgccaac
     2761 atcaaagaaa atccaaagaa cttgaaaatc actgaattgg acgctagcca aacagctcgt
     2821 tcattgtcat cagttgacgc tgccgttgta aacaatacct tcgttacaga agcaaaattg
     2881 gactacaaga aagcactttt caaagaacaa gctgatgaaa actcaaaaca atggtacaac
     2941 atcattgttg cgaaaaaaga ttgggaaaca tcacctaagg ctgatgctat caagaaagta
     3001 atcgcagctt accacacaga tgacgtgaaa aaagttatcg aagaatcatc agacggtttg
     3061 gatcaaccag tttggtaata agaaacaggg aggtgggaga gagaattcca cctcttgctt
     3121 ttgtatagag cacggagtgt aaagaagact attcgttcat agaaaggtag agagaatatg
     3181 gtttttccta gcgaacaaga acagattgaa aaatttgaaa aggatcatgt agcccagcat
     3241 tattttgagg ttttgcgtac cttgatttct aagaaatcag tctttgccca gcaggttgga
     3301 ctcaaggaag tcgcaaatta tctgggtgag attttcaagc gtgttggagc tgaagtggag
     3361 attgatgaga gctatacagc gccctttgta atggcacatt tcaagagttc gcgtccagat
     3421 gccaagacct tgattttcta taaccactat gacactgtgc cagcggatgg ggatcaggtc
     3481 tggacagagg atccttttac gctttcggtc cgcaatggct tcatgtatgg gcgtggagtt
     3541 gatgacgaca agggtcatat cacagctcgc ttgagtgctt tgagaaaata tatgcagcac
     3601 catgatgatt tacctgtcaa tatcagcttt atcatggagg gagcggagga atcggcttca
     3661 acagacctag ataagtattt ggaaaagcat gcagacaaac tccgtggggc ggatttgttg
     3721 gtctgggaac aagggaccaa aaatgccttg gaacagctgg aaatttctgg tggcaataag
     3781 gggattgtga cctttgatgc caaggtaaaa agcgctgatg tggatatcca ctcgagttat
     3841 ggtggtgttg tggaatcagc tccttggtat ctcctccaag ccttacagtc tcttcgtgct
     3901 gcggatggcc gtatcttggt tgaaggcttg tacgaagaag tacaagagcc caatgaacga
     3961 gaaatggcct tgctagaaac ttatggtcaa cgaaacccag aggaagttag tcggatttat
     4021 ggattggagt tgcctctctt acaggaggag cggatggcct ttctaaaacg tttctttttc
     4081 gagccagcgc ttaatatcga aggaatccag tctggttatc aaggtcaggg tgttaagact
     4141 attttacctg cagaagccag tgccaagcta gaggttcgtc tggttccggg cctagaaccg
     4201 catgatgttc tggaaaaaat tcggaaacag ctagacaaaa atggctttga taaggtagaa
     4261 ttatactata ccttgggaga gatgagctat cgaagcgata tgagcgcacc agccattctc
     4321 aatgtgatcg agttggccaa gaaattctat ccacagggcg tttcagtctt gccgacgaca
     4381 gcggggacag gacctatgca tacggtcttt gatgccctag aggtaccaat ggttgcattc
     4441 ggtctaggaa atgccaatag ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat
     4501 tattacaccc atatcgaatt agtagaggag ctgattagaa gctatgagta gagatattat
     4561 caagttagat cagatcgatg tgacttttca ccaaaagaag agaaccatca cagcggttaa
     4621 ggatgtgacc attcacatcc aagaagggga tatctacgga atcgttggat attctggagc
     4681 agggaaatca acccttgtac gggtgattaa tctcttgcaa aaaccatctg cagggaaaat
     4741 taccattgac gacgatgtga tttttgatgg taaggtcacc ttgacggcag agcagttgcg
     4801 tcgtaaacgt caagatatcg ggatgatttt ccagcatttt aacctgatga gtcaaaagac
     4861 agcagaggag aatgtagcct ttgcccttaa acactctgga ctcagcaagg aagaaaagaa
     4921 ggctaaagta gctaagttgt tggacttggt tggtttggca gatcgtgctg aaaactaccc
     4981 ttcacaacta tctggagggc aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga
     5041 tccaaaaatc ttgatttcag acgagtcaac ttctgccctt gaccctaaga caaccaagca
     5101 gattttggcc ttgttgcaag atttgaacca aaaattagga ttgacagttg tcttgattac
     5161 gcatgaaatg cagattgtca aagacattgc caaccgtgtg gcggttatgc aggatgggca
     5221 tttgattgaa gagggaagtg tccttgaaat cttctcaaac cctaaacaac ctttgactca
     5281 agactttatc tcaacagcca caggtattga cgaagccatg gtcaaaatcg agaagcaaga
     5341 aatcgtggaa cacttgtctg aaaacagtct cttggtgcaa ctcaagtacg ctggagcttc
     5401 aacagacgag ccacttttga atgaattgta caagcattac caagtaatgg ctaatattct
     5461 ctatgggaat atcgaaattc tcgatggtac tcctgttgga gaattggtgg tggttttgtc
     5521 aggtgaaaaa gcagcgttgg caggtgccca agaagccatt cgtcaagcag gtgtacaact
     5581 aaaagtattg aagggagtac agtaagatgg aatcattgat tcaaacctat ttaccaaatg
     5641 tctataaaat gggttgggct ggtcaggcag gctggggaac ggctatctac ttaactcttt
     5701 atatgacagt tctttccttc attatcggag gcttcttggg gctagtggca ggtctctttc
     5761 tcgtcttgac agcgccaggt ggtgtcttgg agaataaagt cgtattctgg attttagaca
     5821 aaattacctc aatttttcgt gcggttccct ttatcatcct cttggcaatc ttgtcaccac
     5881 tttctcactt gattgttaaa acaagtatcg ggccaaatgc agcccttgtc ccactttctt
     5941 ttgcagtctt tgccttcttt gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg
     6001 gtgtcattga ggcggctcaa gcgagcggag cgactttctg ggacatcgtg ggtgtttacc
     6061 tatcagaagg tcttccagat ttgatccgtg tgacgactgt gaccttgatt tcccttgttg
     6121 gggaaacagc tatggccggt gcggttggag ctggtggtat cggtaacgta gccatcgctt
     6181 atggatttaa ccgctacaat cacgatgtga ccatcttggc aaccatcatt atcattttga
     6241 ttatctttgc aatccaattc ttgggagatt tcttgactaa gaaattgagc cataaataaa
     6301 aaagagccgt gtggctcttt ttaactgatc agattttctg ggcaaatttt ttactcaagg
     6361 cttgtccaat caaggcaccc actagggctc cgatgacaat acttgcgata aatagaagga
     6421 cagttccagg gtttggagtg accatgatac ggtcgatata ttcttgggat tttcctcttg
     6481 ccagaagagt agccatatag gctttgggcg caatccacat aagcaagatt ggtcctgttg
     6541 tactaaaggc gaaaataatg aaagaaagga agttctttgt tttgtccttg tattttccta
     6601 aatgagctac ttcatctgct aggaggccac agataattcc aggaaggaag gaaccagcac
     6661 cgtgtttagt tcccaagaaa aagaaggcaa tgacaaggcc gatagtggta atggctccaa
     6721 agcgcggaac ttttgcgact aggatcatat agacgctacc gccgacaagg gcagtaaagg
     6781 caggcgcata aaacatgttt ccagtttggt caaagagatt gcccaaaagg acaccaatcc
     6841 ccatgcagag gaagtaaaga actgcaaaaa gcagtgtagt taagatagat tttttcatga
     6901 attgtctcct gataattttt tcacaattct cattgtacca cggtttggtg ggattgtaaa
     6961 tggatactag aagtttttga aaacgcttga aatatgatat aatggtttca tagttatttt
     7021 taggggaata tcatgggtag atttttagac tttgtcttta atcgtttctt tttagggatg
     7081 attgcgacag ccttcttttg gctattaact ttagcaggag ggattatcct tggtctagcg
     7141 ccggctagtg ccaccttgat gagcttatat gcagaacatg gttatagctt tcgggaatac
     7201 agtttgaagg aggcttggtc tctttacaag caaaattttg tctcaagcaa cctgattttc
     7261 tatagctttt taggtgtggg tctagttttg acctatggtt tgtatctctt ggtgcaattg
     7321 cctcatcaga ccattgttca tttgattgcg acccttttga atgtcctagt agttgccctg
     7381 atctttttgg cttatacagt atctttaaaa ttacaagttt attttgcctt gtcctatcga
     7441 aatagtctca aattatcctt gattggcatc tttatgagtc tagcagctgt ggccaaggtt
     7501 ctccttggga ctgtgctact tgtagcaatt ggttactata tgcctgccct gctatttttt
     7561 gtaggaattg ggatgtggca tttctttatc agtgatatgt tggaacctgt ctatgaaatc
     7621 atccatgaaa aattggcgac aaaatagaat gaagcagttt tggctacata cgcttctaag
     7681 aacctatagt tcagtgatga tcattatcat tgcgagtttt gcaatcttac tctcttacgc
     7741 tgactgggat tcacgtgaaa aggaagccca gagagtagcc cagcgtgtaa ctgctagaac
     7801 agtgagtgaa attgaatatt accatagaga gtcaacccag atagctcagg ctttagttga
     7861 aaatcaagct cgtatcgagg gaatctataa atactttagc cttagcatgc cagactattt
     7921 ttactggcaa ttagagcgga aagcttcgcc ttatatatca gtctctctgt atgaaaatgt
     7981 tgatgacctc tatgttcgaa atgattttgt aactggggtg gccattgctt ttcaagatta
     8041 caaggaagtc tatgtttcta ctaaagacaa acgtagtgga gaaaaaatca gggctgagga
     8101 tttcaaacca gcaggaaata gttttgccat tccagtgtca gatccagtgt cagatcaaga
     8161 cttaggagtg atttacatct ccttggatcc tgctgtttta taccatgcca ttgataatac
     8221 tagaggtcat actccgatgg cagtaacagt gacctcacct tttgatacgg agatttttca
     8281 tatgggtgag acagttgata aggagagtga aaattggcta gttggcttaa cttctcatgg
     8341 ttatcaggtt caggtggcag ttcccaaaaa ctttgtttta caaggaacgg tgaccagctc
     8401 tgctttgatt gtgggcttga gccttctctt tattgtcatt ctttatctga ctttgaggca
     8461 gacctttgct aattatcaaa agcaggtagt ggatttggtg gattccatcc aagctattgc
     8521 ccaaggacaa gaaggtcttc gcattgatac gcttgaaaag gatcaggaat tgctcctaat
     8581 cgcggagacg accaatgata tgttggatcg attggaaaag aatatccatg atatttacca
     8641 gttagaactc agtcaaaaag atgccaatat gcgggccttg caggcgcaaa tcaaccctca
     8701 cttcatgtat aatacgctgg agttcttgcg tatgtacgca gtcatgcaga gtcaagatga
     8761 gttggcagat atcatttatg aattcagtag tctcttgcgt aacaatattt ccgacgaaag
     8821 agagaccctc ctcaaacagg aattagaatt ttgccgtaaa tacagctatc tctgcatggt
     8881 tcgctatccc aagtccattg cctatggttt caagatagat ccagagttag agaatatgaa
     8941 gattcccaag tttaccttgc aaccgctggt agaaaactat ttcgcgcatg gtgttgacca
     9001 caggcggaca gataatgtga ttagcatcaa ggctcttaaa caggatgggt ttgtggaaat
     9061 tttggtggtc gataatggta gaggaatgtc ggctgaaaag ttggcaaata tccgagaaaa
     9121 attaagtcag aaatattttg aacaccaagc cagctacagt gatcaaaggc agtctatcgg
     9181 gattgtcaat gtacacgagc gttttgtgct ctattttgga gaccgctatg ccattactat
     9241 agagtctgca gagcaagccg gtgttcagta tcgtattaca attcaagatg agtagaaagg
     9301 gagaaaatgt ataaagtatt attagtagat gatgagtaca tggtgacaga aggtctgaag
     9361 cgtttgattc cctttgataa gtgggatatg gaggtcgtcg caacagccag tcatgccgat
     9421 gaagctctag aatatgttca ggaaaatcct gtcgatgtca tcatttccga tgtcaatatg
     9481 ccagacaaaa cagggcttga tatgattcgg gagatgaaag agatcttacc agatgctgcc
     9541 tatatcctgc tctcaggtta tcaggagttt gattatgtaa aaagagcaat gaaccttagt
     9601 gtggtggact atttggtcaa gcctgttgat aaggtagagc tgggaaatct gctggagaag
     9661 attgcaggtc agctcggcga gagagggaag aaaagtcaga ctcttagtca agaattagac
     9721 gaggctggat ttgttagtta tttaggggat aaggagaatt ggtggatagg tctatccaag
     9781 gaaaaacaag gttccttcac cattccctac tatgtcttgg gccaagactg gcagattttc
     9841 atttctgacc aacccctaga tggtttagtc gttacacctt ttgaagctcc ttatcaagaa
     9901 cactttgaac gctggaagct gaatgctgag aaaaccctct tttacggttc tgtaaatttg
     9961 cagcagtctg agagtctctt tgcctattac gaaccgattt atagggttat tattcaggga
    10021 aatctcaatc aaatcgtaga agagttaaat ctcttggaga aggtagttct tgaaaatacg
    10081 ccgcgtgttc cgattactaa acagcttttt attcagtttg tcatggatgt tttccattta
    10141 tttgaacatc tcaaagctga tgacctgaca gacatcgtca aaaccattca tgctattcaa
    10201 tccttcgatg aattggttcc ttatatcaag gaaactctga gcagcttttt cggtcaatac
    10261 cgtatgaatg aaaatgtggt cagtgtgctg gaagtcattg gtcgtgatta ccaaaaagag
    10321 ctttccctca aggatatcag taaggctctc tttatcaatc ctgtctatct agggcagttg
    10381 attaagcgtg aaaccgattc gacttttgca gagttactaa acaaacaacg tattaaggct
    10441 gcccaacaac ttttgctttc aactagtgac agcatcgaag atatttgtta tgctgttggt
    10501 tacagtaacc ttggatattt ctataaagtt ttccgaaaat tgtgcggaaa atcgccaaaa
    10561 gcctaccgaa aacaggtaga aactatacta taagatttgt attcctttac aaaaggtgct
    10621 ataatattat caggaggtcc tatcatgaaa aagaaaccaa tttatctatg ggttttgcta
    10681 atcttgtctg cccttatttc agttccgtct ctgtttggaa ttgtgagtcc cttgcctagt
    10741 aaagaagccc ttcgtgctgc tcagaaacaa gttgcagggg tcaatgctca gcaattagaa
    10801 gaccagctta attataccta tagagtagca gaagcatctc attctatttt taatgttgct
    10861 ttgattgtgc tatctactat tttagtggtc gtagcgattg tcttccttgt tcgtaaaaat
    10921 ttgcaatatg caaactatac ttacgttggc tatgttttgt tagctattat tggttcgatt
    10981 tatggctatg ttggtttaca agacgctgtg cagttggttc aagatgagag catgcgtttg
    11041 acagtgagta ttggttcaaa agctgttagc attttctata tcgtcatcaa tgttctcttc
    11101 ctagcccttg tcttctataa gatgtggcga caacagaaag ccttggcaga agaagaggaa
    11161 acagaagagc ttacctaagt attgacaaaa aagaactatc aagatacaat cttggtagtt
    11221 gttttttgat tatagataaa atcatggagg tacatatgaa gacaatttct ttagtttata
    11281 ttagtttgag tggcaacact gaaagttttg tgacgcgctt gaaagactat ctcttgtccc
    11341 agtacaaagg gattgaggtt caaaagattc atatcaagga tttggtcaag gaaggcaaaa
    11401 atttctatga aatggaccat ccctatgtcg cttttttgcc gacctatctc gaaggtggga
    11461 atggcgtgga taacggagat gttgagattt tgacgacacc ggtgggagat tttattgcct
    11521 atggtaacaa tgctagtaag tgttttggtg tggttgggtc aggaaatcgt aactttaata
    11581 accaatactg cctaacagcc aagcaataca gtcaacgctt tggcttccct gtattggctg
    11641 actttgaaat gcgaggcatg ctggaagata tcaaacatgt cgcagctatt atcgcagatt
    11701 tgtatgagtt ggaaaaggag aattaatact caatgaaaat caaagagcaa actaggaagc
    11761 tagtcgcagg ttgctcaaag cacagctttg aggttgcaga tagagctgac gtggtttgaa
    11821 gagattctcg aatagtataa agttcttata agaggtggtt gaagttgttc aactgttttt
    11881 tgagtataaa cagtctttaa gaacgtaaaa aagcataagt tcaggtcttc aaaaccttgt
    11941 tcttatgctt tttatcatag aaatatttgc tgaattttct cttgaaatga aaccttatct
    12001 tcatctcgcg cttgtccctt accctgcttt tccgattgcg agtgcgtaga taaagaagat
    12061 ggcgaagcca aagaggaaaa tcaatcccgc aatggcaagg tgtttgagcc aagaaggaag
    12121 atttttgttt tcacgcgtta ccaaggcgta attcaaaaga gcaaagaaag gtgttgtcag
    12181 gaaagagcca atcatggcaa agcggagcat ggttgaaacc tgaccagcga agaacttgat
    12241 aatgacgata ccgatgatag cagtgatggt catccagatg ttcaaagatt tacgattgtc
    12301 ctctttttga ctgattagca gtcggagaga ttcctgatta acgcgagaat agccatcgat
    12361 aacagttata actgttccaa agatacagag gaaggcaata aaggtaatca agtaacggga
    12421 ccattcgcca agaacagagg catacatgcc cacgaattga gagatgtatt tggctgaagc
    12481 agcttcaacc gcctgccctg taggatactg aatcagtgct cccagtgcca caaagaagac
    12541 ggctaggata gctgttccaa tataaccagt gttaaagtca aacagagcgt cttctgtgtt
    12601 aaagttgacg gtctttctct tttcagctga ccaaagtgaa ttgatggctg aaatttcaat
    12661 aggagccggc atccatccta ggagggagac gatgaagggc agagctgcca tttgccaagg
    12721 tgtcttctcg acaaaatcag aactgtattc tggatgcttg accgccgcaa tgataactgc
    12781 aagaacagtc gcaatggtta aggcagacat aatccatttg accatgccgt ctaaaagttt
    12841 gtagcctcca aagagtagca tagcccaaat gattgcaacg agaatgaggg accactgagt
    12901 aatgctaagt ccaatcattg ggaaggcact ggcgatgata gctgagcaca gaatggcaac
    12961 accagccgtg ttgaccatag ccgaaaagac attgaggata aagaaaatcc agagatagag
    13021 ttttcctttt tcggcataac cttcaaccaa agtctttcca gtatcagctg tgtattcagc
    13081 accaaaacgg aaaaatggat atttaaagac attggctaag atgaccaaga gaagtagaga
    13141 ccaaccgtaa gaaccgccag cttgagttga ggatacaatg tgggaacctc caacagcggc
    13201 agttgccatt aggattccag gtcccattgc ttttagcttg cttgcccagg ttgattgatt
    13261 taaggaaata gcttgcgaca tgataaatac tcctttttga attttcagaa taatctgtat
    13321 atgtaatcta tattctacaa aaaattttgg aaaaatgcaa gagtattttg aaaaaagata
    13381 gaaaatttac aaagaaaatc tgaaataact gttatgatat agaggattga aactagaata
    13441 gtacacctct gcttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttatc
    13501 ctgttcttat ttcatttcac tatagtaagg tgcagcagga taaagaaaaa ccgagaagtt
    13561 tctttctcgg atttgcttat tatgaggttc ctattttcta tgctccaaga gttgattgat
    13621 gtgatctact tttttagcct ctcttttata gagaatagcc cagatgatga gatagacaat
    13681 cgcaaactcg ataatgagct ggaggtagaa aatccagtgg aaagggaacc aaccagcaag
    13741 agttgctagt gggacaaagc cagccagcat aaggaagaaa tgagtcagag tggcacgaag
    13801 catgctccag tcacggctaa ataagcggtt gccaaagttg aagagcatac cgatggttgc
    13861 ccagataagt gtgcagtaga gcaagaccag ggcaccgtga acctgatgct gatccatcac
    13921 ttggccgatg agagagtagg gatttagtgg tgcgtaggta tttggtgcat aaatgagtga
    13981 aaagaggata gagaggatga ggccgataag aacaccggta gctgcatcgt gaaatacttg
    14041 ttttttcata gttctaattt ctccttgatg gtttttagat aacggcgtga agagtaggtg
    14101 aagctttcgt ttttcaagaa aatttctacc agaccgtttg gcgtgagctt gaggtgagag
    14161 atggaatcga tattgatgat ttctgattgg gaaatttgga taaaattggt tggcaagagt
    14221 ttaagaacct gatagagtcg caaatcaatg ctgtaggtct gactcgcggt ttctgctaga
    14281 accttccgat tctcgatata gaagcgctga atcttgccaa tctcaactag atagacctga
    14341 tcatcgattt ttcctttgat tttttctctt tggtccagat tttctgcgaa ctcgatgact
    14401 ttctggactt tttcggtttc ttgaggtgct tggacaatca gcttttcctc ctcgtaagtc
    14461 tcactaatct gtagttctac tttcataaat ttctctcctt gtttttcata caaaattaat
    14521 ctcacttctt gtacaccttt attaatactc ttcaaaaatc tcttcaaatc acgtcagcgt
    14581 cgtcttgccg taggatagtt gttgactttg tcagttttat ctacaacctc aaaacagtgt
    14641 tttgaactgt ctgcgcctag ctttctagtt tgctctttga tttttattga gtataccact
    14701 attttactcc ctctggcaag ggactttgtc tatgtggagg gattgggctc ctatgtggtg
    14761 gagcttttct gttctttctg aaatatggta taatagcact aattaatttc taggaaaata
    14821 gatacagaaa ggggctgaaa gatgtctcat attattgaat tgccagagat gctggcaaac
    14881 caaatcgcag ctggagaggt cattgaacgt cctgccagtg tggtcaaaga gttggtagaa
    14941 aatgccattg acgcgggctc tagtcagatt attattgaga ttgaggaagc tggtctcaag
    15001 aaggttcaaa tcacggataa cggtcatgga attgcccacg atgaggtgga gttggccctg
    15061 cgtcgccatg cgaccagtaa gataaaaaat caagcagatc tctttcggat tcggacgctt
    15121 ggttttcgtg gtgaagcctt gccttctatt gcgtctgtta gtgtcttgac tctgttaacg
    15181 gcggtggatg gtgctagtca tggaaccaag ttagtcgcgc gtgggggtga agttgaggaa
    15241 gtcatcccag cgactagtcc tgtgggaacc aaggtttgtg tggaggatct ctttttcaac
    15301 acgcctgccc gtctcaagta tatgaagagc cagcaagcgg agttgtctca tatcattgat
    15361 attgtcaacc gtctgggctt ggcccatcct gagatttctt ttagcttgat tagtgatggc
    15421 aaggaaatga cgcggacagc agggactggt caactgcgcc aagcaatcgc agggatttac
    15481 ggtttggtca gtgccaagaa gatgattgaa attgagaact ctgacctaga tttcgaaatt
    15541 tcaggttttg tgtccttgcc tgagttgact cgggctaacc gcaattatat cagtctcttc
    15601 atcaatggcc gttatatcaa gaacttcctg ctcaatcgtg ctattttgga tggttttgga
    15661 agcaagctta tggttggacg ttttccactg gctgtcattc acatccatat cgacccttat
    15721 ctagcggatg tcaatgtaca tccaaccaag caagaggtgc ggatttccaa ggaaaaagaa
    15781 ctgatggcgc tggtctcaga agctattgca aatagtctca aggaacaaac cttgattcca
    15841 gatgccttgg aaaatcttgc caaatcgacc gtgcgcaatc gtgagaaggt ggagcaaact
    15901 attctcccac tcaaagaaaa tacgctctac tatgagaaaa ctgagccgtc aagacctagt
    15961 caaactgaag tagctgatta tcaggtagaa ttgactgatg aagggcagga tttgaccctg
    16021 tttgccaagg aaaccttgga ccgattgacc aagccagcaa aactgcattt tgcagagaga
    16081 aagcctgcta actacgacca gctagaccat ccagagttag atcttgctag catcgataag
    16141 gcttatgaca aactggagcg agaagaagca tccagcttcc cagagttgga gtttttcgga
    16201 caaatgcacg ggacttatct ctttgcccaa gggcgagatg gactttacat catagatcag
    16261 cacgctgctc aggaacgggt caagtacgag gagtaccgtg aaagcattgg caatgttgac
    16321 cagagccagc agcaactcct agtgccctat atctttgaat ttcctgcgga tgatgccttg
    16381 cgtctcaagg aaagaatgcc tctcttagag gaagtgggcg tctttctagc agagtacgga
    16441 gaaaatcaat ttattctacg tgaacatcct atttggatgg cagaagaaga gattgaatca
    16501 ggcatctatg agatgtgcga catgctcctt ttgaccaagg aagtttctat caagaaatac
    16561 cgagcagagc tggctatcat gatgtcttgc aagcgatcta tcaaggccaa tcatcgtatt
    16621 gatgatcatt cagctagaca actcctctat cagctttctc aatgtgacaa tccctataac
    16681 tgtcctcacg gacgtcctgt tttggtgcat tttaccaagt cggatatgga aaagatgttc
    16741 cgacgtattc aggaaaatca caccagtctc cgtgagttgg ggaaatatta aaagtataaa
    16801 aaagtctggg aaaaattttc aaaatcagaa aaacgcataa aatcaggtgt tcaaaaacct
    16861 tgatttttat gcgttttatc atggaaatag ttacttcatt ttttcctaat tcttttcgaa
    16921 actcttttta aacgacgtca gttttatcag taatctcaaa acagtgtttt gagctaattt
    16981 tgccagtttt gtctgtaaca tcgaagttgt gttttaccac tctgcgactg gtttcctagt
    17041 ttgctctatg attttcacag agtattaaat tgcgattttg ccaagtttct ttattcgtct
    17101 aaaagtagag tctgttctat gcgtctaatg tacgaattag gttgaccatt tcaatagctc
    17161 cttgtgcaca ctcagaaccc ttatttcctg ctttggtacc agctcgttct atggcttgtt
    17221 caattgtatc tgtcgttagc acaccaaaca taacaggaat ttcgctattt aaactgattt
    17281 gggcgattcc cttagatacc tcgctacata cataatcata atgacttgta ttccctctaa
    17341 tgacagctcc caagcagata attgcatcat attttttact ttttgccatt tttgatgcaa
    17401 tcagtggtat ttcaaaagct cctggaaccc aggctacctc gatatctttc tcgtttacat
    17461 tctctctttt gagattatct agtgctccag ataataattt tgaagttata aattcattaa
    17521 atctcgctac aacaatacct attttaatat tgtttgctac taaattacct tcataagtgt
    17581 tcatttattt ttcctccata tttaaaatgt gacccattcg atttttcttt gtttctaaat
    17641 aaaaactatt gtaaggattg gcttctattt cgattgatat tctactggaa atggtaattc
    17701 catatttttc taactgttca accttgtcag gattatttgt cagtaaatga agtgactgaa
    17761 gtcccagatc tttaagcatt tgtgctccaa tatgatattc tcttaaatca ccttcaaagc
    17821 ctaatgcaag attagcatca agcgtatcca tgccttgatc ttgtaaatga taggctttta
    17881 atttattgat aagtccaatt cctcgtccct cctgtcgcaa gtaaagtaag acacccgaac
    17941 cattctcaac aatcattttc atagctttat cgaattgctg tccacaatcg caacgtaaag
    18001 agcctaaaat atcccctgtt aaacattcgg agtggacccg acataataca ttggcttcat
    18061 cctctatgtt tcccataata agagcaagat gatgttcccc atttagttta tctatatagc
    18121 taattgcttt gaaattaccg tatctagtag gcatattgac agttgaaact cgttctacca
    18181 gctgatcata tacttttcta tattcttgta attctttgat ggtaattagt ggaatgttgt
    18241 gtttcttcga gaactgaatt aaatcatctg ttctcatcat tttgccatca tgattcatta
    18301 tttcacaaca taggccacac tcttttagtc cagctaattt taataaatca acagttgctt
    18361 ctgtgtgtcc atttctttct aggacaccac ctttttttgc aattaaagga aacatgtgtc
    18421 ctggcctgcg aaaatcagag ggtgttatat cttcagctac acacatacgt gcggtcagtc
    18481 ctctttcctc ggcagaaata cctgtggtcg tttctttata atcaattgaa actgtaaaag
    18541 cagtcttatg attatctgta ttgttttcaa ccataggtga aagcattaat tgattagcta
    18601 aactttcgct cataggcata caaattaatc ctttggcata agtagccata aaattaacat
    18661 tttctgttgt agctgcttgt gcagaacaaa ttaagtctcc ttcattttct ctatccttgt
    18721 cgtctataac aagaacaagt cgtcccttct gcaatgcttc taatgcttct tgtatttttc
    18781 gatattccat tgactaatta tcctttctgc taaaatccat tttgatataa tagttcctta
    18841 gatatttctg attttggaga gttatccatc agtttttgca catatttacc taagatatca
    18901 ttttcaagat ttactgtact cccgacttgt ttactcttaa gaatggtttg ttccaaggta
    18961 tgagggataa cagatactga aaagtttact ttggagactt tagcgacagt cagactaatg
    19021 ccgtcaattg taatagatcc tttttcaact attaaatcta aaatttcttt ttgtgtgttg
    19081 atttgatacc atacagcatt atcatctttt tttattgacg agatttttcc tgtaccatca
    19141 atgtgtcctg taacgacgtg acccccaagt cgaccgttga cagataaggc tctttctaga
    19201 ttcacctcac ttccatgttt taatagagta agagctgttc gactccatgt ttcattcatt
    19261 acatcaactg taaaggattg atgattgaaa tgagtaactg taagacagat accatttact
    19321 gctatactat cgcctaaatg gatatccgtt aatatttttg aggctttaat tgatagttta
    19381 caattacgag agtctttctg tattctttca acttttccga tttcttcaat tattcctgtg
    19441 aacatggata aatcacttca ctttctatga gatagtcatt tcctatttga gaaaaagtat
    19501 aaggtttcaa tctaatagcg tcatttggca aagaaatgcc ttcacctccg acaggaaact
    19561 tggcactgcc tccaaaaatt tttggtgcaa tatatatttt cagctcatca acaatttgtt
    19621 gttccaaagc actccaattc attagactgc ccccttctag aactaggcta tcaatctgca
    19681 tgtttcctag atgttgcatt aaactcgata agtctatatg attgcctttt ttctttatgg
    19741 aaagtatttc acagccatga ttttgatata gcttcatttt atttttgtct tcagaggaag
    19801 tggcaatgta agttttaata tcatttgctg tttttacgat tttagaggta agaggagttc
    19861 gtaaatgtgt atcgcatatg atacggatag gatttttccc ttcctccaat ctacatgtca
    19921 gcaaaggatc gtcttgaata acagtattga ctcccaccat aattgcacta acatggtgtc
    19981 gtaactgatg cacgtgcttt cttgcttctt cttcagtaat ccatttggat tgatttgttt
    20041 tagtggctat ttttccatcc attgacattg catatttcat aaaaacatag ggtacatgct
    20101 gggtaatata ctttctaaaa ctttttatta agttaagaca ctcattttct aaaattccaa
    20161 cagtaacttg aagattattt tcctcaagta tctttactcc ttttccagat acaataggat
    20221 tacagtctag gcttccaatg actactcttg taataccact atcgattata gcatctatac
    20281 agggaggtgt tttcccgaag tgacaacagg gttcaagtgt tacataaagc gtcgctccga
    20341 caggggattt tctacagttt ttaagagcat ttctctcagc atgtgggcca ccaaaaaact
    20401 catgataacc ttgtccgata atgtgattat cttttacaat aattgcgccg accataggat
    20461 tggggttgac gtaaccagcc cctttttgtg ccaattttat tgctaatttc atatattttg
    20521 aatcgctcat ctcgctacct ccaaaaaaat ataccttgaa taggggacta ctcaaggcat
    20581 acaaaagaaa acttatgcga ttaacaaaaa tgctctgaaa tgacaagtaa tcatttcaga
    20641 gcacgcaaaa agcacaaata tacttttatc ttctttcatc cagactatac tgtcggcttt
    20701 ggaatttcac caaatcatgc ctttcggctc gtgggctata ccaccggtag ggaattgcac
    20761 cctgccctga agatagttat tcaattacag atgattatag tacttaattt tgaatatgtc
    20821 aacagataaa taccgattgt ttttgatata ctgtatttgt gataatcgat tctcgctcct
    20881 cggataaaga aaatatgata tactagataa acgaaataag agagaaggaa cactatgtac
    20941 gcatatttaa aaggaatcat taccaaaatt actgccaaat acattgttct tgaaaccaat
    21001 ggtattggtt atatcctgca tgtggccaat ccttatgcct attcaggtca ggttaatcag
    21061 gaggctcaga tttatgtgca tcaggttgtg cgtgaggacg cccatttgct ttatggattt
    21121 cgctcagagg atgagaaaaa gctctttctt agtctgattt cggtctctgg gattggtcct
    21181 gtatcagctc ttgctattat cgctgctgat gacaatgctg gcttggttca agccattgaa
    21241 accaagaaca tcacctactt gaccaagttc cctaaaattg gcaagaaaac agcccagcag
    21301 atggtgctgg acttggaagg caaggtagta gttgcaggag atgaccttcc tgccaaggtc
    21361 gcagtgcaag caagtgctga aaaccaagaa ttggaagaag ctatggaagc catgttggct
    21421 ctgggctaca aggcaacaga gctcaagaaa atcaagaaat tctttgaagg aacgacagat
    21481 acagctgaga actatatcaa gtcggccctt aaaatgttgg tcaaatagga gcagagaatg
    21541 acaaaacgtt gttcgtgggt caagatgacc aacccgctct acatcgccta tcatgatgag
    21601 gagtggggcc agcccctcta tgatgaccaa gcattgtttg agttgttgtg tatggaaacc
    21661 tatcaggcag gcctgtcttg ggaaacggta ctcaacaaac gccaagcttt ccgagaagcc
    21721 tttcatagct atcaaattca ctcagtcgca gagatgactg acactgaatt ggaagccatg
    21781 ctggagaatc cagctatcat tcgaaataga gccaagattt ttgctacacg cgctaacgcc
    21841 caagcttttc tacagttaca ggcagagtac ggctcttttg atgcctatct ttggtctttt
    21901 gttgagggga aaactgtcgt taacgatgtt cctgattatc gccaagcccc agctaaaaca
    21961 cccttatctg agaaattagc caaagatctc aaaaaacgag acttcaagtt cacaggccca
    22021 gtcgccgtat tgtcttttct acaggctgca gggctagttg atgaccacga gaatgattgt
    22081 gagtggaaag gtcttaaatg atgtctaaca aaaataaggg aattctgatt tttgcgattc
    22141 tctatacaat cctctttgtg tttgatggcg ttaaattgct ggcttcttta atgccatctg
    22201 ccattgcaaa ttatcttgtt tatgtagttt tagctttata tggctccttc ttgttcaagg
    22261 atagattgat ccaacaatgg aaggagatta gaaagactaa aagaaaattc ttctttggcg
    22321 tcttaacagg atggctcttt ctcattctga tgactgttgt ctttgaattt gtatcagaga
    22381 tgttgaagca gtttgtggga ctagatggac aaggtctaaa tcagtctaat attcaaagta
    22441 cctttcaaga acaaccacta ctgatagctg tttttgcttg tgtcattgga cctctggtag
    22501 aagaattatt tttccgtcag gtcttattgc attacttgca ggaacggttg ccaggtttac
    22561 taagcattat tctggtagga cttgtttttg ctctgactca tatgcacagt ttggctctat
    22621 cagagtggat tggtgcagtt ggttacttag gtggaggcct tgccttttct attatttatg
    22681 tgaaagaaaa agagaatata tactatcccc tacttgttca catgttaagc aacagcctct
    22741 ccttaatcat tttagctatc agtatagtaa aatgaaatga gaacaggaca aatcgatttc
    22801 taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatatattgt aatatgtgat
    22861 gaaaatgcca gtaatgatac cgagaaaaaa gctgagaaac ttttcccagc tttatttgtt
    22921 atagtcaaag agaatgactt gttcctgtgc atctacatga gcatggaccc caaagggtac
    22981 aattgctctt ggagttgcgt ggccgacatt cagattatag acaatcggga tattgctgtc
    23041 aatgatatcc aatagtgcct ctttatagtc gtcatggaaa gtttcatcca taggttttcc
    23101 gaccaagagt ccattgatga ccgcgaatat gccagtgtcc tttaaagtta gcaacatctt
    23161 tttgaagtct tctggcttag gcttttcttc gcttgtttcg agcaagagga ttttcccttc
    23221 ccagtctgac aagtcaggga aaagtttgta tttttggcag agttccgtgc tatctgcgta
    23281 tcgagagttg tcaaagatat cgtagaggga ttcgaggcaa ccaccgagga ttttcccctc
    23341 gaactgggca cttccttgca acaagtcaaa acctgtattt gtatgactga cacgaggtgt
    23401 tcccagggcc gtgggactaa aatcagttcg ttcctcatac caaacgtcac tagggcggat
    23461 ttctgaaatt cttcccgtct caatcaattc tttaaagtag tgaaggctat aggctagcat
    23521 ttctttgtct aattcacaaa tgtctgctaa aaaggattga ccataaaaag tcttgattcc
    23581 taatttatgc aacatgaggt ggttcatggt tgtatccgag aagccaagaa aaattttttg
    23641 tttgataacc ttttggagtt ggtcattttc aaaaagataa ggtagcaagc gataggcatc
    23701 gtctccaccg atggcacata ggatcatgtc gatgctatca tcagaaaagg catgaatcaa
    23761 atcctctgca cgagcttcag gatggtcctt gataaagtct aatcctttta acgaatgggg
    23821 caaaaagatg ggattgagtc ccagatcctt gagacgttgg atacccaagt ccacttcgtg
    23881 tttgacaaaa tcctctccga taatgccact agataaacta acaataccaa tagtagaaac
    23941 catatctcat cctcctagaa atagattgag cctattttat cacaaaatat aagagaaagc
    24001 tatgtgggat ttcagaagaa tacttttaat actcttcgaa aatctcttca aaccacgtca
    24061 gttttatttg caacctcaaa gctgtgcttt gagcaacctg cagctagctt cctagtttgc
    24121 tctttgattt tcattgagta taactcaaaa aagtaagtga aaaagcaacc gcacctgcag
    24181 ttgcttttat cgttttctta ttcttgatag cgtgttggtc ctgcacttgc actacggata
    24241 ttcaagcgtt tcttgagata gaagcgaagg gctaggaggg ctgctccaat aatagctagt
    24301 ggcaatggat ccagtactgg gttaaggcta gctggtagga agcttgttgc aaagaagaca
    24361 agcaaccaaa ggaacataga agctaggata actagtacag atttccagaa aggtggacgt
    24421 tgactgcaat ctatatctgg tccatagtat tggtaaacaa agtagtacat caagtagaag
    24481 gcaaatccac caaccagtcc aactaataga agagtaatca atccatagcc gaaagcttga
    24541 tctgccgcaa agaaggttgt gagggcgctg acaagggcaa agaggctagt gatgaaaaga
    24601 gctgagtcca taatcatcag ttttggatca tcattttctt ttggatgctc tttttcgtac
    24661 tgctctttga cagtgaagct atgagcccaa tgagttggtg cgccgtatag ggaacgggca
    24721 gttgtacctt tagattgctc ctcaaggatt tggggaatga cttcctcaaa aatagtctgg
    24781 atttcagcgt ctgttttccc atctttgatg aattgttggg tagcaatgtg gacaaactct
    24841 tggtttttct tagttaattt ttgtagatca atttgagaca taggaactcc tcttagaacc
    24901 attttttatg gatgagatag agagtgagcg agacactcat agcaaaggcg ataaagacga
    24961 ttaaccagaa ggcatttggc tctccgttta gggggatttc attatcctta aagttcatcc
    25021 cgtaggcaga aaagaccatg gttgggatgg acatgacgat ggtcacaagg gccaaggttt
    25081 tcatgatgtt gttctggttg ttagaaatga tagaggcaaa ggtctctgtc atagaatgca
    25141 agacgtttcc ataaatatct gccatctcga tggcctgttg ggtttcaatc agggtgtctt
    25201 caagcaggtc ttcgtcctca aggtatttct tgatattgct ggttgaactg gtcaatttct
    25261 taatcacgcg ctcatttgtt ttgagggagg ccttgaaata gacgatagtt ttttccaatt
    25321 ccatgagctc aatcaattct tcattacgag ttgattgatg cagttgactt tcgatttgtt
    25381 cactcttgcg gtcgattgaa cgaagggctg ttaggtaaag ctctgcattg cgataaagaa
    25441 tttgaaagat aaaacgtgaa cgcatgaagg tatagaaatt acgcaatcga cggttgataa
    25501 agacatcaag gacaggtagt ggttccaaac acgtagtgat aatggtttcc tcagtgatga
    25561 taataccaag cgggatggtt acgtagtagg tgcggttatt tctttcctcc gtgaccggca
    25621 cgtctacgat aatcagggta tactcgtctt caatggtaat acgagacatt tcttccgcat
    25681 cgagcggtgc tcgaaggtcg gcaatatcaa tatcgaaggt gttggcgatt tcgagtgatt
    25741 cattttgagt cggattgacg agattgatcc aagtacccgg ttcaagcgta tcgatctctt
    25801 taaattcagt tgttgtagag agaaaaactt gtttcatatc ccttatcctt tctcattttt
    25861 cagatttttt cacactgtac tattatacta caaaatcggc cttttgggta atagaatctc
    25921 actttttttg gtataatggt aagcaataat ggactagaaa gaacaaagat gcaagataaa
    25981 attgtcattc atggggcgcg tgcccataat ttaaaaaata ttgatgtgga gattccgcga
    26041 gacaagctgg ttgtcgtgac aggtttgtca ggttcaggga aatccagtct ggcctttgat
    26101 accctctatg cggagggaca acgtcgctat gtagagagtt tgtcagccta tgctcgtcaa
    26161 ttcttgggaa atatggagaa gccggatgtg gatgccattg atggtctcag cccagctatt
    26221 tctatcgacc agaaaacgac tagcaaaaac cctcgctcga cggtgggaac aacgactgaa
    26281 atcaatgact atctgcgtct cctctacgcg cgtgtgggga cgccttactg tatcaacgga
    26341 catggagcta tcaatgcttc ttctgtggag caaatcgtgg ataaggtctt ggaactgcca
    26401 gaacgtcagc gcctgcaaat cttagctcct gtcatccgca agaaaaaagg acagcacaag
    26461 agcgttgttg aaaagattca gaaagatggt tatgttcgtg tccgtgtgga tggggaagtc
    26521 tatgatgtga ccgaagtgcc agacttgtcc aagagcaagc aacacaatat cgatgtcgta
    26581 gttgaccgta ttgttatcaa ggagggtatc cgtagtcgtc tctttgattc cattgaggct
    26641 gcccttcgta ttgcagaagg ttatgtcatt atcgatacta tggacagttc tgagttactc
    26701 ttctctgagc attatgcttg tccagtttgt ggatttactg tcccagagtt agagcctcgt
    26761 ctcttctctt tcaatgctcc ttttggctct tgtagtgagt gtgatggctt gggcatcaag
    26821 ctggaggtgg atactgattt ggtagtacca gatgccagca aaaccttacg tgagggggcg
    26881 ctagcacctt ggaatcctat ttcatccaac tactatccaa atatgctaga gcaggccatg
    26941 acagcctttg gagtggagat ggataagcct tttgaggact tgtcagaaga agataagaac
    27001 ttgattcttt acggttcaga tggcaaggaa ttccatttcc actatgaaaa tgaatttggt
    27061 ggcgtgcgcg atatcgatat tccttttgag ggagttgtta ataatatcaa gcgtcgctat
    27121 catgaaacta atagtgacta cacccgcacc cagatgcgcc tttacatgaa tgagctgacc
    27181 tgcggaacct gtcacggcta tcgcctcaat gaccaggcct tgtctgtccg tgtgggtggc
    27241 gagaacgggc cacatatcgg agaaatttca gacctgtcta tcgcagacca cttggacttg
    27301 gtaagccagt tgactctatc tgaaaatgaa gccatcattg ctcgccctat tctcaaggaa
    27361 atcaaggacc gtttgacttt cctcaataac gtgggtctta actatctgac tctgtctcgt
    27421 tcagcaggaa ccctttcagg tggggaaagt cagcgcattc gtttggcaac ccagattggt
    27481 tccaacctat caggcgtcct ctatatccta gacgagccgt caatcggtct tcaccagagg
    27541 gacaatgacc gcctgattgc cagtctgaaa aagatgcgtg acttgggcaa tactcttatc
    27601 gtggtggaac acgacgaaga taccatgcgt gaagctgatt atctgattga cgttggtcct
    27661 ggtgccggtg tttttggtgg tgagattgtt gcagcaggta cacctaagca agtggctcgc
    27721 aacagcaagt ctatcacagg tcagtacttg tcaggcaaac gtgtcatccc agtaccagaa
    27781 gagcgccgtg tcggaaatgg tcgttttatt gaagtgatag gagcgcgtga gaacaacttg
    27841 caaaatgtca cggctcgctt tccactagga aaatttatcg cagtgacagg tgtgtcgggt
    27901 tcagggaaat cgactctaat caacagcatt ctcaaaaaag ccattgccca gaagctcaac
    27961 cgtaattcag acaaacctgg taagtttaag actattacag ggattgagca tgtcgaccgt
    28021 ttgattgata ttgaccagag ccctatcgga cggacgccga ggtctaaccc agctacctat
    28081 acaggagttt ttgacgatat acgtgacctt tttgctcaga caaatgaagc caagattcga
    28141 ggctacaaga aggggcgctt cagtttcaac gtcaagggag gtcgctgtga agcttgctca
    28201 ggtgacggga ttatcaagat tgagatgcac ttcttgccag atgtttatgt ggcttgtgaa
    28261 gtttgccacg gaacccgcta taacagtgaa accctagaag ttcactacaa ggaaaagaat
    28321 atttcgcagg tcttggatat gacggtcaac gatgcggtag aatttttcca acacattccg
    28381 aaaattcaac gcaaactcca gaccatcaag gatgtagggc taggctatgt gaccttggga
    28441 cagccagcta ccaccctttc tgggggagaa gcccaacgta tgaagttagc tagcgaactc
    28501 cacaaacgct cgacaggaaa atctttctac attctggatg agccgacgac agggcttcat
    28561 acagaggaca ttgctcgcct gctcaaggtt ttagctcgct ttgtagacga tggcaataca
    28621 gtcctcgtca tcgagcacaa tctggatgtt atcaagacgg cagaccatat cattgacttg
    28681 ggacctgagg gcggtgtcgg tggtggaacc atcatcgtaa caggaactcc agaagaagta
    28741 gctgccaacg aagccagcta tacaggacac tatttgaaag gaaagttaca tcatgaataa
    28801 acgcgtacaa gcatttctag ctaaaatgca agaaaaagaa ctagatggtg tcatcatcaa
    28861 caatcttaaa aacgtctatt atttgactgg tttttggggc tcaaacggaa cagtctttat
    28921 cagccgtgac cgtcaggtct tagtgacaga ctctcgctat atcatcgcag ctaagcaaga
    28981 aaccagtggt tttgagattg tggctgatcg tgatgaattg gctgtcattg caggaattgt
    29041 taaggacatg ggcttgactc gtatcggttt tgaagatgag atttcagtgt cttattacca
    29101 ccgtatgcag gcagcttttg caggtttgga cttgcttcca caaactcagt ttgtggaagg
    29161 tcttcgtatg attaaggatg aggcagagat tgcagcgatt cgcaaggctt gttctatctc
    29221 agaccaagct ttccgcgatg cgcttgactt tatcaaacca ggaaaaactg aaattgagat
    29281 tgccaacttc cttgatttcc gcatgcgtga gttgggagca tctggcttat cttttgatac
    29341 gatcctagct agcggtatca attcttctaa accccatgcc catccaatgc acaaaccagt
    29401 ggagttggga gaagccatta ccatggactt cggctgtctc tatgaccact atgtcagtga
    29461 tatgacccgg actatctatc tagggcatgt tagcgatgag caggcagaga tttacaatac
    29521 ggttctaaaa gctaaccaag ccttgattga ccaagctaag gcaggcttag gtttccgtga
    29581 ctttgacaaa atccctcgtg atattatcat tgaggcaggt tatggtgact actttactca
    29641 cggcattggc cacggtattg gtctggatat ccatgaggaa ccctacttta gccagacttc
    29701 tacagaaact attaagacag gtatggcctt gaccgatgaa ccaggtatct atatcgaagg
    29761 caaatatggc gttcgtatcg aggatgatat cctgattaca gagacaggtt gtgaattatt
    29821 gaccctagct ccaaaagagt tgatagtcat ttagttgttt gtcaagaaaa aagtacgaaa
    29881 atgacgaaaa aagtcaaaaa aaattaaaaa taggtcgcaa gtcggatgtt ttttatggta
    29941 taatagacta aactgatagt aacatgtagc gaaaggggta ggtacatgat taaaatttat
    30001 acagtctcaa gttgtactag ctgtaaaaaa gcaaaaacct ggctcaatgc ccaccagtta
    30061 agttataaag aacaaaacct tggtaaagaa ggaattacga gagaagaatt actggatatt
    30121 ctaaccaaaa cagataacgg aatagccagc atcgtttcgt ctaaaaatcg ctatgccaaa
    30181 gcccttggag tggatattga agatttgagt gtcaatgaag ttctcaatct gattatggaa
    30241 acaccgagaa ttttaaagag cccaatcctt gtagatgaaa aacgcctgca agttggctac
    30301 aaggaagacg atattcgtgc cttcctacca cgctctgtcc gtaatgtaga aaatgcagaa
    30361 gcacgtttgc gtgcagctct ataaacatca aggctgggag cacttcccag tcttattcta
    30421 ttttaatttc aaaaagaaag aagaaagaaa tgaaaaaaat agttcttgtt agtctagctt
    30481 tcctttttgt cctggttggt tgcggacaga aaaaagaaac tggaccagct acaaaaacag
    30541 aaaaagatac gcttcagtcg gcattgccag ttattgaaaa tgctgagaag aatacagttg
    30601 taactaagac tttggtcttg cccaagtcag atgatggtag ccagcagaca caaacaatta
    30661 cttacaaaga caagactttt ttgagtctaa ctatccaaca aaaacgtcca gtctctgatg
    30721 agttgaagac ttatattgac caacatggag tggaagaaac tcaaaaagct cttcttgaag
    30781 cggaggagaa ggataagtct atcattgaag ctcgtaaatt ggcaggtttc aaacttgaaa
    30841 caaaactatt gagcgcaacg gaacttcaaa caacgactag ttttgatttt caagttctgg
    30901 atgtcaagaa ggcttcccag ttggaacatc tgaagaatat tggtttggaa aatcttttga
    30961 aaaatgaacc aagcaaatat atttcagata gattggcaaa tggcgcgaca gaacaataga
    31021 aaatccaaat aaatagactg cctgaattgt agaaggtaag gaattatgct ataatggtac
    31081 tattctaagg aaagagggtg ttagaatggg atttactgaa gaaacagtac gttttaaatt
    31141 ggacgattcc aataaaaaag aaattagcga aactttgaca gatgtttatg cttcgttgaa
    31201 cgataagggt tacaacccaa ttaaccaaat cgtaggttac gtattgagtg gagaccctgc
    31261 ctacgttcct cgttataata atgcacgaaa tcaaatccgt aagtatgagc gtgatgaaat
    31321 cgttgaggaa ttggttcgct actacctaaa aggacaagga gtcgatctat aacctatgag
    31381 aattatggga ttggacgtcg gttcaaaaac ggtaggggtg gcgattagcg atccgcttgg
    31441 ttttacagct caagggcttg aaatcatcca gataaatgaa gaacaaggcc aatttggttt
    31501 tgaccgcgtt aaggaattgg ttgatactta caaggtggaa cgatttgtag tgggcttgcc
    31561 taaaaacatg aacaatacaa gtggaccgcg cgtagaagct agtcaagcct acggagcaaa
    31621 gctagaagag ttttttggtt taccagtaga ctatcaggat gaacgcttga caacagtggc
    31681 tgctgagcgc atgttgattg aacaagcaga tatcagtcgc aataagcgca agaaagtcat
    31741 tgataagtta gcagctcagc tgattttaca aaattattta gatagaaaat tttaatataa
    31801 aggagaggct atgtcacacg atcataacca cgaccacgaa gaacgtgaac taatcacact
    31861 agtagatgag caaggaaatg aaaccttgtt tgaaatcctt ttgacaattg atggaaaaga
    31921 agaatttggt aaaaactatg ttcttctagt accagttaac gcagaagaag acgaagacgg
    31981 acaagttgaa atccaagctt actcattcat tgaaaatgaa gatggaacag aaggcgaatt
    32041 gcaaccaatc ccagaagact cagaagacga atggaacatg attgaagaag tcttcaacag
    32101 ctttatggag gagtaaaaac gtccggggga cgtttttagc cctgcgctag aaattagaaa
    32161 cgcaggtagt ctgggagact gtatcagccc aactccagaa atggggaaga gttggaacgt
    32221 ccagtgaaca tttttacccc aactcttaga aattgagaag agttggaaca tctagtggat
    32281 gtttttagcc catattcaca ttcatagtag ctagttatta gctaaccagg taagaggtcg
    32341 ggacgaaaat cctggccttg tttttattag taaccatact ttaatgcgat aattgattgg
    32401 acttttgtca aggagatgtg tatgtttgaa gtagaagaat ggctccatag tcggattggt
    32461 ttgaattttc gatcaggttt gggccgaatg cagcaagcgg tggatttgtt aggaaatcct
    32521 gagcagtctt accctattat ccacgtaaca gggactaatg ggaaaggatc taccattgct
    32581 tttatgaggg aattatttat ggggcatggc aaaaaagttg cgacctttac ctcccctcat
    32641 atcgtctcta tcaatgaccg aatctgcatt aatgggcaac ctatagcaga cgcagacttt
    32701 atccgtttga ctgatcaggt caaggagatg gagaaaacgc ttctgcaaac tcctgcccag
    32761 ttgtcctttt ttgaattgct gaccttagtt gcttttcttt attttaggga gcaagaggtg
    32821 gatttggttt tattagaagt gggaattggt ggcttacttg acacgaccaa tgtggtaact
    32881 ggagatcttg ctgtcatcac ctccattggg cttgaccatc aagaaacctt gggtgatagt
    32941 ctagaagcaa ttgcagagca gaaagctggt attttcaagg ctggtaagaa ggcagtgatt
    33001 gcgaaattgc ctccagaagc taggcttgtc tgtcagaaaa aagccgaatc tttagctgtt
    33061 aacctttatc aggcaggtca agatttttta atgctgaatg gtgatttttc aagctcttta
    33121 ctaaatcttt cacagctgaa cataggctta gaaggagtct atcagcagga gaatgcagcc
    33181 ttggcgttgc aaacttttct tctttttatg ggagaaggaa aggaagctgt tgatgaacag
    33241 gctgtaagaa aggccttgga acagacccat tgggctggtc gcttggagcg tattcgccca
    33301 cagatttact tggatggtgc tcataacctc cctgccttga ctcgcttggt tgagtttatc
    33361 aaagaaaaag agcaggaagg ctatcgacct caaatccttt ttggagcctt gaaacggaag
    33421 gattatcaag ggatgttagg ttacctgact gaaaaattgc ctcaggtgga actcaaggtg
    33481 accggctttg actatcaggg ggctttggac gaaagggatg tgacaggtta cgatatagtt
    33541 tcttcttacc gagaatttat cagcgatttt gaagaaagag cagatgctca ggatttgctg
    33601 ttcgttacag ggtctctcta ttttatctca gaagtacggg gctacctgct ggaccgtgag
    33661 cagataaatt gacccccttg tttgaacttg ttatactagg ggaattgctg gttagagaaa
    33721 atttctctaa attggtagca gaaaggaaat tcatcatgaa attaaaaaga ttcacacttt
    33781 ctcttgcttc tctagcaagt tttagtctct tagtagcttg ttcacaaaga gctcaacagg
    33841 ttcaacagcc tgttgctcag cagcaggtcc aacagcctgc tcaacagaat accaatactg
    33901 caaatgcagg aggtaaccaa aatcaagcgg ctccagtaca aaaccaacct gttgctcaac
    33961 cgaccgatat tgatgggact tatactggtc aggatgacgg agaccgtatc actttagtgg
    34021 taactggaac gactggtaca tggactgagc tcgaatctga cggggatcag aaagtcaaac
    34081 aggttacatt tgattcagca aatcaacgca tgattattgg cgatgatgtc aaaatttaca
    34141 ctgtaaacgg taatcaaatc gtcgtagatg atatggatag agacccatcg gaccaaatcg
    34201 ttttaactaa ataagactat gcaagtagaa agggctggat ttttcagcct ttttactttt
    34261 acctagaaaa taatcataaa tacttgcctt ctaccgaata cctgcgttat actagtatca
    34321 attacttgtt tttagcattc aaactatcaa ggaggggata tgaaatatag gaaatttcaa
    34381 ttattgatgt ccaagtatgg ctttagtctt tcgattatgc tacttgaact ttgtcttgtt
    34441 tttggtctct ttctttattt aggacgcatg gctcccattt tatggattac tgtcctcatt
    34501 ctactgagta tcatcacaat catttcgata gtcaaccgta atacgactcc tgagaataag
    34561 gtaacctggt tgttagtagc ctttgtgcca gtatttggtc ccttgctcta tctgatgttt
    34621 ggtgaaaggc gattgtccaa aaaagaaatc aaacaactga agaagctagg ctctatgcat
    34681 ttccaagaag caaatagcca gctactaaaa gagaaattaa aagaaagtga caaggcagct
    34741 tatggagtca tcaagtcctt attgagtatg gataccaatg ctgacatcta tgatcaaact
    34801 gcctctacat tttttcctaa cggagaagct atgtggaaaa agatggtaga agatcttaaa
    34861 aaggctgaga aatttatttt cttggaatat tacattatag aagaaggttt gatgtggaat
    34921 cgcatactag atatactaga gcaaaaggta gctcagggtg tagaggttaa gatgctctat
    34981 gatgatatcg gctgtatggc tactttaaca ggagattatg cacatcgact tcgtcagctg
    35041 ggcatcgagg cccataaatt caataaagtt attcctcgtt tgacagtggc ttataataac
    35101 agagatcata gaaaaatatt gattgttgat ggtcagatag cctatactgg tggggtcaat
    35161 ctggcagatg agtacattaa ccacgtcgag agatttggtt attggaagga tagtggaatt
    35221 cgcttagacg gactagcagt aaaagctctg acacgcttat ttttgaccac ttggtacatt
    35281 aatcgaggag aaattagtga ttttgatcaa tatcatttag aaaatcattc tatcccgagt
    35341 gacggtttaa ccattccata cggaagtgga cccaagccaa tttttcgagc gcaggtaggg
    35401 aaaaaagttt atcagagttt aatcaatcaa gcaacagaat cggtctatat tacgacacct
    35461 tatttgatta tagattatga tttaacagag acaatcaaaa atgcagctat gagaggggtc
    35521 gatgttcgaa ttatcacccc ttacatacca gataagaagt tcattcagtt agtcacgaga
    35581 ggagcttatc ccgaccttct ttctgctggt gttcggattt atgagtatag tccaggtttt
    35641 attcatagta agcagatgtt ggtagacgaa gattttgcgg tggtggggac aatcaatctc
    35701 gactaccgga gcttggtaca ccattatgaa aatgcagtct tactctataa aactccttct
    35761 ataagggaaa tcgcccgaga ttttcgaaat atatttgcag attctcagga agtctatcct
    35821 cattctatca aaacgagctg gtatcaaaag cttgtaaaag aaatcgccca gctattcgcc
    35881 cctatcttat aagaaatcta gaacttagga tacaaaccag acctattttt cttgtctttt
    35941 acgaatagaa agaaagagga ggggaattca tgctaactaa ggaagaagtg aatgatatga
    36001 ttgagttcaa acagacacat ttacaccgct ttcgggaaat tgaaaccttt gtgaaactat
    36061 gcaaaaaatc actcaaacag ccatcgcaag ctgacaatcc taggactttt tgatatacta
    36121 agacagataa attgaacagg agaaacgata tgagtgtgta tggtagagta gaagaagttc
    36181 ataaggagaa tcgtgaacct ctagaatacc aaatcgaaca agaatcgcat catcgtgaat
    36241 caagtcgtct tcctttggtg aaaattttac tatggagtac gcttgtaacg gggataactc
    36301 taggagtgcc gctattactc gacttaatga gtgcacaaga agtgcaggat ttttatgcag
    36361 gttgggcgct tcatcagaca gggaagattt acagcgacta ttatggaagt caaggtttgc
    36421 tttattattt gctgacttac gtgagtcagg gcggattttt ctttgccatc tttgagtggt
    36481 tagccttggt agcaggcgga tttttccttt ttagatcagc ggacaccttg acagagcaag
    36541 gagaccaagc tggacatctg gtgactattt tttacatgct agttacaggt cttgcttttg
    36601 gtggaggcta tgcgactctt ttagcgcttc ctttcttatt cgcagccttt agtttagttg
    36661 cggcttacct aagcaatcca agccatgata agggatttgt acggattggg ctagctttgg
    36721 caggcggatt tttctttgct cccttatcat cgctcctgtt tattgctgta gtgagtttag
    36781 gcttgttggt ctttaacctt gggcatagac gttttgtgca tgggttttat cagtttcttg
    36841 cagtggcttt aggtttttca cttgtctttt atccaactgc ctactatagt gctgcaacag
    36901 gaagttttgg ggatgcgatt agtggtattc gttatcctat tgacagtatt cgctttgatt
    36961 ttacttctaa aattttagag aatatgtttt tttatggctt gttgtccctt ggtttgggat
    37021 ttgtggtttg tatcttttta ggtctctttc aatccaaacc ctttaaacta tacgtcattt
    37081 cggttcctgc aagtcttgtg gtaattttag gtttgatttt acttttcttt tcacaagagc
    37141 ctctgcacgc ttcttatttg atggtcgtct tccctgtttt cctactttta ttggtaacca
    37201 atattaagag tcaacagagg gggcgtagtg ctagaagaag ccgaagagaa acgccagtta
    37261 gcctatggag tcgtttcttc aaaggaaatc tatatctgct agtttttggg tttgtctatc
    37321 ttttgtctgt tccttttttg atgaagtttg tcctttatcc agtaccttat caagaacgta
    37381 atcgtcttgc tgatttggta aaagaggaga caaatacgga agatgctatc tatgcatggg
    37441 atgatactgc gactctttat cgtaagagtg agcgcttgtc gccatcggcg attttgtccc
    37501 cgttgcacta tacagcaact gaggaaaatc gtaataagtt acttaatgac ttgaaagaaa
    37561 aacaacctaa ggtgattgtg gtaaatgaca aggtggtagt ctggtctgaa gtggaaacac
    37621 tcttaaaaga aaattaccaa caagtaaaga ctgattactc agagtttaaa gtctataaaa
    37681 ttaaataacc aaatcaatat cttgtgtatt tttaaaaatt ttaggatttt taacacaaga
    37741 tattgatttt tctttttaga gtggtataat actttttaga aagaacattt tagaaaagag
    37801 catgcgtatg attgcactag aagaaaaaat tacaattttg ccaactctct tcgtcgagaa
    37861 acgagatggg agacgtgttg tatttgatgt ggacaagatt gacaaggctc tccgcaaggc
    37921 ggctgacaag gttatggatg tgacacccct ggttgaaaaa cgcctcaatg atctgactga
    37981 gcgaattatt acagaaattc atagtcgctt tccacaggga attaagattt acgaaattca
    38041 aaatatcgta gaacatgaac tccttgaagc caaagaatat gcactggctg aggagtatat
    38101 tacttatcgg acacagaggg attttgagcg ctcaaaagcg acggatatca actttagtat
    38161 tcataaactt ctcaacaaag accagacagt tgtcaatgaa aatgctaata aagacagtga
    38221 tgtctttaac actcagcgtg atttgacagc agggattgtt gggaaatcaa tcggactgca
    38281 aatgcttcct aagcacgtag ccaatgccca ccaaaagggg gatatccact atcacgattt
    38341 ggactacagt ccctataccc ctatgaccaa ctgctgtttg attgatttta agggtatgtt
    38401 ggaaaatggt tttaagattg gaaatgcaga ggtagagagt cccaagtcta tccagactgc
    38461 gacagcacag atttctcaaa tcattgccaa cgttgcttct agccagtacg gtggctgttc
    38521 agctgaccgt atcgatgaaa ttttggcgcc ttatgcagag aagaattatc aaaaacatct
    38581 caaagatgca gaagagtggg tattgcctga aaaacgggaa gattacgctt ggaagaaagc
    38641 gcaaaaggac atctacgatg ccatgcaatc tcttgagtat gaaatcaata ctctcttcac
    38701 ttcaaatgga caaacacctt ttacttcgtt aggttttggt ctgggaacca gtcgttttga
    38761 acgagaaatt caaaaagcta ttttaaacat tcgcatcaag ggtcttggtt cagaacaccg
    38821 tacggctatc tttcctaaac ttatctttac gcttaaaaga ggcctcaact tagaggaagg
    38881 aactcccaac tatgacatca agcagttggc tctagagtgt gcaaccaagc ggatgtatcc
    38941 agacgtcttg tcttatgata agattgttga tttgacaggt tctttcaaag ttcctatggg
    39001 ctgccgttct ttccttcaag ggtggaagga tgaaaatggt gtagaagtca attcaggtcg
    39061 catgaatctg ggtgttgtga cggttaatct gcctcgtatt gctcttgagt ctgaaggtga
    39121 tatgaataag ttctgggaaa tcttcaacga gcgaatgaat atcgcagaag atgctcttgt
    39181 ttaccgtgtc gaacgcacta aagaggcgac accagcgaat gctcctattc tttatcagta
    39241 cggtgctttt ggccatcgtc taggtaaaga agaaagtgtt gaccagctct ttaagaatcg
    39301 tcgtgcgacc gtttcgctgg gctatatcgg cttgtatgaa gtagcgacag ttttctttgg
    39361 taacagctgg gaaagtaatc cagatgctaa ggaattcacg ctagacatca ttcacgatat
    39421 gaaacgccgt gtagaagagt ggtcagacca atatggctac catttctcta tctactcaac
    39481 accatccgaa agtctgacag accgtttctg ccgactagat atagacaagt ttggctctat
    39541 tcctgatatc acagacaagg aatactacac caactctttc cactacgatg ttcgtaaaaa
    39601 tccaacaccg tttgaaaaat tggactttga gaaagtctat ccagaagcag gtgcgtcagg
    39661 tggtttcatc cattattgtg agtatccagt ccttcagcaa aatccaaagg ccttggaagc
    39721 tgtctgggat tatgcttatg accgtgtagg ctatctaggc accaatactc cgattgaccg
    39781 ttgctacaag tgtgactttg aaggggattt tgaaccaact gagagagggt ttgcttgtcc
    39841 aaactgtggc aatagcgacc ctaaaacagt agatgtggtg aagcgaactt gtggctacct
    39901 aggtaatcct caagcaagac cgatggtcaa cgggcgtcac aaggaaatcg ctgcgcgtgt
    39961 caaacatatg aatggttcaa cgattaaaat agctgggcat caagtaacaa attagaaaga
    40021 aatgaaatgg gaaaatatca actagacgat aaggggcgcg cacaagtgac ccgttatcac
    40081 gagaaacact ctaaaggtgg agctggtaag aaagaacgct tgcttagctt cagagaacaa
    40141 tttttaaaca agaacaagaa aaaataaaag tgagagccag ctctcgcttt tctcatagtg
    40201 ggaggtaagg atggaattac gcagaccaag attagcggat aagaaagctg ttttagatat
    40261 gatgacagag tttgaaaaat ttcagtcgcc tcacgacggc ggtttctggg atacagagaa
    40321 ctttgtgtat gaagactggt tagaaagcaa tcaggaacag gaaatgggga ttaatctgcc
    40381 tgaaggatgg gttcctgcaa ttcagttagt ggctttttct gagaaaggtc aagcagttgg
    40441 atttcttaat ctccggttgc gcctcagtaa ctttctacta gaagaaggtg gccacattgg
    40501 ctactccatt cgtccatctg aaagaggcaa gggttatgca aaagagactc tccgtcaggg
    40561 cttgcaagtt gctaaggaaa agaacatcaa gaaagctctg gtgacctgta gcgtgaataa
    40621 tcctgctagc agagcagtca ttctagcaaa tggtggaata tttgaggatg ctcgcaatgg
    40681 agtcgagcgt tattggatag aggtagcgaa tgaataatcc aaaaccacaa gaatggaaaa
    40741 gcgaggaact tagtcaaggt cgtatcattg actacaaggc ctttaacttt gtggacggcg
    40801 aaggcgtgcg taactctctc tatgtatcag gctgtatgtt tcactgcgag ggatgttata
    40861 atgttgcgac ttggtctttt aatgctggca ttccctatac agcagaatta gaagagcaga
    40921 tcatggcaga tcttgctcag ccctatgttc aaggtttgac tttgttggga ggggagcctt
    40981 ttcttaatac tgggattctc ttgccacttg ttaagcggat tcggaaggaa ttgccagaca
    41041 aggacatctg gtcctggacc ggctacactt gggaagaaat gatgttggaa actccagata
    41101 aactggaatt cttgtcactg attgacattc ttgtcgatgg aagatatgat cgaactaaga
    41161 gaaatcttat gctccagttt cgaggttcat ctaaccaacg aattatcgat gtgcaaaaat
    41221 cgctcaaaag tgggcaagta gtgatttggg acaagctcaa tgacggaaaa gaaagctatg
    41281 aacaggtgaa gagagaatga agaaaaaaga cttagtagac caactagtct cagagatcga
    41341 gacggggaaa gtcaggacac tgggaatata cggtcatgga gcttcaggta aatcaacctt
    41401 tgcacaggaa ttgtaccaag ctttagattc tactacagta aatttgctag aaacagatcc
    41461 ctatatcacc tccggacgct atttggtagt acccaaggac gcgccgaatc aaaaggtgac
    41521 agccagtctg ccagtggcgc atgaactgga gagtttgcag agagatatcc ttgccttgca
    41581 ggcgggtatg gatgtcttga caattgaaga accttggaag gctagtgagg tcttgtctgg
    41641 agccaaacca attttgattg tcgaagggat gtctgttggt tttctaccca aggaactctt
    41701 tgaaaaaacc atctgtttct acacggatga ggagaccgaa ttaaagcgac gccttgctag
    41761 agatacgact gtgagaaatc gcgatgcatc ctttatattg gctagccatc agatgagacg
    41821 ggagcagtat ctgcgatact ataaagaaac tgagtctaag gcggatatct tagtggacca
    41881 atcagaagat aaatttgatg tcaagaggac ttaacttatg tatagaagaa atatagaaga
    41941 aaatccctaa ttttagaaag aaaaagtagg aaaacagttt catcccaaaa aaacgaaaaa
    42001 acctaacaaa tcccttgcaa tcgcagggga tttgtgttat tctattatgg tgctgtaaat
    42061 tacagcctta gttttgatgc aagaggttgc gacacgctcg gttgcattgc cacgcaacac
    42121 cgcgtcggtt ttcttgtgga gctagcctat tatcttaaat agacgaaaag gagaaaaaga
    42181 tggcaaacaa aaaaatccgt atccgtttga aagcttacga acaccgtacg cttgacacag
    42241 cggctgcaaa aatcgtagaa tcagctactc gtacaggtgc acaagttgcg ggtccaatcc
    42301 cacttccaac tgaacgtagc ctctacacaa tcattcgtgc gactcacaaa tacaaagact
    42361 ctcgcgaaca atttgaaatg cgtacacaca aacgtttgat cgatatcgtt aacccaactc
    42421 aaaaaacagt tgatgccttg atgaaattgg atcttccaag tggtgtaaac gtagaaatca
    42481 aactttaatc taaaatataa aagagcagag gctggtgttt caatctaatt gaacacgggc
    42541 taaactcggt gtgaaaaaga taaacttcct cgcgtctgct agacactgtg tcagtttcct
    42601 attttcactt tgagtttgac gccctttgta tcttagactt gagcataaaa aacgctcgtt
    42661 aaaaactttt tgaataaaaa atatagaaaa ggaactattt tctcatgaca aaaggaatct
    42721 tagggaaaaa agtgggaatg actcaaatct tcactgaagc tggcgaattg atccctgtaa
    42781 cagttattga agcaactcca aacgttgttc ttcaagttaa aactgttgaa acagacggat
    42841 acaacgctat ccaagttggt ttcgatgaca aacgcgaagt attgagcaac aaacctgcta
    42901 aaggacatgt agcgaaagct aacacggctc ctaagcgctt cattcgtgaa ttcaaaaacg
    42961 ttgaaggctt ggaagttggt gctgaaatta cagttgaaac attcgcagct ggagacgttg
    43021 ttgacgtaac tggtacttct aaaggtaaag gtttccaagg tgttatcaaa cgccacggac
    43081 aatcacgtgg accaatggct cacggttctc gttaccaccg tcgtccaggt tctatgggac
    43141 ctgttgcacc taaccgcgta ttcaaaggta aaaaccttgc agggcgtatg ggtggcgacc
    43201 gcgtaacaat tcaaaacctt gaagttgtac aagttgttcc agaaaagaac gttatcctta
    43261 tcaaaggtaa cgtaccaggt gctaagaaat ctcttatcac tatcaaatca gcagttaaag
    43321 ctggtaaata ataaagaaag gggaaatcag tcacaatggc aaacgtaaca ttatttgacc
    43381 aaactggtaa agaagctggc caagttgttc ttagcgatgc agtatttggt atcgaaccaa
    43441 atgaatcagt tgtgtttgat gtaatcatca gccaacgcgc aagccttcgt caaggaacac
    43501 acgctgttaa aaaccgctct gcagtatcag gtggtggacg caaaccatgg cgtcaaaaag
    43561 gaactggacg tgctcgtcaa ggttctatcc gctcaccaca atggcgtggt ggtggtgttg
    43621 tcttcggacc aactccacgt tcatacggct acaaacttcc acaaaaagtt cgtcgcctag
    43681 ctcttaaatc agtttactct gaaaaagttg ctgaaaacaa attcgtagct gtagacgctc
    43741 tttcatttac agctccaaaa actgctgaat ttgcaaaagt tcttgcagca ttgagcatcg
    43801 attctaaagt tcttgttatc cttgaagaag gaaatgaatt cgcagctctt tcagctcgta
    43861 accttccaaa cgtgaaagtt gcaactgcta caactgcaag tgttcttgac atcgcaaata
    43921 gcgacaaact tcttgtcaca caagcagcta tctctaaaat cgaggaggtt cttgcataat
    43981 gaatttgtat gatgttatca aaaaacctgt catcactgaa agctcaatgg ctcaacttga
    44041 agcagggaaa tatgtatttg aagttgacac tcgtgcacac aaacttttga tcaagcaagc
    44101 tgttgaagct gctttcgaag gtgttaaagt tgccaatgtt aacacaatca acgtaaaacc
    44161 aaaagctaaa cgtgttggac gttacactgg ttttactaac aaaactaaaa aagctatcat
    44221 cacacttaca gctgattcta aagcaatcga gttgtttgct gctgaagctg aataatctaa
    44281 ggaggaaata tcgtgggaat tcgtgtttat aaaccaacaa caaacggtcg ccgtaatatg
    44341 acttctttgg atttcgctga aatcacaaca agcactcctg aaaaatcatt gcttgttgca
    44401 ttgaagagca aggctggtcg taacaacaac ggtcgtatca cagttcgtca ccaaggtggt
    44461 ggacacaaac gtttctaccg tttggttgac ttcaaacgta ataaagacaa cgttgaagca
    44521 gttgttaaaa caatcgagta cgatccaaac cgttctgcaa acatcgctct tgtacactac
    44581 actgacggtg tgaaagcata catcatcgct ccaaaaggtc ttgaagtagg tcaacgtatc
    44641 gtttcaggtc cagaagcaga tatcaaagtc ggaaacgctc ttccacttgc taacatccca
    44701 gttggtactt tgattcacaa catcgagttg aaaccaggtc gtggtggtga attggtacgt
    44761 gctgctggtg catctgctca agtattgggt tctgaaggta aatatgttct tgttcgtctt
    44821 caatcaggtg aagttcgtat gattcttgga acttgccgtg ctacagttgg tgttgtcgga
    44881 aacgaacaac atggacttgt aaaccttggt aaagcaggac gtagccgttg gaaaggtatc
    44941 cgcccaacag ttcgtggttc tgtaatgaac cctaacgatc acccacacgg tggtggtgaa
    45001 ggtaaagcac cagttggtcg taaagcacca tctactccat ggggcaaacc tgctcttggt
    45061 cttaaaactc gtaacaagaa agcgaaatct gacaaactta tcgttcgtcg tcgcaacgag
    45121 aaataatatt aaactagtcg cttaagcaac tagtaaatcc gccagctcgg tagcgctcca
    45181 taggagtgca agccgctgtg gtacaacatt taaaggagaa aatataaaaa tgggacgcag
    45241 tcttaaaaaa ggacctttcg tcgatgagca tttgatgaaa aaagttgaag ctcaagctaa
    45301 cgacgaaaag aaaaaagtta ttaaaacttg gtcacgtcgt tcaacgatct tcccaagttt
    45361 cattggttac actattgcag tttatgacgg acgtaaacac gtacctgttt acatccaaga
    45421 agacatggta ggccacaaac ttggtgaatt tgcaccaact cgtacttaca aaggtcacgc
    45481 tgcagacgac aagaaaacac gtagaaaata aggagaacat aaatggcaga aattacttca
    45541 gctaaagcaa tggctcgtac agtacgtgtt tcacctcgta aatcacgtct tgttcttgat
    45601 aacatccgtg gtaaaagcgt agccgatgca atcgcaatct tgacattcac tccaaacaaa
    45661 gctgctgaaa tcatcttgaa agttttgaac tcagctgtag ctaacgctga aaacaacttt
    45721 ggtttggata aagctaactt ggtagtatct gaagcattcg caaacgaagg accaactatg
    45781 aaacgtttcc gtccacgtgc gaaaggttca gcttcaccaa tcaacaaacg tacagctcac
    45841 atcactgtag ctgttgcaga aaaataagga ggtaaaatcg tgggtcaaaa agtacatcca
    45901 attggtatgc gtgtcggcat catccgtgat tgggatgcca aatggtatgc tgaaaaagaa
    45961 tacgcggatt accttcatga agatcttgca atccgtaaat tcgttcaaaa agaacttgct
    46021 gacgcagcag tttcaactat tgaaatcgaa cgcgcagtaa acaaagttaa cgtttcactt
    46081 cacactgcta aaccaggtat ggttatcggt aaaggtggtg ctaacgttga tgcactccgt
    46141 gcaaaactta acaaattgac tggaaaacaa gtacacatca acatcatcga aatcaaacaa
    46201 cctgatttgg atgctcacct tgtaggtgaa ggaattgctc gtcaattgga gcaacgtgtt
    46261 gctttccgtc gtgcacaaaa acaagcaatc caacgtgcaa tgcgtgctgg agctaaagga
    46321 atcaaaactc aagtatcagg tcgtttgaac ggtgcagata tcgcccgtgc tgaaggatac
    46381 tctgaaggaa ctgttccgct tcacacactt cgtgcagata tcgattacgc ttgggaagaa
    46441 gcagatacta catacggtaa acttggtgtt aaagtatgga tctaccgtgg tgaagttctt
    46501 ccagctcgta aaaacactaa aggaggtaaa taaccaatgt tagtacctaa acgtgttaaa
    46561 caccgtcgtg agttccgtgg aaaaatgcgc ggtgaagcaa aaggtggaaa agaagtagca
    46621 ttcggtgaat acggtcttca agctacaact agccactgga tcactaaccg ccaaatcgaa
    46681 gctgctcgta tcgccatgac tcgttacatg aaacgtggtg gtaaagtttg gattaaaatc
    46741 ttcccacaca aatcatacac tgctaaagct atcggtgtgc gtatgggatc tggtaaaggg
    46801 gcacctgaag gttgggtagc accagttaaa cgtggtaaag tgatgttcga aatcgctggt
    46861 gtatctgaag agattgcacg tgaagcgctt cgacttgcta gccacaaatt gccagttaaa
    46921 tgtaaattcg taaaacgtga agcagaataa ggagaaggca tgaaacttaa tgaagtaaaa
    46981 gaatttgtta aagaacttcg tggtctttct caagaagaac tcgcgaagcg cgaaaacgaa
    47041 ttgaaaaaag aattgtttga acttcgtttc caagctgcta ctggtcaatt ggaacaaaca
    47101 gctcgcttga aagaagttaa aaaacaaatc gctcgtatca aaacagttca atctgaagcg
    47161 aaataataga ctagggaagg agaaatttca atggaacgca ataatcgtaa agttcttgtt
    47221 ggacgtgttg tatctgacaa aatggacaag acaatcacag ttgtagttga aacaaaacgt
    47281 aaccacccag tctatggtaa acgtattaac tactctaaaa aatacaaagc tcatgatgaa
    47341 aacaatgttg ccaaagaagg cgatatcgta cgtatcatgg aaactcgccc gctttcagct
    47401 acaaaacgtt tccgtcttgt agaagttgtt gaagaagcgg tcatcatcta atcaaacctg
    47461 aaaggagaaa actgaaatga ttcaaacaga aactcgtttg aaagtcgcag acaacagcgg
    47521 tgctcgcgaa atcttgacta tcaaagttct tggtggttca ggacgtaaat ttgcaaacat
    47581 cggtgatgtt atcgtggcat ctgtaaaaca agctactcct ggtggtgcgg ttaaaaaagg
    47641 tgacgttgtt aaagcagtta tcgttcgtac taaatcaggt gctcgtcgtg ctgatggttc
    47701 atacatcaaa tttgacgaaa acgcagcagt tatcatccgt gaagacaaaa ctcctcgcgg
    47761 aacacgtatc tttggcccag ttgcacgtga attgcgtgaa ggtggcttca tgaagatcgt
    47821 gtcacttgct ccagaagtac tttaattttt aggaacaaac tagtccccta gcttcaagct
    47881 agggtgccct tatgggcgta agaaaaatca aggagaaacc taatgtttgt aaaaaaaggc
    47941 gacaaagttc gcgtaatcgc tggtaaagat aagggaacag aagctgttgt ccttactgcc
    48001 cttccaaaag taaacaaagt tatcgttgaa ggtgttaaca ttgttaagaa acaccaacgt
    48061 ccaactaacg agcttcctca aggtggtatc atcgagaaag aagcagctat ccacgtatca
    48121 aacgttcaag ttttggacaa aaatggtgta gctggtcgtg ttggttacaa atttgtagac
    48181 ggtaaaaaag ttcgctacaa caaaaaatca ggcgaagtgc ttgattaatc acgaaggaaa
    48241 ggagaagtat aatggcaaat cgtttaaaag aaaaatatct taatgaagta gttcctgctt
    48301 tgacagaaca attcaactac tcatcagtga tggctgtgcc taaagtagat aagattgttt
    48361 tgaacatggg tgttggtgaa gctgtatcaa acgctaaaag ccttgaaaaa gctgctgaag
    48421 aattggcact tatctcaggt caaaaaccac ttatcactaa agctaaaaaa tcaatcgccg
    48481 gcttccgtct tcgtgaaggt gttgcgatcg gtgcaaaagt tacccttcgt ggtgaacgta
    48541 tgtacgaatt cttggataaa ttggtatcag tttcacttcc acgtgtacgt gacttccacg
    48601 gtgtcccaac aaaatcattt gatggacgcg ggaactacac acttggtgtg aaagaacaat
    48661 taatcttccc agaaatcaac ttcgatgacg ttgacaaaac tcgtggtctt gacatcgtta
    48721 tcgtaacaac tgctaacact gacgaagagt cacgtgcatt gcttacaggc cttggaatgc
    48781 cttttgcaaa ataatatagg aggtaaatct aatggctaaa aaatcaatgg tagctagaga
    48841 ggctaaacgc caaaaaattg ttgaccgtta tgctgaaaaa cgtgctgcat taaaggcggc
    48901 aggggactac gaaggtttat ctaaattacc tcgcaacgcc tcaccgactc gtttacataa
    48961 tcgttgtaga gttacggggc gcccacattc agtttaccgc aaatttggtc tgagtcgtat
    49021 cgcttttcgc gaacttgcgc ataaaggtca aattcctggt gtaacaaaag catcttggta
    49081 atttaagata tcaagggtgt caaaactcca agtaaaaata ggaaacttga cgaagaaact
    49141 aaagtttcta ggaaagttta tctttttcac acagagttta gcccgggttc aattgggctt
    49201 gccaatttga acccgagcta cagctttggc aaaaaagacc aatttgcttt ggagcattgc
    49261 ttctgcatta aattgtctat ttttgctcgt gctgttacgc tctttgtatc atgtattaac
    49321 tagcaagtgc aacttgcaaa ctactagtaa gaggagaaaa acaaaatggt tatgactgac
    49381 ccaatcgcag acttcctaac tcgtattcgt aatgctaacc aagctaaaca cgaagtactt
    49441 gaagtacctg catcaaacat caaaaaaggg attgctgaaa tccttaaacg cgaaggtttt
    49501 gtaaaaaacg ttgaaatcat cgaagatgac aaacaaggcg tcatccgtgt atttcttaaa
    49561 tacggaccaa atggtgagaa agttatcact aacttgaaac gtgtttctaa accaggactt
    49621 cgtgtctaca aaaaacgtga agaccttcca aaagttctta acggacttgg aattgccatc
    49681 ctttcaactt ctgaaggttt gcttactgat aaagaagcac gccaaaagaa tgttggtggt
    49741 gaggttatcg cttacgtttg gtaaaatcaa gatacaaagc tcgtaaagaa caaagcaaaa
    49801 ttaggaagtt ggagaagttt gtttacaaac aagccaactt atctattttg cacagttctt
    49861 agagcgtgtt cagttcagct cttgaactaa ataagtatct gaaccccgtg aaaactggcc
    49921 gttttggcct gacaatttaa caggagaaaa taaacatgtc acgtattggt aataaagtta
    49981 tcgtgttgcc tgctggtgtt gaactcgcta acaatgacaa cgttgtaact gtaaaaggac
    50041 ctaaaggaga acttactcgt gagttctcaa aagatattga aatccgtgtg gaaggtactg
    50101 aagtaactct tcaccgtcca aacgattcaa aagaaatgaa aactatccac ggaactactc
    50161 gtgccctttt gaacaacatg gttgttggtg tatcagaagg attcaagaaa gaacttgaaa
    50221 tgcgtggggt tggttaccgt gcacagcttc aaggatctaa acttgttttg gctgttggta
    50281 aatctcatcc agacgaagtt gaagctccag aaggaattac ttttgaactt ccaaacccaa
    50341 caacaatcgt tgttagcgga atttcaaaag aagtagttgg tcaaacagct gcttacgtac
    50401 gtagccttcg ttcaccagaa ccatataaag gtaaaggtat ccgttacgtt ggtgaattcg
    50461 ttcgccgcaa agaaggtaaa acaggtaaat aatgttgagt ggttgatcat caaccaccaa
    50521 cctattttcc aactttgtgc atagcacacg atttaaaact aaagaggtga aaactgtgat
    50581 ttcaaaacca gataaaaaca aactccgcca aaaacgccac cgtcgcgttc gcggaaaact
    50641 ctctggaact gctgatcgcc cacgtttgaa cgtattccgt tctaatacag gcatctacgc
    50701 tcaagtgatt gatgacgtag cgggtgtaac gctcgcaagt gcttcaactc ttgataaaga
    50761 agtttcaaaa ggaactaaaa ctgaacaagc cgttgctgtc ggtaaactcg ttgcagaacg
    50821 tgcaaacgct aaaggtattt cagaagtggt gttcgaccgc ggtggatatc tatatcacgg
    50881 acgtgtgaaa gctttggctg atgcagctcg tgaaaacgga ttgaaattct aataggagga
    50941 cactagaaaa tggcatttaa agacaatgca gttgaattag aagaacgcgt agttgctgtc
    51001 aaccgtgtta caaaagttgt taaaggtgga cgtcgtcttc gtttcgcagc tcttgttgtt
    51061 gttggtgacc acaatggtcg cgtaggattt ggtactggta aagctcaaga agttccagaa
    51121 gcaatccgta aagcagtaga tgatgctaag aaaaacttga tcgaagttcc tatggttgga
    51181 acaacaatcc cacacgaagt tctttcagaa ttcggtggag ctaaagtatt gttgaaacct
    51241 gctgtagaag gttctggagt tgccgctggt ggtgcagttc gtgccgttgt ggaattggca
    51301 ggtgtggcag atattacatc taaatcactt ggttctaaca ctccaatcaa cattgttcgt
    51361 gcaactgttg aaggtttgaa acaattgaaa cgcgctgaag aaattgctgc ccttcgtggt
    51421 atttcagttt ctgatttggc ataagaaagg ggataaaatg gctcaaatta aaattacttt
    51481 gactaagtct ccaatcggac gcattccatc acaacgtaaa actgttgtag cacttggact
    51541 tggcaaattg aacagctctg ttattaaaga agataacgct gctatccgtg gtatgatcac
    51601 agcagtatct cacttagtaa cagttgaaga agtaaactaa tgaagtttta ggggatgtgc
    51661 actgtaccat cccctaaaac tagatatagt catctatgat gacatcgtat aggcgagttg
    51721 atgggggaga caaccttttc tcccttatcg gcgctagcat tttacaaaag aggagaaaat
    51781 aaaaatgaaa cttcatgaat tgaaacctgc agaaggttct cgtaaagtac gtaaccgcgt
    51841 tggtcgtggt acttcatcag gtaacggtaa aacatctggt cgtggtcaaa aaggtcaaaa
    51901 agctcgtagc ggtggcggag ttcgccttgg ttttgaaggt ggacaaactc cattgttccg
    51961 tcgtcttcca aaacgtggat tcactaacat caacgctaaa gaatacgcaa ttgtgaacct
    52021 tgaccaattg aacgtctttg aagatggtgc tgaagtaact ccagttgttc ttatcgaagc
    52081 aggaattgtt aaagctgaaa agtcaggtat taaaattctt ggtaacggtg agttgactaa
    52141 gaaattgact gtgaaagcag ctaaattctc taaatcagct gaagaagcta tcactgctaa
    52201 aggtggttca gtagaagtca tctaagagag gtgacctatg ttttttaaat tattaagaga
    52261 agctcttaaa gtcaagcagg ttcgatcaaa aattttattt acaattttta tcgttttggt
    52321 ctttcgtatc ggaactagca ttacagttcc tggtgtgaat gccaatagct tgaatgcttt
    52381 aagtggatta tccttcttaa acatgttgag cttggtgtcg gggaatgccc taaaaaactt
    52441 ttcgattttt gccctaggag ttagtcccta tatcaccgct tctattgttg tccaactctt
    52501 gcaaatggat attttaccca agtttgtaga gtggggtaaa caaggggaag taggtcgaag
    52561 aaaattgaat caagctactc gttatattgc tctagttctc gcttttgtgc aatctatcgg
    52621 gattacagct ggttttaata ccttggctgg agctcaattg attaaaactg ctttaactcc
    52681 acaagttttt ctgacgattg gtatcatctt aacagctggt agtatgattg tcacttggct
    52741 gggtgagcaa attacagata agggatacgg aaatggtgtt tccatgatta tctttgccgg
    52801 gattgtttcc tcaattccag agatgattca gggcatctat gtggactact ttgtgaacgt
    52861 cccaagtagc cgtatcactt catctatcat tttcgtaatc attttgatta ttactgtatt
    52921 gttgattatt tactttacaa cttatgttca acaagcagaa tacaaaattc caatccaata
    52981 tactaaggtt gcacaaggtg ctccatctag ctcttacctt ccgttaaagg taaatcctgc
    53041 tggagttatc cctgttatct ttgccagttc gattactgca gcgcctgcgg ctattcttca
    53101 gtttttgagt gccacaggtc atgattgggc ttgggtaagg gtagcacaag agatgttggc
    53161 aactacttct ccaactggta ttgccatgta tgctttgttg attattctct ttacattctt
    53221 ctatacgttt gtacagatta atcctgaaaa agcagcagag agcctacaaa agagtggtgc
    53281 ctatatccat ggagttcgtc ctggtaaagg tacagaagaa tatatgtcta aacttcttcg
    53341 tcgtcttgca actgttggtt ccctcttcct tggtgtgatt tccattttac cgattgcagc
    53401 taaagatgta tttggtcttt ctgatgttgt tgcctttggt ggaacaagtc tcttgatcat
    53461 tatctctaca ggtatcgaag gaatcaagca attggaaggt tacctattga aacgtaagta
    53521 tgttggtttc atggacagaa cagaataaaa gtatttactg aatcagtaaa tactgaggga
    53581 gtggaggttt aaactctgac atttgtaaga gttggatctc ccctcttcta ttttgttttt
    53641 aaataggggt gaaaagactt tttgcttcta tttaaaaata aaataaggag atcaaatcat
    53701 gaatcttttg attatgggct tacctggtgc aggtaaggga actcaagcag caaaaatcgt
    53761 agaacaattc catgttgcac atatctcaac aggtgatatg ttccgcgctg caatggcaaa
    53821 tcaaactgaa atgggtgttc ttgctaagtc atatattgac aagggtgaat tggttcctga
    53881 cgaagttaca aatggaatcg taaaagaacg tctttcacaa gatgatatta aagaaacagg
    53941 attcttattg gatggttacc cacgtacaat tgaacaagct caggccttgg acaaaacatt
    54001 ggctgaactt ggcattgaac tagaaggtgt tatcaatatt gaagtgaacc ctaacagcct
    54061 tttggaacgt ttgagtggcc gtatcatcca ccgcgtaact ggagaaactt tccacaaggt
    54121 ctttaaccca ccagttgact ataaagaaga agattactac caacgtgaag atgataagcc
    54181 tgagacagta aaacgtcgtt tggatgttaa tattgctcaa ggagaaccaa tcattgctca
    54241 ctaccgtgcc aaaggtttgg ttcatgacat cgaaggtaat caagatatca atgatgtctt
    54301 ctcagatatt gaaaaagtat tgacaaattt gaaataaagc gtttttcaca cttgccaaaa
    54361 tccgctacaa atgttatact gagatagtct gacttataat tgttgtctct gtgtctagag
    54421 gcatcgaatc gaaatttatg gaggtgcttt tgcgtggcaa aagacgatgt gattgaagtt
    54481 gaaggcaaag tagttgatac aatgccgaat gcaatgttta cggttgaact tgaaaatgga
    54541 catcagattt tagcaacagt ttctggtaaa attcgtaaaa actatattcg tattttagcg
    54601 ggagatcgtg ttactgtcga aatgagtcca tatgacttga cacgtggacg tatcacttac
    54661 cgctttaaat aatcgaaaaa cttggaggga taagaaatga aagtaagacc atcggtcaaa
    54721 ccaatttgcg aatactgtaa agttattcgt cgtaatggtc gtgttatggt aatttgccca
    54781 gcaaatccaa aacacaaaca acgtcaagga taagatagaa aggagaaaac atggctcgta
    54841 ttgctggagt tgatattcca aatgacaaac gcgtagtaat ctcattgact tatgtttatg
    54901 gtatcggact tgcaacatct aagaaaattt tggctgctgc tggaatctca gaagatgttc
    54961 gtgtacgtga tcttacatca gatcaagaag atgctatccg tcgtgaagtg gatgcaatca
    55021 aagttgaagg tgaccttcgt cgtgaagtaa acttgaacat caaacgtttg atggaaatcg
    55081 gttcataccg tggtatccgt caccgtcgtg gacttcctgt ccgtggacaa aacactaaaa
    55141 acaacgctcg cactcgtaaa ggtaaagctg ttgcgattgc tggtaagaaa aaataatata
    55201 ggaggtaaaa gtcttggcta aaccaacacg taaacgtcgt gtgaaaaaga atatcgaatc
    55261 tggtattgct catattcacg ctacatttaa taacactatt gttatgatta ctgatgtgca
    55321 tggtaatgca attgcttggt catcagctgg tgctcttggt ttcaaaggtt ctcgtaaatc
    55381 tacaccattc gctgctcaaa tggcttctga agctgctgct aaatctgcac aagaacacgg
    55441 tcttaaatca gttgaagtta ctgtaaaagg tccaggttct ggtcgtgagt cagctattcg
    55501 tgcgcttgct gccgctggtc ttgaagtaac agcaattcgt gatgtgactc cagtgccaca
    55561 caatggtgct cgtcctccaa aacgtcgccg tgtataatca tcgcattaca ctgcttttcg
    55621 tttaagaggg agtaactaaa tgatcgagtt tgaaaaacca aatataacaa aaattgatga
    55681 aaataaagat tatggcaagt ttgtaatcga accacttgaa cgtggctacg gtacaactct
    55741 tggtaactct cttcgtcgtg tacttctagc ttctctacca ggagcagctg tgacatctat
    55801 caacattgat ggtgtgttac atgagtttga cacagttcca ggtgttcgtg aagacgtgat
    55861 gcaaatcatt ctgaacatta aaggaattgc agtgaaatcg tacgttgaag acgaaaaaat
    55921 catcgaactg gatgttgaag gtcctgctga agtaacagct ggtgacattt tgacagatag
    55981 cgatattgaa attgtaaatc cagatcatta tctctttaca atcggtgaag gttcttctct
    56041 aaaagcgact atgactgtta acagtggtcg tggatatgta cctgctgatg aaaataaaaa
    56101 ggataatgca ccagttggaa cacttgctgt agattctatt tatacaccag ttacaaaagt
    56161 caactatcaa gtggaacctg ctcgtgtagg tagcaatgat ggtttcgaca aattaaccct
    56221 tgaaatcttg acaaatggaa caattattcc agaagatgct ttagggcttt cagcacgtat
    56281 tttgacagaa catcttgatt tgtttacaaa tcttactgag attgctaagt caactgaagt
    56341 gatgaaagaa gctgatactg aatctgacga ccgtatttta gatcgtacga ttgaggaact
    56401 ggacttgtct gtgcgttcat acaactgttt aaaacgtgcc ggtatcaata ctgtgcatga
    56461 tttgacagaa aaatctgaag cagagatgat gaaagtacga aatcttggac gcaagagttt
    56521 ggaagaagtg aaactcaaac tcattgattt gggtcttgga ttaaaagata aataaaggag
    56581 gaatacatgg cttaccgtaa actaggacgc actagctcac aacgtaaagc aatgcttcgc
    56641 gatttgacaa ctgacctttt gatcaacgaa tcaatcgtga caactgaagc tcgtgctaaa
    56701 gaaatccgta aaactgttga aaaaatgatt actctaggta aacgtggtga tttgcatgca
    56761 cgtcgtcaag cagctgcttt cgtacgtaat gaaatcgcat ctgaaaacta tgatgaagca
    56821 actgataagt acacttctac tacagcactt caaaaattgt tctcagaaat cgcacctcgt
    56881 tatgctgaac gtaacggtgg atacactcgt atccttaaaa ctgaaccacg tcgtggtgat
    56941 gcagcgccaa tggcgatcat cgaattagta taaaatcatc aattttgttg agtgttatga
    57001 tgatggagtc ttgtgctctt agtctagctc tggtctaccg ctaggatttc ggtcctagcg
    57061 ggaacactca tcataagttg ggatagtaga cgcttgttta cgaaattgtt tttttcttaa
    57121 gaacaacttc gtaagcaggc gtttttgagt attttcgtta gaattatgct atactatttg
    57181 aaaagaatcc tgtttaatgt taaggtttct tattttaaga agaattggag tttgcttatg
    57241 aaagcgatta taactgttgt tggtaaagat aaatctggaa ttgttgcagg tgtttctggt
    57301 aaaattgcag aattaggatt gaatattgac gatatctctc aaactgtctt ggatgaatat
    57361 tttacgatga tggctattgt atctagtgat gaaaagcaag attttaccta tcttcgtaat
    57421 gaatttgaag cttttgggca aactttgaat gtaaaaatca atattcagag tgcagcgatt
    57481 ttcgaagcta tgtataatat ctaggaggtt atcatggata ttagacaagt tactgaaacc
    57541 atcgccatga ttgaggagca aaatttcgat atcagaacca ttaccatggg gatttctctt
    57601 ttggactgta tcgatccaga tatcaatcgt gctgcggaga aaatctatca aaaaattacg
    57661 acaaaggcgg ctaatttagt agctgttggt gatgaaattg cggctgagtt gggaattcct
    57721 atcgttaata agcgtgtatc ggtgacacct atttctctga ttggggcagc gacagatgcg
    57781 acggactacg tggttctggc aaaagcgctt gataaggctg cgaaagagat tggtgtggac
    57841 tttattggtg gtttttctgc cttagtacaa aaaggttatc aaaagggaga tgagattctc
    57901 atcaattcca ttcctcgcgc tttggctgag acggataagg tctgctcgtc agtcaatatc
    57961 ggctcaacca agtctggtat taatatgacg gctgtggcag atatgggacg aattatcaag
    58021 gaaacagcaa atctttcaga tatgggagtg gccaagttgg ttgtattcgc taatgctgtt
    58081 gaggacaatc catttatggc gggtgccttt catggtgttg gggaagcaga tgttatcatc
    58141 aatgtcggag tttctggtcc tggtgttgtg aaacgtgctt tggaaaaagt tcgtggacag
    58201 agctttgatg tagtagccga aacagttaag aaaactgcct ttaaaatcac tcgtatcggt
    58261 caattggttg gtcaaatggc cagtgagaga ctgggtgtgg agtttggtat tgtggacttg
    58321 agtttggcac caacccctgc ggttggagac tctgtggcac gtgtccttga ggaaatgggg
    58381 ctagaaacag ttggcacgca tggaacgacg gctgccttgg ccctcttgaa cgaccaagtt
    58441 aaaaagggtg gagtgatggc ctgtaaccag gtcggtggtt tatctggtgc ctttatccct
    58501 gtttctgagg atgaaggaat gattgctgca gtgcaaaatg gctctcttaa tttagaaaaa
    58561 ctagaagcta tgacggctat ctgttctgtt ggattggata tgattgccat cccagaagat
    58621 acgcctgctg aaactattgc ggctatgatt gcggatgaag cagcaatcgg tgttatcaac
    58681 atgaaaacaa cagctgttcg tatcattccc aaaggaaaag aaggcgatat gattgagttt
    58741 ggtggtctat taggaactgc acccgttatg agggttaatg gggcttcgtc tgtcgacttc
    58801 atctctcgcg gtggacaaat cccagcacca attcatagtt ttaaaaatta agaaaatagg
    58861 agaaatttta agttctattt aagattagat gtgtatacta taatcattaa ataaagacct
    58921 cctaatatta tttgaaacag ataacactga attagtttga atttgatttt catctaatat
    58981 ctttatttaa tgaactccta aactttttca taataatctc cttcaaaagt cgcctgtatg
    59041 ggtggctttt attttatcat tcatgatata atagaagcaa acggaggacg gaaaatggta
    59101 aaagtacgat tgtatttggt acgtcatggc aagaccatgt ttaacacgat tggtcgcgcg
    59161 caaggttgga gcgatactcc cttaactgct gaaggtgaac gagggattca agagttagga
    59221 atcggtttgc gagaatctga tctacagttt gagcgcgctt attcgagtga ttctggtcgt
    59281 accattcaga ccatgggaat tatccttgaa gaacttggct tgcaggggaa aatcccttat
    59341 cgcatggaca agcgtatcag agaatggtgt ttcggtagtt ttgatggagc ctatgatggc
    59401 gatcttttca tgggcattat tcctcgtatc tttaatgtgg accacgttca ccaattgtct
    59461 tatgctgaac tggctgaggg cttggtagag gtcgatacag ctggttgggc tgaaggctgg
    59521 gaaaaactca gtggtcgaat caaggaaggc tttgaaatga ttgcaaaaga aatggaagat
    59581 caaggtggag gtaacgccct tgttgtcagc catggaatga ctattggaac cattgtttat
    59641 ctgattaatg gcatgcatcc gcatggtcta gataatggta gcgtgacgat tcttgaatat
    59701 gaggacggtc agtttagggt tgaagttgtc ggtgaccgta gttaccgaga gctaggacgt
    59761 gagaagatgg aagaaggctc tatttaatca gtctagactt gcttgccatg agctagggat
    59821 ttgataagaa tatcaagata agaaaaaaca gccgagggta ctcctttcgg ctgtttttga
    59881 tgtggaaaac taaagtgtaa tgctattgct tttagagatt ttcataaaca agagcaagga
    59941 acctactgtt agaacagtca ggatagttga caaggctgcg gctacaccgt aatttcctct
    60001 gagaacctct gtataaatag ctacagtcat tgttcttgtt ttgacattgt agaggaggat
    60061 agaagtagag agttctgaaa tcagtgtgac ccaagatagg atggctccag aaataatatc
    60121 cgatagcatc attggagttg taatcttagc aaagatattg agacgactac ttcctaagct
    60181 ttcagcagct tcttcaatac ttggtgctat ttgttgtaag ctagcaacag atgagcgaat
    60241 agtataaggt aattttctgg cagatagaga cataatcaag atgaaagcag tccctgtaat
    60301 cataagaaat ccacttccaa atagaccaga gaaatgaagg caatccctag aacggttcct
    60361 ggtacaatat aaggtaccat actgaggctg tcaattaagt ttgtaaacaa attccgtttt
    60421 ctaacggcta ggtaggagat aaatgtcgta aatagaacaa ctagaactaa ggcaatcaaa
    60481 gggatacgaa tggtattgaa aatagcagat cccatacgat tgaaagctag cttgtaactg
    60541 tttggagaat aacctttaac aaataccata cctgatgttt ttaggaaaga ggtataaatt
    60601 aagtagattt gaggtaaaac agagataaag ataattccgt agactgttgc ataaatggca
    60661 gccatttttc cttttgtagt ttttttaggc tcaattggat ggagcagatt catgctgaaa
    60721 ctgtagcggt ttgcaatgtg tttttggata aggaaaattg ccaaggcaat gataatcgcc
    60781 ataattgcaa aagcagaatt tcctccaacc tcgctaataa attgggtata aatcaggaca
    60841 gggaaagtcc gatacccttc gccaatcaac ataggcgttc caaagtctga gaatgctctc
    60901 ataaatacaa gcaaggagct gctagtaagg ttggaactag gagaggtaaa acaaccgtta
    60961 cgataggttt aaatccgaag gaccccatgc tttcagctgc ttcaagtaga gaattgtcaa
    61021 tactgttcat tgttccagca acatatagaa ataccagtgg gaatagttgc agtgtaaaga
    61081 caagtacaat tcctttgaat caataaatat cgatagctgg aagataaagg gcatttgtca
    61141 aaaatttagt gatgacctca tttcgtccca gcaagagaat ccaggagtag gctcctacga
    61201 aaggagctga catggaagca atgataatca atatttgtag aaatttcttc cccttgaagt
    61261 catacataga gaagagataa gctaataggg ttcctacaac taaggaagtg atagtagcgg
    61321 taatggaaac cttgaaactg ttgactagtg tctcagagta gtaggcttta ctaaagaaag
    61381 tgacaaaatt agctagtgag aattgtcctt catgtataag tgcttgcttg agcacggtaa
    61441 cgataggata aacgagaaag ataggatagg taagaaagag gaagaaagag gaagctgtcc
    61501 aaatatttag ttttttacgt tccatggttg actcctttta tcaggttttg ggaaccatct
    61561 gcagaaaaga tgtttaattt ttgcgtattg attcgtagac gaatacgatt gcctttttgt
    61621 agatcttctt caaaagttga ttcttcacta acttgaattt ttgaggcaaa acctgtctca
    61681 atgaaataat ccgtatttag tccaagatag acgctatctc taatagttcc ttcaatatct
    61741 ccagattcat ctttgataaa ctcttcggga cgaatgctta catgaatagc ttgctcctca
    61801 acctgatcaa gagctggcat tcgaagggca tagccatctg aaaagacgat ataagcgccg
    61861 tcgctccgtt tttcaagatt ggcagggata atatttgtgc gtccgataaa ggttgccaca
    61921 aactcattag ctggtttatg atagagttct tttggtcggc cgatttgttg gatcacccca
    61981 tctttcataa cagcaatttg gtctgaaata gccatggctt cttcttggtc gtgggttaca
    62041 taaacagttg taattcccac ttcgtgttgg atttctcgga tggcttgacg catatccaag
    62101 cgaagtttgg cctccagatt actaagtggc tcgtccatga ggagaacact tggattaacc
    62161 gctaaggcgc atgccaaggt gacacgttgt tgttgtccac cactgagttt atcgggcttt
    62221 cgatccgcat attgagcaat ttgcatgagt tcaagatact tgttggtctg ttgaatcaat
    62281 tcttcttttg cataagacca aaagcaacgt tgtctcggac agtcaaatgt gggaaaatag
    62341 cgtagttttg gaaaaccatc ccgatattgc gtttgctggg ttccatatta ttgatttttg
    62401 tatcatcgaa gtaaaattct ccatctttga tactgttgaa acctgcaatc atacgaagaa
    62461 gggtcgtttt cccacatcct gaagctccaa gaagggtaaa gagacttcct tttggaattg
    62521 taatgttcaa attctcaata acagggacat cgtggtagat ttttttggcg ttaataattt
    62581 tgatctcact catagtgaac ctcttttact gtttagattg gatatctgta aagacttcgt
    62641 tgtatttctt aacgatatct gatttattct tgatgacata atcataatct tcagtgagtg
    62701 ttttgatttt gtcaattggt ttcatgtttt cgcttgtttt agcattttta cgaacaggac
    62761 ggttagtagt ggttgtacca agtgtatctt gtacttcttg agagataata aaatcgataa
    62821 atttcttggc attttccata tttttagatt ttttaacgat agcagcacta gcaggtagga
    62881 agacggttcc ttcttttgga tagactacct taatgttagc tccgtcattt aagagtttaa
    62941 ctgctggatc ttcataagag agaccaacag ccatttctcc atcagcgact actttataga
    63001 cactagatga acttgaaccg attttaccat caataagtgt gaaaagatct tttacataag
    63061 accaagcctt atcatctttg taaccacctt gagcttgtag catatttgtt aattgagcaa
    63121 aggcgctaga agagtttgct gggtcagcag ttgcgatttt tccttttagt tcaggtttga
    63181 aaagatcgtt atatccttcg atgttcatgc ctttagttaa atcagggttg acgattaaaa
    63241 cactaccatc tagtgtataa ggagtagagt agccagttgt gttttgatat tctttgataa
    63301 cattatcatt ttcttttgaa gtatagtttt caaagagttc tccgtgggta gtatattgtg
    63361 tataagaacc accaaagata acatcagcta caggaacttc tttttctgac tctagttttt
    63421 tgaaaagttc tccagtacca gcttgaatca gttctacttt gataccatat ttttcttcaa
    63481 aggcaggaat agttgctcca attaagccct ctgagtttgg tgaataaacg actagcgaac
    63541 cgccgtctcc tttatcagat gaactgtcat cggcagattc attagaagaa caagcagcat
    63601 aatacatcca tttctttttc atgatggata cctccgttgt gttatttaag tttattttaa
    63661 aacaatgtaa gcgtttttaa aacatacaat tctattctat agtgtattga atctataaca
    63721 gtacactttg actgctaaaa tatttctata aattaatttg actttcctga tagagatgtt
    63781 cacatcttat ttcaattcac tatattagag taaaattctc tacaaaaaga agaatagcct
    63841 attttactat tcttctgagt gatttcaatt cctttgggga aatatggaga tactttttaa
    63901 atcctgacaa atggttgttt ctttttctaa atcggtgata ctgtatcgga gaatgcgcgt
    63961 gaggtcacaa aggctgcgat agagcttcta tggagaattt ctttttggag agatttttta
    64021 aaggaatgag acatccgcta cctccttgga aggttttttt gtgataagta tagcagttta
    64081 aaaattctag agcaaggtaa aatagaaaag gtttggctaa aattttttag ctaaaccttt
    64141 tgaaaagtta agtatgtatt atagatgctt gttatctgca aatagctaga gcatttcaag
    64201 gaaataaact agaaataaca attaatatgg tggttcagaa ataccttttg ataatcaata
    64261 agatcttcag gatgaagtgc gttgattcca tccatttcat atttccgatt taataaacga
    64321 tatttgtttt caccaaattg atgaaaaggg agtagttgaa cttggtcgat atttaatgag
    64381 ttaaatagag tagcgaattt ttctgcatcc tctaaactat tgttaaaatt aggaataact
    64441 gggattctta aaacgatagt tttattttgt gaaaaagcat aatgaatgtt tttaataatc
    64501 atttgattaa aaaccccagt cactttttta tgttttatag aattataatg ttttaggtct
    64561 gtgtagataa aatccacata ttgaattaaa tcaataaatt tttcatgatc aacaaaggca
    64621 gtagtttcaa tggcagtgtg tatgtgatgt tctttagctg attttaagat ggctttagca
    64681 aattcaaact gagcaaatat ttcacctcct gataaagtta aacctccacc ggattcttcg
    64741 taaaattctt tgtcttttaa tacctctgta ataatttctt ctacagtctt ttcttcaccg
    64801 actaaggtga atttctctcg ttgagcatct ttcatttttt caggtttcat tctttgagat
    64861 tcaggattag aacaccatgg acagcgcaga ggacatcctt ttaaaaaaac agttgtacga
    64921 atacccgggc cgtcatgaat tgaaaagtgt tgaatattaa aaataattcc tttagatatt
    64981 tccataagag ttcctcctct tcataagtct atcctatcac aaaaacgaaa gaaaaacaat
    65041 tacgaacgaa aggttaattt attgtttttt gctttttatt ttggtagaat aaaacggagg
    65101 tgtaaaatga aaagattgga acaaattatt aaattagtat cagaatatga aaagatcgac
    65161 gttaatacat tatcggaaaa attaaatgta tcgaaagtaa cgattagaaa agatttagat
    65221 aaattagagt caaaaggttt attacacaga gagcatggat atgctgtatt aaatagtgga
    65281 gatgacttaa atgtacgttt gtcaattaat tatgaaatta agagaaaaat tgttcaggaa
    65341 gcagtaaaat tggtgtcaga taatgaaaca ataatgatag aatctggatc gacctgtgct
    65401 ttacttgctg aggaaatttg caagcaaaaa agaaatgtta cgattgtaac aaattcattt
    65461 tttatagcaa attttgtgag agcttatgat tcatgtcgta ttattgttct tggtggagag
    65521 tttcagaagg attcacaggt tactgtggga cctttattaa aagaaatgat acagactttt
    65581 catgtgcatc aagcttttgt tgggacagat ggttacgata aagagatggg ctttacagga
    65641 aaagatttaa tgcgcagtga ggtagttcaa tatatttcag cagcgtcgga taaagtcatt
    65701 gtactaactg actcaagtaa atttgataaa aggggtacag taagaagatt tgctttaagt
    65761 caagtctatg aagtaataac agacgaaaaa ctttctaaac aaaatatagc tacattagaa
    65821 aatgctggga taatggttaa ggtagtttcg taagaggtta agtgtatgaa tcaagatagg
    65881 aataaactgc tctctaaaat tgcttatctg tattatattg aaaacttaaa tcagtcacaa
    65941 atagcagcaa aattaggaat ttatagaacc tctattagta gaatgttaac agaagcaagg
    66001 aatgcaggaa ttgttaaaat tgaaatagag aattttgata ccaatatgtt taagttggaa
    66061 aattatgtaa aagaaaaata tggtctggaa agtttagaaa ttattccaaa tgaatttgat
    66121 gataatccaa caattttatc tgaaagaatt tctcaagttg cagcaggtgt ccttaggaat
    66181 ctaattgatg ataatatgaa aattggcttt tcttggggga aaagtttaag taatttagta
    66241 gatttaattc acagtaaaag tgtccgaaat gttcacttct atcctctagc aggtggtcct
    66301 agtcacatac acgctaaata ccatgtgaat acactgattt atgaaatgtc tagaaaattt
    66361 catggagagt gtacatttat gaatgcaacg attgtgcaag aaaataaatt gttagcagat
    66421 ggtattttgc aatcaagata ttttgaaaat ttgaaaaata gttggaaaga tttagatata
    66481 gctgtagtcg gaattggtga ttttagcaat aaaggaaagc atcaatggtt agacatgctt
    66541 acagaggatg actttaaaga attgaccaaa gttaaaactg taggagaaat ttgttgtcga
    66601 ttttttgatt caaaaggtaa agaagtctat gaaaacttac aggaaagaac gatagcaatc
    66661 tctttggaag atttaaaaaa tattcctcaa agtttagctg ttgcttacgg tgatacgaaa
    66721 gtatcttcga ttctttctgt cttgcgtgct aatttagtaa atcatttgat tacagacaaa
    66781 aatacaattt taaaagtttt ggaagaagat ggggatttga cttttagaga gattctaggt
    66841 gagtgaaaat gatagactga ttcagtttat cgtttttctt tttagttgat tgcacatttg
    66901 tgcttatata aacaaaaata gtttatctgt tgtttttgga ttgacaactt tattatgtag
    66961 ttgtattcta tagttacaaa agaaaatttt aaaatttcaa atgaaaaaag ctttttacat
    67021 agtgaaatga ggaggaattt atggaaatta ttgttccaga tcaaattatc atgggtttaa
    67081 ttttatatgc tggcgatgcg aaacaacata tttataaagc attagattac ataaagaacg
    67141 gtacatgtga acgatgtgaa gaagaaatcc agttagctga tgcagcctta ttagaagctc
    67201 ataatctaca aacaaaattc ttggcacagg aagcgtctgg tacaaagaca gaaattacag
    67261 ctctctttgt tcattcacaa gatcatctca tgactagtat gacggagatt aatttaatca
    67321 aagaaattat tagtttgaga aaagaacttc ataaaaaata atactagagt attatcattg
    67381 ttattaacat agaggaggaa aacataatgg tgaagattgg tttgttttgt gcagcaggtt
    67441 tttctactgg tatgcttgta aataatatga aaattgcagc gcaatctagt ggagttgagg
    67501 cagaaataga ggcgttttct cagtctaaat tagcggatta tgcgccaaat atagatgttg
    67561 cactattggg tccacaagtt gcttatacat tagataaatc aaaagaaatt tgtgataagt
    67621 gtgatgttcc gatagctgtt attccgatga tggactatgg tatgttagat gggaaaaaag
    67681 tattagattt ggccctatct ttgattagtg ggtaagaaaa ggagatttat tatgtcaaag
    67741 atggatgttc agaaaatcat tgcaccgatg atgaagtttg tgaatatgcg tggcattata
    67801 gctctaaaag atgggatgtt agcaattttg ccattgacag tagttggtag tttgttcttg
    67861 attatgggac aattgccgtt cgaaggatta aataagagca ttgctagtgt ttttggagct
    67921 aattggacag agccgtttat gcaagtatat tcaggaactt ttgctattat gggtctaatt
    67981 tcttgttttt caattgccta ttcttatgct aagaatagcg gagtagaggc tttaccagct
    68041 ggagttctat ctgtatctgc attctttatt ttgctaagat catcttatat ccctaaacaa
    68101 ggtgaggcga ttggggacgc tattagtaaa gtttggtttg gaggccaagg aattatcggt
    68161 gctatcatta taggtttggt agtaggaagt atttatacct tctttataaa gagaaaaatt
    68221 gttattaaga tgccagaaca agttccacaa gctattgcca aacagtttga agcaatgatt
    68281 ccagcatttg taattttctt atcttctatg attgtatata ttttagcgaa gtcattgact
    68341 aatggcggaa cattcataga aatgatttat tctgctattc aagttccgtt gcaaggttta
    68401 actggatctt tgtatggtgc tattggaatt gcattcttta tatcattttt gtggtggttt
    68461 ggtgttcatg ggcaatcggt agtaaatgga gtagtgacag ctctgctttt atctaatctt
    68521 gatgctaata aagctatgtt agcctctggt aatctatcat tagaaaatgg tgcacatatt
    68581 gttactcaac aatttttaga ttcattttta attctatcag gttcagggat tacgtttggt
    68641 cttgtagttg ccatgctttt tgcagcaaaa tcaaaacaat accaagcctt aggaaaagtt
    68701 gcagcttttc cagcaatatt taacgtaaat gagccagttg tatttggatt tccgattgtc
    68761 atgaatccag ttatgtttgt acctttcatt cttgttcctg tacttgcagc tgtgatagta
    68821 tatggagcta ttgcaacagg tttcatgcag ccattctcag gggtaacatt gccttggagt
    68881 acaccagcta ttctatcagg atttttggtg ggtggatggc aaggtgttgt gactcagtta
    68941 ttagtattgg tgatatctac agtggtttac tttccattct ttaagataca agatcgttta
    69001 gcttaccaaa atgaaatcaa acaatcttag aggtatttgt gtgttactgt taaactcaca
    69061 catttgtgct aaaaattaga gagttaaaat ttttctagtt aaaagcttga aaatttctat
    69121 aaaaatcggt attatatttt cgaaagaaat aaaaatattt tcgaaagaaa ggtgcttacg
    69181 atggtaaata cagaagtagc aagaacaaca atcaagacag aatattttgg cagccttact
    69241 gaaaggatga acaaatatcg agaagatgtt ttaaataaaa aaccttatat tgatgctgag
    69301 agagcagttc tagcaacacg cgcctatgaa cgatacaagg aacaacctaa tgtcctaaaa
    69361 cgtgcatata tgctgaaaga aattttggaa aatatgtcta tctatattga agaagaatct
    69421 atgattgcgg gaaatcaagc ttcttccaat aaagatgctc ctatttttcc ggaatatacg
    69481 ctagaatttg ttctcaatga gttggatctt tttgaaaagc gtgatggaga tgttttctat
    69541 attacagaag aaacaaaaga acaacttaga agtattgctc cgttttggga aaataataat
    69601 ttacgtgcta gagctggtgc cttattacct gaagaagtgt ctgtttatat ggaaacagga
    69661 ttcttcggta tggaaggtaa gatgaattct ggagatgctc acttagcagt taactatcag
    69721 aaacttttgc aatttggttt aagaggtttt gaagagcggg ctcgtaaagc aaaagtagct
    69781 ctagatttaa cagatccagc aagtattgat aaatatcatt tttacgactc tatatttatc
    69841 gtaatcgatg ctattaaagt atatgcaaag cgctttgttg ctcttgctaa aagtttagcc
    69901 gaaaatgcaa atcctaaacg taagaaagaa ttacttgaga ttgcagatat ttgctctaga
    69961 gtcccatatg aaccggcaac tacttttgca gaagctattc aatcagtttg gtttattcaa
    70021 tgtattttac aaattgaatc taatggccac tctctttcat atggccgttt tgatcaatat
    70081 atgtatccat atatgaaggc tgatttagaa agtggtaaag aaacagaaga tagcattgtt
    70141 gaacgtctga caaatctttg gattaagaca attacaatta ataaggttcg cagtcaatca
    70201 catacatttt cttcagcagg aagtccttta tatcaaaatg ttacaattgg tggacagact
    70261 cgagataaga aggatgctgt taacccatta tcttatttgg tattaaaatc agttgcacaa
    70321 acccatctac cgcaacctaa tctaactgta cgttaccatg caggtttaga tgctcgtttc
    70381 atgaatgagt gtattgaagt gatgaaactt ggttttggta tgcctgcatt taataatgat
    70441 gagattatta ttccttcttt tattgcaaaa ggagtattgg aagatgatgc ttatgattac
    70501 agtgccattg gatgtgttga aacggcagtt ccagggaaat ggggctatcg ttgcacaggt
    70561 atgagttata tgaacttccc taaggttcta cttatcacga tgaatgatgg aattgatccg
    70621 gcttcgggta aacggtttgc accaagcttt ggtcatttta aggatatgaa gaacttttct
    70681 gaattagaaa atgcttggga taaaacacta agatatttga cacgaatgag tgttattgtt
    70741 gaaaattcta ttgatttatc attggaacga gaagttcctg atattctatg ttcagcattg
    70801 actgatgatt gtattggtcg tggaaaacac cttaaagaag gtggagcagt atatgattat
    70861 atatcaggat tgcaagttgg aattgcaaat ttgtcggatt cgttagctgc aattaaaaaa
    70921 ttggtgtttg aggaagaacg tataagccca agtcagcttt ggcatgcact ggaaacagat
    70981 tatgccggag aagaaggtaa ggtcattcaa gaaatgttga ttcatgatgc acctaagtat
    71041 ggtaatgatg atgattatgc tgacaaattg gttactgctg cttatgacat ttatgttgat
    71101 gaaattgcta aatatcctaa tacacgttat ggaagagggc ctattggagg aattcgttat
    71161 tcaggaacat cttctatctc agccaacgta gggcagggac gtggaacatt agcaactcca
    71221 gatggacgca acgcgggtac accgttagca gagggttgtt caccatcaca taatatggat
    71281 caacacggcc ctacatctgt tttaaaatct gtttcaaaat taccaacaga tgaaatcgta
    71341 ggtggggttc tcttaaatca gaaagtaaat cctcaaacgt tagccaaaga agaagataaa
    71401 ttaaaactaa ttgctttgtt acgaacattc tttaatcgtt tacatgggta ccatattcaa
    71461 tacaatgttg tttccagaga gacgttgatt gacgctcaga aacatcctga aaaacacaga
    71521 gacttaattg ttcgtgttgc aggatactct gcattcttca atgttctttc taaggcaacc
    71581 caagatgaca ttataggacg tactgagcat acattgtaaa ataaagaggt tctttttatg
    71641 gaatttatgc ttgacacatt aaatttagat gagattaaaa agtggtctga aattttgccg
    71701 ctagctgggg taacttcaaa tcccactatt gcaaaaagag agggttctat taattttttt
    71761 gaacgaatca aagatgtaag agaattgatt ggctctacac cctctattca tgttcaggtg
    71821 atttctcaag attttgaagg catcttaaag gatgctcatg aaattcgaag acaagcagga
    71881 gatgatatat ttatcaaagt acctgttact ccggctggat tacgtgcaat aaaggtgcta
    71941 aaaaaagagg gctaccatat cactgcaaca gctatttata cagttattca gggattatta
    72001 gctatcgaag caggagcgga ttacctagct ccatattata atagaatgga aaatctgaac
    72061 attgattcaa attctgtcat tcgtcaatta gctcttgcta ttgatagaca gaactctcct
    72121 agtaagattt tagctgcatc ctttaaaaat gtagcacaag taaataatgc tttagctgca
    72181 ggtgcgcatg ctgttacagc aggagcagat gtttttgaat cagctttcgc catgccatct
    72241 atccaaaagg cggttgatga tttttctgac gattggtttg ttattcaaaa tagtcgttcc
    72301 atttagatag agaggaaata catatgagaa tttttgctag tccttctaga tatattcagg
    72361 gggaaaatgc cttgtttgaa aatgccaaat caattttgga tttgggaaat tacccgattc
    72421 tattatgcga tcagttggtt tatgatattg ttggaaaacg atttgaagat tacctacata
    72481 ggtatggttt ccatattgtt ctggcgctat ttaatggtga agcttctgac aatgaaatca
    72541 atcgagttgt tgccttggct gagaaagaaa attgtgatag tattatcggt cttggtgggg
    72601 gaaagacgat tgatagcgca aaagctattg cagatttgat tgaaaaacct gttattattg
    72661 ctccaacaat tgcatcgacc gatgcacctg tatctgcttt atctgttatt tatacagatg
    72721 aaggtgcatt tgatcattat ctattttatt ctaaaaatcc agatttagtt ttggttgata
    72781 caaaagttat ttcacaagcc cctaagcgtt tattagcgtc tggtattgca gatggtttag
    72841 caacttgggt tgaggcgcgt gcggttatgc aggcaaatgg aaaaactatg ttgggacaac
    72901 agcaaacatt ggctggagtt gcaattgcga agaaatgtga agaaacgctg tttgcagatg
    72961 gtttacaggc tatggcagct tgtgaagcta aagtggtgac accagcatta gaaaacattg
    73021 ttgaagctaa tactttattg agtggtttag gttttgaaag tggaggatta gctgcggcgc
    73081 atgcaattca taatggtttt actgcattga caggtgacat tcatcattta acacatggtg
    73141 aaaaagtagc ttatggaact ttagtacaac tattattgga aaatagacct aaagaagaac
    73201 ttgataagta tattgagttt tacaaaaaaa ttggtatgcc aacaactcta aaagaaatgc
    73261 atttggatca agttggatat gatgatttaa taaaagttgg taaacaagca actatggagg
    73321 gtgagacaat tcatcagatg ccgtttaaga tttcgccttc agatgttgct caagctatta
    73381 tcgctgtaga tgcctatgta aattcaaaat aaacaataag gactactgtt ttccaaatgg
    73441 tagt
//
LOCUS       DAVLGK010000004        70493 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLGK010000004 DAVLGK010000000
VERSION     DAVLGK010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70493
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.004"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(269..406)
                     /locus_tag="VXE01_000301"
     CDS             complement(269..406)
                     /locus_tag="VXE01_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV0749290.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            complement(608..1195)
                     /locus_tag="VXE01_000302"
     CDS             complement(608..1195)
                     /locus_tag="VXE01_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0749291.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            complement(1288..1431)
                     /locus_tag="VXE01_000303"
     CDS             complement(1288..1431)
                     /locus_tag="VXE01_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749292.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            complement(1444..1824)
                     /locus_tag="VXE01_000304"
     CDS             complement(1444..1824)
                     /locus_tag="VXE01_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0749293.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(1817..2164)
                     /locus_tag="VXE01_000305"
                     /pseudo
     CDS             complement(1817..2164)
                     /locus_tag="VXE01_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2151..2402)
                     /locus_tag="VXE01_000306"
                     /pseudo
     CDS             complement(2151..2402)
                     /locus_tag="VXE01_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(2402..2572)
                     /locus_tag="VXE01_000307"
     CDS             complement(2402..2572)
                     /locus_tag="VXE01_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749294.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            complement(2759..3127)
                     /gene="rplL"
                     /locus_tag="VXE01_000308"
     CDS             complement(2759..3127)
                     /gene="rplL"
                     /locus_tag="VXE01_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV0749295.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(3203..3703)
                     /locus_tag="VXE01_000309"
     CDS             complement(3203..3703)
                     /locus_tag="VXE01_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV0749296.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(3742..3877)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3953..5212)
                     /locus_tag="VXE01_000310"
     CDS             complement(3953..5212)
                     /locus_tag="VXE01_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV0749297.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     KAVKEALTEMLQSGTTTFNDMYNPIGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(5514..7262)
                     /locus_tag="VXE01_000311"
     CDS             complement(5514..7262)
                     /locus_tag="VXE01_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749298.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLIRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(7264..8988)
                     /locus_tag="VXE01_000312"
     CDS             complement(7264..8988)
                     /locus_tag="VXE01_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749299.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVKLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQKLWQALEIAQAK
                     DFVSEKEGLLDVLVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(9046..9984)
                     /gene="msrB"
                     /locus_tag="VXE01_000313"
     CDS             complement(9046..9984)
                     /gene="msrB"
                     /locus_tag="VXE01_000313"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0749300.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(10132..10203)
                     /locus_tag="VXE01_000314"
                     /pseudo
     CDS             complement(10132..10203)
                     /locus_tag="VXE01_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10279..11148)
                     /locus_tag="VXE01_000315"
     CDS             complement(10279..11148)
                     /locus_tag="VXE01_000315"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV0749301.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(11150..12436)
                     /locus_tag="VXE01_000316"
     CDS             complement(11150..12436)
                     /locus_tag="VXE01_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV0749302.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(12587..13324)
                     /gene="mecA"
                     /locus_tag="VXE01_000317"
     CDS             complement(12587..13324)
                     /gene="mecA"
                     /locus_tag="VXE01_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV0749303.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(13525..14559)
                     /locus_tag="VXE01_000318"
     CDS             complement(13525..14559)
                     /locus_tag="VXE01_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0749304.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYFFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(14587..16020)
                     /locus_tag="VXE01_000319"
     CDS             complement(14587..16020)
                     /locus_tag="VXE01_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV0749305.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLVHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(16036..17022)
                     /locus_tag="VXE01_000320"
     CDS             complement(16036..17022)
                     /locus_tag="VXE01_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0749306.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(17024..18127)
                     /locus_tag="VXE01_000321"
     CDS             complement(17024..18127)
                     /locus_tag="VXE01_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0749307.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSTSNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(18117..18962)
                     /locus_tag="VXE01_000322"
     CDS             complement(18117..18962)
                     /locus_tag="VXE01_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0749308.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(19241..20515)
                     /gene="psr"
                     /locus_tag="VXE01_000323"
     CDS             complement(19241..20515)
                     /gene="psr"
                     /locus_tag="VXE01_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV0749309.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(20512..21360)
                     /gene="pheA"
                     /locus_tag="VXE01_000324"
     CDS             complement(20512..21360)
                     /gene="pheA"
                     /locus_tag="VXE01_000324"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0749310.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAENPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(21357..21833)
                     /locus_tag="VXE01_000325"
     CDS             complement(21357..21833)
                     /locus_tag="VXE01_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV0749311.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(21826..23109)
                     /gene="aroA"
                     /locus_tag="VXE01_000326"
     CDS             complement(21826..23109)
                     /gene="aroA"
                     /locus_tag="VXE01_000326"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV0749312.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDSKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(23201..23539)
                     /locus_tag="VXE01_000327"
     CDS             complement(23201..23539)
                     /locus_tag="VXE01_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV0749313.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(23550..24653)
                     /locus_tag="VXE01_000328"
     CDS             complement(23550..24653)
                     /locus_tag="VXE01_000328"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV0749314.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(24663..25829)
                     /gene="aroC"
                     /locus_tag="VXE01_000329"
     CDS             complement(24663..25829)
                     /gene="aroC"
                     /locus_tag="VXE01_000329"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV0749315.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(25839..26906)
                     /locus_tag="VXE01_000330"
     CDS             complement(25839..26906)
                     /locus_tag="VXE01_000330"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0749316.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPASITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(26925..27779)
                     /locus_tag="VXE01_000331"
     CDS             complement(26925..27779)
                     /locus_tag="VXE01_000331"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV0749317.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(27769..28446)
                     /locus_tag="VXE01_000332"
     CDS             complement(27769..28446)
                     /locus_tag="VXE01_000332"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV0749318.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(28443..29606)
                     /locus_tag="VXE01_000333"
     CDS             complement(28443..29606)
                     /locus_tag="VXE01_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV0749319.1"
                     /translation="MDRIRVSKRVEKKLAKGLVLLESSDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(30290..31714)
                     /locus_tag="VXE01_000334"
     CDS             complement(30290..31714)
                     /locus_tag="VXE01_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749320.1"
                     /translation="MPVYFSFVVAILLVIAFSTSLTAFYNVFYESKDLASYRPYAFKE
                     SEIIIAKGLSVLFPALTGIVPILAYFLALYISLAPSLWLGLPLMLLSLTLLFVSVALV
                     MVVAVHFLAQTTAFRKYQSIFSNVMIGIGVLIPLIFVFFLQSTFGSIVDKVRDIPFLL
                     YPLHIFYKIAVEPFSIEAILGLLAWIALTVFLLYLTKKKVLPRFYDVILLNSEEKVKK
                     ERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYLMMISLISKIRDS
                     QIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERKNVDFLKSLPFDFARYVK
                     VKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIFSCHHYFKDVKNL
                     STNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSPILAINLGVGALI
                     VLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(31905..32654)
                     /locus_tag="VXE01_000335"
     CDS             complement(31905..32654)
                     /locus_tag="VXE01_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749321.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQDLSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSSSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            32833..34287
                     /locus_tag="VXE01_000336"
     CDS             32833..34287
                     /locus_tag="VXE01_000336"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV0749322.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(34377..36995)
                     /gene="alaS"
                     /locus_tag="VXE01_000337"
     CDS             complement(34377..36995)
                     /gene="alaS"
                     /locus_tag="VXE01_000337"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV0749323.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNHNASQLSSKLVAIVADNAEVEAVSEGTTSLIFAETPFYAEMGGQVA
                     DHGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(37017..37502)
                     /locus_tag="VXE01_000338"
     CDS             complement(37017..37502)
                     /locus_tag="VXE01_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV0749324.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(37777..38016)
                     /locus_tag="VXE01_000339"
     CDS             complement(37777..38016)
                     /locus_tag="VXE01_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749325.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(38269..39339)
                     /locus_tag="VXE01_000340"
     CDS             complement(38269..39339)
                     /locus_tag="VXE01_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0749326.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(39336..40109)
                     /locus_tag="VXE01_000341"
     CDS             complement(39336..40109)
                     /locus_tag="VXE01_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0749327.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(40106..40912)
                     /locus_tag="VXE01_000342"
     CDS             complement(40106..40912)
                     /locus_tag="VXE01_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0749328.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(40893..42050)
                     /locus_tag="VXE01_000343"
     CDS             complement(40893..42050)
                     /locus_tag="VXE01_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749329.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(42211..43116)
                     /gene="murB"
                     /locus_tag="VXE01_000344"
     CDS             complement(42211..43116)
                     /gene="murB"
                     /locus_tag="VXE01_000344"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV0749330.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(43228..43980)
                     /locus_tag="VXE01_000345"
     CDS             complement(43228..43980)
                     /locus_tag="VXE01_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV0749331.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSTVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLSQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(43990..44721)
                     /gene="budA"
                     /locus_tag="VXE01_000346"
     CDS             complement(43990..44721)
                     /gene="budA"
                     /locus_tag="VXE01_000346"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV0749332.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGTGEQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELEERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     VGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            44863..46134
                     /locus_tag="VXE01_000347"
     CDS             44863..46134
                     /locus_tag="VXE01_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV0749333.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(46154..46969)
                     /locus_tag="VXE01_000348"
     CDS             complement(46154..46969)
                     /locus_tag="VXE01_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0749334.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(47126..47779)
                     /gene="phoU"
                     /locus_tag="VXE01_000349"
     CDS             complement(47126..47779)
                     /gene="phoU"
                     /locus_tag="VXE01_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0749335.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(47791..48549)
                     /gene="pstB"
                     /locus_tag="VXE01_000350"
     CDS             complement(47791..48549)
                     /gene="pstB"
                     /locus_tag="VXE01_000350"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0749336.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(48562..49365)
                     /gene="pstB"
                     /locus_tag="VXE01_000351"
     CDS             complement(48562..49365)
                     /gene="pstB"
                     /locus_tag="VXE01_000351"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0749337.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(49376..50260)
                     /gene="pstA"
                     /locus_tag="VXE01_000352"
     CDS             complement(49376..50260)
                     /gene="pstA"
                     /locus_tag="VXE01_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0749338.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(50250..51167)
                     /gene="pstC"
                     /locus_tag="VXE01_000353"
     CDS             complement(50250..51167)
                     /gene="pstC"
                     /locus_tag="VXE01_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0749339.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(51167..52045)
                     /gene="pstS"
                     /locus_tag="VXE01_000354"
     CDS             complement(51167..52045)
                     /gene="pstS"
                     /locus_tag="VXE01_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV0749340.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(52619..53923)
                     /locus_tag="VXE01_000355"
     CDS             complement(52619..53923)
                     /locus_tag="VXE01_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV0749341.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGHLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(53924..54697)
                     /locus_tag="VXE01_000356"
     CDS             complement(53924..54697)
                     /locus_tag="VXE01_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV0749342.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRSLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(54687..54965)
                     /locus_tag="VXE01_000357"
     CDS             complement(54687..54965)
                     /locus_tag="VXE01_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV0749343.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(54965..55366)
                     /locus_tag="VXE01_000358"
     CDS             complement(54965..55366)
                     /locus_tag="VXE01_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV0749344.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(55578..56195)
                     /locus_tag="VXE01_000359"
     CDS             complement(55578..56195)
                     /locus_tag="VXE01_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV0749345.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLCLKSRRK"
     gene            complement(56185..56958)
                     /locus_tag="VXE01_000360"
     CDS             complement(56185..56958)
                     /locus_tag="VXE01_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV0749346.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(56969..57706)
                     /locus_tag="VXE01_000361"
     CDS             complement(56969..57706)
                     /locus_tag="VXE01_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV0749347.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVFRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(57711..58841)
                     /locus_tag="VXE01_000362"
     CDS             complement(57711..58841)
                     /locus_tag="VXE01_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV0749348.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(58925..59314)
                     /locus_tag="VXE01_000363"
     CDS             complement(58925..59314)
                     /locus_tag="VXE01_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV0749349.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(59330..59713)
                     /locus_tag="VXE01_000364"
     CDS             complement(59330..59713)
                     /locus_tag="VXE01_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV0749350.1"
                     /translation="MLEVAYILVALAVIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(59714..60502)
                     /locus_tag="VXE01_000365"
     CDS             complement(59714..60502)
                     /locus_tag="VXE01_000365"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV0749351.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYHQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(60495..61430)
                     /locus_tag="VXE01_000366"
     CDS             complement(60495..61430)
                     /locus_tag="VXE01_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV0749352.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(61560..61736)
                     /locus_tag="VXE01_000367"
     CDS             complement(61560..61736)
                     /locus_tag="VXE01_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV0749353.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(61876..62583)
                     /locus_tag="VXE01_000368"
     CDS             complement(61876..62583)
                     /locus_tag="VXE01_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV0749354.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            62734..63762
                     /gene="queA"
                     /locus_tag="VXE01_000369"
     CDS             62734..63762
                     /gene="queA"
                     /locus_tag="VXE01_000369"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV0749355.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(64423..65550)
                     /locus_tag="VXE01_000370"
     CDS             complement(64423..65550)
                     /locus_tag="VXE01_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0749356.1"
                     /translation="MNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRFEKDETKYRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEKVTVD
                     RKEATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVIVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(66265..66816)
                     /locus_tag="VXE01_000371"
     CDS             complement(66265..66816)
                     /locus_tag="VXE01_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0749357.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(67166..67990)
                     /gene="nadE"
                     /locus_tag="VXE01_000372"
     CDS             complement(67166..67990)
                     /gene="nadE"
                     /locus_tag="VXE01_000372"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV0749358.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAIEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(67987..69447)
                     /locus_tag="VXE01_000373"
     CDS             complement(67987..69447)
                     /locus_tag="VXE01_000373"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV0749359.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(69563..70051)
                     /locus_tag="VXE01_000374"
     CDS             complement(69563..70051)
                     /locus_tag="VXE01_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749360.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(70041..70250)
                     /locus_tag="VXE01_000375"
     CDS             complement(70041..70250)
                     /locus_tag="VXE01_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0749361.1"
                     /translation="MAKNLKLKLARVELDLTQGQLADAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
BASE COUNT        20919 a        15960 c        13096 g        20518 t
ORIGIN      
        1 ttctgtctaa ctattggggt gcagttcaat aaatcttgac ccgttaaatt tgtactgaat
       61 aaactaaatg aaacttttat cccactcact aatactatta tatcaaccca ctacagttga
      121 caaagagaca aaccagccta atggctaact tgtcttcaat caagagagga ttctgttccc
      181 cccatataag cactaacatt ccaacgtgca catattggaa cgacatccat aacttcagag
      241 aatccctaaa gtttacaatt taaatgaatt aacaattttc ccaactaaaa gcactccagt
      301 taccgcaacg gtttgtactg aatgtactaa atcgcattcc atcaacttca tctgtttcgt
      361 caacttgaac agatactaat tgaagattta atacttcttc tgccatagct aactcctcct
      421 atttaaattt ttgggattaa gtgctttatc caccttcatt atactctctc cagcagtaaa
      481 atgcaagcaa tgatacaatg ttgtcacgta gaaaataatg tttccgtaac ttttcaaagt
      541 aacttccatc tctctcccaa aactggaagt tagttttaga agttacctaa aaatcaggtt
      601 acctatttta aaaaagcagc aaactataaa ctagtaggct ccacaccaaa tgtagcccca
      661 tactgcccca taagtccaat ttgtagcgta caagccctaa aaacatcccc agcgatacat
      721 acaaacacca agctataatg gttcctggat gatgtgctaa ggcaaataaa acacttgtca
      781 aagcaactct gatatctaat tttctgacca aattccataa aatttctcga tacagaaatt
      841 cttcaaccat actcgcattg attaagaaca ataaaaatga aaaccaagga atttgatgtt
      901 gaaggccaat taagtttgct tgattcgtgc ttccttgagc atgaatcaga ctaaaacata
      961 gacttataat cagtaggcta acaaattcaa caccaagcca tttcatccta gatttcatat
     1021 tgaccttatg cgcttgtttg cgttggccat acatccataa aaaagaaatg agtgacgaac
     1081 catagagaat ctgtagtata gttaactcac cgatacaaag aaatttcaat aagtatagag
     1141 ataccaatag gacatttact tgttggaata tataaactgg aattattctt ttcatagtta
     1201 cctccgaaat aaatcttcat aatctaaatc taatacctgc acaatccttt ctacccatgg
     1261 actttgaggc attcattgtt ccatcttcta gtggcgaatc ttttgataca aacgattcaa
     1321 ttcacttgga tagtgaaact ctcccgcaaa catttttctg gttaactcaa tccagctgat
     1381 atttctttca gccaaaataa tggacaagtt ctcccaaaat cgttcagcca tattgcttct
     1441 cctttagtta gataaataat gtgtttgcgc catgtaaatc aattgtttcg tatctcttgg
     1501 caatagagct ctagcctctt ccaaattcag acttggataa actcgcttat ttgaaaccgc
     1561 aagaggaagt ctgatggtta gttcaggatt ttttaaaatt atctcaacga aatccgttaa
     1621 tcttagattg tcacggttct taaatcgtaa taaattggga gataaaaact caaaacaatc
     1681 tgaagaatag ctcatcatct caattaattt gtcctttgtc atttcagaaa ctgaatgaca
     1741 agatacctct atgccatagt tttggaagaa atctaaaaga agttgatttc tttgtctatt
     1801 tttacttaga tagagatcaa tcatgggaga cctcccaaag attcggttcc atttgatatt
     1861 ctgagacgat taaggaatct aataaatttg cgaagttaat cggtttcttg tcttcatcat
     1921 aagcttttac agttacttgg gttgtaagta ttccctcttt tccctcggct cgatagcctt
     1981 gtccatataa aacaaaaacg agattttgat gatcatctac aaaggcatca accccattct
     2041 ttatgtcttg actttcaagg aattccataa cgttttgaag ataggactcg taaaatagtg
     2101 ggtagttgtg ttttttatgg taatcatcta aaaatgttac ttcaaactca catggagagt
     2161 aattttgact ttgaacagcc taaaagtgcc atcaaatttg aattggaata aatcaaataa
     2221 atagccccat cctcatcaat ccaacctttg ctcaaagaca actccaaccg atcttttaaa
     2281 actgagtaaa ccaccttaac ctccagtttc atattcttat accgttcact ctcaaataaa
     2341 agtttgggga gcttataata acgctctgat gtctgatatt gattagcggt aatacgcttc
     2401 attattgtcc ctccaagact aaaattccaa catttccaaa ttcatcaaat cggattaaac
     2461 ctacttgttc catttcatca actaactgag ttgcttttac aatatcaact cccatgatag
     2521 tcatgagatg actcttcacg aattgacgtg atgactgtcc ttccttttgc ataattacct
     2581 ccgaaacaca aaaaaagggg tagacaatct agtgtctacc cccgaaagtt tattaaaaca
     2641 aaaatcctgc caaagaattt ttggcaggaa accaaatcaa tttatcagtt tctatcaatc
     2701 gcttatcgct ctcaaagact ggtaaatagg gattccgcaa tcaaattgcg atactctatt
     2761 atttaagagt aactgaagct ccagcttctt ccaatttagc tttgatttct tcagcttctg
     2821 cagttgcaac gccttcttta acaagtgctg gtgcaccgtc aacaagttct ttagcttctt
     2881 taagaccaag accagtgatt tcacgtacaa ctttgataac gccaactttt ttgtcgcctg
     2941 cagatgtcaa ttcaacgtcg aatgaatctt tagcagcacc agcatcagct gcatcagctg
     3001 cagcaacagc tacaggagca gctgcagtta caccaaattc ttcttcgata gcttttacaa
     3061 ggtcgttcaa ttcaaggatt gaagcttctt taatttcagc aataatgttt tcaatgttca
     3121 atgccattgt tatttcctcc aaataagttt taaattttat aatagttttt ttcgtagcta
     3181 ggctacgctg tgtagcttaa gattaagccg cgtcttcttt gctttctgca accgctttga
     3241 ctgcaagagc aacgttgcgc actggcgctt gaagtacaga aaggagcata gaaagaagtc
     3301 cttcgcggtt tggaagagtt gcaagtgcaa gaatctcttc tttagatgcg acagcgcctt
     3361 cgattgcacc acctttaatt tcaagtgctt cagcgttttt agaaaagtcg ttcaagattt
     3421 tcgctggtgc gataacatct tcattagaaa atgctactgc agatggtcca acaaatacag
     3481 atgcaagatc ttcaagacca gctttttcag ctgcacgacg caagattgag tttttaataa
     3541 ctttatactc aacttcgctt ccacgaagct cacgacgaag aactgtatct tgctcaactg
     3601 tcaaaccacg agcgtctaca acgacgatag atgcagcagc tttcattttt tcagctacta
     3661 cgtcaactag ttccgctttt ttagcaataa ttgcttcact cattagtgtg ttcacctccg
     3721 taattatttt gcttggggaa tttttcaaaa agaaaaacgc gcccaaacct agacacgaaa
     3781 gtacaatacg cttcttttta catgatacgt cttgtcctcg gtaggatatt tatgagtcga
     3841 gctcccctac tgtcttaggc agttttttta aaccgtatat aagtatagca tagtcaaaaa
     3901 aagaatgcaa gatttttgca aacttttttt aaaatttttc gtaatttttc ttttaaagtt
     3961 ctactgtcag gacttgacct tgcttaacaa cttgttctcc ggcgatataa acatcatcta
     4021 catcactaga tttaactgca taaaccaggt gagacagcat attttcctga ggttggagat
     4081 gaattttccc ttgtggttga atgaccagaa aatctgcttg cttgccgact tccagacttc
     4141 ctatctgatt ttccattcca aggaccttag ccccttcgat tgtcagtacc ttgagagctg
     4201 tttcgattgg aaactggctg gcatccccac ttttcatctt ctgaagaaga gctgcagtcc
     4261 ttccttcctc aaacatatct agattgttat tggaagcaac cgagtcagtc gcaattccga
     4321 ctgctactcc cgctttttgg agctggataa ttggagcaat tcctgatgcc agtttgaggt
     4381 tactgatagg attgtgggcg atagccactt gagaagatgc caagcgttca atttctctct
     4441 cgtttaattc gaccccgtga gcaaatacgg acggatgatc taaataaccc agttcttcaa
     4501 gaaaagcaag ggggcgtttg ccgtatcgtt tgaggataat tcctgactcc tccttggtct
     4561 ccgccacatg gacatggagc ggaatattta gctcttttgc catttccaaa ctcgcttcca
     4621 gcaagtctct actgcagcta tacggagaat gaggtgctac cataaccttg aaatttggat
     4681 ttttatattt taagatttca tctatgatgg atcgagttct gcttatagtc tcagcagttg
     4741 tttctgtctc tgaagaaaag agagtcggag aaaaataaca acgcatcttg gaagttttca
     4801 ccacctgata aatttgctgg atatccacac caatgggatt atacatatcg ttaaaggttg
     4861 ttgttcctga ctggagcatc tctgtcaagg cttctttgac cgccttggta gtcatgtcgg
     4921 gagtaaactc agattctgct ggccagatat agtcattgag ccattcatgg agattgctgt
     4981 catctcggat ccctctcaga cctgtcattg cagaatgggt gtgacaattg accaaaccag
     5041 gcataatcca agctccctga tagtctataa tctgctcagc ttgttctaaa aacgctggct
     5101 tatcttgacc gacatagacg atttgagaat ccttgactgc taagattcca tcaagataaa
     5161 catggaaatt ttgatcacaa gtcacgatat ttacatgctg aaagactttc attatagact
     5221 ccttttttaa aagacaagtt gtactctctt caaaccactt cagattcact ttgccgtagg
     5281 tgtggttact gacttcgtca gttctatctg caacctcaaa gcagtgtttt gagctgactt
     5341 cgtcagtctt atctacaacc tcaaagctgt gctttgagca acctacggct agcttcctag
     5401 tttgctcttt gattttcatt gagtattaca gtaaacaatt tttctagcta ttgtaacaaa
     5461 aaagtcactc gaaggcaact tttttcgtcc ataaactttc aaaagagaat ggcttattca
     5521 gaactaaaag ccgcagcttt ttgcatttgg taatacttac cctttctatc catgagttct
     5581 tgatggttac catattcaac aatatcacca tctactaaga caagaattaa atccgcatcc
     5641 tgaatggttg acaaacggtg agcaatgatg aagcttgtgc ggcccttcat gagttttgca
     5701 aaggcatcct gtaccagcac ttctgtccgt gtatcaatgg aagaagttgc ctcgtctaag
     5761 ataagaatct ttggaatagc cagaaagact cgggctatgg tcaagagctg agcttggccg
     5821 acagagagag attctccagc attttccaac ttggtatcgt atccctgtgg caactgttgg
     5881 atgaaaaagt ctgcattagc tgctttggca gcagcaatta cttgctctcg actggcttca
     5941 ggattgccaa aggcaatatt atcatgaatg gtcccttgtg tgagccaggt ttcttgaagc
     6001 accatgccaa actgctgtct caatgatgct cgtgtataat cataaatgga ttgcccatcc
     6061 agcaagatat ctcccgagct aatgggataa aaacgtataa ggagattgat aagagttgat
     6121 tttccagcac ctgtcggacc aacgatggct accttactac cagctggaat atcgatagac
     6181 aagtccttaa tcaaaatttt ttcaggatgg tagccaaaag agacatgttt aaaggaaata
     6241 gctcccttaa cttggtcact ggtcaagact tccttacctg tttcagccac ttcagggcta
     6301 tctaagactc catagatacg ctctacgcaa gccagagcac tttgcaactc agctagcact
     6361 gaagaaatat cgttaaaggg cttggtgtat tgctgaacat agttcaaaaa agtcactaaa
     6421 cgaccgacgg tcaaggttga acccatcatg atacgataag ctcctactcc agctaaaagg
     6481 gcataaatga gtgcatttac aaagcgagtc gaaggattga ccgttgaaga ataaaagatg
     6541 gctgactgag aatagcctga gtagttgtca tgagcctcac gcaatctttg gataaactct
     6601 gtttgagcat tgaaggactg gattatagtc tgctggctaa gcgattcttc aatcaactgg
     6661 gtctgaatcc ccctcgtctc tgtttgcttc tggaagagat gataggatct cttggcaata
     6721 aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga ctaagagagt catgaggaga
     6781 tgaatttgga gcatggctag aatactaacc aaaatcatca aaacaccaat gaaaaattgg
     6841 ttaaaaatca tagtcaagcc agctgccaac tgttcgatgt ccgtggttac acgactgacc
     6901 atctctccat tgccttgccg atccgcaaaa gcaatcggta accgatggag tttatggatg
     6961 attcgctctc gtaaatctct ggtataagag aagattagac gattatagag gagaggattg
     7021 gcccattgta ccagagtatt tcctattacc accaagagca tctgtagaaa aatctgccaa
     7081 aaaactggtg atgaaccagc cactaggact tggtcaatga cctgcccaat cagaataggt
     7141 aggtaaattg ataagccaac ttgggcaata gttcctagaa aggctaggaa aaggaggaag
     7201 ggatggtttg ctaaatctac ggctaaacgt ttgagcgtct ggtttacagt ttgtcgtttc
     7261 attctagtcc tcctttccat gttgggatgc attgatttca cgatagactt ggctggattt
     7321 catcaagtca tcgtgcttgc caacagctag caactcacct ttttccaaga ggagaatctg
     7381 gtccgccatc tgtaaagttg aggttcgttg agagatcaaa attaagctcg tgtttggaaa
     7441 attttctcta atagctttca agagcttgga ctctgtaatg gtatccagtg ccgaggttgc
     7501 atcatctagg atgagaaacg gagcttggcg caagactgct cgggcgatag acaacctttg
     7561 tttttgtcca cctgagaaat ttcgcccccc tgcctcaact aggacatcca agagtccttc
     7621 cttttcactg acaaaatcct tagcttgcgc aatctccaag gcctgccaga gtttctggtc
     7681 agatacttct tgattgaaac ctagagtcaa gttggaacga atagttccct taaagagttc
     7741 gaccttttga ggtacatagg caatccaaga ccgccactgc tccaaattaa gaggactacg
     7801 tccattttga taaaggtcaa tgttcccctt gtctactgga taaagtccaa gtaagagttt
     7861 caccaagctt gatttaccag aaccagttcc cccgatgata cctagaattt gtccttgagt
     7921 catatcaaag gaaatgtatc tcagagaagg ctgggccgca tcaggatagg taaaggtcaa
     7981 ttcttggact tgtaaaacct tatctctggt agcttgcttt tgttctaact ctgaatggat
     8041 atcctctgga gcctcaacaa agacttcctc gattcgcttg gctgagatat aggactggtt
     8101 gagggaattg atcaacatgg ctagcttgac caattccacc aaaatctgta agaggtaatt
     8161 gataagagca atgagagcac cttgactgag cactcctcct tgaattgaaa tatagccttg
     8221 ccagataata acgagaagag ttccattgac aatcagatag gtcagaggtg ttaataaact
     8281 agaccagaaa cctgtctttt cttgtaatct agcataaact tggttaaggg tttgaaaaat
     8341 ctgtaactct cgtttttctt gaccaaaagc acgaataacc cgcatccctt gcaattgctg
     8401 gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga ctactgtaga gaggattgac
     8461 caatcgagat aaccctacaa tgacaatggt caaaatggca accatgacta agaaccagaa
     8521 agtcaactca gctgagattc gataagccat aaaaatggca ccaaaaacga taatgggcgc
     8581 tcgcaaaaag agacgcagga attgattgat accagtctga atctggtagg tatccgaagt
     8641 caagcgagtg accaaactag aagttgtcag acggtctctg ctatccttgg gcaaggaaag
     8701 aatatgacga taaagatcgt ttgtcaattc cttagcaaag cctactgctg cctttgctga
     8761 gtaaaattga gctatcaagg ccactaaaac gccaattact gcaaagataa ggagcaggcc
     8821 aatctgcatc cagagatgac cttgatctcc ctgaggtaaa gattggtcaa caatcccagc
     8881 aatcaccatg ggaaccaaga gctcaaaaac agcttctaac agcttgaaca agggggctaa
     8941 aattgattcc ttgatgtagg gtttgaagta agataatagg tgtttcataa atcccttcta
     9001 ttcatattct agaaatgaag aaagtgggaa gccccactct ctgttttatt tgtttaagta
     9061 aggcaataga tagccatatc ctgctttttc catctcatcc ttggccacaa agcgtaaaga
     9121 agcagaattg atacagtaac ggaggccgcc taactcccgc ggtccatctg tgaaaacatg
     9181 acccaagtga gcactgcctg aacgagaacg aacttcaatt cgctccattc catggctcag
     9241 atccttgtaa taatgaatca actctttgga aatcggacgg ctaaaacttg gccaaccaca
     9301 acctgaagca aacttatcct tggcaaaaaa gagtggctca cctgtcgtaa tatctacata
     9361 aatcccctct tcaaaggttt ggtcataggc attggtaaac ggagcctctg tagcagcttc
     9421 ttgtgtgaca cgataagact cttcagatag actggccttc aacacctctt gactaggctt
     9481 ttcatagttt gctgcatcaa tcaatggctt atcagcatcg gtcacatcga tatgacagta
     9541 acctgaagga ttcttcctga gataatcttg gtggtagtct tcagccagaa tgtagtggcg
     9601 taattgctcc acttctactg caatctttcg acccagcatg cgttcctgct cctgtaccac
     9661 tgtgtagata gctggcaaat ctgcttcatc ctgataataa atcccagttc gatattggcg
     9721 accacggtca ttcccttgtt gattgataga tagaggatcg ataactcgga aataataaag
     9781 taaaatctct ctgagtgaca cttccttctc atcgtaaatc acttggaccg tttctgcatg
     9841 gtctgtttcc ttgatcaact ggtaattggt cgtttcgact tgaccattag cgtagccaac
     9901 actggtttct agcactccag aaatgcgtga aaaatattcc tctaggcccc aaaaacaacc
     9961 acctgctaga taaatttctg ccatctttat ttctccttta tcacgttttt aactaatact
    10021 cttcgaaaat ctcttcaaac cacgtcagcg tcaccttacc gtatatatgt tactgacttc
    10081 gtcagttcta tctgcaacct caaaacagtg tcttgagctg acttcttcag ttctatccac
    10141 aacctcaaaa cactgttttg agcagcctgc ggctagcttc ctagtttgct ctttgatttt
    10201 cattgagtat aaacttcttt tcacaaaaag gatatgaaac cctctggtca agagtttccc
    10261 catcctatct tctattcttt attttgcttc tacacggaca ccttgggtat caactctcaa
    10321 gtcatgcagt tttcctttga aaggttgctt ttccaattct gccttaattg ttggcatctt
    10381 gtcatgagaa gccagaacca taactgtcgg cccagcacca gaaaggtagg ttgcataggc
    10441 cccattttct ttggtcactt gcttaatcat cgcaaattct cttaccaagt cctgacgata
    10501 gcgctcatgg aagaggtctc cctcgattgc ttgcccagcg gtcaccatgt ctcctgccaa
    10561 caaggcagca accgctacat tggcgataga acttgcagca acagcttcct tataagacaa
    10621 ttttttaggc aagacactac ggctgtcgcg agtacgtaat tcatagtttg gaatgtaagc
    10681 tagaaaatca cactctggaa agtctgctac gatagcagag acttgccctt caacagaact
    10741 tgcaataacg agattaccat aaatggctgg agccacattg tcaggatgcc cttcaatctt
    10801 ggtcgctaac tgcaattttt catggtctga taagttgagt tgacccagtt ggttggctag
    10861 ttcaatccca gcaacgataa ccgagctgga agaacccaaa ccgcgcgcca aagggacatc
    10921 actggtcatt ttcaagcgtc ttggttgcaa gtctggtaca atttgcaaag cgattttgag
    10981 caagagatta cgctcatcat gtggaatcca tttgccaatc tggtgttcaa tcagccactc
    11041 atctcgttct tcgcagacct caatttgaag atacttggtt acagctacac cgaccgagtc
    11101 aaaacctggc ccgatattgg cactggttgc aggtacaata atcttcatct tattctccta
    11161 gcaccttgaa ggtattcaag aggtcgaatt ctgaaacctt cttcaattca gctgagacat
    11221 tttcaagctg ggctttatta atcttgtgtg tgatgataac gacacgcgcc ttgtcaccct
    11281 ctttgccatc ttgaaggatt tgcttaaagg aaatatcttg agcattgaag atttcagcca
    11341 acttcaagac ctgacctttt gagtctggag ccaagattga gaaatagtag tttgctttga
    11401 catcttcagg atttgccaag accaagtcac ggctatattc gttgaagtct ttgccaatgg
    11461 taccatcatt caaacgacga acgatacgga caatatcagc tacaacactt gttgcagttg
    11521 gtttttgacc cgcacctggt ccgtagtaca tagactcacc aataccgata gattctacaa
    11581 agacagcgtt cattacgcca ttcacactag caagtgggtg cgctttaggt aggaaggttg
    11641 gagtcacttc tgcagcaata cctgaagaag tttcctcaat agaaccaacc aatttcacta
    11701 cgtaaccaag ctcttgagct acagctacgt cttctggtgt gatattgcgg attcccttgt
    11761 gggctacatc atcaaaggca atcttcatgc caaaggcaaa ttggctcaaa ataaccatct
    11821 tgtaggctgc atcaatccca tctacgtcat tcgtcggatc gctttctgca aatcctagac
    11881 gttgtgcttc cgcaagagca tcatcgtaag accagccttc ttccaccatc ttggtcacca
    11941 tgaagttgga agttccgttg actactccaa gcacgcgcgt aattttatca gaagccaagg
    12001 aatttgctaa agtacgaaga attggaatcc caccagcaac tgctgcttcg tagtaaagtg
    12061 ctaccttgtt agcttgagcg atttctagca attctgcgcc atggacagct aaaaggtcct
    12121 tgttagcagt aacaacgtgt tttccagctt ccaaggcacg agtgataaag gttttagcag
    12181 gctcaatacg ccccatcaat tccactacga tagtaatatc ctggtctgat aaaatatcat
    12241 ccacattggt tacaaagtta aagtcattcc ctgctgcaag caagcgattt ttttcatctt
    12301 catccttgac caatacctta gcaactttga tatctgaatg tgctgattga ttgatttttc
    12361 ctccattttc ctttaggagg aaaggcacac cacttgcaac ggtaccaaat cctagtaaag
    12421 caattttaac tgtcatcttt atctcctcga aattttctaa tatagccatt ataacagaat
    12481 tttgtgaaaa ttcctattat agtaaatcac tatttcagta taaaaagaaa aaacgaatca
    12541 gacgattcgc tcttcttaaa atctgaaaat agctttccag aaaggattag ccgatttttt
    12601 gcagattgag cactgcatcg tgactcatca agacttgacc atactcttgt aagactgagc
    12661 gactaatatc actatcgtct gcaaactcgc gcatacgggc caacagccaa gctggatatg
    12721 ggcttggatg attttcaata tccactaaaa tggtcaaata atagcgctcg ttcattttgt
    12781 agagttcaga agtttccatt tcaaaagtca ctgtcttggc aaaagctacc aagtcagcca
    12841 acttagcaaa agaaaggatg tagtagatgt aaggttcttt cttactctca gcttcttgtt
    12901 cagcctgctc ttgctcttct tccttggctt caacttgctc aagagattga atggcttcga
    12961 tatcatcctt ggttttgtct gcgatgcttt tttccagggt tttgataaat tcatctggag
    13021 acatttgagc caattcttcc atatctggca aatccgataa gtcttcaaaa tctagatttt
    13081 ggtcaatctt tgacttggtc acaaagacat ctaccttatc aggttttgga gtcacacgga
    13141 agctcaacat gcctgtatcc agaaagctat caggcatctc tagctcatcc aagatagcat
    13201 aaaagaactc ttctgttttt tcttgaggaa cgagaaagtc agcaatctcc attccacgat
    13261 ccatcaaatc ctctaaagac atcgtgattt ttaaagttgt atcactaatt tgtttcattt
    13321 tcattgctag taacctcata ctttcagttc tatctattat actagatttt tacgatttta
    13381 tcaaaagaag gctcctctat acggatagat tttccctagg gtaacttctg taggagactc
    13441 caaaagaaaa tttctgcaga cagatagaaa aagccttcaa aatcagctct tagccgattt
    13501 tgaagacctc atacatcaga atacttataa tttaaaggtt gctacaccga ggatagaacg
    13561 atttaagttt ctgagaattt gaagactttg ctcaaatttc ttataacgag tcactccgta
    13621 ctcttcaaca agaaggactg tatctctttc caaaagagat gatacatcct gtaaatctac
    13681 aaaatgcatt ccttttaaag cttcttgact ctgtttcaat ttatctagga tagctttatt
    13741 tgagctaacg atggtcaatt cctgtccagt atttttgtat gacaaaacat ctgctaggtt
    13801 agcaattgtt gtaatctctg ttacaaaatc aatttgatac tgagaaaaat cacctactct
    13861 attgattgtt ggattaaaga aataaactaa cacatttccc atcacaacca aaatcacaca
    13921 aaccactcca ataacaacta aacgaagaat cagatttttc acatttaagc caagcgctgt
    13981 ttcaccattt gcgttcaatt ctttagagtt gatggtttcc agtttttcaa tttttacatt
    14041 tgcataggca tgtttaaatt tctcaatcaa cccatcaatt tttttctcta acaagtcatt
    14101 ggcatcttta cttgatgtca aaattttcac accaacccct gcatcgtcaa tcatatagta
    14161 gacggtcaat tttttccacc aatagtcatt cgttgaattt ttcaaggttg tttctgtcgt
    14221 gtctaattca ctggcaattt ttttcaactc actgggttct acatcattga aaagataagc
    14281 tccattcaaa ttaccatcaa tcaatttccc ataaaaatca ctataaccac caatttgatg
    14341 attcaaaatc gttttggccg actcttttgg aggagtgatt ttatagataa gataagttga
    14401 ataacttgtt gtatctttga cagtgttttt attcctaact gctttaattg taaatggtac
    14461 agcaatgaga gcaaataaag cgatgagagc taaaatattt gcttttcgct ttttataaag
    14521 atttgcaaac aaatcagcta ctgaataatg ttcaaacatg attttttctc ctttgtttag
    14581 tagatactag ttttcctttg taagcatttt tgctacaaat ataatcacaa gaacaattcc
    14641 ccagaattgc attgtaaata aattgaagaa actttctgaa aagctgcttc ttggcataaa
    14701 gaatagatta ttcaagatga gtagggataa agcaaatagg attgtccttg agcgataggc
    14761 tacttgcagc atggctataa ataatacgcc gagtaagaaa ctaagcagaa agactccaat
    14821 cataccatag tcggtataca actccatgat ataactactt ccgataccat gccctttcaa
    14881 gtattccttg ttcaagacaa gataggatag attgtgggca taactattac tatcaatagc
    14941 tagttccaca ctattggttg tatgttcaaa ggcttttcct ccgaaaatgg ctcccaaact
    15001 cccccttgca aaataatcaa gaacaggacc aaaagtaaaa ttacggaaat ctcggtaagg
    15061 gaggctactg ttaaatagaa aacctcgagc cagaacacca aaactagtcc cttgtttata
    15121 gataaagtca agtaagatat cccagaaacc tgtatgggaa acttggacat tatcccgtac
    15181 ataattgagt actcccatcg ctaacatgag aataggagaa cctacaaaaa tcgctaactt
    15241 ttctttaaac ccaatccatt ttcctttttc agtttgctcc cgcataaagt aataaacaaa
    15301 agcaaataaa atacttaaaa taaagggatt tcgtgtccca attgccaaat gaatagtatt
    15361 agctgcaata aaggagacaa gcactgctgt ggcctgcaat ttctttggct tggttgccag
    15421 atacatacac attgcataga ccgtaaaggt agacaaaatg taggtaaaat aaggcagttt
    15481 actttcaaaa tttgcatagt aggcatagta ggaagtctgc aaacgataca agagccgttc
    15541 aaataaccga atgaaataga aaggataagt tagaagaaaa actcctagtg atacaaagcg
    15601 taaccgcttg atataaacct cttttagaga atttcctata tttgctactt ttattttctt
    15661 cctagctatg aagtaacgag ccaggacgcc tcctgttgtc aagcccagaa tcgaaaccat
    15721 gacaactata aaggcaaaac gataggctat tggatgatag gtgtccaaag caccatccct
    15781 aaaataatca atggtcggtc ttgataccag aaatacaaaa atggttaaat agaaaataaa
    15841 atggactaag taatacttga tatcattcca acaagcaatt aagctactaa ccaacaagaa
    15901 caataaagta gaaagtaagc taacattatt attattaaac agatacacaa ttccacttac
    15961 tagcgtcaag gcataactga ctatggtcaa actaaataat aatcgtttcc catcaatcac
    16021 ttggtcaccc ccgttctaat gtaatttttt agatttttca atatttttca gtaataagaa
    16081 tcggtataag gaaatattta tgaatagggc caaagcacta attcttctcc ccttacggaa
    16141 aattggattc ctagaaatag caaaagcata gccttttaaa aaacgatgaa tctgagaata
    16201 ggcttcaaac tgtttatact gatcatctag caacatctta tccagaataa agaagtgagc
    16261 ataggccaat ctgaaaaaag cgacctcttt caagtcagga tagtttttca caacttcatt
    16321 ataaaacttt tggtagatat caatataggc taaatccttc tttgcatagg gtttggtcgt
    16381 aatactatcc cctctatgga aatagtaata atagggttta gtattaacca catacttctt
    16441 ggccaacttg attaaatcaa aatggtaata ggcatcttcg taaatcaacc ccttaggaaa
    16501 ggatagggca gttgcaattt gtctcttgat tagcttattg caaatcgtcc caggtatttt
    16561 ttcacctatg aggtattcct ttagaaatgt ttgagaatca cagacaaaat agtcatcctg
    16621 attggctgac tgtgggcttt catcattagc atagacattc atgacaccac agcttgaaac
    16681 atccgcatct tcttgaacta attgctcata taagctctga atcatttctg gatggatata
    16741 atcatctgag tcaataaaaa tcagataatc cccgtgagcc tgcttcatcc catcatttcg
    16801 tgcttgcgac aatccttcgt tctttttatg aagcactgac accctgtcat cttgttcagc
    16861 gattgaatca cacaagcgac cactttcatc tgttgcacca tcatcaacaa gaataatttc
    16921 cagattttga taggtctgct tctgaatgga agctatcgat ttttctaggt actgcgccac
    16981 attatagact ggcacaatca cactaattaa tgcagtttcc atgctactcc tctaatagtt
    17041 tttctacttg ttcgatttgt tttgtaattg taaattgttg aatgaattgg ctagcctcat
    17101 cgacatcaaa gtttgaggta gaagtcatgt aattagtaat cgcctgagct gcctcttgat
    17161 tgctctcaat gatttgtcca aatcgtcctt cttgggataa ttcctcagcc cctccaacgt
    17221 ccgtagagat aaaagggagt cccagactca aggcctccac atacactcca ggaaaacctt
    17281 cttgtttaga catagacaaa agaactttcg tctgagatag atactgataa ggattttttt
    17341 gataaccaag gaaatgtaca tagtcctcaa tcccatactc tttgactcgt tttttcagtt
    17401 cctcttccat atcaccagct ccgataaaat agagatgata gttttttccc tcttggtgta
    17461 ataatcgtat cacttccact acacggtcag aacccttatt ttcctcaatc cgtccgatag
    17521 tacagatact ttgaggagca atctcgatat cgatcttctc ttgagatttt tctagaatag
    17581 tctgaaaatc atatccattg tagattgtct gtaatttaga agcataatct ggataaactt
    17641 ccttgataga attgctggtc ttttttgaaa tccctacaat tgtattcgca gcatccaact
    17701 ggcttctatg tgattctctt ttagagctat ccttaagaag ttcttcaata cttccatgaa
    17761 tccaagatat cttcttgact tctcttcttt tagagaacaa cagtggtgga ttcataatgg
    17821 taaaagaaac ttcaacatca taatcatctt ttacaagcaa acgacgagcc agtcttggaa
    17881 aataaattct cattctccac aaaaaagctc gtaaccatct ggtttggcga taatcttgaa
    17941 gggattttaa aatgcgtaca tgctttggaa cagattcata tcccttgtca aagtgctcca
    18001 tttcaagaat atcaatatca tacttttctg gatccagatt tgaaacaatg gttgatagaa
    18061 tcttctctgc accacctcca agagaaaaag accacataaa aaataagatt tttttcttag
    18121 ccaccatatt ctcccttgta ttctgtataa gacttatcca tatcagcgat gacagcatca
    18181 tgatgcggta cctgcttgtc tgctggtgga ggcgtcatat aatccccaaa agcagttctg
    18241 agatagacat catagccgat tggaataggc atctctgttc cttcaaatgg caagaaaaga
    18301 ttgtcttcaa aagatgtgat tgggtacttg tttctcatgt agccaggacc tgagcataat
    18361 tctgtaatgc catcacaatc agccaaatca tacttagtca tttctttctc agcttttttc
    18421 cagatgcgat aacggagaga ttttggagtc aaacccagta aaatgcgact tccccatttc
    18481 atgagagcac catgcttttc tggaatagtt tgcgcacaaa agagtgaata aatcaaggcc
    18541 caacgaacct gttttttccg ctcagctgga tctttcggat aataatccaa aggcaaaaca
    18601 tccaaggcca gaccatgtgg caaatccaaa tcctgctgat aaggcttgat acaggtggtt
    18661 tccttgtcac gaatggtaat aaaaagatta cgatcaacaa aatccttgta actctttgac
    18721 aagaaataac gttcatctgc ataacgaggc cataattctg ctaatttctc ataatcttta
    18781 cgaggcataa aaaagtctag gtcgtcgtcc caaggaataa atcccttgtt tcgaagggta
    18841 ccaatagcgc ctccgccaca gagataacag agcaaatcat gttctttaca aaaggccaca
    18901 aaatattcag ccatctccag actacgagcc tgaattgctt ttaaatcagt catattgttc
    18961 attattcttt ctatcgtatc gtttcattat accacaaaca aggggtgaaa atctattgca
    19021 gactgtaaaa aatcaaagcc tgactgctat ccaaatagct atcaaacttt gatttttctg
    19081 tcttatactc ttcgaaaatc tcttcaaacc acgtcagctt caccttgccg taggtatagg
    19141 taactgactt cgtcagtctt atctacaacc tcaaaactgt gtttttagca gcctgcggct
    19201 agcttcctag tttgcacttt aattttcatt gagtattatc ttatctcaag cccatttgag
    19261 cgagcttggt ttgatatttg ttttgatcaa ccagcaagcc caagcctcca taaacatcat
    19321 aggcatctac ccagtcaccc agttctggaa tcgtcaattt ttcaatacca ttttttgctc
    19381 catccaaaac agataaaccg tttgttagga ggaaagtata gggtacgttg gttgaggtca
    19441 tagcaaaaac ctttccaaga gcttcagaac cagtgaaaag tttagtggga tctttaattt
    19501 gctctaaaat tgctgttaaa acttgttgct gtctttttgt acggccgtaa tccgcctcat
    19561 catcatcacg gaaacgagca taattgagca gggtcgagcc attcatctgc tgttttccga
    19621 ctttaatggt ttgggttgga gactcagtct cggtagcata taaatcatct ccgactgtag
    19681 cttctgttag gggacgccca ttcaatgttg aaaattgagc atcaatcgtc accccatcag
    19741 ggaaaagcgt gtcaatcgct gtggcaaagg cctggaaatc aaccaaggcg tagtacttaa
    19801 tgtccaagtc aaaattatct tttaagactt ggcgaaccat ttctgcccct ttttgcccct
    19861 cttgttctcc taactcgtag gctacgttta acttgttatc tgtctgtttt ctaccattaa
    19921 tcacttgact ataaccatct atatagacca aattatcacg cataaaactg actagcttca
    19981 ttttcttatc tgagcccccg acatttaata ccataataga gtcagttcgt gtctcaacac
    20041 tgttctggcc gattcgacca tcagtaccca tgattaaaat attaactcca tctctagtgt
    20101 cctgaccatt aaagacttct acttgagctg cccgggcatc agcagttttc tttgcgctag
    20161 catcttggta accacgcaaa aacatgaata ccatggccaa agccacacag accaaaagtg
    20221 aaaaaatcac cataaaaatt cgtttaagac ggagcttccg tcttttcttt tttggaggga
    20281 aagagagtgc ttgtgatttg gattgtgagc gactccggtt cgcatagctt ggtaagtcaa
    20341 cctgctcttc tctttcttgt tccaagctag agctactatt tcccctagca agagttagct
    20401 tttcttgcaa ataggcaaac tcattttttt ctctctcatt gagatagtga atatttttta
    20461 gcaaataatc ataacgcaac tgctcatgat gacttaaggg attttcttta ctcatcttct
    20521 ctcctttcca tggtctgata ttggataaat aggataggca cccagaattt tatactggat
    20581 tccaatcgct tctaattctt tttgggcaaa gtggaccaag tccttatcgg tataatccac
    20641 atcgataatg aaaaagtatt cacccagtgc tgtcttgagt ggacgacttt caatttttgt
    20701 caagtcaatt cctcgccaag caaaggtcga cagggcctta taaagtgcac ctggaaggtt
    20761 gtcaggtaat gtcaaggcca aactcatctt ttcagtttgt gcttgcaagg gaatactagg
    20821 attttcagct cctagaaccc agaaacgtgt gaaattggct tccatttcct gaatatcctc
    20881 ggcaatcagt tccaatccat attcttcagc agaacttcta ggtgcaactg ctgcaaaggg
    20941 ctggtctgga tgttcggaaa taaaacgggc cgcataagct gtactagctg ttacctcgat
    21001 ttgagcctct ggatattgtt catcgatgaa tttctttcct tgagccaagg cctgtggatg
    21061 tgaaaaaatc ttttcaatct tagtatggcc tggaaccacc atcaactgct gatgaatagg
    21121 ctgaacgatt tctgctactg cttggatgtg agcctgatga aaaagatagt ccaaggtttc
    21181 atgaacacta ccctcaatag aattttcaac tggcaccaca gaatagttca ctaatccttg
    21241 ctcataagcc ttgatgacat ctgtaatgtt ggcaaaagcc tgcaattcct catgaggaaa
    21301 agctgtctgc acaacgtggt gtgaaaatga tcccttggga cctagataag caattttcat
    21361 cttagttcct ctataatttc ctctgggctt agcttggtca catccaaaac ccgactagcc
    21421 acttcctcat accaagcctg tctttcttga aaaatagcta ctagttcttc cttgctatta
    21481 tttagaaaaa gcggtcgctg attgtcctta tcagctacga tacgtaggta gagggtttca
    21541 aaatctgctt tcaggtagat gttatctgta ttagtcttga gtaagtcacg atttctctga
    21601 gaaataacca ctcctcctcc agttgacacg acttggtctg tttgtagtaa atcagctagg
    21661 acttctgatt ctacctgacg aaaggctgct tctccctttt cagcgaaaaa attcgcaatg
    21721 gacataccta ggcgcttctc aatcagagca tccatatcaa ggtaattagg gtccaagcct
    21781 cttgcaatag tcgattttcc agcccccata aaccctaata acaccttagc catgaatcaa
    21841 gctctccaaa tcatcaaaga aactaggata gctggtattg atggcttctg cacggtcaag
    21901 ctccacctct ccatctgcaa ccaagagggc tgcgatagct gtcatcatgc cgatacggtg
    21961 gtcaccaaac gtattgactc tagcaccgtg aagagctgat ttccctttga taatcatccc
    22021 atctgccgta ggagtaatat ctgctcccat actatttaag gcgtctgcca caacctgaat
    22081 acggtctgtt tccttgacct tgagctcctc agcatccttg ataactgtta caccttgggc
    22141 ttgagtcgca agcagggcaa taatgggcaa ttcatcaatc aatcgtggaa tcaaagcgcc
    22201 accaatctct gttcctttca agtcagaaga ctcaacagtc aaggtagaag atttagcgac
    22261 tggatcgatt tcagttattt ccaattttcc acccatggca cgaatgacat caataatacc
    22321 ggtgcgagtt tcgttgatcc ccacattctg cagcactaga cgagaatttg gaacaatcaa
    22381 acctgcgact aaccaaaagg ctgcactgga aatatctcct ggtacgacca ccttctgtcc
    22441 tgtcaatttt tgtggccctt ggactgtgat tttcttactg tccacactta aatgaccacc
    22501 aaattgtttc aacatatctt cagtatgatt acgggtgcac tctttttcga taataactga
    22561 ctccccctta gcttgtaagg ctgcaaacat caaggctgac ttgacttggg cagaggcaat
    22621 tggcaactca taatgaatag gtcttaggtt tttcgtccct tttaagcgaa ggggaggcaa
    22681 gtctcgttca gtttgccctg aaatgctgac gcccattttt ttcagtggaa gggtcacacg
    22741 gtccatagga cgtttggaaa gactatcatc tccaaacatc tctacttcga aatctgcacc
    22801 agcaaggaca cctgaaatca ggcgaatcga ggtgccagaa tttcccatat taagggcatt
    22861 ttgcggcgct tttaagccag ccatgcctac accttgaatg gtaataaccc catctttatc
    22921 ctcaatttca acaccaaggt cacgaaaaac ctgcatggtc gaaagaacgt cttcacctcg
    22981 cagaatatca taaaccttgg tctcaccctc agccaaactt ccaaagataa tggaacggtg
    23041 gctgatagac ttgtcacctg ggacgcggat actaccatgt aaatggcgaa tatttgtttt
    23101 tagtttcata ctggacctca tacttgcaat acttttacct attttatcat aaaaagccag
    23161 aaattcctta aaaattcctg actttaggat cgttcttttc ttatttcagc aattctgaaa
    23221 ctggttcaaa aacaattttt tcaatgtcag aaaggtaaat ggccaattgt tgttgcttgg
    23281 taaagaattc tgacaagagg ctatttcctt gaatctgttt accaaagcct tccatcttag
    23341 cttggaagga cgcatctggc atttgacctg tctgtgctag tttttgaatt tcctcttgaa
    23401 aggcaagata ttccgtaaag attttgcttg cctcagcatc tgctgcaatc gcatctttag
    23461 ctgctttaac agccttgtat tctggtaatc cgcgtagacc gcgactgagt tcgtttgcac
    23521 tatcgtaaat atttgacatg ttcttctcct tatttgatga cgactgtata gtcggtattt
    23581 tctgttatga gatgctcagc tctttccaag tcttgagcat ttttaaatga aatttgtagg
    23641 attccgtgaa tatcctcacg attttcctcg ttgatgtgga tgttaaccaa ggaagttcca
    23701 cgtagcagtt ccaaaatccg caggatgaca tcttcttcat caggaacgtc aacatagagg
    23761 tcgtaagagc tatccacacc accacgctta tggatttcca tggtctggcg ttgttcacgc
    23821 gcttggttaa aaaagttcca aatttgctct tcatctccct tactaatggc ctgaccaatc
    23881 acttccaaac gttccttgaa atcctcaatt ctatccagaa tggtctcgct attggacaag
    23941 agaatggagg tccacattcc tggctcgctt tccgcaattc gggtcatatc tcgaaaacca
    24001 cctgccgcaa agcgccttgc catctcatgc tcttgagcat agaccgcagt ctgctccatg
    24061 agactagaag ccaaaatatg aggaaaatgg ctaatctgag aagtgacacg atcatgctcc
    24121 ttggcatcaa tctcgataaa acgagcatga agacctgaaa gcagatcctt catttcctta
    24181 agcgtgtcct gacttgtcag gcttgaaggt gtaaagatat aataggcatt ttcaaaaaga
    24241 ttgacatctg ccgaagcagc ccctgtcttg tgactaccag ccatgggatg ggccccgaca
    24301 aagcgaacag acttgccagc caaatactgc tccgccgcat ccacaatggt tgacttggtc
    24361 gaaccagcat ctgaaataat aacgccttct cgcaaatcca aattggccaa ctccttaatg
    24421 aaagcaatag tttgtttgat tggcaagctg aggataatga catctgccaa aggagcaaaa
    24481 ctagcaaaat catccgttgc acggtcaatc atgccttctt tcaaggcgat atctctcgaa
    24541 gcttgactac gattataacc taaaatttca taatctggat gatcgcgttt gataccaagt
    24601 gccatagagg ctccaatcaa cccaagacct gcgatataga ttgtttttgc cataggaact
    24661 ccttaatagt tctttgtata gtctcggtgt ttggctaccg cttcttttag ttcctcaaga
    24721 ttatctgatg agaatttttc gaggatttct tgcgccagaa ccgttgctac aactgcttcc
    24781 atgaccattc ctgcagctgg aagagcagtc ggatcacttc tctccacggt tgccttgtaa
    24841 ggttcatggg tttcgatatc cacactcata agaggtttat aaagagtagg aatgggtttc
    24901 atgaccccac gaacaacgat gggttgccca ttagtcatac caccttcaaa accacctaga
    24961 ttattggtac ggcgagtata accgtcttct ttagaccaga gaatttcatc cataacttgg
    25021 ctgcctttac gataaccagc ctcaaagcca agaccaaatt ccaccccttt aaaggcattg
    25081 atagagacaa cagcttgagc caatcttgca tccaattttc tatcccattg gacataggaa
    25141 ccaagaccaa ctggaacgcc tccgacgact gtctccacaa ccccaccgat ggtatcacca
    25201 tcacgtttga tttggtcaat atagtccttg atttcctgtt ctcgttcttg gttgacaata
    25261 gaaacttcag actgggcagc tctttgctta atttcagcga ctgtcagatt ttcaggaaca
    25321 tcgatttcct tgccaccaaa gaccacgaca tggttggcaa tctccatatc cagctcagcc
    25381 aagaggcgtt tggctactgc accaactgcc acccgcatgg tggtttcacg agctgatgaa
    25441 cgctccaaag aatttcgcaa atcatcaaaa cggtacttaa tccccccaac caaatcggca
    25501 tgacctgggc gaggatgagt aattttccgc ttgcttttaa gacggtcttc aatgtcctcc
    25561 gcagacatga tgtccagcca tttctggtgg tccttattga tgacatccat agtaataggc
    25621 gcccctgtcg tcttcccgtg gcgaacgccc gaagtaaaga caacctggtc attctcaatc
    25681 ttcatacgac caccacgacc gtagccaccc tgacggcgtc taaggtcctc attgatatcc
    25741 tcagctgtca atggaagtcc agctggaatt ccctcaataa tagctgttag acgggggccg
    25801 tgtgattctc ctgcagttaa atatctcata cactctcctt attttaccaa gtagtctttc
    25861 atctcttcca gagaaactgg atgaatggtc gctgaaccaa gctctggcac caagaccaat
    25921 ttcaaggtgt taccacgcgc tttcttgtca tgagtaagag cctgataaag cttgtcaact
    25981 tcccaatttt catagtcaac aggcaagccg aatttctgac acatctctgt gatagattgg
    26041 gtaatgctag ctggcatgag gcctttttcc tcagcaatct tggaaatctg taccattccc
    26101 atggcaacag cctctccatg catgaccttg ccataaccgg cagtcgcttc gatggcatgg
    26161 ccaatagtgt ggccaaaatt gaggtaaaga cgaataccat tgtccaactc atcttcaacc
    26221 accatcttgc gcttcacctg acaagaatgt tcaatcaagg tctctgcatg ttccaaaatg
    26281 ctctcaacag aaccattcag ccccgtcaag agagcccaca gttctggatc ctcaatcaag
    26341 ccatacttga taacttcacc catcccttca atcaactctc tttttccgag ggtttcaaga
    26401 acaagtggat caatcagaac cccatctggt tgagcaaagg tccccaccat atttttagca
    26461 aatggtgtgt taacgcctgt ctttccaccg atagaagaat caacctgagc tgtcaaacta
    26521 gtcggaatct gaacaaagtg aataccccgc atataggtag aggctacaaa gccagccagg
    26581 tccccaacaa cgccaccacc aagagccacg attccatcgc tacgagtcag accttgcttg
    26641 actagaaatt catagacttt ctgaacagta gttaaattct ttctttcttc accttctaag
    26701 aaatcaaaaa cagctacctg aaaaccagca tcttctaggc tgagcttgac cttctctgca
    26761 tagagagagg ctacatggtt atctgtcaca atgactacct tttgcggttg ccagagttct
    26821 cgcaaccact gaccagcctg ggccatacaa cctttttcaa tctgaatatc ataaggatga
    26881 tgaggaatat cgattctgat tttcatagga gagtctccct ttctttattg gtatttttct
    26941 gttaaagact gccaaatctc ttctgtcggc atttccttgc ctgtccacag ttgaaaagct
    27001 tctgcagctt gatagagcaa cattcccaga ccattgactg ctggattgcc ctgacttcta
    27061 gcccatttca aaaacggtgt ttcaaagggt tggtatatga tatctgcaac taagagagtt
    27121 tctggtaaga ctatgttttc aggaacagga gaggattggc catccatgcc cacactggtg
    27181 gcattaacta gcaaatccga ctcggcaatc cttgcttgca gttcagaaac atactctaaa
    27241 gcacacaaat ccactttaaa acctgtctgc tcctgtaact tgtctaggta aggtcttgtt
    27301 ttttccatag aaacggaacg aacaaagacc gaaatctgac tgacgccatc caaaatagcc
    27361 tgtgccaaga ttgatttagc cgcaccacct gcacccagca gggtcatctt tttacctgaa
    27421 attgtaaaag aaggcaagca cttaaaaaat cccttgccat ctgtattata tccaattaaa
    27481 ttgccattct cattgacaac cgtattaacc gcaccaatca agcgcgcttc atcgctcagc
    27541 ttatccaaat aaggaatcac ctgctcctta tagggcatgg acagattgat gccaaacatc
    27601 tggtagcgac gaatattggc cactgtttct gccaagtcac tcgcttcaat ctcccaagcc
    27661 acataagcac cgttggtagc tgtcgcctca aaggctctat tgtggatgaa gggagaaata
    27721 gaatgcttaa taggattggc aacaactgca gctaaacgtg tatagccatc aagcttcatc
    27781 caaaatctcc ctgatttttt tcatgctagc tagagaaatc tgcccagggg cactaacctc
    27841 atccagactg gcaaaagacc aactcgaacc agtcacatcc gcagtgatac gagagacctt
    27901 gcccacctta cccatagaaa tggtcacata ttcctgttca ggattgaggg ttttaaagcc
    27961 tcgtgtatag ttcatcaagt ctaagacatc ctgctccgtg tgagccatca ccgcaacctt
    28021 aacaagtttt ggatttagga tcgtcaactc tgacaagatt tccatcatgt tctcaggtgt
    28081 ttcttggaaa ttatggtaac tcaaaacaag atttgggaag tccagcattt cctcaaaaac
    28141 atccttgtag ctatagtact caaaatcaat atagtctggt tgatagaatt gcgcaacttc
    28201 cttgattaga tggatatact cttctggaga aaggtcgatt tctccacctt cggagcgagt
    28261 tcgtagcgtg aaaaccaact cacggcctgc gaatttttca aaaatggctg gagctacctg
    28321 caaaatcgct tctttaggca gatagtcggc acgccattca atgatgtcgg catccaggta
    28381 cctcgtggca tccagagcct gagcctcctc taaacttctt ggcattactg aaacgattaa
    28441 tttcatttac taaccttcat actaatcacc ttgaggtaat tactactttc atctttttta
    28501 ttataggcaa aatctgctgg aagaccatat ttgtttaaaa tctggtaact tcttcctgca
    28561 aagcctttat caatttgttc tgtaaatttc tgacgggaaa cattggcagc attggtactg
    28621 gcaatgataa tccctcccgg atttaaaatc tcaagactct gggaaatcaa cttgtgataa
    28681 tccttggcca cagagaaagt ttgtttttta ttccgagcaa agctaggcgg atctaggaca
    28741 atcacatcgt aggtcaagtc tttgcgtttg gcatatttga aatactcaaa gacatccatg
    28801 actataaaac gatgctcgtc tgtgctgagc ccatttgcct gaaaatgcgc ttgagacaat
    28861 tctcgtgaac gtttggctag atcaacagaa gttgtctggc tagctcctcc catggccgca
    28921 gctactgaaa aagccgctgt gtaggaaaac atattgagca aggatttacc catagccaag
    28981 ccgtcaacta aactaccgcg aacctcatgc tggtctagga aaattcctgt catcaagcca
    29041 tcattcataa agacttgata caggacacca ttttctaaaa cagtgaaaaa gtcaggtgct
    29101 tcttgaccat aaacatgggc agattcatag tcaaaaccct taaagcggat tttctcataa
    29161 gcccctaaaa cctcagggaa aacctgtcta aaggcttctg atatagtctg acgaatctga
    29221 taaacataag agttatacca agaaaagacg gcgtagtcgc cataaaggtc cactgtcaga
    29281 cccccaaagc catctccctc ttgattaaag agacgaaagg cagttgtcaa atcatcttga
    29341 tagtaagcgt ttctcttttc tttggctttt ctaaacaacg tttcaaagaa agtttgattg
    29401 aaggccacct tgtctttgct gacaaaccag cccaagccct tgttttgctg agaaaggtag
    29461 gcagtcccaa gaaagtttcc ttcctgaccc tgcacctcta cttcctgatc cttaagattg
    29521 acattctcaa gatcactgga ttctagtaaa actagcccct tagcaagctt cttttcaacc
    29581 cttttgctga ctcttattct atccataact accattatat caaactttta gacaattctc
    29641 aaaaaagaaa ctacccttgc ttttttactc ttcttttaaa aaatggtata ctagacttcc
    29701 tgcaaaacta ggaagtaaat gtgtaagaat cacaataaaa aatgctcttc catcttggag
    29761 gagcattctt tttatcaacg aaaatcaaat agcaaactat gaaactagcc tcaggttaac
    29821 cgtgagatta taggtagaga ggttgtatca gcaatatgtg tctgtcaaat ttagtgacaa
    29881 aggtagtaga agaaagatga agaaataaat ctgcttcaat aggtatctgg aaaatttgat
    29941 tttatagaga agccttttgt tacaaactca atatactatc aataaataat attatagaag
    30001 caacaataat tataatttca cctatctgca tcattctatt tcgaactcta aatatatgtt
    30061 ctatcaaaaa tacttggatc acacacatta taggaattaa cgtttttgaa attgaaaaat
    30121 atccaaataa ataaactata aacaacaata atagaactat attatatttc ttattcaaaa
    30181 cattcctccc tatatttttg attaccaatc ttaatcattt acaactacat tctaacaaac
    30241 tataaaagcg tttgtcgaat tgaatttatc aagcaagcaa ccaactatct catctttttt
    30301 ctatttctgc caatatgcgt gacaggtaat aatgatagcc aaaaatagca agagcaagca
    30361 agacgataag agctcctact cccaagttga tggcaaggat aggggagaga gactgaacca
    30421 agaatatgct cccaattaca agggccatca ggattgcact ataaataaac aataaaacta
    30481 tggcgactat gccatttgaa cgattcacca ggtccgtaat gctactccaa ttggttgaca
    30541 gatttttaac gtccttaaag taatggtggc aagaaaagat gacactggca atgatccaga
    30601 ctacaagaag gtaaatcatc gaaaggatgg acaagcctag atatagagaa agaccgagca
    30661 aagtcagaac tggtaaaaag gactgaacag caaagataat ccaaaatttc actttcacat
    30721 aacgagcaaa gtcaaagggt aaactcttca gaaaatcaac atttttcctc tccaaggaca
    30781 aggcaattga atgcaggctg gtgatattgt tattgacaac tgctataaac actcctacaa
    30841 aaaacaaggg taaccagtat ggaggatgaa tgtctggaac tatctgagaa tctcggattt
    30901 tggaaatcag actgatcatc atgagataag gaaggaaagc acttgtaaaa agcactgtaa
    30961 tcacgccagt cccctgtccc aagagggtga ggtggtagcg taaaaccata cggaaaaagc
    31021 cctttttagt agttgaaatc ctctccttgc tgcgacgttc ttttttgacc ttctcctcac
    31081 tgttaagcag gatcacgtca taaaaacgag gaaggacctt ctttttggtc aggtaaagca
    31141 agaaaacagt taaagctatc caagcgagca gacccaatat ggcttctatt gaaaaaggct
    31201 ccactgctat tttgtaaaag atatgaagag gataaaggag aaatggaatg tctctaactt
    31261 tgtcaacaat acttccaaaa gtcgactgta gaaagaagac aaatattaaa ggtatgagaa
    31321 ctcctatccc aatcatcaca ttcgaaaaaa tagactgata ctttctgaag gccgtagttt
    31381 gagccaagaa atgcactgcc actaccatca ctagagccac agagacaaat aataaggtca
    31441 aggacagtag catcaaaggc aaacccagcc aaagagaagg agctagacta atatagaggg
    31501 ctagaaaata agctaggatt ggtacaattc cagttagagc tggaaaaagg acagacagtc
    31561 ctttagcaat tataatctct gattctttaa aggcataggg cctataggag gccaggtcct
    31621 tactctcata aaagacattg taaaatgcag ttaaagaagt tgaaaaggca atcactagta
    31681 aaatagcaac cacgaaacta aaataaacag gcatttcctc aaaaggaaaa tgaatggcta
    31741 tagtactaaa aaagatgagc atcaagagac tggaaaaaat gtaagaactt aggactctag
    31801 cggaaacatt tacttttttt ccagtatttt tagcttgctt ctttcgtagg ttagccagat
    31861 tagcttctta agatgaatag aggatattga tatcaactaa ttttttaatg accttgagac
    31921 gcatctgaaa cctcctcttt tctaccagca aggctaaggt agatactttc caaagactgg
    31981 tctgggttgt cttttctcaa gtcctctacc ttaccacaat aaatcaaatg cccctttttc
    32041 aaaatagcaa tccgatcaca gacttgctca gctacctcta gcacatgagt tgaaaacaaa
    32101 actgtcttac ctttttgcgc atgctccttc atcatttgct tcaaatcaaa ggcagcctgg
    32161 ggatccaaac cagtcaaggg ttcgtccaag acccaaatat caggatcaga caagagtgcc
    32221 ccgatgacaa aaactttctg acgcattcca tgagaaaggg tttcaataac ctgataacga
    32281 ttttcagcaa aatcaaaaac gttcaataac ctagctaaac tagcttccaa gtcagagctg
    32341 ctcaaatcat aggatgaagc aatcaattcc caaaattcat tggccgttaa acgtaaaaat
    32401 aagtcaggcg agtctgctac gtagccaatc tttcgtttga tcgccaagcg attttccgat
    32461 aaatcctgac catctaccaa aatacgacca ctgctgggtg aaatgatact gactagggat
    32521 tttatggtgg tcgattttcc agccccatta tgaccaatca agcccataat ctctccattt
    32581 tcaatctgca aattgagatt actcaaggcc tctttatcac catacaactt actaacattt
    32641 tgaaattcaa tcatgggaca actcctatct ttatctgtat tatatatcgc tatactagca
    32701 ctttgataca aaaaaatcaa tactttattt taagtagtta aaatagtttc cttctatctt
    32761 acgcaaacgt ttgcgctaat agatacttta tgatagaata aagaacaaga ttgacaagta
    32821 agaggaaaca ttatgcaaaa tcaaacactc atgcaatact ttgaatggta tctgccccac
    32881 gacggtcaac actggacgcg tctggctgaa aatgctccac acctagctca tctggggatc
    32941 agtcacgtct ggatgccacc agccttcaag gcaaccaacg aaaaagatgt cggctatggg
    33001 gtctatgact tatttgactt aggagagttc aaccaaaaag ggactgtccg caccaagtat
    33061 ggtttcaaag aagactatct tcaagccatt caagccctta aagcgcaggg aattcaacct
    33121 atggccgatg tggttctcaa ccacaaggct gctgctgatc acagggaagc ctttcaagtt
    33181 attgaagtgg atcctgtaga ccgtacagtt gaacttggag aacccttcac catcaatggc
    33241 tggactagtt ttaccttcga tggtcgccaa gatacctaca atgacttcca ctggcactgg
    33301 taccacttca caggtacaga ctatgatgcc aaacgccgta agtctgggat ttatctcatc
    33361 caaggggaca acaagggctg ggctaacgag gaattggtcg ataacgaaaa cggaaactac
    33421 gactacctca tgtatgccga cctagacttt aaacatcctg aagtcatcca aaacatctat
    33481 gactgggctg attggttcat ggaaacgact ggtgtagctg gtttccgttt ggatgccgtt
    33541 aagcatattg actctttctt tatgcgcaac ttcatccgcg atatgaagga aaaatacggt
    33601 gacgatttct atgtttttgg tgaattttgg aacccagaca aggaagccaa tctggactat
    33661 ctcgaaaaaa cggaagaaca ctttgacctt gtcgatgttc gtctccatca gaatctcttt
    33721 gaagccagtc aagctggcgc aaactatgac cttcgtggca ttttcacaga tagcctggtt
    33781 gaactcaagc ctgacaaggc tgtgactttt gtcgacaacc acgataccca acgaggacaa
    33841 gcccttgagt ctaccgttga agaatggttc aagccagcag cctatgccct cattttgtta
    33901 cgccaagacg gccttccatg tgtcttttac ggagactact atgggatttc aggccagtat
    33961 gctcaagaag atttcaaaga aatccttgac cgcctcctag ccatccgaaa agatttggcc
    34021 tatggagaac aaaatgacta ctttgaccat gctaactgta tcggttgggt acgttcaggt
    34081 gctgaaaatc aatccccaat cgcagtcctt atctcaaatg accaagaaaa cagcaagtca
    34141 atgtttgtcg gtcaagaatg gactaatcaa acctttgtag atttacttgg taaccaccaa
    34201 ggtcaagtta caattgatga ggaaggttat ggacaattcc ctgtctcagc tagatccgta
    34261 agtgtctggg cagtcaatac catctaatag ctcataataa ccaagctagg tccaagcgga
    34321 tttggctttt ttgtattcac aaaaagacct acccaaatgg atagatcttt acttgattac
    34381 aatttacctg ctactgcatc caacaattct tggatcttag gttggttgct tcctcctgcc
    34441 atggccatgt ctggtttacc accaccacgt ccatcgatga ttggtgctaa ttctttgaca
    34501 aggtttcctg catgaaggtc ttttgtcttg cttgctacaa ggacattgac tttgtcaccg
    34561 atagcggcaa ctaggacaag aagatcagag tagtcttttt gtttccagtt atctgcaaag
    34621 gtacgaaggg cacctgcatc ggatacagac acttgactag caatgtaacg atgaccgttg
    34681 acttccttaa catctttgaa gatatcgcct gcggctgcag ctgcggcttt ttctttcaac
    34741 tcagcatttt ctttttgaag ttgacgaagt tgttcttgaa gtccttctac cttgtgaggt
    34801 acttccttga cttgaggtgc tttcaaggtt gctgcgacag ctttaagagc atcctcttgt
    34861 tcacgatagg cttcaaaggc ttccttacca gtcactgcca agatacggcg agttcctgaa
    34921 ccgattcctt cttctttgac aattttgaag agaccaatct cagaagtgtt gccaacatga
    34981 gtaccaccac aaagttcaat agagtagtca ccaatagtca cgacacgaac ttccttgccg
    35041 tatttctcac caaagagggc catcgctccc atttctttag cagtgtcaat atccgtttca
    35101 actgtcttaa cttcaagagc ttcccagatt ttttcgttga cttgctgttc aatcgcacgc
    35161 aattcttcag cagttacagc ttggaagtgg gtaaagtcaa agcgaaggaa ttcaacttcg
    35221 ttaagagatc ctgcctgtgt tgcgtggttt ccaaggatat tgtgaagggc agcgtgaagc
    35281 aaatgagtcg cagtgtggtt tttcatgaca cggtgacggc gattgctatc aattgccaag
    35341 gtatattctt ggttcaaggc aagcggtgca aggacttcaa ctgtatgaag ggcttgacca
    35401 tttggggctt tctgaacatt ggtcacagta gccacaacct tacctgactc atccaagatt
    35461 tgtccgtggt cagcgacctg tccacccatt tcagcataga atggcgtttc cgcaaagata
    35521 agtgaggtag ttccttctga tacagcttct acttctgcat tgtcagcaac gatagccacc
    35581 aatttagaag acaattggct agcattgtgg ttgaagacac tttctacagt gatgttttga
    35641 agagtttcat tttgcatacc cattgagcca cccttgacag ctgacgcacg cgcgcgttct
    35701 tgttgttctt tcatggctgc ttcaaaacct tcacggtcta cagtcatacc agcctcttca
    35761 gcaatttctt cagtcaattc aactgggaat ccgtatgtat catagagttt aaagacatct
    35821 tgaccagcaa tgacagattg acctttttct ttcaagtctg ccacaatgcc ttgggcaaag
    35881 tgttgacctg agtgaagggt acgggcaaat gattcttctt cgctcttaac gattttctca
    35941 ataaagtcac gtttctcaag cacttctggg tagtagcttt ccatgatttt tccaacagtt
    36001 ggaacgagtt tgtaaaggaa aggctcgttg atacccaatt tttgaccatg catagaagca
    36061 cgacggagaa gacgacgaag aacataacca cgaccttcat ttcctggaag ggcaccatca
    36121 ccgatagcaa atgaaagaga acgaatgtgg tctgcgataa ccttgaagct catgttgtcg
    36181 ccatcttggt cataaacctt accagacaat ttctcgactt cacggataat cggcataaag
    36241 aggtccgttt caaagttggt cttagcccct tggataacag ccaccaaacg ctccaaacca
    36301 gcgcccgtat caatgttctt atgtggcaat tccttgtatt cgctacgagg aacagcaggg
    36361 tctgcgttaa attgtgacaa aacgatgttc cagatttcaa tataacggtc gttttcaata
    36421 tcttctgcaa gcaggcgaag accgatattt tctgggtcaa aggcttcccc acggtcaaag
    36481 aagatttctg tatctggtcc agaaggtccc gcaccgattt cccagaagtt gtcctcaatt
    36541 ggaatcaagt gacttggatc cactcccact tcaatccagc ggttgtaaga atctttatcg
    36601 tctggatagt aggtcatgta aagtttttca gcagggaaat caaaccattc agggcttgtc
    36661 aaaagctcat aagcccaagt gatagcttcg tcacggaagt aatccccgat agagaagttc
    36721 cccaacattt caaacatggt atggtgacgc gcagtcttcc ctacgttttc gatgtcgttg
    36781 gtacggatag ccttttgggc attggtaata cgtggattct cagggataat ggtcccgtca
    36841 aagtatttct taagggttgc taccccagag ttgatccaca aaagagttgg gtcgtttaca
    36901 ggaaccaaac ttactgatgg ttctactgag tgacctttgg tcgcccagaa atcaagccac
    36961 atttggcgta cttgtgcact agatagttgt ttcatattgt ctccttattt acttgtttaa
    37021 tgtgattggc tttccagcat ttccacatag tcaatcgcga cacagaggga aatgactagg
    37081 tctgcataag cgtcctcaag aaccgttacg gtataggtag aggtcagatg gaagagttcc
    37141 ttcttaattt ccgcaatcag ctgatcgcga tcatccagca atttgaaatt caaatcccag
    37201 atattgccct cgatacgaag acctagatta tcaaactcat acttatctcg ccagaaggtc
    37261 aacttcttac gaatgacaaa actcgagcca tccctaagct gaatctcaaa acgaggaagc
    37321 aaggtcaaga tttctttact aatctcactg acttgttcac cagccgcatc atagatggta
    37381 aaggttttag gaatcttaaa aaatgatccc tccacctgat aggcaatttc tcccctgtca
    37441 tccttgatag cgaagcgttc gcctccaaga cgaaactttt gtttgacaag aaatgttttc
    37501 atcaacacct ccaaaaatca aaagacaagc tcatatcacg aagggcgaaa aaccgcggta
    37561 ccaccttcat tcaatgaact tgtcattctc ttgttcttat gcaattgtat gattgagtag
    37621 catgacttcc tagcttagat ggctcgcagc accgccattt ctctggacta agacaagtga
    37681 aaatcaattc tcaactttct tattataacg tttttttaag cttgcgtcaa ctggaaatga
    37741 tctccgttga attagaccaa ttccctacat ctctgattac tttttcagga tatatttttt
    37801 cttactgccg tttttctttt tatcccaaat tttcatatta ctaaacacag ctactagaat
    37861 atttccaaat ataaaggtgc ctatcaccca atatatggac tcagttgtta ggtattgtcg
    37921 atccaagcca tcctttaaat ggaatagtat aacagtttgg ttaacaatca taaaggttgg
    37981 ccagaaactt tttttgaaaa aagtagacat tttcattatt tgttgccgct ttctgtaagg
    38041 ttaatactca ataaaaatca aaaagcaaac taggaagcta gcctcaagct gtacttgagt
    38101 acggcaaggc aacgctgacg tggtttgaag agtataggct tagtatacta ctaggcaagc
    38161 aaataaacaa ataaacaact agaatagaaa aagatagggc tctaaaaact gacttctatt
    38221 ccttaaaaac gaaccagctt gactgattcg tcttcttacg tttatctcct acttccgata
    38281 cattttaaac tgtaggaaga ggtcgctata tttccctgtc catttatggt caaatttctc
    38341 ataaacttct aggtgtttca tggtttcaac atcgggatag aaggccttat cttcctttgt
    38401 ttcctctggg agcaattcct tcgctggtag gtttggtgtt gaatagccga catactccgc
    38461 attttggaga gcattttcag gtttcaacat aaagttgata aaggcatagg ctgagttttg
    38521 gtttttaact gttttgggaa tgaccatatt gtcaaaccaa agattgctgg cctctgtcgg
    38581 taccacataa cgtagatttt catttttttc taacatttgg ctggcttcac cagagaaggt
    38641 cacgccgatt gcaacattat tctgaatcat atagcccttc atctcgtccg caacgatagc
    38701 cttgatattt ggagtcagtt tgtagagctt atccactgtc tcttccaact gctgcagatc
    38761 cttggagttg aggctgtagc cgagggaatt gagccccaga cccagcacct cacgcgcccc
    38821 atcaaagagc atgatagaat tcttatactc cggcttccaa aggtcatccc aatgctcagg
    38881 cgcttcatct accatggttt cgttgtagac aattcctaag gttccccaga agtaagggat
    38941 ggagaattta ttacctgggt caaaggactg gttgagaaac tctggtccga tattttcgat
    39001 tccttcaatt tttgaataat caagcggaac caagaggtct tcgtccttca tcttgttaat
    39061 catgtattca cttggaatgg caatatcgta ggtcgttcca ccctgcttta tcttagtgta
    39121 catggcttcg ttggagtcaa aagtctcgta ctgaacttga attcctgttt cttctgtaaa
    39181 ctgagtcaag agttcaggat cgatatagtc tccccagtta tagataacca atttttgact
    39241 atctcgacta ttgattttac tatctaaatg agtcgcaatt ccccacaaga caaggataat
    39301 cgctgcaatt cctgctaaaa atgaatagat ttttttcatg cttgctcctc cttctcacga
    39361 gagataaagt aataacctac aactaggata atactaaaga gaaagactag agcagacagg
    39421 gcattgattt ctaaggaaat ccctttccgt gcacgagagt aaatctcgac tgacagggtt
    39481 gaaaagccat ttcctgttac aaagaaggtc acggcaaaat catccagcga ataggtgaag
    39541 gccatgaagt aacctgcaat gatagacgga gtcaggtaag gaagcatgat ttccttaaac
    39601 atctgaaatt gactagctcc caagtcatag gccgcatgaa tcatgtcgcc attcatttcc
    39661 ttgagtcgag gtaagaccat caagaccacg ataggaatgg agaaggccac gtgactagat
    39721 agaacggtca aaaagccaag tgaaaacttg agttgggtaa agagaatcaa gaagctagca
    39781 ccaatcataa cgtcaggcgc aaccatgagg atattattga gtgatagaaa ggcttcttgg
    39841 tatttcttac gagactggta gatgtaaatg gcaccaaaag tcccgataat ggtcgctatc
    39901 aaggctgata ggaaggccaa gaaaaaggtc tgagccaaaa tcagcatgag tctcccatct
    39961 ccaaacatgg tttcaaagtg agtccagcta aaacctgtaa agctattcat atcatcacca
    40021 gcattaaagg catagccaat caagtaaaag ataggcaggt agaggaccag aaagaccagt
    40081 cccagataaa ggttggcaaa ttttttcatc gttctctcct ttccttagtc acccacatgg
    40141 tgatgaacat ggtcaggatg agaatcacac cgatggttga acccatacca tagttgtcat
    40201 tggttagaaa attctgctca atagccgtcc ccaaggtgat aacgcggttc ccaccaatca
    40261 aacgggtcag catgaagaga ctcaaacttg ggataaagac cgactgaacc ccacttcgca
    40321 caccgttcat agatagaggg aagatgacat gacggaaggt ctcccactta gttgcaccaa
    40381 ggtcatagct ggcattgatg agattattat ccatatcgtc taagacattg aaaatcggca
    40441 aaatcataaa ggggagctcg atgtagcttg cgacaaagat aaaggaaaaa tcggtaaaaa
    40501 gcaactgttg tgaaccaatt ccgataaatt ccaagaattg gttaatagag ccattttgac
    40561 caaaaatccc gataaaagca taggctttaa ggagcaaatt gatccaggta ggaaggataa
    40621 tcagcatgag ccagagttga cggtgcttga gacgggtcaa aaagagggct gttggatagc
    40681 tgataagcaa ggtcacaaag gtcacaatcc ctgcataaag cactgagttg aaactcattt
    40741 taagataggt caagttttgt gacgcaaagt aagatttgta attttctaaa ctgaactggc
    40801 cttcgatgtt gaaaaaggat tgaccgaaaa tcaagaccaa gggtgccaat acaaagagcg
    40861 caatccaaag catgtagggt actacaaaga gtttagagct tgttttcttc atctctttcc
    40921 tcctcgattg cattgatcaa acctgcttct tgctcttcga tttctacgta ctcctcaata
    40981 cgagcatcga actcttcttc ggtttcattg agacgcatga tgtggatgtc ttctggttca
    41041 aagtccagac cgatttcctc acccacgatg gccttacggg ttgagtggat catccattca
    41101 tttccaagtt cgtcataggc gataatttca taatgcaccc cacggaagag ctgggtatcg
    41161 accttaactt gaagcttgcc ttcttcagga agggtaatgc gcaagtcctc tggacgaata
    41221 acgacctcaa caggttcatt tggcttcatc ccaccatcaa ccgcttcaaa gcgtttgccg
    41281 ttaaattcga ccaagtagtc ctcaatcatg gtacctggca agatgtttga ctccccgata
    41341 aaggtggcaa caaagtggtt gattggctca tcgtagatgt ccacaggggt tccagactgg
    41401 acaatctcgc catcattcat aacgaaaatc cagtcactca tggcaagagc ttcttcctga
    41461 tcgtgagtga caaagacaaa ggtaatgccc aatcgttgtt gcagttcacg cagttcgtac
    41521 tgcatgtctg ttcttaattt caagtccagc gctgacaagg gctcatccaa caaaaccaca
    41581 cggggttggt tgatgatagc acgggcgata gccacacgct gacgttgtcc tccagaaagt
    41641 ttgcggatgg aacgtttttc ataaccttcc aactgaacca tcttgagaac ttccgctaca
    41701 cgttgctcga tttctttctt atcaatttta cgcaagcgaa gtggaaaggc aacattttca
    41761 aacacattca tatgtgggaa caaggcatag gattggaaga cagtatgtac gtcgcgcttg
    41821 ttggttggaa tatcattgat acgaacaccg tctagcatga tatctcctgt cgtcgcatcc
    41881 agtaaacctg caataatgtt taggatagtt gatttccccg aaccagatgc acctagaagg
    41941 gtgtagaatt tcccttcttc caactcaaag ttgatgtctt tgagaacctt ggtgttgctg
    42001 tcttcaaaaa ctttagagac gtttttgaat tcgataattg gttttttcaa ttggcataaa
    42061 ttccttcttt ttcatagatt aaccgatcgg ggctctgtca ggtccccact acctcttgca
    42121 gggagtaaaa ccacctgcat acatcttcgc taccgatagg ctttcacccc cctttccatg
    42181 acatagcagc agcttttcaa atacagcttc ctacttgctt tcacccaaga tccggacttc
    42241 tctttcaagc gtaatacctg agtgttcctt gactttttcg ataaccgatt ggatcaagtc
    42301 ctcgtagtct ttggccgttc catctgcgac attgatcata aatcctgcat gcttttctga
    42361 cacttctacg ccaccgatac gatagccttt caagccagct tctgaaatta actgacctgc
    42421 aaaatgcccg actggacgct taaagaccga gccacaagat gggtattcca aaggttgctt
    42481 gagttcacgt aggtgcgtca agcggtccat ttcctgcttg ataacctgat gggttcctgg
    42541 ggctagggca aatttaactg acaagacaac tgcaccagac tcctgaatag ctgaatggcg
    42601 gtaaccaaaa gccaagtctt tagcagacag ggtttcgatt tctccatcct tggtcaagac
    42661 cttacaagac tgcaatatgt gagcaatctc gccaccatag gcacccgcat tcataaagac
    42721 agcaccgcca acgcttcctg gaataccaca agcaaactca aagccagtca aactatgacg
    42781 gagggcaatg cgagttgttt caatcaagtt agccccagct tctgcttcaa tggtatagcc
    42841 atcaacagaa acgttattga gcttgtcaca caagatgaca aatccacgaa tcccaccatc
    42901 acgaacgatg atattgcttg cattgccaag aaccatccaa gggatatttt cttggttggc
    42961 aaatttcaca acgcgagcca actcaaaacg atttcgtgga aagaccaaat aatcagcctc
    43021 tccacctact tttgtataac tatagctatg caagggttcc tgaaaacgga tatcaattcc
    43081 ttctaagatt tcaagcattt tttctcttac agacatgtca ctcttccttt tacaaaattc
    43141 attccattat accattttta gagacatttg acgaccataa aaataccttg tttggatttt
    43201 gcataagaaa aagaggttcc ccccttttta tgatttttta caaaagattt ccttggttcc
    43261 ataggcgacc agaacgagct ccagtgctag aatcacttca accaagactg gatttgtcaa
    43321 ccagcctact tgggaaagag atggtgccag atcaaagaag gcatgcaagc cataggcagc
    43381 taggagataa atccatttct tctggcgaac agcttggtaa acccaaactg tcaaaagtaa
    43441 ttggaaacca agcgccaaga ttcgctcaaa accaagcaaa taaatctgcc agaccgaaag
    43501 tgactgaatg gtttttaaca tattttcaga cagtaattgc ataacctgtg gattctgagt
    43561 ttgaactgtc gaaagaacga tgtaaagatt gagtaaacta gtaaggccta gaaaaatcaa
    43621 ctccaagcca ccatgcccta ggccataggc caaggcatct gccttttcca aacttctctt
    43681 tttctccaac catttgaaga aaacaagacg agccgtttcc tcaaaaaatg ctgccatggc
    43741 taggccatag ataatataga taagcggatg atcttgcaag agggcaatac taccgtcttt
    43801 ttgaggatgc aaaatcaaga tatgcaccag tttttccaaa atctgcgaag agacaaagaa
    43861 agcgactgca cccaagccca agacagctag attaatctgg tatttctttt tggcaaacca
    43921 aatgcttcct atcagaaaag ctagcaacag caacatggta ataatgatat gaatggtcat
    43981 tttcttctcc tattctgcct tttcaatatc ttttttcatc tcgtcaacat tgaacttagc
    44041 aaacaagtat tgacggtctt ggactgggaa acgttggtcc aactggtcaa ctgctcccac
    44101 ctcgataatg ccttccttga tgacaaaatc catgacatgt ccaccgaagg tcaaatcatc
    44161 tgagatgaag tgcagatggt agcctgccac actgacccca tggaaaatct caggcgtcca
    44221 gaaaccaaca atagtcccca caacattgtc acgactatat tccggttgat gggttgcgac
    44281 atcagcaaac ttggtatcgg gtgttgactt aggaatcata cgcacatgca tatgtgaaaa
    44341 ttctccccga atcttgatag agcggaaaag attttcccca tcataataag actcaattcg
    44401 ttcttccaat tccttgtctg tcatctcaaa gcgctggcgg aaaatgacct ctgcctgatg
    44461 cggtactact gctgcataag gaataagggc atctggtgac acttccacaa tttctggctg
    44521 ttctcctgtt ccttttgcct gataagcctt gccatctaag acaatcaatt ccccatcaat
    44581 agaatccaag gttcccaaac caaggtcacc atgctctagc aattctccca ctgtcatggt
    44641 accaccataa aggccagcca tcaaggctcc aagagtattg tattgaaata atttcactgg
    44701 ttcctgcacg ttcttatcca ttcactttct tgtctgttat tctataaatg ttactcctaa
    44761 gtataccaca tttgccccta gatgtgaacg agagaaacgc tctagacatt gccaagaagg
    44821 aaaaaaaagg gtacaatgta acaaaatcaa gggaggtctg gaatgaagaa acaaagcaag
    44881 tacaaagagg tcgtttccta tctgaaaaat ggtatcgagt ctggacgatt tccgacgggt
    44941 agtcgcctgc cttctatccg tcaactgagc cttgactttc actgcagcaa ggacaccatt
    45001 caacgagccc tgctggaatt acggcacgaa caatacctct atgccaagcc tcagagtggc
    45061 tactatgtat tagaacaagg gcaacatcaa gacctagaaa tcgaggttac cgacgaacat
    45121 gccagtgcct atgacgattt ccgactctgt gtcaatgaaa ccttgattgg ccgagaaaac
    45181 tacctcttca actactatga caatcaagaa ggattagaag acctaagaca gtccattcac
    45241 aaactcctct ttgagcaagc tctctactgc aaggctaacc aactagtact gacttctgga
    45301 acccaacaag ccttgtttat cctctctcaa atatcctttc ctagacaagc caaggaaatc
    45361 ttggtggaac agccaaccta ccatcggatg aatcgcctct tgattgcaca ggggctggac
    45421 tatcaaacga ttgaacgagg cattgatggg attgacttgg aggagctgga aggccacttc
    45481 aaaacaggaa aaattaaatt tttctacacc attccccgat ttcactatcc tctgggacat
    45541 tcctattctg agcaagacaa acgatctatt cttaacttag ctgccaagta tgatgtctat
    45601 atcgtagagg acgattatct gggtgatttg gactccaaga agggccaaac cttccactat
    45661 cttgatacag aggagcgtgt catttatatc aagtccttct cgaccagcct ttttcctgcc
    45721 cttcgtatta cagcactcat tcttccaaat gctatcaaag aagcatttgt ggcctacaaa
    45781 aatatcctag actacgacag caacctcatt atgcaaaagg ccctgtcact ctatattgac
    45841 agtcaattgt ttgaaaaaaa tcgtttggct cgcttgacca atcatgaatc ttaccaaaaa
    45901 caaatcgagg aaaggataac taaaacacct tgtccccttc ctcattatcc cctacacgat
    45961 ggtttattgc tagacctgag acagtatcct aaaatcgcca gtctcaaaca cagtcaactg
    46021 ggcttggact tctttgaaga ggcctattta agcacctgtc cttatcaatt tgccaaggtg
    46081 tccctagaca atctggaaaa tgttttaaac tatttaaaag cagaattgga atgacatcca
    46141 actctgcttt ttcttattct tcaacttcag ttagacttgc tgctttttca agatagcttt
    46201 ggtaagttcc ttcatcctta agtttttgga tgaccttgtc taccacttct ttcaaatcat
    46261 cactattttt tctaagagca acggcattgg cgtcgccgtc cttcatcttc aagctgacag
    46321 ttgcgacagc taagccagcg tttttagcag cataactaag tgcaacaggc tcatccatat
    46381 gaacagcatc tacttttcca gcctgcaatt cattgactgc ttcacccata ttagttaggg
    46441 aagttaattg agcttttggc aattgttcct tgaccattga ttctggaaca gtcccttttt
    46501 gggctgcaat attagcactt tctaggctag ttaaatcctt gtatttttcc acatcagcct
    46561 tacgaaccaa gaaactaatc ttgttttcat agtatgggat tgaaaaatca aagacttctt
    46621 ttctctcgtc agtagcacta attcctgcaa ctgctaggtc agccttacca gtttgaagac
    46681 tggtcaaaac attgtcaaaa ctcatgcttg agatttccaa cttaacccca agttcatcag
    46741 cgatagcctg agccatgtcg atgtctgcac cgactacctg gttctttcca tcaaccaatg
    46801 attgaaattc aaagggtgca tagtcaggac tggttgccac aactaatttc cccttttgct
    46861 taatggcctc aacagctgac tgagaaccat tagaacctga ctggcaagct actaagaaga
    46921 aacttgcaag aaaattacat aaaacaaata tccatttttt tgatttcata aataaacaac
    46981 ctctctgtta attttgtata attataacga tatccaagtt acttgtcaag tgttttttaa
    47041 atttttatct caaaaatatt ttttcgttca aaaaaaggag ccatcagttg atttcaagct
    47101 cctttttata cagaattaaa ctattttata attcgacaat cttacctgtt tcaaagtaga
    47161 caacccattc acagatattt ttagcatagt caccgatacg ctccaagtag gaaataactt
    47221 ggaaataatc acgacccgta acaatggctt ctggattttt cttaatctct tcagtcgcaa
    47281 ggtcacggat agtttcaaaa tagtggttaa tttgctcatc catggaggcc acccggtatg
    47341 catcgtcaac agaaccatta agataaagat caagtgctgc ttcaacaacg cttttaactt
    47401 cacgtcccat ttttttaatt tcttcctcta cagctgggat gcgttcttcc cccttcatac
    47461 ggatggttgc ctgggcaatg gctacagcgt gatcccccat acgctccaca tctgatacag
    47521 ccttaaggac agtcaagact gtacgcaaat cttgagagac tggttgttgg agtgcgatca
    47581 tttcaaatga tttcttttcc agtttcactt cgtattcatt tacttctgca tcatcttcga
    47641 tgacctcttt tgccaggtca cggtcatgcg tgacaaaagc acgtaccgta cgattgattt
    47701 gtgagagcac ttcttgtccc atagcgtaga actggttatg taatttctct aaatcttctt
    47761 caaattgaga tcgtaacatc tttcatctcc ttatccaaat tttcctgtaa tatagtcttc
    47821 cgtttccttg tgttggggat caaggaacat ctgcttggta tcattaaatt caatcaaatc
    47881 tccatctagg aaaaatcctg tcttatcaga gatacgtgaa gcttgctgca tggaacgggt
    47941 taccagaagc atggtgtact tgtcttttag accatacaag gtttcctcaa ttttaccagc
    48001 tgaaatcgga tccaaagccg aagttggctc atccaagagg atgattttag gactagttgc
    48061 caagacacgg gccacgcaga cacgctgctg ttgaccacct gacaatccaa tagctgaatc
    48121 atatagacga tccttgacct catcccagat agaggcacct tgcaaggctt tttctacggc
    48181 ttcatccaga acctgcttat ccttaattcc attgatacga agcccgtaga caacattctc
    48241 atagatagtc atagggaaag gattaggttg ttggaaaacc attccgattt ccttacgtaa
    48301 ttcaaccgta tctgtacgcg gactgtagat gttgtggcca ttgtacacca cggatccagt
    48361 tgtggtcacc tctggattga gatctcccat gcggttgaga gacttgagga gggttgactt
    48421 ccctgatcca gatggaccaa tcaaggctgt aatttcctta ggttggaaag atagggaaac
    48481 actattcaaa gccttctttt tattataata aacggacagg tctgatacct gtaaaatcgc
    48541 atctgtcata cggtttcctt tctaaccaaa gtgaccagat acatagtcat tggtggactg
    48601 tagcttggca ttttggaaaa tagttgcagt cttgtcatac tcaatcaaat cacccaagta
    48661 aaagaagcct gtatagtcac ttgcacgagc agcctgctgc atattatgcg ttacaatgat
    48721 gatggtaaag tttttcttga gctcaaacat ggtctcttct agttgcatgg tcgcaatcgg
    48781 atccaaggct gaggctggct catccattaa gaggatatct ggcttaacag agatggcacg
    48841 agcgatacag agacgttgtt gctgaccacc tgataaggtc aaggctgact tgtggagatc
    48901 gtctttaacc tgatcccaga gggcagcctg acgaagggag gtttctacga tttcatctag
    48961 gacttgctta tccttaactc cagcacgttc atgcgcaaag gtaatattac ggtaaattga
    49021 cttagcaaat ggattggggc gttgaaaaac cattccaatg tgtttacgca tttcataaac
    49081 gttgatttct ggacggttga catcaattcc acgatagaga atctgcccag ttactttagc
    49141 aatatcaatg gtatcattca tgcgattgag actgcgtaag taggtagatt tccccgatcc
    49201 cgacggacca atcaaagctg taattttatt tctttcaaat tgcatatcaa tccccttaat
    49261 ggattcattt ttaccatagt aaacatggac atccttagta gaaagggcta ctttttcttc
    49321 aggaaaggta aggatatgct tctcatccca gttatatgtt gacatggctt ctcctttagg
    49381 cagcggttaa tttcttgtgt agatagcttc cgaacttacg agctccaaag ttaaaaatca
    49441 ggataaagat caggagcaca gcggcagaac ctgctgatac aatggttcca tctggaatag
    49501 tgccttcact attgactttc cagatatgga cagccaaggt ttctgcttga cggaagatag
    49561 agatggggct agtcacactg aggatattcc agttagacca gtcaagagct ggcgccgatt
    49621 gccctgctgt atagatcaga gctgcagctt cgccaaagat acgaccagat gccaagacga
    49681 cacccgttac aatacctgga agcgcttctg gaataacaac atgaaccact gtctcccagc
    49741 gagaaatccc aagagccaga ccagcctcac gttgggtatg gtgaacgtgt ttcaaactat
    49801 cctctacatt acgcgtcatc tgaggcaagt taaagactgt caaggccaag gcacctgaaa
    49861 tgattgaaaa tccatactca aactggacta caaagatcaa gtaaccaaag agacccacca
    49921 ccactgatgg taaagaggac aagatttcaa tacaagtccg cacaaagttg gtaacaggac
    49981 cttttttagc atattcagcc aagtaaatcc cagctcccat agaaagaggt acagaaataa
    50041 tcaaggtaat gaccaatagg aaaaaggaat tgtaaagctg aatgccaatc ccaccacctg
    50101 cttgaaaagc agaagacctt ccagtcaaga aagaccaaga gatatggggc aagccccgaa
    50161 ccaagatata gagaatcaag gaagccaaga ttgtcacaat gatgctagca atcgtataga
    50221 ggacagctgt tgcaagttta tctaatttct tagcgcgcat aatttttctt tcctctttct
    50281 ttcgtaatca atttaatcac actgttaaaa actaaactca tcaagagcag taccaaggcc
    50341 agtgaccaga gaacattatt atttacagtt cccatgacag tgttcccaat tcccatagtt
    50401 aatatagaag ttaaagttgc agctggtgtg gtcaaggaag ttgggataac agctgagttt
    50461 ccgacaacca tctggatagc taaagcctca ccaaaggcac gcgccatccc aaagaccact
    50521 gcagtgaaaa taccagaacg ggccgccttc aagatcacac gccagatagt ctgccagcga
    50581 gtggctccca tagcgaaact ggcttcacga taataacgag gaaccgcacg caagctatcc
    50641 gttgtcataa aggttacggt cggcaaaatc atgacaaaga ggacggaaat ccctgacaaa
    50701 atcccaaaac cagtcccacc aaagacactg cgaacaaagg gaacgacgac ttgcaagcca
    50761 ataaatccat acactactga aggaatccca accaggagtt caatagctgg ttgcaaaatc
    50821 ttcgcccctt ttggtgatac ttcggtcata aaaactgctg caccaatagc aaagggtgtt
    50881 gcgataaggg ctgagagaat ggtaacgata aaggaaccca aaatcatagg aagggcacca
    50941 aattctttac tagaaggatt ccaagttcct cccaaaagaa agtcaaagat attcacacca
    51001 ttgacaaaga aggtcgacaa gcctttttgc gctacgaaaa ccaaaatcat ggccacaagg
    51061 atgactatca aagaaagaca ggcaaaggtc aaaccttttc ctaatttctc cagacgagaa
    51121 ttctttgatg gaagcaacat tttcttagct aattcttctt gattcattat tgtctccctt
    51181 ccaacactgt cacagttccg gcagcatctt tttcaacctt catttcctta atcggaatat
    51241 acttcaatcc tttgacaatc ccttcttggg tctcatccga gagaacaaaa ttgagaaatt
    51301 ctgcagccaa ctcattgggc tgccccaatg tatacatatg ctcataagac cacaagggcc
    51361 aattattgct acttatattt tctggactta agtcatagcc attcaacttc atgcttttga
    51421 ccgaatcatc tatataggta agagataaat aagagatagc tcctggactt tttgatacga
    51481 ttgattttac cgctccattt gaatcctgct cctgactttg catggcagac tgaccttcca
    51541 taatgacagt atcaaaggta gcacgagaac cagagccggc tgcccgattg ataacagaga
    51601 tgggtaagtc cttaccacca acctctttcc aattggttac ctcacctatg aagatttgac
    51661 gaagttgctc tgtcgttagg ttatcaacat caacctcctt attgacaatc agagccaagc
    51721 cagctaccgc gaccttgtgg tcaacaagag cagaagcatc aattccgtct ttttcctcag
    51781 caaatacatc tgagtttcct atatcaactg ccccagactg aacctgggac aagcctgtac
    51841 cagaacctcc cccttggaca ttgaccgttt ttccaacatg gatcgtgcca aattcatctg
    51901 ccgctacttc aaccaagggt tgcaaggcag ttgagccaac agccgttatg gattctccac
    51961 gatcaatcca gctagcacag cctactaaac aagccgtcag ccaaaaagcg ataagagaca
    52021 gagcaagctt ttttcttttt ttcactgttt ttctcctcga aaataattat gaatactgtg
    52081 aattttttaa gtagttcttt atgagttgac gcatgaattc ttaccaaatt tctgcgcaat
    52141 tgattattta tataatatag gctatattac tctttcctaa cctccttttt tcatatgtgg
    52201 ataaaatctc ttgtctatcc cttcccccat tgtcacccat tatagtcatt tcgtgtctct
    52261 ttttcccctt tttaatgcaa gggaaattac tctccttaga tgataatcca aaagctagaa
    52321 aggtatctca aacctctcta ctctcccaga ctagtttaca actaaaagga aaagattcta
    52381 ttttatgaga aatctagttt acaagcggta agaacgctaa taactaaact tcttgtactc
    52441 tttgaaaatc tcttcaaacc agtgttttga gctatctatg gctagcttcc tagtttgctc
    52501 tttgattttc attgagtagt aaaactacat gtaatggcaa tcaagatatc aagaatcatc
    52561 ctactaaaaa aatccatact ttcactataa catagaataa gatatttgac tagcattttc
    52621 atttgaatct gaggcctttt ggaaaataat ttttcaaaac atttccagta acctttgcaa
    52681 agcccaagcc attgccttta accaaaactt ggtaccaacc atttggcaga ctttctgcca
    52741 gctgaacgat ttctccagcc gcatacttga caaacgcttc ttggccaatt tcaaccgact
    52801 gttcgacctg actcggtttc aaggctaaac caagagcgaa actgggctca aagcgtttct
    52861 tcttaaaagt gcccagatgc agtccattgc gagcaatctt gagcttccct aaatctggca
    52921 aaagttctgg caagagataa agctggtctc caaaagtctg caagataccc ggtagattga
    52981 ccttcaaatg gttttgggca aattcctgcc acaaggcaac ttgttcacgg ctgaggttac
    53041 tcttacttgc cttaaattta ggagctggat tgttaccctt aaactgtaga tgggcaacaa
    53101 actgaccctc tcccttaaac tgatgaggat acatccgagc cgtttctggc aggtcaatac
    53161 cagctaccat tccattgata tgctctactg gcaacaagtc aaaatcatac tcttccagca
    53221 accaattgac aatctcttcg ttttcctcgg gtgcccaggt acaggtcgaa taaaccagat
    53281 gaccaccttc agctaacatg gtcactgcat cctccagaat ttctctttgc aagctagcac
    53341 attgactcgg ataatctaag ctccaatagt ccatagcatc aggttgctta cgaaacattc
    53401 cttcaccaga gcaaggggca tcaagaacga ttaagtcaaa atagccttta aagaccttga
    53461 ccaagcggtc ggcagattca ttggtcacca cgacatttgt cgctccaaaa cgctccatgt
    53521 tttcaaccaa aatcttagcc cgtttgcttg aaatttcatt ggaaacaagt agcccctccc
    53581 ctgctagata ggctgccagt tgagttgatt tgccccccgg tgcagcagcc aagtccaaga
    53641 ccttcatacc aggactgggt tgggctactt gagccaccat ttgagcagca ggttcttgcg
    53701 aataaactaa acctgtagca tgctcaggcg atttccctga aaccttccca tagtggcccc
    53761 aaggggtttg agtaatggca tcagaaaagg aaagttgctc ttcttttaag ggattgaccc
    53821 gaaaggccga aaccgcttcc tcctcaaaag aggcaagaaa atctcttgcc tcatctccta
    53881 gtatctcttt atatttttca acaaatcctt ctggaaattg catttaagtt cttttccttt
    53941 cgtaaatata ggactgaatt tcctcctgca tctcaagagg caccatcatg accggctgtc
    54001 tggtttgaaa atcaggagct tcaccaaaaa gggtcacaac ccgatagccc agactttccc
    54061 ctaaaatact agctgcggca taatcccatg gttgcagata agtgagatag gtcaacaaac
    54121 gccctgacaa aatcttggca aaactaatgg ccgcacttcc atagacacga acaccaagaa
    54181 ccgatcggct caaatcagcc agcccccatt cattggtttc cagcatacca ctattccctg
    54241 caatgagaaa atctccaagt ggtttagttt taaaaggagc tagggaccta tcatttagac
    54301 aaactggaaa ttccccacca ccgtggtaac aatccccttt gaccacatca taaatcagac
    54361 caaactgtcc ctgaccattt tcaaaataag ccatcataac agcaaaatct tcctgctggg
    54421 ctacaaaatt attggtacca tcaatgggat caatgaccca aaccttgccc tcttgaaccg
    54481 aggctcgcag acaaccttct tcagcacaaa tcttatcctc aggataacgg gacaaaatct
    54541 caccaaccaa gagttcctga acttctttgt ccagtctggt caccaaatct gttggagagg
    54601 acttggtttc aacacgcaag tcttcctgca tatggtcaag aatgtactga cctgctttct
    54661 taacaagctc tttagcaaat tcaaatttac tttccaagag aaatctttcc ttcccctttt
    54721 tctttggcag cctgaactgc tcggtaaagt gaatagccac taaccgtttc aaattctcgt
    54781 cccaaacgtt tctcttcgct cttgcttggc acgaccgctt tgaatccctt ataggagtcc
    54841 agtaactttt tagcctctac tttgccttca taggcagctt caacatcatt aaaaaaagaa
    54901 agcactgaag caagttcttc agtgctccac gacaaatcta gtgggtaact atactgtttg
    54961 ttcattaact aataccagct ctcattcttg cttcttttag ttcttgctta cgataactac
    55021 gagggagaaa agcacgaatc tcatcttcat taaaaccgat ttgcatacgc ttggcatcaa
    55081 taataattgg acgacgcaaa agactaggat actgctcaat caaatgaagc aattccgata
    55141 ccgaaatact ctctacatca atattcaatt tttgaaaaat ttttgaacga gttgaaatga
    55201 tgtcatcagt accattttcg gtcaaggaaa ggatgtgttg caattctttt cttgttaaag
    55261 gactggtcat aatattgtgt tccacaaagg gaaccttatg tttttctaac caggccttag
    55321 ccttacgaca tgatgtacag ctcggtgata gaaatagtgt aatcatgctt ttctcttctt
    55381 atctatactt tgctacttct attatacaaa aaaataaggc gcttgactag ggatttttag
    55441 aaaaaaagcc tattttttca ggaaaaatag gctgtttgcg aacgattgac acaattggat
    55501 ttggttaatt cactcttaac gatggtttta aacgatatgt atatatttat atatgtaaat
    55561 taaaaacatc tttcctttca cttcctacga cttttcagac acagatagcc aaagaagttt
    55621 tcatagaggg caaaaaagag gaggaaggca tgaagaaaga aggtctctgg caaaatcata
    55681 ataacaggat ccttggctgg atcaaaaagc caggtatcat ctcccacaaa gagaatttga
    55741 tggaaaagag taaagaattg gtcaaaacca atcaaaactc ccccaagtcc aatcattaca
    55801 ggtaaaacta ctagagccag gagacttttt cgataaagag acaaaaagtc ctttttcaca
    55861 atcctattga caaagacata gaaacttggc agtgtcacta gagctactag ctgaaccaaa
    55921 tgaaagagat tcttgaccac tgcgaaatgg tgcagaccag ctgctgacga acgaaaatca
    55981 ggcatctgta agacctgact aaaaggattg gtcagataat tcatcaagat atgaaaattg
    56041 tattgaatgg tttctggttt tagatagact cgattcgtta agtttagcca ctgaatctcc
    56101 ataggataga aaatccaagc cagataaatg gtcagaagga tggagaggga gaggagaaag
    56161 agcatagagc cccaaaagat caatttagtt ttcatcaaaa tcccactccg caaggctaga
    56221 aaccacatgt gtcggtgcga ttggcaggcc agctacttct tctgccttag taaaacctgt
    56281 cgtcaccaag agcgttggaa tgccattgtc aatcccagcc cgaatatcag tcaaataatt
    56341 gtccccaacc atgattaact cttcacgttc caaacctaag tgctcaaccg ccttgtccat
    56401 aatgatggca tttggttttc cgatataaac cggcttcact cgtgtcgcta cttcaagcag
    56461 cgtaatcagt gagccagcac ctggcaaaag accgcgttcc gtcgggatgt tgaggtcagg
    56521 attggttccg ataaaatggg cacccttttg aatagcaaga gttgctgtgg caaatttttc
    56581 atagtcgact tgccaatcca gaccaactac cacgtaggca ggtttttcct tgtcttccac
    56641 ataaccagcc gccttgatgg cttccttgag tcctgcttct ccgacgacat agacggtctt
    56701 ttcaagcccc aaatcattca tatagtcgat ggttgccaaa gtcgctgtgt agacagtcga
    56761 taggggcgta tcgatattaa aattctgagc caacatctcc ttaacactct ctggagtgcg
    56821 ggttgtattg ttggttacaa agagataggg aatgtcccgc ttttgcaatt catgaacaaa
    56881 agtctctcca gcagggattc ggtctttccc cttataaatg gttccgtcta aatcaattaa
    56941 atagccttta tatttcatct atttctccct aagccttttt tatttcttgc caagtaatga
    57001 ttgcttgggc attgataacc ccatcacttg taatttcatg cttgctttcc agtccagtcc
    57061 gttcaacagc cgatgtaatc accccacctg gtcgaacttc cttgacatac ttgaggttga
    57121 ttttcttggg aatatagtgg gtcaaaaaat ccgctcccat gacctcaaaa atccagtcca
    57181 agtatttact gttattgaca tgaccattca tatccaagtc gtaaaaacga acatggtaat
    57241 ccttgctgat cggttcttcc aaggactcat acttcggtcc acggataagt tttttatcaa
    57301 aatcagactg gtaaggagcc acaatctcag gttcaacaac atggactttt cgactgtcgc
    57361 ggtccatgag aacaaaggtc gccatcatgt ggatgagctc ctgctccgct tcattataaa
    57421 tagtaaagcg acggtagcaa aaaagtcgat tgtagctcaa ggcttccgtt tcgatggtaa
    57481 tttcttccgc aaaacgaggc aaacgaaaca cctcaatatc atattctacg ataatccaga
    57541 ccagattata ttcttccaaa atggccttat cactaactcc cagttcaatc gactgcatcc
    57601 ctgaaacttg cagtgacagc aaaatcacat ctggaagttt gatatgaccg ttcatatcag
    57661 ccatatcaaa aggaattttc attttcattt gataagttaa gcccatgatc ctactccaaa
    57721 ataaatcgtt ctgctacagt atctcccaaa aagagacctc tctttgtcat gcgaacgtgg
    57781 tcaccctcaa tctgcatgag gccttgttga accaaatctc tgacaatttc tccataaagt
    57841 ccagcaaaag actgtccaaa tttttcctca aatcgcgcca tggaaacccc ggatttcttg
    57901 cggagtccca agaacatttc ttcttccatt tgctcctttt gactcaggtg atcttctgta
    57961 atacaagcat tgccttcctc aaccgcactg agataatgac gaatgggacc atgattttta
    58021 tagcgtactc cattgacata accagatgcc cctgcaccaa taccatagta ttcagcattg
    58081 tcccagtaca tgagattatg acgactttca aagccgggtt tggagaaatt agaaatctca
    58141 taatgctcaa aacccgctcg ctccagctct gcaatgatgt actcaaacat ctccgcttct
    58201 agttcctcct taggcagagg caatttccca cgtcgcatcc ggttcataaa gaccgtatgg
    58261 ttttctaaaa tcaaactata caaactcatg tggggaatat ccaatccaat ggctttagcc
    58321 acattttcct ttacttgctc catggtctga ccaggcagag cataaatcaa atcaatggag
    58381 atgttgtcaa aaccagccag tttcaggcga tcgatatttt cataaatatc cttctccaaa
    58441 tgactgcgcc caatcttttt caacatctta tcatcaaagg tctggacacc tagcgaaaca
    58501 cgattgacag ccgaattttt caaaacagct atcttatccg catccaaatc gcctggattg
    58561 gcttcaatgg tcaactcttc caagacagac aaatccaagt ttttagtcaa gccattcagt
    58621 aacacctcca gttgcggagc cgacagggct gtcggtgttc caccaccgat ataaagggtt
    58681 gacaactttt caatatcata agaacgaaac tcttccagca gatgctctaa atagctgtcg
    58741 actggctgat ttttgatgaa gacctttgaa aaatcacaat aataacaaat ctgggtacaa
    58801 aatgggatgt gcacataggc tgacgttggt tttttctgca tagtaattat tataccacaa
    58861 agactagatt ccagataaaa atcaccatcc ccagatacat agtccgtccg gagatggtga
    58921 tggtttattc ttctgttata tcaatcacaa tctcttctga gtcatcaaga gcttcggctt
    58981 tttcttgcca ttgttccttg agattattta attgattttt tgatgcttct gtcgcttgaa
    59041 aagcatagga tttagcttga gcaagtatac tgtccacagt gatttcacct gactcaacct
    59101 gttcttttgt tttcagaaca aaatctgtag cctgctcctt aacttctgtc agtttttcac
    59161 agacttgctc cttggcatac tccggatctt ctctcaaatc atctagaaaa tcttgagcct
    59221 gactgcaaac ttgtttgccc ttatcacttg ttaaaaacaa ggcaagagct gcacctgaaa
    59281 cggttcctaa aaggattgag gataatttac ccataaggat tctccttttt tattttttga
    59341 aaaatttact tgcaagacga agagctgaca gacttgcacc agtcttgagt gtttttgaac
    59401 cagctgatga agctttcttg ctcaagacac gcgcatggtc attgaggtct gaaacagata
    59461 gagataaatc tgcaacagca ctgaagagtg gatcaatcgt agccaccttg acattgatat
    59521 catctgccaa gacattgacc ttagccaaca actcattggt gtgatgcaag gtcacatcca
    59581 catctgaagt caaggtttta atcgtctttt ctgtttcatc gatgacacga ccaagctttt
    59641 gtacagtaat gatcagatag accaaaaaga caatcacagc tagggcaaca agaatatatg
    59701 caacttctaa catttagttt tcctcctctg taatatagta aggggccttc tttcgatttt
    59761 gataaataac gatcattata ccgagaccga taaagacaac tgacagccat tgggacactc
    59821 gaaggccgaa gaacatgaga ctatctgttc gcataccttc gatgaccata cgaccgaaac
    59881 cataccaaat caagtaaaag gccgtgatat gacctcgtct gagactcttc catttccgtc
    59941 taaaaatcag aatcaaggca aagccaagca gattccatag agactcataa aggaaagtcg
    60001 gttgatggta gctcccctca atatacatct ggtcacggat aaagccaggt agataatcca
    60061 gattatccac tgttgcacca taagcttctt ggttaaagaa attaccccaa cgccccaaac
    60121 tttgagcaat cataacgcta ggcgccgcaa tatctagaaa atcccaagta ttgatgagtt
    60181 tacggtcagc aaagatatag agcacaagag ccccagttat caaaccaccg taaatggcca
    60241 aaccaccatt ccaaatggca aaaatctctc ctaaattctg actatagtaa tcaaatcgga
    60301 aaataacata gtagagacga gctcctaaaa tagccaaggg aaaggctact aagataaaat
    60361 ctaaaatatc gtctggtatg atcttctttc taggtgcttc tttcatggtc aaataaaccg
    60421 caagaatcaa gcctgtcaca atacataagg cataccaacg aatggctagg ggtcctagtt
    60481 gaatagcaat tggatcaagc attttgcacc tcatttcgag ctatgagact tgtcagtcgt
    60541 tcgtcgaaca aacgggtagc atcaaagccc atttccttgg cacgataatt catggcagct
    60601 gcctcaatca caacagagat attacgacct gttttaactg gaatacgaat acgaggaatg
    60661 gctacgccag aaacttcaag ttcctctgca ttgtttccaa gacgatcaaa ggtcttatgc
    60721 gtatcgtaat tttccaaata gacagcaagc tgaacctgtg aagaatcctt gacagcactc
    60781 gcaccgtaga gactcataac atcgataata ccaaccccac gaatttcaat caagtgtttc
    60841 aaaatttcag ctggttcacc ccagagagta atctcatcct tggcaaagat atcgacacgg
    60901 tcatcggcta ccaaacggtg accacgtttg acaagctcaa gacctgtctc gctcttacca
    60961 attccactat ctccctgaat caagacgccc atcccataaa tatccatcaa gacaccgtgc
    61021 acactggtac gttctgccaa acgagaatcc agatagctag ataactctcc agataaacga
    61081 ctggtagctg cacggctggt taaaatagca atcttacatt ctctagcagc ctttaacatc
    61141 tcctctggaa ccaccaaacc acgggcaaca atgactgctg gtgtctcagg tagaaacatt
    61201 tttttcaaaa cttcataacg gctgttggaa ggcatgctga tcagataaga ccactccttc
    61261 atccccaaaa gttgaatccg ctctggtgta tagtagtcaa aatagcctgt catttcaaga
    61321 ccaggtcgcg taatatccgc tgtattgatt tccttttcaa gcaattctgg ttcaccatag
    61381 acaatatcta gtctaagctt ttcaatcact tcttttacta aaaccgacat catttcctcc
    61441 ttcaaatgaa ttcttctctc tattatatca aattgtagga ggaagtttca gatttttgca
    61501 ggctttggag tatttattta aaagaaaaag gactagattt ctctagcctt tcatttcaat
    61561 tagaattttt tacgtttacg agctacttct gatttacgtt tacgttttac agaaggtttt
    61621 tcatagaatt cacgtttgcg tgtttcttga agagtaccag ctttagtaac cgcacgtttg
    61681 aaacggcgaa gtgcgtcgtc aagagattca ttcttacgta ctactgtttt agacattttt
    61741 ttcactccct tcaagttcaa tatctatttc attctacacg taaaaggaat aattgtcaag
    61801 caaaaatgcg gtttaatttt gattttttct tccatttata caagagttga aagcgttcaa
    61861 tagaacattg cttttttatt tttcgagtaa gctaagcgct tcagcatctg cgatgatggt
    61921 tacatcaggg tgattttgga ggctacttgc aggtaggttc tcagtcactg ggccagatac
    61981 tgttccggca atggcttctg ctttcgactc accataagca aaaagaataa tagacttggc
    62041 atccaaaatg tttttaatcc ccattgaaat agcttgggtt gggacgtctt caatcttggc
    62101 aaagaagcga gcattggctt cgatagtaga ctggtcaagt tctactagat gcgtttgact
    62161 gtcaaatgga gtaccaggct cattaaagcc gatatgccca ttgcgaccga ttcccaagat
    62221 ttggaggtca actggatggt cagccaaaat ttggttgtag cgttcaactt cagcttcagc
    62281 attgtcctta acaccacgag gcaagaaact ttctttaaat ggtttttggt tgaacaagtt
    62341 ttcttgcatg aagtaacgat aagactgtgg attgtcccca tcaaggccca catactcatc
    62401 aaggttgaca ctggttagat ttgaaaaatc aaggtcactc tcaacaattt ccttgtaaaa
    62461 ttcaagtggg ctacttcctg tcgcaagtcc tagagtttga gctccattag ccaatttttc
    62521 cttcaaaatc tcaaaagcaa cttttccacc ttgaacttgg ttttcaactt taataacttt
    62581 catcttttca tcctccattt ctgtctatat ttattatatg gtatagacca atttttgtca
    62641 agtgaaaacg atttaatttc taaaaaaaga gcgtccaaac ttgaaacgtg ttataatgga
    62701 taggattaga acttagaaag aatgaacaaa tatatgaata cagctgattt tgatttccac
    62761 ttgccagagg aattgattgc ccaaacgccc cttgaaaaac gtgatgcctc caaactcctc
    62821 atcgtcaacc gtgagacagg agaaatgcaa gataaacatt tccactctat tattgatatg
    62881 ctggaacctg gtgatgccct tgtcatgaac gacacccgag ttctccctgc ccgcctctat
    62941 ggtcaaaaag tggagacagg aggtcatgtg gaacttctcc tccttaagaa cactagtgga
    63001 gacgagtggg aagttctggc taaacctgcc aaacgcctca aggtcggtac tcgtatcagc
    63061 tttggtgatg gccgcctcag cgctgtcgtt acagaagaat tgacccacgg aggacgcatt
    63121 gtccgctttg aataccaagg aattttccta gaagtcttgg aaagtctggg agaaatgcct
    63181 ctgccacctt atatccacga aaaattagat gaccgtgaac gttatcaaac cgtctacgcc
    63241 aaggaaagcg gctctgctgc agcaccgact gctggtcttc acttcaccaa agaactgctg
    63301 gcagaaatcc aagctaaggg tgttcatcta gtctatctga ctctccatgt cggactcgga
    63361 acctttagac ctgtttctgt ggataatctg gacgaacacg aaatgcactc agagttctat
    63421 caactttctg aggaagctgc tgccaccctt cgctctgtca aaaaaaatgg tggtcgtgtc
    63481 atcgctgtcg gaaccacttc tatccgcacc ttggaaacta ttggttccaa gtttgatggg
    63541 caaatccaag cagattctgg ttggaccaat atctttatca aacctgggta tgagtggaag
    63601 gtcgtggatg ccttctcaac caacttccac ctgccaaaat caactctggt catgttggtt
    63661 tctgcctttg caggccgtga attagtctta gatgcctacc accattccat ccaagaacac
    63721 taccgcttct tcagttttgg tgacgccatg tttatttatt gagaaagaat ttctctaaat
    63781 cttctaatac caataaatcg ctaagatatt atttcaaaga acatctacaa ttgaaactct
    63841 agctaactgt agaagaggcc tagtacattg aaattaaaat gcttccccct agcttcgaaa
    63901 atattgccat agattgcgtt gactctccaa attgattcat ctatatttta tttcagcttc
    63961 ctatactttc ttcgctgttt gtaaatcaaa atgcaagaca catgagtagc accatatttg
    64021 ttactcttat ctgtcctctc aagagactat tatgagttat ttcagaatca ttcactactt
    64081 tgaccctgac tctccttagt ctcaaaatca aagacttata ctcttcaaaa atctcttcaa
    64141 accgcgtcaa cgtcaccttg gattatatat gtgactgact ttgtcagttc tatctacaac
    64201 ctcaaagcag tactttgagc aacctgcgac tagttttcta gtttgctctt tgattttcat
    64261 tgagtattaa acaaaaagtg aacaaatctg aattctaatg tacagaagac taggcttgtt
    64321 cactttttta tagtcgctat aagatgacct tatctatagc tttttatata taattatata
    64381 ttcagacata ctattatcaa ttttgtcgca gggaggaatc tgttaacgca cccattcacc
    64441 attatcattg actctatagc catctatact tgtattgacc gctaactcac ccgatgtatt
    64501 tacataatac catttaccac caacttggaa ccattgattg actttcatag aaccgttgct
    64561 gttgaggtag taccatgaac cattaacttg tacccaacct gttgccatgg aaccatcagt
    64621 attataaaaa taccacatac cattttcttg tttccagcct gttgttggag caactgcttt
    64681 agctggttct actgctacat ctgttccttg gttagatgta acagatacag gatacgaagg
    64741 aatagatgat tgctcaggaa caacaacttt ttcaggttct ctcgtccctc tccttatacg
    64801 tctttttacc atctctttag taatttgacg agaagtagtt tcttcaattg ttccatcacg
    64861 ttcatctaca gcatagattg tagtaagagt aattttacca atttctccta cttcttgacc
    64921 tttatcaaga gttgggtcat cgagatattc tgtttcgatt ggaatttctt ggacaataac
    64981 ttggggcttg gttccttttt taacaactct tgtttgagag tcttcttttt gacttaaagt
    65041 actctcagtt acttgtccac tctttccatc tacatcataa gttatcgttg taactgtttt
    65101 cccattcttt cctagagtaa tctcttgctc ctgtcctgca gaaaggtcat tgtctgcttc
    65161 atatttagta gcacatggaa caagaacttc ttcaaccttg cttttagctg gaactttgat
    65221 aactgtatcc gtggcttctt ttctatcaac agtaaccttt tcggtaacat gaccagtctc
    65281 tggattaaca tcgtaggtcc ttgtcgtggt tacatagcca tcctctccgt caattgtaac
    65341 aggattttca ctacggtatt ttgtttcatc tttttcaaaa cgaattcgcg tacttgaaat
    65401 tttcttggtt actaccttag gtttagtcgc tacttttaca ataatatccc cattgtcagc
    65461 gtcatcatac tctattccct cttctttatc tctagtatca tctctgacat attgaatccc
    65521 atcagcagca tgagcaaaac ttgtattcag attcctccta aaaataaagt tagcccgatt
    65581 accgcagaac caaaaatctt tccgagttta cgtattgcat agcgcttatt agtattagat
    65641 tttgccatta catcctactt ctagtatagc atcttttcta tcaaacgtta aacaatatac
    65701 tttatatata aaatagactt agaatgatat atttactatt gaactaacac tttaactata
    65761 tcgtaatcaa tctcatatat aaaggattgc agacatctga tctaaataca tgctaatata
    65821 tttagataca aacattccaa cttgataatt ttcactcatc tttcatcatt ccttacacaa
    65881 cgatgcagta taaatagaat agttttctca tcagaatgag actattttaa tattagataa
    65941 tttgatagaa aaaacataaa taaaattggt tgaatttaat tccctaactc gatagaggat
    66001 tctattttaa atttaacaac agctaggatt acactataaa aagtacatta ccacctgttc
    66061 ggctggagaa tctagtcgat tagctccctc ttagttacaa gcttaaagcg attttttaac
    66121 taatactaaa ccagattaaa gaaggaacta gaacatctgt cttgtactaa tcaatatgct
    66181 attttaaaat tgcaaataaa cttggaatgc taattattat atttacaata aatagttgac
    66241 ttcgatagaa acagaaaata gaattcaaca ttcttcccta cttataccat aataaataag
    66301 atccgcaaga tagccttttc tctctacacc attaacaatg gtttgtagat aggacattcc
    66361 agccttttcc atgacacgac ctgaagctgg gttgagactg gcataacgtg ctctgacctt
    66421 ttgaaaacct gcttgagtaa aacaaaagtc caagacagct ttcaaggcct ctgtcatcat
    66481 accatgtccc cagtaagcct tgcctagcac atagccgatt tcacagctta aatcagcctc
    66541 gtctatctta acgatgctga tatctcctat cacttgctct gggttttctt ttagacaaat
    66601 ggcccatttg taatagttga gattagtata ggaagcaacc caattgcgaa tcgagtttcg
    66661 agtgatttcg acatcaggat ggggatccca ggtaacatag gtcagattct cagcggatga
    66721 agcccaattt tgaaacatgg cttctgcatc actctccaca aatcttctta aaatcaaacg
    66781 ttctgtctgt aatatttgcg taccaataga tttcatgatg ctacctcact tccttatttc
    66841 tatgctcgta gtaaaaaggc tcaactcagt aacagctaga aaacgagttt gtcttctaat
    66901 ttcttgacgc agtcgctgcc tggtttgaaa tgcgatctag caagcttttt caaacctagt
    66961 catcgttgca ggggtaagac gatgaaatcg aactcttcga gttaccgaat ctgcctcatt
    67021 ttcttatttc taaactcgag gttcaagatc ccccggacct tctctcactt tcttatttca
    67081 agatgagagg ctgaaaacct ccagtggagg tttttcttgc tttttaattt cagggcaaga
    67141 agctaaaaag gtcccccgga cctttttact cccaaaagtc atcaaatacg gtgatgggta
    67201 agtggcgttt gtgttggcct ttgtgccacc agttttcaat ggtcgcttga gcttctgggc
    67261 tgattgtttt gccttctagg tagtcgtcaa tctctgcgta ggtgactcca agtgcgactt
    67321 cgtcagctag gcctggttta tcttcttcta ggtctgccgt tgggattttt tcataaaggg
    67381 ctggctctgc gccaagtttc tgcaagagct gttttccttg gcgtttattg aggcggtaaa
    67441 gagggagaat atccgcaccg ccgtcaccaa acttggtaaa gaaacctgtg atattttctg
    67501 cggcgtggtc tgttccaatg accgctccgc tatgggaacc agcaagggca tactgagcaa
    67561 tcatacggca acgtgccttg atattcccct tgttgaagtc tgaaacagga ctacctgtcg
    67621 cttcaactgc agctgtcatg gcatcagctg attccttgat attcacaacc aagctgacat
    67681 ctggctggat gaaggctagg gctttttgag catctgcttc atcagcttgc actccgtatg
    67741 gcaggcggac agcgataaat ttgtagctgt cgtctcccgt ttcagctcgc agttcttcta
    67801 tagctaattg cgccaaacgt cctgccaagg ttgagtcttg tcccccagaa atccctagta
    67861 caaaggtttt taggaaggga tgttttttca gatatctttt taagaaatca atagaacgac
    67921 ggatttcttc ctgggcatca atcactggtt tgacacccag ctcttggata atcgtttctt
    67981 gcaaactcat tcttcttctc cttcaccaag ggcttccttg cgcatcttat caatcaagtc
    68041 catcttatct tgccatacat cacgtgccaa atccactgga tagtgctgcg gattgagcac
    68101 acgcttatac tcatcccaca acttgtcaaa ttctttacgg gcataatcct gaatgtcagt
    68161 caaactaggc aagttgtaaa ctaatattcc ttctttgaag atatccacca agagaggaac
    68221 ggcatcaaaa ttacgaaccg tcttcttgat gtatgtatag gtcggatgga acatcttgat
    68281 ttctgtcatg tcgctaatat ccacaccatc ataagtgatg tagtcacctt ctgacttgcc
    68341 tttttcacga ctggtaatgc gccacacctg cttcttacct ggcgtcgaca ctttttccgc
    68401 attattagac agcttaatcg tattgcgcat ctgaccagtt tcatcttcaa ttgcaacaat
    68461 cttgtaaacc gccccaagag ccggctggtc ataggctgta atcagcttgg tacccacacc
    68521 ccagacatca atcttggcct tttgcatctt gaggttaagg atggtatttt catctagatc
    68581 attagaagca taaatcttag cctctgtaaa tccagcctcg tccagttgct gacggacttt
    68641 cttagaaatg taagcaatat ccccagagtc aatccgcaca cccataaagt taatctgatc
    68701 acccagttca cgcgccacct gaatggcagc tggtacaccg atgcgaaggg tatcataggt
    68761 atccacaaga aagacacaat ttttgtgggt cgcagcgtaa gccttgaaag cctcatagtc
    68821 attgccataa acctgcacca aggcatgggc atgggttccc aaaacaggaa tgtcaaagag
    68881 tttacccgca cgcacgttgc tggttccatt ggcgccacca atcaccgctg cacgtgttcc
    68941 ccagatggcc gcatccattt cttgagcccg acgtgtccca aactccatca agggttcatc
    69001 ttcgataacc gaacgaatac gagctgcctt cgtcgccacc aaggtctggt agttgacgat
    69061 gttcaaaaga gccgtttcga ccaactgaca ttgggctaga ggtccttcca cctgcacaat
    69121 cggttcatta gcaaaaacca aatccccttc ttgggcagaa cgaacggtca actccaactt
    69181 gaaattgcga aggtaatcca agaacgcccc atgataacca agcgactcca aataggctat
    69241 atcactatct gaaaaacgca agtcttcaag atagttcaca attctttcca aacctgcaaa
    69301 aaccgcatag ccgttcttaa aaggctgttg gcggaaatac acctcaaaga ccgccttctt
    69361 attgtgaatc ccttggtcaa agtaaacctg catcatgttg atctggtaca agtccgtgtg
    69421 caatgtcaaa ctatcatctg gatacatact tttcctactt ccttagctag aaacccatga
    69481 aaattttcaa gaactttcat gtattccaat aaattagtac tattatatca cattttagct
    69541 ggattgagaa aagagtaaca agctattctc cactctccaa ttcatccata tcttgttcaa
    69601 attttttctg agcccattcg ccatagctct taagaccaag attgccaata aagacccacg
    69661 gaaggtaaat gacataagta atgacccaag cagacaggta tttaaaattc aaaggattgt
    69721 gctgataaat ttctatgttg aattgataat tctgcaacat caaaagagcc gtaatagcca
    69781 aggttaggaa aaaacaaccc aaaatcgtaa aatgaaaacg actatagtag gtcactccca
    69841 gataacgggc acgattgaaa aagtaaaatg ttcctatgat gataacgatt agcagcatat
    69901 tagaattaaa aaggcttggt gctaatactg aaatgatata agataggagc gacaaagcga
    69961 tgcagatata gaaactttca gagcccgctt tattgaacag ttgttcttct ctttcgtcta
    70021 gtaattgata ataataaaat ctatttttca tcttcttcct cccaaaatag ttggtctagg
    70081 gttttcccta aacatctgca aatggactgg cagagcgaga gactgggatt gtatttcccc
    70141 gcctctatca aaccaatagt ctggcgcgtc accccgacag catctgctag ttgaccttga
    70201 gttaaatcaa gctctacccg agctaatttt aattttaaat ttttagccac cttcgtcctc
    70261 cttatagttt taatactcat ctactcttaa aaaatccaaa accaacacaa gctatcagct
    70321 atttattata accccattaa tttgcactcc agtattatct tcagccgaaa atcagtattt
    70381 taggttgttt gaaataaact tcctagttta ctcttttatt tttatttagt attagcttta
    70441 gtagaatctt ttaaacgagt ttttattgct tatatttctt gtttagttta gtt
//
LOCUS       DAVLGK010000005        64541 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLGK010000005 DAVLGK010000000
VERSION     DAVLGK010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64541
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.005"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..306
                     /locus_tag="VXE01_000376"
     CDS             <1..306
                     /locus_tag="VXE01_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0749362.1"
                     /translation="PEKPKPEVKPQPEKPKPEVKPQLEKPKPDNSKPQADDKKPSTTN
                     NLSKDKQPSNQASTNEKATNKPKKSLPSTGSISNLALEIAGLLTLAGATILAKKRMK"
     gene            complement(525..1505)
                     /gene="dusB"
                     /locus_tag="VXE01_000377"
     CDS             complement(525..1505)
                     /gene="dusB"
                     /locus_tag="VXE01_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV0749363.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKV"
     gene            complement(1492..2364)
                     /gene="hslO"
                     /locus_tag="VXE01_000378"
     CDS             complement(1492..2364)
                     /gene="hslO"
                     /locus_tag="VXE01_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV0749364.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2529..3956
                     /locus_tag="VXE01_000379"
     CDS             2529..3956
                     /locus_tag="VXE01_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0749365.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            4115..5623
                     /gene="glpK"
                     /locus_tag="VXE01_000380"
     CDS             4115..5623
                     /gene="glpK"
                     /locus_tag="VXE01_000380"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV0749366.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFESGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5665..7491
                     /gene="glpO"
                     /locus_tag="VXE01_000381"
     CDS             5665..7491
                     /gene="glpO"
                     /locus_tag="VXE01_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV0749367.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7561..8265
                     /locus_tag="VXE01_000382"
     CDS             7561..8265
                     /locus_tag="VXE01_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0749368.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8562..8765
                     /locus_tag="VXE01_000383"
     CDS             8562..8765
                     /locus_tag="VXE01_000383"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749369.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8852..9460)
                     /locus_tag="VXE01_000384"
     CDS             complement(8852..9460)
                     /locus_tag="VXE01_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749370.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGTGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            10559..11836
                     /gene="ltrA"
                     /locus_tag="VXE01_000385"
     CDS             10559..11836
                     /gene="ltrA"
                     /locus_tag="VXE01_000385"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEV0749371.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYFRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     YFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGFLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            12292..13470
                     /locus_tag="VXE01_000386"
     CDS             12292..13470
                     /locus_tag="VXE01_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0749372.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13784..13915
                     /locus_tag="VXE01_000387"
     CDS             13784..13915
                     /locus_tag="VXE01_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV0749373.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13936..15486
                     /gene="dltA"
                     /locus_tag="VXE01_000388"
     CDS             13936..15486
                     /gene="dltA"
                     /locus_tag="VXE01_000388"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV0749374.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15483..16727
                     /gene="dltB"
                     /locus_tag="VXE01_000389"
     CDS             15483..16727
                     /gene="dltB"
                     /locus_tag="VXE01_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV0749375.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQFLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16741..16980
                     /gene="dltC"
                     /locus_tag="VXE01_000390"
     CDS             16741..16980
                     /gene="dltC"
                     /locus_tag="VXE01_000390"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV0749376.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16973..18241
                     /gene="dltD"
                     /locus_tag="VXE01_000391"
     CDS             16973..18241
                     /gene="dltD"
                     /locus_tag="VXE01_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV0749377.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            18396..18836
                     /gene="adcR"
                     /locus_tag="VXE01_000392"
     CDS             18396..18836
                     /gene="adcR"
                     /locus_tag="VXE01_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV0749378.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18836..19540
                     /locus_tag="VXE01_000393"
     CDS             18836..19540
                     /locus_tag="VXE01_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0749379.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHNAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19533..20339
                     /locus_tag="VXE01_000394"
     CDS             19533..20339
                     /locus_tag="VXE01_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0749380.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            20349..21854
                     /gene="adcA"
                     /locus_tag="VXE01_000395"
     CDS             20349..21854
                     /gene="adcA"
                     /locus_tag="VXE01_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV0749381.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22983..23757)
                     /locus_tag="VXE01_000396"
                     /pseudo
     CDS             complement(22983..23757)
                     /locus_tag="VXE01_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
     gene            23933..25336
                     /locus_tag="VXE01_000397"
     CDS             23933..25336
                     /locus_tag="VXE01_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV0749382.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEGTAVGNIVVQLLSQGKINEDTELK
                     DIMTNIAETQYYYPQLS"
     gene            25365..26657
                     /locus_tag="VXE01_000398"
     CDS             25365..26657
                     /locus_tag="VXE01_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0749383.1"
                     /translation="MNKKSLLKCAVIGLVATFGLAACGTSKDASGGSSSGKEVLEFYH
                     GYHHSEDEWPVAKTMRDLYDKFAEEHKDSGVEFKPTPVNGDLKDIMNNKVASGEFPDV
                     IDLAGNAVSLVAIEQKLVLDLKPYIDSNKLEKNVGLNYKQNQKDGKIYTVHEQLFTMG
                     LWYNKDIFAKAGAKTPDQWNTWDDFTQAMASIRKQDGVYAFGAGEPSIRLFNTVLGTT
                     ENGRKLLDKPLTKEGIESKEFADALKMVMKEIQANGSKNAGGDANAYSKDFQEGKSAV
                     FFNGVWASGEMSKNPSLAPGIYPAGVAISSSGGGITISSKMSEAKQKLALEFLKYMTS
                     DDVQKVIFEKVGANPSNENVNVKELSEKSSEATTKILGQAITQVKNAKAVVPTVSDVW
                     GGDVQTAIINALTESAAENVDVDQKVKSTQDVLKSLIG"
     gene            26744..27673
                     /locus_tag="VXE01_000399"
     CDS             26744..27673
                     /locus_tag="VXE01_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0749384.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIFCINILFRERKRLKGGK"
     gene            27676..28515
                     /locus_tag="VXE01_000400"
     CDS             27676..28515
                     /locus_tag="VXE01_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0749385.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPTDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSCSGIAMSFFII
                     KNYFEIIPKELEEAAEIDGATYAQTFWKVMLPIARPGILTAAVLAFINNWNEYYWASM
                     LVIDKNELTVPALLGQFTTSFNTNYNGLFSAIVVIVLPPIILFAFTSKYFIEALGGGA
                     VKG"
     gene            28512..29831
                     /locus_tag="VXE01_000401"
     CDS             28512..29831
                     /locus_tag="VXE01_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0749386.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDSYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRDENTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            29837..31708
                     /locus_tag="VXE01_000402"
     CDS             29837..31708
                     /locus_tag="VXE01_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
                     /protein_id="HEV0749387.1"
                     /translation="MKIENKNVRRNFFWGDGRFYTTDIVNKRAGVMIKNVSKEEFTIT
                     LENGIRLSSNHFSAIVREEGDTRIQVSFVCPSIRLRLIFESRDDVLSKQLVLESSTEV
                     IKSVEVESFEFETEDNIFYPKRQDCIKEMANFSGYYVELGQPVYANSLFLGMEFPMSE
                     NKVDGRHYVSRYYLGTVVNQEKSLWSCIIGGACSYKKEEIQEAFFEYVEGIAQPSYFR
                     KQYNSWYDHMTDITEEGILKSFSEIRDGFENHGVHLDAYVVDDGWTNYQSVWEFNHKF
                     PNGLRNIKHLVNGFGSSLGLWIGPRGGYNGTEIIMSDWLEAHPELNIGSKNLISNDVN
                     VADFNYLNQMKKKMLEYQKEFDISYWKIDGWLLQPDKPDKSGPHGMYTMTAVYEFLIQ
                     LLIDLRKERGGKDCWLNLTSYVNPSPWFLQWVNSLWIQISQDVGFTENAGNDINRMIT
                     YRDSQYQEFLEKREIQLPMWSLYNHEPIYAVSANTWYMDHQMFASIPDFEAYLLFIST
                     RGNAFWEFHYSFDMFDEERWKANARAVKWIEENYQTLKYSKKIGGSPEKFEIYGYKCH
                     NQKTSTEILSLRNPAQIKQKIKIENLSIENFTRVIGDFTIQEDEIELAPYSIVILKK"
     gene            31730..33946
                     /locus_tag="VXE01_000403"
     CDS             31730..33946
                     /locus_tag="VXE01_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0749388.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCAETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEVYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLSTEKILDLAKAAKDLGIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADEIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSGRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYRSLLQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSGFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            33957..36974
                     /locus_tag="VXE01_000404"
     CDS             33957..36974
                     /locus_tag="VXE01_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEV0749389.1"
                     /translation="MESKKIAKQILIATAVLTSFLGSNLVYADVVQSNSNNRASTETA
                     RVTGNNLEKLIIKDKEIDKEMTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHT
                     KISLLTSDDKVKYFDKGIGTVADSPSVISYDISGQGFEKFETYIGIDQSANSSRSDHA
                     VVDRIEIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGD
                     EVVFADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPF
                     TPGNNGSNNKIKLLIDGKEVEFNKGLGTVASNPSSIKYDVSGANVTRFISYVGIDRSA
                     NHLNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIPKDTQTIELKSY
                     SGKHTWADELVLGGALFMANGKFKNPNDWSEVDKRREINNEHPLLMMPLYANGEEFNQ
                     GKYTFWGGDTLTGKWENIPDDLKPYTVIQLHPDDLPKRDGAARDFYEHMLEEAAKYVN
                     PKTGKNEPIPVILTVYTAGNMPYYTSAHWLSTSWIDKMYQKYPNLHGIFSTENYWIWA
                     NDIENKAADYLKVSAKNGGYFIWAEQNNGSAIEKAFGKNGKIAFQKSVDKYWKNLIFM
                     FKNTPAAEGNDSTTESYMKGLWLSNHTYQWGGLMDTWKWYETGKWKLFASGNIGKSQG
                     DRQWLTEPESMLGEEALGVYLNGGVVYNFEHPAYTYGVNNKESLLFSEVIKEFFRYVI
                     AHPAPSKEKVLEDTKVFIHGDYSNKGNGKFFVNVNTDREQTPLYMTGRYNVIPAIPGV
                     LKTDKLKESVSGSRIQIKEITSPEFSSTQARKEYLNKLYPMNYEGDIFAQKLDNRWFV
                     YNYKVNENVKQTGKLKFNSLEMDVEFEPHTYGIFERISNGLKVNLNNFRTNKDSLWSN
                     AQDANQAKKLPQLTKKGAIKWIEEHYIKDTQFGEKRVTKIVLRGIDKLPTIHSLSGTN
                     DSYDQPSLNFDQKNHMVNITINSNGNLEFELHF"
     gene            36989..37717
                     /locus_tag="VXE01_000405"
     CDS             36989..37717
                     /locus_tag="VXE01_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEV0749390.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIKMHIRCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVQSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            37730..39496
                     /locus_tag="VXE01_000406"
     CDS             37730..39496
                     /locus_tag="VXE01_000406"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV0749391.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            39642..40793
                     /locus_tag="VXE01_000407"
     CDS             39642..40793
                     /locus_tag="VXE01_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV0749392.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVANGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            40937..41821
                     /locus_tag="VXE01_000408"
     CDS             40937..41821
                     /locus_tag="VXE01_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0749393.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            42195..42446
                     /locus_tag="VXE01_000409"
     CDS             42195..42446
                     /locus_tag="VXE01_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0749394.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            42434..42753
                     /locus_tag="VXE01_000410"
                     /pseudo
     CDS             42434..42753
                     /locus_tag="VXE01_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(43159..44490)
                     /locus_tag="VXE01_000411"
     CDS             complement(43159..44490)
                     /locus_tag="VXE01_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV0749395.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAEDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(44512..46023)
                     /locus_tag="VXE01_000412"
     CDS             complement(44512..46023)
                     /locus_tag="VXE01_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV0749396.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(46232..47179)
                     /gene="arcC"
                     /locus_tag="VXE01_000413"
     CDS             complement(46232..47179)
                     /gene="arcC"
                     /locus_tag="VXE01_000413"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV0749397.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(47344..48360)
                     /gene="argF"
                     /locus_tag="VXE01_000414"
     CDS             complement(47344..48360)
                     /gene="argF"
                     /locus_tag="VXE01_000414"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV0749398.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(48418..49647)
                     /gene="arcA"
                     /locus_tag="VXE01_000415"
     CDS             complement(48418..49647)
                     /gene="arcA"
                     /locus_tag="VXE01_000415"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV0749399.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPVYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            50402..52081
                     /locus_tag="VXE01_000416"
     CDS             50402..52081
                     /locus_tag="VXE01_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0749400.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGACLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(52121..54205)
                     /locus_tag="VXE01_000417"
     CDS             complement(52121..54205)
                     /locus_tag="VXE01_000417"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV0749401.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEGGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDMATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTSFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKILVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            54376..55656
                     /locus_tag="VXE01_000418"
     CDS             54376..55656
                     /locus_tag="VXE01_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV0749402.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDEIF
                     VVATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKNFLLDQLVACDGGTGLMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            55747..58392
                     /locus_tag="VXE01_000419"
     CDS             55747..58392
                     /locus_tag="VXE01_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV0749403.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            58476..59345
                     /locus_tag="VXE01_000420"
     CDS             58476..59345
                     /locus_tag="VXE01_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0749404.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGVSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAATGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            59339..61219
                     /locus_tag="VXE01_000421"
     CDS             59339..61219
                     /locus_tag="VXE01_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0749405.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWSVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLQTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDHVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPNNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTNFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            61509..61871
                     /locus_tag="VXE01_000422"
     CDS             61509..61871
                     /locus_tag="VXE01_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749406.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(61941..62647)
                     /locus_tag="VXE01_000423"
                     /pseudo
     CDS             complement(61941..62647)
                     /locus_tag="VXE01_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(62592..62774)
                     /locus_tag="VXE01_000424"
     CDS             complement(62592..62774)
                     /locus_tag="VXE01_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0749407.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            63043..>64541
                     /gene="pcpA"
                     /locus_tag="VXE01_000425"
     CDS             63043..>64541
                     /gene="pcpA"
                     /locus_tag="VXE01_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV0749408.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGS"
BASE COUNT        19810 a        11623 c        13888 g        19220 t
ORIGIN      
        1 ccagaaaaac caaaaccaga ggttaaaccg cagccggaaa aaccaaaacc agaggttaaa
       61 ccgcagctgg aaaaaccaaa accagataat agcaagccac aagcagatga taagaagcca
      121 tcaactacaa ataatttaag caaggacaag caaccttcta accaagcttc aacaaacgaa
      181 aaagcaacaa ataaaccgaa gaagtcattg ccatcaactg gatctatttc aaatctagca
      241 cttgaaattg caggtcttct taccttggcg ggggcaacca ttcttgctaa gaaaagaatg
      301 aaatagtgat tgattcattc aaaaatgttt gtaaaaagta ttcggcttaa aagaaaagag
      361 tctgggataa aaagattttg attttaggaa ttctttatta taaattttta aaatcgatag
      421 attagacaaa aaagcgaaca agacagaatt ctgagtgtca gataactgat tttgttcgct
      481 ttttatattt aatattatac ttttgtccta ggctcttttt tgcattatac tttttccaat
      541 tgcaagagag cttcaatctc tgctagggtg ctagcttgcg aaatggctcc acggagtttg
      601 gcagcgccag atgttccacg gagatagtga ggagcgaggc cgcggaattc acgaactgcg
      661 acgttttctc ctttgaggtt aatcaatcgt ttcaagtgtt cgtaggcgat cttcatcttg
      721 tcttcaaatg tcaaatcagg taggatttct cctgtttcaa agtaatggtt gatttggttg
      781 aagaggtaag gatttcccat ggcagctcgg ccaatcatga ctgcgtcagc accaacttct
      841 tcgatgcgtt gcttggcttc ttggacagta cggatatcac cgttggcgat gaatggaatc
      901 ttggttagag cttgggcaac cttgtaaagg gtctcaaggt ccgcgtggcc agtatacatt
      961 tgttcacggg tacggccatg catggcgagg gcagaaacac ctgcagcctc agcagcgagg
     1021 gcattttcta ctgcaagaga tgggtccgcc cagccggtac gcattttgac agtaagtggg
     1081 atatcaagga cagactggac cttgttgatg atagagtaga tcttgtcagg atccttgagc
     1141 cacatagcac cagcttcgtt cttcacgatt ttgttgacag ggcagcccat gttgatatcg
     1201 acgatatcgg tcttagtgtt ttcttggata aattctgctg cgcgtgctag gctgtcttca
     1261 tcgctaccaa aaagttggat agagacaggg ttttcgccct catcgatatg aagcatgtgc
     1321 agggtttttt cgttgttgta ttggattccc ttgtcagaga ccatttccat tacaacgagt
     1381 ccagctccga gctcttttgc gatggtacga aaggctgagt tggtcacgcc agccataggc
     1441 gctaaaacgg tacgattggg aatctcaaca ttgccaatca taaaaggtgt attaagattt
     1501 gtcacgaatg agttcctcca ggtccttttc atcaaagttg taagtagttt ggcagaattg
     1561 acaagtgatt tctaccccgt ggtcttcctc tttcatttcc tgtaagtctg agcttggaag
     1621 gctggcaaga gcgttcataa agcgttcatg gctacagtca cattggaaac ggatttcttc
     1681 ttcagaaaga cgcttgtagg cttcgtcccc gtagatagcc ttgaggaggg cttcgatatg
     1741 gtcgtcgctt tcgagaagag tagagatagc tggcatttct tggatgcgtt tttcaaagcg
     1801 agcaatctct tctttcttgg ctcctggcaa gacttgaact aggaaaccac ctgcaatctt
     1861 gaccttgtct tcctcgtcca aaaggacatt gaggccgacc gctgaaggcg tttgttggct
     1921 ttcagtaagg taaaaggcaa ggtcttcacc gatttctcca gagatgaggg gagttataga
     1981 gttgtaagga tttccagtac cgtagtctgt gataacgagg aattgaccat ttccaacaaa
     2041 aggtccgact aggacttcac cagtcgcagt ctttttgatg tcaacaccag gattttgaac
     2101 gtagcctttg acgttcccct tggtatcagc gacggtgata atagcaccta gagagctaga
     2161 tcccaacacc ttaactgtaa gtttggtatt tcctttttca ttggctgcga gaatctggct
     2221 ggcgataaga gttcgaccaa gcgctacagt tgagctagct tgggtttgat gtttttcttg
     2281 agcagtgcgg acggtttcag tgctatcaag gacaaaagca cgaaaggctc cgctttctga
     2341 tatagtttta ataattttat ccatagctac tattttagca taaaaatgcc caaaggggga
     2401 gccgtgtgtt tactgatttt caggataatg gaccaggaaa tcagcatgaa aataaaaaga
     2461 gaaacagatt attttagcat ttgtaagatt tatgctatgc ttaaggtaga aaatgaaagg
     2521 ggtaacaaat gtatttagga gatttgatgg agaaagccga gtgtggtcaa ttttcaatcc
     2581 tttcctttct attacaagag tctcagacga ccgtcaaggc tgtaatggaa gaaacaggat
     2641 tttcaaaagc aaccctaacc aaatatgtca ccctgctcaa tgacaaggct ttggatagtg
     2701 gcttagagct gactattcac tcagaagatg aaaatctgcg tctgtctatc ggtgcagcta
     2761 ccaaggggag agatattcgg agcttgtttt tggatagtgc tgttaaatac cagattttgg
     2821 tttatcttct ctaccaccaa cagtttttag cccatcagct ggctcaagaa ttggtgatta
     2881 gcgaggctac gcttggtcgt cacttggctg gtttaaatca gattttgtca gaatttgatt
     2941 tatccatcca aaatggacgc tggagaggtc cagagcatca gattcgctat ttctatttct
     3001 gtcttttccg aaaggtctgg tcgagtcagg aatgggaagg tcacatgcag aaaccagaga
     3061 gaaaacagga gattgccaat ttagaggaaa tctgcggtgc aagtttgtct gcggggcaga
     3121 aattggactt ggttctctgg gctcacatca gtcaacaacg tcttcgggtc aatgcttgtc
     3181 agtttcaagt catagaagag aaaatgcgag ggtattttga caatatcttt tatcttcgtt
     3241 tgctgagaaa ggttccgtcc ttttttgctg ggcaacatat tccactagga gttgaggatg
     3301 gtgagatgat gatattcttc tcttttctcc tatctcatcg cattcttcct cttcatacta
     3361 tggagtatat tcttggtttt ggagggcagt tggcagattt actgacgcaa ttgattcaag
     3421 aaatgaagaa ggaggaacta ttgggggatt atacagagga ccatgtcacc tatgaactca
     3481 gtcagctttg tgctcaagtc tatctctata agggctatat tttacaggat cgctacaagt
     3541 accagttaga gaatcgtcat ccatatttac tgatggaaca tgattttaaa gagacagcag
     3601 aggagatttt tcatgctctg cctgcttttc aacaggggac agatttagat aagaagattc
     3661 tctgggaatg gctccagtta atcgaatata tggctgaaaa cggtggccag catatgcgga
     3721 ttggtctgga tttgacatct ggttttcttg tcttttcaag gatggcagcc attttgaaac
     3781 ggtatttgga atacaatcgt tttattacca ttgaagctta tgaccctagt cggcattatg
     3841 atttgctggt taccaataac ccgattcata agaaggaaca gacaccagtc tattatttaa
     3901 aaaacgactt ggatatggaa gatttggcag ggattcgtca gttattattc acttaaaagg
     3961 cttggttaat ccaggtcttt tttgtgaaat tcacacaatc tcctcacatt tttttaaaaa
     4021 ttaaaaaaag ttgataaaca agaaagcgct ttattttgta tactagtaag tgtaaagagg
     4081 aaacacctca agatctttat caggaggaca gtacatgtca caagaaaaat acatcatggc
     4141 cattgaccag ggaactacaa gttctcgtgc catcattttc aacaaaaaag gggaaaaggt
     4201 tagctcgagt caaaaagagt ttacccagat tttccctcag gcaggttggg ttgagcacaa
     4261 tgccaatgaa atttggaact ctgttcagtc agttattgcg ggtgctttca tcgaaagtgg
     4321 tgtcaagcca aatcaaatcg aggcaatcgg gattaccaac caacgtgaaa caacggttgt
     4381 ctgggataag aaaacaggac ttcctatcta caatgctatc gtttggcagt cacgtcagac
     4441 agcacctttg gctgagcaac taaaaagcca aggttatgtg gaaaaattcc atgaaaagac
     4501 tggtttgatt attgatgctt acttctctgc taccaaggtt cgttggattt tggatcatgt
     4561 agaaggtgct caagagcgag cagaaaaagg ggaattgctc tttggtacta tcgatacttg
     4621 gttggtttgg aaattgactg acggtgcggc tcacgtgact gactactcaa atgcagctcg
     4681 taccatgctt tataacatta aagaactcaa atgggatgat gagattttgg aaatccttaa
     4741 cattccgaag gctatacttc cagaagttcg ttctaactcc gaaatctacg gcaagacagc
     4801 tccattccat ttctacggtg gagaggtgcc aatctcaggt atggctgggg accaacaagc
     4861 agccctcttt ggacagttgg cttttgagtc aggtatggtt aagaatactt atggaacagg
     4921 ctctttcatc atcatgaata ctggggaaga gatgcagttg tctgaaaaca acctcttgac
     4981 aaccattggt tacggaatca acggtaaggt ttattatgcc ttggaaggtt ctatcttcat
     5041 cgcaggaagt gctattcagt ggcttcgtga cggtcttcgc atggttgaaa attcaccaga
     5101 atctgaaaaa tacgctcgtg attctcacaa caacgatgaa gtttatgtcg ttccagcctt
     5161 tacaggtcta ggcgctccat actggaacca aaatgctcgt ggttccgtct ttggtttgac
     5221 tcgtggaaca agcaaagaag actttatcaa ggcgactttg caatctattg cttatcaagt
     5281 gcgtgatatc atcgacacca tgcaagtgga tactcagacc gccattcaag tactgaaggt
     5341 ggatggtggt gcagccatga acaacttcct catgcagttc caggcggata ttttaggcat
     5401 tgatattgca cgtgctaaaa acttggaaac aacagctcta ggagcggcct tcctagcagg
     5461 tttatcagta gggtactgga aagacttgga cgagttgaaa ctcttgaacg agacaggaga
     5521 actctttgag ccatctatga atgaatctcg caaggaacaa ctctacaagg gctggaagaa
     5581 ggctgtgaaa gcaactcaag tctttgcgga agtagacgac taatactggc agaataaagc
     5641 gatttattta gaaagtgtgt aaatatggaa ttttcaaaga aaacacgtga attgtcaatt
     5701 aaaaaaatgc aggaacgcac cctggacctc ttgattatcg gtggaggaat cacaggggct
     5761 ggtgtagcct tgcaggcggc agctagcggt cttgagactg gtttgattga aatgcaagat
     5821 tttgcagaag gaacatctag tcgttcaaca aaattggttc acggaggtct tcgctacctc
     5881 aaacaattcg acgtagaagt ggtctcagat acggtttctg aacgtgcagt ggttcaacaa
     5941 atcgctccac acattccaaa accagatcca atgctcttac cagtttacga tgaagatgga
     6001 gcaaccttta gcctcttccg tcttaaagta gccatggact tgtacgacct cttggcaggt
     6061 gttagcaaca caccaactgc gaacaaggtt ttgagcaaga aagaagtctt ggaacgccag
     6121 ccaaacttga agaaggaagg cttggtagga ggtggagtgt atcttgactt ccgtaacaac
     6181 gatgcgcgtc tcgtgattga aaacatcaaa cgtgccaacc aagacggtgc cctcattgcc
     6241 aaccacgtga aggcagaagg cttcctcttt gacgaaagtg gcaagattac aggtgttgta
     6301 gctcgtgatc tcttgacaga tcaagtattt gaaatcaagg cccgtctggt tattaataca
     6361 acaggtcctt ggagtgataa agtacgtaat ttgtctaata agggaacgca attctcacaa
     6421 atgcgcccaa ctaagggagt tcacttggta gtggattcaa gcaaaatcaa ggtttcacag
     6481 ccagtttact tcgacacagg tttgggtgac ggtcgtatgg tctttgttct cccacgtgaa
     6541 aacaagactt actttggtac aactgataca gactacacag gtgatttgga gcatccaaaa
     6601 gtaactcaag aagatgtaga ttatctactt ggcattgtca acaaccgctt tccagaatcc
     6661 aacatcacca ttgatgatat cgaaagcagc tgggcaggtc ttcgtccatt gattgcaggg
     6721 aacagtgcct ctgactataa tggtggaaat aacggtacca tcagtgatga aagctttgac
     6781 aacttgattg cgactgttga atcttatctc tccaaagaaa aaacacgtga agatgttgag
     6841 tctgctgtca gcaagcttga aagtagcaca tctgagaaat atttggatcc atctgcagtt
     6901 tctcgtgggt ctagcttgga ccgtgatgac aatggtctct tgactcttgc tggcggtaaa
     6961 atcacagact accgtaagat ggctgaagga gctatggagc gcgtggttga catcctcaaa
     7021 gcagaatttg accgtagctt taaattgatc aattctaaaa cttatcctgt ttcaggtgga
     7081 gaattgaacc cagcaaatgt ggattcagaa atcgaagcct ttgcgcaact tggagtatca
     7141 cgtggtttgg atagcaagga agctcactat ctggcaaatc tttacggttc aaatgcaccg
     7201 aaagtctttg cacttgctca cagcttggaa caagcgccag gactcagctt ggcagatacc
     7261 ttgtcccttc actatgcaat gcgcaacgag ttggctctta gcccagttga cttccttctt
     7321 cgtcgtacca accatatgct ctttatgcgt gatagcttgg atagcatcgt tgagccagtt
     7381 ttggatgaaa tgggacgatt ctatgactgg acagaagaag aaaaagcaac ttaccgtgct
     7441 gatgtcgaag cagctctcgc taacaacgat ttagcagaat taaaaaatta agaaaaaata
     7501 aaagaggtgg agggcagcat tccttgtcgc ccgtcccttc tttttaatgg agacagaaag
     7561 atgatgaatg aattatttgg agaatttcta gggactttaa tcctgattct tctaggaaat
     7621 ggtgttgttg caggtgtggt tcttcctaaa accaagagca atagctcagg ttggattgtg
     7681 attactatgg gttgggggat tgcagttgcg gttgcagtct ttgtatctgg caagctcagt
     7741 ccagctcatt taaatccagc tgtgacagtt ggtgtagctt taaaaggtga cttgccttgg
     7801 gcttccgttt tgccttatat cttagcccag ttcgcagggg ccatgctggg tcagattttg
     7861 gtttggttgc aattcaaacc tcactatgag gcagaagaaa atgcaggcaa tatcctggca
     7921 accttcagta ctggaccagc catcaaggat actgtatcaa acttgattag cgaaatcctt
     7981 ggaacctttg ttttggtgtt gacaatcttt gctttgggtc tttacgattt tcaggcaggt
     8041 atcggaacct ttgcagtggg aactttgatt gtcggtatcg gtctatcact aggtgggaca
     8101 acaggttatg ccttgaaccc agctcgtgac cttggacctc gtatcatgca cagcatcttg
     8161 ccaattccaa acaagggaga cggagactgg tcttacgctt ggattcctgt tgtaggccct
     8221 gttatcggag cagccttggc agtgcttgta ttctcacttt tctagtttat actcttcgaa
     8281 aatcaaattc aaaccacgtc agcgtcgcct taccgtactc aagtacagct tgcggctagc
     8341 ttcctagttt gctctttgat tttcattgag tattagaaaa caattatgtt gatagagctt
     8401 gggcaagagc ccaatttcag caaaaaatga agtaaatctt ctcataataa aacgcatcat
     8461 atcaagcacg aaaattccac gaggtcaact acagtcagaa agctgaacaa caagccaaaa
     8521 cgcccaaaaa aggcggcaaa aagcaagcac ctgcaagcaa cgtgccgaaa tggtcaaatc
     8581 ctgattatgt caacgaatta gacccaaaaa tcgttgatat gctagtagaa tttcacaagt
     8641 cacaaggcac tttggaaact cccgaggcgc aagcagaaat cgcccaaaaa cgtgaagaaa
     8701 tcgagcaaag gagagctgag cttgaggata aaaaacaaga gcttttgaac cgcttgaaca
     8761 aatagagttt cgcaagtatt atgcttacaa attacttgag caattaacta aaatataaac
     8821 cctgccttta tatctaggca gggtttatat tttagaaatt cacgtaggtt gttacggttt
     8881 ttacataccc agtatagttt gagtttctat agtattcagt gataaacttc cattttcttt
     8941 gagcaacatg gatataagta cttgttatgt agtatggata tgggctttgt gaatccaagt
     9001 aagactgata agcttgtata ccaaaatatg ctccaccaat tattgcaccc catggacccc
     9061 ccaataaagc acctatccta ccaatcatat aactgattcc agtaccagtc atgaagttag
     9121 cgaatgtgtt agcttgttta ttcccatgta ttgtgttgac gtaattccaa acattaggat
     9181 cgtatgatct aaaagatata tttaggtcga tttcattctt ttgataagcc atataaaatg
     9241 ccccattgat atagacgccg tcagcacgtc gttcaatagt gtctacactt ccatctggat
     9301 tgacaacctc aagaacttca tcgcttaaaa tatttacttg cgtatctccg aaccgcactg
     9361 atgagccatt ctcaaactga gcctcaccag atacaacttt agagtttgcc gataagctat
     9421 catcagcaaa aacaacaagc gacggggaaa tgctagacat acagaaaaca gacataacta
     9481 gcaaacacat gcatttaaac atcttagaca taacggaaac tcttttgtat ttttgatttt
     9541 tttcaacttt tattatacaa taaaaccaaa taaaaagaaa gcggtaacaa tatgcttaat
     9601 gcgaaaattt tttatatatt tttatgtttg atcgttatcg aaactacagg cttgttgttg
     9661 ttgaaaagag gtctcgaaat gggttattta gacacagaag ctattatcct cgcagttttt
     9721 tcatttgctt tttacaacct atgttcattc gcttgggtct gctctacaat aaaaaacaat
     9781 aaaaaacaat aaaaaataaa tagacgtatt ttcaaaaaaa aaaaaatgca tatttatctt
     9841 agcaaaacga cgatttaaat cgtcgttttt ttgtagtacg acgggcatgt cgtatatctg
     9901 aggtgtaagt cctcggtggg cacctgctac cggtgaaccc aatagcgatt cccaagcctg
     9961 actatcgtga ggtagcaggg agaggaaggg atagcgaaat cgtggctcta cgaacaggaa
    10021 cgtgatagta aggcgtatat agcggataag gaggcttcaa actctaaagt ccaaaaaggt
    10081 agtcgtaacc tatatgtgta aatcacgaga gtaattgaat tcggactaag gtttgtgtga
    10141 aaaagataaa tctttctaga gtctaaagac tctgcgtcag atttcctatt ttcactgtaa
    10201 ccttttaacg tcctcatatc ttgtataaac gaggaaagat gtacgactta tcccgtgagg
    10261 tctcatgagt gctgaaagcg tagtaacaac gaatcatgag aagtcagccg aacccatagt
    10321 agtgaggaaa cttccgtaat ggaagtggag cgaaggggtg aatactcaaa cagtctgggg
    10381 agagactgtt tgaggtctgt cgctagaaag agaaaacgac agattgaagt aatcctactt
    10441 cacttgtgtc tgtaaaatga gtggtctgat agaactggac tttgacacgt actgactaga
    10501 tgaaggttca ccaatataag atgtccctca ggcaccaaaa caagaaagga atacgcacat
    10561 gtcaaaactg ctagataaga tattatcacg cgaaaatatg ctggaagcct acaatcaagt
    10621 aaaatccaat aaaggctcag ctgggattga tggaatgact atcgaagaga tggataatta
    10681 tttcagacaa aactggcgct tgactaagga actgataaaa cagagaaaat ataagcctca
    10741 accagttctt aaagttgaga tacctaaacc agacggaggc atccgtcaac taggaattcc
    10801 aacagttatg gatagaatga ttcaacaggc cattgtccaa gtcatgagcc ccatttgtga
    10861 accctatttc tcagatacga gttatggttt cagaccaaat aggtcatgcg aaaaagccat
    10921 catgaagctc ttagaatact taaatgacgg ctatgagtgg atagtggata tagacctaga
    10981 gaaatttttc gatacagttc ctcaagatag attgatgtcc ttagtacata acattatcga
    11041 agacggagat acggaatcct tgattcgtaa gtatcttcat tcaggtgtta tcattaatgg
    11101 tcaacgttat aaaacactag ttggtacacc acagggagga aatttatctc ctctcttatc
    11161 caatatcatg cttaatgaat tggacaagga attagaaaag aggggacttc gatttgtgcg
    11221 ctacgcagat gattgtgtga ttacggtcgg aagcgaggca gccgctaagc gtgtgatgta
    11281 ttcagtcagt cgttttattg agaaacggct aggtttgaaa gtaaacatga ccaagactaa
    11341 gattaccaga ccaagagagt tgaaatatct aggttttggg ttctggaaat catcagatgg
    11401 ttggaaaagc cgtccacatc aagatagtgt tcggagattt aagcttaaat tgaagaaact
    11461 aacacagagg aaatggagta tagatctaac aagacgtatt gagcaactga atttgtctat
    11521 tcgaggatgg ataaactatt tctcattggg aaatatgaaa agtatagtcg ccagcataga
    11581 tgagcgcttg cgtactcgcc tacgagtgat tatctggaag caatggaaga agaaatcgag
    11641 acgattatgg ggatttctta agttaggagt tcctaaatgg atagcagata aggtatctgg
    11701 ctggggcgac cattatcaat tagtagctca gaagtcggta cttaaacgtg ctatatcaaa
    11761 accagtcctt gaaaaacgtg gactggtttc gtgtttggat tattaccttg aacgacatgc
    11821 gttaaaagtt agttgaaccg ccgtatgccg aacggcacgt acggtggtgt gagaggggct
    11881 agagattatc ccctactcga ttaactcccc tgaaatttat tttaattatg caaatttcac
    11941 gtatttttga tgctgagacg acgatcctgg gaacttttca gatatttttt tgactatcta
    12001 aatctatcat tagaaaagct tagagcgcca aaggatttga gcgtttttct gatttttaag
    12061 actttttcca gtctcttttt cgattgaaga tgtaattatt ctactaacta actaacttct
    12121 tagtactagc caacaacgat aatcataatt cctcctaaaa ttaggaataa taaaggcaat
    12181 agtttttgtt ttttcatgta aaaaacctca cttttgtttt ctgctatttt atgctaaaat
    12241 attaaaaatc aaatttaatt ccaaagtttg taactaaagg gggagcgcta catgtctaat
    12301 tcatttgtca agttgttagt ctctcaatta tttgcaaatt tagcagatat tttctttaga
    12361 gtaacaatca ttgctaacat atacattatt tcaaaatcag taattgccac atcactagtt
    12421 cctatcttaa taggaatatc ctcttttgtt gcgagtcttt tagttccgtt ggttactaaa
    12481 aggttagcgc taaatagggt tttatcttta tctcaatttg gaaagactat attattggcg
    12541 atactggtag gaatgtttac cgtaatgcaa tccgtagcgc ctttggtgac ctatctattt
    12601 gttgttgcaa tttccatact agatggtttt gcagcacccg tttcctatgc tattgtgcca
    12661 cgctatgcga ccgatttggg taaggctaat tcagccttat caatgactgg tgaagctgtt
    12721 caattgatag gttggggatt aggtggactc ttgtttgcaa caattggtct gttacctacc
    12781 acgtttatca ttttagtctt gtatatcatt tctagctttc tgatgttatt tcttcctaac
    12841 gctgaagtgg aggtgttaga gtcagaaact aatcttgaaa ttttgctcaa aggttggaag
    12901 ttagttgcta gaaatcctag attaagactt tttgtatcag caaatttatt ggaaattttt
    12961 tcaaatacga tttgggtttc ttccattata cttgtttttg taacggagtt attaaataaa
    13021 acggaaagtt actggggata ttctaataca gcatactcta ttggtattat aattagtggc
    13081 ttaattgctt ttaggctatc tgaaaagttc cttgctgcta aatgggaaag tattcttttt
    13141 cctcttgtag ctatggcaat agtgacactg actattctat attttccaaa cgcacagatg
    13201 tttttattat tttcagcttt agttggtatg ttatcgcaac taaaagaagt tcctgaaagt
    13261 gtatttcttc aggaaacagt agaggaaaat catttagtta atgtctattc cgttcttgaa
    13321 gtgatttcta cattagcatt ttcagtattt gttttgctaa tgagctatat tactgagagt
    13381 tttggtatta gcatcagttt ttggctatca gccatttgtc tgatgataga agctatttta
    13441 atttatatca gacgagatta ttttaaatga gagagtggtt aaaaagtctt taaaaatcag
    13501 aaaagcgcat agtatcaggt gttgaaaaaa cttgatattg tgtgttttat tatgggaaga
    13561 tttacttcat tgtctcctga aatggagttt tgaagcagga tcactctatt tgaaaatata
    13621 catagaaaaa ccgcataatc cttaaaataa gctgaaatct attggaaaca tacggtaaac
    13681 aattgaaaag atactatata aagtggtaca atggtagaaa aataagctag taagaatcac
    13741 tcttatttta gcgaaaaatt acagaaatga atggtttttc ttgatgaaac agagaaaaga
    13801 attgtacctc tttcttggtc ggacagcctt gtattttctt atctttctag ggctgcttta
    13861 cttctttagc tatcttggtc agggtcaagg aagctttatc tataatgaat tttaacttga
    13921 aggagaatcc ctattgtgtc aaataaacca atagcagata tgattgaaac cattgagcat
    13981 tttgctcaga cacagcctag ctatcctgtc tataatgttt tggggcagga acacacttat
    14041 ggcgatttaa aggctgattc ggatagttta gctgcagtca ttgaccaact aggcttgcct
    14101 gagaagtctc ctgtggttgt ttttggtggc caagaatatg aaatgttggc aacctttgta
    14161 gcgctgacta agtcaggtca tgcctacatt ccaattgata gccattcggc cttggagcga
    14221 gtttcagcta ttttagaagt agcagagcca agcttgatta ttgccatttc agcctttccc
    14281 ttggagcagg tttctacacc aatgataaat ctagctcagg ttcaagaagc ctttgcccaa
    14341 gggaacaact atgaaatcac gcatccagtc aagggagatg ataattacta cattatcttt
    14401 acttctggta cgactggtaa gcctaaggga gtgcagattt cacatgataa tctcctcagc
    14461 tttacaaact ggatgattac ggataaggaa tttgcgacac cgagtcgtcc gcaaatgctg
    14521 gcacagccac cttattcttt tgacttgtct gtcatgtatt gggcaccgac cttggcactt
    14581 ggtggtacgc ttttcactct tccttcagtc atcactcagg actttaagca actctttgcg
    14641 gctatctttt cattgccaat cgctatctgg acatcaacac catcctttgc agatatggcc
    14701 atgttatctg aatacttcaa cagtgagaaa atgcctggaa tcacgcattt ctactttgat
    14761 ggtgaagaat tgacggtcaa aacagctcaa aaactgcgcg agcgtttccc aaatgcccgt
    14821 atcatcaatg cttacggccc aacagaagcg acagtagctc tgtcagcagt tgccgtgaca
    14881 gacgagatgt tagcgactct caaacgccta ccaatcggct ataccaaggc tgattctcca
    14941 acctttatca ttgacgagga aggaaataaa ctgccaaatg gcgaacaggg agaaatcatt
    15001 gtttctgggc cagctgtttc aaaaggttat atgaaaaatc ctgaaaaaac agcagaagcc
    15061 ttctttgagt ttgaaggtct gccagcctat cacacaggcg atgtgggaac catgacagat
    15121 gagggcttgc ttctctacgg cggacgcatg gacttccaga ttaagtttaa cggttaccgc
    15181 attgagttag aagatgtctc tcaaaacctc aacaagtctc gctttatcga atctgctgtc
    15241 gcagtaccgc gctataacaa ggaccacaag gtacaaaatc tattggctta tgtcatctta
    15301 aaagacggtg ttcgtgagca gtttgagcga gatatcgata ttaccaaggc catcaaggaa
    15361 gacctgacag acatcatgat gtcctatatg atgccatcta aattccttta ccgagacagt
    15421 ttgccactaa ctccaaatgg aaagattgac atcaaaggat tgattaacga ggtgaataag
    15481 agatgatgga gttttttcaa cagcttcctc atttagagcc atatggcaat cctcagtatt
    15541 ttgtttatgt gattgctgca accttgccca tctttatagg tctctttttc aagaaacgct
    15601 ttgcctggta tgaagtgttg gtaagtctct tctttattgt caccatgttg gtgggtggaa
    15661 agaccaatca actagctgcc ttgggtattt acctttgctg ggaaatattg ctcctgcttt
    15721 tctacaagca ttatcgaaaa agcaaggatg gcaagtgggt cttctactta gttagttttc
    15781 tgtccctact tccgattatc tttgtcaagg tgcaaccagc tatcaatgga acgcagtctt
    15841 tgcttgggtt cttgggaatt tcttacctga cctttcgttc ggttgggatt atcatcgagc
    15901 tgagagatgg agtgattaag gattttaccc tctgggaatt cctccgtttc cttctcttca
    15961 tgccaacttt ctcgagtggt ccaatcgatc gctttaagcg atttaatgaa aattatcagg
    16021 ccattcctga gcgagatgag ttgatggata tgctggatga atctgtccgc tatatcatgc
    16081 ggggcttttt gtataagttt atcctagctc atgttttagg agagacctta ctccctcctc
    16141 tgaagaattt agccttgcag tcaggtggct tctttaatct ctatgccttg gcagttatgt
    16201 atacttttgg tctggagctc ttctttgact ttgcaggtta ttctatgttt gctttggcca
    16261 tctcaaactt gatgggaatc cgtagcccta tcaactttaa caagcccttt ttatcaaggg
    16321 atttaaagga gttttggaat cgctggcata tgagtctgtc cttctggttc cgtgactttg
    16381 tctttatgcg aatggtgatg gtgttaacca gaaagaaagt ctttaaaaat cgtaatgtaa
    16441 cctcaagcat ggcctacatt gtaaatatgc tgattatggg attttggcat ggcgtgacct
    16501 ggtactatat cgcctatgga ctctttcatg gactaggctt ggtcatcaat gatgcctggg
    16561 ttcgcaagaa aaaaacgctc aataaggaac ggaaaaaagc ggggaaggct gccctacctg
    16621 agaatcgctg gattcagttt cttggcatgg ttgtcacttt ccatgttgtc atgttgtcat
    16681 tcttaatctt ttctggattc ttgaataatc tatggtttaa aaaataaaag gaaataaaat
    16741 atggatatca aatcagaagt tattgaaatt attgatgagt tgtttatgga agatgtttct
    16801 gacatgatgg atgaagatct ttttgatgca ggtgtcttgg atagtatggg aacggttgag
    16861 ttgattgtgg agattgagaa ccgttttgac attcgtgtcc ctgtaacaga gtttggtcgt
    16921 gacgactgga atacagctaa taaaatcata gctggtattg tggagctaca aaatgcttaa
    16981 acgcttatgg atgatcttcg gaccggtctt gatcgctggt ttgttggttt ttctgctcat
    17041 tttcttttat cctactgaga tgcatcataa tctaggagct gaaaagcgtt cagcagtggc
    17101 tactactatc gatagtttta aggagcgaag tcaaaaagtc agagcactat ctgatccaaa
    17161 tgtgcgtttt gttcccttct ttggctctag tgaatggctt cgttttgacg gtgctcatcc
    17221 tgcggtatta gctgagaaat acaatcgttc ctaccgtcct tatcttttag gacagggggg
    17281 agctgcatcg cttaaccaat attttggaat gcaacagatg ttaccacagc tggagaataa
    17341 acaagttgtg tatgttatct cacctcagtg gttcagtaaa aatggctatg atccagcagc
    17401 cttccagcag tattttaatg gagaccagtt gactagtttt ctgaaacatc aatctgggga
    17461 tcaggctagt caatatgcag cgactcgctt actgcaacag ttcccaaacg tagctatgaa
    17521 ggacctggtt cagaagttgg caagtaaaga agaattgtcg acagcagaca atgaaatgat
    17581 tgaattattg gctcgtttta atgaacgcca agcctccttt tttggtcagt tttcggttag
    17641 aggctatgtt aactacgata agcatgtagc taagtattta aaaatcttgc cagaccagtt
    17701 ttcttatcaa gcaatagaag atgttgtcaa agcagatgct gaaaaaaata cttccaataa
    17761 tgagatggga atggaaaatt atttctataa tgagcagatc aagaaggatt tgaagaaatt
    17821 aaaggattct cagaaaagct ttacctatct caagtcgcca gagtataatg acttgcagtt
    17881 ggttttaaca cagttttcta aatctaaggt aaacccgatt tttatcattc cacctgttaa
    17941 taaaaaatgg atggactatg ctggtctacg agaggatatg taccaacaaa cggtgcagaa
    18001 gattcgctac cagttagaaa gtcaaggttt taccaatata gcagattttt ctaaggacgg
    18061 cggggagcct ttctttatga aggacaccat tcaccttggt tggttgggtt ggttggcttt
    18121 tgacaaggca gttgatcctt tcctatccaa tcccacacca gctccgactt accatctgaa
    18181 tgagcgcttt ttcagcaaag attgggcgac ttatgatgga gatgtcaaag aatttcaata
    18241 gataatataa tatagaagag ttcaagaatg aaactagttt tcacgttttt tcttgactct
    18301 ttttttgctt gtgatataat taactggtaa acaaaatgtc aaagaatagt atttttctct
    18361 taaaaaagag aagtctaaaa ggaaaggagt cagatatgag acagctagca aaggatatca
    18421 atgctttttt gaatgaggtg attttgcagg cggaaaatca gcatgaaatc ctaataggtc
    18481 attgcactag cgaggtggcc ctgaccaata ctcaggagca tatccttatg ctcttgtcag
    18541 aggaatcttt aacaaattca gaattggccc gtcgtctcaa tgtcagtcag gcggcagtta
    18601 ccaaggccat taagtctttg gtcaaggaag ggatgttgga aacatctaaa gattctaaag
    18661 atgcgcgtgt gattttttat cagttgactg acttggctcg tccaatcgct gaggagcacc
    18721 accatcacca tgagcataca cttttaacct atgaacaagt ggcgactcag tttactccaa
    18781 atgaacaaaa agtgattcag cggtttttga ctgctttagt aggagaaatc aaataatgag
    18841 atatattacg gtagaggatt tgtccttcta ttatgataag gagcctgttc ttgaacatat
    18901 caattatagt gttgatagtg gggaatttgt taccttgact ggggaaaatg gagcggctaa
    18961 gacgacgctc atcaaggcta gtcttggaat tctgcaacca cgcattggaa aggtggctat
    19021 ttcaaagaca aatacgcaag gtaagaaatt gagaatagcc tatcttcctc aacaaattgc
    19081 cagttttaat gctggttttc caagtacggt ctatgaattt gtcaagtcgg gtcgctatcc
    19141 gagaaaaggc tggttccgtc gtttgaatgc tcatgatgag gagcatatca aggccagtct
    19201 ggactcagtt ggcatgtggg aacatcgaga caaacgcttg gggtctctat ctgggggaca
    19261 aaagcagcga gcggtgattg cgcgtatgtt tgcttctgac cctgatgtgt ttatcctaga
    19321 cgagccgaca acggggatgg atgcaggaag taaaaatgaa ttttacgaac tcatgcacca
    19381 caacgcccat catcatggca aggctgtttt gatgattacc catgaccctg aagaagttaa
    19441 ggattatgcg gatcgcaata ttcatctagt ccgtaaccaa gactcgccat ggcgttgttt
    19501 caatgttcat gagaatggcc aggaggtggg ccatgcttag tttattatct tacgacttta
    19561 tacaacgcgc ctttttggcg gttattgcta tgagtctttt ctcaccggta ttgggaacct
    19621 tcctcatctt gcgtcgtcag agtttgatga gtgataccct tagccacgtc tcactttcag
    19681 gtgtagcctt tggtctggtt ttggggattt ctccaactgt ttctactatt gccattgtct
    19741 tgattgcggc ggtctttctg gagtatctcc gtacggttta caagagcttt atggaaatcg
    19801 ggacagctat cctcatgtca acaggtctgg ctgtttctct gattgtcatg agcaagggta
    19861 aaagctcgag ttcaatgagt ttggaccaat atctctttgg ttcgatcgtg actatcagtg
    19921 aagaacaggt catttccctc tttgtcattg cggcggttgt tttgattttg acctttctct
    19981 ttcttcgtcc tatgtatatc ttaacttttg acgaagatac ggcctttgtg gatggcttgc
    20041 cagttcgtac catgtccatt ctttttaaca tggtgacagg ggtggctatt gcccttatga
    20101 ttcctgcagc aggagctctt ctggtatcga ccattatggt cttgccagct agtattgccc
    20161 tgcgtctggg gaaaaacttt aaatcggtta tgctgcttgc cagtgcgatt ggctttttgg
    20221 gaatggtagc aggactttac atttcctact atgcagaaac acctgcaagt gcaagtatta
    20281 ccattatttt tgtaactgtc tttatactaa tcagtttagt aagacgtttt atcaaatagg
    20341 agacgaacgt gaaaaaaatt agcttattac tagccagtct atgtgccttg tttttagtgg
    20401 cttgttccaa tcaaaaacag gcagatggta aactcaatat cgtgacaacc ttttaccctg
    20461 tctatgaatt taccaagcaa gtcgcaggag atacggctaa tgtagaactc ctaatcggtg
    20521 ctgggacaga acctcatgaa tacgaaccat ctgccaaggc agttgccaaa atccaagatg
    20581 cagatacctt cgtttatgaa aatgaaaaca tggaaacatg ggtacctaaa ttgctagata
    20641 ccttggataa gaaaaaagtg aaaaccatca aggcgacagg cgatatgttg ctcttgccag
    20701 gtggcgagga agaagaggga gaccatgacc atggagaaga aggtcatcac catgagtttg
    20761 acccccatgt ttggttatca ccagttcgtg ccattaaact agtagagcac atccgcgaca
    20821 gcttgtcagc agattatcct gataaaaaag agacctttga gaagaatgca gctgcctata
    20881 tcgaaaaatt gcaagccttg gataaggctt acgcagaagg cttgtctcaa gcaaaacaaa
    20941 agagctttgt gactcaacac gcagccttta actatcttgc cttggactat ggactcaaac
    21001 aagtcgcaat ctcaggactt tctccagatg cagagccatc agctgctcgc ttggcagaat
    21061 tgacagagta tgtcaagaaa aataaaatcg cctatatcta ttttgaagaa aatgcctcac
    21121 aagcccttgc taacacactt tcaaaagaag caggtgtcaa aactgatgtc ctcaatcctt
    21181 tagaaagtct gacagaagag gacaccaagg ctggagaaaa ctacatttcc gtgatggaga
    21241 aaaacctcaa ggctttgaaa caaacaacag accaagaagg cccagcaatc gaacctgaaa
    21301 aggcagagga taccaagaca gtccaaaatg gttacttcga ggatgcagct gtcaaggacc
    21361 gcaccttgag tgactatgca ggtaactggc aatcagttta tcctttcctt gaagacggca
    21421 cgtttgacca agtctttgac tacaaggcta agttgactgg taagatgacc caggctgagt
    21481 acaaggctta ctatacaaaa ggctatcaga cagatgtgac taagattaac attactgata
    21541 atactatgga atttgttcaa ggtggacaaa gcaagaaata cacttacaag tatgtcggta
    21601 agaaaatttt gacttacaag aaaggcaatc gtggcgtgcg tttcctcttt gaagccacag
    21661 atgctgacgc tggacaattc aaatatgttc agtttagtga ccacaatgtt gccccagtta
    21721 aggcagaaca tttccatatc ttttttggag gtacaagcca agaagctcta tttgaagaaa
    21781 tggataattg gccaacctac tacccagata acctatctgg ccaagaaatc gcccaagaaa
    21841 tgttggcgca ttgatgagaa atcgactagt tcataagagc tagtcggttt tttgatacta
    21901 gatggctaac ttcattatag acctttcaga actaagggaa cctgaaaaaa taaataaaac
    21961 tcttgaaata tctggactta tatgctagaa tgtagttagt gtataaggtt cattagaaca
    22021 ccaaagcccc taactagtgc catagttaag ggcttttttg acgtatctta gcgatttaat
    22081 gggtgtttat aggctagtca gtcggtctac ttcttaccat ctagccattt gcagacgaaa
    22141 tacaagataa ttccagctat aacatctgct ataatagtaa gagcaagctc tggtataagg
    22201 ctcattagtt tcacctcctc tcacgaaccc ataggaacgt aatcggtaac cgatgacaaa
    22261 aatagtatac cacactaaat ttagatcatc aacctcactt aatacttgaa ctattgtaga
    22321 ttatatgcta aaatgtagtt aattgataag gttcattaga acaccaaagc ccctaactat
    22381 ggccgtagtt aagggctttt ttgacgtatc ttagcgattt aacgggtgtt tataggctag
    22441 tcactcggtc tactccttac tatctagcca tctgcagacg aaatacaaga taattccagc
    22501 tataacatcc gctataatag taagagcgag ctctatgata aggctcatta gtttcacctc
    22561 ctctcacgaa cccataggaa cgtaatcggt aaccgatgac aaaaatagta taccacaata
    22621 catttagatc atcaaggtca cttaattctt gaaatatagg gtctatgcga caaagtcttt
    22681 aaaatcagaa aaacgcataa tatcaggtgt gcaaaaactt gatactatgc gttttattgt
    22741 gggaaggttt actccatttt ctcctgaaat tgagtttttg tccagcctct gtttttagaa
    22801 ttgctaagaa aataatgtca tgtggtgaat atttgtaaat cagtcagcag acagaacgaa
    22861 tactcttcga aaatctcttc acatcatgtc agcttcgtct tgccgtgtcc atgggggact
    22921 tgacttcatc agttttcaaa tctgtacttt gagcaagctg agactagctt cctatttgat
    22981 tttcattgaa tatcagaaac ccattctcca tcaaataatt cgactgcatc taataatttt
    23041 tggtctggca aggtgtcaga aataaaggtt gtgtatttgg ataggggatt aattttaaaa
    23101 aaatccagtc ttgtaaaatt tagaactatc aatcagtaag atggtttcat gggctttgtc
    23161 aataatattc ttttttgaaa tagcttggct gagagaagct tcataaacat attggtcatc
    23221 aatacctctt gctgaacaaa atgctaaatc gatattaaaa tgatctaata aagaattttc
    23281 cttatcatag ttgaccacgg aacaggattg atgtttgacc tcgccagatg tgataaagat
    23341 tttggagcta tctttaacag tttcagatag ggtttgtgca gtatgtaaac catttgtaaa
    23401 aataatcaaa ttatcaagtt cagaaagata gggacagagt tcgtagacag tcgtactgga
    23461 atcaagataa atacacatgc ctgaccgaat aaagtcttta gcgagactag cgattagtct
    23521 tttttgccta gtactttctc cttcccgtat ttgatgagaa agttcaattg tgttcataga
    23581 ggacagggtc acgtatccgt gctttctttt gataagacct tgattttcta agaaaattaa
    23641 atcacgacgt aaggtacttg tgctggagaa agtgatttct gccagctctt ttacggcaat
    23701 tctttttttc tttttaataa tttcaatcaa ttcaagtaca cgttcatctt ttatcataag
    23761 ctcctcctaa tttatcattt caactatatt atagcacaaa ttggaggaat ttgaattatt
    23821 tttatgaata ttgggttaat atttgaacat tattcaagta agcgttcaca tattgaaaaa
    23881 ataaaacgtg gggattataa taaagttaat caaggacgaa gagagaagaa aaatggaagc
    23941 ggttttagca atagatttag gtgcgacttc tggaagagca atcgttggtt acctttctga
    24001 aaataaacta gtaatggaag aaataaatcg cttttctaat ctacctatta gagtaaaagg
    24061 gcatttatct tgggatattg actttctact agctaaaatt cttgaaagta tccgcttggc
    24121 taatactagt tacaagattt tatctatcgg tattgacaca tggggagttg attttggact
    24181 gattgataat gaaggtaagc tgttattaca acctgttcat tatcgtgatg aaagaacaaa
    24241 gggagtgtta aaggaaatat ctgaaatgac tgaattagaa aaactgtatt cagagacagg
    24301 aaatcagatt atggagataa ataccttgtt tcaactcttt aaggcacgtc aagaatctcc
    24361 tgactctttc tataagacca ataagattct tttaatgcca gatttgttta attatctctt
    24421 gacaggtaag tttgctacag aaaaaagcat tgcttcaaca actcaattat ttgatcctag
    24481 gagtcaaaac tggaatcaga atatcttaaa actatttgaa ttggattcat ctttacttcc
    24541 tgagattgtt tcagagggaa atgttcttgg aaggataaaa aaggagtatg gtttaggcga
    24601 tattcctgtt gtgaatgttt gtagtcatga tacagcaagc gcgattgtct cagtacctaa
    24661 gacagaaggt agtttattta tttcatcagg tacttggtct ttggttggag tggaacttac
    24721 ttcaccgctt cttactaccg aatccttcag ttatggattt acaaatgaag tcggtaaaga
    24781 tggagtgatt acatttctga agaattgtac agggttgtgg atcatagagg aactaagacg
    24841 ttcatttgaa cgaagaggga aagcctattc ttttgatgat attaggacaa tggtggagaa
    24901 agaaaaagaa aatcttcctc tgattgatac tgaatcaact gaatttgcaa cagaatctga
    24961 tatgcacaag actttgacag aatatctagc ttatcatcat gaaactagag agtggacaga
    25021 tggacaacta tttaagattg tttatgaaag cctagctgaa acgtatagga aagcgataga
    25081 gttactagaa gaactaactc ataaggttta taagaggata tatgtgattg gaggaggtgc
    25141 tagagccagt tactttaacc aaatgattgc tgatagaact ggtaaagagg ttcttacagg
    25201 tttgactgag ggtacagctg tggggaatat tgttgtgcag ctattgagtc aaggtaaaat
    25261 aaacgaggat acagagttaa aggatattat gacaaatatt gctgagacac aatattatta
    25321 tcctcagcta tcataaacaa aaataaaaaa acggaggttt tgtcatgaac aaaaaaagtc
    25381 ttttgaaatg cgctgttatc gggttagtag ctacctttgg tttagcagct tgtggaacat
    25441 ctaaggatgc aagcggtgga agttcttctg gtaaagaagt attagaattt tatcatgggt
    25501 atcatcatag tgaagatgaa tggcctgtag cgaagactat gcgagattta tatgataaat
    25561 ttgcagaaga acataaagat agtggtgtag aatttaaacc aactcctgta aatggtgatt
    25621 tgaaggatat aatgaataac aaggttgcta gtggtgaatt tcctgatgtg attgacctag
    25681 caggtaatgc agtatcatta gttgcgattg aacaaaaact tgttttagat ttgaaaccat
    25741 atatcgattc aaataagctt gaaaaaaatg ttggtttgaa ctataagcaa aaccaaaaag
    25801 atggaaaaat ttatacagtt cacgaacagt tatttacaat gggtttgtgg tacaacaagg
    25861 acatatttgc aaaagcgggt gctaagacac ctgatcagtg gaatacttgg gatgatttca
    25921 ctcaggcaat ggcaagcatt agaaaacaag atggagtgta tgcatttggt gctggagaac
    25981 catctattcg cttgtttaat acagtattag gaaccacaga aaatggacgt aaattattag
    26041 ataaaccatt aacaaaagaa ggaattgaat ctaaagaatt tgcagatgct ttgaaaatgg
    26101 ttatgaaaga aattcaagct aatggttcta agaatgctgg tggcgatgcc aatgcttatt
    26161 ccaaagattt ccaagaaggt aaatctgcag tattctttaa tggtgtgtgg gcttctggtg
    26221 agatgtctaa gaacccaagt cttgcacctg gaatctatcc tgcaggtgta gcaattagtt
    26281 cttctggagg tggtatcact atctcaagta agatgtctga agctaaacaa aaactagctc
    26341 ttgagttttt gaaatatatg actagcgatg atgtacaaaa agtaattttt gaaaaagtag
    26401 gagcaaatcc ttctaatgaa aatgtaaatg taaaagaact ttcagaaaag agttcagaag
    26461 ctactactaa aattttagga caagcaatca ctcaagttaa gaatgcaaaa gcagttgttc
    26521 caactgtaag tgatgtttgg ggtggcgatg tacagacagc tattatcaat gcattgacag
    26581 aaagtgctgc tgaaaatgta gatgttgatc aaaaagtaaa atctactcaa gatgtgttga
    26641 aatcattgat tggttaattg ttttagggag tgaaaacgaa gctcagttgg cactgccaac
    26701 tgagcttgat tttacttata tagttgaaaa aaggagtttg tttatggcac aaaaaattat
    26761 gagcctacaa aataggaaga atcaaaaaag acgatttatc tttttatttc ttttgccaac
    26821 gttgatttgt ttctttctat tttattttta ttctgtagta acaatctttt taacttcatt
    26881 tgctaaatgg gattatacaa atttaaacac ccctgagttt cttggatttg ataaattatt
    26941 tgaaaattat aggtatgttt ttaaagaata cccatttttt acagaagctc taattaattc
    27001 tgttcgttgg gctgtaattg gtgttattat tcaagttcct ttagctgtat ctgttgcaat
    27061 tacattatct aagaaattaa aaggctggaa gatatctagg aatctttata ttgtaccaag
    27121 tatcatttct agtgctgcta tgggcttgat ttttcttcaa atctataatc caaactatgg
    27181 tgttgttaac caaattattc atctatttaa tccatcgttt aaagattcag tactgttgac
    27241 tccaggatta aatatagtag ctatgactgg cgcttatatc ttctttgcag gagcatcaac
    27301 cattatgatt cttgggcaaa tttttgctat tccagaagaa gttcaagaag ctgctatttt
    27361 agacaatatt actggttgga ggaaagagtg gtatattacg attccgatga ttaaggggac
    27421 aattaaaact gtttcaatta tggcagcaac ttcagggttt ttgctctata acgaagtatt
    27481 ctttttgaca aatggtgctg caggaacaaa aagtatcagt tttgttattc gagaattagc
    27541 agtggctagc tcacgaactc agtatgctcg tgcaaataca attggagtta tacaaatttt
    27601 aggtggaatg ttgattatct tttgtattaa tattttattc agagaaagaa aaagactgaa
    27661 aggtgggaaa tgattatgaa tacacatata aatggtatta gtaaaaaagg caaagttctt
    27721 atatatggtt atatgctcct taccatttta atttctattt tccctattgc gtggattttt
    27781 ttatcatcat taaaagcaga tcctatgaaa aatccaggta ttagtttacc gactgacttt
    27841 actcttgaag gctatataaa tgtttttaca aaacttcatg ttttcactta cttttggaat
    27901 agctttaaag tagtgtctat atcagttatt attagcattg ttatgatctc catgtcttca
    27961 tatgttattg ctaggatgga atttagaggg aagaagttgg tgacttctat gctgtattct
    28021 actctattta ttccagcaac agctatgact tttccagttt atagattagt aaatgagttg
    28081 gggatttata ataccccagt tgctctaatt ctggtctact cttgtagtgg aattgctatg
    28141 agtttcttta ttataaagaa ctattttgaa attattccaa aagaattgga ggaggcagca
    28201 gagattgatg gtgcgacata tgctcaaact ttttggaaag tgatgttacc aattgctaga
    28261 ccaggaattt taacagcagc agtacttgcc tttattaata actggaatga atattattgg
    28321 gcatctatgt tggtgattga taaaaatgaa ttaacagtac cagcattact aggtcaattt
    28381 actacaagtt ttaatactaa ttataatggt ctattttcag ctattgttgt aatcgtatta
    28441 ccaccaatca ttctattcgc atttacaagt aaatacttca ttgaagcttt aggaggagga
    28501 gcagtaaaag gatgaaacat acacttgaaa ctatcaatag tagaactcag tggtttagag
    28561 aagcaagatt tgggatgttc attcattggg ggttatattc tattccagga aaaggggaat
    28621 ggattcgtag tcatcagaaa ttatctattg aagattatga accatatttt cgagcttttg
    28681 atcctaagga atataaccct agagaatggg ctaaacaagc aaaagctgca gggatgaagt
    28741 atatggtttt aacggctaaa catcatgatg ggttttgttt gtttgattca aaatttacag
    28801 attataaagc aacaaataca cctgcaggta gagatttagt taaagaattt gtagatgctg
    28861 ttcgagctga aggtttaaaa gtaggcttat attttagttt gattgactgg caccatcctg
    28921 atttccctaa atatgctgat ctaaatcatc caatgagagg aaatgaagcc tatcgagatg
    28981 agaaaattaa ctttgacagt tatttggagt atttacacaa tcaagttaaa gaaattgtaa
    29041 ctggttatgg tcagattgac atattatggt ttgattattc ttatgaagac atggtgggtg
    29101 aaaaatgggg agcttcaaaa ttaatagaca tggttcgtca ttatcagcca aacgttatcg
    29161 tagataatag attagaaaca tcaggtgaag gattcggaag tatcgttaca gatgaaatta
    29221 cctcttacgc tggagatttt gttagtccag agcaaattgt tcctcacgaa ggtattcgaa
    29281 actttaaagg tgaacctgtt ccttgggaac tttgtctaac tatgaataac aattgggctt
    29341 ataatcctac agattatcta tataagtcta gtcaaacttt gataagaaag ttagtggaat
    29401 gtgttagtaa aaacggaaat atgattctta atgtaggccc agatgctttg ggaagaatta
    29461 atgattcaag taagaaaata ttagataatt ttcatcgatg gatgtctcga aatggtgagg
    29521 caatttatgg atgtagtgga gatgaaaatt taccaaaacc agattgggga tactatactc
    29581 gtgatgaaaa tacggtttat gctcatgtat ttgaacaacc tataggtcct ttagctcttc
    29641 ttggtattag taaagaaaac gtaaaaagaa tgagctttct tcatgatgga agtgaggtga
    29701 aaatttcaga aagctggacg accaatgcct acaaaggaat ttgttttgca cagtttggag
    29761 aagttccaca ttttacctat ccattaccag acttgattga tagcgtaatc aaaattgagt
    29821 tgagagagta gtttatatga aaattgaaaa taaaaatgta agacgtaatt tcttttgggg
    29881 agatggtcga ttttatacta ctgatatcgt aaacaaacgg gcaggagtaa tgataaaaaa
    29941 tgtttcgaaa gaagaattta ccattacatt ggagaatggt ataagacttt cttcaaatca
    30001 tttttcagca atcgttaggg aagagggaga tacgcgaatt caggtttctt ttgtttgtcc
    30061 ttccattcgt ttacgtttaa tctttgaatc gagggatgat gttctttcga agcaattagt
    30121 tttagaatca tctactgagg ttattaaatc tgtagaggta gagagttttg agtttgaaac
    30181 agaagacaat attttctatc cgaaaagaca agattgtatt aaggaaatgg cgaatttttc
    30241 cggttattat gtagaattgg gacaacctgt ttatgcgaat tctttattct taggaatgga
    30301 atttccaatg tctgaaaaca aggtagatgg tagacactat gtatcaagat attacttggg
    30361 aactgttgta aatcaagaaa agagtttgtg gtcttgtatt attgggggag catgttctta
    30421 taaaaaagaa gagattcaag aggcattttt tgaatatgtt gaaggaatag ctcaacctag
    30481 ttatttccgt aaacagtata attcctggta tgaccatatg accgatatta cagaggaagg
    30541 tattttaaaa agtttttctg agattcgaga tggatttgaa aatcatggag ttcatttaga
    30601 tgcttatgtt gttgatgatg gttggacaaa ctatcaatca gtttgggaat tcaatcataa
    30661 attcccaaat ggtttgagaa atattaaaca tcttgtaaat ggatttggtt caagcctagg
    30721 attgtggatt ggtccccgag gtggttataa tgggacagaa atcattatga gtgattggtt
    30781 agaagcacat ccagagttaa atattggatc taaaaatttg atttcaaatg atgtaaacgt
    30841 ggctgatttt aactatctca atcaaatgaa gaaaaagatg ttggaatatc aaaaagaatt
    30901 cgatatcagc tattggaaaa ttgatggttg gttacttcaa cctgacaaac ctgataagag
    30961 tggaccgcac ggtatgtata ccatgacagc ggtttatgag ttcttaattc aactgttgat
    31021 agatctaaga aaggagagag gaggaaaaga ttgttggtta aacttgactt cttatgtaaa
    31081 tcctagtcca tggtttttac agtgggtcaa tagtttatgg attcaaatat ctcaagatgt
    31141 aggctttaca gagaatgcag gtaatgatat caatcgtatg attacttacc gagatagtca
    31201 gtatcaagaa tttttggaaa aacgtgagat acagttacct atgtggtcgc tttataatca
    31261 tgaaccaatc tatgctgtca gtgcaaatac ctggtacatg gatcatcaaa tgtttgcatc
    31321 aataccagat tttgaagctt atctattatt tatttcaaca agagggaatg ctttttggga
    31381 gtttcactat tcttttgata tgtttgatga agaacgctgg aaagccaatg ctcgtgccgt
    31441 caaatggata gaggagaatt atcaaacact aaaatatagt aaaaaaatag gaggaagtcc
    31501 tgaaaaattt gaaatttatg gttataagtg tcacaatcag aagacttcta ctgaaattct
    31561 ctctctgaga aatcctgctc agattaaaca aaaaataaaa atagagaatc tttcgataga
    31621 gaattttacc agagtaattg gagattttac tattcaagaa gatgagatag aattggcacc
    31681 gtactctatc gtgatactga agaagtaaag aaaaaattgt gaggtagaga tgacgattta
    31741 tattaataag gacgagaccg tttttcattt ggcaatgaaa gatagtagtt atatttttag
    31801 aattttagaa aatggggaac ttcaacatct acattttggg aaaaggattc atgtcaagga
    31861 aaattataac caattgatgg cctatgaaaa aagaggattt gaagtatctt tttctgaaga
    31921 atttgaggat attcaacagt ctatgataca aaatgaatat tcttcatatg ggaaaggaga
    31981 ttttcggcat ccagcctttc aagttcaagg aatgaatggt agtaggataa cgacactaaa
    32041 atatcaaggt tttgaacttg aaaaagggaa aaatcgtctt aactctctac cttcaacatt
    32101 tgatgatatt ggtcagtgtg cggaaacatt aacgattatt ttaacagatt ccatattaga
    32161 tttaactgtt agactaaatt acacaatttt tccggaatac aatgtcttag ttagaaatac
    32221 ggaattttta aataatagca ataataagtt gactcttttg aaagcaatga gcttacagct
    32281 agatctacct gatagtcaat atgactttat tcaattttct ggagcatggc tgagggaacg
    32341 tcagttatat agaacttcgc ttagaccagg tattcaagca atagatagct tgagatactc
    32401 atcaagtcct cagcaaaatc ctttctttat gctatcaagg agggaaacta cagagcatag
    32461 tggtgaggtt tatggtttta actttatcta ttctggaaat tttcaaaata tgattgaagt
    32521 tgaccatttt gacaccgcta gagtaacggt aggaataaat ccagtagaat ttcgtttttt
    32581 attaaatcct gccgaaagtt ttgtgacacc agaagcaatt gtgatctatt ctgatcaagg
    32641 gatgaatcag atgagccaac aactatcaga tttttatcga catcatttag ttaatcctaa
    32701 tttttctcaa gctagtcgtc ctataatact caatagttgg gaaacatttt attttgactt
    32761 gagtacagaa aaaattttag atttagcaaa ggctgctaaa gatttaggga tagaattatt
    32821 tgtactggat gatggttggt ttggtcatag gaaagatgac aaaagttctc tgggtgattg
    32881 ggtaacagat agaagtcgcc ttcctgaagg tattggattt cttgcagatg aaattcacaa
    32941 aataggttta caatttggtt tgtggtttga gcctgaaatg atttctattg atagtgattt
    33001 gtacaagaat catgccgatt ggactatcca tttgttagac agagagaagt cagtaggaag
    33061 aaatcaatat gtgttggatt tgacgagaca ggaagttgtt gattatcttt ttgattctat
    33121 ttctaaaatc ataatcaaaa caaatctgga ttatatcaaa tgggatatga atcgtcatat
    33181 aacagatatt tatagtattg aacttgattc tgaacagcag atggaatttg gtcatcgata
    33241 tatcttaggt ctttatcagt tattagatcg tttaataact aagttccctt cagttctatt
    33301 tgaatcttgt tcttcaggtg gtggacgttt tgatttagga cttatgtatt atgcaccgca
    33361 agcgtggacg agtgatgata cggacccgat agaaagattg aaaattcagc atggaacttc
    33421 ttatggatat tctccatcaa tgatgacagc ccatgtttct atttctccaa atgaacaaag
    33481 tggaagacaa acgagtttgg acactaggac aaatgtagct tattttagtt ctttcggtta
    33541 tgaattagat gttacgagat tgtcggtaga agaaaaagaa caagtgagag aacaaattca
    33601 gttttataaa aaatatcgtt cattgcttca atatggggat ttctatagga taaacagtcc
    33661 ttttagttgt gattctgcta gttggcaagt tgtttcaaaa gataaatgcc aatcgatttt
    33721 attgtatgct caattgaata gtaagttgaa tccaggttat acaagagttt attttagtgg
    33781 tttagataaa gataaatgct attccgtctc tggatttgat gagttctttt atggagatga
    33841 attaatgaat gctggaataa aagtaagttt aagtaattta gcactttgtg ttccagaata
    33901 tcttacaaaa ttatttgtta ttgaagaagt tgtatgtaaa tattgaggaa ataaaaatgg
    33961 aaagtaaaaa aatagcaaaa cagattttaa tagctacggc tgttttaaca agttttttag
    34021 gaagtaattt ggtttatgca gatgtagttc aaagtaattc taataacaga gctagtactg
    34081 aaactgctag agtaacaggg aataacttag aaaaacttat tattaaagat aaagaaattg
    34141 ataaagagat gacatatctt tcagatatgg attggtcttc tgcaactcat ggtgatatag
    34201 ataaaacaaa aacagtacaa aaagatgctc catttacaac aggaaataaa ggagagcata
    34261 ctaagatttc attgctcact tctgatgata aagttaaata ttttgataaa ggaataggaa
    34321 cagtcgcaga ttctccatca gtaatcagct atgatatcag cggtcaaggg tttgaaaaat
    34381 ttgaaactta tataggaatt gatcaaagtg ctaatagttc tagatcagac catgcagtag
    34441 tggatagaat agaaatagaa attgatggaa aggttgtcta ttctagtagt gtaactaatc
    34501 cagaaggatt cagatataat acccaggcac aatttattag tgtgacaatt ccacaaaacg
    34561 ctaaaaaaat atccttaaaa tcattcgcag gagaacatac atggggtgat gaggttgtat
    34621 ttgctgatgc taaacttatt aaaactgtta gtactcaaac tataactcca gatcttctta
    34681 ataaaggaat taatggagga gtatatcttt ctgatttaga atgggttgat gctactcatg
    34741 gtgatgacga taaatcaaaa acagttcaga aagataaacc gtttacacct ggtaataacg
    34801 ggtctaataa taaaataaaa ttactaattg acggtaagga agtcgaattt aataagggat
    34861 tgggaactgt agcaagtaac ccgtctagta taaaatatga tgtttcgggt gctaatgtta
    34921 caagatttat ttcctatgtc ggaattgata ggagtgcaaa tcatttaaat tcagattacg
    34981 cagatattca aaaatttgaa gttgttgcgg atggtaaagt catttactca tcagattcaa
    35041 aatatccaaa aggaattaag tatgatacat cggcatttct ggttgatgtt gaaattccca
    35101 aagatacaca gacaatagaa cttaaatcat attcagggaa acatacatgg gctgacgaat
    35161 tggttttagg tggagccttg tttatggcaa atggtaaatt taagaatcct aatgattggt
    35221 cagaagttga taaacgtcgt gaaattaata atgaacatcc gttacttatg atgcctttat
    35281 atgctaacgg agaagagttt aaccaaggga aatatacttt ttggggagga gatacattaa
    35341 caggtaagtg ggagaatata ccagatgact taaaaccata tactgttata cagttacatc
    35401 cagatgatct tcctaaaaga gatggagctg ctagagattt ttatgagcat atgttagaag
    35461 aagcagcgaa atatgtaaat cctaagactg gaaaaaatga acctattcca gttattctaa
    35521 cggtttacac tgctggtaat atgccttatt atacttcggc acattggtta agtaccagct
    35581 ggattgataa aatgtatcaa aaatatccaa atttgcatgg tattttcagt actgagaatt
    35641 attggatttg ggcaaatgat attgaaaata aggcggcaga ttacttaaaa gtatcagcta
    35701 aaaatggagg atattttata tgggctgaac aaaataatgg ttctgcaata gaaaaagcat
    35761 ttggaaaaaa cggtaagata gcatttcaga aatctgttga taagtactgg aagaacctta
    35821 ttttcatgtt caaaaataca cctgctgctg agggaaatga ttcaactaca gaaagttata
    35881 tgaagggact ttggctttca aatcatactt atcaatgggg tggtttgatg gatacttgga
    35941 agtggtatga gacaggtaaa tggaaactgt ttgcaagtgg taatatcgga aaaagtcaag
    36001 gagatagaca atggttgact gaaccagagt ctatgctagg agaagaagct ttaggggttt
    36061 accttaatgg aggtgtagtt tataattttg aacacccagc ttatacctat ggtgtaaata
    36121 ataaagaaag cttactcttt agcgaagtaa taaaagaatt ttttagatat gtaatagcgc
    36181 atccagcacc atccaaagaa aaggtacttg aggatacaaa agtattcata catggagact
    36241 attcaaataa aggaaatggt aagttctttg taaacgtaaa tactgataga gaacaaactc
    36301 cattatacat gactggtcgt tataatgtta ttccagctat tccaggtgtt ttaaaaacag
    36361 ataaattgaa agagtctgtt tctggtagcc gtattcagat taaggaaatc acttctccag
    36421 aatttagctc tactcaggct agaaaagaat acttaaataa gctgtatcct atgaattatg
    36481 aaggagatat ctttgctcag aaattagata atagatggtt tgtctataat tataaggtaa
    36541 atgagaatgt taaacagact gggaaattaa aatttaattc tttagaaatg gatgttgaat
    36601 ttgaacctca tacctatggt atttttgaga gaataagtaa tggattgaaa gtgaatttaa
    36661 ataattttag aacaaataaa gattcactat ggtctaatgc tcaagatgca aatcaggcaa
    36721 agaaactacc acaattgacc aagaaaggtg ccattaagtg gattgaagaa cattatatca
    36781 aagatactca gtttggagag aaaagggtta caaagatagt attaagaggt atagataaac
    36841 ttcctactat tcattcatta tcaggaacaa atgattccta tgatcagcca tctctcaatt
    36901 ttgatcagaa aaatcatatg gttaatatta ccattaacag taacggaaat cttgaattcg
    36961 aacttcattt ttagaaagga gtgagtttat gtctcaagat gaaaaattaa ttcgtgaaca
    37021 gatttgtgat gtttgtcata agatgtggca acttggttgg gttgctgcta acgatgggaa
    37081 tgtatctgtt cgattagatg aggataccat tcttgcaaca cctactggta tcagcaaaag
    37141 ttttattaca ccagaaaagc tggtgaagtt aaatcttaaa ggagagattt tagaagcaga
    37201 aggtgattac tgtccttcta gtgaaattaa aatgcacatt cggtgctacg aagaacgtga
    37261 ggatgttcgt tcagttgttc acgcgcatcc accgattgca acaggatttg ctcttgcaca
    37321 cattccttta gatacttatt cactaattga gagcgcgatt gtggtagggg caattcctat
    37381 aacgccattt ggagttcagt ctacaatgga agtgccagaa gcaattacac cttatctgcc
    37441 cgatcatgat gtcatgctat tagaaaatca tggagctctg actgtcggaa gcgatgtaat
    37501 tacagcatac taccgtatgg aaactttaga attagtcgca aagacaacct tccacggaag
    37561 aatgttactt tctacaaagg gcattgagga gcaagaaatt gctcgtccga ctttagaacg
    37621 tctattctca atgcgagaaa attataaggt tacaggtcgt cacccaggct accgtaaata
    37681 taatggcgat ggtagtatga aagaaacaga aaaataagag gaaaatagta tgattcaaca
    37741 tccacgtatt ggtattcgtc cgactattga tggtcgtcgt caaggtgtac gcgaatcact
    37801 tgaagtacaa acaatgaaca tggctaaaag tgtggcagat ttgatttcaa gcacattgaa
    37861 atatccagat ggggaacctg tggaatgtgt gatttctcca tctaccattg gtcgtgttcc
    37921 agaggctgca gcttcccatg agttgtttaa aaaatcaaat gtttgcgcaa caattacagt
    37981 tacaccatgc tggtgttatg gtagtgaaac tatggatatg tctccagata ttcctcatgc
    38041 tatttgggga tttaatggga cagaacgccc aggagctgtc tatcttgcag ctgtactagc
    38101 ttcacatgct caaaaaggga ttccagcctt tgggatttat ggtagagatg ttcaggaagc
    38161 taatgataca gctattccag aagatgtcaa agaaaaactt ttacgttatg cgcgtgcagc
    38221 tcttgcaact ggcttgatga gagacactgc ttacctatca atgggtagtg tttcgatggg
    38281 gattggtggt tctattgtaa atccggattt cttccaagaa tacttaggaa tgcgaaatga
    38341 atcggtagat atgacggagt tcacacgccg tatggaccgt ggtatttacg accctgaaga
    38401 gtttgaacgt gctatggttt gggtaaaaga acatatcaaa gaaggagttg accgaaatcg
    38461 tgaggatttg attctttcta aagaagagaa agaaaaacaa tgggaatttg ttattaagat
    38521 gttcatgatt ggacgtgact taatggttgg taacccaaga cttgctgaac ttggttttga
    38581 ggaagaagca gttggtcacc atgctttagt agctggtttc caaggtcaac gtcagtggac
    38641 agaccatttt ccaaatggag attttatgga aactttcctc aatactcagt ttgactggaa
    38701 tggtattcga aaaccatttg tatttgcgac agagaatgat tcactaaatg gtgtgtctat
    38761 gctctttaat tatctattaa caaatactcc acaaatcttt gctgatgtgc gtacttattg
    38821 gagtccagag gctgttgaac gtgtaacagg acatacttta gagggtcgtg ctgcagctgg
    38881 cttcttacat ctaatcaact ctggatcttg tacattggat ggtacaggtc aagctactcg
    38941 agatggcaaa cctgttatga aaccattctg ggagttggaa gaaagtgaag tgcaggctat
    39001 gcttgaaaat acagacttcc caccagcaaa ccgcgaatac ttccgtggag gaggattctc
    39061 aactcgtttc ttgacgaagg gggatatgcc agtaacaatg gtacgtctca atcttctaaa
    39121 aggggttggt ccagtgctac aaattgcaga aggttacaca cttgaacttc ctgaagatgt
    39181 tcaccatact ttagataatc gtacagatcc aggatggcca actacttggt ttgctccacg
    39241 tttgacagga aaaggtgctt tcaagtctgt ctatgacgtc atgaataatt ggggagctaa
    39301 tcacggagcc ataacatatg gccacattgg agcagacttg attaccttgg cttctatgtt
    39361 gagaattcct gtcaatatgc ataatgtacc tgaggaagat atctttagac ctaaaaattg
    39421 gtccttattt ggaacagaag atctagaatc agcagactat cgtgcatgtc agttgttggg
    39481 accactacat aaataaaact tgtttatata ggaggtgaac ttacgtccct cctatccttt
    39541 taaaaagatt tgttaaacaa ttcacaaata attgaaaacg aatacaaaaa gtaatataat
    39601 gatgttaaat agatagcgcg gaggcgcagg aggaaaatta tatggctata ttttatgttc
    39661 cggcagtcaa ccttattgga aaaggtgttg taaatgaagt gggtccttat atcaaggaac
    39721 ttggctataa aaaggcactt ttggttacag ataagtacat cgaaggcagt gatattttac
    39781 ctaaggtttt aaaaccactg gatacagaag gaatcgaata tgtcatcttt agcgatgtag
    39841 agccaaaccc tacttgtaag aatgtcacag atggggtagc tgctttgcaa gaacatggct
    39901 gtgattttat catcagtctt ggcgggggtt ctccacagga tgcagctagt tgtatttcta
    39961 tcatggctac aaatggtgga aaaccacagg attatgaagg gcttcataag tctgctaaaa
    40021 aaggccttcc tgttgtagct atcaatacta cggcaggtac atcagcagaa attaccatta
    40081 actatgtgat tactgatgaa gaacgcaagg ttaagatggt aatggttgac aagaatagcc
    40141 ttgccttgat ttctgtcaat gaccctgaac tcatgctttc caaacctcaa gccttgactg
    40201 ctgctactgg tatggatgct ctgactcacg ctgttgaagc tttggtaaca cctggtgctt
    40261 atgatgtaac caagaaactg tctattggtg ctattgagct tatcaaggaa tatcttcctc
    40321 gtgctgtagc aaacggacat gatattgaag cgcgtgaagg tatggtcaat gccatcttcc
    40381 ttggtggtat gagctttaat aatgctggtc ttggctatgt tcactcaatg gctcaccaac
    40441 tcggtgcagt atataatttg ccacatggtg tttgctgtgc catgttgcta ccagttatag
    40501 aacgtgaaaa tgctaaacgt gtaccagaag ctttccgcaa tgttgccaaa gccttgggac
    40561 ttcatgtaga aggtaaatca gatcaagaat gtgccgatta tgcgattgct gagattgaga
    40621 agctttctga gacagtaggt attcctaaga aactgactga acttggtatt gaagaaaaag
    40681 atttcgactt tgaatacctt tctaagaatg ccttgattga tgcctgcgca ccaggaaatc
    40741 catttatgcc aaccttagaa gaaacgattg ccttttataa agagttattt tagcaaggat
    40801 tagacgacaa taggacaatt cacctctaat tattgacatt tcaggaaaaa tcgcagtaaa
    40861 aacggcacag ccttctttaa atgtgctata atactagaaa aatacttgtg gaggttccat
    40921 tatggcaata tttttcatga tttttctgat tgtttgtgtg ctcctattgg tgatagtcac
    40981 actgagtaca gtttatgtgg ttcgtcagca gtcggtggcg attattgaac gctttgggaa
    41041 ataccaaaag gttgccaata gcggtattca tattcgcttg ccttttggga ttgactcgat
    41101 tgcagcacgg attcagttgc gcttgttgca aagtgatatt gtggttgaga ctaagaccaa
    41161 ggacaatgtg ttcgttatga tgaatgtagc gactcagtac cgtgtcaacg agcagagcgt
    41221 gacagatgct tactataaac tcatacgtcc agaatctcag attaaatctt atatcgaaga
    41281 tgctcttcgc tcttctgttc caaaattaac cttggatgaa ttgtttgaga aaaaagatga
    41341 gattgccctt gaagttcaac accaagtagc agaagaaatg accacttacg gctacattat
    41401 cgtgaaaacc ttgattacca aggtcgaacc ggatgcagaa gttaagcaat ccatgaatga
    41461 aatcaatgcg gcgcaacgta agcgggtcgc agcacaagaa ttggcggaag ctgacaagat
    41521 taaaattgtc actgcagctg aagccgaagc agaaaaagac cgccttcatg gtgtggggat
    41581 tgcccaacaa cgtaaggcga ttgtggatgg attggcagag tctatcaccg aactcaagga
    41641 agccaatgtt ggcatgacag aagaacaaat catgtctatc ctcttgacca accagtattt
    41701 ggataccttg aatacctttg cctctaaagg aaatcaaacc atctttttac caaatacgcc
    41761 aaatggtgtg gatgatatcc gaacacaaat cttgtcagcc cttcgcgctg agaagaaata
    41821 atagactaat actcttcgaa aatctcttca aaccacgtca gcgtcgcctt gccgtatatc
    41881 tgcaacctca aaacagtgtt ttgagctgac ttcgtcagtc ttatctacaa cctcaaaacg
    41941 gtgttttgag caacctgtgg ctagtttcct agtttactat ttgattttca ttgagtacaa
    42001 agagcttggc aacaggctct ttttgtattg cgtttattaa gaaaaacaaa aaacatagat
    42061 atacatttaa ctaaaaatta ttgtatgtta tctcccttaa ttaggaatga taagggaata
    42121 actagaaaga tttgtgaata caaactattt ctgatataca aaatatacag taataatgaa
    42181 tgatgggaga tgggatgaaa gaatttcaat ttgagagaaa gcagcgtttt tctttgagga
    42241 aatatgcaat aggagcttgt tcggtcttgc taggaacgag tttatttttt gctggtatgg
    42301 gtgctcagcc tgtacaggat acagaaacga gttcagcact aatttcaagt cattatttgg
    42361 atgagcagga tttatctgaa aagctgaaat ctgagttgca atggtttgaa ttagaaaaca
    42421 agcttttgaa cttatgggag cattaggtta ctatgaagga tttgttcctt atgtttcaaa
    42481 tcaatacaaa aaccaagctg aagaagaaga caaaccgcta tctgataaat atattttcga
    42541 aaaaatctta ggaaaaacat atgcagcctt caaaaaagat caaattaatg agcgtgtcga
    42601 gaaattaggt aagttaaaac ctattacaat aaattaggta agttaaaacc tattacaata
    42661 aattacaacg gaaaatcaga agtaattgat agtaaagaaa aattacaaga gcttatgaat
    42721 aaagccgtta aagacgaagt ggctcaaata tagtaaaatg aaataagaac aggacaaatc
    42781 gatcaggaca gtcaaatcga tttctaaaaa tgttttagaa gtagaggtgt actattctag
    42841 tttcaatata ctataaaatc aggcaatacc acggttaaaa agtttgagtt tatcgaaaca
    42901 ccagtgcaaa aactgaaaaa agcgatttat aaagctcatc tcaaagattc agatgacttt
    42961 agaccagaaa catccacacc aaatcttttt gaaagctgtt tgaagctttg tccttgcttt
    43021 cttagttcat agatctgaac tttatcttca taactcaatt tcataataaa acaccccaaa
    43081 agttagattt attctgtcta acttttgggg tgcagttcat taatcggtcg attttttttg
    43141 gtagaaacag ttgcctgatt aagttgcaag tcgatagacg gcttcggcat aaatatccat
    43201 agcacggtac aaatcttcta gaacggcaca ttcatttgcc tgatgttctg tctgcttcgc
    43261 tcctgggaat aaggcgccga aggctacaca atttggcatg gtgcgagcaa aagtggcacc
    43321 accggatgaa atagcaggac tgttatcgcc agtcttttct tggtagattt gcatcagtgt
    43381 gctaacgagt ttactgtctt ctgcgacgta tagaggcgct agatagtcaa actcttcgta
    43441 gcggagttgg tagttttgtg cacatcttgt aagcaactct actagttctt ccttgtcagc
    43501 taagacagga gtccgaatgt caatacggat ttcagaacgt tcatgattga tcatgagacc
    43561 tgcgacatta aaggataggt gaccagaagg ttcatctgct atatcaccaa agatttgtct
    43621 tcctgtgccg tcttgacctg cttgtgttgc aagaaaactg agagcagggt gttcttggag
    43681 aggagcaaga atggtagcta gtcggatgac agcattgata ccttgactag catccttagc
    43741 atgctttggc actccgagaa ccgttacggt ttgttcagtg gattggtaat cataaccagc
    43801 ttctttgaga ccgttacaaa cctgttcata gaggggacct tggtagttgg ccttgtctgg
    43861 tacaacgtta aaggcgcctc ctacttcaag ctctagttga tccgatccag ggccatgaag
    43921 tttgacctgt agaagccctt tttcagcata ggtcagagga aaagatgagt caggtgcaaa
    43981 gcccatactg gcctgttctt cgatggtatt gtagcgtgcc atgcagcgcc agagggtttc
    44041 ctcatcggta ccaaagataa agcgtacgcg ctttttgaac tgaatacctt ggtccagcaa
    44101 gctttttact gcatagagag ctgcgagcga agggccttta tcatcttgga caccacgtcc
    44161 gaatacccag ccgtctttga tagttgcttc aaatggcggt gtctgccaat ctgcttcatc
    44221 acctgatgga acaacatcca aatgacagag aatggccaga agctctgctc cctgaccgat
    44281 ttctgcatat ccgtaataac ctttagggtc aagataggta gtgaaaccta tgtctcgaca
    44341 aatctctaaa gttttttcta ggacatcttg gattgcttgt ccaaaaggtg ttccattttc
    44401 tccttcattg agtactgaag gataggaaat caaggttttt aatgatataa gaaattcatc
    44461 tttaacttga tttgttatat ctattttcat ggaatcacct cactcactat tttataggaa
    44521 tggaaggaag gttccaagga gaagaagggc gatggtcact acaataatag cgactacgag
    44581 tttgcccatg aatttccacc aagtaccaat gttgatacgt ccaagtgcaa gagctcccat
    44641 cacaatacca gatgttggtg caatcaagtt caagacacct gaagcagatt ggtaagcagt
    44701 gataatcaag ctaggacgga catttacaaa ttctccaagt ggagccatga tacccatagt
    44761 tgcgctggca agaccagatg aagatgggat caagaatgac ataggtagat agaagatata
    44821 agttacaacg ataaagactt gtgaagatag accgctcaag ccttctttac cccagttgag
    44881 gattgtatcg gtaatcatac cgtcgttcat gataacttga ataccacgag caatcgctac
    44941 gatcaaggca acactgagca agtcagcagc accattcatg aaggaagaga taatcttatc
    45001 ttctttaaga ccataaataa caccaatcag gatacccata aaggcaaaga gcattgcgcc
    45061 ttctgggaag taccaagtac ctagtgcaga agtagatgaa ccgacaatat taccaataac
    45121 tggaagacca gtcaaccaag tattaaagtc atcaaaaatg gtaacgccaa ggtctgtcca
    45181 tggaatgaag ctcaatacca tcaagatgaa tgtcaacaca aataagaaga gaactgattt
    45241 ttgtttgctg ctaagtgtag attctacaga tgaagattct tctacgttaa agtgtttcaa
    45301 atcttctttg cgagtactat aaaccagtga cttagtcgga tctttttgaa tcttatccgc
    45361 ataacggtaa acaaaccaag tactaagagc agtcaaggta acccagaaga tcagacgaag
    45421 tacgataccg tcccctgtac caactcccgc agtcgctgaa gcaatacctg tcgcaaatgg
    45481 attcagagta gatgccaaac agccgatttg agaaccgagc aaaataattg caacaccagt
    45541 caggctatca aaaccaacgg ccatcataac tggcacaagg agtggataga aggccattgt
    45601 ttcttcaccc ataccataag ttgtaccacc gagggcaaac aaaggcatca ataccaaaat
    45661 taacattttt tcgcggccct tatacttctt cacgatagag gcaatcccta cgtcaagagc
    45721 accagttttg ttgacaatgc caaggaaacc accaaccata aggatgaaga aggctacatc
    45781 aatcgctgcg ctcgtttctt taatgagcga accttcctct ggatgagtac ctagcatagc
    45841 ccgaatcggt gccatgagga catcccaaat cccttgtgga ttttgaggct gagcctcgta
    45901 aataccttct ataaaggccc ccgcagggat aaaccaagtt agcacggcca taatagcaat
    45961 gattatcaat aatacggtgt aagatgaagg catcttaaac ccttttttag ctttttcact
    46021 catttgtttt tcctcctgat gtctaacaaa gtgtaaaaaa ccaactactt tcttaaataa
    46081 acattcaaga aaacgctttc tatttatatt tgttttacca tattaaagtc taaaactagt
    46141 atcttttgaa atattgtaca tgttttcaag aataatttct aatttgatat aaagatacta
    46201 gaaatagaat acatcttatt agtaaaacaa cttatccttt ttcaataatt gttccgcttt
    46261 cagattcaat caaggcgcct agattttcaa gggaagtaat aactgctttt ccttctggac
    46321 gaccattgac aaaagcgata gctgcttcta cttttggaag catgctacct ggtgcaaact
    46381 gatcttgttt gatatattct tccagctggg caacattcac atgttccaat ttttcctggt
    46441 ttggcttgtt gtagttaaca aatacataat ctacacctgt caaaacgatg aagaggtctg
    46501 catcaaccaa ttctgccaaa cgttgggaag cgaagtcttt atcaataacc gcttcgacac
    46561 cagtcaaatg tccattgttt tctttgacga cgggaatacc gccaccacct gcagctacga
    46621 cgacttgacc attatttaaa agagtacgga tggtttcaat ttctttgatg tcaacaggtt
    46681 ttggtgaggc aacgacctta cgccagccac ggccagcatc ttccttgaaa gtcgctccgc
    46741 tcttttcggc ttctgctttt gcttcttctt ctgaatagaa aggaccgatt ggtttactca
    46801 agttaacaaa agctggatca tttttatcta cgataacttg cgttacaaca gaggcaacat
    46861 ttttttcgat gccttcatcc aagagagcat tttgcaaagc atttttcaac cagaaaccga
    46921 tgctaccttc tgtcatagcg acaagtgagt cgagtgggaa ggcagggttc ttttcagagt
    46981 ctgatgccaa atgttggagc aagagattcc caacttgagg tccattaccg tgagtgataa
    47041 tcaaatcatc tccattttta atcaatttta caagatgctt agctgtttca actaaagctt
    47101 cttgttgagc ctttgctgat gggtcagaag aaagaatcgc atttcctccc aaagctacta
    47161 caattttacg atttgccata aattctcctt tatcacactc aatagaatgc gtttagattt
    47221 caatttaatg atttttcaca tattttataa gaaataatag attaccatta cataaaagag
    47281 gaccggacta aagctattag tcgcagccct catagctgtt ggtagacggt ttattatcta
    47341 aaattatact ttaggaatat aaaggttacc aagtgtagca gccataacag ctttgatagt
    47401 gtgcatacgg ttttctgctt gatcgaagtg gcgagcgtac ttgctgcgga agacttcgtc
    47461 tgttacttcc atttcttcta caccaaattt ttcagcaacg tctttaccat aaacagtgtg
    47521 agtatcgtgg aatgctggca agcagtgtag gaagatcaag ttttcattgc ctgctttttt
    47581 aactaagtcc atattgactt ggtaaggttt aagaagagct acacgttctg cgaatttgtc
    47641 ttcttcaccc attgataccc aaacgtctgt gtaaagaacg tctgcatctt taactgcttc
    47701 atcagcatct tcagtgatga gaacatgtgc gccactttct ttagcaaatc cttctgccaa
    47761 ttcaacgatt tctttttctg ggaagagttc ttttggtgag aagatgtgaa cattgacacc
    47821 aaggatagca cctgttacga gcaagctgtt ggcaacgttg ttacgtccat caccacagta
    47881 taccaatgtc aagccttcca agcgaccgaa gttttcttga acagtcaagt agtcagcgag
    47941 catttgagtt gggtgccatt cgtcagttag accgttccat actggaacgc ctgagaattc
    48001 tgccaattct tcaaccatac gttggctgaa tccgcggaat tcaatcccgt caaacatacg
    48061 tcccaatact ttagcagtat cttcagtaga ttctttttta cccaactgaa tatcatttgc
    48121 tccgaggtat tctgggtgag caccaaggtc gatagccgca gttgtaaagg ctgcacgagt
    48181 acgagtagat gttttttcaa ataggagagc gatattcttg ccagcaaggt agtggtgttg
    48241 aatattgcgt tttttcaaat ctttcaagtg agctgaaaga ccaataaggt attctaactc
    48301 tgcacgggta aagtcttttt ctgctaagaa gctgcgtcct tggaatactg aatttgtcat
    48361 tttattattt cctctttcta ttttttacat tttctattga cgaataccga acagcgatta
    48421 cacttcttca cgttcaaatg gcatagacat acaacgaggt ccaccacggc cccgaaccaa
    48481 ttcacttccg cgaatcttaa tcaagcgaag cccgtattct tccaaaatct tattggtcac
    48541 ggtattgcgg tcataaacaa ctaccacacc aggtgcgatg gtcaaagtgt tagaaccgtc
    48601 gttccattgt tcacgcgcag ctgctacgat attgccacca ccgcaacgaa tcaaatgaac
    48661 tttttctaca ccaaggtttt gagcaagaag ttcagctaag tcacctttct cttcaacgat
    48721 tttaagtttt tcgttttcgt aagtaactga gtaaacgtga aggtcgcctt cgatttctgg
    48781 gtgaatagtg aacttgtcat agtctaccat agtgaagaca gtatccaagt gcatgaattt
    48841 acggttgtta gcaaattcaa aggccaaaac tttcttgaag ccaacatttt tcttgaagat
    48901 gttgaccaaa agtttttcga tagaagctgc gtctgtacgt tgagagatac ctactgcaag
    48961 gacgtcttta gaaagaacta gctcgtctcc accttcgata cgcgtatctt cttcacggtt
    49021 gtagaccaaa tccacttttc cgccatagac tgggtggtat ttgaagatat acttaccgta
    49081 gagtgtttca cggttacgag tgtctgcaaa catgtggtta agcgatacgg cgtttccaat
    49141 tgttgcaaat gggtcgcgag tgaaatagag gtttggcatc gggtcaattg caaatggata
    49201 atctgattca actaagtcag ttagatcttt agcttcgtca ggaatttctg gcaattcaac
    49261 tttttgaatc ccagccattg ttttttcaac caattcttgg ttgtccttga tgccgtgaag
    49321 caattcacga atagcaacct tggtttgacg atcacggatg ttggcttcgt ctaagtattc
    49381 ctcgataaat tgatcgcgga tttctggaga ggtcaatgat tcagcagcga gttgttctag
    49441 gtagagaacc tcaattcctt catcgcgaag agcttgggca aatgcatcat gttctttttg
    49501 agcatcttcc aagaaaggaa tatcatcaaa aagaagcctt tcaagatagt ccggcaacaa
    49561 gttttctaac tccttgcctg gacggtgcaa cataactttt ttcagtttcc caatttctga
    49621 gaagacctga attggatgag aagacatgta ttttcctcct taaaaatttt gacttggcac
    49681 cattttgggt accgcttaca tgtatgttat aacgcaattc ctaggtaatg tcaatggcta
    49741 taatttctcg gaaaataata taaattatga tgtttagcac aattttatgt tattatacat
    49801 aacataggat agaatacata gatacaaatg cataaacttc tataaaaagg atataaaatt
    49861 tttttaaaaa atttttcaaa aaatatacaa atgaccaaaa agtgtccaat tatcatctgg
    49921 ttatcacttg gatctgtata aagagaaatg tttgtgtgaa aggataaaaa gatgcaacat
    49981 tcttttgaag atagattttg gagaagcatt tcttgctcaa ttgtacaaat tatagaatct
    50041 tttctgagta tttaggaaga gataattatc ttattgaccc tctttttatt ttttgttata
    50101 gtcgacgagg tgatagttta gaataatcac ttattcacaa tctgtggaaa agtctggaga
    50161 gtgaatggtc ttcacacaat gacctgaaag aagcctgaga ataattatgg agagtagcat
    50221 tctgagaggt gttagcagaa ccatatgaca gagctgtttg aagagggaat attgaggaga
    50281 aaaatcctga gcctaccagt tggagttgga aagagctggc ggttagatca ttttttatta
    50341 tccacaacct gtggataacc ttgtgaacaa gagaagttgc taaagaagga gatatataac
    50401 gatgaagaaa atcaaaccgc atggaccgtt accaagtcag actcagctag cttatctggg
    50461 agatgaacta gcagctttta tccacttcgg tcctaatacc ttttatgacc aagaatgggg
    50521 gactggacag gaggatcctg agcgctttaa cccgagtcag ttggatgcgc gtgagtgggt
    50581 tcgtgtgctc aaggaaacgg gcttcaaaaa gttgattttg gtggtcaagc accacgatgg
    50641 ctttgtcctt tatccgacag ctcacacaga ttattcggtt aaggtcagtc cttggaggag
    50701 aggaaagggc gacttgctcc ttgaagtatc ccaagctgcc acagagtttg atatggatat
    50761 gggggtctac ctgtcaccgt gggatgccca tagtcccctc tatcatgtgg accgagaagc
    50821 ggactacaat gcctattatc tggctcagtt gaaggaaatc ttatcaaatc ctaactatgg
    50881 gaatgctggt aagttcgctg aggtttggat ggatggtgcc agaggagagg gcgcgcaaaa
    50941 ggttaattat gaatttgaaa aatggtttga aaccattcgt gacctgcagg gcgcttgctt
    51001 gattttttca acagaaggca ccagtatccg ctggattggc aatgaacgag ggtatgcagg
    51061 tgatccactg tggcaaaagg tgaatcctga taaactagga acagaagcag agctgaacta
    51121 tcttcagcac ggggatccct cgggcacgat tttttcaatc ggagaggcag atgtttccat
    51181 ccgtccaggc tggttctacc atgaggatca ggatcctaag tctctcgagg agttggtcga
    51241 aatctacttt cactcagtag ggcgaggaac tccactcttg cttaatattc cgccgaatca
    51301 agctgggctc tttgatgcaa aggatattga acgactttat gaatttgcga cctatcgcaa
    51361 tgagctctat aaagaagatt tggctctggg agctgaggta tctggtccag ctctttccgc
    51421 agactttgct tgtcgccatt tgacagacgg ccttgagacc agctcttggg caaacgatgc
    51481 agacttgccc atccagttag aactcgattt aggttctcct aaaacttttg atgtaattga
    51541 gttaagagaa gatttgaagc tagggcaacg aatcgctgct tttcatgtgc aagtagaggt
    51601 ggatggtgtc tggcaggagt ttggcagggg cttcacagtt ggtcataagc gcctcttgcg
    51661 aggtccgcta gtagaggcac aaaaggtgcg cgtgatgatt accgaggcac aatctatccc
    51721 tgtattgacc aagatttccc tttataaaac tcctggatta tcaaaaaaag aagttgttca
    51781 ggaactagca tttgcagaaa aaagcctagc tgtggcaaag ggagagactc ttcattttag
    51841 gattgaacgt agtgaaagta gctcctcttt agaagctaag atttcgattc aaccggggac
    51901 aggtgtccat ggtgtcgcct atcaggatga gattcaagtc cttgcgtttc aagctggtga
    51961 gactgaaaaa agtctgacgc taccaacctt gtatttcgca ggagataaaa ccttggattt
    52021 ctatctgaac ctaacggtgg atggtcagct tgtggatcaa cttcaagtcc aagtttcata
    52081 aaagaagaac ctttgcgcga tgcaaaggtt cttttggtta ttagtgattt ggtagccagc
    52141 tgagggtgaa agttagttgt tcagctttta agaggtcttg gtgttgaata gttgatacga
    52201 gtattttgtc cagtcggcat tctttgacaa agttaaaatg gttgtggttt tgtttagtat
    52261 ggatatccag ccatttatct tctttagcga ggtagactcg tagatggtca aagagaggga
    52321 ttccgaggtc atagcttggt tttcctggac aggttggata aaatccgaga gctgaccaga
    52381 tgtaccaagc agagagactg ccattgtctt catctccagg ataggcttcc caacttgggt
    52441 gaaaagcttt ctgacggagc gtcttgataa gaagggcagt gtagtcaggg taatcgctgt
    52501 agcggaagag ataaggaatg tggaaactag gctggttgga aatggctatt tgtccaaaag
    52561 gagcagtagc catctcgctc atttcgtgaa tttcgtaacc atagcctgtt gtttcaaaga
    52621 ggggagcatc ttgacaggct ttcaaaagat agttgctaaa ggtttctttt ccacccatca
    52681 gttggattaa gccagggatg tcgtggagaa cgcctaaagt agcttgaatg gcagagcatt
    52741 cagcgtagtc tcgcccccaa ctataaggag agaagtcagg gtgaaagttt ccttgattgt
    52801 ctcgtgctcg catgtaacct gtctcagcgt caaatagctg gcggtaattt tgtgaagcag
    52861 ccttgtaggt ttcagcgatt tctatgtttt ttagtttttt ggcacagttg gcgatacaaa
    52921 agtcactata ggcatagtct agagtatggc taacactttc gtggtggtcg gtagagaggt
    52981 aacctagttc ttggtattgg gctagtccgt ggcggccatt gatgccgaga gggtcggctt
    53041 tgctggctgt ttcgagcatg gcttggaaga gttctccttc taggtcgggg gccatgtcct
    53101 tgcaggcgct atctgcgata ataccgtcta aaagtgtacc tggcatcata ccccgttcat
    53161 ctggagccag ccattttgga aggaaactag tatcgcggta gctattgagg aaaccttcta
    53221 aaaagcgttg atagtgctcc ggtatgataa gggcaaagag ggggaaggtg gtgcggaagg
    53281 tatcccagaa accattgttg ctaaagagga caccaggctt gacagtacca gtagccatat
    53341 ccatgtggat ggcttgccct gactcatcaa cctcataaaa agtctgtggg aagaggaaga
    53401 gtctgtagag acagtggtca aagaaggttc ggtcagcctc tcctgtctct ataatgtcaa
    53461 aacgatggag gagattttcc caatccgctt gggcacttgc tttacagcta tcaaaatctt
    53521 cttgaggtag attaagcagt gcttgagaag gagagatgaa agaagtggct agttgcatct
    53581 cggtttgact acttgctaag tcaattcgcc agtctccccc ttcttggctg atagcaagaa
    53641 tatccgtgtt catttgcagg gcagtgaaca tcgttagcga atttttgtta gtttcagttt
    53701 taccttcttg tcgcagggca agagtccgct tatctacttg ctctacggtc agttcatctg
    53761 ctgcgtgaag atagagggag agggctttgc cttgcttttg attcaaacga atagaagcac
    53821 catagcaagt cggtgtgagc tgggtttcaa tctgataacg cagagaaaag agcttcaaat
    53881 agtgaggctg gaagcaagct ttatctatat cataagaaga ctggcggtga aagaggctgt
    53941 ctccacccag ttgactggtg acaggtgtca gaaggagcca agagtagtcc ccaatccaag
    54001 gactgggctg gtgagttaat cgaatcccct gaaagatagg cagatgcgga tcaaaaaacc
    54061 aagatccatc ctggtcactg gtctggggca caaagtaatt catcccaaaa ggcacgcctg
    54121 tgtatggcag ggtatttccc cgagagaagg catgcttgct agcagtacca aagcgggtat
    54181 cgatggtttc aagtagtggt ttcatagtct ttcctttagc tgtttttcta cattatatca
    54241 gaaaaagagg gcctttagaa aaggagtttc aaagataact attttgtaga aaaatgacta
    54301 tcatttgtgt atgtattttc tgtctcaaaa gctatatact gaacatgaaa cttgtttgaa
    54361 agagggaatt gcacgatgat ttattcgaaa gaaattgtta gagaatggct agatgaagta
    54421 gcagagcggg ctaaggacca tccagagtgg gtggatgttt tcgagcgttg ctacaccgat
    54481 accttggaca atacggttga aatcttagaa gatggttcaa cttttgtctt gactggggat
    54541 attcctgcca tgtggcttcg agattcgaca gcccaactca gaccctacct tcatgtagct
    54601 aaaagagatg ccctcctgcg tcagaccatt gcaggtttgg tcaaacgtca gatgaccttg
    54661 gtactcaagg atccctatgc taactccttc aacattgagg agaactggaa agggcaccac
    54721 gagactgacc acacagacct taacggctgg atctgggagc gcaagtatga ggtggattca
    54781 ctttgctatc ctttgcagtt ggcttatctc ctctggaaag agactggcga gactggtcag
    54841 tttgatgaga tttttgtcgt agcgactaag gaaattctcc atctatggac agttgaacaa
    54901 gaccacaaga actctcctta tcgttttgtc cgagatacgg accgtaagga agacaccttg
    54961 gtaaatgatg gctttggacc tgattttgca gtgacaggaa tgacttggtc agcctttcgt
    55021 ccgagtgatg actgttgcca gtatagttac ttgattccgt caaatatgtt tgctgtagta
    55081 gtcttgggtt atgtgcaaga aatcttcgca gcattaaacc tagctgatag ccagagtgtt
    55141 attgctgatg ccaagcgtct tcaggatgaa atccaagaag gaatcgaaaa ctacgcttac
    55201 accaccaaca gcaagggcga aaagatttac gcttttgaag tagatggcct aggaaatgcc
    55261 agcattatgg atgatccaaa cgtaccaagt ctactagctg cgccctatct gggctactgt
    55321 tcggtcgatg atgaagtgta tcaagctact cgccgtacca ttctgagctc tgaaaatcca
    55381 tatttctacc aaggagaata cgctagcggt ctcggaagtt ctcatacctt ctatcgctat
    55441 atctggccaa tcgccctttc tatccaaggc ttgacaacaa gagataaggc agagaaaaac
    55501 ttcttgctgg atcagctggt tgcctgcgat ggcggtacag gtcttatgca tgaaagcttc
    55561 cacgtggatg acccaactct ctactctcgt gaatggttct cctgggctaa catgatgttc
    55621 tgtgagttgg tcttagatta cttggatatt cgctaagggg ctcgctttag ctcaaccgat
    55681 tcttatcaga atcacaagtt tacatttaaa acgttaaaat ttaaatttag aatgaggttt
    55741 tacttcatgg aaaatgttgt tgtacatatt atctcacata gtcactggga ccgtgagtgg
    55801 tacttgcctt ttgaaagtca tcgtatgcag ttggtggaat tgtttgacaa tctctttgat
    55861 ctctttgaaa atgaccctga gttcaagagt ttccacttgg atggacaaac tattgtcctt
    55921 gacgactact tacaaattcg ccctgaaaat cgcgacaagg tccaacgcta cattgacgag
    55981 ggcaagctta aaattggtcc cttttacatc ttgcaggatg attatttgat ttcaagtgaa
    56041 gccaatgtcc gcaatacctt gattggtcaa caagaagctg ccaaatgggg taaatcaacc
    56101 cagattggct actttccaga tacctttgga aatatgggac aagcgcctca aattcttcaa
    56161 aaatcaggca ttcacgtggc ggcctttggt cgtggtgtga agccgattgg atttgacaac
    56221 caagtccttg aagatgagca gtttacatcc cagttttcag aaatgtactg gcagggtgtg
    56281 gatggtagtc gtgttttagg tattctcttt gccaactggt acagtaatgg gaatgaaatc
    56341 ccagttgaca aagatgaggc cttgaccttc tggaaacaaa aattgtcaga tgtgcgtgcc
    56401 tacgcttcga ccaaccaatg gttgatgatg aacggctgtg accaccagcc tgtacagaaa
    56461 aatctgagcg aagccattcg tgtggcaaat gaactcttcc cggatgtaat ctttgttcat
    56521 agttcttttg atgaatatgt tcaagctgta gaaggtgctc ttcctgaaca cttatcaact
    56581 gttacaggtg agttgaccag tcaggaaaca gatggctggt acacacttgc caacacttct
    56641 tcatcccgca tttacctaaa acaagccttc caagaaaata gcaacctcct agagcaagtg
    56701 gtagaaccct tgactattat cactggtgga cacaaccaca aggaccagtt gacctatgct
    56761 tggaaaacac ttttgcagaa tgcgccacat gatagtatct gtggctgtag cgtggacgaa
    56821 gttcaccgcg agatggaaac gcgttttgcc aaggtcaacc aagtaggaaa ctttgttaaa
    56881 agtaatttgc tcaacgagtg gaagggtaaa attgctacgg ataaggctca aagtgactat
    56941 ctctttactg tcattaacac aggcttgcat gataaggtcg atactgtcag cacagtgatt
    57001 gatgtggcga cttgtgattt caaggaattg cacccaacag aaggctacaa aaagatggct
    57061 gctcttatct tgccaagtta ccgtgtggag gacttggatg gtcgtcctgt agaggctaca
    57121 atcgaagacc tcggagctaa ttttgagtat gatttaccaa aagacaagtt ccgccaagct
    57181 cgtattgctc gtcaagtgcg cgtgaccatt ccagttcacc tagcgccgct ttcttggaca
    57241 accttccaat tgctggaagg aaaacaagaa caccgtgagg gtatttacca aaacggagtg
    57301 attgatacac cattcgtaac ggtgagtgtg gatgacaaca tcacagtcta tgacaagaca
    57361 actcacgaag cctatgaaga ctttatccgc ttcgaagacc ggggtgacat cggaaacgag
    57421 tatatctatt tccaaccaaa aggaacagag ccaatctttg cagagcttaa gggccacgag
    57481 gtcttggaaa acacagcttg ctatgctaaa atcttgctca aacatgaatt gaccgtgcct
    57541 gtcagtgcgg atgaaaagct agaagaagag caacaaggta tcatcgagtt tatgaagcgt
    57601 gaggctggac ggtcagaaga attgacaaac attcctctgg aaactgagtt gactgtcttc
    57661 gttgacaatc cacaaatccg cttcaagact cgctttacca acactgccaa ggatcaccgt
    57721 atccgtctct tggtcaagac tcataacacg cgtccaagca atgattctga aagcatctat
    57781 gaggtggtga cacgaccaaa caaaccagca gcttcatggg aaaatcctga aaatcctcaa
    57841 caccaacaag cctttgttag tctgtatgac gatgaaaaag gtgtgactgt atccaacaag
    57901 ggattgaatg aatacgaaat ccttggggat aacaccattg ccgtgaccat tttgcgtgca
    57961 tcaggtgagc taggtgactg gggctacttc ccaacgccag aagcacaatg cttgcgggag
    58021 tttgaagtcg agtttgcact tgaatgccac caagcccaag aacgcttctc agcctatcgt
    58081 cgtgccaaag ccttgcagac accgtttacc agccttcagc ttgctagaca ggaaggaagc
    58141 gtggttgcga ctggtagcct cttgagccat tctgttctca gcataccgca agtttgtcca
    58201 acagccttta aagtggcgga aaatgaagaa ggctatgtcc tccgttacta taatatgagt
    58261 caagaaaatg tgcgcatatc agaacatcaa caaaccattc ttgacttact tgagcgacca
    58321 tatccagttc attcaggact attggctcca caagagattc gtacagaatt catcaaaaaa
    58381 gaagaaattt aatttcaaaa agtaaacatc aaaagaaagg aggggcgaaa aagtaagaac
    58441 taactgctga ttcgcccctt tttatggtaa aaacaatgac cattgcaacg attgatatcg
    58501 gagggactgg gattaagttt gccagtctga ctcctgatgg gaaaatactg gataagacaa
    58561 gtatttcaac gcctgaaaac ttggaggatt tactagcgtg gctagatcaa cgcttgtcag
    58621 aacaggatta cagtgggatt gctatgagcg ttccaggtgc ggtcaatcaa gagacaggtg
    58681 tgattgatgg cttcagtgcg gtgccctaca tccatggctt ttcttggtat gaggcgctta
    58741 gctcttatca gctacctgtc catttagaaa atgatgccaa ctgcgttgga gtcagtgaac
    58801 tactagctca tccagagctt gaaaatgcag cctgtgtcgt gattgggaca gggattggcg
    58861 gagccatgat tatcaatggt agacttcatc gaggtcgcca cggtctgggt ggagaatttg
    58921 gttacatgac aacccttgcc cctgctgaaa aacttaataa ctggtcgcaa ctagcatcaa
    58981 ctgggaatat ggtacgatac gtgattgaaa aatctggtca tactgattgg gacggtcgca
    59041 agatttacca agaggccgca actggtaatg ctctttgtca agaagccatt gagcgcatga
    59101 accgcaatct ggcgcaaggc ttgctcaata tccagtatct gatcgatcca gatgtcatca
    59161 gtctgggtgg ctctatcagt caaaatccag attttatcca aggtgttaag aaggctgttg
    59221 aagactttgt cgatgcctac gaagaataca cggtcgcacc agttatccag acctgcacct
    59281 atcacgcaga tgccaatctc tacggtgccc ttgtcaactg gctacaggag gaaaagcaat
    59341 ggtaagattt acaggactta gtcccaaaca aacgcaagct attgaggttt taaaaggtca
    59401 catttctcta ccagatgtgg aagtggctgt cactcagtct gaccaagcct ctatctctat
    59461 cgagggtgag gaaggtcact atcaattgac ctaccgcaaa cctcaccaac tttatcgtgc
    59521 cttatccttg ttggtaacag ttctagcaga agctgataaa gtagagattg aggaacaagc
    59581 agcttacgaa gatttggctt acatggttga ctgttctcga aatgcggtgc tgaatgtggc
    59641 ttctgccaag cagatgattg aggtcttggc tctcatgggc tactcaacct ttgaacttta
    59701 catggaagac acttaccaga ttgaagggca gccttacttt ggctatttcc gtggagctta
    59761 ttcagcagag gagttgcagg aaatcgaagc ctatgctcaa cagtttgaca tgacctttgt
    59821 accatgcatc cagaccttgg cccacttgtc ggcctttgtt aaatggagtg tcaaagaagt
    59881 tcaggagctc cgtgatgtgg aggatatcct ccttatcggc gaagaaaagg tttatgacct
    59941 gattgatggc atgtttgcca ctctgtctaa actacaaact cgcaaggtca atatcgggat
    60001 ggacgaagcc cacttggttg gtttgggacg ttacttgata ttgaacggtg ttgtggatcg
    60061 tagtctcctc atgtgccaac acttggagcg cgtgctggat attgctgaca aatatggttt
    60121 ccactgccag atgtggagtg atatgttctt caaactcatg tcagcggatg gccagtacga
    60181 ccgtgatgtg gaaattccag aagaaactcg tgtctaccta gaccgtctca aagaccatgt
    60241 gactctggtt tactgggatt attatcagga tagcgaggaa aaatacaacc gtaatttccg
    60301 caaccatcac aagattagcc atgaccttgc atttgcaggg ggagcttgga agtggattgg
    60361 tttcacaccc aataaccatt tcagccgtct agtggctatc gaggccaata aagcctgccg
    60421 tgccaatcag attaaagaag tcatcgtaac gggttgggga gacaatggtg gtgaaactgc
    60481 ccagttctct atcctaccaa gcttgcaaat ctgggcagaa ctcagctatc gcaatgacct
    60541 agatagtttg tctgcgcatt tcaagaccaa tactggtcta acggttgaag attttatgca
    60601 gattgacctt gccaacctct taccagacct accaggcaat ctcagcggta tcaatcccaa
    60661 ccgctatgtt ttttatcagg atgttctttg tccgattctt gatcaacaca tgacacctga
    60721 acaggacaaa ccgcacttcg ctcaggctgc tgagacgctt gctaacatta aagaaaaagc
    60781 tggaaactat gcttatctct ttgaaactca ggcccagttg aatgctattt taagtagcaa
    60841 agtagatgtg ggacgacgca ttcgtcaggc ctaccaagcg gatgataaag aaagtttaca
    60901 acaaatcgcc agacaagaat taccagaact tagaagccaa attgaagact tccatgccct
    60961 ctttagtcac caatggctga aagaaaacaa ggtctttggt ttggatacag ttgacatccg
    61021 tatgggcgga ctcttgcaac gcatcaaacg agcagaaagc cgtatcgagg tttatctggc
    61081 tggccagctt gaccgcatcg acgagctgga agttgaaatc ctaccattta ctaacttcta
    61141 cgcagacaag gatttcgcag caactacagc taaccagtgg cataccattg cgacagcttc
    61201 gacgatttat acgacttaat actcttcgaa aatctcttca aaccacgtca gcttccatct
    61261 acaacctcaa aacagtgttt tgagcagcct gcagctagct tcctagtttg ctctttgatt
    61321 ttcattgagt ataaaaacaa gaacaccttg cttggcgcag ggtgtttcgc gtgaaacaga
    61381 agaattatct ggtttcaaat gctacagtta aaattagtaa aacaagaaat agaagctgaa
    61441 aagccagcat ctgtagaagc ttggatcatt tccgtcaaat taaaaaaggt tgctaccgac
    61501 atatatagat tccaaaaaca aaaacgttag cggaactagc agatgtgatt ttatggagtt
    61561 tcgattttgc aaatgatcat gctcacgcat ttttcatgga taatgttgag tggagtcatg
    61621 cagattctta ctttcttagc tttgttagtg acgatgttga agaacgttac acagaaaatg
    61681 tctatctgga tagcctaagt gtcaaacaaa aatttaagtt tattttcgac ttcggtgatg
    61741 aatggcgttt tgaatgccaa gtactgagag aaatcgagac agaggacgaa gaagcttatc
    61801 tcgtacgttc ggttggaacg tcgccagaac aatatccaga ttatgatggt tttgactatg
    61861 aagaatggta aaattgaaat ctaaaaaaca attggaatca gtctgtgtag gcttagtatt
    61921 tcaatagact tcctgcaaaa ctagaatcct agttcatgat tgataatacc agcaatcaaa
    61981 ttcattcgta atccgaagcg tttacgatga tttcgatagg ttgttgaaaa cattttaaac
    62041 gtttttactt tggcaaagat gttctcaacc ttgcttctct ccttagatag cgcatggtta
    62101 caggctttat cttcagctgt tagcggcttg agtttgctgg atttacgtgg agtttgtgct
    62161 tgaggatata tcttcatgag ccttcatagc gtgaaatttc tttttaccag aatcattcgc
    62221 taattctttt tttagggcga ttgattttta cttccgtcgc atcaatcatt accgtgtcct
    62281 cagaactgag aggagttctt gaaatcgtaa caccactttg aacaagagtt acttcaaccc
    62341 attggctccg acggattaag ttgctttcgt gaataccaaa atcagccgca atttgttcat
    62401 aagttcgata ttctcgcaca tattgaagag tggccataag aaggtcttct aggcttaatt
    62461 taggttttcg tccacctttt gcgtgtttaa gttgataagc tgtttttaat acagctaaca
    62521 tctctttaaa agtcgtgcgc tgaacaccaa caagacgctt aaatcgtgta tcagttaatt
    62581 gtttacttgc ttcataattt cgcagggagt ctattgactc tttggtaggt gtcaatgttt
    62641 ttttcatcta tcccgagaat tattttcccg ccatttgtat ttgcaaatgc tgagtaggtt
    62701 tcccagaaag actctggaag attgttttta gcttttttgt attctaaatc aaccccttca
    62761 aattttaagt ccatattttt cctttgcatc tgttttttgt ggttctggta tttgttcaag
    62821 ttgagtgata atatagcgaa ttgaatttcg agagttttta ctcagttaat tttccttgac
    62881 ttaaaattta aaaatgatat actgtgttta tggagagatg acaatttata aaatgtacta
    62941 ctctattcta ctagataatg attgaataaa actttttata acaacggcta gcaaagttat
    63001 aattttatat ctattagaaa ataaatatgt aaggaaattt aaatgaaaaa aactacaata
    63061 ttatcattaa ctacagctgc ggttatttta gcagcatatg tccctaatga accaatccta
    63121 gcagatactc ctagttcgga agtaatcaaa gagactaaag ttggaagtat tattcaacaa
    63181 aataatatca aatataaggt tctaactgta gaaggtaaca taggaactgt tcaagtgggt
    63241 aatggagtta ctcctgtaga gtttgaagct ggtcaagatg gaaaaccatt cacgattcct
    63301 acaaaaatca cagtaggtga taaagtattt accgttactg aagtagctag tcaagctttt
    63361 agttattatc cagatgaaac aggtagaatt gtctactatc ctagctctat tactatccca
    63421 tcaagcataa aaaaaataca aaaaaaaggc ttccatggaa gtaaagctaa aactattatt
    63481 tttgacaaag gcagtcagct ggagaaaatt gaagatagag cttttgattt ttctgaatta
    63541 gaagagattg aattgcctgc atctctagaa tatattggaa caagtgcatt ttcttttagt
    63601 caaaaattga aaaagctaac cttttcctca agttcaaaat tagaattaat atcacatgag
    63661 gcttttgcta atttatcaaa tttagagaaa ctaacattac caaaatcggt taaaacatta
    63721 ggaagtaatc tatttagact cactactagc ttaaaacatg ttgatgttga agaaggaaat
    63781 gaatcgtttg cctcagttga tggtgttttg ttttcaaaag ataaaactca attaatttat
    63841 tatccaagtc aaaaaaatga cgaaagttat aaaacgccta aggagacaaa agaacttgca
    63901 tcatattcgt ttaataaaaa ttcttacttg aaaaaactcg aattgaatga aggtttagaa
    63961 aaaatcggta cttttgcatt tgcggatgcg attaaacttg aagaaattag cttaccaaat
    64021 agtttagaaa ctattgaacg tttagccttt tacggtaatt tagaattaaa agaacttata
    64081 ttaccagata atgttaaaaa ttttggtaaa cacgttatga acggtttacc aaaattaaaa
    64141 agtttaacaa ttggtaataa tatcaactca ttgccgtcct tcttcctaag tggcgtctta
    64201 gattcattaa aggaaattca tattaagaat aaaagtacag agttttctgt gaaaaaagat
    64261 acatttgcaa ttcctgaaac tgttaagttc tatgtaacat cagaacatat aaaagatgtt
    64321 cttaaatcaa atttatctac tagtaatgat atcattgttg aaaaagtaga taatataaaa
    64381 caagaaactg atgtagctaa acctaaaaag aattctaatc agggagtagt tggttgggtt
    64441 aaagacaaag gtttatggta ttacttaaac gaatcaggtt ctatggctac tggttgggtt
    64501 aaagacaaag gtttatggta ttacttaaac gaatcaggtt c
//
LOCUS       DAVLGK010000006        57294 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLGK010000006 DAVLGK010000000
VERSION     DAVLGK010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57294
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.006"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..99)
                     /gene="rrf"
                     /locus_tag="VXE01_000426"
     rRNA            complement(<1..99)
                     /gene="rrf"
                     /locus_tag="VXE01_000426"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(176..3077)
                     /locus_tag="VXE01_000427"
     rRNA            complement(176..3077)
                     /locus_tag="VXE01_000427"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            complement(3202..3274)
                     /locus_tag="VXE01_000428"
     tRNA            complement(3202..3274)
                     /locus_tag="VXE01_000428"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3239..3241),aa:Ala,seq:tgc)
     gene            complement(3326..4871)
                     /locus_tag="VXE01_000429"
     rRNA            complement(3326..4871)
                     /locus_tag="VXE01_000429"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(5124..5195)
                     /locus_tag="VXE01_000430"
     tRNA            complement(5124..5195)
                     /locus_tag="VXE01_000430"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5160..5162),aa:Glu,seq:ttc)
     gene            complement(5289..5768)
                     /locus_tag="VXE01_000431"
     CDS             complement(5289..5768)
                     /locus_tag="VXE01_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0749409.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            complement(5890..7848)
                     /gene="ftsH"
                     /locus_tag="VXE01_000432"
     CDS             complement(5890..7848)
                     /gene="ftsH"
                     /locus_tag="VXE01_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV0749410.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(7864..8406)
                     /gene="hpt"
                     /locus_tag="VXE01_000433"
     CDS             complement(7864..8406)
                     /gene="hpt"
                     /locus_tag="VXE01_000433"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV0749411.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(8410..9687)
                     /gene="tilS"
                     /locus_tag="VXE01_000434"
     CDS             complement(8410..9687)
                     /gene="tilS"
                     /locus_tag="VXE01_000434"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV0749412.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(9684..10952)
                     /locus_tag="VXE01_000435"
     CDS             complement(9684..10952)
                     /locus_tag="VXE01_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV0749413.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGELTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(11072..11440)
                     /locus_tag="VXE01_000436"
     CDS             complement(11072..11440)
                     /locus_tag="VXE01_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV0749414.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(11433..11699)
                     /locus_tag="VXE01_000437"
     CDS             complement(11433..11699)
                     /locus_tag="VXE01_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0749415.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(11757..15266)
                     /gene="mfd"
                     /locus_tag="VXE01_000438"
     CDS             complement(11757..15266)
                     /gene="mfd"
                     /locus_tag="VXE01_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV0749416.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(15267..15836)
                     /locus_tag="VXE01_000439"
     CDS             complement(15267..15836)
                     /locus_tag="VXE01_000439"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV0749417.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(15907..17022)
                     /gene="ychF"
                     /locus_tag="VXE01_000440"
     CDS             complement(15907..17022)
                     /gene="ychF"
                     /locus_tag="VXE01_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV0749418.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(17106..17300)
                     /locus_tag="VXE01_000441"
     CDS             complement(17106..17300)
                     /locus_tag="VXE01_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV0749419.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(17365..18501)
                     /gene="dnaN"
                     /locus_tag="VXE01_000442"
     CDS             complement(17365..18501)
                     /gene="dnaN"
                     /locus_tag="VXE01_000442"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV0749420.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(18660..20021)
                     /gene="dnaA"
                     /locus_tag="VXE01_000443"
     CDS             complement(18660..20021)
                     /gene="dnaA"
                     /locus_tag="VXE01_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV0749421.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(20234..20992)
                     /locus_tag="VXE01_000444"
     CDS             complement(20234..20992)
                     /locus_tag="VXE01_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV0749422.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(21050..22231)
                     /locus_tag="VXE01_000445"
     CDS             complement(21050..22231)
                     /locus_tag="VXE01_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0749423.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            22414..22893
                     /gene="rlmH"
                     /locus_tag="VXE01_000446"
     CDS             22414..22893
                     /gene="rlmH"
                     /locus_tag="VXE01_000446"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV0749424.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            22937..23010
                     /locus_tag="VXE01_000447"
     tRNA            22937..23010
                     /locus_tag="VXE01_000447"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22971..22973,aa:Arg,seq:tct)
     gene            23175..23300
                     /gene="comC"
                     /locus_tag="VXE01_000448"
     CDS             23175..23300
                     /gene="comC"
                     /locus_tag="VXE01_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV0749425.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            23321..24646
                     /locus_tag="VXE01_000449"
     CDS             23321..24646
                     /locus_tag="VXE01_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0749426.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            24643..25395
                     /locus_tag="VXE01_000450"
     CDS             24643..25395
                     /locus_tag="VXE01_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0749427.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            25447..25518
                     /locus_tag="VXE01_000451"
     tRNA            25447..25518
                     /locus_tag="VXE01_000451"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25480..25482,aa:Glu,seq:ttc)
     gene            25524..25597
                     /locus_tag="VXE01_000452"
     tRNA            25524..25597
                     /locus_tag="VXE01_000452"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25558..25560,aa:Asn,seq:gtt)
     gene            complement(25638..26180)
                     /locus_tag="VXE01_000453"
     CDS             complement(25638..26180)
                     /locus_tag="VXE01_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV0749428.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            26359..27921
                     /locus_tag="VXE01_000454"
                     /pseudo
     CDS             26359..27921
                     /locus_tag="VXE01_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
     gene            complement(27951..30503)
                     /locus_tag="VXE01_000455"
     CDS             complement(27951..30503)
                     /locus_tag="VXE01_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV0749429.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTKAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(30565..32187)
                     /locus_tag="VXE01_000456"
     CDS             complement(30565..32187)
                     /locus_tag="VXE01_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0749430.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            32393..33418
                     /gene="trpS"
                     /locus_tag="VXE01_000457"
     CDS             32393..33418
                     /gene="trpS"
                     /locus_tag="VXE01_000457"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV0749431.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            33570..35048
                     /gene="guaB"
                     /locus_tag="VXE01_000458"
     CDS             33570..35048
                     /gene="guaB"
                     /locus_tag="VXE01_000458"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV0749432.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(35099..36196)
                     /gene="recF"
                     /locus_tag="VXE01_000459"
     CDS             complement(35099..36196)
                     /gene="recF"
                     /locus_tag="VXE01_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV0749433.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(36199..36567)
                     /gene="yaaA"
                     /locus_tag="VXE01_000460"
     CDS             complement(36199..36567)
                     /gene="yaaA"
                     /locus_tag="VXE01_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV0749434.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            36726..37976
                     /locus_tag="VXE01_000461"
     CDS             36726..37976
                     /locus_tag="VXE01_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0749435.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            37973..39256
                     /locus_tag="VXE01_000462"
     CDS             37973..39256
                     /locus_tag="VXE01_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0749436.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            39298..40119
                     /locus_tag="VXE01_000463"
     CDS             39298..40119
                     /locus_tag="VXE01_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0749437.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            40130..40675
                     /gene="pgsA"
                     /locus_tag="VXE01_000464"
     CDS             40130..40675
                     /gene="pgsA"
                     /locus_tag="VXE01_000464"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV0749438.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            40672..41499
                     /locus_tag="VXE01_000465"
     CDS             40672..41499
                     /locus_tag="VXE01_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0749439.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            41484..42323
                     /locus_tag="VXE01_000466"
     CDS             41484..42323
                     /locus_tag="VXE01_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0749440.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPVKIEEFKES
                     LNG"
     gene            42316..43110
                     /locus_tag="VXE01_000467"
     CDS             42316..43110
                     /locus_tag="VXE01_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0749441.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            43169..43987
                     /gene="mreC"
                     /locus_tag="VXE01_000468"
     CDS             43169..43987
                     /gene="mreC"
                     /locus_tag="VXE01_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV0749442.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            43987..44481
                     /gene="mreD"
                     /locus_tag="VXE01_000469"
     CDS             43987..44481
                     /gene="mreD"
                     /locus_tag="VXE01_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV0749443.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            44575..45753
                     /locus_tag="VXE01_000470"
     CDS             44575..45753
                     /locus_tag="VXE01_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV0749444.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            45977..46756
                     /gene="rpsB"
                     /locus_tag="VXE01_000471"
     CDS             45977..46756
                     /gene="rpsB"
                     /locus_tag="VXE01_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV0749445.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNK"
     gene            46822..47862
                     /locus_tag="VXE01_000472"
     CDS             46822..47862
                     /locus_tag="VXE01_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV0749446.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            complement(47983..48909)
                     /gene="cysK"
                     /locus_tag="VXE01_000473"
     CDS             complement(47983..48909)
                     /gene="cysK"
                     /locus_tag="VXE01_000473"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV0749447.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVYAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEFEV"
     gene            complement(49194..49829)
                     /locus_tag="VXE01_000474"
     CDS             complement(49194..49829)
                     /locus_tag="VXE01_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV0749448.1"
                     /translation="MEFRIIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            49885..51183
                     /locus_tag="VXE01_000475"
     CDS             49885..51183
                     /locus_tag="VXE01_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0749449.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            51180..51842
                     /locus_tag="VXE01_000476"
     CDS             51180..51842
                     /locus_tag="VXE01_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV0749450.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNNDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            51922..52470
                     /gene="raiA"
                     /locus_tag="VXE01_000477"
     CDS             51922..52470
                     /gene="raiA"
                     /locus_tag="VXE01_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV0749451.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            52606..54579
                     /locus_tag="VXE01_000478"
     CDS             52606..54579
                     /locus_tag="VXE01_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV0749452.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNIQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            54576..55028
                     /gene="rplI"
                     /locus_tag="VXE01_000479"
     CDS             54576..55028
                     /gene="rplI"
                     /locus_tag="VXE01_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV0749453.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            55072..56424
                     /gene="dnaB"
                     /locus_tag="VXE01_000480"
     CDS             55072..56424
                     /gene="dnaB"
                     /locus_tag="VXE01_000480"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV0749454.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            56426..56692
                     /locus_tag="VXE01_000481"
     CDS             56426..56692
                     /locus_tag="VXE01_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749455.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            56781..>57294
                     /gene="cbpD"
                     /locus_tag="VXE01_000482"
     CDS             56781..>57294
                     /gene="cbpD"
                     /locus_tag="VXE01_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0749456.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIH"
BASE COUNT        17419 a        10404 c        10985 g        18486 t
ORIGIN      
        1 tctcacaggg ggcaaccccc aactacttcc ggcgttctag ggcttaactt ctgtgttcgg
       61 catgggtaca ggtgtatctc ctaggctatc gtcacttaac tctgagtaat acctactcaa
      121 aattgaatat ctattcaatt taagaaaacc gttcgctttc atattctcag ttactttgga
      181 taagtcctcg agctattagt attagtccgc tacatgtgtc gccacacttc cacttctaac
      241 ctatctacct gatcatctct cagggctctt actgatatat aatcatggga aatctcatct
      301 tgaggtgggt ttcacactta gatgctttca gcgtttatcc cttccctaca tagctaccca
      361 gcgatgcctt tggcaagaca actggtacac cagcggtaag tccactctgg tcctctcgta
      421 ctaggagcag atcctctcaa atttcctacg cccgcgacgg atagggaccg aactgtctca
      481 cgacgttctg aacccagctc gcgtgccgct ttaatgggcg aacagcccaa cccttgggac
      541 cgactacagc cccaggatgc gacgagccga catcgaggtg ccaaacctcc ccgtcgatgt
      601 gaactcttgg gggagataag cctgttatcc ccagggtagc ttttatccgt tgagcgatgg
      661 cccttccata cggaaccacc ggatcactaa gcccgacttt cgtccctgct cgagttgtag
      721 ctctcgcagt caagctccct tataccttta cactctgcga atgatttcca accattctga
      781 gggaaccttt gggcgcctcc gttacctttt aggaggcgac cgccccagtc aaactgcccg
      841 tcagacactg tctccgatag ggatcaccta tctgggttag agtggccata acacaagggt
      901 agtatcccaa cagcgtctcc ttcgaaactg gcgtcccgat ctcttagact cctacctatc
      961 ctgtacatgt ggtacagaca ctcaatatca aactgcagta aagctccatg gggtctttcc
     1021 gtcctgtcgc gggtaacctg catcttcaca ggtactaaaa tttcaccgag tctctcgttg
     1081 agacagtgcc caaatcatta cgcctttcgt gcgggtcgga acttacccga caaggaattt
     1141 cgctacctta ggaccgttat agttacggcc gccgtttact ggggcttcaa ttcatacctt
     1201 cgcttacgct aagcactcct cttaaccttc cagcaccggg caggcgtcac cccctataca
     1261 tcatcttacg atttagcaga gagctgtgtt tttgataaac agttgcttgg gcctattcac
     1321 tgcggctgac ttaaagtcag caccccttct cccgaagtta cggggtcatt ttgccgagtt
     1381 ccttaacgag agttctctcg ctcacctgag gctactcgcc tcgactacct gtgtcggttt
     1441 gcggtacggg tagagtatgt ttaaacgcta gaagcttttc ttggcagtgt gacgtcacta
     1501 acttcgctac taaacttcgc tccccatcac agctcaatgt tatagaatta agcatttgac
     1561 tcaattcaca cctcactgct tagacagact cttccaatcg tctgctttag ttagcctact
     1621 gcgtccctcc atcactacat actctagtac aggaatatca acctgttgtc catcggatac
     1681 acctttcggt ctctccttag gtcccgacta acccagggcg gacgagcctt cccctggaaa
     1741 ccttagtctt acggtggaca ggattctcac ctgtctttcg ctactcatac cggcattctc
     1801 acttctatgc gttccagcac tcctcacggt ataccttcat cacacataga acgctctcct
     1861 accataccta taaaggtatc cacagcttcg gtaaattgtt ttagccccgg tacattttcg
     1921 gcgcagggtc actcgactag tgagctatta cgcactcttt gaatgaatag ctgcttctaa
     1981 gctaacatcc tagttgtctg tgcaacccca catccttttc cacttaacaa ttattttggg
     2041 accttagctg gtggtctggg ctgtttccct ttcgactacg gatcttagca ctcgcagtct
     2101 gactgccgac cataattcat tggcattcgg agtttatctg agattggtaa tccgggatgg
     2161 acccctcacc caaacagtgc tctacctcca agaatctcta atgtcgacgc tagccctaaa
     2221 gctatttcgg agagaaccag ctatctccaa gttcgtttgg aatttctccg ctacccacaa
     2281 gtcatccaag cacttttcaa cgtgccctgg ttcggtcctc cagtgcgtct taccgcacct
     2341 tcaacctgct catgggtagg tcacatggtt tcgggtctac gtcatgatac taaggcgccc
     2401 tattcagact cggtttccct acggctccgt ctcttcaact taacctcgca tcataacgta
     2461 actcgccggt tcattctaca aaaggcacgc tctcacccat taacgggctc gaacttgttg
     2521 taggcacacg gtttcaggtt ctatttcact cccctcccgg ggtgcttttc acctttccct
     2581 cacggtactg gttcactatc ggtcactagg gagtatttag ggttgggaaa tggtcctccc
     2641 agattccgac gggatttcac gtgtcccgcc gtactcagga tactgctagg tacaaagact
     2701 attttaaata cgaggctatt actctctttg gctgatcttc ccaaatcatt cttctataat
     2761 ctttgagtcc acattgcagt cctacaaccc cgaagagtaa actcttcggt ttgcccttct
     2821 gccgtttcgc tcgccgctac taaggcaatc gcttttgctt tctcttcctg cagctactta
     2881 gatgtttcag ttcactgcgt cttcctcctc acatccttaa cagatgtggg taacaggtat
     2941 tacctgttgg gttcccccat tcggaaatcc ctggatcatc gcttacttac agctacccaa
     3001 ggcatatcgt cgtttgtcac gtccttcgtc ggctcctagt gccaaggcat ccaccgtgcg
     3061 cccttattaa cttaacctta ttttctgacc tttcagtcat aaactcttat taatactaca
     3121 gcgttttcgg tttattttct tgttactatt tgatatagat attcaatttt caatgtgcat
     3181 tacttggtga tctctcacca atggagccta gcgggatcga accgctgacc tcctgcgtgc
     3241 aaagcaggcg ctctcccagc tgagctaagg ccccacaaga cctctcaaga ctaaacaaga
     3301 ccaatgcgca gttccttatc cttagaaagg aggtgatcca gccgcacctt ccgatacggc
     3361 taccttgtta cgacttcacc ccaatcatct atcccacctt aggcggctgg ctccttacgg
     3421 ttacctcacc gacttcgggt gttacaaact ctcgtggtgt gacgggcggt gtgtacaagg
     3481 cccgggaacg tattcaccgc ggcgtgctga tccgcgatta ctagcgattc cgacttcatg
     3541 taggcgagtt gcagcctaca atccgaactg agactggctt taagagatta gcttgccgtc
     3601 atcggcttgc gactcgttgt accagccatt gtagcacgtg tgtagcccag gtcataaggg
     3661 gcatgatgat ttgacgtcat ccccaccttc ctccggttta ttaccggcag tctcgctaga
     3721 gtgcccaact aaatgatggc aactaacaat aggggttgcg ctcgttgcgg gacttaaccc
     3781 aacatctcac gacacgagct gacgacaacc atgcaccacc tgtcacctct gtcccgaagg
     3841 aaaactctat ctctagagcg gtcagaggga tgtcaagacc tggtaaggtt cttcgcgttg
     3901 cttcgaatta aaccacatgc tccaccgctt gtgcgggccc ccgtcaattc ctttgagttt
     3961 caaccttgcg gtcgtactcc ccaggcggag tgcttaatgc gttagctacg gcactaaacc
     4021 ccggaaaggg tctaacacct agcactcatc gtttacagcg tggactacca gggtatctaa
     4081 tcctgtttgc tccccacgct ttcgagcctc agcgtcagtt acaagccaga gagccgcttt
     4141 cgccaccggt gttcctccat atatctacgc atttcaccgc tacacatgga attccactct
     4201 cccctcttgc actcaagtta aacagtttcc aaagcctact atggttaagc cacagccttt
     4261 aacttcagac ttatctaacc gcctgcgctc gctttacgcc caataaatcc ggacaacgct
     4321 cgggacctac gtattaccgc ggctgctggc acgtagttag ccgtcccttt ctggtaagat
     4381 accgtcacag tgtgaacttt ccactctcac actcgttctt ctcttacaac agagctttac
     4441 gatccgaaaa ccttcttcac tcacgcggcg ttgctcggtc agacttccgt ccattgccga
     4501 agattcccta ctgctgcctc ccgtaggagt ctgggccgtg tctcagtccc agtgtggccg
     4561 atcaccctct caggtcggct atgtatcgtc gccttggtga gcccttaccc caccaactag
     4621 ctaatacaac gcaggtccat ctggtagtga tgcaagtgca ccttttaagc aaatgtcatg
     4681 caacatctac tcttatgcgg tattagctat cgtttccaat agttatcccc cgctaccagg
     4741 caggttacct acgcgttact cacccgttcg caactcatcc agagaagcaa gctcctcctt
     4801 cagcgttcta cttgcatgta ttaggcacgc cgccagcgtt cgtcctgagc caggatcaaa
     4861 ctctcattaa aagtttgagt tctcactcat ttctgtcact gacagattta ttgttttttt
     4921 cattgttcag tactacaact tatgttgtag cgccctgcac attggttcgt cttgttcagt
     4981 tttcaaaggt ctttgtcact tgcttctctc aagcgacaac tatattagta tatcacagcc
     5041 actttcactt gtcaacactt ttttgaagat ttttaagttt ttttaaactt tttttcatca
     5101 agtggtcctg acgcaacata ccatagtccg tacgggattc gaacccgtgt taccgccgtg
     5161 aaaaggcggt gtcttaaccc cttgaccaac ggacctgagt tgttattttc aactcttact
     5221 attatacagt cttttcaaac tttgtcaact actttttcta atttttttca ttttttttgc
     5281 atgacttact agtgggtacg gatagtaaac tccttaaaca caatgcgtaa gtctcttaat
     5341 actctttgac gccctcgaaa tcgttcattg cttaagacgc gttctagttc ttcttgtttc
     5401 tctttacttt gtttgtttct ataatctctt agtgtttcat gaaagagata ataatcatct
     5461 agccagagac ctccctcact tatacgatga ctgatctcac ccacttcttc atagggttct
     5521 ttatcgtatc tacgcttctg actttcctgc ttacggatat agtctaaaat tcgatttcga
     5581 aacttggttt tgaaatattt ccttaaacgt ggaatatcgt ctgccagtcc ttcttctcta
     5641 ctaatcaatt catgtaagca gagcatgcct tcttggtccc aatccgacaa ttcccataaa
     5701 tgaaggtaat attcatttct acacttatac acagtccctt ggacttcttc atacaattct
     5761 ttaatcataa ttttcccctt tctagataca gtctaacaga ttagaaaaca catttgttcc
     5821 attttatcca ttctgttccc tttagctcct aaactgtaca aaaaagagag gctccagcct
     5881 ctctcagggt tatttttcgt cattcatttt tgactttact tcatcatagg atagtgcatg
     5941 agattcctct tctactgctt caggcatctt tcctgtttcg taaagagctt taatttgtgt
     6001 actatccaat gtttcgtatt tcaataatgc ttctgcaatt aacttgtgag tttcacgatt
     6061 tgactgaata atttcagcag ctttatttcg tgcctcattt aataatgaac gaacctcttc
     6121 atcaatttca taagctgttt gttctgaaat tgatttttga ggactctgtg caccaagcat
     6181 agcatggttt ccttcatatt gtactgggcc aagtttttca ctcataccgt actctgtaac
     6241 cattgcacgt gccatttgtg tcgcttgttc aaagtcgttt gaagctcctg tagtttggac
     6301 attaaagata atttcttcag ctacacgtcc acccattaag ccagccaatt gctctttcat
     6361 atcttcttta gatagaagca tttgatcctc tttaggaagt gcaatcatgt atccgcctgc
     6421 acggccgcgt ggtacaattg taaccttatg gacaacgcga gcattcgaca agactagacc
     6481 aacaatggta tgtcctgcct catggtaagc aaccaattct cgttcttttt gtgaaactgt
     6541 cttatctttc ttagaaggtc cagcaataac tctatcttct gcttcatcaa tatctgaagc
     6601 atcaattatc gatttattgc gacgagcagc aactaaagct gcttcattca agacattctc
     6661 taaatcagca ccaacaaagc ctggagtttg ttgagccact aatttcaaat caacatcttc
     6721 tgctaaaggc ttgttcttag cgtgaacttt caagattgct tcacgacctt taacatcagg
     6781 acggccaacc aatacttttc tatcaaaacg tcctggacgc aaaagggcag gatcaagtac
     6841 atctgaacgg tttgtcgcag cgatgacgat aatcccttca tttccctcaa aaccatccat
     6901 ctcaatcaaa agttggttca aggtttgttc acgttcgtca ttacctccgc cgagaccgac
     6961 tccacgttga cgtccaacag catcaatttc atcgataaag atgatagctg gtgctgcttt
     7021 tttggcatcc tcaaaaagag agcgaacacg actagctcca actccgacaa acatttctac
     7081 aaagtcagaa cctgagatac taaagaatgg aacacctgct tctccagcga ctgccttagc
     7141 aagcaaagtc ttacctgtcc ccggaggtcc ctccaaaaga acacctgctg gaatacgggc
     7201 tccaagtttt gtgaatcgtt ttggatcttt taagaactca acaacttcaa ctagttcttg
     7261 tttttcttcc tcagctccag caacatctga aaatcttact ttaatatctt ctttatttgc
     7321 tgctttagcc ttactacgtc caaaactcat tggattacgg ccattgcctc ctcccatatt
     7381 tcccatcata gagaatagga agaagaatag aattccaaat ggcacaatgg atacgagtag
     7441 attaatccat ataccacttg aactttcatg cttaacagtt acttctgctt tatggtcagt
     7501 agcaagtttt tgcaattctg atacggtagt atctgcagga agaatagtgc tggtaaattt
     7561 ctctacctta gtaacagatg gcgtgaaaaa ctgaatacct gttccttctt tacttgtttt
     7621 aggattttta tagacaccag aaacttcgat aacactacca tttggttggt aagttaattc
     7681 ttttacatta ccatcggtaa tttcttgtac caactcagta tagttgattt gctgacttcc
     7741 tcctgagtta ttcccagaat agaaatactg gaatcctgtc acaaggaaaa agataaataa
     7801 taaccataga aaaggatttt taattaaacc attattttgt tttttcatta aagattattc
     7861 tttctaattt gaatacactt cctctttcaa tactccaata taaggaagat tacgataatt
     7921 ttctttgtag tctaaaccat aacctactac aaactcattt gggatagtaa agcaggtata
     7981 gtctgcctca atttctacaa cacgtccttc tggtttatcc aacaaggttg caattttaac
     8041 agaagctgct tctcttgctt taaacatatc tcgcaaattc ttcaaagttt gacctgtatc
     8101 aatgatatct tctacaaata gaacatgtct tcctttgata tcttgagtca catcttgttt
     8161 aatattgata acaccactac ttgctgttcc accatggtag ctagaaacca tcatgaagtc
     8221 catttcaata tgtgtatcaa tatgtttgac caattcagcc ataaaaggaa tagatccttt
     8281 taaaatccca actaagattg gattttttcc tgcataatct ttagttaatt gagcacctag
     8341 ttttttagct gcttctgtaa tttcatcgtg tgaaacgagg acttttttaa tatcgttttc
     8401 taacattttt tacctatcta ttttttctat ataaagtaca gtgttcatta tatcattttt
     8461 cgttttttta ctcaaattat tggtcgcaat tcccaaaatt gagacaattt caccaaattg
     8521 ctcaataata agagcagagt ttctcttttc catagggatt ttcaaatcaa taaataaacg
     8581 tctgagtttt tttctatgcc cattttgaat caaaacatct cctgtttttc gatgacgaat
     8641 gtgtatggat gtttcacgtg aaacaggtat ttgttgaatt gattcacctt ctaatggaag
     8701 tccaaaggaa aataaatatc cttgataagc tacctgattt tgatagtgta acacaagttc
     8761 atcttccttt tcatcagcct gcggactgat tttacaaatc tgaaactgtt ggtactcttt
     8821 tatcaattca tagccatttt taatcggatg acgatactgg cttttagatt ttaaaatctg
     8881 ctgaacttca gcaaactgag cttttgtaag attcaaatct ggaaaacgat tcagataagt
     8941 ttgaagtaaa actctttgtg tagactcaga gtaagaaaat aactgctgta aatcttccac
     9001 attaatattg ttagataatt cagctattgc caaatcataa tctaaaattt cattgccaat
     9061 gcctaagatt gcatccctaa atcgaggatt ttctttttcc aattctggta agtaagagtt
     9121 tcgaatacga tttcgaaaat aatgattctc ctgatttgat gtatcttcaa agtgaaaaat
     9181 tgatggaaag tcttttttct gaaaatgcaa gaagggacga atgatttcta tctctccgac
     9241 tacttgcttc tccttaattc ctgatagata gcgcaagcga gttcctcgaa tcaagcgcat
     9301 caaaatcgtt tccacctgat catcagcatg gtgggcagtg actaaagctg tcgcacctgt
     9361 ctttttcata acctcttgaa aaaaatcata acgaaaattt cgtgcacgcg cttctgaaaa
     9421 ttctcctgaa aaattgctga tataaatagg aagctctgct tcagcagcca acttccttaa
     9481 ttccttttct tcccaatctg attcaattct ctgcttatga ttcacatgag ccagaatcaa
     9541 ttcaatctct aactcttttt gataagtaga caatacctta aatagaaaca tagaatctaa
     9601 tccaccagaa agagctagaa ccgccttagc atgctttttg aaatatccct tcttgagaaa
     9661 atgatttaaa aaatctggtt ccctcatttt agaacctcat aaacatcctt ggctatctta
     9721 gaaatcgtat cataatcaga attcttagtg aaaatagaaa gaataaatgg agaatctgca
     9781 tagacaacac ccgtatcatg cttaaattca tccgcatctc caattttatg agctacttta
     9841 acagaaacac ctttggcaat tcgctgacta tcaaaatctg ttttagtcaa agactctagc
     9901 acaaatccat tttgattata aatagcttcc ataaacttcc cggccatctt agaagaaatc
     9961 aatttttctt ttggatccca atcatctccc ataatggcag acattttgga tttgaatgtg
    10021 gcatcagatt ggtttgaaat gtaatatccc aatagattat gagctacatt atcagattct
    10081 tttgatactt tcgtaattaa atcctttaaa gaatattctt tattatcttc ttttttagga
    10141 agactaccac ttccctctgg tttataagaa cctggaaaat cattgactgc agatacgtat
    10201 tttacagtcg tatctaactg ataaagaccc tcatttattt tttcttgcgt ataatagaga
    10261 taggagagtt tcaaaacgct ggctgcatac atcttttcat cttgattgat accagcttct
    10321 tttccagtag tcagttgctt aacataaata gagaaagaat ctttctgata tttttcagat
    10381 aacatttctt gaactttact catccgatta tcttcttcag aagttgattc tttagctacc
    10441 catccagcct gatcaatatg tagaaattct cttccttcta caaacatggt cttgtcgatt
    10501 gatacttgcg aataagctga taaggatgat ttcacttctt ttaaatcata aggactattg
    10561 tacagtttaa agtcagattc taaccatact ttttttattg ttggagttac ctctgattga
    10621 tcatataaaa atcgtttgtc cgcagctata aattgatgat ttgatagctt aaatactgga
    10681 atcccttgtt tatttaagcg ccactcggtt atttgaaaac ttgttttggg agtcaattcc
    10741 ccagattcca ctactaaatc ttcattcgca taaacaggaa cctctccata aaccatggga
    10801 gaacttaatt tttctctaaa ataaatacca aagtcagatt gtgaaaggta ataaatttct
    10861 ttcgaagtat agacgacttc tttttctgtg ctaacgactt ttgaaatggt caaaaaactt
    10921 ggtagcaaca aaataattaa gaatttacgc attcttcctt tccttttctt cttgtaaacg
    10981 caataattga tttttatcag ccaattcttc caacttttca tctgacaaac ccaaaaattg
    11041 ctctattacg tctaataaat tttccatttt atcacctttg aagcaagtca ggaatcgtat
    11101 aaactttttc cctcgactta gaataatagt acttcgctcg tgtatattta gcagcataat
    11161 cttcatcttt caacttggta gcaaatgctg tctccttatc cttttcatca ctcaaagttt
    11221 gatactgagt ttgcaagtct gctaattgct gacgtctttg gagtaattgc tgataactct
    11281 gcgctaaatt aaaagttggc aagataaata atagcataat caaaatcaat acccctccca
    11341 taaaacgatt ccgtttttgt cgttctttca tcaggtagcg acgacgttgg tattcatttt
    11401 gaataaaaga attattcaat tgtacaatat ttttagacat tttcttctac ccgtgtttca
    11461 ctgataattt catacattcc tgctgcatct tctttttttg tactatcttt catctctagt
    11521 acttttacaa gcagcaactt attgccaaag cgaatttcaa cttggtcatt aactttcaag
    11581 tccgttgaac ttttggccaa gattccatta accttgattc tacctttatc tgctacttcc
    11641 tttgcgactg tacgacgctt gataattcgc gatactttta aatatttatc taatctcatc
    11701 cttattacct caatttatta ttgtaccatt tttatctatt ttatagaaga aaaatatcaa
    11761 atggaatttt cttccttaga ctcttttatc tctaataaac tttctccaaa aatcagcaga
    11821 ccttctaaaa tttcataatc tttcttattt tgaacatcaa atacaagctc cattaattcc
    11881 ttattctcag cgatgcctgc ttttaagttc gttacggata aagctttaaa ataatcttga
    11941 gctaaaaaca gtcgttgagt gactttttca aattgaattg taattttatt atcttttctt
    12001 tccacacgtt gaacaaagac cttgtccaag tatgatttga ccaaaccaat ctctaaaaga
    12061 taggctacta catctgggta ttctccaaaa cggtctatca actcctcttg taactcttca
    12121 taattgacac ggttgtcaat ttgacgaatt ttcttgtaaa tttcaatctt atgtcgttga
    12181 tcagaaatat aagtatcagg aagataggca tcaatttgca aaatcaactc agcattccct
    12241 ttggttcttg tgttagcgtt agcattaccg tttcgtttag caatagcttc ctctaataac
    12301 tgcgaataca attcaaaacc aacagaatca atgaaaccag actgggattt tcctaaaaga
    12361 tttcctgctc cacgaatcga aagatctcgc attgcaatct taaagccaga gcccaattct
    12421 gtaaatcctt taatcgcttc taatctcttt tcagagactt cactgattga tttttctgga
    12481 cgatacatga gataagcata agcaatacga ttactacgac cgactcttcc tcttaactga
    12541 tataaggttg acaagcccat atggtccgca ttttcaataa ataaagtatt agcatttgga
    12601 atgtccaccc ctgtctcaat aatagtagtc gtcaccaaga tatcgtattg tccctcaata
    12661 aagtctaata gagtattttc caactggact tcactcattc gaccatgaac atatccaatc
    12721 gaagcctccg gaatcaactc ctgtaattct gaaaccttct gaacaattgt gtcaactttg
    12781 ttgtaaagat aataaacttg acctccacgc tccatttcac gcaagacagc atcacgaatg
    12841 acactatcat tcttttccaa aacataggtc tgaacaggat agcgattagt cggcggagtt
    12901 tcaataacag ataaatctct gattcccagc atagacatat ggagggtacg agggattggc
    12961 gtagcggtca aggttaggac atccacttgt ttcttcagtt ctttcaaagt ttccttatgc
    13021 ttgacaccaa atcgctgttc ctcatcaata atcatcaagc ccaaatcagc aaacacaaca
    13081 tcttttgaca aaacacgatg tgttccaatc aaaatatcga cttgaccgtt tttcaatttt
    13141 tcaagtgttg cagtctgctc ttttttactt ctaaagcgac tcaacacatc aatattaact
    13201 gcaaaatttt ggaatcgttc cttaaaattc gtatagtgct gttgcgctaa aaccgtcgtc
    13261 ggaactagaa tgacaacctg tttgtgatca ttgactgctt taaaggctgc acgcatagca
    13321 acttcagtct ttccaaaacc aacatcccca actaaaagtc gatccattgg ctgagaagcc
    13381 tgcatatccc tcttgatttc ctcaatacta cgaagttgat catccgtttc aacataaggg
    13441 aaagcatcat caaaggcatc ttgatcatca tcatcagctg agaaagcaaa acccttcaac
    13501 tgactacgtt cagagtagag tttgattaaa tcatcagcta tatcctctac ctggttctta
    13561 accttttgct tggccttttt aaaatgaccg tcatttaatt tattgagttt tggagcttta
    13621 ccatcacttg aaatatattt ggacagtaga tgaatctgtt ccacgggaat agaaatttga
    13681 tcaccatttt ggtattggac actgacataa tcacgatgaa ttcccttgat ttcaatggtt
    13741 tcaattccta gatattgacc aatcccatgg atatgatgga caacatagtc ccctttttca
    13801 agttcattgt aatcttttaa tctctctgca tttgaaacat gttgtcttcg aaaacgacgc
    13861 tttaatttct tttgaaaaat ctcatgttca gttatcaata aaatcttttc atctacaaaa
    13921 tgaaaaccat gtctgagatt accctctatt aagtttacag attctttaca gatatttgtc
    13981 ttatctctag aatccaattt aatctgatat tcctctaaca tatcctccaa tgttttactt
    14041 cccattgaat tgctagactg cagaataatg gtgtaatcca tttttttata tcgttcaatt
    14101 tcttctttta gaaaagaaaa ctgattgaaa aattcctgca taggatattg attgaattga
    14161 taaattttgt caaatttgag atttcctaaa cccttttgaa gattagaaaa aaaggtcact
    14221 ggactttgtt ttttatagat ttgttcaata tcagaaaaat actgcatatc agaaaatgct
    14281 ttactattct gtaattcttc tgtaaagtac tgcgctaatt ctctttcaaa gacttcatac
    14341 tgattcatca atttttgata atcatcaaag aatattggag tatctttttc aatataatca
    14401 aagacagtcc atgtcttatc atagcacaaa gataaaaact tccgagagtc tgcatgactt
    14461 tgtttttggt gaaaacttga aagaatttct tctaggtatg atttcaaaat aggtgataaa
    14521 gtttttgaaa tttgtttttc taaagctgac tgtcctcgtt gataatcctt ttctctcaaa
    14581 agcatatcac tagctggaaa gatagtgagt tctgtcttat tttctttcga taattgtgtt
    14641 tctacttcaa atgacctgat accatcaatt tcatcaccaa aaaactcaat tcgacaaggt
    14701 tctaactggg atatttcaaa aatatctaaa atatctcctc gaagactaaa ttcgccctga
    14761 gtttgtactt gagtaacttt tcgatagcca ttttccttta actgatggat aaacgcgtgt
    14821 tgatcatatt cttcaccaac tgagattttt acaatactat ctttgaatgc attgggagac
    14881 ggtaaaatca atcgacttgc tgcgatatta caaactaaaa tccctttctt agatgaatca
    14941 gtcaaaaaac gcaaggcttc aacccgtgaa ataatttttt cctgtgaaga catcaaaaac
    15001 tccaccatag gagcatcatc taccaaaaat ggatagacga gttcctcacc caagatagat
    15061 ataagatcac taacaagtcc ttctgcttct ccataagttg acatcaataa cacaatccta
    15121 tcttcttttt ctaaactgct tgcaattgca agagccttag tagatgttga taaaccaagt
    15181 attagttgtc ttttcttatc tgttaaattt tgatgccatt ttttaatctg atcattttct
    15241 gagaataaat ctaataaggt caccatttat ccgttatacc tctgcattgt tttctcaaaa
    15301 tttttctctt gtaaatagta gtttacagaa tcgtcaactt tgtcaacaga ctgtaaaata
    15361 ccgatatact catccctgtc aaacttactc aaaacatgat gaacaactga cataccattt
    15421 ttaggtcttc caattccaat cttaacacgg ttaaagacct gagttcctat atgttgaata
    15481 atagacttga taccattatg accacctgct gagccttttg ctcttaaacg aattttccca
    15541 acttccatgt caagatcatc gtaaatgata agtaaatcgt caatatccaa accatagtaa
    15601 gttaataaag catgaactgc ttttccactt tcattcataa aggtcgttgg tttaaccaga
    15661 taaatttttt ctccatttag gaaaaaggat gctaggtcag cttgaaatat cttatcgtgt
    15721 gtaaaagtga cattctgttt cttcgctagt tgatcaatca acataaaacc aacattgtgt
    15781 tttgtttcaa aatatttatc ccctggattt cccaagccta caagtaattt ggtcatttat
    15841 ttttcctttc aaaagccaaa agggttggaa tttttttcca acctaattga caccatttat
    15901 taatttttag acattaaagc ggaattccat gatatcgcca tcttgaacga tatattcttt
    15961 tccttcttca cgcaagcgtc cagcttcttt tacggccttt tcagatccgt atttcactag
    16021 atcttcatat gacatggtta ctgcacgaat aaagcctttt tcaaagtctg agtggataat
    16081 accagctgct tgaggagcct tcataccacg tttgaaagtc caagcgcgaa cttctttttc
    16141 accagctgtg aagtaagttc ccaatccaag caagtggtaa gctgcacgcg tcaacttatc
    16201 tacacctgat tctgtcaaac caatggcttc aagaaactct tttttatctt catcatccaa
    16261 ttcagaaatt tcttcctcag cacgcgcaga aataacgact acttcagcat tttctgtcgc
    16321 tgcaaattca cgaatttgtt tgacatagtc gatagagtca ggttctgaaa ccacatcctc
    16381 gtccacatta gctacataaa gaactggttt agtcgtcaaa aggaaaagac ctttgacaac
    16441 cttttgttcc tcatctgtaa attcaatggt acgagctgat ttcccgtctt ctaggactgg
    16501 tttaatcttt tgaagaacat tgaattctgc tactgattct ttatcttttt gcgtacgtgc
    16561 catcttttct acacgcgcat atcgtttgtt cactgattct aagtcagcaa gaattaattc
    16621 cagattaatt gtatcaatat ctgcaagtgg atctacaaag gcgtcttcac gtccttgctc
    16681 gcgcatcaca ttttcatcat caaaagcacg aactacgtga acaatcgcat ctacttcacg
    16741 aatattggcc aagaatttat tccctagccc ttctcctttt gaagctcctt ttacaatccc
    16801 tgcaatatcc gtaaattcaa atgttgtggg aactgtcttt ttaggagtta tcatttcagt
    16861 tagtttttgt aggcgttcat ctggaacttc caccattcca acatttggat caatagtcgc
    16921 aaatgggtag tttgctgcct ctgctcctgc ttttgtaatt gcattaaata gtgttgattt
    16981 accaacgttt ggcaaaccaa cgatacctgc tgtcaaagcc atatttctca ttctccgttt
    17041 tcatttcaat ccctaatatt ataacacaaa aagggataaa gtgctaaccc tctaactaag
    17101 ggttctcagt caataatttt attcattttt cgctcaaaat catatcgccc catcatgaca
    17161 acatgctcac aattactgca ttttattttg atatctgctc ctacacgtgt aatttcccaa
    17221 cgattagcct ttttaccagt cgacttgatt gtacaagcgt gtgatttttt catctcaaca
    17281 aaatttccaa cttgatacat actactctcc ttttcttttt cgattatatc ataaaagagg
    17341 cgagccaggc tcaacctctt tcacttaatt tgtacgaact ggtgtaatga gctgcatgaa
    17401 gtcttcgtca gtatctgctg gcacaagagt aaatggacga acagctgaga taaagctaat
    17461 ggtcaccttt tcgctattta aagctttaag agaatcaatc aagtaagttg ggttgaaact
    17521 aatggtcaaa tcttcaccag taacctgatc agtatcgatt tcttcgttta ctttaccaac
    17581 ttctggagag tgaacatggg cgctaacaac cccatcctta atttcaagtt tcacagtacc
    17641 attttgagtc gcacttgata aaagacgggc acgctccatt gactggcgta agtttaccac
    17701 attaaaagta atagtagtgt taaagtctgt tggaatcaag cgatctgtat caggatagtt
    17761 tccttctagg agacgagtat agaagctaat attttcgctt ctaaagagga tttggttatt
    17821 ggcaaagaaa atctctacag tttcgatatc atctgtaaat accgctgaaa attcgcgtag
    17881 agaacggcta ggaattacga catcaaaatc atcactattt ttttcaagag tcaatttttt
    17941 ctggcttagg cgatgagagt ctgttgcaac tgtttttaac tctttgtgtt gactcaatac
    18001 gaagtggaca cctgttaaaa tcggacgact ctcttgtgta cttgcagcaa aggctgtttc
    18061 attaataatt ttcttgagta attttgtttc aagtattaaa ggagtgcttg ctgaaatttc
    18121 ttggattcgt ggatattgtt cgctatcttt tccttttagg gtaatttctg atttgccact
    18181 ggttaaaaca atttgatttt gttcaatttc tttaaaatca agagttacat caggtaaact
    18241 agatactaca ttgataaaga aagaagcttc aagaaggatc gaacctaaag aagtaattaa
    18301 caaaccagca tcttcatttt tttgagaaat aaaattttca attgaaattt gaccatttga
    18361 accaattaaa gtaatacctt cattggtcac gtcaattttt actgttgata aaataggaat
    18421 ggcattttta gaactaatag ctctcttagt agtatttaat gcttgtagaa ataaattttt
    18481 attaattgaa aaatgaatca tggattctcc tttatttatt tttagtatta gaaagataat
    18541 agtaataata gagtctgtga aatctgtgga aaacagcctt taaacaagtc atatcaagtt
    18601 ttttagcttg tttaaaaaat gtggataaaa aagataaaaa actaaaagtt atccacaaat
    18661 tatttgattt tctttttgat tgattcaatt tctaaacgta aattatcgtc ttgatcaatc
    18721 aaagatttta ttttggcatg ggcatgaatg actgtggtat gatcttttcc cccaaattcc
    18781 ttcccaattt ttggaagact attatctgtt agttctctag ataaatacat ggctacttga
    18841 cgggccaaaa caatattttg aaggcgtcta cttcccttca tttctttgat actaacacca
    18901 taaaagttac caacttcagt ttggatttta tcaattggga tgacgagcat ttggctaaca
    18961 tcttgtttgc gggctctaat ggcttctgca gcaatatcaa tagtgatatc cttgattttt
    19021 tttactctgg caattaaagt gatgtcgttg atggctccct caagatctcg aacatttgaa
    19081 tcaaattgcc cagctaggta ttctagagta tcactttgga aattgtagcc taaatgttcc
    19141 gttttacttt gtaaaatggc aatacgtgtt tcaaagtcag ggggtgtgat agtttgtgtc
    19201 aatccccaac taaaacgcgt gacaagcctc tcctcgagcc cttctagatg ttttggacta
    19261 cgatcactcg ttaggacaat ctgtttttgc ttgtcatgaa gggcgttaaa ggtattgaaa
    19321 aattcttcct gagttgcaac tttttttccg ctgagtgact ggatatcatc gattaacaaa
    19381 agatcaagac tacgataggt ctttttaaac ttttccattt ccccaagtct taggtgatca
    19441 agaaagtcat taataaagct ttcggcaggg atatatttaa cacgcgcatt aggaatattt
    19501 tttagaattt catttccaat agcgtttaat aagtgagtct taccaaggcc tggtcctcca
    19561 tagataaaaa gagggttata ggtcagagcc aaatcttcag agacagctaa agcggctgat
    19621 acagcccaaa catttccatc cccttgaata aagttatcaa aggtatactt ttcttttaat
    19681 cccgtatctg aataaggaat agatactaac tttggactat agttataaag agttaaattt
    19741 gtagcttctt caacttgtga gctagtcgta tcttgaggtt tggtgaaaat atagtgggga
    19801 gttatttcag cgtcataaat ttcaaaacca gctactacaa taatatcttt tagttgtttt
    19861 tcccagacca tttccatttc agagcgaggt agaaatatag tggcaacatt ttcctctacc
    19921 ttgatgagtt cagcttgaat agcatagaaa tcatacatgg atcgagtcag tctttcttgt
    19981 gcaaattcta atatacgatt ccaaaattgt ttttctttca atcctttctc ctcctttact
    20041 atttaaaagt ttaatactag agatatttta ccatagatag caagaatttt ccacaagctg
    20101 tgaaaaataa tccacaatgt taccaaactt tatccacagg ttggggataa aagaagaaat
    20161 tattgattta ttaagctttt tatcgaaaaa catagtggat aaccttgtga gataaaaaaa
    20221 taaaagaaca gccttatttc aggctgttga taattctact atattcttct tgatttgaaa
    20281 aagaaataat gatttttcca ctgtcttttt tagatagttt aatttctaca tctaatccga
    20341 gtagttttct taactgtttt tcttcatttt gtatgaaatg attagttttt tgctgtttct
    20401 tttgtttttt ctctgtcaga agagcttcta atttccttac agaaatatct tcttctataa
    20461 tccgttgaaa gaaatagtct tgttgttcct tatttaaccc aactagggaa cgcgcatggg
    20521 cttgtgatag tttgccattt tctacttctg aaagaatctg ttctggcaag gaaagtaaac
    20581 gaatggagtt gctgatatat ggacgagact tgcccatctt atctgcaatt tcagcatggg
    20641 tgaatccttt ctctacgaga gattcatagg cgcgtgcttc ttctattggg tttaaatttt
    20701 ctctctgtaa attttcaata atggactgga ccatcatctc ttggtctgaa atctgtttaa
    20761 caacagctgg gatagaccgt agaccagcta aaagtgaagc ccgatagcgt ctctctcctg
    20821 caaggatttc ataaccaata acaggagatt gacgaacaat aatcggttga atgaccccat
    20881 tttctttgat agactgtgct agttcatcta gtttttctct atcaaattct tttcggggtt
    20941 gatagggatt tttttgtata tctgtgatag aaatcatttc aaatttttcc atgattctac
    21001 actaacacat cttttctctt atgtaaagct ttctttacat agatgtcaat caagattcta
    21061 aatcacctga actcttgtta agtttgatag aggtagtttc ttctttcccg ttacgatagt
    21121 aggttatctt aatggtgtct ccgatagaat ggttgtaaag agcactttgt aagtctgttg
    21181 atgaagcaat ctctttgtca tctacttttg taattacatc gtatttttca aggtgaccat
    21241 tggcaggcat attactttgt accgaacgaa caactacacc agatgtaaca ttacttggaa
    21301 tattgagtct tctgatgtcg cttgtactca cattagataa attaaccatc tggattccca
    21361 aagctggacg cgtcactttt ccgttttttt ctaactgttc aataatattg atagcatcat
    21421 ttgcaggaat tgcgaaacca agaccttcta cagatgttcc tccatttgta gcaattttac
    21481 ttgaggtaat tccgataacc tgcccttgaa tattgatcag tgggccgcca gagttacctg
    21541 ggttaatagc agtatcagtt tggatggctt ttgtagaaat agcttgtcca tcttccgatc
    21601 ttaaggatac atttctattg agactggata cgataccttg agtgacagta tttgcatatt
    21661 cagaacctaa cgggctaccg atggcaatag cagtttctcc tacagttaac ttactagaat
    21721 caccaaactc agctactgtt gtcacttttt ctgaagagat tttgacgaca gcaatatcag
    21781 agaaagtgtc agctccgaca atttctccag gtactttagt cccatctgac aatcgaatat
    21841 ctactttgct ggcgccattt ataacgtgat tgttggtgac gatgtaagct tctttatcat
    21901 tctttttata aataactcca gatccttcac tagagattcg ctgagaatct gtgtcagtat
    21961 catcattgcc aaatacgcta ttttgtctgt ttgccgaata agtaataaca gaaacaacag
    22021 catcttttac tttgttaaca gcctgtgttg ttgaattttc gttcttatag gcagtttgtg
    22081 taatagtact attgttgtta gagttgttta cactactttt ttgagttagt tgagttattg
    22141 aaaaactacc caaggctcca ctaaaaaagc taatgacgat aacgactaat aattgaaacc
    22201 attttttgta aaatgttttt agatgtttca tatttgcctc catatgtttg aattactgaa
    22261 agtataaact gactagctta attataactt aaacacaaaa gttttacaca aactgtggat
    22321 aactcttttg aaactgtgat tttcttaatt gaaatctatt ttttattttg tgaataagat
    22381 gtgaaaaaat agagaatatg ttagaataga gtcatgaaaa ttaaagttgt aacagttggg
    22441 aaactgaaag aaaagtattt aaaagatggt atcgcagagt attcaaaacg aatttctaga
    22501 tttgctaagt ttgaaatgat tgagttatca gatgaaaaaa caccagataa ggccagtgaa
    22561 tcagaaaatc aaaagatttt agaaatagaa ggtcagagaa ttttatcaaa aattgctgac
    22621 cgtgatttcg ttattgtgtt agccattgaa gggaaaactt tcttctcaga agaatttagt
    22681 aagcagttag aagaaacttc tataaaagga ttttctactc ttacttttat tattggggga
    22741 agtttaggat tgtcatcatc tgtaaaaaat agagccaatc tttctgtcag ttttggtcgc
    22801 ctaaccttac cccatcagtt aatgagacta gttcttgttg aacaaatcta tcgcgctttt
    22861 acgattcagc agggattccc ctaccataaa tagaaaattg acttttaatt gaatttttgg
    22921 tagaataatt gtattaggtc tcatagctca gctggataga gcattcgcct tctaagcgaa
    22981 cggtcgcagg ttcgaatcct gctgggatca atataatagc aaagctggga attttcccgg
    23041 cttttttctt aaaaaagtac actttgggag aaaaaaatga cagttgagag aattttatct
    23101 aaaacgaaat tccattttgt ataatggttt ttgtaagtta gcttacaaga aaaaacattt
    23161 taggagattt tattatgaaa aacacagtta aattggaaca gtttgtagct ttgaaggaaa
    23221 aagacttaca aaagattaaa ggtggggaga tgaggttgtc aaaattcttc cgtgatttta
    23281 ttttacaaag aaaaaagtaa tgaaataagg ggaaagagta atggatttat ttggatttgg
    23341 gacggttatt gttcattttt taattattag tcacagttac cattttattt gtaaaggtca
    23401 aataaataga aaagaattat tcgtttttgg tgcttataca ttactaacag aaatagtatt
    23461 tgattttccc ttatatattc tatatttaga tgggttaggg attgaaagat ttttatttcc
    23521 tttgggatta tattcctatt ttcgatggat gaaacagtat gagagggata gaggactatt
    23581 cctaagttta ctactatctc ttttatatga gagcactcat aactttctgt ccgtaacttt
    23641 ctcctctata acaggagata attttgtttt acaatatcat ttcccattct ttttcgttgt
    23701 gacggtgtta acctattttg ttacattaaa aatcatttac tatttccatt tggaactagc
    23761 ctattttgac gaggactacc tttatccttt cttgaaaaaa gtattttttg ctttactatt
    23821 gctacatatt gtatctttcg tttcagatat ggtaagtacg attaaacatt tgaatagttt
    23881 tggaagtatt ttgtcatcta ttgtctttat ctctctcctt ttgaccttct ttgcaatgaa
    23941 ttctcataaa gttcaaatgg agaaagagat tgctttgaag cagaagaaat ttgaacagaa
    24001 acatttacag aattacacag atgaaattgt tggtctgtat aatgaaatcc gtggttttcg
    24061 acatgattat gctggaatgc ttgtcagcat gcagatggca attgacagtg gtaatttaca
    24121 ggaaattgac agaatttaca atgaagtttt agtcaaagca aatcataaat tgcgttcaga
    24181 taagtacact tactttgatt tgaacaacat agaagactca gctttacgaa gtttggttgc
    24241 tcagtcaatt gtctatgctc gaaataatgg tgtagagttt acactggaag taaaagatac
    24301 gattaccaag cttccaattg aactattgga tttggttcgt atcatgagcg ttttattgaa
    24361 taatgctgtc gaaggatcgg ctgatagcta taaaaagcag atggaagtag cagttattaa
    24421 gatggaaact gaaacagtta ttgtgattca gaattcatgt aaaatgacga tgactccttc
    24481 aggagatcta tttgccttag gattctccac taagggaaga aatcgcggag tcggattaaa
    24541 taatgtgaaa gaactactag ataagtacaa caatattatt ttagaaacag agatggaagg
    24601 cagtacattt agacaaatca ttagatttaa gagggaattt gaatgaaagt tttaatttta
    24661 gaagatgtta ttgaacatca agtgagacta gagagaatat tggatgaaat ttcgaaagaa
    24721 tcgaatattc caatatcata caagacaacg ggaaaagtcc gtgaatttga agaatacatt
    24781 gaaaatgatg aagtaaatca gctttatttc ctagatatcg atattcatgg aattgagaaa
    24841 aagggatttg aagtggctca gctcattcgt cattacaatc cttacgctat tatcgtcttt
    24901 atcactagtc gatcagagtt tgcgactcta acctataaat accaggtatc agccctagat
    24961 tttgttgata aggatatcaa tgatgagatg tttaagaaga gaattgagca aaatatcttc
    25021 tacacgaaga gtatgttact tgaaaatgaa gatgttgtag attatttcga ctacaattac
    25081 aagggaaatg atttaaaaat tccttaccat gatattttgt atattgaaac aacaggggtc
    25141 tctcataaat tgcgcattat tggtaagaat tttgcaaaag agttttatgg taccatgaca
    25201 gatattcagg aaaaggacaa acatactcag cgattttatt ctcctcataa gtcatttttg
    25261 gtaaatatag gcaatatcag agaaattgat cgaaaaaact tagaaattgt tttctatgaa
    25321 gaccatcgtt gtcctatttc aagattaaaa attagaaaat taaaagatat tttagagaaa
    25381 aaatctcaaa agtgattgac aattagcaag aaattgatat aatggttata tctgctacag
    25441 atagaaggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt aacacgggtt
    25501 cgaatcccgt acggactatt ttatccgcca tagctcagtt ggtagtagcg catgactgtt
    25561 aatcatgatg tcgtaggttc gagtcctact ggcggagtat agataaaagg gaacacagct
    25621 gtgttcctct ttttgtatca atttgtatca ccaagcattt tcataaggaa gtctgttatt
    25681 tcttgagaac tttctttttt tccatgtgca atccaagttt ggcagacacc aaaaagtgca
    25741 tgagttagat agatgctact atattctaat tcggtggtat ttagattcag ttgcataaat
    25801 cgcttttgta aatctgtact aagcatgata tgaagtttat ttcgtaagaa attttggatt
    25861 tctttagtcc cattttcaga aagaagggca gccagaagtg gttctgactc tagatattca
    25921 aaaacttcta aaatagcgtc tcttttgtga tgagcatgtt tttgaaaaat atattcaaat
    25981 gtatggaata gcttgctttg atagtgctca atcatatcat acttatcctt atagtgagta
    26041 tagaagctgg aacgactaat tccggctttt tctactaatt tgacagtaga aattttatca
    26101 aatggctgtt ccatcagtaa ttgtaccata gcattttcaa tagttcgctt tgtttttaag
    26161 cgtttgttac tttcttgcat atttcctcct tgtaaacaaa ttagactata tgtctaaaaa
    26221 tagatttttt atcttgtaat ttagattttt taatgtataa tctattatat caaaatttta
    26281 gacaatatgt ttaaaaaagg agaaactaag tttaaagaat ggaaagcaat ttaaaaaaaa
    26341 ccaaccttta ttattgtcat gatcgggatt tctcttattc cagatctgta caatatcata
    26401 tttttgtcat caatgtggga tccatatggg caattgtctg acttacctgt ggcagttgta
    26461 aataatgata aagaggcttc ctataatggt aatactatgg caataggaaa agacatggtg
    26521 tccaatttaa aagaaaataa aaccttggat tttcattttg tagatgaaga ggaaggaaag
    26581 aagggattgg aagatggcga ttactatatg gtagtgactt taccaagtga tttatctaaa
    26641 aaaacaacta cattatccaa tattcaatcg acagcagctt atcaatcatt gacaagtgag
    26701 caacaaactg ggataagtga ttctgtatct caaaattcaa ctgatagtat tcaatcggct
    26761 cagtcaattg tagctttagt acaaggttta cagggaagtt tagaaaactt acaaaatcaa
    26821 tcttctaatc tttcgacttt aaaaaatcaa gctaatcaag tattacctat tacttctact
    26881 tctttgatag gattgtcaag tggattaaca gagatacaag gagctgttac tagcaaatta
    26941 gttcctgcca gtcagttgat tgcatcaggt gtaaacgcat atactacagg tgttgataaa
    27001 gtttctcagg gcgcaagtca actaagtgaa aaaaatgcca ccttgacaca aaaatcttct
    27061 agattgacag caggagttga taaattacaa tcaggatctg ggcaattagc agacaaatcc
    27121 agtcagttac tttcaggtgc ttcttcatta gagaatggag ctaataaatt ggcagatgga
    27181 tctgggaaac tagcagaagg tggaacaaag ttaacttctg gattggaaga tttacagaca
    27241 ggacttgctt ctttaggaca aggactaggt aatgctagtg atcaactcaa atcagtatca
    27301 acagaatcta aaaatgcaga gattttgtca aatccactca atctttcaaa aagcagacaa
    27361 tgatcaagtt cttgtaaatg gaatcgcaat agctccttat atgatatcag ttgctctttt
    27421 tgttgcagca atatcaacaa atatgatatt ttcgaaattg ccttcaggac gtcatccaga
    27481 gatccgttgg gcttggttga aatctcgagc tgaaataaat ggtattatag ctgttttggc
    27541 aggaattttg gtatatggag gagttcatct tattggttta actgctaatc atgagatgag
    27601 aatatttatt ctcatcatcc taacaagttt agtattcatg tctatggtga ccactttaac
    27661 aacgtggaat agccgtatag gagctttctt ctcacttatt ttgcttttac tacagttagc
    27721 atcaagtgca ggtacttatc cacttgcttt gacaaatgat ttctttaaat ctattaatcc
    27781 ctggttacca atgagctatt cagtttcggg attacgacaa acaatctcca tcaacaagtc
    27841 attttcctag ctgtcatact agctctattt actggtttag gtatactagc ctatcaacat
    27901 aagaaaatgg aagaagatta aaaaaatcga ccgattaact ggtcgatttt ttatgcctta
    27961 gatgactttc gtctgtgatt atagattcca aatagtaaga gagaagtaaa ggaacagatt
    28021 gctccagtaa taaaaccatt gggaatgaag gaaagtgtaa tagttccttt ccccttggga
    28081 atgtcaactt tcataaatcc agtttgagct tgtttaattt ctattttctt accatcttgg
    28141 taggcagacc aacctttgtc ataaggaatg gtgaagaaaa tagatgtatc ttgttggaca
    28201 tcatatgtag caaaaacctt gtttttagaa gttgatactg tgacaggttg ttctttaatt
    28261 ttttgaattg ccttggtgaa agttttggta tctaaacgat agaaggtagg agattcaaat
    28321 gatacttgtg aatttccagg gaaactaaca ttgatattga aagttttttt ctctttagta
    28381 tatcctagat taaagaagga gaagacatta tcagttgtaa aagtcttttt ttcaccattt
    28441 acaaggatgt caaccttctt ttgtttatcg ttagaaaagt gaaggtttat gaaagagaga
    28501 taaacttggc tgttttctgg aacttcaatt tgatactgga ttgctgcatc ttcatttgaa
    28561 gaacttgtga cactaatcaa atcattagta ttttctattt tttctgtttt ttcataaggt
    28621 attggagaaa aataatcaaa attgacgtta gcaagttgat ttaaaaatga ggcctgatta
    28681 tccaaggtat gttcattgaa cttgacatca ttgtaaacag attgactagc aactgcaatc
    28741 ggaagagagt attgattttc atatagggta agattatctt tttgatagat atctttaaag
    28801 ccatacttat caataggact gtctgagata ttgtactgga taccaaataa actatcagcc
    28861 aaaatactat tatttgcata tcggagattg agattagtcc cagaggattt aaaaccaagt
    28921 ttatctaaag tagagcttga tgaacgattt cgaacagatg aaaattgaga gattccattg
    28981 tagttgaatt tcatactgtc atttcctgtc tgagtttgta gtttttcagt acgagtaaat
    29041 tgatttccaa tatatgttga gaaagattcc atagctggga tatctcgact ataagcactt
    29101 cgagaagcaa atccccattc cttagcaatt ccgtccattt gagatgaagc atttaaactc
    29161 atttcaacca gtataaataa agagattaga atggcaaata gattcacaga tataaacttt
    29221 ttgataactg caaggagtaa aagagaatag acaaccaaaa attcaagagt aagcagaata
    29281 ttcaaatctg ttaaaaaaga ataatgcgat tttagataga tggtagctaa aaatcctgtt
    29341 actacaagaa aaagcgaaac taaaaaattc cagactttaa gttctttcag acgctttaag
    29401 acttctgctg ctgtgtaaat taacaaggta gagaaaatcc aagcatagcg atgtaaaaac
    29461 atgtttggag tatgcatgcc ttgccaaaat aagtcaagag cttctatgta aaagcttgca
    29521 attagaaatg caaagaatat tacatatatg agtttcacgt gaaacttaat agatttcagc
    29581 gtaaaaaata aaatggtcaa aataaaggga aatagtccaa caaaaatcat tgggatggcc
    29641 ccatactttg ttgtgtcaaa ggaaccaatg aattgcttag caaagagatc aagataccag
    29701 ctactttcag tttgaaactt tgtaacttca gtcaattttt ccccatgtgt ctgtaaatca
    29761 aatagagtgg gaagagtcat aatcaaacta gccataccag ctaaaaagga gataactatg
    29821 aaatcaagaa cagatgattt tcgagtctta aagtcccacg aaatttgaca gagataccag
    29881 aaaataagaa acaatactgt catatatcca aaataataat tttgaataaa taagattgac
    29941 agacttgtaa agtacaatag gagtttcttt tcagttatca gtagatgtaa accagttata
    30001 attaaaggaa tcaagataaa aacatctagc caggttttta tctctaattg actgacagtg
    30061 aaactcatca gagcatagga agtagataag gctagtttta aagtctgagg gatagattga
    30121 aacaatttat tcaaactaaa aaaggttgac agaccaatca atccaaattt taagagagtg
    30181 gtcagataga cagcatctgg catgttcgtt agatcaaaaa agtaaactag aggcgcgaga
    30241 aaactaccca agtaataact agatagggca tagaagttta gccctagacc acttgtaaag
    30301 gtgtaaaaca gactactatt tccatgtagg atatttcgta aggctacatc aaaaataacg
    30361 tattgatgaa agccatctcc taatagagga gagttgtcgc tattccagta gataccttga
    30421 gatagatata ctccagacat aatcactaca ggaatgatga gagaaataaa ataggttcga
    30481 tatgttttta aaaatgattt catgttacct cgtagaatga tagaaaactc agttggttaa
    30541 cccaactgag ttttgaagtt ttatttagtc tttccaaagt tctttaactt ttgcttgtac
    30601 ttctgcattt tctaggaatt catcgtaggt ttcatcgata cggtcaatga cgccattttt
    30661 agataagaca atgatatggt tagccaaagt ttgaataaat tcgtggtcat ggctagcaaa
    30721 gatgattgat tctttaaagt ttttcaatcc atcattcaag cttgagatag attccaagtc
    30781 caagtgattt gttggatcat caagtacaag gacatttgat tttaagagca tgagttttga
    30841 aagcatgaca cgaacttttt ctccccctga caagacattt acaggtttgt taacttcatc
    30901 tccagagaag agcatacggc cgaggaagcc acgtaggaaa gtattgtcat cttcttcttt
    30961 acttgcgaat tgacgcaacc agtcaagaat tgattctcct cctgcaaaat cagctgagtt
    31021 atcttttggt aggtaagatt gactagttgt aactccccac ttgacagttc cttcatagtc
    31081 aatatctccc atgattgcac gaattaatgc agtcgtttga atatcatttt gtccaataag
    31141 tgctgtctta tcatctggac gcaagatgaa actaatatta tccaagatag tttcaccatc
    31201 aatctttaca gttagatttt ctactgtcaa gagatcatta ccaatctcac gttccgcttt
    31261 aaagttgata aatggatatt tacgactaga tggtacaatc tcttctagct caatcttatc
    31321 aagcattttc ttacgtgatg ttgcctgcct tgacttagaa gcattggcag agaaacgagc
    31381 aacgaattct tgcaattgtt taattttttc ttctgcttta gcattacggt ctgctagcaa
    31441 tttagcagca agctcagaag attccttcca gaagtcgtag tttccgacat agagtttgat
    31501 ttttccaaag tcaaggtcgg ccatgtgagt acaaactttg tttaagaagt gacggtcgtg
    31561 ggatactacg ataactgtgt tatcaaagtc aatcaagaag tcttctaacc aagtaatcga
    31621 ttggatatcc aaaccgttag taggctcgtc caagagaaga acatctggtt taccaaaaag
    31681 tgctttggcg aggagaacct ttactttttc accgttggcc aattcgctca tgttttggta
    31741 gtgtaattct tctggaatgt ttaggttttg aagtagttga gaggcttcac tctctgcttc
    31801 ccaacctcca agttcggcaa actctccttc gagttcggca gcacgaaccc cgtcctcgtc
    31861 tgagaaatct tccttcatgt agatagcatc tttctctttc atgatgctat aaagtttttc
    31921 atttcccatg ataacgacat caatggcacg ttcatcttcg tagtcaaagt gattttgacg
    31981 aagaacagag agacgttcat ctggaccaag agagatgtga ccagtagtag gttcgatatc
    32041 tccagctaaa atttttaaaa aggttgattt tccggcacca ttagcaccga ttaatccgta
    32101 agtatttcct tctgtaaatt tgatattgac atcatcaaaa agtttgcgat cactaaaacg
    32161 tagtgaaaca tcagatactg taagcaatat ttttctccta tatgtgtaat atatttattc
    32221 tactagaaaa tacagaaata ttcaaatttt tatttgtcaa ttttgtgtaa attatattta
    32281 cagtatcctt tacacaaatc tgtaaaaagc aaggctgatt tattttgata aattacggtt
    32341 atttcattaa aaaaatgcta taattgaaag gactatatcg aaggagaaca aaatgactaa
    32401 acccattatt ttaacaggag accgtccaac aggaaaattg catattggac attatgttgg
    32461 aagtctcaaa aatcgagtat tattacagga agaggataag tatgatatgt ttgtgttctt
    32521 ggctgaccaa caagccttga cagatcatgc caaagatcct caaaccattg tagagtctat
    32581 cggaaatgtg gctttggatt atcttgcagt tggattggat ccaaataagt caactatttt
    32641 tattcaaagc cagattccag agttggctga gttgtctatg tattatatga atctagtttc
    32701 gttagcacgt ttggagcgaa atccaacagt caagacagag atttctcaga aaggatttgg
    32761 agaaagcatt ccgacaggat tcttggtcta tccaatcgct caagcagctg atatcacagc
    32821 tttcaaggct aattatgttc ctgttgggac agatcagaaa ccaatgattg agcaaactcg
    32881 tgaaattgtt cgttctttta acaatgcata taactgtgat gtcttggtag agccggaagg
    32941 tatttatcca gaaaatgaga gagcagggcg tttgcctggt ttagatggaa atgctaaaat
    33001 gtctaaatca ctaaataatg gtatttattt agctgatgat gcggatactt tgcgtaaaaa
    33061 agtaatgagt atgtatacag atccagatca tatccgcgtt gaggatccag gtaagattga
    33121 gggaaatatg gttttccatt atctagatgt ttttggtcgt ccagaagatg ctcaagaaat
    33181 tgctgatatg aaagaacgtt atcaacgagg tggtcttggt gatgtgaaga ccaagcgtta
    33241 tctacttgaa atattagaac gtgaactggg tcctattcgt gagcgccgta ttgaatttgc
    33301 taaggatatg ggagaagttt ataatatgat tcaaaaaggt agtgaaagag cgcgtgaagt
    33361 tgcgggtcaa accctatctg aggtaaaagg ggcaatggga cttcattact ttaactaagt
    33421 ttattttaca agaaactatc atttctatct cgaagaaaag atagtttttt atttacccct
    33481 gtaacatttg acaaattttt atagaatggt atgatagata caatataaaa agagtcaagc
    33541 tcaaaaagaa agaaaagagg aaacttcgaa tgtctaattg ggacactaaa tttttgaaaa
    33601 aaggttttac ctttgatgat gtattgctta ttccagctga aagtcatgtg ttgcctaacg
    33661 atgcagattt aacaactaaa ttggcagata atttgacttt aaatatccca attattaccg
    33721 ctgccatgga cacagttaca gagagtcaaa tggccattgc tattgctcgt gcaggtggtc
    33781 tcggagttat ccataaaaac atgtcaattg ctcaacaagc agacgaggtt cgtaaggtaa
    33841 aacgttctga aaatggagtt attattgatc cgttcttctt gacgcctgaa catacaattg
    33901 ctgaagcaga tgagcttatg ggtcgttacc gcatcagtgg tgttccagtt gttgaaacac
    33961 ttgaaaatcg taaattggtt ggtattttga caaaccgaga tcttcgtttt atttcagatt
    34021 ataatcaacc aatttcaaac catatgacta gtgaaaatct tgttactgct cctgtgggta
    34081 cggatcttgc aacggctgag agtattcttc aagagcatcg tattgaaaaa cttccgttgg
    34141 tcgatgaaga aggcagtctt tctggtttga tcactatcaa agatattgaa aaagttattg
    34201 agtttccaaa tgcggctaaa gatgaatttg gtcgtcttct agttgcaggt gcagtaggtg
    34261 ttacttcaga tacatttgaa cgtgcagagg ctctttttga ggcaggagcg gatgcgattg
    34321 ttattgatac tgcacatggt cattctgcag gtgtcttgcg taaaattgcc gagattcgtg
    34381 ctcatttccc agatcggact ttgattgctg gaaatattgc tactgctgaa ggtgcacgtg
    34441 ccctttatga agcgggtgta gacgttgtta aggttggtat tggaccaggt tctatctgta
    34501 ctactcgtgt gattgctggt gttggtgttc cgcaagtaac agctatctac gatgctgcag
    34561 ctgttgcgcg cgaatatggt aaaacgatta ttgctgacgg tgggatcaag tattctggag
    34621 atattgtaaa agcacttgct gcaggtggaa atgctgttat gcttggatct atgtttgctg
    34681 gaactgatga agctccaggc gaaactgaaa tcttccaagg acgtaaattc aagacttacc
    34741 gtggtatggg atcaattgct gctatgaaga aaggttcaag cgaccgttat ttccaaggtt
    34801 ctgtcaatga agcaaacaag ctcgttccag aaggaattga aggtcgtgtt gcttataaag
    34861 gagcggcagc tgatattgtt ttccaaatga ttggtggtat tcgctctggt atgggttact
    34921 gtggtgcagc taaccttaaa gaactacacg ataatgctca atttattgaa atgtctggtg
    34981 ctggtttgaa agaaagccat cctcatgatg tgcaaattac taatgaggca ccaaattatt
    35041 ctatgtaaaa aacaatgaaa agaactccag tgaaaacagg agttctttta caatgttgtc
    35101 aatttccatt tacagaagct ttaccatcct gaatagtgaa gatacttaga ttttctggca
    35161 gattttgaag atggtctaag cttgttgttg tgataaaggt ttggattgat tgagaaatcg
    35221 tttctaataa ttttaactgt ctagtgttgt caagttcact catcacatcg tcaagcagta
    35281 atataggaga ttctgtggta atgctttcca ttaattcgat ttctgctaat tttatcgaga
    35341 ggacgagact acgatgttga ccttggcttc cgaaactagc atccatccca tttatataaa
    35401 aagaaatgtc atctcgatga ggaccgacac cagtattctt tttaaataaa tctctggatc
    35461 tacttttttc taaagcaatt ttgaaagatt cggataagtt ttgtttgtca gttatattga
    35521 cagaagattg ataggatatt gacaactctt cgatctgatt agagagttca aaatgtttct
    35581 tacgcccaaa tgattctagt ttttttatga aatctaagcg gtgattcatt acacgacatc
    35641 cataatcaac tagctgatca tctaacacag aaaggaatgt ttcatctatt ttttgagctg
    35701 attttaggta agtgtttctt tgctttagga tgtggttata attggttaag tcagataaat
    35761 agattggctt aatttgccca agttccatat caatgaattt tcgtcgaatc gaaggtgctc
    35821 ctttaattag ttgtaaatct tcaggagcaa ataagacaac attcatgtgt cctacataat
    35881 ctgaaaggcg tgcctgtttt aagtgattaa cttttgttac acggcctttt tgtgttagtt
    35941 cgatttctag gggaatggat ccagtttttt tctgaacgag acctgaaaga tgaagttgtt
    36001 cctcatcaaa atgaatgaga tttttatctg ttcgagttcg atgactacgc gttaaggcta
    36061 aaaaatagat agcctctaac atgtttgttt ttccttgtgc attacgtccc aaaaagacat
    36121 tcaatttagg attaaagtct attttcgttt ctttgtaatt acgaaaagtc ttgagagata
    36181 gatgttgtag ccacatgatt atctaccagg gaatcgtgga gcttgttggc ttttaggtga
    36241 tgaagcaggt ttcgatttgt cttttttaac tcccttattc atctttttga caagtttagc
    36301 gatccgttct ttttcaactt tatcagcttg gtattcatct tgttcttcag aagtaggttg
    36361 tgtcaacaag atgtcaatgt tcatgtcagg gatgtcaact ttatcgccaa tacgaagttt
    36421 ttttccacga cgactctcta attccctatt aaagtaaaca gaatgttcag agagaaatga
    36481 tttaatagct cctccgctat gtgtaattcc aagttctttg agtagtgctt ggagggtaat
    36541 aaattcttca aataatttgt attccataat tcacctcaat ctttggtatt ataccatatt
    36601 ttcctaaaaa tagtgagaga gacagcgaga aatgtaagcg atttttattt caaaagtgtt
    36661 acagggaaca agaaaatttc aggttttcgt gatataatag aagtctgtat ataaggaggt
    36721 aaatcatgga gttagtgcat ggaatttcaa cacattttat ccaatcaaaa aagtttaaaa
    36781 caaacaaaat taccgtgcgt tttaccgctc cattatccct tgatacgatt gcaggtcaca
    36841 tgttgagtgc aagtatgcta gagactgcta atcagatgta ccccacttct caagatttga
    36901 ggagacactt ggccagtcta tacggtacag atatgtcaac caattgtttc agaagagggc
    36961 aaagccacat tatagaattg acatttacct atgttcgtga tgagttttta agtaggaaaa
    37021 acgtgctaac ctctcagatt ttggaacttg taaaagaaac tcttttttca cccgcagtag
    37081 ttgataatgg gtttgatccg gccttatttg aaattgagaa aaaacaattg ctagcaagtt
    37141 tagcagctga tatggatgat tctttttatt ttgcacataa agaattggat aaattgtttt
    37201 ttcatgatga acgtcttcaa ttggaatata gtgatttacg aaatcgtatt ttagctgaaa
    37261 ctccacaaag ttcttattct tgtttccaag aatttttagc caatgatcga atagatttct
    37321 ttttcctagg tgattttaat gaggttgaaa ttcaaaatgt attagaatca tttggcttta
    37381 aaggtcgaaa aggagatgtg aaggttcagt attgtcaacc ttattctaat atccttcagg
    37441 aaggtatggt tcggaaaaat gtgggacaat ccattttgga attaggttat cattaccgtt
    37501 ctaaatatgg tgatgagcaa catttaccca tgattgtaat gaatggttta cttggtggat
    37561 ttgctcactc taagctcttt acaaatgtcc gtgaaaatgc tggattagct tataccattt
    37621 caagtgagct tgatttattt agtggattct tgaggatgta tgctggtatc aatcgagaaa
    37681 atcgtaacca ggctcgtaaa atgatgaata atcaactgct tgatttaaaa aaaggttatt
    37741 ttacagagtt tgagttaaat cagaccaagg aaatgattcg ttggtcgttg ttactttctc
    37801 aagataatca atcttcattg attgaacgtg cttatcaaaa tgccttattt ggaaaatctt
    37861 cagcagactt taaaagttgg attgcaaagc ttgaacaaat tgacaaagat gctatttgta
    37921 gagtagctaa taatgtgaaa ctacaagcga tttactttat ggaaggaata gaatgacaaa
    37981 ggttgttttt gaagaaaaat actatccagc tgtaaaagaa aaggtttatc gaactcgttt
    38041 ggccaacgga ttgacagttg ctcttttgcc taaaaaggaa tttaaagagg tttacgggag
    38101 tgtcactgta cagtttggtt cggtagatac gtttgtcaca gaagttgacg gatatgtaaa
    38161 acaatatcct ggaggaattg ctcattttct tgaacataaa ttatttgaga gagaagattc
    38221 tagtgatttg atgtcggctt ttacgagtct aggtgcagat agtaatgcct ttacaagctt
    38281 tacaaaaaca aactatcttt tttcagcaac ggattatttt ttagaaaatt tagatttact
    38341 tgatgaattg gtaacatcag cacactttac tgaagcttcc attctgacag agcaggatat
    38401 tattcagcaa gaacgagaaa tgtaccaaga tgatccagat tcgtgtttat tcttttcaac
    38461 tttagcgaat ttgtatcctg gtacaccttt agcaactgat atagttggaa gtgaggagtc
    38521 catttcccaa atcaatctaa ctaatttgca agaaaatttt acaaagtttt acaaacctgt
    38581 aaacatgtct ctgtttttag ttggtaattt tgatgtggag cgagtacagg actattttga
    38641 aagcaaagaa ctgaaagatt cagattttca ggaagtagca agagaaaagt tgtttttaca
    38701 gcctgtaaag ccaacagata gtatgagaat ggaagtatct tctcccaaac tagcgattgg
    38761 agttagaggt aagcgagaag tttctgaagc ggattgctat cgacatcata ttttattaaa
    38821 attattgttt gcaatgatgt ttggttggac ttcggatcgt tttcaaaaat gttatgaatc
    38881 aggtaaaatt gatgcgtcct tatctctgga agttgaaata acaagtcgct ttcattttgt
    38941 catgttgaca atggatacga aagagccagt tgctttgtct catcaattta ggaaggctat
    39001 tcgtaatttt acaaaggatt tagatattac agaggaacat ttagatatta tcaaaagaga
    39061 gatgtttggc gaatttttca gtagcatgaa ctctcttgaa tttattgcaa cgcaatatga
    39121 tgcttttgaa aatggtgaga caatttttga tttgccgaaa attttacagg aaattacttt
    39181 agaggatgtc cttgatgctg gacatcattt aatagatgat ggtgacatag ttgattttac
    39241 aatatttcca tcgtagtaac ctatcataat agacactaga aagaagggat gacaagtatg
    39301 agaaaaaaaa caattggaga ggttttacga ttagctagaa tcaatcaggg attgagttta
    39361 gatgaattgc agaaaaagac agaaatccag ttagatatgt tggaagcaat ggaagcagac
    39421 gatttcgatc aacttccaag tcctttttac acgcgttctt tcttgaaaaa atatgcatgg
    39481 gctgttgagt tagatgacca aattgttttg gatgcttatg attctgggag tatgattact
    39541 tatgaggaag tagatgttga tgaagatgag ttgacaggtc gtagacgttc aagtaagaaa
    39601 aagaagaaaa aaacatcatt tttaccttta ttttatttta tcctttttgc tttatcgatt
    39661 ttaatttttg tgacttatta tgtttggaac tatattcaaa ctcaaccaga ggagccttct
    39721 ctttctaatt acagtgtggt tcaatcaaca agttcaacta gctctgttcc ccactcctca
    39781 agtagtagtt cttctagtat agaatcagct ataagtgtat caggcgaagg aaatcatgta
    39841 gaaatcgctt ataagacaag taaggaaaca gttaaattgc aattggcagt ttcagatgtt
    39901 acaagttggg tcagtgtttc agaaagcgaa cttgagggcg gtgtaacctt atcgccaaag
    39961 aagaaaagtg cagaagcaac agttgcaact aaaagtcctg taacaattac gttaggtgtt
    40021 gtaaaaggtg ttgatttgac agtagataat cagactgttg atttatcgaa attaacagct
    40081 cagactggac aaatcactgt aacctttact aaaaattaag gaaaaacgaa tgaaaaaaga
    40141 acaaattccc aatctcttaa caataggtcg aattctcttt atacctattt ttatctttat
    40201 tttaacgata ggaaattcga tagagagtca tatagttgca gctattatct ttgctgttgc
    40261 cagtattacc gactatttag atggatattt agctcgtaaa tggaatgtgg tcagtaattt
    40321 tggtaaattt gcagatccta tggcggataa gttactagtt atgtcggctt ttattatgtt
    40381 gattgagtta ggtatggctc cggcttggat tgttgcagtg attatctgtc gtgagttagc
    40441 tgtgacaggt ttaaggcttt tattggttga aactggtgga acaattttag cagcagcaat
    40501 gcctggaaaa attaaaactt ttagtcagat gtttgccatt attttcttgc tattacattg
    40561 gactttgctt ggtcaagttc tactttatgt agccttattt ttcactatct actctggcta
    40621 tgactatttc aagggtagtg cctatgtatt taaagggaca tttggttcga aatgaaatca
    40681 ataattgatg taaaaaatct ttcttttcgc tataaagaaa atcagaacta ctacgatgtg
    40741 aaggatatta cgtttcacgt gaaacgtgga gaatggcttt cgattgtagg gcataatggt
    40801 agtggtaaat caacgacggt tcgattaatt gatggcttac tggaagcaga atccggagag
    40861 attgtaattg atggccaacg tttgactgag gaaaatgttt ggaatatacg tcgtcaaatc
    40921 ggtatggttt ttcaaaatcc agacaatcaa tttgttggag cgactgttga agatgatgtt
    40981 gcttttggtt tggaaaatca gggactttct cgtcaagaaa tgaaaaagag agtggaagaa
    41041 gctctggctt tagttggcat gttggacttt aaaaagagag agccagcgcg tctatcaggt
    41101 ggccaaaagc aacgtgtggc cattgcaggt gttgtagccc taagaccagc tattttaatc
    41161 ttagatgaag caacgagtat gttggatcct gaggggcgta gagaacttat tgggacagta
    41221 aaaggaattc gaaaagacta tgatatgacg gtcatttcta ttacccatga tttggaagaa
    41281 gtcgccatga gtgatcgcgt attggtcatg aaaaaagggg aaattgaatc aactagtagt
    41341 ccaagggagc ttttctctcg aaatgattta gatcaaattg gattagacga tccttttgct
    41401 aatcaattaa aaaaatcttt gagccagaat ggctatgatt tacctgaaaa ttatttgaca
    41461 gaaagtgagc tagaggataa gctatgggaa ttgctctaga aaatgtgaat tttatatatc
    41521 aagaaggtac tcccttagct tcagcagctt tgtcggatgt ttctttgacg attgaagatg
    41581 gctcttatac agctttaatt gggcacacag gtagtggtaa atcaactatt ttacaactct
    41641 taaatggttt attggtgcca agtcaaggga gtgtgagggt ttttgatacc ttaatcacct
    41701 cgacttctaa aaataaagat attcgtcaaa ttagaaaaca ggttggcttg gtatttcagt
    41761 ttgctgaaaa tcagattttt gaagaaacgg ttttgaagga cgttgctttt ggaccgcaaa
    41821 attttggagt ttctgaagaa gatgctgtga agactgcgcg tgagaaactg gctctggttg
    41881 gaattgatga atcacttttt gatcgtagtc cgtttgagct gtcaggggga caaatgagac
    41941 gtgttgccat tgcaggcata cttgccatgg agccagctat attagtctta gatgagccaa
    42001 cagctggtct agatcctcta gggagaaaag agttgatgac cctgttcaaa aaactccacc
    42061 agtcagggat gaccatcgtc ttggtaacgc atttgatgga tgatgttgct gaatatgcga
    42121 atcaagtcta tgtaatggaa aagggacgtt tagtaaaggg gggcaaacca agtgatgtct
    42181 ttcaagacgt tgtttttatg gaagaagttc agttgggagt acctaaaatt acggcctttt
    42241 gtaaacgatt ggctgataga ggcgtgtcat ttaaacgatt accggttaag atagaggagt
    42301 tcaaggagtc gctaaatgga tagtatgatt ttggggcgtt atatcccagg ggattcgatt
    42361 gttcaccgat tggatccacg tagcaaattg cttgctatga tgctactgat tttgattgtg
    42421 ttttgggcta ataacccctt gacgaatctg attcttttta tagcgacagg gatatttatt
    42481 gccttgtcag gagtatctct ttcatttttt attcagggct tgaagtctat gtttttcttg
    42541 attgccttca caactatttt tcaactattt ttcatttcta atgggaatgt tttatttgag
    42601 ttttcgtttg tgagaatcac ggattatgct ttgcaacaag ctgggattat tttttgtcgc
    42661 tttgtattga ttattttctt ttcaactttg ttaaccttaa caaccatgcc tttaagtttg
    42721 gcatcagctg tcgaagcttt attagcacct ttaaagcgtg tgaaagttcc agttcatgaa
    42781 attggattga tgctgtctat gagtttgcgt tttgtcccaa ccttgatgga tgatacgact
    42841 cggattatga atgcacagaa agctcgtgga gtggattttg gagaaggaag catcgttcaa
    42901 aaagtaaagg cgatgattcc cattttgatt cctctttttg cgacaagttt aaaacgtgca
    42961 gattccttgg ctatcgctat ggaagcgcgt ggctatcagg gtggaaaagg cagaagtcaa
    43021 taccgacaat tgaaatggac tctaaaggat acgctgacca ttcttgttat tctcgtactt
    43081 ggttgttgtt tatttttctt aaaatcttag tagctttcag gaattgataa aaagttactg
    43141 taacagtttt tgatataaag gtagggatat gaaccgtttt aaaaaatcaa aatatgtcat
    43201 tattgttttt gtcactgttc tgcttgtgtc agctctctta gcgacgactt attcaagtac
    43261 aattgtgaca aaattaggag atggaatctc attggttgat agagttgtac aaaaaccttt
    43321 tcagtggttt gattctgtca aatcagattt ggctcatttg acacgaacat ataatgaaaa
    43381 tgaaagtttg aagaaacagc tttaccaatt agaagttaaa tcaaatgagg tggaaagttt
    43441 aaagacagaa aatgaacaac tgcgccaatt gcttgatatg aagtctaaat tgcaagccac
    43501 aaagacttta gcagcagatg ttattatgcg ttctccggta tcttggaagc aggagttgac
    43561 cttagatgca ggtagatcaa aaggtgcttc tgagaacatg ttagctattg caaatggtgg
    43621 cttgattggg agtgtttcaa aagtagagga gaactctact atagtcaacc ttctgacaaa
    43681 tacggaaaat gctgataaga tttctgttaa aattcaacat ggctctacta caatttatgg
    43741 aattattatt ggctatgaca aggaaaatga cgttcttaaa attagccaat taaatagtaa
    43801 tagcgatatt agtgcgggag ataaggtgac tactggtgga ttaggaaact ttaacgttgc
    43861 tgatattcct gttggtgaag tggttgccac aacgcatagt acagactatt tgacacgaga
    43921 agtaactgtt aaattgagtg cagatactca taatgtagat gtgatagaat tagtggggaa
    43981 ttcataatga gacagttgaa gcgagttgga gtatttttat tgcttccttt ctttgttcta
    44041 attgacgccc atattagcca gcttctgggc tcatttttcc cccatgtaca tttggctagt
    44101 cattttcttt ttctatttct cttatttgag acgatagaag tatcagagta tctctaccta
    44161 gtctattgtt ttgttatagg cttggtttat gatgtttact ttttccatct aatagggatt
    44221 acaactctct tatttatctt attgggagcc ttccttcata aattgaatag tgttattttg
    44281 ttgaatcgtt ggacaagaat gctagctatg attgtgctga cattcctgtt tgaaatgggt
    44341 agttatcttt tggcttttat ggtagggttg acagtagata gcatgtcgat ttttatagtc
    44401 tatagcttgg taccgacgat gattttaaat tttttatgga ttactgtttt tcaatttatt
    44461 tttgaaaaat attatctata agaacgacat ataaatgtaa caaaggcgta atatttatta
    44521 ggcctttttt tggtatacta gtattgtctt taaaagaagg agtatctacg taatatgaag
    44581 aaaaaaatct tagcgtcact tttattaagt acagtaatgg tttctcaagt agctgtttta
    44641 acaactgcgc atgcagaaac gactgatgac aaaattgctg ctcaagataa taaaattagt
    44701 aacttaacag cacaacaaca agaagcccaa aaacaagttg accaaattca ggagcaagta
    44761 tcagctattc aagctgagca gtctaacttg caagctgaaa atgatagatt acaagcagaa
    44821 tctaagaaac tcgagggtga gattacagaa ctttctaaaa acattgtttc tcgtaaccaa
    44881 tcgttggaaa aacaagctcg tagtgctcaa acaaatggag ccgtaactag ctatatcaat
    44941 accattgtaa actcaaaatc aattacagaa gctatttcac gtgttgctgc aatgagtgaa
    45001 atcgtatctg caaacaacaa aatgttagaa caacaaaagg cagataaaaa agctatttct
    45061 gaaaaacaag tagcaaataa tgatgctatc aatactgtaa ttgctaatca acaaaaattg
    45121 gctgatgatg ctcaagcatt gactacgaaa caggcagaac taaaagctgc tgaattaagt
    45181 cttgctgctg agaaagcgac agctgaaggg gaaaaagcaa gtctattaga gcaaaaagca
    45241 gcagctgagg cagaggctcg tgcagctgcg gtagcagaag cagcttataa agaaaaacga
    45301 gctagccaac aacaatcagt acttgcttca gcaaacacta acttaacagc tcaagtgcaa
    45361 gcagtatctg aatctgcagc agcacctgtc cgtgcaaaag ttcgtccaac atacagtaca
    45421 aacgcttcaa gttatccaat tggagaatgt acatggggag taaaaacatt ggcaccttgg
    45481 gctggagact actggggtaa tggagcacag tgggctacaa gtgcagcagc agcaggtttc
    45541 cgtacaggtt caacacctca agttggagca attgcatgtt ggaatgatgg tggatatggt
    45601 cacgtagcgg ttgttacagc tgttgaatca acaacacgta tccaagtatc agaatcaaat
    45661 tatgcaggta atcgtacaat tggaaatcac cgtggatggt tcaatccaac aacaacttct
    45721 gaaggttttg ttacatatat ttatgcagat taatttacag agggactcga atagagccct
    45781 cttttcaggt tttaccgtga caatccctat taaaaattat atcaaaatag cttgaaaata
    45841 ttggaaaagt atggtagaat gaaaattgtc gtgtgaacga taatactcat tcttgatgaa
    45901 ttgtgaagca gttgcccttg ggtcgttttg cgagttgaag tcaagaagag gaaaaaaaca
    45961 aaaaggagaa atactcatgg cagtaatttc aatgaaacaa cttcttgagg ctggtgtaca
    46021 ctttggtcac caaactcgtc gctggaatcc taagatggct aagtacatct ttactgaacg
    46081 taacggaatc cacgttatcg acttgcaaca aactgtaaaa tacgctgacc aagcatacga
    46141 cttcatgcgt gatgcagcag ctaacgatgc agttgtattg ttcgttggta ctaagaaaca
    46201 agcagctgat gcagttgctg aagaagcagt acgttcaggt caatacttca tcaaccaccg
    46261 ttggttgggt ggaactctta caaactgggg aacaatccaa aaacgtatcg ctcgtttgaa
    46321 agaaattaaa cgtatggaag aagatggaac tttcgaagtt cttcctaaga aagaagttgc
    46381 acttcttaac aaacaacgtg cgcgtcttga aaaattcttg ggcggtatcg aagatatgcc
    46441 tcgtatccca gatgtgatgt acgtagttga cccacataaa gagcaaatcg ctgtcaaaga
    46501 agctaaaaaa ttgggaatcc cagttgtagc gatggttgac accaatactg atccagatga
    46561 tatcgatgta atcatcccag ctaacgatga cgctatccgt gctgttaaat tgatcacagc
    46621 taaattggct gacgctatta tcgaaggacg tcaaggtgag gatgcagtag cagttgaagc
    46681 agaatttgca gcttcagaaa ctcaagcaga ttcaattgaa gaaatcgttg aagttgtaga
    46741 aggtgacaac aaatagtaat tacctaggag ggcggggctt agcccggctc tcctattttc
    46801 aaaaaatata ggagaattaa aatggcagaa attacagcta aacttgtaaa agagttgcgt
    46861 gaaaaatctg gtgccggtgt tatggacgct aaaaaagcgc ttgtagaaac agacggtgac
    46921 atcgaaaaag cgattgaatt gcttcgtgaa aaaggtatgg ctaaggcagc taagaaagct
    46981 gaccgtgttg ctgcagaagg tttgactggt gtttatgtta acggtaatgt tgcagcagtt
    47041 attgaagtaa acgctgaaac tgacttcgtt gcaaaaaacg ctcaattcgt tgaattggta
    47101 aatactacag ctaaagtcat tgctgaagga aaacctgcta acaatgaaga agctcttgct
    47161 ttgataatgc cttcaggtga aactcttgaa gctgcatacg tatctgcaac agcaactatc
    47221 ggagagaaaa tctcattccg tcgctttgca ttgattgaaa aaacagacgc acaacacttt
    47281 ggagcatacc aacataacgg tggacgtatc ggtgttattt cagttgttga aggtggagac
    47341 gaagcacttg ctaaacaatt gtcaatgcac atcgcagcga tgaaaccaac agttctttct
    47401 tacaaagaat tggatgagca attcgttaaa gatgagttgg cacaattgaa tcacgttatc
    47461 gaccaagaca acgaaagccg tgcaatggtt aataaaccag ctcttccaca cttgaagtat
    47521 ggatcaaaag ctcaattaac tgatgatgtt attgctcaag ctgaagctga catcaaagct
    47581 gaattggctg cagaaggcaa accagaaaaa atctgggaca aaattattcc aggtaaaatg
    47641 gatcgcttca tgcttgataa cactaaagtt gaccaagctt acacacttct tgcacaagtt
    47701 tacatcatgg atgacagcaa gacagttgaa gcataccttg aatcagttaa cgcttcggta
    47761 gttgagtttg ctcgctttga agttggtgaa ggtatcgaga aagctgcaaa cgacttcgaa
    47821 gctgaagttg cagctacaat ggcagcagcc ttgaataact aataatagaa aggaagcaaa
    47881 ttgcttcctt ttttgtatgc agtcgatcct tatagggaga gcttcctatt ttcaaggtaa
    47941 aaataaaaag ccctataata agggccaatt gtatttagga gactaaactt caaattcata
    48001 gagtgctgta gagagataac gttcaccgtt atctggtgct agagcaagga cttttttacc
    48061 tgtacctaat tttttggcaa cctcgatggc tccgtagata gctgcagctg aggaaatccc
    48121 tacaaggaag ccttcttttc caccaatttc acgtccgagt gcaagagcat catctgatgt
    48181 tacacgaacg ataccatcat aggctttagt atcaagtgta tcaggaataa atccagctga
    48241 gataccttga attttgtgag gaccaggttt ttcaccagat agaatagcag attcatcagc
    48301 ttccactgca taaacttgaa tgttagaatt ttctgatttg agtgcatgag aaacaccaga
    48361 aatcgttcca ccggtaccta ctccagcaac aaaggcatct aatccatctt taccgaaagc
    48421 agctagtatc tcagctcctg ttgttctttc gtgtacttct ggattagctg gattgtcaaa
    48481 ttgaagagga aggaaaccat cacgttcagc agcgatttct tgagccttag caatagcacc
    48541 tttcattccc tcgctaccag gagttaggac gagttcagca ccataagctt ggataatttt
    48601 acgtcgttct acactcatag tttcaggcat aacgatgacg actttatacc ctttagcagc
    48661 acctacccat gaaagtccaa taccagtgtt tccacttgtt gcttcaacaa tagtagaacc
    48721 aggtttcaga ataccatctt gttcagcttt ttcaatcatg ctaagggcaa tacggtcttt
    48781 tacagatgaa ccaggattaa atgcttcaag ctttatatag acgtctgcag caccttctgg
    48841 cacgatgttg ttaagtttaa caatcggtgt ttgaccgatt aattcagtaa tgttgttata
    48901 aatagacata tgaatacctc tttgtataag atatctttag tataacgcta tctataccat
    48961 ttgtaaaata tagaaatcct atcgaagcga taggatttct atatatcata gatcaaagtc
    49021 attaattttc aagtgattgc gttcagctaa ttctagtaaa taggtgtgaa ggaaaacgat
    49081 atcaggtttc gtttgaattg cttcattttc tagtatattt tggtacgcat ctttttattt
    49141 tgctcgctaa agtagttgtg agaatgtcaa cgaaacgctg tattattcat tgtttacact
    49201 aagtttacag gaacttcaac ctctcgtaaa ccttggtcag ttaaagtgac ttttccatta
    49261 aaaaactcca caagtgcagc tttaatagtt tctttttctt ccttatcaac ataaatcatc
    49321 gtatcgactt gatctgtaaa gtttgtatcc agctccatga gatcatgttc tttaaggaag
    49381 ttactgtact cttggtactg agcataagac atttgaatag caatgccagc ctgttctttt
    49441 atttcaataa taccaatttc tttgacagct aaggcgacac tgccggcgta agcacgaatt
    49501 agtcctccag cgcctagttt aataccacca aagtagcgtg tcacgaccac acagacattg
    49561 gtgagattgt gattttctag taccccaagc atgggaacac cagcagtacc actaggctca
    49621 ccatcatcac ttgtacgttt aatttcacta cgttctccaa taataaaggc agagcagtta
    49681 tgtgtcgctt tgtagtgttc ttttttgatg gcagtaatga agtcacgagc ctcttcttcg
    49741 ctataaacac gcttggcatg gcagataaag cgagattttt tgatttcttc ttggacttgg
    49801 ccgtcctctt taattatcct aaattccatg atttaattgt actaaaaaat aatctaaagt
    49861 gctagttttt acgaataaag aagtatgaaa gtaaatttag attatctcgg tcgtttattt
    49921 actgagaatg aattaacaga agaagaacgt cagttggcgg agaaacttcc agcaatgaga
    49981 aaggagaagg ggaaactttt ctgtcaacgt tgtaatagta ctattctaga agaatggtat
    50041 ttgcccatcg gtgcttacta ttgtcgagag tgcttgctga tgaagcgagt cagaagtgat
    50101 caaactttat actattttcc gcaggaggat tttccgaagc aagatgttct caaatggcgc
    50161 ggccaattaa ctccttttca agagaaggtg tcagagggac tgcttcaagc agtagacaag
    50221 caaaagccaa ccttagttca tgcggtaaca ggagctggaa agacagaaat gatttatcaa
    50281 gtagtggcta aagtgatcaa tgcgggtggt gcagtgtgtt tggctagtcc tcgcatagat
    50341 gtttgtttgg agctgtacaa gcgcctgcaa caggattttt cttgcgggat agctttgcta
    50401 catggagaat cggaacctta ttttcgaaca ccactagttg ttgcaacaac ccatcagtta
    50461 ttgaagtttt atcaagcttt tgatttgctg atagtggatg aagtagatgc ttttccttat
    50521 gttgataatc ccatgcttta ccacgctgtc aagaatagtg taaaggagaa tggattgaga
    50581 atctttttaa cagcgacttc gaccaatgag ttagataaaa aggtccgttt aggagaacta
    50641 aaaagactga atttaccgag acggtttcat ggaaatccgt tgattattcc aaaaccaatt
    50701 tggttatcgg attttaatcg ctacttagac aagaatcgtt tgtcaccaaa gttaaagtcc
    50761 tatattgaga agcagagaaa gacagcttat ccgttactca tttttgcttc agaaattaag
    50821 aaaggggagc agttagcaga aatcttacag gagcaatttc caaatgagaa aattggcttt
    50881 gtatcttctg taacagagga tcgattagag caagtacaag cttttcgaga tggagaactg
    50941 acaatactta tcagtacgac aatcttggag cgtggagtta ccttcccttg tgtggatgtt
    51001 ttcgtagtag aggccaatca tcgtttgttt accaagtcta gtttgattca gattggtgga
    51061 cgagttggac gaagcatgga tagaccgaca ggagatttgc ttttcttcca tgatgggtta
    51121 aatgcttcaa tcaagaaggc gattaaggaa attcagatga tgaataagga ggctggtcta
    51181 tgaagtgctt gttatgtggg cagactatga agactgtttt aacttttagt agtctcttac
    51241 ttctgaggaa taatgactct tgtctttgtt cagactgtga ttctactttt gaaagaattg
    51301 gggaagagaa ctgtccaaat tgtatgaaaa cagagttgtc aacaaagtgt caagattgtc
    51361 aactttggtg taaagaagga gttgaagtca gtcatagagc gatttttact tacaatcaag
    51421 ctatgaagga ttttttcagt cggtataagt ttgatggaga cttcctgtta agaaaagttt
    51481 tcgcttcatt tttaagtgag gagttgaaaa agtacaaaga gtatcaattt gttgtaattc
    51541 ccctaagtcc tgatagatat gctaacagag gatttaatca ggttgagggc ttggtagagg
    51601 cagcaggctt tgagtatctg gatttattag agaaaagaga agagagagcc agttcttcta
    51661 aaaatcgttc agagcgcttg gggacagaac ttcctttctt tattaaaagt ggagtcacta
    51721 ttcctaaaaa aatcttactt atagatgata tctatactac aggagcaact ataaatcgtg
    51781 ttaagaaact gttggaagaa gctggtgcta aggatgtaaa aacattttcc cttgtaagat
    51841 gaggaaaaaa tttgcaaaaa tagaatgaaa gcgttataat aaaatcataa aaacaaaaat
    51901 gtttagaaag aaggtactca tatgattaaa tatagtatcc gtggtgaaaa cctagaagta
    51961 acagaagcaa ttcgtgatta tgtagtttct aaactcgaaa agatcgaaaa gtacttccaa
    52021 ccagaacaag agttggatgc ccgaattaac ttaaaagttt atcgtgaaaa aacggctaaa
    52081 gtggaagtaa cgattccgct tggatctatt actctccgcg cagaagatgt atctcaagat
    52141 atgtatggtt caattgacct tgtaactgat aaaattgaac gtcagattcg taaaaataaa
    52201 acaaaaatcg agcgtaaaaa taaaaataag gtagcaactg gtcaattatt tacagatgct
    52261 ttggtggaag attcaaatgt tgtccagtct aaagttgttc gttcaaaaca aattgattta
    52321 aaaccaatgg atttggaaga agcaattcta caaatggatt tattggggca tgatttcttt
    52381 atctatgtag atgttgaaga tcagacaacc aatgtgattt atcgtcgtga ggatggtgaa
    52441 attggtttgt tagaggttaa agaatcttaa tttcaatatg tgtaaaggta ggtttactga
    52501 attgtaaact acctttttct tataattgat agaattactg attacacttt taaaaagtcg
    52561 ctttttgagg ggtattatgg tataatgggt gccaagaggt tttgaatgaa aaaattttat
    52621 gtaagtccaa tttttcctat tctagtagga ttgattgcgt ttggagtctt atccactttc
    52681 attatttttg ttaataataa tctgttgacg gttttaattt tgtttctttt tgtaggaggc
    52741 tatgtttttt tatttaagaa actgagagtg cattatacaa ggagtgatgt agaacagata
    52801 cagtatgtaa accaccaagc ggaagaaagt ttgacatctc tattggaaca gatgcctgta
    52861 ggtgttatga aattgaattt atcttctgga gaggttgagt ggtttaatcc ctatgctgaa
    52921 ttgattttga ccaaggaaga tggtgatttt gatttggaag ctgttcaaac gattatcaag
    52981 gcttcagtag gaaatccgtc tacttatgcc aagcttggtg agaagcgtta tgctgttcat
    53041 atggatgctt cttcaggtgt tttgtatttt gtagatgtat ccagggaaca agccataaca
    53101 gatgaattgg taacaagtcg accagtgatt gggattgtct ctgtggataa ttatgatgat
    53161 ttggaggatg caacttctga gtcagatatt agtcaaatca atagttttgt agctaatttt
    53221 atatcagagt tttcagaaaa atacatgatg ttttctcgtc gggtaagtat ggatcgattt
    53281 tatctattta ctgactacac ggtgcttgag ggcttgatga atgataaatt ttctgttatt
    53341 gatgctttca gagaagagtc gaaacagaga cagttgccct tgaccttaag tatgggattt
    53401 tcttatggcg atggaaatca tgatgagata gggaaagttg ctttgctcaa tttgaacttg
    53461 gctgaagtac gtggtggcga ccaggtggtt gttaaggaaa acgacgaaac gaaaaatcca
    53521 gtttattttg gtggtgggtc tgctgcttca atcaagcgta cacggactcg tacgcgcgct
    53581 atgatgacag ctatttcaga taagattcgg agtgtagatc aggtttttgt agtcggtcac
    53641 aaaaatttag acatggatgc tttgggctct gctgtaggta tgcagttgtt cgccagcaat
    53701 gtgattgaaa atagctatgc tctttatgat gaagaacaaa tgtctccaga tattgaacga
    53761 gctgtttcat tcatagaaaa agaaggagtt acgaagttgt tgtctgttaa ggatgcaatg
    53821 gggatggtga ccaatcgttc tttgttgatt cttgtagacc attcaaagac agccttaaca
    53881 ttatcaaaag aattttatga tttatttacc caaaccattg ttattgacca ccatagaagg
    53941 gatcaggatt ttccagataa tgcggtcatt acttatatcg aaagtggtgc aagtagtgcc
    54001 agtgagttgg taacggaatt gattcagttc cagaattcta agaaaaatcg tttgagtcgt
    54061 atgcaagcaa gtgttttgat ggctggtatg atgttggata ctaaaaattt cacctcgcga
    54121 gtaactagtc ggacatttga tgttgctagc tatctcagaa cgcgcggaag tgatagtatt
    54181 gctatccagg aaatcgctgc gacagatttt gaagaatatc gtgaggtcaa tgaacttatt
    54241 ttacaggggc gtaaattagg ttcagatgta ctaatagcag aggctaagga cacgaaatgc
    54301 tatgatacag ttgttattag taaggcagca gatgccatgt tagccatgtc aggtattgaa
    54361 gcgagttttg ttcttgcgaa gaatatacaa ggatttatct ctatctcagc tcgaagtcgt
    54421 agtaaactga atgtacaacg gattatggaa gagttaggcg gtggaggcca ctttaatttg
    54481 gcagcagctc aaattaaaga tgtaaccttg tcagaagcag gtgaaaaact gacagaaatt
    54541 gtattaaatg aaataaagga aaaggagaaa gaagaatgaa agtaatcttt ttagcagatg
    54601 ttaaaggaaa aggtaaaaaa ggcgaaatta aggaagtacc aacagggtat gcgcaaaact
    54661 ttcttatcaa aaagaatcta gccaaagaag cgactgctca agctgtaggt gaacttcgtg
    54721 gtaaacaaaa atcggaagaa aaagctcacg ctgagatgat tgcagaagga aaagcaatta
    54781 aagcacaact tgaagcagaa gaaactgttg tagaatttgt tgaaaaagtt ggtccagatg
    54841 gtcgtacctt tggttctatt accaataaga agattgcaga agaattgcaa aagcaatttg
    54901 gaattaagat tgataaacgt catattcaag tacaagctcc gattcgagcg gttggtttga
    54961 ttgatgtgcc agtgaaaatc tatcaagata tcacaagtgt aatcaatctt cgtgtgaaag
    55021 aaggataagt ttacactttc ttgacaagat tgtaaaagga agggaagtct gatggcagaa
    55081 gtagaagagt tacgagtaca acctcaagat atcttagctg agcaatccgt tttaggggct
    55141 atctttattg atgagagtaa acttgttttt gtgcgagaat acattgagtc tcgggacttt
    55201 tttaagtatg cccatcgttt gattttccaa gccatggtcg atttatccga tcgtggtgat
    55261 gccatagatg caacaacggt tcgtactatc cttgataatc aaggtgattt acagaatatt
    55321 ggtggcttgt cttacttggt tgagattgtt aattctgtgc caacttctgc taatgcggag
    55381 tattatgcta agattgttgc agaaaaagca atgctacgtc gtttaattgc caagttgaca
    55441 gagtctgtca accaagctta cgaagcgtca caaccagctg atgaaattat tgctcaggca
    55501 gaaaaagggt tgattgatgt cagtgaaaat gcaaatcgaa gcgggtttaa gaacattcga
    55561 gatgtgttga atctcaactt tggaaatctg gaagctcgct cgcaacaaac gaccgatatt
    55621 acaggtattg cgacaggtta tcgtgatttg gatcatatga caacaggact tcatgaggag
    55681 gagttgatta tcttagcagc tcgtccagca gttggtaaga cagcatttgc cttgaatatc
    55741 gctcagaaca ttgggactaa gttggacaaa acggttgcta ttttttcact cgaaatgggt
    55801 gcggaaagct tggtagatcg tatgttagct gcagaaggct tggtggagtc acattctatc
    55861 cgtacagggc aattgacaga tgaggagtgg caaaaatata ctattgctca gggtaatcta
    55921 gctaacgcca gtatctatat cgatgatacg ccaggtattc ggattacaga gattcgttct
    55981 cgttctcgta aattggctca agaaactgga aatcttggtt tgattttgat agactatttg
    56041 caacttatca cgggaactgg tcgagaaaat cgtcaacaag aagtttctga aatttctcgt
    56101 cagttgaaaa tactagccaa ggaattgaag gttccagtaa tcgctctgag tcagctttct
    56161 cgtggtgtag aacaacgtca ggacaagaga ccggtcttgt ctgatattcg tgaatctggg
    56221 tctattgagc aggacgctga tatcgtagct tttctctatc gcgatgacta ctatgaacgt
    56281 ggtggtgaag aagaggaggg tatcccaaat aataaggtgg aagttattat cgagaaaaac
    56341 cgtagtggag ctcgtggaac agtggaattg attttccaaa aagaatacaa taaattttca
    56401 agtatctcaa agagggaggc ataagatgtc agatgcattt acagatgtag ccaagatgaa
    56461 aaaaatcaaa gaagaaatca aggcacatga gggacaagtc gtagaaatga ctttggagaa
    56521 tggtcgtaag cgccaaaaaa atagattggg taagctaatt gaagtttatc catccctatt
    56581 tattgtggag tttggggatg tggaaggaga taaacaagtt aatgtttacg ttgaatcctt
    56641 tacttactca gatattctta cagaaaagaa tttgattcat tatcttgact aaagtgagaa
    56701 attttctcac tttttctttt ttctccgaat aatttaggtg aaggcaatca tcgctttata
    56761 ttatttttca aggaggaaga atgaaaattt taccgtttat agcaagagga acaagttatt
    56821 acttgaagat gtcagttaaa aagcttgttc cttttttagt agtaggattg atgctagcag
    56881 ctggtgatag tgtctatgcc tattccagag gaaatggatc gattgcgcgt ggggatgatt
    56941 atcctgctta ttataaaaat gggagccagg agattgatca gtggcgcatg tattctcgtc
    57001 agtgtacttc ttttgtagcc tttcgtttga gtaatgtcaa tggttttgaa attccggcag
    57061 cttatggaaa tgcgaatgaa tggggacatc gtgctcgtcg ggaaggttat cgtgtagata
    57121 atacaccgac gattggttcc attacttggt ctactgcagg aacttatggt catgttgcct
    57181 gggtgtcaaa tgtaatggga gatcagattg agattgagga atataactat ggttatacag
    57241 aatcctataa taaacgagtt ataaaagcaa acacgatgac aggatttatt catt
//
LOCUS       DAVLGK010000007        52143 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLGK010000007 DAVLGK010000000
VERSION     DAVLGK010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52143
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.007"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(264..626)
                     /locus_tag="VXE01_000483"
     CDS             complement(264..626)
                     /locus_tag="VXE01_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV0749457.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            640..714
                     /locus_tag="VXE01_000484"
                     /pseudo
     CDS             640..714
                     /locus_tag="VXE01_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(962..1099)
                     /locus_tag="VXE01_000485"
                     /pseudo
     CDS             complement(962..1099)
                     /locus_tag="VXE01_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1477..2166)
                     /gene="rplA"
                     /locus_tag="VXE01_000486"
     CDS             complement(1477..2166)
                     /gene="rplA"
                     /locus_tag="VXE01_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV0749458.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2374..2799)
                     /gene="rplK"
                     /locus_tag="VXE01_000487"
     CDS             complement(2374..2799)
                     /gene="rplK"
                     /locus_tag="VXE01_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV0749459.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2931..3068
                     /locus_tag="VXE01_000488"
     CDS             2931..3068
                     /locus_tag="VXE01_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749460.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEIADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            complement(3108..3824)
                     /locus_tag="VXE01_000489"
     CDS             complement(3108..3824)
                     /locus_tag="VXE01_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV0749461.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKPKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVVNKGDYYSIQGKYDEIVIANKHYPLSKDYNPGENPTAKAELLKLI
                     AAMQAAGYPISDHYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3842..4303)
                     /locus_tag="VXE01_000490"
     CDS             complement(3842..4303)
                     /locus_tag="VXE01_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0749462.1"
                     /translation="MCLICQRIELIKAGENPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KEHVTELHHMENPVKFRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     TGDMKGHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKHLA"
     gene            complement(4305..5342)
                     /locus_tag="VXE01_000491"
     CDS             complement(4305..5342)
                     /locus_tag="VXE01_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV0749463.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEEHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGKTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDEKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEERIDLPMTTHFAFSVFEE
                     VGHGANSNIPKEVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATELM
                     VDAYLKSEGVS"
     gene            complement(5440..6765)
                     /gene="brnQ"
                     /locus_tag="VXE01_000492"
     CDS             complement(5440..6765)
                     /gene="brnQ"
                     /locus_tag="VXE01_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV0749464.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6936..7028)
                     /locus_tag="VXE01_000493"
     CDS             complement(6936..7028)
                     /locus_tag="VXE01_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0749465.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(7071..7223)
                     /locus_tag="VXE01_000494"
     CDS             complement(7071..7223)
                     /locus_tag="VXE01_000494"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0749466.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(7383..7961)
                     /locus_tag="VXE01_000495"
     CDS             complement(7383..7961)
                     /locus_tag="VXE01_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV0749467.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(8015..9415)
                     /gene="pepV"
                     /locus_tag="VXE01_000496"
     CDS             complement(8015..9415)
                     /gene="pepV"
                     /locus_tag="VXE01_000496"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV0749468.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSSWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9428..10033)
                     /locus_tag="VXE01_000497"
     CDS             complement(9428..10033)
                     /locus_tag="VXE01_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV0749469.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            10204..11004
                     /locus_tag="VXE01_000498"
     CDS             10204..11004
                     /locus_tag="VXE01_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0749470.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNTLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11186..12019)
                     /locus_tag="VXE01_000499"
     CDS             complement(11186..12019)
                     /locus_tag="VXE01_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0749471.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKDQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGEYGLEHPQEIQLMRMTQFLMERMDPE
                     TIVWLRSLPLLEKKEVDGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(12009..13853)
                     /gene="uvrC"
                     /locus_tag="VXE01_000500"
     CDS             complement(12009..13853)
                     /gene="uvrC"
                     /locus_tag="VXE01_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV0749472.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNSPSKVCF
                     YYHIGQCMAHTICKKDEVYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDQEAVQALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQRDGLTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVELSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(13917..14594)
                     /locus_tag="VXE01_000501"
     CDS             complement(13917..14594)
                     /locus_tag="VXE01_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV0749473.1"
                     /translation="MRWLFRLIGAFFFFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANL"
     gene            complement(14673..15905)
                     /gene="murN"
                     /locus_tag="VXE01_000502"
     CDS             complement(14673..15905)
                     /gene="murN"
                     /locus_tag="VXE01_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV0749474.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTIGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15910..17130)
                     /gene="murM"
                     /locus_tag="VXE01_000503"
     CDS             complement(15910..17130)
                     /gene="murM"
                     /locus_tag="VXE01_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV0749475.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17242..18021)
                     /locus_tag="VXE01_000504"
     CDS             complement(17242..18021)
                     /locus_tag="VXE01_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0749476.1"
                     /translation="MAVMKIEYYSQVLDMEWGMNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(18090..19751)
                     /locus_tag="VXE01_000505"
     CDS             complement(18090..19751)
                     /locus_tag="VXE01_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0749477.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19926..22148)
                     /gene="recJ"
                     /locus_tag="VXE01_000506"
     CDS             complement(19926..22148)
                     /gene="recJ"
                     /locus_tag="VXE01_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV0749478.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIAFMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22425..23183
                     /locus_tag="VXE01_000507"
     CDS             22425..23183
                     /locus_tag="VXE01_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0749479.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNIYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            23223..23987
                     /locus_tag="VXE01_000508"
     CDS             23223..23987
                     /locus_tag="VXE01_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0749480.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDHSILSGYTSKRTALLDDSFKPSDYSIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            24000..24677
                     /locus_tag="VXE01_000509"
     CDS             24000..24677
                     /locus_tag="VXE01_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0749481.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24687..25346
                     /locus_tag="VXE01_000510"
     CDS             24687..25346
                     /locus_tag="VXE01_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0749482.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25595..26785
                     /locus_tag="VXE01_000511"
     CDS             25595..26785
                     /locus_tag="VXE01_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV0749483.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKKVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27106..27987)
                     /locus_tag="VXE01_000512"
     CDS             complement(27106..27987)
                     /locus_tag="VXE01_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV0749484.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28128..29456)
                     /gene="vncS"
                     /locus_tag="VXE01_000513"
     CDS             complement(28128..29456)
                     /gene="vncS"
                     /locus_tag="VXE01_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV0749485.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKYYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29453..30109)
                     /gene="vncR"
                     /locus_tag="VXE01_000514"
     CDS             complement(29453..30109)
                     /gene="vncR"
                     /locus_tag="VXE01_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV0749486.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDSVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30158..30241)
                     /gene="pep27"
                     /locus_tag="VXE01_000515"
     CDS             complement(30158..30241)
                     /gene="pep27"
                     /locus_tag="VXE01_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV0749487.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(30421..31800)
                     /gene="vex3"
                     /locus_tag="VXE01_000516"
     CDS             complement(30421..31800)
                     /gene="vex3"
                     /locus_tag="VXE01_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV0749488.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31852..32499)
                     /gene="vex2"
                     /locus_tag="VXE01_000517"
     CDS             complement(31852..32499)
                     /gene="vex2"
                     /locus_tag="VXE01_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV0749489.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32512..33789)
                     /locus_tag="VXE01_000518"
     CDS             complement(32512..33789)
                     /locus_tag="VXE01_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0749490.1"
                     /translation="MNPIQRAWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGSGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(34146..34316)
                     /locus_tag="VXE01_000519"
                     /pseudo
     CDS             complement(34146..34316)
                     /locus_tag="VXE01_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(34459..35058)
                     /locus_tag="VXE01_000520"
     CDS             complement(34459..35058)
                     /locus_tag="VXE01_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749491.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNYP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(35195..36079)
                     /locus_tag="VXE01_000521"
     CDS             complement(35195..36079)
                     /locus_tag="VXE01_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV0749492.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(36083..36469)
                     /locus_tag="VXE01_000522"
     CDS             complement(36083..36469)
                     /locus_tag="VXE01_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV0749493.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(36462..37805)
                     /locus_tag="VXE01_000523"
     CDS             complement(36462..37805)
                     /locus_tag="VXE01_000523"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV0749494.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(37892..38776)
                     /locus_tag="VXE01_000524"
     CDS             complement(37892..38776)
                     /locus_tag="VXE01_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0749495.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(38788..39405)
                     /gene="cysE"
                     /locus_tag="VXE01_000525"
     CDS             complement(38788..39405)
                     /gene="cysE"
                     /locus_tag="VXE01_000525"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV0749496.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHSFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(39421..41634)
                     /gene="pnp"
                     /locus_tag="VXE01_000526"
     CDS             complement(39421..41634)
                     /gene="pnp"
                     /locus_tag="VXE01_000526"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV0749497.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(42319..43185)
                     /gene="metF"
                     /locus_tag="VXE01_000527"
     CDS             complement(42319..43185)
                     /gene="metF"
                     /locus_tag="VXE01_000527"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV0749498.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQYMQELAPHFISITAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(43249..45498)
                     /gene="metE"
                     /locus_tag="VXE01_000528"
     CDS             complement(43249..45498)
                     /gene="metE"
                     /locus_tag="VXE01_000528"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV0749499.1"
                     /translation="MSTTIVGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATCIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGFDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDTDYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(45759..46025)
                     /locus_tag="VXE01_000529"
     CDS             complement(45759..46025)
                     /locus_tag="VXE01_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0749500.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVPLEQGKS"
     gene            complement(46151..46554)
                     /locus_tag="VXE01_000530"
                     /pseudo
     CDS             complement(46151..46554)
                     /locus_tag="VXE01_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            46710..47711
                     /locus_tag="VXE01_000531"
     CDS             46710..47711
                     /locus_tag="VXE01_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0749501.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(47779..50181)
                     /locus_tag="VXE01_000532"
     CDS             complement(47779..50181)
                     /locus_tag="VXE01_000532"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV0749502.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(50258..50767)
                     /locus_tag="VXE01_000533"
     CDS             complement(50258..50767)
                     /locus_tag="VXE01_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0749503.1"
                     /translation="MIIKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(50767..51813)
                     /gene="pheS"
                     /locus_tag="VXE01_000534"
     CDS             complement(50767..51813)
                     /gene="pheS"
                     /locus_tag="VXE01_000534"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV0749504.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNICKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
BASE COUNT        14731 a        11843 c         9827 g        15742 t
ORIGIN      
        1 agcaattgtt tcgtactatt ttagattcag tctactatac ataaactaac ctcctcatta
       61 ttagcaagga ttctactgat tataacctaa ttcttagact acttcaagac taactgtcca
      121 ataataatct acagataaat catccactct taataaaatt ttattcaatc catctactca
      181 ttcccaaaag gttgctgtat aatgcaagac atttttctta ctgattttac ttttccttac
      241 cctcaattta gtgagctaat aaattattct tcttcaaaag gttgagattt atctagtaac
      301 tctaaaacat taatggtagg tagcaacatt gcttcactgc tatcaattgc cgaaactatt
      361 gaaacaatag aacgtaaata atgataaaga atagcagtac catttacgta tagaatatcg
      421 gtgatatttt catctatatt tatttcaaaa tatcctatta cagttacaga tatttttttc
      481 atggcatctt tgtcaactaa agaaacacta agttttacgg ctccatgact ataatcatct
      541 gtatgaccaa ccttaactat gggatataat atatcgaagg taaatgtgaa caaactgatt
      601 aggaaattta aaccaacttc taacaatctg ttatactcaa tgaaaaccaa agagcaaact
      661 aggaaactag cctcaggttg ctcaaaacac tgttttgagg ttgtagatgg aactgacgta
      721 gtcagctcaa aacactgttt tgaggttgtg gatagaactg acgaagtcag taaccatacg
      781 cacggcaagg cgacgttgac gtggtttgaa gagattttcg aagagtatta gaaagctcga
      841 tggactattc cagattcatt ccactagatt tcgaaatcga gtaggggata atctctagcc
      901 cctctcacac caccgtacgt gccgttcggc atacggcggt tcaactaact gttaacgcat
      961 gtcattcaag gtaataatcc aaacacgaaa ccagtccacg tttttcaagg actggttttg
     1021 atatagcacg tttaagtacc gacttctgag ctactaattg atagtggtcg ccccagccag
     1081 ataccttatc cgctatatag gccttattat cacgttcctg ttcgtagagc cacgatttcg
     1141 ctatcccttc ctctgacgat tcttatttcc agcgtcagac ttaaaacggt ctatccccag
     1201 accgttttaa tccgctacct cacgatagtc agacttggga atcgctattg ggttcaccgg
     1261 tagcaggtgc ccaccgagga cttacacctc aaatatataa taaaatgaaa taagaatagg
     1321 acgaatcgat caggacagtc aaatcaattt ctaacaatgt tttagaagta gatgtgtact
     1381 attctagttt caatctatta tacaacatgc ccgtcgtaca tcaaaaaaag ttgagacata
     1441 gcgtcttcaa cttttttaca ttactttaac tactgattaa agtgagttta cgtcaacttt
     1501 gataccaaca ccttgagtag ttgtgatagt caagtttgtt acgtaagttc ctttagctgt
     1561 agctggtttt gctttttgga ttgtttcgtt gaaagcttta aagttttcaa ccaatttttc
     1621 agcttcaaat gatactttac cgatgattgc ttgaacgtta cctgcacggt cagcacggta
     1681 agtgatttta ccacctttag actcttcaac tgctttagca acatccattg ttacagtacc
     1741 agttttaggg tttggcatca agttacgtgg tccaaggaca cgtccaagac gtccaacaag
     1801 agccatcata tcaggtgtag cgataactac gtcgaagtcc aaccaaccgt cgttgatttt
     1861 agcaacaagg tcatcttcac caacaaagtc tgcaccagca gcttttgctt cttcagcttt
     1921 tgcaccacgt gcgaaaacaa gaacacgtga agttttacca gtaccgtttg gcaataccat
     1981 tgctccacgg atttgttggt cagctttttt aacgtcgatg ttcaagttgt aagcaacttc
     2041 tacagttgca tcaaattttg caaagttagt ttcttttgca agtgctacag cttcttctac
     2101 actgtatgct tttgtgctgt cgattttctc aagagcagca cgaagttgtt tgcttttttt
     2161 agccattttc tattctcctt gtaagtggtt caatcgattt tcatctccca cgtcacttct
     2221 cgaaatgatg aagtcttgcg ggttttcagt ctactatttt tctcttccta cggccttaag
     2281 ctcccttgct gtacccaagt acaagcctca gtcacttgcc tagtatgaaa agcaactaat
     2341 agactgctgt gagattttct actgtgttat tgattagtca acaacagtga atcccataga
     2401 acgagcagta ccttcgatca tacgcattgc agactctacg tttgctgcgt tcaaatctgg
     2461 catcttagtt tctgcaattt cttgtacttg tgcacgagta actgtagcaa ctttagtttt
     2521 attaggtgta cctgatcctt tttcaacacc tgcagctttt ttcaaaagaa cagcagctgg
     2581 tggtgttttc gtaacgaaag taaatgattt atcttcgtaa actgagataa caactggaat
     2641 gatcatacca gcttggtcag ctgtacgagc gttgaactct tttgtgaatc ccatgatgtt
     2701 gataccagct tgaccaagag caggtccaac cggtggagct ggtgtagctt taccagcagg
     2761 gatttgcaat tttacaagtt tttcgacttt tttagccatt tttaaatcct cctttgtggt
     2821 tttggcggta attagagatt tttacctccc acaagtatgt ttttcacata cccctccatt
     2881 atacactatt tatctggaat tgcaagagaa aagtttattt tttatactca atgaaaatca
     2941 aagagcaaac taggaagcta gccgcaggct gctcaaagta cagctttgag attgcagata
     3001 aaactgacga agtcagctca aaacactgtt ttgaggttgt gaatagaacc gacgcagtca
     3061 gtaggtaagg cgacgctgac gtggtttgaa gagattttcg aagagtatta atcgacgtag
     3121 tctccgcctt caaagccata gtactcttcc aaactgaggc cacttgcagc aatttctttg
     3181 gcttcttttc caacgtagcg gagatgccat tcttctgcca tgtagccggt ctccttttcc
     3241 ttgcctttga gatagcggac aacaaagcca tagtcagccg catggtccaa gagccactgg
     3301 gctgcctttt cttcagtaac taaatcacca tctgtcccaa taaggtcaaa agcaaggcct
     3361 gtttggtgtt cactataacc tgggcgtgct gagtagcgat ccgctgcttc cttaccatct
     3421 tgattgacat agtcttggta gagcttagcc tgagtttcat aacttctaaa accactgtag
     3481 tgatcgctga ttgggtagcc agctgcttgc attgctgcaa tgagtttcag caactctgcc
     3541 ttggctgttg gattttctcc tggattgtag tcttttgaca aaggatagtg cttattagct
     3601 atgacgattt catcgtattt cccttgaata ctatagtagt ctcccttatt gacaacttct
     3661 gcctttttct gactagatgc ttgagatttg ctacctacag ttccttccgg ttgactgctt
     3721 tgctccgtct tttgagtatt ttcttcaact ttcggttttt cttgcgaaca agctgcaaga
     3781 gtcaatgcta gtaaaccaga taaaatgaca tatctttttt tcatttcttt cttcctctct
     3841 cttaggccaa atgcttctcc aattcatgag ataagatttt aatcatctct tccagctctg
     3901 gcgattgtac ttggcaatct tctgctgcca tttcttccca gggcacccac cagactgggc
     3961 cacggccatt caatccatga cccttcatat cacctgttct tcgtggaaag agatgccaat
     4021 gagcgtgggc atcaccattt cctaggagtt caatattcat cttttcagcc tcaaatgctt
     4081 tggcgactgc ttcttggacc aaactcattt cctctaaaaa gcgaaatttt acaggattct
     4141 ccatatggtg gagttctgta acatgctctt ttgctaaaaa taaggtatag cccttgaagt
     4201 attggtgatc cccaataacc acatagcctg tttctagttc tttaacaaag tagggatttt
     4261 ctccagcttt gatgagttcg attctctgac agattaagca cattctatga taccccctcg
     4321 ctcttaagat aagcatcaac cataagctca gtcgctacta ctgaatcgat gtgggtgcgc
     4381 tcataagagt gactggactc aataccagct ccaagaagtg catgcttgac ctccgcgcct
     4441 gctgacatcg ctgctgaagc atccgaaccg taaaatggat aaatgtcgag cttaaatgga
     4501 atatcttgct ccttcgccaa agctactaag tgttgacgga agtcatagtg ataaggacca
     4561 gaagcatcct tgacacagat agatactgtg tactcatccg tctgttggtc atcccccatt
     4621 gcacccatat cgacagccag gtactctacc acctcttttg gaatatttga attggcacca
     4681 tggcccacct cttcaaagac tgaaaaggca aaatgtgtcg tcatcggcaa gtcgattctc
     4741 tcttctttat aaactcgaag gagattgagc agaattgctg cgctgacttt gtcgtccaag
     4801 tgacgggact tgataaaacc agtctctgtc acgacagtac gtggatcaaa gctgataaaa
     4861 tcaccgacct cgatgcccaa ggcacgcgtt tctttttcat tggtcacttt ttcatccaaa
     4921 cgcacttcca tattgtcctg agtgcgttca gcagttcctg catctttgta gacatggcaa
     4981 gatgtctggt ggatgaggat cgttccagat accgttttac ctgtactagc tacatgaaca
     5041 gtacagtttt ctccctcaat catgttccaa ggaaaaccac cgatacggtc caatttgaga
     5101 cgaccatctg gcttgactgc acgcacaatg gctccaagtg tgtccacatg ggcagttaca
     5161 tagcgatgtt cttcgtcgtt ttgacctttg atggtcacat tgacaccgcc cttggctgtt
     5221 cgaacaggct ggtaaccaaa accttctaga gtcttgacta aataattcga aatttcacga
     5281 gtaaagcccg ttggcgatgc gatggctgtc agttctttga tatattctac tgtttgattc
     5341 atttcttcac ctctttcgct acctattata acacatttat catcggataa aaaaagaaaa
     5401 tcactcctgt agacttggct acaaaagtga tttaagtgat tattccattt caaaaacatc
     5461 gctttcttgc ttgtttggta gaaccaatga gagcaagatt ccaacaatgg ctggcaccaa
     5521 ccatgggaga gatgccttgg caaaaggaag aacgctaaca agatttgcaa gaaactcaac
     5581 cttaaacgag cttcctagta cgcttgcaat ggcaataact gtaaccacag caattgtcaa
     5641 ctgcatacct ggttttgaaa gggcaacaaa tttgttgaca atgacaatca taacgatagc
     5701 aatcgtgatt gggtacaaga taaccagtac tggaattgag tacttgataa tcgcatcaag
     5761 acccaaattg gcaatagcaa atccaatcaa ggtaaaggct gtcgcataaa ccttgtagct
     5821 gatttgtggg aagcgctcat taaagaactc agctgttgac acaatcaaac caacagtcgt
     5881 tgtgaagcag gttacggtaa ccatagctgc aaggaagagt tgagctgttg agccaaagat
     5941 ttcttgagtg gcttgtgaca agatgtaaac acctggtgtt ccacccttca tcgcttcagc
     6001 tggtactggg aaatgatttc caagaaaacc taaaccgatg taaagagcgc tgaaggcaag
     6061 ggcaacaacg ataccaacaa cccaaatagt tgaaatgtat tctttcttac ttgaaaatcc
     6121 aagttgtttc aaggtttgaa ctgcgattac gctaaaggcc actgaggcaa gggcgtccaa
     6181 ggtattgtaa ccttctagga aacctgtacc aaaggcagaa gcttgataag cagctgaagc
     6241 agcttgagga cttgttccac catatttgat agctcccaga acgaccaaga taacaatcaa
     6301 aattgcaaag actggcgtta aaatacgtcc aatgcggtct aagatttttg atggattaag
     6361 cgaaatcaaa taggctgccg caaaatacag aaccgtaaat acaatcaagc caagtccttt
     6421 atttgcatcc gacaaaaggg ggctaatccc tacttcgtaa gctgttgtag cagtacgtgg
     6481 ggtagcaaag aatggaccga ttgacaagta aagaactgag aggtaaagag tcgcaaacca
     6541 aggcgctatc ttcgttgaaa tctcgtagat atatccttta ggatttagcg ttccaataat
     6601 aagggtcaag acggcgatac caacgcctga aaagacaaaa cctgcgatgg caggaagaaa
     6661 atgttctcca gatagagcac ctagagaagg cggaaaaatc aagttccccg caccaaaaaa
     6721 tattccaaac aggagcaaac ctgttagggt acctttttta gccataaaaa tctccttcat
     6781 atttataaaa tactgaccta gtataccacg attaggagtc tgaaaaaagc atcacgaggc
     6841 aaatattaaa tgttttcaat tttcttaaaa ataagaatta tctaaaaata aaactctcct
     6901 acccagtcca caccaagtag gagaaatgca aaattttaaa gttcttcaaa ggctaacatg
     6961 ccaccctgga cattgataac attataacct tgttctaaca ggaattggca agcacgcgcc
     7021 gatctcattc cagatttgca aataatataa tgcaagcgat ctttgtccaa ttaatcataa
     7081 ctatcagcca attgactaag cggtaggttg tgggcacctt ctaaatgaag agctgcaaac
     7141 tcatccactt ctctcacatc cactagagaa agctggtcgt tttggtaaag ctggtaaaat
     7201 gcgtcaaagg ctatttcttt cattcttttt cttctaatac tcttcgaaaa tctcttcaaa
     7261 ccacgtcagc gtcgccttac cgtgcgtatg ttaccgactt cgtcagtttt atctgcaacc
     7321 tcaaagctgt actttgagca gcctacgact agcttcctag tttgctcttt gattttcatt
     7381 gactataaaa tggttttaat tctttttttc aaatctggca ctacttctgc ctcaaaccaa
     7441 ggatttttgg ccatccagat ttgatttcgt ggtgatgggt gaactagcgg aaaataggct
     7501 ggcagatagt ctttatagtg tttcaccctc tccgttacct tcccactgat tttctcctgt
     7561 aaatagtagg cttgggcata ttgcccaatc aagagggtta actgaatatc aggcaattcc
     7621 tgtaagagct gcggatgcca tttttctgca aaacctgtac gaggcggaag atcacccgac
     7681 ttgccatgtc ctggaaagta gaaatccata ggcaaaacag caaaataacc tgaattgtaa
     7741 aaggtatctt catccacacc tagccagtcc cgcaagcggt caccactttt atctttccag
     7801 taaaggcctg cttcttgagt tttaagtcct ggagcctgac cgatgatatt gatgcgagca
     7861 gtttttggcg ctgcaaagag aggctcaatg ccacgctctg tatagctggc attctgtgaa
     7921 tccgccatga tagcctgttt gattctttcg atttgagaca tctactttcc ctccaaaaag
     7981 aagtccaagc ataagatctc agacttctat cgttttattt gatcaattcg taaatagctt
     8041 cggcataaat tgctgctgct cggaagagat cgtccaaggc aataaattca ttggcttggt
     8101 gcatggtatc aattgagtct gggaacatag caccataggc aactccgcgc tctaacaagc
     8161 gaccaaaggt tccaccaccg atgacttgtt catgaccttt aaggcctgtt tgtttttcat
     8221 agacattcaa caaggtttgc acaagtggat cttccattgg cacatagtga ggggtatgac
     8281 catgttctga tagactgaca gaagcaactg gcaagttttc taggattgac ttgatttgtt
     8341 ctggacttgt tccttttgga tagcggatgt taagggcaat ggtattatca gcacttgttt
     8401 catcgaagcg gaagacgccg gcattcatag aaagagcacc catcttttca tccacatgag
     8461 caatcttgag attttcaccc tcatgatcgt tcaagagaat tttacctgcg atgtcaaggt
     8521 agtctttggc tggaccagca aagccaaact ggctgaggaa gagggctagg taagtcgcac
     8581 cattgacacc tgaagcaggc atagcaccgt gggctgattt accaatgatc gtcaccttgt
     8641 atttgccagc ttcttcttgg agttctcctc taagtttgtg ttctgcaaca aaggcatcta
     8701 gtttagcttg caagtcagcc aaatcacctg aaacgactgc tgttgctgat tctggtacca
     8761 tattttcacg taaaccacct gtaaagctgt gaagacgggc agcacctgta ttttctcctg
     8821 caaagtggag gtattccgtg atatttcctt tttcaccatt gatgattgga aattcagcat
     8881 ctggtgagaa accgaaatct ggtttggcaa gtcctacgtg ctcaaagtag tagtccatgt
     8941 ctgcccagcc tgattcttcg tctgttccaa cgatgaagcg aactttctta gaagttggaa
     9001 gacccaattc tttgatgatt ttcaaaccat agtaacaagc tgttgtagga cccttatcgt
     9061 ccgaagcccc gcgcgcataa aggcgaccat ctttgatagt tggtgtgtaa ggatctgtat
     9121 cccaactgct accagctgga accacgtcca tatgggcaaa gattccgaga acttcttctc
     9181 catcaccaaa ctcaaaatgt cctgcatagt tatcaacatt tttagttgga taaccatcac
     9241 ggtctgcgat ttcaaggaat ttttccaagg cttttactgg accaggtcca aatggatgtt
     9301 gggcatcagc cttgctatca tcacgttctg agttgatttc caaaaggcta aacaagtcag
     9361 ccaagaggtc ttctttgcgt ttttctactt ctgctgtaaa atcaattgct atcatttttt
     9421 cttcttccta tcttttttcg atgatttcat ctactggcaa gcggtagctt ggttccaatt
     9481 tgtcgtctgt gtaacccact gtgatcaaga gttctgggcg gaaacggtct tcgatttcca
     9541 aaacttcatt aacttttgat ttgtcaaaac caagaataat gttagaacca attccttggt
     9601 ctgtaagagc aagaaccaag ttcatggcaa ccaaacctgc attgagagct aggtagtcgc
     9661 tgacttgttg ttcattgtag cgtgcaaatt cagctggcaa atttttcatg aagtattgaa
     9721 gttgttcttc tgagaaattg ttagcaccac caactcgggc aatcttacga gcgcgtttgg
     9781 caaggtctgt atctgtaaat agggcaatgg ttacaggtgc tgatgatacc tgctcaaagt
     9841 ttgaaccata agccaacttt gccagttcag catttttctc acgaacaact acaaatttcc
     9901 aaggctggct gttgtgggcg cttggcgcca aggttgcaat ttcgatagcc gtacgcacat
     9961 cttttggatc aacaggctta tcagtgaaat gcttggtcgc atgacgtttt ttatttaatt
    10021 caagaaattt cataatcgat ttccttttct aattctactg cttccattct accataattt
    10081 gaaagagctt gcagggattt ttcatgatta agtttttcta tcacagacat aaaagatata
    10141 tattggttta tcaggaacat ttctgataaa ctagcaagta ctttacattt gaatggagac
    10201 agtatgaaaa aatttagcct attactagct atcctaccat ttttggttgc ctgtgggaat
    10261 caagctacac ccaaagagac tagcgctcaa aagacaatcg tccttgctac agctggcgac
    10321 gtgccaccat ttgactacga agacaagggc aatctgacag gcttcgatat cgaagtttta
    10381 aaggcagtag atgaaaaact cagcgactac gagattcaat tccaaagaac tgcttgggag
    10441 agcatcttcc caggacttga ttctggtcac tatcaggctg cggccaataa cttgagttac
    10501 acaaaagagc gtgctgaaaa atacctttac tcgcttccaa tttccaacaa taccctcgtc
    10561 cttgtcagca acaagaaaaa tcctttgact tctcttgacc agatcgctgg taaaacaaca
    10621 caagaggata ccggaacttc taacgctcaa ttcatcaata actggaatca gaaacacact
    10681 gataatcccg ctacaattaa tttttctggt gaggatattg gtaaacgaat cctagacctt
    10741 gctaacggag agtttgattt cctagttttt gacaaggtat ccgttcaaaa gattatcaag
    10801 gaccgtggtt tagacctctc agtcgttgat ttaccttctg cagatagccc cagcaattat
    10861 atcattttct caagcgacca aaaagagttt aaagagcaat ttgataaagc gctcaaagaa
    10921 ctctatcaag acggaaccct tgaaaaactc agcaatacct atctaggtgg ttcttacctc
    10981 ccagatcaat ctcagttaca ataacactct tcgaaaatct cttcaaacca cgtcagcttt
    11041 atctgcaacc tcaaagctgt gctttgagca acctacggct agcttcctag tttgctcttt
    11101 gattttcatt gagtataaga tatactaaaa gcgattggac cagccaatcg cttttttagt
    11161 ttgcattggc tattttagga aactcttaca aaaaatcaaa aaaattcttc acatcctcta
    11221 catacccatg cttttctatt aagctggcta ataattccag attgtgcccc tgatagttat
    11281 cgtcacgacg cagttcttca tacatttcga taaagggaag ccccttggac ttggccaatt
    11341 ctaactcagc ttcgtaatca taagcaactt tacgaaattg gatattgagt aattccccat
    11401 cttcaacttc tatcacggca tactgggcac ggtgattttt taacgcctcc caattaaaat
    11461 agggcatgcc aatcgaccct ggattgatga tttgttgccc ttgacttcca taacgaagca
    11521 actgcttgtg aacatgacca tagacggcca cgtccgtttc cgcatctagc agttggtcaa
    11581 atttctctgt atcattctca actagcaagt caccaccata gttcttattt ggcaaattat
    11641 gagagataga aaagcgtagc ccgtcaactt ctttcttttc cagcaaaggc aagcttcgta
    11701 gccagacaat cgtttcagga tccattcgct ccatcaaaaa ctgggtcatt cgcatgagct
    11761 ggatttcttg cggatgttcc aaaccatatt cgccatccaa ggcctcaagg acacgatcat
    11821 cccaattgcc tcgaacactt gctgtgatag gaaggtcctt tagcagggcg accaagtcat
    11881 ttgcacctgg accgggaaga aaaatatctc ccagaagcca gtattcactg accccttgat
    11941 ctttagcatc tgcaatcact gcttctagcg ccgtcgcatt gccatgaata tctgataaaa
    12001 ttgcgatttt atggttcatt gtggtttcct tccgtttggt aatctactct ttcttctgct
    12061 acttgaggca aggcttctcc ctgagggttc aactttctct gaacagcttc tgctactgct
    12121 ctaggcacac caacttcgac aatttcatcc acactggctt ccttgatttt agttagagac
    12181 ttgaaatgct tcatgagatt ctgcttgcgt ttaggtccca gaccgtcaat tccatccagt
    12241 tgtgatgaaa aagaattttt ggagcgcagt tggcggtgaa aggtgatggc aaagcggtgg
    12301 acctcatctt ggatgcgttg gaggaggaaa aattcctgag aattgcgtga caactccact
    12361 acctcaagcg gatctccaaa gagcaattca tgggtttggt gcttgtcatt cttttgcaga
    12421 cctgcaatgg ggatatccaa gcccagttcc tcttggatga cttgcttagc gatattgact
    12481 tgaccttgtc ccccatcaat cacaatcaaa tctgggggag tcaaaccgtc tcgttgaact
    12541 ctaccataac gtctgcgaat gacctctcgc atactggcgt agtcatctgg acctacaacc
    12601 gtttttatct tgtacttacg gtaatccttc ttactcggtt taccattgac aaagaccacc
    12661 atggctgaaa cagggctagt tcccatgatg ttggagttgt caaaagactc aatgcgaact
    12721 ggagttggaa tttgtagaag tcgtcctagg ttttcaatag ccccttgggt cttttcgact
    12781 gatttttcta gcaggttaaa tttctgctcc agactaacac gggcattttt gatggctaga
    12841 ttgaccagct gttttttctc tccacgctgg ggtttgagaa tcttagtatc caccaaggcc
    12901 tgaacggctt cttgatcaat atcctgcgga atcagtacct cattgggaac taggtgagat
    12961 ttttcttgat agaattgtcc cacataggtc aagaaatcct catctggatc attgaagtag
    13021 gggaagagat tgacatcgcg ctcgatgagc ttgccctgac ggacaaagaa aacctgcaca
    13081 cacatccagc ccttatccac atagtagcca aagacatcgc gattttggag atccttagcc
    13141 atgacccgtt gcttggttcg aagcgttcca atagcctgaa tcaggtcacg gtattccgcc
    13201 gcacgttcaa actccatagt ctgggctgcc gctgccattt tgccctttag ctcatcaatg
    13261 attttgttat cctgcccttt cagaaaatca gaaacctcct gggccataga cttgaaataa
    13321 acctcatcct tcttacagat ggtgtgggcc atacattggc cgatatggta gtaaaaacag
    13381 accttagagg gcgagttggt acattttcga aaagggaaaa tcctatctag aagtcgcttg
    13441 atttcattgg ctgcccccac atctggataa gggccaaaat aaagaccacc gtcctttttg
    13501 acctgacgag taatgataag ccttggatag cgctcattgg tgattttgat gaaaggatag
    13561 gacttgtcat ccttgagcat gatattgtac ttgggcttgt tttccttgat caggttgatt
    13621 tctaggagaa gtgcctcaat attagactcc gtaacaataa attcaaaatc cacaatttca
    13681 gacaccagag cctctgtctt ggtatcatga cttccacgaa aataggaccg tactcgatta
    13741 cgcagatttt tagcctttcc tacatagata atggtgccat ttttatcctt atgaatgtag
    13801 caaccagggc tggtcggcaa gagctctagt tttgatttaa tcaagttgtt catagttcca
    13861 ttatagcaaa aaaagtaggg aaagatagta ccctactcac tagtctcata tatttttcag
    13921 aggtttgcaa catcctcttc ctggatacca taaaaggaac ctgctggttg catgacagac
    13981 ttctcatctg tatggtccaa gccaatcgca tgacctaact catgttctgc cgtatggaca
    14041 aggcgttcat aggagtagcc atagtatgga ttggacaaat aataatgatt caaccgcacc
    14101 gttacggaca agaattgccc tgttaagaga ttagtttgac tttccgcctc tcctgccaca
    14161 ggagtgcctc cgtcgttcat ctccgtagcc gtaatatccg ccttactaga ctcagtcacg
    14221 agttcaaagt taaaagcacc agtttgattc cagttctgga ttgcttctaa ataagcctct
    14281 tgaaagcgtg aatccatctg cggatccagg taaatacgag cagaggcctg tgcccacctt
    14341 ccttcagaat gctggtgact atctgtctgg cttaacttag gcagttgccc tgttttctcc
    14401 cattggtcaa tactttgttg accaattttt actgaccgtt ctgcttgctt tagcgctcct
    14461 tgaaaatccc cgttcagata ccagagaagt ccgaaagcaa gcacacataa gagcacaact
    14521 atccaaacca gacgccaaaa caaacgccac acaaaaaaaa agaaagcccc tatcaaacga
    14581 aaaagccagc gcatgtctct ccacctttct agcaaataag aattatttta ctaaaagaag
    14641 ctaaaagaaa tctaaatact gactttttca tcttaacgtc ctactatttt tttgagtaac
    14701 tggatagctt tgtattttaa aggcgatgga tggtaacgga aagtacccgc tttgcgtaca
    14761 atatagccat taaaattctg tttaaaacgc aaaacaccat cacttccatc aaaaatccct
    14821 tgaatgccta ggaaattgta tttaggtatt ccacgtttta tgctttccaa cataacatat
    14881 ttttgaagca gtgcaggggc atagaactta ttaaactcag tgtaggaacc actaaagaga
    14941 taagtcgttt cctgaggcat ataaacaaat aaactcccag ctaaaacaat atcttcttct
    15001 ccatattttt caatcaagtc tcgcgcttct gcttttcgaa cttcaaacgt ttcaaattga
    15061 ctagaatatt ctctcagttg attttgtttt ttctcagaat gaggattttt actcaaatca
    15121 agtcgcaact tgtccaagtt ttcttctagt ttactttgtt caccttgcaa tttgctcata
    15181 tagtccgaaa aatttaagct tgctatgaga aactccgctt gttctccaaa agtatcataa
    15241 aaatgctcat aatattctaa acttttatca ctatattctc tacgttcaga ggtttctttt
    15301 gttatattct taaaaatcga tagttcttca cgttttaact ttttcaaccg aatgccaaag
    15361 gtttcagcct ttttcaccaa gggtttaccc tttttgctaa aacttttaag caaactcttt
    15421 tcagttaatt cagttaaatc tttatagtat aaccaatctg gttctccacc tgggtaacct
    15481 attgttaagc catcaaattg ataacctaaa tcagtcaaac cttgaataat actttttttc
    15541 tcagcatcta ttggattacc ttggctatca aaagtttgat aagtttcata aggttttaca
    15601 agcaactcta atacaccatt ttgcttggca tattctttta actctgcata aaaaactgga
    15661 agagcatctt gttgggtata aatcggcccc gaattgagtt ccatatgcag accacccagc
    15721 atgggcaagc tataaaccag agctgcaact tgaatttctc cttcttgttt caaagcaaga
    15781 taaacaattc gagcccctct tttttctagc aaatccccca tctggacaga ttgcataaag
    15841 gaacgagaag aaacctgatc agaataagtc tgaaactctt ctttcgtgag tgttgttagt
    15901 gccatatact tactttctat gtttttttct taatgtttta cggaaatcaa gagcaagtct
    15961 taacagagga tagagaggat gagtgggcat tgtaaattca cccaagtatt cttcaatcgt
    16021 tggattaaat ttttccttaa aatgataaag tccaccattg agagagtttt caacaccacc
    16081 taaattttgc cagaccatac ctcgctcaaa ggcatagcga gccgtttcat accatgttaa
    16141 aattggtgca ttgtaacgtt taaaatcatc atccatacca gcatatatat tgacagaggt
    16201 agtaccaaat tccaaactca aagtagccgc taaaggaact ctcgcttgac ctacatctat
    16261 atattcctgc aagaaggtca attcctctaa caaacgttct ttttccttct tctgcgcttc
    16321 tacttttgaa gttcgagtcg actcagtaaa ggtctcttcc aaggctctat ttttcgctaa
    16381 ctgttcttct aactcttgcg aacgtttaga aacatccaag gtggccaagg tgatataggc
    16441 cttgtcctta aaattatcta acaatttttt ataataggct tcattcctca aatgaatctc
    16501 ttttcgcttc tcagtttttt tcatcaactc cgaaaatgaa tctaatagtt ccagtccacc
    16561 atattgaatc tcaagccctt tgtttcgtgc tgttcgaata gcctgttttg ttgacttgga
    16621 aagtttatct tcttcaaaat tttccttgta tattttcgcc tgaatacgag gttgaatggt
    16681 gtctcccatt tcctccgttt ttcctgacca ccttactccc atttgttgca aactatcaat
    16741 aatagccaga ttttcaggaa attctgtctt ttcctgattg attaaacttt gagataggca
    16801 aatacttggg tcaaaagtca caaaaaccgc tctcttactg cgagcatagg acttaataga
    16861 ctgaatggca aaattcaaga gttctttatc cccataatcc aatataggtc ctcttgggat
    16921 ataaaacatt ttatagccta gcggaagagt tctaatcaaa atactagctg tcgccagtaa
    16981 tttttcttcc ctgtaaacac caaacttctc atgttgccaa ttagacttaa cttcctccca
    17041 agcactactt tgtaatacat tggctaattc atgttctttg acaaactgat catattctaa
    17101 tgtgggaatg ccaatttgat aacggtacat ttcctactct ctttcctcca gtattttatt
    17161 actattctac tactttcgtt tgaaaagtct agtgaaaaca tattttattt tagttctact
    17221 ccccctatgc tgaagttcaa actaagtcag tctctcttct aatttgaaat caattggtag
    17281 agttgttaaa aaaacttcca attgtttttc ccagtagtac cactcgtgag ttccagcgct
    17341 atggctatag gtcacatcaa aacctagttt tttgagattt ttcactgcga gattattggc
    17401 ttcgtacaag aaatcctgtt cgccacacca cgcccaaagt ttggtctttt tatccgattt
    17461 tttagccaga ctttcaagag aatagggact agttgtccag tctctaatct ctccaaaaac
    17521 acctctccag taggctggac ttcccagatt ttgactttca ggagaaaagt tttgaaagct
    17581 gagggcacct gaaaaactag ctgcatgaga aaaacgattt gtcgcaagag ccagtttgaa
    17641 acagccgtag cctcccatag aaagaccagc tataaaggtc ttttcacgct tgctagtcat
    17701 attagggaag aagcgtttca gaacctgtgg caattcctct gctagagccg tgtagtagtc
    17761 aaaaccatac tgggtatcgg tgtaccaacc attgctggta ttgggcataa caacgatgag
    17821 attagttcct cgaagcaagc gttctacatt ggtccgctta agccaactat tatgatttcc
    17881 agacatcccg tgcaaaaggt acaagacggg aatatcttca cactctggtt cttccactcg
    17941 attggcatca gggtagagga cattcatccc ccactccata tccaatactt gtgagtaata
    18001 ctcgattttc attactgcca tgattttctc cttctatttt tctataagaa aaagccgaaa
    18061 ctcgactttc tctctgttta tttcaacgat tattttgctt ccatgactac tggtaaaata
    18121 gctggacgac gcttggtttg gtcaaagaga tacttggtca aattatctcg aaccttccct
    18181 ttaagatctg cccagtcaaa gtcatctcct tgaagataat cttctaccgt ttggttaatc
    18241 aattctgaac tttcacggag aatatcgcga ctcttcttga gataaacaaa tccacgcgtg
    18301 tgaacacgag ctctagccac aattttcttc tcacgacggt tgactgtaat agccacgatg
    18361 aaaattccat cctctgacaa gaccttacgg tcacgaagaa caacatttcc aacatcacca
    18421 atggcattcc catcaattaa gatatctcct gctgaaaccg atccagctgg aacaaagtct
    18481 ccattctcgt aagccatggt cgtccccttt ttaggaatga agatgcgttc tggcaacatc
    18541 ccaactgcca tggcagcctt agcgtgagca tccaactcac gatactcccc ttggacaggg
    18601 aagaggtact taggttgcaa aagattgatc atcagctgca aatcacgcac atttccgtgc
    18661 cctgatacat gtaaactttg ggtaatcaat ttgacaaccc cacctgcctg ataaatcata
    18721 ttttctacac gcgcaacaaa ggcttcttta gcaatagacg gagccgtagc aatatagacc
    18781 aggtccccat ccttgatttc tacataacga tggcgaccaa tcgacatctt acgaagtcca
    18841 ttgataggtt cacccatacg acctgtctca agaataatca actcatggtc ttcaaagcga
    18901 gacatatctt taggcttaat caagagaatt tcgttggcta aagacaactt cttaagacga
    18961 atcgctgtgc ggacgatatt ttcaatatca aatcctgtca agacgatacg tcgacctgtt
    19021 ttatccgcag cgtcaaaaat ctgctgaata cgagaaagat tactggaaac agctgcaacg
    19081 atgatacgac cttcccagtc agcaatagtt tgggtaattt catccctaac ttcactttca
    19141 ctagccacct gaatattgct gtctgcattg gccgaatcac tgaggagagc caggacgccg
    19201 tcacgaccaa tctctgccaa acgagcaaaa tcagttgcat aagattcact agccgtttgg
    19261 tcaaatttga agtcacctgt ataaacgatg cttccttccg atgtcttcaa gacaattccc
    19321 agactctctg gaacggagta agtcgtaggg aagaaggaaa ccactgtccc accaaaatca
    19381 atctccgtat tctcatcaat gacatggaaa tcattaaatt tcttaacggc atcatttcct
    19441 ttgacaaaga gctttgccaa ctcaatggtc aactcagacc caaatacagg aactttagcc
    19501 tctgccaaga gataaggtag agcaccaatc gcatccgcat gcccgtgggt caagaaaacc
    19561 ccagcaatac ggtcgctatt ttcaaaaagg taatccatgt ttggaatcac cacatcgacc
    19621 cctaattgtt cattttcagg atattttaac cctacattca aaacaaaaat ggactctcca
    19681 atttcagcaa tgtacatatt ttttccattc tcacgcacac caccaagtgt tgttaaactg
    19741 atattactca tttttcctcc aaaatcttag tttatcttga ttatagggca actctaccct
    19801 cttattctaa aagttctaat actttcagcc gaatcttttc ctaccattat accatttttt
    19861 tgatgatttt caaaatgaag gtctgttttc aaaaaagagt tgatttccca actctttcct
    19921 aacttctact ctttttccat caaaaaatca taaatttctt gcaccgtacc cagcgccatc
    19981 atttcttggt ctttaacggt ttgtttgaga ttttggtaaa tttgactttc tcctatctcc
    20041 cgctttggcg cctctttatt gactgtcatc acaccatctt ttatcgtcac aaagcctagt
    20101 tcttcaaata cttgaatcat cttgaccagc aagatttgtt gaatattaag atatgcagcc
    20161 aaatctttca gcttgtagcg aatatcaaac tctgggaact ggtaaatagt cttgtacaat
    20221 ttggcaaact gatctctagt cccataacct gtcagataat aggccttgtc aatatcattt
    20281 ttgaaataga cagcagagaa atgctgttcc tgaaaaatgg tcttcagctg agtaatatcc
    20341 tctggaatgt tttttacgac aatagcttca ctagccgcaa gatttggcag ttctccagga
    20401 aaatccaaga ctggaacacc ttctggcaag actgcatttt ttccacgaat gttaaaaagt
    20461 tgaacacctt ccactcgcgc atccaccatc atcaactgga gggcagtttg gccattccat
    20521 tggttgacag acaatttaac cgctaactct agattcttgg tttgagaaaa ctctgtcgcc
    20581 catctgcctt gaccaaaggc taccacttca aaactcgcct cacccttgga aattttcagc
    20641 tttagatggg cattacctgc ccccatagta cgagcacttt cgacctgaaa attcttgata
    20701 taaaaaatag gtttctgatt atccattcca aaaggagcta aacgttcaaa acttttgacc
    20761 gtttccaagc taagtgcctc caaatccaac tcttcatcta ggtttaactt attcttgcca
    20821 ccagcatctg cacctttttc acgaacataa tcttccaaaa cctgagataa atctgagagt
    20881 tgctcaactt ccagcgtcat acccgctgca cctgcatgac ctccaaaggc gataaagagg
    20941 tctcgatggg gatccagagc ttcaaaaata tcgaccgctt ccacactacg agcactgccc
    21001 ttggcacgac cgtcttctat attaagaaca atgactgtct gtcccaattc ttccaataaa
    21061 cgaccagcca cgattcctag aaccccagga ttccagcctt ccttggccaa gacctgaacc
    21121 ttcttctcag gatccaccat ggtcttggct tcttcataga tagactgaac gatttccttg
    21181 cgctcttcgt ttttctggtg aatcataaag gcaatctcat gcgcttcctc atcatcaaat
    21241 ccagtcaaca aatcaatggc aggattggga tcatccaagc gacccaaggc attcaaacga
    21301 ggagcaatct ggaaaccaac cgtttcttct gttacttcgt tggcagcaat cccagccatg
    21361 tccagcattt cttgcagacc aatgcgctgg gtatgaccca acatttccag accatattga
    21421 actaagatac gattttcatc cgtcagactc accatatctg caatagttcc aatagcgacc
    21481 aaatcaagca attccacttg cacttcttct aacagggcac aagccaactt gaaagcaact
    21541 ccacaaccag ccaaatattt aaaaggataa tccgcatctg gatgttcagg atggacaata
    21601 gcataagcat ctggcagggt ttcaggcatg gaatgatggt ctgtcacaat gacatctact
    21661 cccatagact gagccaatgc aatagcctca tgaccagcaa ccccattgtc caccgtcaca
    21721 atcaaggaaa ttccttcttg ctcgataaag tatttataaa cactagcatt agggccatag
    21781 ccatcggtaa aacgatttgg caggtaaact cggcactcag caccaagttg ttccaaactt
    21841 tccttcacaa tagaagccga agtcatgcca tccgcatcat agtctccata aacgagaata
    21901 ttttcccctt cttcaatagc ctgacgaatc cgctccactg ccttgtccat atcatggagc
    21961 agataagcat catgtaagtc ctccaaggaa ggttctaaaa acttcttcag actttcttgg
    22021 tcctgaatcc ctctctcaaa caataaccga gccacctcag gacccagtcc agccttcttg
    22081 gctatctttg taaaatccgc atcttctacc tgcagggcaa actgccattc ataagtaggt
    22141 gttatcaaaa agacatccac tctttctaag aattctattg cttcattata acatgattta
    22201 gacgttttct ctatccagat tgctttttta taacatttta tagtatattg aaactagaat
    22261 agtacacctc tacttctaaa atattgttag aaatcgattt gactgtcccg atcgatttgt
    22321 cctgttctta tttcactata gtgaattttt tcagatatgg tttgacaaga acattctttt
    22381 attgtagaat cgtgttataa aatctaacac aaaggagatc tctcatggct ttagtagaat
    22441 ttaaaaacgt cgaaaaatat tacggagact accacgcact ccgcaacatc aatctccgtt
    22501 ttgaaaaagg acaagttgtt gtcctgcttg gaccttctgg ctctgggaag tccactctta
    22561 tccgtacgat caatggttta gagactgttg acaaaggaag tctcctagtc aatgggcacc
    22621 aagttgctgg tgccagccag aaagatttgg tacctcttcg caaggaagtc ggcatggttt
    22681 ttcaacattt taacatttat ccacacaaaa ctgtgttaga aaacgtaaca cttgcaccca
    22741 ttaaagttct aggaattgat aaaaaagaag ctgaaaaaac cgcccaaaaa tatctggaat
    22801 ttgtaaatat gtgggacaag aaagattcct atcccgccat gctatctggt ggacaaaaac
    22861 agcggatcgc catcgctcgt ggtcttgcta tgcatccgga actcctcctc tttgatgaac
    22921 caacatctgc tcttgatcct gagactatcg gagatgttct agcagttatg cagaaactgg
    22981 cgcatgatgg gatgaacatg atcatcgtta cccacgaaat gggctttgct cgagaggttg
    23041 cggaccgcat tatctttatg gccgacggag aagttttagt agatacgaca gatgtcgata
    23101 acttttttga caatccaagc aaacctcgtg cccaacaatt cctcagcaaa attatcaacc
    23161 acgaaagtga caaagtcaaa taaggaggcg cctatgaaaa aaaattcttt ttatcagcat
    23221 tattgattag ccttttcggc cttgctgctg ccaaaccagt ccaggctgat actagtatcg
    23281 cagacattca aaaaagaggc gaactggttg tcggtgtcaa acaagacgtt cccaattttg
    23341 gttacaaaga tcccaagacc ggtacttatt ctggtatcga aaccgacttg gccaagatgg
    23401 tagctgatga actcaaggtc aagattcgct atgtgccggt tacagcacaa acccgcggcc
    23461 cccttctaga caatgaacag gtcgatatgg atatcgcgac ctttaccatc acggacgaac
    23521 gcaaaaaact ctacaacttt accagtccct actacacaga cgcttctgga tttttggtca
    23581 ataaatctgc caaaatcaaa aagattgagg acctaaacgg caaaaccatc ggagtcgccc
    23641 aaggttctat cacccaacgc ctgattactg aactgggtaa aaagaaaggt ctgaagttta
    23701 aattcgtcga acttggttcc tacccagaat tgattacttc cctgcacgct catcgtatcg
    23761 atgccttttc cgttgaccac tctattctat ctggctacac tagtaaacgg acagcactac
    23821 tagatgatag tttcaagcca tctgactaca gtattgttac caagaaatca aatacagagc
    23881 tcaacgacta tcttgataac ttggttacta aatggagcaa ggatggtagt ttgcagaaac
    23941 tttatgaccg ttacaagctc aaaccatcta gtcataccgc agattaagga ggatacccta
    24001 tgacagattt atcatcttgg acagcctatt ttcaggattt tggacaattt ttcaatggtt
    24061 tcctctttac tcttgcccta gcgattggat cctttatcct cgccatggtc ttaggaatct
    24121 tctttggtgc catgtcaacc agtaaacgtc caattttacg cattttagct cgcatcttcg
    24181 tggaatttta ccaaaacact cccctcttgg tgcagtttgt tattgttttt tatggcctac
    24241 ctcttatcag tgaccacatc atcatgattc caatttattg gacagccgtt ctctgcgtgg
    24301 gactctatca cggcgcttat atcgctgagg ttattcgttc agggattcag tctattccta
    24361 gtggtcagat ggaggccgcc ttgtcgcaag gttttaccta tatcagtgcc atgcgcttga
    24421 ttatcttgcc tcaggccttc cgcatcattc tccctccatt gaccaaccaa attgttaacc
    24481 tcatcaagaa cacatctact gtagctatca tctctggagt agacttgatg tttgtgacta
    24541 agtcttggtc ggctctcaac ggaaactata tcccagcctt tttaggtgct gctcttctct
    24601 actttgccct atgcttccct gttgcccagt ttggtcgcaa gatggagcaa gccaataaaa
    24661 aagcctattc actttaggag gttactatgg aatctatttt agaaatttta accccagata
    24721 acctagtctt tatctttaaa ggatttggct tgaccctcta tatttctctg attgccatca
    24781 tcctctctac tatcatcggt accgtgcttg ccgtcatgcg aaatggaaaa aatcctatct
    24841 tacgcattat ttccagtatt tatatcgagt ttgtgcgcaa cgttcccaac cttctctgga
    24901 tttttactat ctttttggtg ttcaaaatga aatccacacc agcaggtatt acagccttta
    24961 ctctctttac atcagcagcc ttggctgaga ttattcgagg cggtctcaat gccgtagaca
    25021 agggacaata cgaagcagga atgtcacaag gcttcacctc agcccaaatc ctctactaca
    25081 tcattctccc acaagccatc cgcaaaatgc taccagccat catttctcag tttgttaccg
    25141 tgattaagga taccagtctc ctctactctg ttatcgccct acaagaactc tttggagcca
    25201 gccaaattct catgggccgt tatttcgaac cagagcaggt cttcagtctt tacatcctga
    25261 ttgccctcat ctacttcagc tttaacctag cgatttctag cctgtctcat atgctagcca
    25321 aacgttggca acaagctgca gaataatact cttcgaaaat ctcttcaaac cacgtcagct
    25381 tcaccttgcc gtactcaagt acagcctgcg gctagcttcc tagtttgctc tttgattttc
    25441 attgagtata aacagccact ctccagttca attggagagt tttttgatga gagtagatat
    25501 ttatagacct caatttgaca ccatacattt tctatgataa aatgtaacaa attcatttac
    25561 aacaaatcga aatctaaatg aaatggaatt ttctatgaaa tcagtcaaag gactactctt
    25621 tatcatagct agttttatct tgactctttt gacttggatg aacacttctc cccaattcat
    25681 gattccagga ctagctttaa caagcctatc tctgactttt atcctagcca ctcgtctccc
    25741 actactagaa agctggtttc acggtttgga gaaggtctac accgtccaca aattcacagc
    25801 ctttctttca atcatcctac taatctttca taactttagt atgggcggtt tgtggggctc
    25861 tcgcttagct gctcagtttg gcaatcttgc catctatatc tttgccagca tcatccttgt
    25921 cgcctattta ggcaaataca tccaatacga agcttggcga tggattcacc gcctggttta
    25981 cctagcctat attttaggac tctttcacat ctacatgata atgggcaatc gtctccttac
    26041 atttaatctt ctaagttttc ttgttggtag ctatgccctt ttaggcttac tagctggttt
    26101 ttatatcatt tttctatatc aaaagatttc cttcccctat ctagggaaaa ttacccatct
    26161 caaacgctta aatcacgata ctagagaaat tcaaatccat cttagcagac ctttcaacta
    26221 tcaatcagga caatttgcct ttctaaagat tttccaagaa ggctttgaaa gtgctccgca
    26281 tcccttttct atctcaggag gtcatggtca aactctttac tttactgtta aaaattcagg
    26341 cgaccatacc aagaatatct atgataatct tcaagccggc agcaaagtaa ccctagacag
    26401 agcttacgga cacatgatca tagaagaagg acgagaaaat caggtttgga ttgctggagg
    26461 tattgggatc acccccttca tctcttacat ccgtgaacat cctattttag ataaacaggt
    26521 tcacttctac tatagcttcc gtggagatga aaatgcagtc tacctagatt tactccgtaa
    26581 ctatgctcag aaaaatccta attttgaact ccatctaatc gacagtacga aagacggcta
    26641 tcttaatttt gaacaaaaaa aagtgcccga acatgcaacc gtctatatgt gtggtcctat
    26701 ttctatgatg aaggcacttg ccaaacagat taagaaacaa aatccaaaaa cagagcttat
    26761 ttacgaagga ttcaagttca aataagtaat catactctcc tgggatttcc caggagagtt
    26821 ttttatagcc aaatgaaata agacctgaac gatggaattt tggcattcaa atcaattgat
    26881 aagaatattt tatagtggag tgaaatagga tacgaacaaa ttgattagga aaatcaaatg
    26941 aatttataga aatcttttag cagttatgtt gtcctattct agtttcaaaa cgctatagaa
    27001 gcagcattgt gctagtctag attcagttta ctatactaaa acgagtagct tgaaatcaaa
    27061 aaacccaccc tcacaggcag gttttatctg tattattcag ctagattatg ctttaccttc
    27121 tgaaccgaat acgtcgatac gttcttcaac tgatgcttgg atagctttta caccgtcagc
    27181 caagaattta cgtgggtcga agagtttttt cttgtcgtat tctgcttcgt ttgcttcgta
    27241 gtcacgagca aatttacgag ttgcgttagc gaatgcgatt tggcattctg tgttaacgtt
    27301 aactttggca acaccaagtt tgatagctgc ttggatttgc tcatcaggaa tacctgatcc
    27361 accgtgcaat acgattggga atcctggaag agcttctgtc aatttttgca agtggtcaag
    27421 gtcaagacct tcccagttta ctgggtaagg accgtggatg ttaccgatac cagctgccaa
    27481 gaagtcgata ccagtttcaa ccattgcttt agcgtcttcg attggagcca attcaccttt
    27541 accgatgatt ccgtcttctt caccaccgat agtaccaact tcagcttcta ctgagatacc
    27601 tttagcgtgt gctttttcaa caacttcttt agccaattta agattttctt caactggaag
    27661 gtgtgaaccg tcaaacatga ttgaagtata accaacttcg atacactcaa gtgcatcttc
    27721 gtagtgaccg tggtcaaggt ggatagctac tggtacagtg atacccattg attcaacaag
    27781 gttagcgatc aagttgcgag caactttgta accacccatg tatttagcag cacccattga
    27841 agtttggatc aaaactggag cttttttagc ttctgctgcg cgcaagatag cttgagtcca
    27901 ctcaaggttg tttgtgttaa atccaccaac tgcataaccg ttgtcacggg ctgcttggac
    27961 aaatttttct gctgaaacga ttgccatttt atcaggcctc ctgtatattt ttatgggtca
    28021 tcccatttac attgttcatt ttatcacttt ttgccaaaaa aatctagttt ttcccgcagt
    28081 ttcaattgat tttcttctaa ctccacctat gtaaaccctt tctctcccta gtcttggacg
    28141 acttttggaa aatctataaa gaaggttaaa cgattctcct ccatctcgaa acgataagct
    28201 aatttttcat gttctaatag actcttaacc acaaagagcc ccataccaga ccccttgacc
    28261 ttgcgactag cattgtcaga aaaagactgg gctagttttt cttgttcctc tgagctacag
    28321 ctattttcga taaaaagttc tccttctctt tctccaattc gaactaagcc acctggaaca
    28381 gagtgcttaa tggcattgct gatgagatta gaaagaatca acttcataac tgatgggttt
    28441 agataagcct gctgatgggt caaactattg tctatctgga gctctctttc cttggctagc
    28501 aaggcataat atttgaccag attttgcgtc atctggagga ggtcaattgt ttccctatca
    28561 tctcgcaatt cctgcacaga agagagggaa agtatctgca gaacatggtg attgagttca
    28621 tccacaatcc ccaaggcaac tcccagatac tggtctctat ccttataacg accgatattc
    28681 tctctcatat tttcgattag gattttcaaa ctagccagcg gtgttttcaa ttcatgagaa
    28741 gctcctcgta ggaattcgac cttcatcttc tccagctgga gaatggcttc attcttttca
    28801 tgcaagtccg caataacagt caagagatgc tggtagaggc tattgatttg ttccttgaga
    28861 ttacctatct catccttaga atccacgcgc aatcgcactt gggaatccag gtccatcatc
    28921 cgacgggtca cccgcttgat ttccaaaatc ggtgcaacaa tagtccgagc gtagatgtag
    28981 gccaccaaga gggaaatcag aaaggaggcc agcaaggtat agggaagaaa ctggagactg
    29041 atttgctccg cttccttttg taaatccatg gaagctagaa actggagaat catagtacca
    29101 ccgtcttgcg ttttcacctc gcgctcctca ataaagagag aggttgtctg gcggtctgtg
    29161 tccagaggaa gactgtcctt gacttctaac ttgtcctcgg tcatctcacc tttgacggtc
    29221 cccttgatat cactagtctg ggaatacaag tctaacactt gctcgatact ctgcctatct
    29281 ttcccttcta gggactgggc aatggctgtt gccttttgac caatagtttc ctgacgatga
    29341 ctcagataag tcgaaggaaa aagaaaataa atagctaaat gaaggcagat aaccagaaca
    29401 ctaaatatcg agaaggtata gataaatatc tttgcaaata aacctgttcg tttcattttc
    29461 gctccaattt ataaccaaca ttgcgcacag tgaggataca atccaagtct agctttttcc
    29521 gcaattcctt gatataaaca tcaataacac ggtcaaaggg aacctcatct gtcgctttcc
    29581 agacggaatc gataatctga gaccgagtca aggcccggcc ttcatttttc actagatagt
    29641 ccagaatttc caactctttg gcattgatag gcacttcttg acctgcgagg cttgcactgt
    29701 agctttcaaa gtccaccttg gtatccttgt aagaaaagat tcgtcctgta tcgtagtagc
    29761 gcttgaaaat cgcgtccacc ctcactttta agagggagag ggagaaaggt ttttccagat
    29821 agccatctgc caaagaggca aaggcactca tcttgtattc ctcatcctga aaagctgtca
    29881 acatcaagac aggaacctga ctggttttac gaatctcagc tagaacttct aagccgttaa
    29941 gcttaggcat ctggatatcc agtaaaacca gggccacctc atagctagaa aattgctcca
    30001 gagcttcctg accgtccgct gcctcaatag tttcatagcc acaatccgtc aaataatcac
    30061 tgaccccctc acggatcatc tcttcatctt ctacaattaa aattttcata ctttaactgc
    30121 tctctatttt ttatttttct tagaataaat acctactcta ttttctatta tagtctcttg
    30181 ctggcctttt gtctgtaagt aactgatcac tagataaaac gttgtgaaat tcctttctca
    30241 taaattccat agctttagta tattatattt aagcaataaa gtacaaagaa aacaactgaa
    30301 agcaatgatt ttcaccactg ctttcggatt tattttgaat tgttaaatag ccattcctat
    30361 ccactattct tgaatagaaa cacaagatgc aatctttatt ccagactcat tttttcaaat
    30421 ttattcacca tccagcaaga gctcttttgg ttgttttcta aggagattgc ttgaagcaag
    30481 cgccataacg agaaccacta gaaccaaggc aaggacaaaa atgatgataa agtctgatgt
    30541 ctgaatagaa atgtctaggc tcgacaaggt cttgctaaag ccatctactt ctgcaccacc
    30601 accaaggtta gaggcttgag ccgccttact agcctgtttg gcaacacctg aagtcacatt
    30661 ggcaaggaca gtgtttccaa ttgcacgggc agtgtaatta gctaggaagt aagcagaaac
    30721 tagagcaggg atagcaatca agatagattc ggtgatgaat tgacccaaga tacttgcctg
    30781 cttgaggccg atagagagga gaattcccac ttccttgcga cgggcgttga tccaaaggct
    30841 gagcaagagg gcaaggagga gaactgagaa gctcaagcta ccccagaaga ggaggttggc
    30901 catcttgtac ataccagaga tagattgctc aagagctggg tagttagagg agctcttgac
    30961 gagtgtgtag ctcttccagt tgataccact gatgccattc aactctttca taacatcatc
    31021 caagttcttg tctgctgtta caaagaaggt tgcgtcccca taaatggctg tgtcttctgt
    31081 gtatccataa agttttgcag cagtgtgaat gtctgtaata gctgtgtttt cgtaaagttc
    31141 ttgtgagtag gttactgctg acttattatg accatcaaag agtcccttga ttgtcacttc
    31201 aactgtttcc ttggctcctt tttcattatc tgcatcgtag atattagagt ccagtttaac
    31261 cttgtcccct actttccagc cgtgtttggc tgccaagtcc ttgtgcaaga ggattttatc
    31321 cttgtcgtcg ttggttaagt gctctccttc gactagttta taagaaccag agacaaactt
    31381 gtcttcttta gaggagtcat tgacacctgt aatcatcaag ctacttccaa aacgtttggc
    31441 acgatcagca gtgagattct tcttggtttc tggcgtttca atcaggtcat atccagtcaa
    31501 atctccgata gcgttgatac gtttgacata agactcaatg gccttgtttt cggtgatttt
    31561 tttgatgtct tcacccttga tattcccagc accgcgaggc gttccttggt tgacgcgacg
    31621 attgatttgc atggagaagc tattggtgat atttttaaag gtctcctgag aagccttggc
    31681 agtagctccc ttgattgaca agccgaccaa actcaagctc gccatgagga gaataatcag
    31741 gaagatgaca atcgatttga aaaacttcct tgtaacatag gcaaatgcgt tgtgtaacat
    31801 agattccctt tctagatttt gttttaatca ttctattaaa gtaagctcaa attatttact
    31861 agtattgcgc gtttcagtca gtttcttatc ctttaattca agtgtaatat ctgacgcttg
    31921 tgccacttct ttactgtgag ttacgacaat cacacattta cctgttttct gggcaagtga
    31981 tttgagtagt tcgacaatat ctccagcagt tttaggatcc agatttcctg ttggctcatc
    32041 agctagaata actggagctt ctgagaccaa actgcgagca atggcaacac gttgctgttg
    32101 accacctgat aactggagaa cattccgctt gatctggctt tcatccaaac caagctcaag
    32161 aagtgtattc ttgcttgcct ttttgttgac caatcggata ttttccagcg gagaaagata
    32221 atctatcaag ttataatttt gaaagaccag ggaaatatgg tgcatgcgat ggtaagaata
    32281 gcccttctta cgaatatcct ctccttgaaa aaggatagaa ccttcaacag gactatctag
    32341 accagcaagt agggacaaga gtgtggattt tcctgctcct gactccccaa taatactgta
    32401 aaattttccg ggttcaaaat tataattgat ctgatatagg actgcttcag cagtattctt
    32461 ataacggtag gtaacatctt gtaattgtaa taaagtcatg atttctcctt cttaactaat
    32521 agatgataaa atttctttcg gtgattttct aaataagaat aggaaacaaa gggctacaga
    32581 taagcaacta agcagaacta gaaaaacata ggattctgca aaagataaga tgctagttga
    32641 taaactgctt gctttggcta gtgtatcttg taagcttgcc tgatctccac ttgctagtag
    32701 agtttggagt aggtaagttg tgattccgtt tcctgcaaca aatgctggaa gcaaagctcc
    32761 aagagatacc aaaactacct ctaaacagaa ttgtaggaaa atcgagctct tgccttttcc
    32821 aagtgcaagt aaaatcccca cttcatagac ccgttctctc aaccagagag acaaaaccag
    32881 aattaaggct ccagatcctg ctatcaacat cccataaagg aagatggtca ggaaggtttg
    32941 gaaagttgca actgagtctt tgatttgttc aaaagccttg ttttcctttt cgacttggta
    33001 gccttgattt tccaaggcca agttttctac ctgcttcatg agtccgtcca tttccttagg
    33061 attttctaca tagaagcgtg ctgcactgac ttgagcttca ctattgccca aaagggtttg
    33121 gctactttca tagtctgtaa agacttgatt ttcactgaag tcagaagaca agcctgtgaa
    33181 tttctcttgt tttttaccag aaaagatgcc gataatctca aactctactg tttgtccttt
    33241 tccagattca gactgaccag catccaagcc aatcttgtca tgaagcgaaa gaccgttctt
    33301 cttagccaat tcttcgtgga taaggatttt cttggaatcc cctttttgaa ggtgtcgccc
    33361 ttcttttaga ttgaaagccg aactggtaaa ggttacatcc ttggatgaat cctcaagagc
    33421 cgttaagcta accaagttat tgtctgcagc tgataaatca tcacgctcca cgctctgctc
    33481 gccagtcact gcttccttgt cttttagttt tgcgaccgtc tcaagttcag gagagacatt
    33541 ttccagcccc ttaatcttgc ttacagatgc taggtctgac aacttgaatg tctgaccatt
    33601 ctctatcttc ttaatagaaa aagatgtatt gagtgattta taaagattgc tttctactgt
    33661 tttgttggac ttcatcagag tcaaacaggc tgaaattccg gccaataaga ccaataaaat
    33721 cagaaataaa ataaaacttc tcagtcgctt tctgctgaca taagcccaag ctctttggat
    33781 tggattcatt tgtcacctcc atatttgtaa gactattata aaacccaaat atgaaatgtt
    33841 tatgaaatac gaaaaaaaaa tatcgagtag gggataatct ctagcccctc tcacaccacc
    33901 gtacgtgccg ttcggcatac agcggttcaa ctaactttta acgcatgtcg ttcaaggtaa
    33961 taatccaaac acgaaacctg ttcacgtttt tcaaggactg gttttgatat agcacgttta
    34021 agtaccgact tctgagctac tatagtagat tgaaactaga atagtacatc tcttcttcta
    34081 aaacattgtt agaaatcgat ttggctgccc tgatcgattc gtcctactct tatttcattt
    34141 tactataatt gatagtggtc gctccagcca gataccttat ctgctatcca tttaggaacc
    34201 cctaacttaa gcaatcccca taatcgtctc gatttcttct tccattgctt ccagataatc
    34261 actcgtaggc gagtacgcaa gcgctcatct atgctagtga ctatactttt catatttata
    34321 attcattcct ttcgtttcac tcaaggcaca acacagaatg aaaaagtgtt gtgctcttta
    34381 ttttgtttta taataatagt gagaaagcct atcactacta caaatcacgg ggaggtgaat
    34441 aagtgagtgg tacagccact acctcgcata ttttgtcaca tcatttaacg gtacataata
    34501 agttgtacca tctgaataag ttgctacaat atcatttgca tgctctcctt cacctttagc
    34561 aaaggttgga gctcctgctg gataattttt atttgcctct ttcaattttt caataatggc
    34621 atttttttct gtatctttta tattatcagg atttttcact aagattttgt ctggatatgt
    34681 cggtttagca gaaacaattt ttactgttat ttctttttta ttcgaagcac ttgtccagtt
    34741 tccagcatta tctttagcat ttaattttac agtaattcct gaactaggaa cttcagtagc
    34801 aggttgatta tcaacattat tcaactttaa tttcaaaaga gctgttgcat cagacgtttt
    34861 atcaatcgtt gtatataatg atgaattgtt attataacca gtttcttcat atttagctgt
    34921 ttgtgagcta cttgaaacag aactgaaatt atgcccacta cctccctgat tatcttcaat
    34981 gcttacgtct aaatgaactt ccccactatt atttggctta gcaacaactg ttatagtaaa
    35041 ataacataaa atttgcataa atagattagg gaaatcaaag cagcttctag gaatgtttta
    35101 gcagtcacag tgtactttcc cagcatcaag ccactataac tctgcacata aaaatggaga
    35161 agatggcaat cctcttctcc aaatattaac ttctttacaa accaactata gttgacaaag
    35221 aacctaaaat caattgataa cacaaggtca ggtcggtcaa ctctttcaac tgaagccctg
    35281 tcaactcttc ccatttatca atcttgtatt ggagagaatt gcggtgcaga tagagttgct
    35341 gggctgtttt agtgagaaca gcactatttt cccaaagaga gagaatgatt tcctgaatct
    35401 gatcttgatc caaaatcatc tggtgtagac attctttaat tggcttcaag tccacgagtc
    35461 tttctcccat actccaaaga tagagctgag aaaaagtatg aacaccttgg tgaccctgac
    35521 gccaccatgt cttgaacaaa tcccgctcag ctttgattaa gtctgatagg gcttgatgtc
    35581 ctgtctgaga ccaaacctga cccaacatga tagaaagacg aagtccaaag tcatactcaa
    35641 ccgcttcaat cgtatcactt aaaatatctc ttacagaagt gtatttgtct tgttgaagca
    35701 cgaaaacata atcctgagct ccgacctgta gcactgtctg acaattcgga aaaagagtcc
    35761 gcatcatatc tagccaagaa gccagatttt cctgctgaaa ataagaaaga tggcaataaa
    35821 ccaactgaat ctttttaaaa acttgcggtg cctgtccctt gccttcaacc agataggaat
    35881 accaagggtt tagcgaacga gcctgctcct gctgggtcaa aagggcaacc aactgctttt
    35941 cacgctcgct gagcccagct tcctccagca aaatccactg ctgagaagct aaagggagcg
    36001 tgagatagcc ctctttctct actggttggt ctgaaatccg agcctcagga aaccagtctt
    36061 gtagttcttt ttccctcatg ttctagccct ccactttttg gatgcaccat gaaaccaaac
    36121 tctcaagacg ttccagattc tcagtcatat ggagatagcc cataaccgct tcaaatcccg
    36181 tggacatacg ataagtcacg acatctgcat ttttagcctt tgtgtggcta ttggtattgc
    36241 ggccacgttt gtagatttct tcttcttttt ccgttaggac ctgctcctcc aacatgagag
    36301 caatcaggcg agcctgagcc ttggctgaca catacttggt tgcttcttga tggagtttat
    36361 tgggtttggt catacctttg aggatgaggt gacggcgaat atacatagaa tacaccgcat
    36421 ccccctcaaa ggctagcgca atcccgttaa tgagattgac atcaatcacg tgtccacctc
    36481 actccatcct tggtatcaag gagcttaatt ccttgagtaa ccaattggtc acggatttgg
    36541 tctgctgtcg caaagtcacg attggcacgc gcctcttggc gtttttgaat caagtcttca
    36601 atctctgcat ccaaaacttc ctcaacaaag acaattccaa aaatttctaa catatctgca
    36661 agagcttgct tgacacttgc atcatagttc cctgagttga tccatttggc catttcaaag
    36721 acaactgtga taccgttggc agcattaaaa tcttcatcca tagctgctac aaacttatct
    36781 ttaaagtttt gtaactcttg ggcatccacg tttcctgtaa atggttgttc gtaagtattc
    36841 ttcagatact tgagattggt ctcggcatcg cgaactgcct tttccgtgaa gttgataggc
    36901 ttacggtagt gctgggtcgc aaagaagaaa cgaagtactt gcccatcaag agttttaagg
    36961 gcatcgtgta ccgtaatgaa gttacccaag gacttagaca ttttgacatt gtcgatattg
    37021 acaaagccat tgtgcatcca gtagttagca aaagccttgc ctgttttagc ttcagattgg
    37081 gcaatttcat tggtgtggtg tggaaactct aggtcagctc caccaccgtg gatatcaatg
    37141 gtatcaccta aaatctctgt cgacatgact gaacactcaa tatgccaacc cggacgtcca
    37201 ggtccccaag gactatccca agaaatctca cctggtttgg aagatttcca tagagcaaag
    37261 tctacaggat tttccttacg agccgtttct tcatcggtac gacctgaagc acctagctcc
    37321 aaatcttcca aggttttatt agccaattta gcatagttgt gggatttttc tacacggaaa
    37381 tagacatccc cttgactctc ataggcaaag cctttctcga tcaagtcttc cacaaaacgg
    37441 atgatgtctg ccataaactc cactacacgc ggatggcgag tcgcaggttt cacgcccaag
    37501 gccgtcacat cctcacgaaa ggcagcgatg tacttatccg caacctcctg aggcgtgatg
    37561 ccttcttccc tggcacggtt gataatctta tcatccacat ctgtaaaatt ggaaatatag
    37621 gcaaccttat acccacggta ctcaaaatag cgacgaatcg tatcaaaagc taccgtcgaa
    37681 cgggcgtttc ccacgtggat atagttgtac accgttggcc cacaaacata catcttgatc
    37741 ttgccgtcct caatcgggac aaattctcgc aaatcacgag acatggtgtc atagatttta
    37801 atcataaatc ataatcagga aagctaaaat ccaagaactg ttagtttcat cactaaacta
    37861 agagctcaag taaatttcag tccgaatgtc tctacacttc ggaatccctt gctcctttct
    37921 cattcagata aaccacctgt gtctgtttga caaagccaat tttttcatac aaacgtttgg
    37981 cacctacatt gctatcttcc actgcaatct gaaattcctt atcattttgc tcaattagtt
    38041 ggttgacaag ggattttgct aagtagcttc catagccttt cccacgttca ggttctgata
    38101 ttgctaaacc gtagaagtaa ttcgtatcgc tcgataaatc aaccgtgcaa gtcccaataa
    38161 cctgaccagc ttttaataaa atatatagtc ggctttctgg atctttcaga gcttcagcga
    38221 catatctatc cacaacttct ctcgattcat gttcctctga aaatgcctga aattttaatt
    38281 gactaatttg atcctgatac gaactatctg ctaacaaaat ttcaagatgg gaaacatttg
    38341 ctaacggata aggtcttcta tccttaccta accaagtttc tgtctcttca tcctcgatta
    38401 gtccccagtt actggcaaag tcaggatgat tctctaaaaa aatacgttct gtctgaaaag
    38461 tgactgaccg aatagggaaa gaagctgttt ctctctcaaa actagtaaac aatgcacgcg
    38521 caatcccctg acggcgatga cctggatgaa ccagtatcgt cacttctaca tcttggtcat
    38581 ctgcatagac agttaataaa ccaacaagtt tgcctttttc ataataaagg aaaaaggcgg
    38641 gcatgtttgg gtcaaaatta agcatgttag agagataggg atcgcgatag gtaccgtcat
    38701 agttttggca acagttaatt acttttttcg cctcagatag ctcctcttgg cttaacttgt
    38761 ttcttgcttg aatcatatag gtatcctcta caaaccagac gatctgtgac tggcatcttt
    38821 agcctgctcg agtttattga cataatactc tcgtttttct tcgacttcgt gaataacagg
    38881 ctcatctttc ttaccatgaa gacggacaat cttggccgga ataccgacaa ccgtcacatc
    38941 actaggtaca tctgctacga caactgctgc agcaccgacc ttggcatttt caccaatttc
    39001 cacaggtccg ataacttggg catgggctga tatgagggct ccctttcgta cagtcggatg
    39061 gcgtttgcca cagtctttcc ctgttccccc aagagtcact ccgtgataga gaagaacgcc
    39121 tttttcaaca atcgctgtct ctccaatcac cagaccagaa ccatggtcaa taaagacacc
    39181 tgaatcaatc tgggctcctg gatgaatctc aatctgagtc caaaagcgcc aaaactgact
    39241 gtgcatacga gctaagagtt tgaagctgtg cttccagaga aaatgcgaga gacggtgggc
    39301 cgccaaggcc ttgacacctg gataagtcag caaaacctcc aaagtggtgc gggccgctgg
    39361 atcattttct tttacgatat caatggtttc gcgccaccac cccatacatt tctccttttc
    39421 ttattctgaa tcttttggtg tttctgtaaa ttctttctta ggtttgtgat ccttgtgatg
    39481 acgtgggcgg tgagggcgct cagacttttc acctttttca tcatgctcag gttttggcgg
    39541 acgaggtaga agagccttca tagaggcatc gatacggcct ttttcatcaa tcttgataac
    39601 cttaacatca acttcatccc cgatttctac caaatcctct acacgattgg tacgagtcca
    39661 agccatctca gagatatgaa caagggcatc tgtcttatca aagaggttaa caaaggcacc
    39721 aaatttctcg atacgaacga ctttagcacg gtaaacttca tccactttgg cttcacgaac
    39781 caaaccagca ataatttctt tggcacggtt aatagcatct tggtcactag agtagataga
    39841 cacatttcct tcttcgtcta tatcaatctt aacacctgtt tcagcaataa tcttgtcgat
    39901 ggtttctcca cccttaccga tgacaatctt aatcttgtcc acatcaatct tgatcgtatc
    39961 aattttcgga gcagttggag ccaattctgg acgaacttct ggaatggttg cttcaatgac
    40021 atcaaggatt tcaaaacgcg ctttcttggc ttgagcaaga gcctccgtca agatttctgc
    40081 agtaatccct tgaatcttga tatccatttg aagggctgta atcccatcac gagtacctgc
    40141 aaccttgaag tccatatctc caaagtgatc ttccaaacct tggatatctg tcaatactgt
    40201 gtagttattt ccatctgaga taagtcccat agcaatacca gctactggcg ccttgattgg
    40261 cacaccacca gccataaggg caagagttcc cgcacagata gaagcttgag atgaagaacc
    40321 gtttgattcc aaaacttctg ctactagacg gatagcgtat gggaattctt ccaagcttgg
    40381 caagacttga gcaagagcac gctcaccaag agcaccgtga ccgatttcac gacgacctgg
    40441 cgcaccgtaa cgacctgttt cccctacaga atattgaggg aagttatagt ggtgcataaa
    40501 gcgtttcttg tactctggat ccaaaccatc aatgatttga gtttctccca tcggagccaa
    40561 ggtcaagact gaaagagctt gagtttgccc acgagtaaag agacctgaac catgtacacg
    40621 aggaaggaag tcaacaaccg catccaaagg acggatttca tcgaccttac gaccatcagg
    40681 acgcaccttg tcttctgtaa ttaaacgtcg cacttctgcg tgttccattt gttccaagat
    40741 ttcagccaca tcacgcataa tacggtcaaa ttcttcgtgg tccgcatatt tttcttcgta
    40801 aacggcagtc acttggtctt tcactgcttg agttgcagct tcacgggcca atttctcttc
    40861 tacttgaact gccttttgga ggtcactgtt gtaggctgca atgatttcag cttgcaattc
    40921 agcatccacg tgaagcaatt ccacttctgc tttttcttta ccgacagcag caacgatttc
    40981 ttcttggaag gcaatcaatt ctttgacagc ttcgtgccct ttaagaagcg cttccaacat
    41041 gatttcttct gacaattctt tggcaccaga ctctaccatg ttgatagcgt gcttggttcc
    41101 agctactgtc aattcaagaa gagattgctc tgcttgttct tgacttgggt tgatgatgat
    41161 ttggccatct acatatccca cttgtacccc agcaattggt ccgtcaaatg gaatatctga
    41221 aatagacagt gccaaagatg aaccaaacat agcagccatt ggtgcagatg cattttcatc
    41281 ataagaaagc actgtattga tgacttggac ttcattacgg aaaccttccg caaacatagg
    41341 acgaatcgga cggtcaatca aacgcgctgt caaggtcgca tctgttgaag gacgtccttc
    41401 acgtttcata aagccaccag gaaacttccc agccgcatac attttttctt cgtagttgac
    41461 ttggagtggg aagaaatccc cagttgccat tttcttagac ataacggcag cagtcaagac
    41521 agttgactca ccgtaacgta cgacaacaga tccatttgct tgcttagcaa cctgaccagt
    41581 ctctacaatt aactcacgac ccgcaaaagt cgtttgaaac acttgttttg ccattttaat
    41641 cccctttgga ttgatgaaat tatacgcctt gcctacaaag atcaagatac caaggacgtc
    41701 aaaagcaaag taaaaatagg aaactgacga agtcttcgat gaagacaaga cagtttatct
    41761 tttttacaca gcttttcggc cgtgttcaat tacacaagat attttggacg gttcggcttg
    41821 ccgaacattt ctgtagaaaa ataggaaggt gacgtcgcac tcgacgagtg ctaggaagct
    41881 tatctttttt cctaagaaat gagaccaaaa ttcaagtcat caagatacca agccgtcaag
    41941 caactcaaag gaagatagga aatcgaacga cggagcgact gctcctaggg agatttatct
    42001 ttttccacag agttgtaggc aagttcagtt ttcaagatac atcattagaa aggtttaata
    42061 ctaaagtatc taaagctttc acgctaatcg ctatcgggcg attagctaaa tgctttacta
    42121 actctctcgt caaataacat cgatttgact cactcgtgtc gttaaatctt acagtttaaa
    42181 tgcattgtat tatttaatac cttcatcttt gtatcaagta cgtacagaat ctattttatc
    42241 atatttttct taaaaagtga ggtctttacc attaaaaagg aaccattccc ctcacctgag
    42301 aagaatggtt tgcttttatt atcctagaga ctggtgatta aacaaggcat gggttgcttg
    42361 atggatgtat tttgctgtat cagcattatt catcgtatag agatgcacac cggcaacatc
    42421 ctgagttacc aagtccacga tttggtccac tgcataggca agtcctgctg ctctgagcga
    42481 ctcagggtca tgctcatact tgtctaagat ggctttaaat ttgcgtggaa gatggatatt
    42541 ctcacaagtc ttcaagagtc ggagagcctg atttcgattc agaattggca taattcctgc
    42601 atgaatggga acatcaatcc cagccaagat gcacttgtcc tgaaaatcat agaagcgctc
    42661 attgtcaaag aagagctgag ttacgaggct cgaacagcct gcatccactt tcttcttaag
    42721 attttgaata tctgaaatct gatttggcga atctggatgc ccttctggat agcaagctcc
    42781 aataatatca aagtgagggg tttgttcctt gataaactca atcaagtcgg ttgcatagcg
    42841 gaaatccttt tgtggttcca cgtctggaat aatatcccca cgaagagcca agattttctg
    42901 caccccaact ttgtccaagt cagcaatagt ttcagcaacc ttgtccttag ttagataaat
    42961 agctggcaag tgggcaatgg tcggaatcgc caaatcattt tggataaagt cagccaaacg
    43021 aaccgtcgtt tccttgatat taaatttatt attgctggca gttatactga taaaatgggg
    43081 agccaactcc tgcatatact gcaaggctga aataatgtta ccattaccca cggctgggtt
    43141 tggagggaac acttcaaatg agagtgacgg tgtttggcgt gacatatgta ataacctttt
    43201 ctagttgatt tctttttgaa caaccactgt atggagagaa atccaatctt acaatttctc
    43261 acgcgcagct ttagctgctt caacaaggcg gatcaagctt tcttttgttt ctgggatacc
    43321 acgtgttttc aaaccacagt cagggttgat ccaaactttc ttgcttggca ctttagcaag
    43381 gatggcttcg attgtgttgt cgatttcgcc ttcatttggt acacgaggtg agtggatatc
    43441 gtaaacccca ggtcccactt ctgtttggaa gtttttcgct ttgagttcgt ccaagatttc
    43501 aaggtttgaa cggctagctt caaaggaaat aacgtctgca tccatgttat cgatagctgg
    43561 gatgatatct gtaaattctg agtaacacat gtgagtgtgg atttgtgtgt ctggcgctac
    43621 tgttgagtgt accaagcgga aggcaggaat agcccagtca aggtagtctt cgtaccagtc
    43681 gctacggcgg agtggcaatt tttcacgaag agcagcctcg tcgatttgga tgattttcac
    43741 accagcagct tcaaggtcaa gtacttcatc cttgatagca agggcgattt ggagagttga
    43801 atccttgata gagatgtctt cacgtgggaa tgaccagtta aggatggtaa caggtccagt
    43861 caacatacct ttaacaggtt tgtttgtacg actttgtgca tagctagacc atttaacagt
    43921 gatagggtta agacgagtga catcacccca gatgattggt ggttttaccc cacgcatacc
    43981 gtatgattgt acccatccat ttttagagaa gaggtatcct gacaagtttt gaccgaagta
    44041 ctcaaccatg tcattacgct caaattcacc gtgaacaagg acatcaaagt caatatcttc
    44101 ttgccacttg atccattcgt caatcgtttc agcaaggaaa gcatcgtact ctttttgaga
    44161 caattcacct ttacggtaag ccaaacgttt ggcacgaact tcttttgttt gagggaatga
    44221 accaatcgtt gttgttggaa gagctggaag tttgaaagct tcttcttgga tagcttcacg
    44281 ttctgcaaag gctggcaaac gagtgtagtc tgtgtctgtc aagccagcga tacgcgcacg
    44341 aagttcagca ttttcaccaa cacgctcagt cgcaaagagt tctttgttgg ctgcaagagc
    44401 ttctgaacct tgaccattgc ggatagcatc caagtcacgg atttcatcca atttttcaac
    44461 tgcaaaggca aagtggttca agagtgctgg ttcaaattct tcattagcag ttgtaaatgg
    44521 cacatgaaga agtgagcaag agcttgtcaa aacgatgttt tcagctggga tttgctcaag
    44581 aacagccaag ctcttttcat agttgttgcg ccagatgttt ttaccattga caatacctgc
    44641 atagagagtc ttgtcagctg ggaagccacc tttaacgagt tcaagagttt tcttaccttc
    44701 aacaaagtca aaaccgatag catctactgg caagtttaca aggtcagcgt atacgtcacg
    44761 aacatcaccg aaataagttt gaagcaagac ttcaagacct tttttgtcag ccaagagttt
    44821 gttgtaaaga ttcaagaaga gagctttttc ttcagctgtc aagtctttta caagagccgc
    44881 ttcatccaat tggatgcaag tcgcaccaag ttcagccaat ttagcaaaaa cttcttggta
    44941 agcagccact aagctatcta cgaagtcgtc tgctttcacg ccttcttcaa agtctgacaa
    45001 ttgaaggaaa gtgaagggac ctacaagaac aggacgagtg ttcaatccaa gttctttggc
    45061 ttcttggaac tcatcaaaaa tcttgtgacc agccaatttt acttgagtgt ctttttcaaa
    45121 tttaggaacg atgtagtggt agttagtgtt aaaccatttc ttcattggga gggcgcgaac
    45181 gtcccctttt tctccctggt aaccacgtcc caaagcgaag tagcgctcaa ggtcagacaa
    45241 gtccaagttt tgaacggatg caggcaccac gttgaaaagg aaagccgcat ctaggaagtt
    45301 atcatagtga gaaaagtcat ttgatggaat ttcagtgatg cctttttctt tgacaatgtt
    45361 ccagtgttta gcacgcaagt cttttgctgc tgctaaaagt tcttcttctg agatttcttt
    45421 tctaaagtat ttttcagttg taaattttaa ttcacggaat tcgcccaaac gagggaaacc
    45481 gacgattgta gttgacatga tgtgtcctcc aaaatttgtt gttgaaacta tcttaacaga
    45541 aaagaaagcg tctgtataat tgtaaaaaat tagggtttga tatagtttga aactatatat
    45601 ctgtttcgga caaaagaaaa agacttgaag caaacgtctc aaatcctttg tatagcttgt
    45661 tttatagctt tatttcagtt agacggttca aacgcgttat tagtaattct tataagtgac
    45721 tatggcttgt tattagaaaa gactataact gattctagtc aactttttcc ctgttcaagt
    45781 gggacgactg ctagtgtctt tcctaaactg gctaggactt ttaagactgt atccaactga
    45841 ggactagtct ttcctgtctc catcctagct atgacaggct ggcttattcc actgacttct
    45901 tccagctttt tctgactgat tccttgttca tacctagcct caatcaactc gctcatgata
    45961 gccactcgca tatcactttc aaggatttcc tccttgctaa agagctcaga tggacatcct
    46021 tccaattact cccaatagca ctattcttca tcacttaacc ctcttttttt tacgtctatg
    46081 tatttttaaa aaaatgagcg aattatgatt cgatagattg accagtgggt ttaaagttgg
    46141 tgctagccta tttcttaagc gattttcctt ttctaggata aagcatatcc tgcttgctta
    46201 accccaattt tccacgatga atccaatagt aaatggttga aattcccacg ttaacccctt
    46261 taaccataac catcatttca ggcgaaaatt tttggttatg tatagtggag aatcttttcc
    46321 tttagtttct taagactgtt gagcgtagtc ggcagaataa atctctttga agcgcccttt
    46381 tccaagacat tgtcggactg tcccacgctt tatttcagtg tggatagttt gaggagcttt
    46441 tccaagtaga gaggcaattt ctctatttga ttttccttct tttttccatc gttcgattaa
    46501 gcgacggcta tcgattgtca aatgtttgcc ttttgtagta taattgtctt gcatttctgt
    46561 gccttttaat catttcaatc ttaaattgga ctttttttac ttgggttgta cttaatctat
    46621 aaggaagaca ataaaaagaa tatcaatcaa gtaaagtcac aaagtcacat tagctccgag
    46681 caaccattgc aaatcgaggt actcacacaa tgattaaaac atttctctct gccctttcgg
    46741 tcattctctt tgttatccct atcatagctt attctttttt tccatcttct aatcttaata
    46801 tttggctatc taccagacct atcttggcac agatttatgc cttcccctta gctactgcaa
    46861 ctatggctgc tattttaagt ttcttatttt ttttcctatc tttttacaag aaaaataaac
    46921 aaatacggtt ttactctggc attttgctct tactatcgct catattacta ttattcggaa
    46981 cagataaaac cctttcttct gcatcaaata agactaaaac cttaaaatta gtaacttgga
    47041 acgtcgctaa tcaaatagaa gcacaacata ttgagcgaat ttttagccat tttgacgccg
    47101 atatggctat attccctgaa ctagctacca atatcagagg tgagcaagaa aaccagagaa
    47161 tcaaactatt gtttcatcaa gttggacttt ctatggccaa ctatgatatt ttcacttctc
    47221 cacctaccaa tagtggaata gctcctgtga ctgtgattgt caagaaaagt tatggtttct
    47281 atacagaagc taaaactttt catacaacac ggttcgggac aattgtatta cattcgagaa
    47341 aacaaaatat accagatatc attgccttgc atactgctcc tcctctgcca ggtttaatgg
    47401 aaatctggaa gcaagactta aacatcattc ataatcaatt ggcttcaaaa tatccaaagg
    47461 ctattattgc aggtgatttt aatgcaacta tgcgtcatgg agcacttgca aaaataagct
    47521 ctcataggga cgcattaaat gtactgccac cttttgaaag aggaacttgg aatagccaaa
    47581 gtccaaaact ttttaatgca acaatagatc atattttatt gcctaaaaac cactactatg
    47641 ttaaagattt agacattgta agttttcaaa actctgatca tagatgtatt tttacagaaa
    47701 tcacatttta attattttat ataaaatcac ccctctagtg ttcataaact agagggggaa
    47761 tttgtatcat actatcgttt aacgcacttc tgcattgact ttttcttcga gcgatgcttg
    47821 gattttttcc atatagcgtg cgacttcttc gtccgttaag ctatcttctg gattttggaa
    47881 ggtcaagcta taagccattg acttcatacc aagtcccaat ttctcacctg agaagacgtc
    47941 aaagagtttg atatctgtca aacgtttcac gccggcagct tggatagcat ctacaacttc
    48001 ttgatgagtc acttctgcct tgaggagaag ggcaacgtca cggctgactg ccgggaattt
    48061 ggtgatttct acaaatggag tcgctggctg aagcgcagct tcgatagctg aaaggttaag
    48121 ctcagccaca tacgtttctg gaatatcgta agccttggca gtgactggat gcacttggcc
    48181 aaggaaacca agaacttggt caccgagtga aatcacggct gtacgacctg gatgaaggct
    48241 agcgatttca gatgttgctg tataggttac ttggagtccc aaacgagtaa atagggcttc
    48301 aaggattccc ttagcataga agaaatcaac tggaactgct gctgtttgga aatctttttc
    48361 agcaaccaag cctgtcaagg caaaggcaaa actgttgatt tcatttggaa gttcttcttt
    48421 tggattacct gtttgttcaa agacttttcc aatctcgtaa agggccaagt ttttattctt
    48481 acgagccacg ttgtaggcaa cggtatcaag gatacctgaa atcatatttt gacggaggac
    48541 tgaacgatcc acagtcattg gccacatgag ttccgtaagg ttacttggtt gagccgtaaa
    48601 ctcaactgct ttttcaggag ttgttagagt ataggtgatg atttctgtca aacctgctcc
    48661 ttcagcaata gtacgaactt gacggcggag tttttgtgtg gctgtcaatt cacctgctgt
    48721 accatcgtct tttggtagac tagttggcaa gcggtcataa ccatagatac gagcaatttc
    48781 ttcaaagagg tcagcttcga ttgtgatatc ccaacgacga cgtgggactc tgactgtaaa
    48841 gctgtctgca tttccagaaa gaccaaagcc aagacgacgg aagacgtctt ctacatcagc
    48901 ataagacagc tcagttccga ggacacggtt aacatcagca agggttgaag aaacttctac
    48961 atctgaagta tcaagctcac ccgctgaaac gatgccctta cgcaccgtcg cacctgcaag
    49021 ttccgcaatc aggctagctg ccgcatcaag ggcttcatta actgttgcca cattaattcc
    49081 tttttcaaag cgagaagatg actcagaacg aaggttcagg cgaccacttg tcttacggat
    49141 agatttgcca ttgaaaacag cagcttcaag gacaacacga ctagattttt cagagatttc
    49201 tgttgcttga ccacccatga cacctgcaag ggctactggc ttgtctgcga cagtgatgac
    49261 taggtcattc acgtccaagt cacgttcttc accgtccaag gtcaccaatt tttcaccagc
    49321 acgcgcttca cgcacacgga tgtcagtccc ttcaaagtta tccaagtcaa aggcatgcat
    49381 tggttgacca aaatagagca ggatgtagtt ggtcacgtcc actacgttat tgatgggacg
    49441 gattccttcg ttcatgagaa ggttttgcaa ccattgtgga cttggtgcga tggtcacatt
    49501 gtccaagata cgagctgcat agtaaggcgc cttgtctgtc tcaatgctga cagaaagggc
    49561 atctgccgca gcttcattag tttctgttag agtaaattct ttaaagttga ctgccttgtc
    49621 atagatggct gccacttcgt gagccactcc acacatagaa agggcatctg cacggtttgg
    49681 tgtgatggaa agttcgatga tttcatcatc caagtctagg taagaaaaga cttcctcacc
    49741 tggcacggca tcttcaggca agatttggat gccatctgcg aattccttag gcacaactga
    49801 gtcagaaatt cccaattcac caagtgaaca gatcattcca agtgactcca aaccacggat
    49861 ttttcctttt ttgattttgt agttatcagc gatacgagct cctggaagag ccaccatgac
    49921 cttgatccca gcacgcacat ttggggcacc acaaacgatc tgacgctctt cttcgccaac
    49981 gttaacctga caaacatgga ggtgagtctc tggcacatct tcgcaagaca agacctcacc
    50041 gacgacaatt tttgagagac cagcagctgg tgattcgaca ccctctacct cgattcctgt
    50101 agttgacatt ttttcagcca actcttgtga tggcacatca atgtccacca attcttttaa
    50161 ccatttataa gatataagca taatttagtt ctccagaatg accattgcca cactggttct
    50221 tttcctttcc tatcatttca atagaagaat cctcttctta ccttaatttc tttctcagta
    50281 accaatccgt atctactttt tgaccaacca taaaatgatg ttggctaaat ttttcaaaac
    50341 catatcgatt ataaaaggct tgagcttttg tattatgctc ccaaacacct agccaagccc
    50401 aagaaaaact attttttgta gcaagttcaa gtgcgaattc aaacagttgc ttacctagtc
    50461 caaatccttg gaatttttgt agcacataga ggcgttgaat ttcaaaagcg tcctctaatt
    50521 ctctctcagt ttgagcactt ccccagttga ctttgagaaa accagctatc tcctcctcat
    50581 gcataatgaa ataggtttca gagtcaggat ttcccaactc agttgacaaa gttttcagac
    50641 tataagcctc ttcaaagtat tcctgtaact gctcttccgt attatcatac gcaaaggttt
    50701 cacgaaaggt ttgtttggca attttagcca acacctcaac atctgccatt tctactttta
    50761 taatcattat ttaaactgtt ctgagaagcg gacatctcct tggtagaatc cacggatatc
    50821 gttgattcca taacggagca tagctacacg ctcttgtcca agaccaaagg caaagccaga
    50881 gtatacagtc gcatcgatac cactcatttc aaggacacgt gggtgaacca taccggcccc
    50941 cataatttcg atccaacctg ttttcttaca tatattacag ccttctccac cacacttgaa
    51001 gcaagaaaca tccacctcaa cagatggctc tgtgaatggg aagtaagatg gacgcaaacg
    51061 aatttgacgc tcttcaccaa acattttttg gacaatcaac tgaagcgttc cttgaagatc
    51121 agccatagag atatttttcc caactaccaa gccttcgatt tggtggaatt ggtgactgtg
    51181 ggtcgcatcg tccgtatcgc gacggaagac acgccctggc gagatcatct tcaaaggacc
    51241 tttagaaaaa tcatgggcat ccatagcacg cgcctgaact ggagacgtgt gggtacggag
    51301 caagatttct tcagtgatat agaaagtatc ctgcatatca cgagctgggt ggtcttttgg
    51361 aaggttcata cgttcaaagt tatagtagtc ttgctccact tcaaaaccat ccacgacttg
    51421 ataacccata ccgatgaaga tatcttcgat ttcttcactg gtttgtgtca aaacgtgacg
    51481 gtgaccagtc gcaactggac gacctggaag cgtcacatcg atactctcgc tagccagttg
    51541 agccgcgact ttcttttctt ccaagagctt agctgtttct tcaaaagcag cagtcaagac
    51601 atcacgagct tcattgacgt gtttcccgat gattggacgc atctcagcag aaacatcttt
    51661 catccctttg aggatttcag tgagcgaacc ctttttacca aggacagaga cacgcaaatc
    51721 ttgcatctct ttttcatttc cagcagtaat ctgcttcaag ctagccagcg tttcttcgcg
    51781 aagcgctttt aattgttctt caatagttga catatttcct ccatcagtct ctcgtagata
    51841 aaaagaaaac cacatgccaa aaactccact cggagcgttg acacgcggta ccatccgttt
    51901 tcatctgaca agtcagacct tcatttctaa atccatgcgc aagtgaattc acccagcttt
    51961 catatagaga gcttgcagtc acggctctcc tccctgatat acttcccttg ggctactagt
    52021 ctttcagatt cctattcaat tactacttag tttatcagat ttttaccatt cttgcaagac
    52081 ctatcttact tctgcttgtt agcttattct tatctaactt tatagcggat tgaaataaga
    52141 tga
//
LOCUS       DAVLGK010000008        48972 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLGK010000008 DAVLGK010000000
VERSION     DAVLGK010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48972
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.008"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(487..1473)
                     /locus_tag="VXE01_000535"
     CDS             complement(487..1473)
                     /locus_tag="VXE01_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0749505.1"
                     /translation="MGKSVAILMTTYNGERYLSQQIDSIRSQTFTNWTLFIRDDGSKD
                     KTIEVIQRYSKIDDRIRLVENPSKFHGAYYNFFNLIEYVKNNYQFDYYFFCDQDDIWK
                     EHKLEIQLLRFSKDDMPEMVYSDMSTIDASNNLIDISINKIMGIELPNINNLYFIQAY
                     IWGCTAGFNHALLEMVPSVDIDKDYLYIEKLAHDSYFAKFALEYGKVLFCPEQLVLYR
                     RHGHNVTTSHHFKLSPLNVFRKAILGFNELALTHARVYNQTLYMLKKASGKNPLSDRL
                     LEIQEVIKIGGLKGVRYFYQNRISRKQLVRTIGLYTIMLFGAYKKYIMKELL"
     gene            complement(1476..2195)
                     /locus_tag="VXE01_000536"
     CDS             complement(1476..2195)
                     /locus_tag="VXE01_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HEV0749506.1"
                     /translation="MSIYKLCKDIERKTMSPAKKAMAKNDYFAFYVGRPLSYLLTVPF
                     VKTNITPNQISYLSIIPLIVGFIIMIFTTDFVVLLLAWFLFFLWNLLDGVDGNLARYR
                     EQYSKDGSVVDAMAGYVAMVLTYFGAGIVAAHLTDSDIYIILGALSGISLIFPRLVMH
                     KYINTVAQDESVSSIKDKSDFNTIKILALNMTSITGIPQVLLLLTILTNQWVLFTLVY
                     FTINFLLMIFSLYSLFKKENV"
     gene            complement(2182..3306)
                     /locus_tag="VXE01_000537"
     CDS             complement(2182..3306)
                     /locus_tag="VXE01_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0749507.1"
                     /translation="MFMKLLHFSEVGGGVDRYIKLYLKYSDKEHFKNIVVGSDQLNRQ
                     TYEQEYNIKFYHIDIYRSLSPIKLLRAIKQFRKILYLERPDIVYLHSTFAGVVGRLAS
                     MGLSCKVVYNPHGWSFKMDVSKIKQFVYKNIEKFLSYLTDKYILISKSEYEAAQSLKI
                     PLKKLTLVYNGVEIDEDFNENQINVLLPINKYVIGMIGRISEQKNPFFFVEFAKKLSE
                     IYSNLYFVIVGDGELRGRTEELIEEYGLRSSFFITGWVDNPEDYLAQFNQAVLFSKWE
                     GFGLAVAEYMKHKKPILITNVDGMSELVIDGESGFKVPLYNLEVTVDRSRSIIENREL
                     ANELGSAAFQRVRSTFEIKEKVSELENIFMSLREDDNVNI"
     gene            complement(3313..4680)
                     /locus_tag="VXE01_000538"
     CDS             complement(3313..4680)
                     /locus_tag="VXE01_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0749508.1"
                     /translation="MNGKIVKSSLVIIQSSLVILLTYLLSTVREAKIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDGLIESNEVVGEL
                     VAVSVLDKPDFQHDYLKIVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIRKMAGLNVVTFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            complement(4695..5384)
                     /locus_tag="VXE01_000539"
     CDS             complement(4695..5384)
                     /locus_tag="VXE01_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV0749509.1"
                     /translation="MPTLEISQAKLDSVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     LGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSIDKYGSY
                     GNYGNYGKNKK"
     gene            complement(5394..6086)
                     /locus_tag="VXE01_000540"
     CDS             complement(5394..6086)
                     /locus_tag="VXE01_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEV0749510.1"
                     /translation="MKEQNTIEIDVFQLFKTLWQRKLMILLVALVTSAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDALEKVATNLKLD
                     MPAKTLASKVQVAVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLKIP
                     LLGLVPDFDKMK"
     gene            complement(6095..6826)
                     /gene="cps4B"
                     /locus_tag="VXE01_000541"
     CDS             complement(6095..6826)
                     /gene="cps4B"
                     /locus_tag="VXE01_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEV0749511.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLGKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            complement(6828..8273)
                     /gene="cps4A"
                     /locus_tag="VXE01_000542"
     CDS             complement(6828..8273)
                     /gene="cps4A"
                     /locus_tag="VXE01_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV0749512.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSTLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAIIKKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            8496..9017
                     /locus_tag="VXE01_000543"
                     /pseudo
     CDS             8496..9017
                     /locus_tag="VXE01_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9010..9177)
                     /locus_tag="VXE01_000544"
     CDS             complement(9010..9177)
                     /locus_tag="VXE01_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEV0749513.1"
                     /translation="MKKRILSAGLTFTSALLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(9342..10949)
                     /locus_tag="VXE01_000545"
     CDS             complement(9342..10949)
                     /locus_tag="VXE01_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV0749514.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNEDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENKKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGAKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKRVLAPWDAFCVELL"
     gene            11102..12586
                     /locus_tag="VXE01_000546"
     CDS             11102..12586
                     /locus_tag="VXE01_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV0749515.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            12681..13163
                     /locus_tag="VXE01_000547"
     CDS             12681..13163
                     /locus_tag="VXE01_000547"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV0749516.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(13230..13565)
                     /locus_tag="VXE01_000548"
                     /pseudo
     CDS             complement(13230..13565)
                     /locus_tag="VXE01_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(14017..16122)
                     /locus_tag="VXE01_000549"
     CDS             complement(14017..16122)
                     /locus_tag="VXE01_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0749517.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMSQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISDL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(16731..17711)
                     /locus_tag="VXE01_000550"
     CDS             complement(16731..17711)
                     /locus_tag="VXE01_000550"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV0749518.1"
                     /translation="MFISISAGIVTFLLTLVEIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(17713..19965)
                     /gene="pbpX"
                     /locus_tag="VXE01_000551"
     CDS             complement(17713..19965)
                     /gene="pbpX"
                     /locus_tag="VXE01_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV0749519.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(19969..20286)
                     /gene="ftsL"
                     /locus_tag="VXE01_000552"
     CDS             complement(19969..20286)
                     /gene="ftsL"
                     /locus_tag="VXE01_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV0749520.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(20298..21248)
                     /gene="rsmH"
                     /locus_tag="VXE01_000553"
     CDS             complement(20298..21248)
                     /gene="rsmH"
                     /locus_tag="VXE01_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV0749521.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFLKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            21414..21608
                     /locus_tag="VXE01_000554"
     CDS             21414..21608
                     /locus_tag="VXE01_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0749522.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            21624..22166
                     /locus_tag="VXE01_000555"
     CDS             21624..22166
                     /locus_tag="VXE01_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV0749523.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADRIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITAIDPDMLSEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            22177..22419
                     /locus_tag="VXE01_000556"
     CDS             22177..22419
                     /locus_tag="VXE01_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749524.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            22430..22765
                     /locus_tag="VXE01_000557"
     CDS             22430..22765
                     /locus_tag="VXE01_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749525.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(22875..23876)
                     /locus_tag="VXE01_000558"
     CDS             complement(22875..23876)
                     /locus_tag="VXE01_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0749526.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(23936..25837)
                     /locus_tag="VXE01_000559"
     CDS             complement(23936..25837)
                     /locus_tag="VXE01_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV0749527.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(25859..26152)
                     /locus_tag="VXE01_000560"
     CDS             complement(25859..26152)
                     /locus_tag="VXE01_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0749528.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(26152..26970)
                     /locus_tag="VXE01_000561"
     CDS             complement(26152..26970)
                     /locus_tag="VXE01_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0749529.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(26957..27736)
                     /locus_tag="VXE01_000562"
     CDS             complement(26957..27736)
                     /locus_tag="VXE01_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0749530.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(27751..28242)
                     /locus_tag="VXE01_000563"
     CDS             complement(27751..28242)
                     /locus_tag="VXE01_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0749531.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(28253..29443)
                     /locus_tag="VXE01_000564"
     CDS             complement(28253..29443)
                     /locus_tag="VXE01_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV0749532.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(29455..29889)
                     /locus_tag="VXE01_000565"
     CDS             complement(29455..29889)
                     /locus_tag="VXE01_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0749533.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            30160..30975
                     /locus_tag="VXE01_000566"
     CDS             30160..30975
                     /locus_tag="VXE01_000566"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV0749534.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            30994..31635
                     /locus_tag="VXE01_000567"
     CDS             30994..31635
                     /locus_tag="VXE01_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV0749535.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            31666..32667
                     /locus_tag="VXE01_000568"
     CDS             31666..32667
                     /locus_tag="VXE01_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV0749536.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISALEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKETYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLSGDHLSTSATSIENLLANAQDIIR"
     gene            32677..33306
                     /locus_tag="VXE01_000569"
     CDS             32677..33306
                     /locus_tag="VXE01_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV0749537.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(33685..34070)
                     /gene="tnpA"
                     /locus_tag="VXE01_000570"
                     /pseudo
     CDS             complement(33685..34070)
                     /gene="tnpA"
                     /locus_tag="VXE01_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(34450..37650)
                     /locus_tag="VXE01_000571"
     CDS             complement(34450..37650)
                     /locus_tag="VXE01_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV0749538.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPFSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            37873..38349
                     /locus_tag="VXE01_000572"
     CDS             37873..38349
                     /locus_tag="VXE01_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV0749539.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            complement(38571..40784)
                     /locus_tag="VXE01_000573"
     CDS             complement(38571..40784)
                     /locus_tag="VXE01_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HEV0749540.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFVQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDEADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETENVPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNKNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQVAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYKLEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPMYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLAFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTI
                     PVFAKSGAIIPLVGSEIDMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELTLQGDSSIVPSNRRHRIHFKGTNVSIIELPNKNDTARFECKDNKTISLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(41185..41361)
                     /locus_tag="VXE01_000574"
     CDS             complement(41185..41361)
                     /locus_tag="VXE01_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749541.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            complement(41740..43086)
                     /gene="celB"
                     /locus_tag="VXE01_000575"
     CDS             complement(41740..43086)
                     /gene="celB"
                     /locus_tag="VXE01_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEV0749542.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            complement(43166..43672)
                     /locus_tag="VXE01_000576"
     CDS             complement(43166..43672)
                     /locus_tag="VXE01_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749543.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            complement(43703..44017)
                     /locus_tag="VXE01_000577"
     CDS             complement(43703..44017)
                     /locus_tag="VXE01_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEV0749544.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            complement(44027..46006)
                     /locus_tag="VXE01_000578"
     CDS             complement(44027..46006)
                     /locus_tag="VXE01_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0749545.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDATERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVEGLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            complement(46124..46438)
                     /locus_tag="VXE01_000579"
     CDS             complement(46124..46438)
                     /locus_tag="VXE01_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEV0749546.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            complement(46568..46807)
                     /locus_tag="VXE01_000580"
     CDS             complement(46568..46807)
                     /locus_tag="VXE01_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEV0749547.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            complement(46859..48295)
                     /locus_tag="VXE01_000581"
     CDS             complement(46859..48295)
                     /locus_tag="VXE01_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0749548.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFAAQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVTADGMVHD
                     DYRIEYLDAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            complement(48485..48823)
                     /locus_tag="VXE01_000582"
     CDS             complement(48485..48823)
                     /locus_tag="VXE01_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEV0749549.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQEALDEHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
BASE COUNT        14922 a        10586 c         8103 g        15361 t
ORIGIN      
        1 ttttagatag ttgattaatc attccactta tttctacttc atttgaataa taagataggt
       61 acctatagtt acttatcaaa tctgtaatat tagaaaaact tctacctgaa aacaatacca
      121 ctttctgaat ttcacgggta taaagaaata gcataacaag atttagaatc agaagaatga
      181 catagattat ctttgaagga tttatttctt tcaattcttc atacgaaatt ccctccactt
      241 taggcctgta cgacaatttt gtcaacaagg aaactataat aaatgtagca acccctaaca
      301 atatcaaacc aaaggttttg aaatggagtt ctgttcccca aacatttcta ttaactagag
      361 cacttgcaat cgaaataaaa taagtgagtg ttaaaattac tgcaggttga aaaaaatccc
      421 cctcaaataa tataaatgta atgataatta atagaaaaat agatatgaat aagaaattta
      481 aaagcattat aagagctctt tcataatata ttttttatag gccccaaaaa gcatgatggt
      541 atataagccg attgttctta cgagttgctt tcgagaaatt cgattctgat agaaatatct
      601 cacacctttt aatcctccaa ttttgattac ttcctgaatt tcaagtagtc tatcacttaa
      661 aggatttttt ccagaagctt tttttagcat ataaagagtt tgattatata ccctagcatg
      721 tgtaagtgcc aattcattga aacccaatat agcctttctg aaaacattta gcggagataa
      781 tttaaaatga tgactagttg ttacattatg tccatgtctt cgatacaaga ccagttgttc
      841 agggcagaac aacaccttcc catactctag cgcaaacttt gcaaaataac tatcatgagc
      901 cagtttttct atatataaat aatctttatc aatatcaact gaaggaacca tctctagcaa
      961 tgcatgatta aaacctgcag tacaccccca gatataggct tgaataaaat acaaattatt
     1021 tatgttcggt aattcaatcc ccattatttt atttatacta atatctatca aattattact
     1081 ggcatcaatc gttgacatat cagagtaaac catctctggc atgtcatctt tagaaaatct
     1141 taacagctgt atttctaact tgtgctcttt ccaaatatca tcttgatcac aaaaaaagta
     1201 ataatcaaat tgataattgt ttttaacgta ttcaattaga ttaaaaaaat tgtaataagc
     1261 tccatgaaac tttgagggat tttcaactaa tctaattcta tcatctatct tagaatacct
     1321 ctgtattact tctattgttt tatcttttga tccatcatcc ctaataaaaa gtgtccaatt
     1381 agtgaatgtt tgagacctaa tactatcaat ctgttgtgac aaatatcgct caccattata
     1441 ggtggtcatt aaaattgcaa ctgactttcc catttctaaa cattctcctt tttgaataat
     1501 gaatacaaag aaaatatcat taataaaaaa ttaatcgtga aatatactaa agtaaaaagt
     1561 acccactgat ttgttaaaat agttaatagc agtaaaacct gcggaattcc tgtaattgat
     1621 gtcatgttta gagccagtat ttttatagta ttaaaatcgg atttatcttt aatgctactc
     1681 acagactcat cttgagctac tgtattgata tacttatgca tcactaacct tggaaaaatc
     1741 aatgaaatcc cagataatgc acccaggatt atatagatat ctgagtcggt taaatgagca
     1801 gctactattc ctgcaccgaa atacgtcaac accatggcta catagccagc cattgcatct
     1861 actacacttc catccttcga gtattgctcc cgatatctgg ctaagttccc atctactcca
     1921 tctagtaagt tccataaaaa aaatagaaac catgccagta ataatacaac gaaatcagtt
     1981 gtaaatatca ttattataaa tccaacaatc aaaggaatta tagataaata agatatttga
     2041 ttgggagtaa tatttgtttt cacgaaagga actgttaaaa gataggataa aggtcttcca
     2101 acataaaatg caaaatagtc gtttttagcc attgcttttt tagcaggcga catagttttt
     2161 ctttcaatat ctttacaaag tttatatatt gacattatca tcctctctta aactcatgaa
     2221 tatattctct aactctgaca ctttttcttt tatttcaaat gtagatcgaa ctctttggaa
     2281 agcagcacta cctaactcat tggctagttc tctattctca ataatacttc tacttctatc
     2341 tacagttact tctaaattat atagtgggac tttaaaacct gactcaccat caataaccaa
     2401 ttctgacatc ccatcaacat tagttataag aattggcttc ttatgtttca tatattccgc
     2461 aaccgccaat ccaaagccct cccatttcga gaaaagaact gcctgattga actgagctaa
     2521 ataatcctct ggattatcca cccaccctgt tataaaaaat gagcttcgaa gcccatactc
     2581 ttcaattagt tcttcagttc gcccacgcaa ttcgccatcg ccgacaataa caaaatataa
     2641 attgctataa atctctgata atttttttgc aaattcaaca aaaaagaaag gatttttctg
     2701 ttcactaata cgaccaatca tcccaataac atatttattt atgggtaata aaacgtttat
     2761 ttgattttcg ttaaaatctt catcaatctc tactccatta tacactaaag tcaatttctt
     2821 aaggggtatt tttaaagatt gagccgcttc atattcagat ttagagatta atatatactt
     2881 atctgtaaga taagacaaaa acttttcaat atttttataa acgaattgct taatcttaga
     2941 aacatccatc ttaaaagacc atccgtgagg attgtatact actttacacg acaaacccat
     3001 agaagctaac ctgcctacta cacctgcaaa agtactgtgc agatatacta tatcaggtct
     3061 ttctagatac aatatttttc taaattgttt aatcgcgcgt aaaagcttta ttggagacaa
     3121 gcttctatag atatcaatgt gataaaactt tatattatat tcttgttcat atgtttgtct
     3181 attaagctga tctgatccta ccacaatatt tttaaaatgt tctttatctg aatattttaa
     3241 atataactta atatacctat caactccacc gccaacttca ctaaaatgaa gcaatttcat
     3301 gaacatatcc ccctatttgg ctccatcctt catcaatact accttaactg tcttcaataa
     3361 aatttcaata tctttccaga ttgtccaatc atctatataa gccacatcta atttgacaac
     3421 ttcatcgaaa tttttgattt cacttcgtcc actgacctgc cataagcctg ttataccagg
     3481 tttaaaactt agccgacgtt tttgttctgg ggtatagtgt tcatactcat ccactgttgg
     3541 tggccgtgtg ccaaccaaac tcatatctcc ctttagaaca ttataaaact gtggtagctc
     3601 gtccaagcta gtcttccgta taaaacaacc aattttcgtg atacgaggat catcgtccac
     3661 cttaaacatt ccaccctgca tggtattttg ttccatgagt tctctttttt tcgcctcggc
     3721 atctacacac atagagcgaa acttataaaa agtgaactga cgaccatttt ttcctatacg
     3781 cgtctgagca aaaatagcag agcccccatc ctttcgaatc aaaggaacca gtacaatact
     3841 gactaaacca cataatatca acccgaccaa tgcacccacg atatcaataa tccgcttagc
     3901 aattacatga ctagtcttat aaaatgttgt agaaaaagtc acaacgttta atcctgccat
     3961 cttacgaatt tgcttgttac gtgccaaact acgatcaaaa gcatttagat tgactgttac
     4021 atcaattccc atcgtttcaa actgagagac aagctctcca atattgtatt tttcacttgg
     4081 aagattgata aagacttcat cgaccacctc atgagtcgca aagtttacta tctccccctc
     4141 tgctactatc tttaaataat catgctgaaa atctggttta tctaagacac tgacggctac
     4201 caactcccca acaacctcat ttgattctat taatccatcc agtacctttt cgacacgaga
     4261 agttgctgta agtaggagaa tcttcttact tcctttaaag ttgggataag cccgcttcca
     4321 ataccacttg ataaataggt ttagcacata gactaagaga gcatgtaatg tgaggaagta
     4381 aatcatgcct cgtctggaaa tactaaatcg atcctctaag aaaaaattag aaatactaat
     4441 cgctagtgca aagaatagga tatatttcaa tgtctggaca agttcaatca aatatcccct
     4501 tttaaagaaa tcctgtccat aatcactgat ataaaagaca aaataatgga ggatataaag
     4561 tgcaatagct gttgttgaaa caatcttcgc ttctctcaca gtactaagta gataagtcaa
     4621 taaaataaca agagaactct ggattatgac caatgaagac tttactattt ttccattcat
     4681 ctctatcccc cgacctattt tttatttttc ccgtaatttc cataatttcc ataagaaccg
     4741 tatttgtcta ttgaagtatc gaatttattc aacacaactc ccaaaaacgg cttccctgtg
     4801 tgttccaact gttcttttgc tttttgaata tcccgtcgat ttatttcacc tgcctccgtc
     4861 actaaaatag aagcatcgca ttttcgcgta ataatagccg catcaatcac gacaccgaca
     4921 ggagcagtat ctacaatgat gtagtcaaaa tatttacgca aggtttcaag cattgtactg
     4981 aaattcttac tttgaagaag agctgtcgga ttcggtgaca cagagccagc ctgaattaca
     5041 aagagatttt cgatattggt atcacaaagc ccttgtgata ggtctgtagt tcctgataaa
     5101 aattctgtca ggcctgtaat cttatccctt gctttaaaga cacctaacat aacagaattg
     5161 cgaatatctc catcaatcag cagcgttttg tatcctgcac gcgcaaaagc ccaagcgata
     5221 ttggtggaag tcgttgattt tccttctcct agtttcacag aagtgataga aaatactttc
     5281 aaaccatctc cacttaactg taggttcgtg cacaaagcgt tataatattc ctctgccttt
     5341 tttacagaat ccaattttgc ctgtgagatt tctaatgttg gcataacttc ctcctatttc
     5401 attttgtcaa aatctggaac gagccctaaa agtggaattt tcagtacatc ttcaacatct
     5461 tcaggacgtt tcacacgggt gtcgagcaac tcaatcaaaa gaacagcaat tactgttacg
     5521 actgctcctc caagaaaacc aaataaggaa ttgcgtcgaa catttggaga agagggagtc
     5581 gtagctggtc gcgcttcttc aagtgtcgtt acatcagata ctcgcgttac agcgacgatc
     5641 ttttctgcag caacttctcg tagagaatta gcgatacgac tggcttcctc tggctgttta
     5701 tccttgacag agattgagac gatacgagtg tcagctggta cagccacttg aactttgctg
     5761 gctaacgttt ttgctggcat atccaacttc aaatttgtcg ctactttttc caatgcatcc
     5821 tgcgaaagga taatctcacg gtagtctttc accagataag ttcctgcctg caaatcctga
     5881 tttgtcagcc ccggcttgtc tccttgattg cgattcacta cgtaaattcg cgtggtactc
     5941 gtatattctg gcttaacaat aaaagtgcta tatgcaaaag cccccgcact tgtcacaagt
     6001 gccactaata aaatcattag cttgcgttgc cacaaggttt taaataattg aaatacatcg
     6061 atttctatcg tgttttgttc tttcatcatt tctcctaaat tagttgatcc attacaattt
     6121 ttcgaggatt gtctataaaa agttcctgag ccttcgcttc tccgtatttt tgggtaacaa
     6181 ggtcatatgc ttctgccata tgaggaggtc taccgtctag attgtgcata tcacttgcaa
     6241 tgacatggac caaatcctgc tctaaaaaat actgagctct ttttttcatg aatttataac
     6301 gttcgccaaa aagtttgggt ttgaggacat gtgaactatt tacttgcgtg taacagccca
     6361 tatcgattag ttctcgaacg cgtttttcat tattttcaag agcatcatag cgctcaatgt
     6421 gggcaatgac tggagtaatt cccaacatca agatcttgct caaggcgcta tgaatatcgc
     6481 gataaggagt gttcatacta aactctatca aggcataacg actatcattg agggtcggaa
     6541 tccgcttttt tcccagctta tccagaacat ctggtgtgta gtaaatttca gccccgtaag
     6601 caatgactaa gtcactcgcc acttccttag ctatttcccg aacctgaaga aagttttctg
     6661 ctatcttctc ttccggagtt tcaaacatgc ccttgcgacg gtgagaggta gagacaatgg
     6721 ttcgcacccc ctgtctgtag gcttctgcca agagagcctt gctttcctct cttgacttgg
     6781 gaccgtcatc tacatcaaaa acgatatgcg aatggatgtc tatcatttca tctaccctcc
     6841 atcacatcct gtatagctgc tttaactaca gctaaactac tatcatctat ttccatcaca
     6901 tagaggttac tgtctggcat tgcataagaa ggaagatcca tccgacctgt acctttcaag
     6961 tcttgcgaat ttactttata attcccccca ctttccaact gagtattcac taaatctatc
     7021 atagtctcaa tcggcatatt tgtttgaaga gaatcctgca atccttgaag aatactacta
     7081 tagtttttca aaacctctgt agaagttaac ttcttaataa ttgctacaat gaccttttgt
     7141 tggttgcgac cacggtcacg gtctccatcg gctagtgagt agcgttcacg tacaaaacct
     7201 agagcctgct cagagtctag atggacattc cctactggga aatggaactt cccatgtaga
     7261 gttgaaaact cttgatcatt atgaacatct actcctccca ataagtcaat cattttcaag
     7321 aaagaagtga agttcaatcg cacatagtaa ttgatatcca ctccatagag attttctaag
     7381 gtgtgaatgg acgaatcaac tccataaatg cccgcatggg ttaatttatc tttttgatta
     7441 tttccaccat ctgcgattgg tacataggca tcacgtggcg ttgtggtcaa gaggattttc
     7501 ttggtatctc gattgacagt catcaggata ttgacatctg atcgcgacac cgaactaata
     7561 ggaccatagg tgtcaattcc actaacatag atattgaaag actgattctt agacgtctta
     7621 ggagcttcta cttttttagt gaatcccttg gtataaatct tttttatctt cgatgcatag
     7681 tctggatact ctgactcgat gatattttca aagacactat ttaagacaat ggccttagtc
     7741 tcccctgcaa tcaaactctt gtaagctgcc aagtaagacg aactctgatc gaccgtcaaa
     7801 tcggtattct gacttgactt gatatcagct agtagtttct gaatattttc attatcagtc
     7861 ccagtcggtg ctgtcacact cgtcagttgc gtaacatttt cgatctcact atctgctaaa
     7921 acagcgacac tgattgaata ttctgagtaa ttagaagtcg catttaaacg attggtcagt
     7981 ccaacaaact gctgtactgc aaagagcgac acagagctga caaggataga gaacaccaac
     8041 agaaaaatag taaatttttc agctttttta tagataatca ggagtagccc taccaaggca
     8101 actagtagga ctaacgcagt taccactaga ttaagatatc taaaagcaag gatattgtac
     8161 ttaaagatta agaacaataa aaaacaaact aacaataaat aaatagtcaa caaaactata
     8221 ttaacacttc gcttcacttt ctgtgaacct gattttttaa aacgtctact catgattaac
     8281 acctatacat tgaacatcat acgattatat cactttttta cggtaatgtc tacacctttt
     8341 ttcactatct gcatctttaa gtatcttagt agacttcccg cgaaacaaaa atatagtaaa
     8401 atgaaataag aacatgacaa atcaatcagg acagtcaaat cgatttctaa caatgtttta
     8461 gaagcagagg tgtactattc tagtttcaat ctaattatga acaagaccca gaaaaagtag
     8521 ccttatttct taagaatttt aatagtttaa agcacctagc acctgtttag attgacgaaa
     8581 caggattcga tacttatttt tatcgagaat atggtcgctc attaaaaggt cagttaagaa
     8641 gaggcaaagt atctggaaga agatatcaga ggatttcttt ggttgcaggt ctaacaaatg
     8701 gtgagttaat cgctccaatg acttacgaag agacgatgac gagcgacttt tttgaagctt
     8761 ggtttcaaaa atttctctta ccaacattaa acacatcatc ggttattatt atggataatg
     8821 taagattcca tagactgggg aagctagaac ttttatgcga agagtttggg cataaacttt
     8881 taccttcttc ctccctactc acctgagtac aatcctattg agaaaacatg ggctcacatc
     8941 aaaaagcctc gtaaaaggta ttaccaagtt gcaatacctt ttatgaggct cttttgtctt
     9001 gttcttgttt caattgacta tattatcagc gtaatagtct aatagatagt taaatgtagt
     9061 tggatttcca ctaaaggttg atgagtaagt ttttgtatct gaacctgatt ggccgcaagc
     9121 agctaaaagc aaagcagatg taaaagtcag gcctgcacta aggatacgct tctttatgtt
     9181 cgtcttcttt ctccttaata gtgggaattt gtaaagttaa ttgaatttcg agaatgaagg
     9241 tttataaacc ttggttataa aaaacaaagg atttctgcct tttatacagt cctcccttgt
     9301 ttttatacga tttcaatttt aaatttttct gcaaaaaata tttatagtaa ttccacacag
     9361 aaagcatccc atggagccaa gacccgtttt tcaagtactt ctttagccgc agtgttttca
     9421 atcaagacag atttgacttt tccttctact gtcaagtctt gctcttcatt ggacaagtta
     9481 gccacaacta ggaagcgacg gtcgccatcc ttacgtatat aagcaaagac cttatcagcc
     9541 gtatcaagca attcaaagtc agctcgaatt agccagctat tctccttgcg aatttggacc
     9601 agtttctgat aggtatagaa aatagaatct ggatttgcca gcgcttcttg gacattgatc
     9661 atctcgtaat ttggattaac cgccaaccaa ggttgacctg ttgagaaacc agcgtttttg
     9721 ctctcgtccc attgcatagg ggtacgggca ttgtcacgtc caataacacg gatactgtcc
     9781 atgatttctt caatcggaac acctttttca agagcctcac gcgcatagtt gagagattca
     9841 atatcttcta cttgatccag tgtttcaaac ggatagttgg tcatcccaat ctcctcacct
     9901 tggtagatat aaggagttcc tctcataaga tgaagcaaga ttgcaaaggc tttggcagat
     9961 ttttcgcggt attcttggtc atttccccag attgagacga tacgagggag gtcatgattg
    10021 ttccagaaga gggaattcca accgtcctca actcctaact ctgtctgcca tttgttgaag
    10081 atttctttta acttagcgat attcagctct ttttgatagt gccatttagg ctgaccttcc
    10141 tgatactgaa gaccgatatg ttcaaactgg aagaccatag acaattcttg cccctttgga
    10201 tcagagtaga gcttggcaat ctctggcgtt gctccccaag tctcccctac tgtcaagaga
    10261 tccttagctc caaaggtcgc ctgattcatt tccttgagat agggatggag cataggacca
    10321 ttattgacta ccttctcatc aggaattttg ccaatcatgt caataacatc catacggaaa
    10381 ccaccaatac ctttatcaat ccagaagttc atcatctcat aaattttctg gcgaagtttt
    10441 ttattttccc agttgagatc cggctgtttc ttgctgaaaa agtggagata gtattgacca
    10501 gatttttcat cgtattccca agcagatcca ctaaaaatag aatctaaatc gttaggctca
    10561 tcccgccaga tatagtaatc tcgctcaggg ctattaggat tttcacaggc ctctacaaac
    10621 caggcatgct catccgaggt atgattgacc accaagtcca tgatgatacg gatatcacgc
    10681 ttcttagctt ctgcaatcag ttgatccatg tcctccatgg ttccaaaaat agccgcaatc
    10741 gcttgataat cagcaatatc atagccatta tcatccatag ggctgtcata aacgggagaa
    10801 agccaaattg ctgtgattcc tagcttggct agatagtcca acttactggt aattcctggc
    10861 aaatcgccaa ttccatcttc attactatcc ataaaactct ttggatagac ttgatagact
    10921 acggcattgt gccaccattt ttcttgcatc ttcttacctc attattttca taatctatag
    10981 tctatgatag cactttttaa aattttgtgc aagcgtttgc ttaatctttt taatttcttt
    11041 tttagctccg tagtttccta acttccaatt ttttattata atagagtcca gaggtaaaaa
    11101 aatgaaaaaa caagctttta gttctgaaca atatttaaat ctacaacgcg accacatctt
    11161 agagcgcatt aaccaatttg acggcaagct ttacctagag tttggtggca aaatgttaga
    11221 agatttccac gctgctcgtg tccttcctgg ttatgaacct gacaacaaaa tcaagctctt
    11281 gcaagaattg aaagagcaag ttgaggttgt gattgccatt aatgctagca acattgaaca
    11341 ttccaaagca cgtggcgact tgggcatttc ttatgaccaa gaagttcttc gtttgattga
    11401 caaattcaat gaattaggga tttttgttgg ttccgttgtc attacacaat acgctggcca
    11461 acccgctgca gatgccttcc gcaaccaact tgagaaaaac ggaattgatt cttatcttca
    11521 ttatccaatc aaaggatatc cgacggatat ggatcacatc atttccccag aaggcatggg
    11581 caaaaacgac tacatcaaaa ccagtcgcaa cttgattgtc gtaaccgctc ctggacccgg
    11641 ttctggaaaa ttggcaacgt gtatgtccaa tatgtaccac gaccaaatca atggcatcaa
    11701 gtctggctac gctaaatttg aaaccttccc tgtttggaat cttccccttc atcacccagt
    11761 taacttggct tatgaagctg ccacagctga ccttgatgat gtcaacatga ttgacccctt
    11821 ccatcttcaa acctatggag aaaccactgt caactacaac cgtgatatcg aaatcttccc
    11881 agtgctcaag cgcatgttgg aacgtattct cggaaaatca ccatacgctt caccgacaga
    11941 tatgggtgtc aacatggttg gtttcgctat tacagatgac gaggctgctg tcgaagcttc
    12001 taaacaagaa atcatccgcc gttactatca aacagttctt gacttcaaag ctgaaaaagt
    12061 tggcgaagct gccgtcaaga aaattgagtt gctcatgaac gacctcggta tcacacctgc
    12121 agaccgtaag gttgctgtcg ttgcgcgcca aaaagcagaa gaaactggtg gaccagccct
    12181 agcctttgaa ttgccaaatg gggaaatcat cactggtaag aactcagaac tctttggccc
    12241 tacagccgct gccttgatca atgccatcaa aaaatcagct gacatcgcta aagaagtaaa
    12301 actaatcgag cctgaagttg ttaagccaat ccaaggtctt aaaatcgatc atctcggtag
    12361 ccgcaatcca cgccttcatt caaatgaaat cctgattgca cttgctatca cagctacaga
    12421 aaatcctgat gctgcccgcg ctatggaaga actcggcaac ctcaaaggaa gcgaagccca
    12481 ctcaaccatc atcttgactg atgaagacaa gaatgtcctt cgtaaactgg gtatcaacgt
    12541 aacctttgac ccatactacc aatacgaccg cttatatcgt aagtaaaaat ttcaacctct
    12601 ctagcctcgg agaggttttc tctctgtctc aggaacaacc tttatgatat aatgagagaa
    12661 gaaaactgaa aggatttacc atgtcaaaag aagttattgt cgaaagtttt gaacttgacc
    12721 acaccattgt caaagcaccc tatgttcgct tgattgggga agaaacagga ccaaaaggag
    12781 acattatctc caattatgat attcgcttgg tgcaaccaaa cgaagactct atccctactg
    12841 ccggccttca cactatcgag cacctcttag ccaaactcat ccgtacccgc attgacggca
    12901 tgattgactg ttcaccattt ggttgccgca caggcttcca catgattatg tggggacgtc
    12961 acaccagtgc taaaatcgca gctgttatca aggattcgct caaggaaatc gctgaaacta
    13021 ctacttggga agatgtccca gggacaacca tcgaatcttg cggaaactac aaggaccaca
    13081 gcctcttctc tgctaaagaa tgggcaaaac tcatcttgga acaagggatt tcagatgatg
    13141 cctttgaacg tcatgtgatt taaaatcgag taggggataa tctctagccc ctctcacacc
    13201 accgtacgtg ccgttcggca tacggcggtt caactaactt ttaacgcatg tcgttcaagg
    13261 taataatcca aacacgaaac cagtccacgt ttttcaagga ctggttttga tatagcacgt
    13321 ttaagtaccg acttctgagc tactaattga tagtggtcgc cccagccaga taccttatct
    13381 gctatccatt taggaacccc taacttaagc aatccccata atcgtctcga ttttttcttc
    13441 cattgcttcc agataatcac tcgtaggcga gtatgcaagc gctcatctat gctagtgact
    13501 atacttttca tatttcccaa tgagaaatag tttatccatc ctcgaacaga caaattcagt
    13561 tgctctcgtg atttacgcat ataggctacg actacctttt tgaactttag agtttgaggc
    13621 cccttatccg ctatatacgc cttattatca cgttcctatt cgtagagcca cgatttcgct
    13681 atcccttcct ctgacgattc ttatttccag cgtcagactt aaaacggtct atccccagac
    13741 cgttttaatc cgctacctca cgatagtcag gcttgggaat cactattggg agcaccggta
    13801 gcaggtaccc accgaggact tacacctcag atatatagta aaatgaaata agaacaggac
    13861 aaatcaatca ggacagtcaa atcgatttct aacaatattt tagaagtaga tgtgtactat
    13921 tctagtttca acctactgta cgacatgccc gtcgtaccta aaaaggaacc agtttttttc
    13981 agctggctcc ttctttttta tcctcaaaat tctgtcttag gctttctcac gaataaccaa
    14041 aacgccatct tccatatctg cttccagatg tttagcatct aaatgatcca agtggaagtc
    14101 tgtcacctta tcacgaattt cttgttcaac cactcgacgg agaggacgaa cccccatgac
    14161 ttcgtcgtaa ccttcttctg tgatataatc tttagccgct tgactaacta ccaagtcaat
    14221 gtctttctta gccaaggttt ggttaacttc agccaacatc aaatctacaa tcttagaaag
    14281 gtcttcctta gtcaagtgtg agaactcgat gactgcatta aagcggttga ggaattctgg
    14341 acggaagaag ggtttcaaac ggtccatcaa ttctggttta tccgcatctt ctgtcaagtt
    14401 ggcttcatag ccaaatccag catttgaggt cgcaataatg acagtgttct tgaagtttac
    14461 tgtatttcct tgaccatctg tcaaacgacc atcatctaga acttggagga gaagggtaat
    14521 aacttgaggg tcagcctttt caatttcatc caagagaatg atagagtatg gattgcgacg
    14581 aacacgttct gttaaggtat tgctattgtc atcataaccc acatagcctg ctgttgtacc
    14641 aattagctta gaaacagctg tacggtcact gtattcagac atatccaaac ggataatcgc
    14701 atcctgggtt ccaaacatat cgagtgccaa ttgcttagca agctccgtct taccaacccc
    14761 agtagaccct acaaagagga agctgccgat tgggcgattt ccttcatcaa aaccagcacg
    14821 gttacgacgg atagcacgag ctacagcttc tacggcctta tcttgaccaa tcaccttgtc
    14881 ttgcaagcga tgagccatat ctttcaaacg ttcgatatct gaagctccca tttgcgatac
    14941 tgggatacct gtcattcgtt ccacagattc agccacatcg ttgacacttg cagtcacttt
    15001 catatcttct gtgtggtttt cgattttcct ttccaattct gcaatgcgtg ttttatagtt
    15061 tagagctgct tcaaaatctt ctgcttcaac tgctttttct tgcttgtctt tttccgtttc
    15121 gatttctcgt tcaacagcat gcacatctgt tactggatgt tgagccgcca agtgagcagc
    15181 cgttacatcg acaaggtcaa tagccttatc tggcaagcta cgttgaggaa tgtattgaac
    15241 agaataatcc accgctgctt tcaagacttc gtctggcaag atgacattgt ggtgttgttg
    15301 atagagatca cgaatgcctt gaagaatttt aaaagtattc tctgctgaag gagcattgac
    15361 cttcacttcg ttgaaacgac gagcaagagc agcattcttc aagatggtgt tacggtattc
    15421 gtcttgagtt gttgccccaa tcactgtcaa ttctccacga gagagagctg gcttgagaat
    15481 atccgcaagt cctttagaac cactgtctcc accagtgcta ccagcaccaa gaatttggtg
    15541 aatttcatca aagaagagga taatattccc tgcttctttc acttcattga ctaagttttg
    15601 gacattttct tcaaagctac cacggtattg agtaccagcc tcaagatctg agatatcaat
    15661 agaaataatt tccttgttct tgatagcagc aggaacatct ccgttcacaa tggcttgcgc
    15721 tagaccttcg acaactgctg tcttaccaac acctgcatct ccgaccaaaa caggattgtt
    15781 cttggtgcgg cgtgagagga tttcagatgt ttcttgaatt tccttgtttc gtccgataac
    15841 aggatccaac ttgccctcac gcgcttctgc tgtcaagttt cgacctagtt ttgcaaggac
    15901 accgtcttgt ttcatacctg atgcctgttg tgacatttgc acatcagttt ctgcatttcc
    15961 tggtaattga ccagtcgtac gatagtgagc aaattcctca ggtgtgactt cgcgcccatt
    16021 aattaagtaa cggcgatttt cagaactgta tcctcgcata ccacccatca attggttaaa
    16081 taaatcatcc atgttattaa aattattaaa gttgttattc atattcttta cctctttttg
    16141 tttacttagt tatgattact gatattgact atctttgacc tttgttttaa aaaatttaga
    16201 ctagctaaac cgctacccta cgtactattt ctggtttttc tttttcaagc aggagtagac
    16261 tatctttact tctgaaaatt tctagatgaa acatagaccc acctctttct attttacttt
    16321 aaataagtgt tctagtaagg ctttcattta ccttacgttc ataatatact acattggtca
    16381 gaaaaggtca agggttttga ctttaactga ccaatatttt tttacactct tcgaaaacct
    16441 cttcaaacca catcagcttc tccttatcta caacctcaaa accgtgtttt gagctgactt
    16501 cgtcagttct atcaaccatc tcaaaactgt atattaaaac gaaataagaa caggacaaat
    16561 caatcaggac agtcaaatcg atttctaaca atattttaga agtagaggtg tactattcta
    16621 gtttcaaact actatgtttt gagcagccta aagttagctt tctagattgt tctttgattt
    16681 tcattgtgta tttaaacaca aaaacaccct gaaacatcag ggtgccattc ttacatcaaa
    16741 tataaaattg cgagggtcag gagacttgct agaagtccca ctccccaaaa gaagaagtca
    16801 accttccact cgctccaagg atttccttta ccagacaatc ccccaagctc aaaatggtga
    16861 tgtacaggcg tcatacggaa aatacgttta ccacctgtca gtttgaaata actgacttgc
    16921 atcataacag aagttgtttc aaaaacatac acaattccga taatcaagag agtccattct
    16981 tggtggagag ccatagagat agctgccagc atcccaccta gggccaaact tcccacatca
    17041 cccataaaga ccttggcagg cttatggtta aagataaaga aaccgagcaa accaccaatc
    17101 atggcaagaa tcactagaag aatatccatc tgaccttgca cataggcaat aactccatag
    17161 gcagacaaac taatcacaac ggaaatacta gctaaaccgt caacaccgtc tgtcaagttt
    17221 actgcgtttg aaaaaccgac tagccagaaa agagcgaaga aaatatagaa aaatcccaaa
    17281 tgaactggat aaccaaagac agacaggata tcgccaccgc gctcatagaa aagatagaag
    17341 ataactccac ctagaagctg aagagctaat ttttgcttag gattaagccc ctcattgatt
    17401 ttacgaaaga ccttgagaaa gtcatctaaa aatccgacca agccatacaa gaccaagatg
    17461 aacaaaatca ttcccacatt attgctgaat tggctactaa atagggcgaa aaagaaagca
    17521 accaaaacag aagtaatcaa gaaaaccaaa cctcccattg taggagtccc agcttttgcc
    17581 tgatgctgtt tgacatcctc atgcatctgc tggcctgtaa tttgcgcctt tctataaaat
    17641 tggataaagg ccggaatttc tactaaagtt agtaaaaatg tcacaattcc agcactgatg
    17701 gaaataaaca tattagtctc ctaaagttaa tgtaattttt ttaatgtcct tgatagctgt
    17761 gttagcacga acatcttgct tctgcacagt agagcccgaa ccttgaaatt caagttctat
    17821 attgagccac ttagcaaggg tctcagcagt ctcctttgtc caaccataca tatctggaac
    17881 ttcctctgct ttatcagata agataaggac ctgctgattc ggggcaagat tcttcccttc
    17941 ttcagcagaa ctgtttttaa tcttcgttcc tgttcccaca acgatgggtt gtacaagatt
    18001 gcgacgcaat tcttctgcta aatcaccagg tgaaatatcc ttgacactag gcataggata
    18061 aggactttgt tgacttactt gctccaaagc cttagctgtt gtttgaagat tgagagagtc
    18121 tttcatagct gaagcccgct ccaagatagg attggcaaat tctcccaact gaatacctga
    18181 ataatgttca ggttgttgga ccgtcacata caagataaaa tcaggatttt cagccggact
    18241 catcgataca gccgagaaaa tatagtcggt taacccgact agataaccac catttttctc
    18301 gtcagcaatc tgagccgtac cagacttgag ggctacattt tgcccaggaa cagttacagt
    18361 tggcttgcct gtgctgtggt tatacatggt tccataaacc ggatccgtcc ctaccaaaac
    18421 catgttagtc cgagttagac tagctgcatc tttagaaaca ggatttccca caatttcttt
    18481 ttgagatttc cgagcagttt gatcatttgg atcataaatg gcactaataa atttaggctc
    18541 cagcatgaca ccgtcattag caatagctgt aaaggcacga atcatttgcg tctgggtcac
    18601 tgaaatccct tgtccaaatg agctttgcgc aatgttgaca atattatccg caggaagctg
    18661 accagcatac tcatccgtca aaccgaaacg ggtcggaaca ccaaatttaa aacgattaag
    18721 ataatcaagc caggtagcat ctcccatctt ttgctcaagg agagtcatcc caacgttact
    18781 tgagtgtgca aaaccttgag aaaaagtcat cattctgcca ccagtcaatc cttcattaac
    18841 gtcccaatct cgaatcgtgg catctgcaat ttttaactca ctactattaa agacttctcc
    18901 tcctggaaag gtattattat caatagcagc agccaacatc atcactttca tagtggaacc
    18961 tggctcatag ttactttggt aaaggatatc acgccaaaca aagtcctctg taatgccttc
    19021 ttttgtatct gcatcaaagg tcggtcgttg cgttgttgcc agaatttccc ctgttttagc
    19081 actgaccaaa gtcgctgtca tgtactttcc ttttaccttc tcttgaaaag catccatctg
    19141 ggtttccata aaggactgga gggggctgga aatggttgta taaacatcct taccgtccat
    19201 cgttcgttgg gaaacttgtt ctgttccagg tacaatatta cccagacgat ccttttcata
    19261 ggtaataatg ccgtctgtcc ctgcaagaat actgttcaag gaactctcca ttccagaggt
    19321 tcccagcaag ctcttgcttc catcttcatt ttcatggagc tgagctaggc cgataaaact
    19381 agaagcaaat tgtccgtttg ggtaactacg attgggactg gttgtaaaat caatcccctt
    19441 gacctctgca gcttccaatt cttttttgat agacatcata ttggcatagg taatcccatt
    19501 tccctttgct ccaaaggaaa cttgcttgag attaggttgc gagagttgct ctcttacata
    19561 ggattcttcc atgtccagat acttatgaaa gacctctgca accttgttaa attgtgtttt
    19621 ttctacgtaa agaatcttac ccgttgctga cttatagttc tcatcaatga ccgcatagac
    19681 attataggag gttgcatcct cagcaatcgg gactccattt cggtcataaa tagtcccacg
    19741 tttggcagga actgtacggg tggtttgatg aaccttctta gcttccttcg ctaaatctgt
    19801 tccaaagcga gtgcctgtcc caataatgac cgcaaaattg actaaaaaaa tggcaaaaac
    19861 aaagacagat aataaactca gactttttcc aactctgcgt ctgttttcag ccggcgattt
    19921 ccgatttttg gtcgcataac ggattactct ttttgtccac ttcatatctt actccgctat
    19981 tctaatattt tcattgttta attgcaaatc gtgtgaattg gcaatttctt tcaaacgttc
    20041 tgcacgtaat agttcattga cctcttgctt ggcatcgtcc aattcggttt tcttttcctc
    20101 tatctgcgca ttgatttttg tcaaatcatt ctgcacttgc aagagcttgg tctgcataaa
    20161 aataatacta atggctacaa taagagtggt tacagcaatg gaaaagtaaa aagctttttc
    20221 cacacgcgaa aaccgtttaa gttgcatctg tagtatttga cctgtttttt ccattttttc
    20281 tgccatcttt ttccctctta cttgtgaatt tttctggcca cgcgcaactt ggctgagtgc
    20341 gagcggttat tggcttctaa ctcttccgca cttggcaaga ttggcttacg ggacaccaat
    20401 tccatcttgg gcttgagatc atctgggatg aaaggcaagc cttttggaac ttcaactgtt
    20461 gaagcttcct tgaacaattg cttggtcaag cggtcttcta aggaatgaaa ggtaatcact
    20521 gaaattctac catccagagc caacatatcc atagcctgct ggatggactc atctgccgct
    20581 cccagttcat cattgacttc aattcgaata gcctggaaaa tctgcttagc aggatgaccc
    20641 ttcttcttga gttccttggc aggtttgacc aacttgataa tctctgctaa ctcagtcgtt
    20701 gtctcaatcg gcttcacttc acgcgcttgc tcaatcttac gcgcaatctg tttagagaat
    20761 ttatcctcac cgtattttaa gaaaatacga accaaatcat gatagtcata gtgattaacc
    20821 acttcatagg ctgtcagact agcatcctga ttcatccgca tgtccagtgg cgcatccttt
    20881 ttataagaaa aaccacgctc acgctggtcc aattgaggac tagacactcc caagtcataa
    20941 caaattccat caatttcctg aacaccagct tcgcgcaaac gtgcctgtaa atgacggaag
    21001 ttatccttga taaaggtcac cattcccttc tcaatgtaag gtgccaagcg tttttgcgca
    21061 ttgtcaatgg cattctgatc ctggtcaaag gcatagagat ggcctttttc acttaattta
    21121 cttaataaat actcgctatg gcctgctcca cccaaagtcg catcaacgta gataccgtca
    21181 ggttttacgt caagcatatc aatcgtttcg tggagtaaga ccgttacatg atgaaattct
    21241 tttgtcatat cttatctatt ttaccacaaa tccgaccagc ttgcacttgt cagacaaata
    21301 ggacaaggag actactattt cttcaaaaaa tatgtcaaaa atacttgaca ctttatgttt
    21361 aaaagactat aatatagtca aatatatacg acataaatca gaaaggagac cagatgaatc
    21421 gtgtgaaaga atttcgcaag gaattgggta tttcccagct cgaactcgcc aaggatatcg
    21481 gtgtctcgag acagactatc aatatgattg aaaacgacaa gtacaatcca accttggaac
    21541 tctgtctcaa tctcgcccgc agcctccaaa ctgacctcaa cagtctcttt tgggaggaag
    21601 atttttaaaa aaggagcaaa ctcatgaaaa aagaaacctt cactgaaaaa ctgatcaaac
    21661 gcacatacgg tatttctggt ccccttgacg aatacaaacg gcgtgaggcc gatcgtattg
    21721 ggaaccaagt ctttatcatc ctcttttatc tgatgatttt cggaaatctt attccactcc
    21781 ttctggccta taaataccct caagaagtgg ctctaatcta tcctcctctg attttagtga
    21841 ttgccctcat cgctgctggc tatgtcacct accaaatgaa aaaaacaggg attacagcta
    21901 ttgatccaga catgctgagc gagaaagaaa gtaagcaact acattaccca ggtctgaaag
    21961 caggtttgtt ctttggtcta tggatgtttt ttataactcc tcttctcagt atactcatag
    22021 atgaaggtca ggactatttt cattctcttc tcactataag aaatggtgta tcaagtattc
    22081 tcggttctat tttcttcgga gcgagcatac agttcctcat ctcccgtcgc attgcaaaaa
    22141 ctaagaaaaa tcaagatgag gattaggagg aaactcatga aaaaagaaaa gaaacagtta
    22201 cgttatcctg gtctgaaagc aggttcgatt tatggaacag tgatattttt tataattcca
    22261 ctcattgata ccctaacaag tgaaaatcca aattttatca gttctcttct aaatacaaaa
    22321 catattttta aaactatact gggagctttc tttttcggag tgatgataca tattgtcgac
    22381 tcacttcgta ttgcaagagc taaaaaagac caggattagg aggtgcctta tgaaatcact
    22441 agctagacta ctgatcattc atgtttttat cagtattttc cttttcttcg cccttacttc
    22501 aggagctatt tctcatacag ttttactact cctactcctc tttcttcctg cgctcaataa
    22561 aggacttgag aaaatacaat caaaacggat acctgtcctc aacgcagccc tcttctttct
    22621 cctcatatcc tttccacaac ttttaactaa ccctgtccaa tggaaatttt caatattcct
    22681 agtcgtaacc atcatttcaa gtttggccta cttctataac ttttatcaag tagttaaaga
    22741 agtagatcaa aaacagttga tttaggagct tgctcccata atttctcatt tcataggcaa
    22801 ataatcccac ctagcttgtt ctaggtggga ttattttatt tcttaacaga aattgcaagt
    22861 cattttcctt cattttagaa agtcgactct ttccaattca cactacaatc caagacttgt
    22921 tgcctttctt cttgattgcg gccttcaatc tgatcaatca aaatctttgt agcctgttgt
    22981 ccttcctcaa aggagggctg aaccagcgtc gaaacacttg gagaagaaaa gcaagtccac
    23041 tccgtattgt caaaaccaat caacccaact tgcggcaagt tataattcaa ctctttgata
    23101 acggtaaaga ctagaggtag ggcccaacag ttagggataa ataccagagt tttttcatcg
    23161 ggatcgattt ctttttgtaa aaattcttta atttgttcca aattcgtatg cttatcttca
    23221 atggttagac tggcgtgacg catattagca tctgttaaag catccacaaa accacttgcc
    23281 cgctcaatcc gagtactcaa acgactcgta tccgctgtaa tcaagagaaa atgctcataa
    23341 cctttttcga tacaggactg ggtcatgtca taaacggcat catagttatt ggttttaacc
    23401 cagctagtcc ggtgttcata gagctgacta tcaaaaaaga ccattttctt ctttttctca
    23461 tcgatgatac gagaatattt tcggaaatta gaggtcggct gaataataaa gccgtctact
    23521 cccaagagaa gcatgctttc aatataccgg tcctcactct cttggctgta attgctattt
    23581 cctatcatta cctggtagcc attctggctg gcgatatcct caattccctt aacaatttgg
    23641 tttgagaaac tgttggtaat atcaccgatc aaaacaccga ttaattttgt tcgtttggag
    23701 tttaagctac gcgcaacaat gctcggtttg taatttgttt catgaataac tttttcaatc
    23761 ttttcacgtg tctcttggga cattttttca tatttcccgt ttaggtaaaa tgacacggtt
    23821 gttttcgagg tctgagccat ttccgcaatg tcttttatgg tcagtttctt ctccaatcta
    23881 aaacacctcc tactaatact tattataaca tattcactat tcaaaatgcc tatttctagc
    23941 actgcaagcg aatcattctc tcatttattt tatcatatac tagacatttt ccacgcattt
    24001 ttgttccgtc aacgaggcac aatttttcac ctacacaaat atcctcgctt aataacagaa
    24061 tcagcttgtc tgtttcgtca tttttcactt caaaagccag agcattttcc acttcacgat
    24121 catctgtctg gtagacagaa tgacggatga tttcaaaact ctcatgcgca atgatggtat
    24181 aatccagcat ctgattctca aagaattggc gcttggtgag tttgttactt ctttcaagct
    24241 cattgtattt aggagaaatg atggtatctt ccaaatcaaa atcaacttca ctccatagtc
    24301 tcaactgatt gattttccca tcttgatagg tcacatcctt gtcaaggata aactgagtca
    24361 acgcctcatg ctgaccttga cacctgatgt catctaccaa gagccagaca tcctctacca
    24421 acatgaggat ttttctcttg tgaagataag gcaaatcagg ttctgctgac caataagccc
    24481 cctcaatata atgcactccc tccctttctt tatggtgaca aaacagggag tgaggatagt
    24541 attcatattc ccaggatccc gtgattcttt ccggagcttt cccatctaca atgcaggtcg
    24601 aatgactcca agcactcttt aagagataac gttcatatat ctcccgataa gaataacgcc
    24661 cagcatctat gaaaataggt tggccttgat actgtaaaca aaaactattc tcgtcactat
    24721 ggctatgggc acttcctagc ggaccatttt tgaaaaatag ataacgatgt tcatccttaa
    24781 tgcagacatg tccagagtct tcaaagatca tggacttagg ctgccaagct ctcctttcaa
    24841 attcctgcag tcgcttgacc ttttctcgcc ccaggaacaa gaggctaagc aaatcgactt
    24901 taacatccag accgttaaga aggtcttcct tgttcaaaac cacagcagac aggctcaaaa
    24961 tttctgtcgt ttctgtagaa tcgctatcac caaaagccaa agttcgtcca tctaagcctg
    25021 tcatcatttg aatataggtc gccatctttt ccagcaactc tcggtaacta tcttgcaagt
    25081 ctggaagcaa gagacacaaa tccagcaagg ctttataaac ctctacatga tagagaatcg
    25141 actgttcaaa ctggcttcca tctcctaaaa tctgtgtctc aatttgctgt ttcaactcct
    25201 ctgaagcaaa atggtaagct tcttctagat ccatcttatc tgaaaagaaa tgatagatag
    25261 caagcatcgg aattgtttgt aaaatccccc agttactaag ggtgtacttg gcgcgatagt
    25321 agcttttcat aaagtcaatc tgcttttcta gactgaccaa aattttctct aattctttct
    25381 cctctagcaa gtcaaatttc aagaggagca agagtagttt caaccaagta aaggaacgaa
    25441 tacccgtatc caaggttcta gtcatcaagg attgaggaga aaattctctc acctgctcaa
    25501 tccaatcaaa tagaaagaac ttgcactttt gaatatagtc cttatctcct tctaccagat
    25561 accctatcat aaactgcaag agatattctt gtcgattgag catataagac cattctggat
    25621 catcttcaaa tacttgatcc cataccatcg gctggatttg atggattttt gaacaaggct
    25681 ccatatccca aggactatca aacataaaac gattgtccat caagcgttca agggaactct
    25741 tgactttctc atagtctttt gaacagtggg acaagatata atcacgacat tggtttccat
    25801 cgactctttc aaaaaattgt cttctttctt ctttcattat ctattaccag aaaaagaact
    25861 acttaaaaag cagttctttt gtctttccca ttacactttc cttttctaca tagatgacca
    25921 caccttttgc aatctgcaag gagaccaagt catctttgat agaaatgatt tttccatgaa
    25981 ttccagacaa taacaacact tcatcaccag atgttaaaga agctaaatac tcttgtcgtt
    26041 gctccatctg tttgcgaagc aacttttgct gacgaataga atgaaagctt gacagtaaaa
    26101 ggggactcac tgccaagaca atcactattc cataaaacaa tgttgtatcc attaagctat
    26161 aatcttaagc cagcttccga taattccgat gataactgtt aaaataacga gtttatatgt
    26221 tgtccatttc ttttctttga tcaagtagta aactaaaagt gtaaataggg ctggtagaag
    26281 agctggagca accttatcaa gcattccctg aatacttacg atactttgtt tagcgtctgc
    26341 tttaacttcc cctgcagcaa aggtaatcgg caccataatc ttaacagatg tcgctgccaa
    26401 accagcaatt acggttacac cgataatatt ggcaatacga gaaatcgttg ccatctgttc
    26461 gcttagttta tcaatcacag ttgttcctag tttgtatcca tacagaccag ttgacaattt
    26521 aatcgctgtt aaaatcgtat tcatcgcaag gaagaacaag attggaccga caaccaagcc
    26581 ttcttgagca aacgaagctg cgatggttga gaacaatgga gctaaacaga attgagaaag
    26641 agaatcccca atacctgcca atggtcccat caaggccatc ttgatgctac gtgtttcttt
    26701 tgttggtcgg ccattttcca acattacaag atgcaagctg gtaataaaag gcaggaagtg
    26761 tgggttggta ttatagaatt cacagttttc ttccaaggct tggtagaaac cttcctgatc
    26821 ctctccatag tgttttttca aagcaggata catcacattg gcatatccca acccttgata
    26881 gttactatag ttaaatccat tttgacaaaa gaatgcccgc aaagacgttt taagataatc
    26941 acgttttgtt aatttgttag atccagtcat cgtgtgcttc ctcctctacc acatgatccg
    27001 ctgtttttgg cttgttataa aattcaatca aagcaaagat agtacctaca attgcaatac
    27061 caattgttgg gatgtttaga taagctgcac aaacatatcc caacaagaca aagggaatca
    27121 actctttctt agccatcact gacaagatca tcgcaaaacc gatagctggg agcattttac
    27181 cagcaactgt caaacctgta agcaatactg gtggaatgta gtctacgagt ttcaacaagg
    27241 tatccattga aagggcaccc aagcaaccca aggtaaatcc aataaaggca aacaaccaaa
    27301 ttgttgcatt tagagtgaac ttgaatttct tcaaattatg gtttttcaag tgcttcatcg
    27361 ccgtttcagg cgcaccagca cgtacagtgt aggcgaaagt ttgtaagaat tgaatcgcca
    27421 cagcaatcgg agtagagagg gcaagagccg cttctggact gactttacca gcactagtga
    27481 tagccatcaa ggtaccaaag ataccaggtc cgattgggtt tggtggaaca gtacctccag
    27541 caccaacacc gaatcccata taagccaatt caccaatagc tcccattgca agagcagtag
    27601 gcaaatcacc tagaataatt ccgacaccaa atgacagaac aatacatcta ttggtgtaaa
    27661 ttcctaacag cattccacta aaacagaaag ctgtccataa tccaattaaa atcgcttgaa
    27721 atacattaat cgacataacg atctcctctt ttaaatatag tccataatgt tgacttgaac
    27781 agctccatca tttcctgttg gagttgtttt cgtattaaat gttacttgat gagtttggct
    27841 caattccttg agggccgcct tgtcctcttc acccaggaag atggagcgtg tcacttgctc
    27901 tttaccagta gcattgtgaa tgttcccaat attgatttct ttgataggga caccaccttc
    27961 taccaaggtt aaagcgtcct tcacatcctt tacaacgata aagatcgttt gagcaggatt
    28021 agccttgtga atgatatcaa tcaccttttg caaagggaag aaacgcatgg caactgagtc
    28081 tggcacaact gttttcatca gagtttgttg catcttgtct gtgcttactt cgtcattggc
    28141 aacaatgacc gtattacaac ctaggtattt tacccaaagt tgtccttgcc catgaatcaa
    28201 ccgttcatcg atacgggtca taataatatt tggcattgtc atatttctcc tcctaccaat
    28261 ataggttcca gtctttgtag aaacggataa gggcttctag gtaatagtag tcaccccaga
    28321 tattgccttc atccactcct ttacctgaat gccatgagta cacaccgtgg aggagacttg
    28381 tcccaccagg ggtaaattga tcatttgcat aatgttcgat caaggaacga agcatggcat
    28441 gcatagcatg tttataaata tctttgtcag catccacctc tgggagatgt tttagcattt
    28501 catgaatccc acagacggcg atagctgttg ctgaagaatc tcgtgattga tcactaccat
    28561 cattaaaaat caaatcccaa taggacacat gatcttttgg cagacgattc aagaaataat
    28621 tggtcacacc cttaaacaag tcaaagcagg actcgtcttt taagtgacga taagtcaaag
    28681 gaataccata gactccccat gattgaccac gtgcccagca tgaatcatca ctataccctt
    28741 gtctcgttac acctttaaag ggttgacctg tctcaggatc aaaatagaag gtgtggaagg
    28801 acgaagcgtc atcacggatt acattattag ctgaagcata gaaatggctt tctgcaatat
    28861 cgtagtattt ttgatcgcct gtttcttgat aagcaaagaa taagagttgg atattgagca
    28921 agcagtcgat aatcaaacgg taatgctctt tcttgcccaa gtctccccaa gcttgaataa
    28981 aaccaccttt ttcttgatag cgttcaatca acttatctgc agctttcaag gttgcttctc
    29041 tagcctctcc atctccattt atcttatatt cagccataca agacggtgtg tacaagaagc
    29101 cgagatcatg atgatccaat tctactctct tattgacacg atccaggaaa gaaagaacat
    29161 ttttatgagc gatgttttta aatgcatcct gttgactgta ttcataagcc aaccacagtt
    29221 ctcctgtcca gaaaccattg gtccattccg tgttatccat gattggatag acattatcaa
    29281 aggtagctgg cgtcgggaaa tcttccttga aatagtcaag gttgagttct aactgccgaa
    29341 taaccttatc gattgcctgg ccgacttctt ctttcgtcag aagtggtact tctaagaagc
    29401 gctcaggcga ttttattttt tcaatcgtaa ccttttttat cattctttta ccctttaaat
    29461 acccgattcg aaatcttctt cctcttcctc tgcatccgtt gaaaacaatt ctttaccatt
    29521 tacgactccg ccctgggccg ccactactga tttattaaca acctcatcaa agctatgagc
    29581 cattctagca aagactgctt ccattaacat ggctaagttc aaacccgaga gaacattcat
    29641 tgttttgact ggattttctc ccattatggt agaagaaacc ttgaatggcg atcctcccaa
    29701 gagatcactt aggattaaaa cttcttcttc atttgaaatt gcaagtaaga ttttttgctt
    29761 gagttcatct gctgacattc cttccacaaa gtcaatcgcc tccacatttt cttgattgcc
    29821 tgcaatcaat tgtaaagaac tataaatccc tgtagcaaaa tgtccatgcc ctacaagtac
    29881 aattttcatc ttttctcctt tcttgtttag gtttaccggt ttactttata ttccccattg
    29941 taatccttta tttttatctt gtcaatagtt tttttaaaaa aatattagcg ctttcattat
    30001 ctttttaacc attttaatag acagaaattt caaaatcttc catttttaag gaaaataaat
    30061 ctttttataa ataaaaatat ttatttattg acaaaaccgg tttactagaa tataatttgg
    30121 ttatagagaa gtcttaacaa atttgaaagg aagtatcaaa tgacaaatac atcattctca
    30181 attgagcagt tttctttaaa aggaaaaatt gctctcatca ccggcgcttc ttatggaatt
    30241 ggatttgcta ttgccaaatc ctacgctgaa gccggcgcta ctattgtctt taacgatatc
    30301 aatcaagatc tggtcaataa agggattgaa gcttatcgtg aagttggcat cgaagcccat
    30361 ggatatgtct gtgacgtgac agacgaggac ggtatccaag ccatggtcaa gcaaatcgaa
    30421 caagaggttg gtgtcattga catcctcgtt aataacgctg gtattatccg ccgagttcca
    30481 atgtgcgaaa tgagcgccgc tgatttccgt aaggtcatcg atattgactt aaacgcacca
    30541 tttatcgttt caaaggcagt tattccttct atgataaaga aagggcatgg aaagattatc
    30601 aatatttgtt cgatgatgag cgaactggga cgtgaaacag ttagcgctta tgctgctgct
    30661 aaaggggggt tgaaaatgtt gacccgcaac attgcgtctg aatacggtgg agccaatatc
    30721 caatgtaacg gaattggacc gggttatatt gccactcctc aaacagcacc tcttcgtgag
    30781 ttgcaagaag atggttctcg ccacccattt gaccagttca tcattgcaaa aacacctgct
    30841 gcacgttggg gaaatcctga agatttgatg ggccctgctg tctttctcgc tagtgatgcc
    30901 agcaattttg tcaatggcca catcctatat gtagatggcg gtatcttagc ctacatcgga
    30961 aaacaacctg agtaaaaata gaaagaagat cttatgaaaa tcgcattaat caatgaaaat
    31021 agtcaagcta gcaagaatca cattatttac gatagtctaa aagaagcgac agataaaaaa
    31081 gactaccaat tatttaacta tggtatgcgt ggagaagaag gagaaagtca attaacttat
    31141 gtgcagaacg gactaatggc tgccatcctt ttaaatacaa aggcagttga ctttgttgtt
    31201 accggctgtg gtacgggtgt aggggctatg cttgctttaa acagcttccc tggtgttgtc
    31261 tgtggtctag cagtggaccc aactgacgct tacctttatt ctcaaatcaa tggtggtaac
    31321 gccttgtcta tcccttatgc caaaggattt ggctgggggg cagaactgac cctcaaattg
    31381 atgtttgaac gcttatttgc tgaagaaatg ggcggtggct acccaagaga acgtgtaatc
    31441 cctgaacaac gcaacgctcg tatcttaaac gaggtgaaac aaatcaccca caatgatttg
    31501 atgaccatcc ttaaaacaat cgaccaagac ttcctcaaag acaccatctc tggcaaatat
    31561 ttccaagaat acttctttga aaactgccaa gatgatgaag tcgctgctta tttgaaagaa
    31621 gtattagcca agtaaagcta ttctaaacca gaaaggaact aatggatgac gaaaatatta
    31681 ctgtttggcg aaccattaat tcgaatctca ccattagatg ccaccagtat cggagatcat
    31741 gttgccagtt cgacttattt tggcggatca gaaattaaca tcgcttgtaa tttgcaagcc
    31801 ctgggtatct caacgaaagt ctttaccgca ctccctgcca acgagattgg agatcgtttt
    31861 ctcacattct tgaaacagca ccaaatcgat accagttcaa tctgtcggct tggcgatcga
    31921 atcggcctct actatttgga gaacggcttt ggttgtcgtc aaagtgaagt tttctacgat
    31981 cgtaagcata cgagtatcag ccagattcgg ccaaacatgc tagatatgga ttctctcttt
    32041 cagggaatta gccattttca ttttagtgga atcaccatag ctatcggtca agaggtccgt
    32101 gcgatccttc tcctactctt ggaagaagcc aagcgccgag gaattgtcgt ttcaatggat
    32161 ctcaatctga gaacaaagat gatttcagcc ctagaagcca agtatgaatt ttctaagttt
    32221 gcacgtttta ctgactattg cttcggtatt gatcctctca tgattgatga ccaaaatcta
    32281 gagatgtttc caagagacag tgctagccta gaagaggtgg aaaatcgcat gcgactttta
    32341 aaagaaacct atggtttcaa ggctattttc cataccctcc gatctagtga tgagcaagac
    32401 aaaaatgtct atcaagccta tgctctggaa gaacgatttg aagagtctgt ccaactaaaa
    32461 actgcagtct atcaacgaat tggtagcggg gatgccttta tatctggtgc cctttaccaa
    32521 ctactccatc attcctccct aaaaactacc attgactttg cagttgcgag cgcaactctc
    32581 aaatgcactc tttcaggaga ccatctctcc acttccgcaa ctagtattga aaatttactg
    32641 gcaaatgcac aagatatcat tcgttaggag aattacatga ccaaatcaga tacgattatt
    32701 gaactaaaaa aacagaaaat tgtcgctgtc attcgaggaa atacaaagga agaaggacta
    32761 caagcctcga ttgcttgtat caagggcggt atcaaagcta ttgaaatcgc ctataccaat
    32821 cagtatgcag gacaaatcat caaggaactt gtagacttgt atcaggacga tcagagtgtt
    32881 tgtatcggtg caggtactgt gcttgatgcc gtaactgcta gagatgccat tctagctgga
    32941 gcaaattacg ttgtttctcc atctttccat gctgaaactg cgaaaatgtg caatctctac
    33001 agcacaccgt acattccagg ctgtattacc ctcacagaga tcacgactgc acttgaagcc
    33061 ggtagtgaaa tcatcaaact cttcccaggt agtactctca gtccagcata tatctctgca
    33121 gtcaaggcac cgatcccaca agtttccgta atggtaaccg gaggagtcgg cctaaacaac
    33181 atccctcaat ggttcgctgc tggtgcagat gccgttggaa ttggtggcga actcaataaa
    33241 ctcgcttccc aaggcaactt tgaccgcatc agcgagattg cccaacagta tattacactc
    33301 agataaaatc ataactaccc gtctaacggg tggtttatcc cagagctata agcccaaatc
    33361 atcagccagc gcctaaagac gctggctttc acgttgttca agccttattg ctcttgactc
    33421 gtcacttgcc tctttaagag actttggtat tacttaccac tatccctaaa gggatcctca
    33481 tattctttta cactcaattt atctagtgct atagtagatt gaaactggaa tagtatacct
    33541 ctacttctaa aacattgtta aaaatcgatt tgactgtcct gatcgatttt gtcctgttct
    33601 tatttcattt tactatatat catactttac tagttctcaa attttcatac tcgtgaagaa
    33661 atcatccact cgataatttc tttaatcttg actatatttc ttaattgtgg cttcattaag
    33721 ccctactgga cttacataat aaccttccac ccagaaatgc cgattcccaa acttgtactt
    33781 gagattggcg tgtttgtcaa acatcatgag tgcacttttt ccttttaaat aacccatgaa
    33841 actcgaaaca cttagcctta gtggaatact gactaacatg tgtacatggt ctggcattaa
    33901 gtgaccctcg atcatttcaa cacctttata actacacaag cgatgaaata tttcgcctaa
    33961 actacttcta tattgattat agatgacttt tcgtctatac ttaggggtga acacaatgtg
    34021 atagaacacc tccactttgt gtgagataaa ctatgagcct tttgtgccat attttttctc
    34081 ctttcgcttt acaagtggat tgaacacctt tattgtatcg cgtttggagt ttttttggta
    34141 taaccttcga cgcgcacccg catagcgggt ggttgttttg tctcgctccg tgaggtgcga
    34201 gacggactaa tatagtagag tgaaatagga tacgaataaa ttgattagga aaatcaaatg
    34261 aatttataga aatcttttag cagttatgat gtcctattct agtttcaaaa cgctatagtc
    34321 acataatgaa gtaaaaagga taagtatcaa cttatccttt tttaaaagaa aaatccgaag
    34381 atatttggcc ttcttcggat tttttctatt ttccacagtt tcatgtaatt catctagatg
    34441 atgaacaaat tagttgttct ttcctctacg gaataaataa aacgccccaa gtagcaagaa
    34501 ccctagactt gccaagattg actgaccttc tcctgtctga gggagattct tttgatccga
    34561 atggttcttt tcctcttcag atttttcctt ttcttttgaa ttctgtactt gtggctgagc
    34621 tgcttgctct agctttttaa agacttcctg atctggagct gattcctggg tttcaggatt
    34681 atagtaggca atcttatatt catccccttc ttttcgaatg gtatagactc cacgtttcaa
    34741 aacttggaat tggttggaaa tagtagagac agaatcatca tatttcacaa tgccccaaac
    34801 tccttgtttg gcatcataaa cagactgaag ggtttcgtta ttttcgatga ggctactttc
    34861 taactctttt atcatttgat tgaaggtggc acgacccacg ttagggatga gcatatagcc
    34921 ataagaatct ccattttgct tatgagcctg actaatcgta agaaattcat tttcaacttc
    34981 cttgtctgac tgtccttcat tgatatcctt ccaggctccc ttttgcaaag ccttactcat
    35041 actgattgaa ctcttcttaa agaaaaagta accaatattc tttttcgaat cggatgattc
    35101 taaaaagaca ctttgggttt caggataatc cttttcttgt tctgtaaggg aggcttcttt
    35161 atcattgaca tagactttat atggattact tgattccagt tttctctggt caattgtagt
    35221 tgcagcagta tctgttgaag tgttttggat attgcttcct aaaaaggcga tcttatcctt
    35281 tagcataaac cagctcttat gagcagtcaa tgtttgattc cagttggtga aatccatggt
    35341 tgctgtcgca ttggcatcat ctagtttgct cgttccaacg aaagcagacg gtaaaacttt
    35401 acctgtatcg ctatccgctc tcttagcatc cgtctctgtt gtaccaggca tcttatatgg
    35461 attaactgtt ggccagtagc catcgctata gtgactcaaa tcgccattgt aaagatagaa
    35521 catcccatca ctcgtatacc aaccacgttt attttccttg ttcatgtgtt cgtaattcaa
    35581 ggtacgactg gaaaagagtg acaagccaaa tccaaaccct ttctctgcat tgtacatggc
    35641 tgttttatcc atcttgttaa aggcagatag gtaacttgtt cttggaacac ttgcgactcc
    35701 tgcatcactt aacaaggatt gcatcaaact gatatcctta taagtcttca aattcttaaa
    35761 gacatcataa taactatccg attgaacaat ggtcttcaca agactctgca aacgttgttt
    35821 ggtttctcct tcagacatat ccgctattcg gtgaatccct cttagtactt ctactgcggc
    35881 cacgtgcccc tcgctatttg cacgactgat cgagcgtcca cgactcatat ccatcagctc
    35941 tccattcacc agcaaaggag caaacgattt atcaatccag tggtacatgg tttgcatttt
    36001 atctttatcg attggattct tggtcttttg aatgactggc aacagttgag acaggccatc
    36061 aatcaaaaca ttcccataag cacccgtata ggcaacattg gtatggtcga tataggatcc
    36121 atcttgataa aaaccttcac cttggtctac caacttgaac acttgctcaa tcgagcgaat
    36181 ggtagaagaa atttcttgat catccttacg cagtaaacca gctattactt ttactcttcc
    36241 catatcaact aagtttccac ctagagcctt aaatgggtta tcagtcgtct ttcggaaatg
    36301 ttcgggatct ggtacaaatt tttcaatcac atctgtatat tttttaattt cctcatcaga
    36361 gaagtattct ttcatcagag acaaggtatt gttgatggca cgaggtgtac cgatttcata
    36421 atcccaccag ttcccaacaa tgctcttttc actattgtag acatgtttat gcatccattc
    36481 catggaatcc ctgactgttc gaacgacagt ttcatcttga taataacgag aaaaaggatt
    36541 ggtcacttgc ttggccatct cctccaattt ccgataagtg gcagtcagat ttgcagacat
    36601 tttataattt gaaaattttt cccacaaata ggtgcggtcc gcctgacttg aaatactaga
    36661 taggctatca gctacctttc cttccaattc ctggtttaat ttggccatct gttcattttt
    36721 agaatcatag tattgattcc cagcgatgat gccattccag tcatccaaac ggtctgtgta
    36781 tgcatcctta acagaggcta gaatcttcaa aggaatcttt ttcacttcct tgccatcttt
    36841 actgacaatg acattggttg tcccttcctt aagaggttct aaaattccat ttttgactga
    36901 agcaacgtca ggattttcta ccttataagt atagtccgca agagaaaaaa catgtttttt
    36961 tccaattggt aaatcaatct tttcctcaag ctgtttatct gtttgatagt cctcagaagg
    37021 ctggtctgct acctctacca gctcaatatc cttaaaggaa acagtcccag ttcctgtttc
    37081 atagaataac tccagcttga ttttatcaac atctaaagtc gggctatagt ctgcttcaat
    37141 ggtctgccag tcctttgttc ctgacgtcgt tgcagaattc cacaatcgct tgtccttatc
    37201 actttcctca atgatacgaa ctttggcaat cccgacttta tgatctgttt taatcttgaa
    37261 acgcagttta tactttttct tagcttcaat aggaaccata cggtgaaccg ctgcccttaa
    37321 tttctcatgg cttgagatag tgatagcccc atccttagcc tcaatgactc gagttgaggc
    37381 atctgcacta ttcttctggt ctacccaagc tgaccacccc tgagctttgc ttcctgtcca
    37441 cggactgctt ccgtcctccg tctgaccaaa atcaccattt tcaactaaat tttttgtatc
    37501 cctttgctga tactgaactt ccttctggct ttgctgaatg gtattcgtag tcgtttcttc
    37561 cgctccaact gtcatataat ggtttaataa aaatcctgat aaaacaagtg aagacaaact
    37621 cacaatgagc ttctttgttt ttgtttgcat gtatacactc caataaacat attgtaaaat
    37681 caataggaac taaatctcaa attagagatt tatagcaact aagtaaaccg gtttaattaa
    37741 atcataccat ttttaaagtt atttgtaaac ggtttctatc atattgaagg cttattcttc
    37801 aacaatatct tccatccgac tcgacgaaaa aagtaaaaac tgttacaatg tagaaaaaga
    37861 aaagaggccc tcatgacttc actttatgat ttttccgttt tgaaccaaaa caaccaagca
    37921 actcccttgg atagctatcg tggcaaagtt ctcttgattg tcaacactgc tactggatgt
    37981 ggtttaacgc cccagtacca gggacttcaa gaactctatg aacgctatca agatcagggc
    38041 ttcgaaatat tggatttccc ttgcaatcag tttatgggac aagcacccgg cagcgcagag
    38101 gaaatcaacg ccttctgtag cctacatttt caaaccacct tcccacgttt tgccaagatt
    38161 aaggtcaacg gtaaggaagc agaccctctc tatgtctggt taaaagacca gaaatccggc
    38221 ccactaggaa aacgaatcga atggaatttc gctaagtttc tcatcggtcg agatgggcaa
    38281 gtctttgaac gcttttcttc aaaaacagac ccaaaacaaa ttgaagaggc gatacaaact
    38341 ctactataat tcacaatctc actatgatta ggtttccttt aacctgatga atagtgagat
    38401 tttttgattg gctttgactt aaatagaaaa acaccccatg atatgaaaca tgaagtgttg
    38461 taaagtctat gttgtaggtg cttatttcac attttcaatg tgaccagtga taacgaatac
    38521 catacagaat cttcatatac actaaacaaa tgactttcta attatatcaa ttagttttgg
    38581 ctagtaaata tcatttccaa caaacgccct ctcaattcct tatcctgatg atgcaagata
    38641 ttcattaagt catgagagtt tttcgcattg atgaattgat ttaacaatct atcttttaat
    38701 tcatatggaa gagaagctgt ctttagtagt ctaaaaactt catcatttaa agatattgtt
    38761 ttattatctt tacattcaaa tctagctgta tcattcttat ttggtaattc aattatagac
    38821 acattcgttc ctttaaaatg aattctatgc cttctattgc ttggaacgat actagaatct
    38881 ccttgtaatg ttaactctac catccccatt tcccaatcga ttgataatct tgttttatat
    38941 ctttgaccat tttgatcttc aagcatttca aaagaatgtt gtttgcctgg gaatacatac
    39001 caatctacaa cttcaggtaa atcaacaccc atatctatct cagaaccaac caagggaatg
    39061 atcgcaccac tttttgcaaa cacaggtata gtcgaaatgt ctctataaac actcaacttc
    39121 acaccacctg tatatttttt ctctgaaaag aagtcatacc attcaccttc agggaaccat
    39181 acatccactt ttgcagattg gaatgccaag tccatctttt ctacaatggg agccaccatt
    39241 agttctgttc caaaaaagta ttggtttgga acattatagc tctcatcatt ctctgggtag
    39301 aaataataca ttgggctgat taatggggca ccttcctcgt gtgtctttac attcatagtg
    39361 tatagatatg gaatcatctg atgcctcaaa cgaaggtatt tcttcataat cttagatgtt
    39421 gtttctgaaa aaaaccaagg ttctttacta ttaaaaggac ttctagaact atgtaatcga
    39481 gtgatcggac taaaaacacc aaactgtagc catctagttt gcagctcttc gtcataatcc
    39541 cccagcatgt gcccaccgat atcatggctc caccaactat aaccgatatt tgatgctgtc
    39601 gctgtaaaat aaggttgaaa tcttaaggaa ttccaactaa taatagtgtc ccctgaaaaa
    39661 ccaacagggt agcggtgact accaggacct gcatatcttg ataaaatcaa accaccttct
    39721 gcatttttac aactatcctg atagtgataa tgatttaaaa gccacagtgg atccaacatg
    39781 ccttgagtcc cctgttgcca gtcaatccac caaaaatcta ctccctgctt ttctagctta
    39841 taatgaacat ctttaaagta ggcttctcta aaagatggat taaaaaaatc aaaaatagca
    39901 ggttcttcta gttctacatt taaccccaat cgttttgcga cttgaggata agcttcttca
    39961 taagcccgta taccatcagc aggatggaca tttaaggaga gtttcaactt tctatcatga
    40021 agttgttgca ataactgttc tggattaggt attaagtttt tattccaact atatcctgtc
    40081 cagccacttc caaaacgagc tggaatgtca gttatatgcc aatccatatc taaaacaccg
    40141 atagataatg gaacgttctc tgtttcaaat ctgtctatta aatccaagta ttcatctgac
    40201 gtataaggcc aatacctact ccaccaattg cctaaagcat atcttggcaa caagggtgtt
    40261 gaaccagtca aatggtaaaa gtctctgatt gctcctctat aatcatgccc ataggcaaag
    40321 aaatagagat caatttgatt ttctctctca atataaccag actgttcatc ccaaataaat
    40381 ccttgagaat catccaataa ggctatacca tttcggctaa taattccatc ttctaacgag
    40441 attgctccat ctgcctcatc cagagtccga gctgttcctt ttaacgtttc aatagattca
    40501 ccaaaatacc agcgactacc atatacggca aaatttcctt ttaattctat aaataaattt
    40561 tcggcgttaa attctccttt attaaaatgc aaatgaaaat agtccgtcat aatatctagt
    40621 acgtttgatg tctcgatata atctaacgaa acttggacaa aatctctatt atagataagt
    40681 tgtgtcgttc tatcctcaaa acttccagtt tgagagtatt ctaaccttac taacttgtct
    40741 gttaatacag agattcgata aaactctccc ttaaaaattt tcaatttgtt tccctccttt
    40801 tatggtagca taaaaacaga acgcaccatt tttgatgcgt ttttcattat tctgaatgca
    40861 atgttctatc tgttatatct atgacaaata atagtcaatt gaaaaaatgt agtggacaaa
    40921 atatctttta acaaaccaag agtttattaa agagttatca cttttcaact tttctaagct
    40981 tatgcagttg tgaaacaaac tacttttaaa ctattaacta agataggatt gataaataat
    41041 ttcaaactct tactagcaat catacgatat tcaagctcgc gtgctttttt ccttcctgct
    41101 tatttcttag aactgaagaa cccggatcgg tatataaatt atccggatca acatagtcat
    41161 aagattcata acagttgcgc ttcattaagt catccccaga gcaagagctt catctcgtaa
    41221 tttttcaaca tcactaaccg taggtcgcca tccttcaatc atatttgtac ttaaagcata
    41281 ccaaacactc ttaaaaacgg atcggttttc aaaagctatt cccatgattg tcatcttttc
    41341 tttatctata tctaaggaca tatgctacct cctttagata cattatacca tgtttctctg
    41401 tagcttttaa aaattttatt ttgtttgtca tatctaagtt ttcagcacgc ttatcctatt
    41461 ttataaacct caaacccaaa tataaaacgc attctttttg cttttttact attgtatcgt
    41521 attctacgat aacatacttt actttattgt ttttttaaat aacagcagtt ccctgtttat
    41581 caactattcg aactactttc tattttgctt cataccctac atagcgaaaa aatatgaaaa
    41641 agcagagaag aatatcttaa aaagacctct tcactgctaa tattaacact cattatttaa
    41701 actatatgga ttctatcatc gagtatactt ttttacttat tagatacctt gctcttcttt
    41761 caccaatttt tgatcatata cacggatgaa tggaagatag actaggaatg ctgcaaatgc
    41821 acatactaga gcaactaata cagctcgaag atctgctgtc cctaagaaag ctccaatccc
    41881 tactggagtt ggccatggaa cctgtgcgat aattggctta ataaagttta gagaattcgc
    41941 tacgtaataa atagtagcag taaccattgg tgctaaaata aatggtatag ccaaggctgg
    42001 attatagata ataggtaatc caaaaattaa tggttcatta atattaaata aggccggaac
    42061 tacagatgct cgtcctattg ctttaagctg ttcagattta gaggcaaaag caatatataa
    42121 acatagtcct aaagttgcac cagaaccacc tgcaattaca aacatattag aaaattcacc
    42181 tgcaacagcg aagtgcccgc cagcagcatt ttcagccatg ttagcaagag caattggact
    42241 aacaaatgca aaaacaatgt tcgcaccgtg gatacctaca atccaaagta gttgagtcaa
    42301 tagataaata atcattaaac caatccacga attagtcaga ttggatacaa aaccaaatgg
    42361 aattgcaatg actttaaaaa tatctgttcc cattgctaca agaagaccgt tgataaagat
    42421 aacaacaaat gcaacaacaa atcccggaac caaagcggta aatccacgag aaactccttc
    42481 tggaacagct tcaggcattt taataaccca attatgttta acacacatac gataaataag
    42541 aacagtcaca attgccataa tgattgcggt aaaaatccct gttgtcccaa aacgtgcgac
    42601 tccatttccc attgcccatc catctgcaat tactgcacct tcttttagac ttgtcacagt
    42661 cttcatcatt ccaccatcaa aaatgatttg cggtactgtc atgacaaaag ccatcaaggc
    42721 gagcaaggca ccattaagag gattcatatt gagttcttct tcctctgcat aaatttttgt
    42781 caattcatat gcaagtgata gaacgaaata aagagataga gaacccatag tcgcatagtt
    42841 tgcaaccatg taaagtgatg tgaatttatc aaatgaagca gagaaaatat ctgccacaat
    42901 tggccaaaat gagaaagctt gtggcaaaat actgaatacc aaaaacattg atcctacaat
    42961 agtaaatggt acagcagcca tacctgcagc cgtgatagca cgcactactt taaactgagc
    43021 aagtttgccc attggtccca taacatggtt ttcaagaaaa ccaaacaacc cgttttgttg
    43081 atccataaat agacctcctt aataaaacat aataattttt actttctaaa gactagtttc
    43141 aaatacaaat tatactagat caggattata aactaagtga gttcttttcc aattggacaa
    43201 attgttgata agccttatct gttcgtttat aaattttttt aattcttcta atgtctaaca
    43261 aactcagaac taaacctaat agaagaacta caaaaacaaa taaacgtgct acttggttat
    43321 tttcaaaaat cggaaaaaga ttcttaaacc aacttgtcca agttaaaaca agtaatccta
    43381 ttgaaataag catttgtatt ctaacaaaca ttagtgttat tcccaacttt tctttcctat
    43441 ttccataaag tttaaattgt tcaatagttg ctaaaataga aaatactatg agcataatgg
    43501 ggaaaataat aataggcgag ggattaataa actgattcaa aagccaataa atattcccaa
    43561 aaaagaagag agctattgaa taacgtagaa gaagatatcg attaaaaaaa gtattagtta
    43621 gagccatctc tcgacgttgt tgttcaattt tttgtcgttc ttttttatcc atatcatttc
    43681 ctccttatat aacaacacat atttagttaa ctttcttata aagagctaac atttcctttg
    43741 ctacttctaa taatgtcata gtggtcatta aatgatcttg agcatgtacc atgataattt
    43801 caattttaat ttccactcca cttgcgtatt cttgcaagag tttggtttgt gcatgatgcg
    43861 cttcaagaat tatctcattt gattgattta atttactttc tgcatcatca aaactacctt
    43921 ctctcatttt tgcaaatgct tcatgtattt ctgaccttgc atttcccgaa tgcaggataa
    43981 tttcaaatgc tgcaacctgc agttcctctt gattcatatg aacctcctat tttatcttct
    44041 caaatatgtt gataaaatct tcaaagttat tgcaagatat tagctgattt tgcaattcat
    44101 cattctctgt cagagagact atctttttag tcacagttgc taaaccttcg ttcccatata
    44161 ttgatggaga tagaagaaat actagctgga catgtgaact ttgattatcc cagagtaacg
    44221 aatctttaca aattgcaacc gaaacctttc cctctgtacc aaagggctga ataggatgcg
    44281 gaactgcaat tttttcagaa aaaacaactg aacttaattc ttcgcgctgt ttaattccat
    44341 aaagtaaaga ttgttcaaac tcatttgatt caccaacaga taaaccctca accatctttt
    44401 caagtaaatt taccttgtct gattcagtac atattaaaaa attttcttta ctaaaatact
    44461 gtctaaagcc gttgttttca aatttgttaa tctttgatga ttgtacataa ctagaaactt
    44521 gcatctgatc catagctttt ctaatcattt ccatctcatc acttttaaga aacacactaa
    44581 ctttaaaaac tgggatttga aaatatagat ttgataaatc aacagctgac actataaaat
    44641 ctattccttt aagtttttct tgattcaatt catagtagcc tattacatca acaacttcta
    44701 ctcgcttccc aaactccgtt tccaaacgat ttcttaacat ttgggctgca ccaaatcctg
    44761 ttgcacaaat agcaagaata ttaaacttag tactctcttt gctacgttcc atagcagcta
    44821 aaaagtgaag acttacatat gctacttcat catctgatat tgtccactcc aagaacttgt
    44881 ccatatttgc aagaatttct ctagtcataa agaatatatc actataattc tgtttaattt
    44941 catctactaa agggttattt aaggtaatcc ggctttctaa acgtacttgt agtgtcatta
    45001 gatgagttat caatccttca attagttgga aatctgaaga aaagttatac atatcatcta
    45061 atcctaaatt ctgaaatgtt ttaaataaag atttttttaa aacttcttca gaaatattct
    45121 tctgattttt ttgacattgt tgactcttag ctaacaaatg caaagtaatg tagtctattt
    45181 cctgaactgg aaattcctga tttgttactt ctcttacttt agaaagaatt ctttgggcaa
    45241 cctttctctc tgttgcatca tcagtcatct gacagtctat attttttatt tcaaatccgg
    45301 attttaaacg aatcacagac aatgctatgt gaactactaa attctgtagt acaaaatcag
    45361 atagttttag gttggcctct tggcattcat ccaaaacaat tctagcaaat tcttctaatg
    45421 gaacagtttg atcaaaaaag ttaaatttta catagcaatg tattgtttta aaaaattgat
    45481 tctctaggaa ataatttatg ataaaacgtc gtttatcacg ttcctcgcct gagacataaa
    45541 ctcctttatt cgccctactc tcaatggaca aattatactc tgataacatc actcgtatct
    45601 ttctgaaatc atgagataat gttgaacgac taacgtaaag ttcatcagct aaatcatcaa
    45661 aaagaactgg aacttgctca aataataatt tatttaagat aaatactaaa cgatcatcac
    45721 cttttgaaac cgcagttttc gtatagtctt cttccagttc ataagtttgt ctaaactcct
    45781 ggtaagcgcc ttgattctca aaaaatattt gatacccttg accttgtttt gaaatcaacc
    45841 ggactccttg aataatcatt gtcttctcaa ttaatttcag tacattacgg acagttctat
    45901 ctgaacagga taaatattct gctagttctt tgcttgtaac aaaacgttcc ttatttttta
    45961 ttaaaaattg aaggatatct ttctctttaa tgtttaacac attcattccc tcctaaaacg
    46021 tatgttttca tatattgaag catattatac acttaaatca atttatatca aactcaaaac
    46081 aatttatctt aacttaaata tttattgaca tttcatgtgt tcatcaaata ttctcaagaa
    46141 tcaaattagc cattttttca attcccattg gaataggaat ataggcttga ggaggtattt
    46201 gtacaactgg ttttcctgct ttagaaccag cctcttcaaa ttgcttaaag tacatttttg
    46261 tttgaggact gacaagatac aaatcaaaag ctgctgctgc gatagctttc cctccttcag
    46321 tagcactaat agcatcaact acaatatctt tcccttttcc ttttagaaac tctgttgttt
    46381 tctgtgccat aagtgatgaa gacattcctg ctgcacaaat aattaaagct tttgccataa
    46441 tattttctcc ttttcttaaa tccaatcaaa gctgtgctaa gttggcttat ttgttatcta
    46501 tttttattat aaaataaagc gtttccaatg acaattccct cattttccta aatgatatgg
    46561 aaaaaaatta tttatacttc aatttataaa ataaaattat tcctgagagt agaaatgaaa
    46621 cactatttgc taaaatcaaa ggcaagtctc ctatacgaat accatgagca agccacaatg
    46681 caataccaat aacttgcata acatacatac ctagagcaat agagcctgtg tcctttgtct
    46741 taactacacg aaaaacttgt ggtaaaaatg caaatgttgt taaaattgct gcaatacttc
    46801 caatcatatg tcacctcaat atgctaaaca aactgagaat aatctcagtt tgtttatact
    46861 attctactga ttcaccgtta gatgaaataa cttccttata ccagccaaaa gattttttcg
    46921 gggaacgatt ataacttccc ttcccattat catctttatc tacataaata aagccataac
    46981 gtttccgcat ttcaccggta ccagctgaaa ccaaatcaat acatccccat ggagtataac
    47041 ccattaaatc aacaccatct tcaactacag cctttttcat ttcacgaata tgggcatcta
    47101 gatattcaat tctataatca tcatgtacca taccatctgc tgtaacttga tctatagctc
    47161 caaaaccatt ttcaacaata aagagtggta agtgatagtg gtctgtaaac caatttaacg
    47221 cataacgcaa accttctgga tcaatttgcc actcccattc agaagcctta acataattat
    47281 ttttcactaa atcttctgtt tcaagataat caaaataagg attattttca cgatgagagt
    47341 cgatagcaaa ggacatatag taactgaaac caatgtaatc tacagtccca ccaagtaaat
    47401 cttctttatc ctgggcagca aaatcaactg aaataccttt tcgttcccaa tacttgaaaa
    47461 tatgctcagg atatttacct aaaacatgca catcagcaaa ataataacgc ttctgcatag
    47521 ctttcattgc cattaagata tccttaggat tgcaagtagc tggataaatt ggacacatcg
    47581 caatcataca acctatttga aaatctggat taatctcatg accaattttt acagctcgtg
    47641 cagaagcaac taattcgtaa tgtgctgctt gatacataat tgcttctcta ttatcacctt
    47701 cctcatatac aatacctgag ttagtaaatg gtgcaaaatc ttcctgataa ttcgcttgat
    47761 tattgatttc attgaaagtc atccaatatt taaccttatc tttgtaacgt ttaaatacga
    47821 cttctgcaaa acgagcaaag aaatcaatca atttcctatt tttccaacca ccatattcgg
    47881 tcactaagtg ataaggcatt tcaaaatgag atagagtgat gacaggttca ataccattct
    47941 ttaagcattc atcaaaaaga ttatcataaa actgtaatcc ttcttcattc ggctctaact
    48001 catcaccttt tggaaagata cgcgtccatg caatagaggt acggaagcac ttgaatccca
    48061 tttcagcaaa aagtgctatg tcttctttat aacgatgata aaaatctatc gcctcatgat
    48121 ttggataata tttaccctct aaaactcccg aagtaatttc acgagctact ccatgacgac
    48181 cagcagtcat aacatcagca acactaattc ctttgccacc ttcttgccat ccgccttcaa
    48241 gttgatgagc agcaacagca ccaccccata aaaatctatc tttaaaagta gtcatctttt
    48301 ttcctcctga ctttgatact cttattataa accttaaacc aaaatatgaa aacgcattct
    48361 ttttccttat tgttaaggaa agaagtaatt tttaatggaa atagaacaat atcttcttgt
    48421 attctcgtaa tgatatcttt acgattttca atactttcaa actacaaaaa ctctcacaat
    48481 aattctaatt ccctgtgtct ataaacgact tatcgctttc tggcatccca gaatcatctt
    48541 ctatataacg ttcaacttgc atctgcaagt gatatttttt tcttaaatct aagattttct
    48601 gcattgtctt tgattgatga tgttcatcta aagcttcttg atttatccac tgatcaataa
    48661 ggagaatagt tccctctttt tcaattggta aaaaatattc gtatttcaag ttaccttttt
    48721 gatttctaat ttcttcaaca aggccactat caagcatttc tcttgcaaac tttattgcac
    48781 tatctccatc acctttataa tatacatgaa tagtcaatgt catcttatat cctccaaaat
    48841 catccttcaa ttttaaaaaa acaagtttag atgaggatct aaacttgttt tttatgaact
    48901 aattatctaa cgtttcgcca ttactttcaa tcacttcttt ataccaataa aatgattttt
    48961 tcttatagcg at
//
LOCUS       DAVLGK010000009        47999 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLGK010000009 DAVLGK010000000
VERSION     DAVLGK010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.009"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(595..1575)
                     /locus_tag="VXE01_000583"
     CDS             complement(595..1575)
                     /locus_tag="VXE01_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV0749550.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1913..2062)
                     /locus_tag="VXE01_000584"
     CDS             complement(1913..2062)
                     /locus_tag="VXE01_000584"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749551.1"
                     /translation="MKIKEQTRKLTAGCSKHCFEVVDETDEVSSKHRFEVADRTDEVS
                     NIYIR"
     gene            complement(2090..4105)
                     /gene="recG"
                     /locus_tag="VXE01_000585"
     CDS             complement(2090..4105)
                     /gene="recG"
                     /locus_tag="VXE01_000585"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV0749552.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(4124..5227)
                     /locus_tag="VXE01_000586"
     CDS             complement(4124..5227)
                     /locus_tag="VXE01_000586"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV0749553.1"
                     /translation="MKASPHRPTKVLIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(5217..5585)
                     /locus_tag="VXE01_000587"
     CDS             complement(5217..5585)
                     /locus_tag="VXE01_000587"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV0749554.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5624..6655)
                     /locus_tag="VXE01_000588"
     CDS             complement(5624..6655)
                     /locus_tag="VXE01_000588"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0749555.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6657..7688)
                     /locus_tag="VXE01_000589"
     CDS             complement(6657..7688)
                     /locus_tag="VXE01_000589"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0749556.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7769..10282)
                     /gene="secA"
                     /locus_tag="VXE01_000590"
     CDS             complement(7769..10282)
                     /gene="secA"
                     /locus_tag="VXE01_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV0749557.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10428..10715)
                     /locus_tag="VXE01_000591"
     CDS             complement(10428..10715)
                     /locus_tag="VXE01_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749558.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDKPLLGIRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFELICCLSLWINLFITFAILPIFGN"
     gene            complement(10743..11375)
                     /locus_tag="VXE01_000592"
     CDS             complement(10743..11375)
                     /locus_tag="VXE01_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0749559.1"
                     /translation="MKLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(11379..12020)
                     /locus_tag="VXE01_000593"
     CDS             complement(11379..12020)
                     /locus_tag="VXE01_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749560.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            complement(12013..12804)
                     /locus_tag="VXE01_000594"
     CDS             complement(12013..12804)
                     /locus_tag="VXE01_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749561.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFLGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12826..13218)
                     /locus_tag="VXE01_000595"
     CDS             complement(12826..13218)
                     /locus_tag="VXE01_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749562.1"
                     /translation="MKTKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAADMARQNWWDLSAAISGSWSPN"
     gene            13526..14377
                     /locus_tag="VXE01_000596"
     CDS             13526..14377
                     /locus_tag="VXE01_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0749563.1"
                     /translation="MRWDYEQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLSEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKVFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            complement(14599..14949)
                     /locus_tag="VXE01_000597"
     CDS             complement(14599..14949)
                     /locus_tag="VXE01_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749564.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(15089..15424)
                     /locus_tag="VXE01_000598"
     CDS             complement(15089..15424)
                     /locus_tag="VXE01_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749565.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWIYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(15515..16825)
                     /gene="der"
                     /locus_tag="VXE01_000599"
     CDS             complement(15515..16825)
                     /gene="der"
                     /locus_tag="VXE01_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV0749566.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPGMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(16839..17552)
                     /locus_tag="VXE01_000600"
     CDS             complement(16839..17552)
                     /locus_tag="VXE01_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV0749567.1"
                     /translation="MTETIKLMKAHTSVRRFKEQVLPQEDLTEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQTHDVKPRLPLDNVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLKQKKLL"
     gene            complement(17549..18445)
                     /gene="dnaI"
                     /locus_tag="VXE01_000601"
     CDS             complement(17549..18445)
                     /gene="dnaI"
                     /locus_tag="VXE01_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV0749568.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTTWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(18446..19615)
                     /locus_tag="VXE01_000602"
     CDS             complement(18446..19615)
                     /locus_tag="VXE01_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV0749569.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEYLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKEAIIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            complement(19616..20089)
                     /gene="nrdR"
                     /locus_tag="VXE01_000603"
     CDS             complement(19616..20089)
                     /gene="nrdR"
                     /locus_tag="VXE01_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV0749570.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            20229..20594
                     /locus_tag="VXE01_000604"
     CDS             20229..20594
                     /locus_tag="VXE01_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0749571.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            20599..21294
                     /locus_tag="VXE01_000605"
     CDS             20599..21294
                     /locus_tag="VXE01_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749572.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            21311..22078
                     /locus_tag="VXE01_000606"
     CDS             21311..22078
                     /locus_tag="VXE01_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749573.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(22431..23630)
                     /locus_tag="VXE01_000607"
     CDS             complement(22431..23630)
                     /locus_tag="VXE01_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0749574.1"
                     /translation="MRNMWVVIKETYLRHVKSWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(23627..24520)
                     /locus_tag="VXE01_000608"
     CDS             complement(23627..24520)
                     /locus_tag="VXE01_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749575.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            24637..24717
                     /locus_tag="VXE01_000609"
                     /pseudo
     CDS             24637..24717
                     /locus_tag="VXE01_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            25202..25415
                     /locus_tag="VXE01_000610"
                     /pseudo
     CDS             25202..25415
                     /locus_tag="VXE01_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            25830..26447
                     /locus_tag="VXE01_000611"
     CDS             25830..26447
                     /locus_tag="VXE01_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV0749576.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(26490..27377)
                     /locus_tag="VXE01_000612"
     CDS             complement(26490..27377)
                     /locus_tag="VXE01_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0749577.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIEFNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(27526..29409)
                     /locus_tag="VXE01_000613"
     CDS             complement(27526..29409)
                     /locus_tag="VXE01_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0749578.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSIPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            29786..31240
                     /locus_tag="VXE01_000614"
     CDS             29786..31240
                     /locus_tag="VXE01_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0749579.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRFQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            31221..32186
                     /locus_tag="VXE01_000615"
     CDS             31221..32186
                     /locus_tag="VXE01_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0749580.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(32221..33495)
                     /locus_tag="VXE01_000616"
     CDS             complement(32221..33495)
                     /locus_tag="VXE01_000616"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV0749581.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQIANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(33495..34667)
                     /locus_tag="VXE01_000617"
     CDS             complement(33495..34667)
                     /locus_tag="VXE01_000617"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV0749582.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(34798..35046)
                     /locus_tag="VXE01_000618"
     CDS             complement(34798..35046)
                     /locus_tag="VXE01_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749583.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(35114..35740)
                     /locus_tag="VXE01_000619"
                     /pseudo
     CDS             complement(35114..35740)
                     /locus_tag="VXE01_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(35802..36251)
                     /locus_tag="VXE01_000620"
     CDS             complement(35802..36251)
                     /locus_tag="VXE01_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0749584.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(36253..37011)
                     /locus_tag="VXE01_000621"
     CDS             complement(36253..37011)
                     /locus_tag="VXE01_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0749585.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(37126..39105)
                     /gene="pknB"
                     /locus_tag="VXE01_000622"
     CDS             complement(37126..39105)
                     /gene="pknB"
                     /locus_tag="VXE01_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV0749586.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(39102..39842)
                     /locus_tag="VXE01_000623"
     CDS             complement(39102..39842)
                     /locus_tag="VXE01_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV0749587.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANSAGGLDNITVALVSMNEEDEE"
     gene            complement(39857..41170)
                     /gene="rsmB"
                     /locus_tag="VXE01_000624"
     CDS             complement(39857..41170)
                     /gene="rsmB"
                     /locus_tag="VXE01_000624"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV0749588.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVTKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(41163..42098)
                     /locus_tag="VXE01_000625"
     CDS             complement(41163..42098)
                     /locus_tag="VXE01_000625"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV0749589.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMIFRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEDQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(42111..44507)
                     /locus_tag="VXE01_000626"
     CDS             complement(42111..44507)
                     /locus_tag="VXE01_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV0749590.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFDSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRSGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(44573..44887)
                     /locus_tag="VXE01_000627"
     CDS             complement(44573..44887)
                     /locus_tag="VXE01_000627"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV0749591.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(44912..45538)
                     /gene="gmk"
                     /locus_tag="VXE01_000628"
     CDS             complement(44912..45538)
                     /gene="gmk"
                     /locus_tag="VXE01_000628"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV0749592.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(45668..47281)
                     /locus_tag="VXE01_000629"
     CDS             complement(45668..47281)
                     /locus_tag="VXE01_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV0749593.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILVQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(47624..>47999)
                     /locus_tag="VXE01_000630"
     CDS             complement(47624..>47999)
                     /locus_tag="VXE01_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEV0749594.1"
                     /translation="DFPQIQNKIYHYLIKRINDKRVEGVKTFPDPREKSVSDLYNLSR
                     KGYFSDFEILKDIEEDIRGLYPEVDWTWFHDRSDDVIHRLLEHRTPNNIKTYFSKNEE
                     DNKLINEYILKAFDEDKLILKK"
BASE COUNT        13837 a        10790 c         9065 g        14307 t
ORIGIN      
        1 taataatgtc cttgaaagta gtttcagctg aacatttata atccataaaa agaaaacaga
       61 aactcatctg tttttatact caatgaaaat caaagagcaa actaagaagc tagccgcatg
      121 atgctcaaaa cactgttttg aggttgtaga taagactgac aaagtcagct caaaacaccg
      181 ttttgaggtg gcagatagaa ctgacgaagt cagtaacata tatacggcaa ggcgaagctg
      241 acgtggtttg aagagacttt tgaaaagtat taacacttac agacaagcct gacgatagca
      301 agaactaccc tactcgatag gtatcggctt ttgctttctg aaaaaaatta ttttaagcaa
      361 tttgacaaat ctagcaacaa aaaattctat aaatataata gattgaaact agaatagtac
      421 acctttgttt ctaaaacatt gttagaaatc gatttgactg tcctgatcaa tttgtcctgt
      481 tcttgtttca ttttactata tttctatgat aaaacgcata gtatcaagtt ttcttaatcc
      541 cctgatacta tgcgtgtttg taatttttaa gattttgtac ttagagtcga ctccttattt
      601 tagatattta aaaggaatct cacttccaca gagccagttg tagacttggt cattgacaaa
      661 tacattcatg gcttcgtgag catactcagg catgatacga taggttttat cgcaggtcag
      721 acgattataa atcgcaaact gggtaatggg atagcaaaca tcgtcgtcca agcccgtaat
      781 catcttaacc tcaccttgga tacgatgggc aagatttttg acatcgatat aggcaagggt
      841 cgccatgatt tcctcctctg tttcatggaa ggggtcgtga aacttgaaat aacggaaaag
      901 ttcgtcgtaa gcctcgctag tattaccaat ctcaatcacc cgtctgaagt ctgacaagaa
      961 gggataaatg gcaactgttt tctgaattcg aggattgagg gctgctgcaa ctagggctag
     1021 agcccctcct tgtgaggcac catagctaga aagacgcttc tcatcaacct gagacagact
     1081 agcaacaatt tcgaccaact ggtaaatatc cagataaaca tccttataaa agaggtggtc
     1141 ccgaccttcc acagcaccac ggataatatg ccccttcacg gtatttccta aaggagaacg
     1201 caagccgtct tgtgagtaac ctgactggcc ccgcacatcc atggaaacaa caccgtaacc
     1261 agctacggtg aagcccagca tgtcggccca gtcccagcca cgtcccatat aaccatgaaa
     1321 atggaagatt agtggaacct tctcctcact ctttggaaga acaatgcgtg catagacctt
     1381 tccttccttg cttccttcaa atgttaactc atagcacttg acttgaggaa tgtggaaatc
     1441 tctttcctcc aagtggtagg atggaagcgt ggaaacattt ttcacttccc catcccagaa
     1501 agcatcaaag tcttccggaa cctcatccct tcctctatag gtcttaattt cttctagcaa
     1561 agctggattt ttcatagcat gctcctttta ttttgtaatc gttaccacaa ctgtagcata
     1621 tctatgtaat caatgcaaga aagaagggta aatagaaagt gaatttagat tctttacttt
     1681 taggatgatg ggctgaaagt agttttagaa acgaaaaaag agcatttcgc tctctcttct
     1741 gtttatacta gttttttgct tccttctttt ggaaagtggt ttggtaattt actttaatcg
     1801 ttactgtcat atgagagtcc tcgtttcttt ttgatgactt tagtataaga gccaaaccta
     1861 aaaactagct taatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgta
     1921 tatatatgtt actgacttcg tcagttctat ctgccacctc aaaacggtgt tttgagctga
     1981 cttcgtcagt ttcatccaca acctcaaaac agtgttttga gcaacctgcg gttagcttcc
     2041 tagtttgctc tttgattttc attgagtata agttttcctt agagaaagct taatccagat
     2101 gttctttctt ttccagatga agggcaatca tgcgccactc tggatcttct tgccaagctt
     2161 ctatagaact aatgtagcta gcaacctttc ttgcttcttc taaaatcgga aaatcttcga
     2221 taatatcagc cacttggaac tctggaagtc ctgactgtct ggttccaaaa atctcaccag
     2281 aaccacgcat tttcaaatct tcctccgcaa ggacaaatcc attggtcgtt tctgtcatga
     2341 tgcgcatgcg gtctttccca gaatccgtct tgggattggc aacgagaaca gcgtaggact
     2401 gcttgtcccc ccgaccgaca cgacctctaa gctggtgaag ctggctgaga ccgaagcgat
     2461 cggcatccat gataatcatg acagtcgcat tgggaacgtt gaccccaacc tcaataaccg
     2521 tcgtcgaaac cagaatatcc gtctttctct ccttgaaatc ctgcatgatc tggtcttttt
     2581 cgtcactctt catcctacca tgtagaagag ccacctctgc cttgcctgca aaatgagtcg
     2641 tcaactcctc tgataaggca atggcatttt tcaaatctag agcttctgat tcttcaatca
     2701 aaggagagat gacataggct tgggaacctt tttgaatttc cccctctaac caagtcaaga
     2761 cctgaggtag ttgctcatgt ttgatccagc gcgtcacaat aggcttccga cctgctggca
     2821 tctggtcgat aatggaaaca tccatatctc caaaggctgt gatggcaagc gtccgtggaa
     2881 tgggagtcgc cgtcatcatg aggacatctg gattgtcacc tttttcccgt aaaatacgcc
     2941 tttgccctac accaaaacgg tgctgctcat cgataataat caaaccaaga cgagcatact
     3001 ccaccccatc ttgtatcaga gcgtgagttc cgataatcaa atcagcctca cccttggcaa
     3061 tggtctccaa gacttctctc ttttctgcag ctttcaagga acctgtcaag agagccagtt
     3121 tcaaattggg aaaaaggttc tgtaaactct caaagtgttg ctctgcgagg atttctgttg
     3181 gtaccattag ggcagcctga taacctgctg tcactgccgc aaacatggcc aagccagcga
     3241 ctaccgtttt tccactcccc acatcccctt gtaggagacg attcatgtgg tggtcggact
     3301 tcatatcagt taaaatttcc tgcaaactct tttcctgagc ttgggtcagg gcaaaaggaa
     3361 gacttacttt aactgctgtc actttttcct gagaccaatt cagaaccaga ccacttccct
     3421 gaactctatt ttcagacttg agcgtctgca actgcatttg gaaataaaag agttcctcaa
     3481 acttgatacg gcgaagagcc tgcttgtatt ctgccaaatc ctttggaaaa tgcatagctc
     3541 ggactgcctg acaacgggac atgagtttgt atttgtctag taaagactgg ggcagatttt
     3601 cttctatcaa gaggtccagt ccctgatcaa aagccgtctt gatgacctta accagactgg
     3661 cctgactgat tccctgagcc agacgataga caggctggag gtcatcttct acctgagcca
     3721 gaaccttcat cccagtcaga ctagccttag cgcggtccca ttttccaaag acagcaaggg
     3781 ttgctcccaa ctctatttta tcagccagat agggctggtt aaagaaattc accgcaaaaa
     3841 cgacctctcc ctgcttgaga ctaaaacgca ggcgattgcg cttgaaacca taatactgga
     3901 cactagcagg agtcactacc tgaccagaaa gaactgcctt ctcaccgtct tccagctcca
     3961 gcacctgctt ggttttgaag tcttcataac ggaaaggaaa gtagagcaag agatcttgca
     4021 agttttcaat tcctagtttg gcgtattttt ctgctgactt tggtcccaca ccaggcaaga
     4081 catgcaaggg ttgatgtaga ttcatgctcc actcctttct tttctaataa tattctctcg
     4141 gaatacggtc gctgaggagg caaaccacct catagttaat ggttacgcgg taggtcgcta
     4201 cctgagttgc agtgatttcc ttatccccat tggagccaat caaggttacc ttggttccga
     4261 gtgggtaagg cttaggcaat cgaatagtga tttggtccat cgaaaccctg ccgacaattg
     4321 ggcaagcttg gccatctacc aagacagaga aattttgcat gtctcttgtc catccatctg
     4381 catacccgat tggcacggtc gcgatgactt gctcgctatc cgcttgataa gttgctccat
     4441 agcccatgca agctccagct ggaactgtct tgacatgaac cagagcagac tccaaggtca
     4501 aggccggtat caaatcataa ggcaaatcca agaccgctcc acttggattg aggccataca
     4561 tggcatctcc catacgaacc gcattgaaaa tagtctctac atgccaaaga gtcgttgcag
     4621 aattgctagc atgaaccagc tctggaactt ccttcatact agctaaaata gttttaaacc
     4681 gttctaactg ggcattaaaa tagtcatctg attcctcatc agcagtagca aagtgggtaa
     4741 agattccttc aacacgaaca ccgtgttgtt ggagcaaatc ttgagcctgc tcaacctcac
     4801 tggcctctct aaaaccaatc cgtcccatcc ctgaatcaat cttgaggtgg actgtcaatc
     4861 cagttaggtc cacttcctta tctaagagtg cttgaatcca ctccagtcca gccactgtca
     4921 aggtgaagtc atattcttta gctagagcaa cagcttcgat ttcagaaact cctaaaatga
     4981 ggattggctt gctgagtcca gcttgtctga gttcaatggc ttcatcgata ttggaaacgc
     5041 aaaagccatc aacatcatct tgaattgcct tggcaacggc aacagctcca tggccataag
     5101 cattggcctt gaccacagcc cacttgagcg ttccttgagg gatatgagcc cccatttgct
     5161 gaatattttg tcgaatagct cccagatgaa tcagaacctt ggttggtcta tgtggactag
     5221 ctttcatgat tttcctccaa aatgacactg gctgtcacaa actgatcggt gtggctgata
     5281 gacagccaaa tctttcctga aaatggtgcc tgactaaaat aaggcgcccc acgttcattg
     5341 ttcaagactt ccaaatcctg aaaaccgagc ttgctaatgc ccgttcccat agccttggaa
     5401 aaggcctcct tagccgacca gcgaccagct aaatattcta tttgcctgcg tcctttgaga
     5461 ctggtgaagc gctccatttc ctgagcggtc agtacacgct tagcaaatcc ttcatgtcgt
     5521 gtaactgcgc tttctatcga agccaattct tcgatgtcaa ttccgtgtcc aactatcatt
     5581 ctcatcaaaa ggagttgaga ttccccaact ccatcctttt cacttatttt gtcaaggtaa
     5641 cataaatctc ttctaccaag gcctctgtat tttcccaacc taggcaaggg tcagtaatag
     5701 agcaaccaaa gacctctggt tggttttgac gaccatctgc taggtaagat tcaatcataa
     5761 atcctcgaac cgtcttttta attttctcat tccaatcacg attctgcaag gtctggcgaa
     5821 caattcgaat ctgctccata tattgcttgc ctgagttatc atggttggtg tcaatgagga
     5881 taaaaggatt ttcaagtccc atggtttcat agcgttcaat ggcttggagt aggttttcat
     5941 agtagtaatt cggcatataa ttgccatact cgttgactgc tccacggagg ataacatggg
     6001 ccaaaggatt acctgatgtc tcaacttcct gcccatgata aaggaaggtt tgcttgtttt
     6061 gagcagcata gatggcgtta aacataacac ccaaatttcc tgaggttgga tttttcatcc
     6121 ctactggtgc atcaatccca gaagccacaa agcggtgctc ttggtcttcc acagaacgag
     6181 ctccaacggc atggtagctg accaagtcat ccaccaagat cagatttgac ggataaagca
     6241 tctcatctgc cgttgtcaaa ccagtctctg taatcacgcg gtagtgcaac tggcgcacag
     6301 cctgcaagcc attaatcagg cttggagcct tagaagtatc tggctggtga actaatcctt
     6361 tatagccgtc tccattggta cgaggcttag cagtatacac gcgcatgacc atgaaaatct
     6421 tatccgctac cttcttttgc aaggcggata aacggcgagc atattccaag accgcctctt
     6481 cattatcaga agagcaagga ccaatcacca agagaatacg gtcatcttcc cctgaaataa
     6541 tatctgccaa ttccctgtca cggctttcct tgagtctcaa ggcttccgca gacaattggg
     6601 tttcagcctt gatgacttcc atatcgattt cttgaccttt ttcaataaat gccatcttat
     6661 tctcctaacg ttttgtaaat ttctctgaca agagcttctg tgttatccca acccaggcaa
     6721 gggtctgtga tagacttacc aaatacttct ggctcatttt gtcgaccatc ttccagataa
     6781 gactcaatca taaaaccacg aacgaactgc ttaatttttt cattccaagc acggttaatc
     6841 aaggtctggc ggacaattcg gatctgttca atatactgct taccagaatt gtcatgattg
     6901 gtatcaatga tgataaaagg attttccaag cccattttct catactgggc aatggtatca
     6961 attaaattgt cataatagta gttgggaata ttttttccat actcattaag agcaccacga
     7021 agaatagcgt gtgaaagcgg gttcccagtt gtttctactt cttttcctaa gaaaaggaaa
     7081 ctttgtttgt tttgagcagc ataaatccca ttaaacatga cattgagatt tccagaggtt
     7141 ggatttttaa aaccagtaga aaatcctgcc ccacttgcca caaagcggtg ttgctggtct
     7201 tcaactgaac gggcaccaac tgccatgtaa gaaatcaaat catctacaag cggaaggttt
     7261 tcaggataaa gcatttcatc agcagttgtc atccctgttt ctgtgatgac acgatagtga
     7321 agatggcgaa cggctttgat tccattgata agactaggcg cttctgtcgc gttaggctgg
     7381 tgaatcaagc ccttatagcc atctccgttg gtacggggtt tggcagtata aacacgcata
     7441 accataaaga tacgatctgc cacttcttct tgtaggactg ccaaacgctt agcgtattca
     7501 aggacagctt cttcgttgtc agatgagcat ggcccgatta ccaagagaat tcgctggtct
     7561 tctccacgta taatggcttc tagctcttga tctcgctgtg atttcctctc caaagcctga
     7621 ccttctaatt ttgacaaggc acgaacttct tctatattta ttttagagct ttttgctgta
     7681 aataccataa ctcatctcct tataaagcaa acggataccc agtaaaaatt tacttttcac
     7741 aagatatccg cctctaaact atctcatttt attgtctttt accgtgacag tttttaaatt
     7801 tcttaccaga accacatggg caaagttcat tgcgtccaat ctggctcaaa tccaaatctt
     7861 ctggcatact tgcttggtga gcagcgatat tgcgagtcgc tgttgtactg atatgacgtt
     7921 ctgcctgtgg tctttcttgt tcatgaattt gtgctttcat catcaagcgt gtcacatcaa
     7981 actcaatcga accaatcata tcattaaaca tacggaaacc ttctgcctga tactcaacaa
     8041 cagggttgtt ctgagcatag ccacgaagtc caaccgcgtt acgcaattga tcaagggcat
     8101 cgatatgatc tgtccacttg ttatccacca ctcgtagaat caaaactttt tggaattctt
     8161 taactgcttc ttcatcgcgt agttttgaaa cctgactatc gtaaaccttc aaggcacgtt
     8221 ggaaaagctc ttccttgatg gccttatcag acaagcctga caagtcttcc atcgtaatag
     8281 aatcttcagg aagcaagttg tacttagcga agttcaaaat tgcctctagt ttctcatctt
     8341 gtttagcacg cgcatgaccg tcaacgacac gaccaatcgt gcgtttgatc attgcctgaa
     8401 tttcaggtgc caagtcacgg tctgcagtaa tgacatcata acgttgagta tagataatct
     8461 cacgttgttc acgcatgaca tcgtcgtatt gaaggacttg tttacgggta tcgtagttat
     8521 ttccttcgac acgtttttgc gctgcttcaa cctgacgcgt caacatgcga gactcaatcg
     8581 cctcttcaga catgttgaga cgttcaaaga ttcccttcaa gcgttcagaa ccaaaacgtt
     8641 tcatcaaatc atcttcaaga gataggtaga attgtgactc acctggatct ccttgacgac
     8701 ctgaacgtcc acgaagctgg ttatcgatac gacgactttc atgacgttct gtaccaataa
     8761 cacaaagtcc tccaagttca cgaacacctt caccaagctt gatgtcggta ccacgacccg
     8821 ccatgttggt tgcgatggta acggcaccac gttgaccagc attcatgatg atttgggctt
     8881 ctctatagtg gtttttggca ttcaagactt cgtgaggaac accagctgca accaatttct
     8941 tagaaatgta gtcactagtt tcaaccgcta ctgtaccaac caagacaggt tgaccctttt
     9001 ggtaacgagc cttaacgtct tcgacaaccg ctttaaactt agattcgata cttgcataaa
     9061 gaaggtctga gtggtcaata cgttgaacag gacggtttgt tgggattgga ataacacgaa
     9121 tgttgtagat ttcacgaaat tcttcttcct cagtcttacc tgtacccgtc ataccagaca
     9181 attttttgta catacggaaa aggttttggt acgtgattga ggcagatgtc ttggtttcat
     9241 cctggattgg cacaccttct ttggcttcaa tagcttggtg caatccatca gaataacgac
     9301 gaccttccat ggtacgacct gtaaattggt cgacaatcaa gatttcttgc tcttcgctca
     9361 ccacatagtc aatatcgaga agcatgatgt agttggcacg aagggcgtta tcgataaagt
     9421 gggtcaaagc cacgttttcg atgtcataga ggttttcaag tttgaagtag ctttcagccc
     9481 tgtcaatccc tgaatcagac aaaccaatag tcttagactg cacatcgatg atgtagtcat
     9541 ctttgttcaa agattttaca tagtggtctg ccatgtgata caactgactg gtttcaaccg
     9601 cattggcacc tgatacaatc aaaggtgtac gagcctcgtc aatcaagata gagtcaacct
     9661 catcgaccaa ggcatagtta agcggacgtt gtaccatgtt ttcagcgcga acgaccatgt
     9721 tgtcacgaag gtagtcaaat ccgatttctg agttagttga gtaagtaata tcacactcat
     9781 aggcttcttt tttctccatt ggagatttgg tagccaagtt aatccctact gacaaaccaa
     9841 gccaagagta caattcaccc atctcagtcg cgtcacgttc tgacaggtat tcattaaccg
     9901 taactacgtg aaccccttta cctgaaaggg cattgaggta taccggcatg gtcgcagtca
     9961 aggttttccc ttcccctgta cgcatctctg gcacgtcacc atggtgaaga acaatccccc
    10021 ccatgacctg aaccttataa gggaagagac ctaggacacg tttggcacct tcacggacaa
    10081 ccgcaaatgc ttcgtaaagc aatgaatcca gtgattctcc attttgataa cgttccttaa
    10141 attcaactgt ttttgctttt agttggtcgt cagtcaaagc agccatttgg tcttcgtatt
    10201 tgaaaacctt gtcagccatc ttttccagac gacggatttc tcctttatca ttttcgataa
    10261 ttgtttttaa aatattagcc atgtttttcc ttactttaaa ttccgaatat tttagaatgt
    10321 tcctttaatt ttagcacaat tactgattat tttcaaggaa gaatccccat tttgaagagg
    10381 aaaaagaggt tagttttcaa gctaacctct ccgactttta tgactgttta attgccaaaa
    10441 atcggcaaaa tggcaaatgt gataaataag ttaatccaaa gagaaagaca gcaaatcagt
    10501 tcaaaaacaa agagactgac tttcttggac agcaaggcca tgagaatgga cagaattcca
    10561 aaagctagca agattttctg tatgatgaag atgtcaatcc ttatccccag aagtggttta
    10621 tcccaaggga taaagaagaa agacagccag atcagcagaa ctaaaccaat ataaaccttg
    10681 gaatagcgtg taataaatga ttttagatgt gccataagcc atctcctagg attgtatatc
    10741 ctttacattt gtatatgtcc attttcgaca actaatacat ctgtacaaag gtctgaaata
    10801 tcttccgata tgtgcgacgt caggataacc agaccatttt cttttttcag gtaagataaa
    10861 atgacctgtt tggttaacct cacactcttc tcatccaaag cattcatagg ttcatcgaga
    10921 aagagtatag aaggagagga aataaaggct tgaatcaagg ccattttttg ctttgttccc
    10981 aaggataaat gccggtattc aacgtcttca aattcctgta aatcatagta ttgaatccaa
    11041 taggcaattc ttttttccgt aactttagat gaaaaatacc ttaacagttc caaattttct
    11101 ctcagggata aatgagataa aaactcgact ttttcaatta aaattcctgc atcctgaata
    11161 taatgatttt ttatcccgta aactttacca tcttgaagaa cttttccttt gtcaagctta
    11221 atataaccag caagtacctt taaaagaacc gtcttgccag atccattatc acctttaagt
    11281 ccataaattt ttcctgattg aaacaccaaa ttcaactgat ttaaaatagg tcttttccca
    11341 taaattttct gtccatttat aatttcaagt ttcatcgttt atcctttctt aaatttctct
    11401 tccaagcgac taacaatcaa cataactaat aagcttaaga gtagtaaata cactgttaca
    11461 atatgatcca tcatccattc ttgtcccaca aatgctaaaa aatagagaaa aaaggaaaaa
    11521 ccagcgcccg cactaatcag tgctatcaga taagacagta gtaagtacaa catcattaac
    11581 tgagcaagta aaaagaaaag tgcgactgtt ttgaaatgaa ttcctagcgg aagtaaacca
    11641 aggaaccaga caagtaaatc ttgagtaaaa aatttagaaa tgacaaccaa tcgtttcctt
    11701 gtataatcga aaaaggagct tgattgatag cgaatcaagt gatggtaatg gtctgccaaa
    11761 tcactttcaa gtaaaatgac agagagccat cctaccatga aaagcgaaag gtttaacaag
    11821 agtttgggga tttctaaatt cgcttcagaa tagtcattat aggaaaaaat tgaaatcaat
    11881 tctctcttga aaaagataac agcatcctgc ttttgaaccg ctgttgacaa tagatagttt
    11941 atcaaaatca tcatcagaac tatacgaagt agtaaaacaa tctttctctt tagcaaaata
    12001 ttgttaaaat tcttaaacat tatcttcata tttttcaagc accatataag ggacaatata
    12061 aaggatataa ggagtaaaga gtttcatcaa acttacatcc ccatagctag cttgcatcaa
    12121 actcgtcata ggaaccatat agtaaggcaa ggcactatag agcagcatag aaccaagcca
    12181 aagaaacatc aaataggtga ttgccgaacg agtcacattc cccacataat caactatttg
    12241 taaaaaatag attgcattga tgaaaatacc gattagtagg acacaagtaa agaacaaata
    12301 gctttttatc tctccatcta ggagtctttg taaaccactt ccatcagaaa atagagaatt
    12361 ccatccaaga ggagaaaaag tcccaaggaa ataggttata attgcaatta tcagcacagt
    12421 cactaaatat atcaaacaag ggatacttgc aacttgcaaa gtcaactttc tttttaaccc
    12481 ttgatagctc acttctcttc caatactcaa tcgtaaaact ttatttttca gctcaatata
    12541 ttgaaaacct agcaaaacaa tgatgattgg aataataaat gattgataaa aacctagatt
    12601 gaactggaga atacgaaaat ctaatgctga ttttaataag tcatttttaa ttgcttgtcc
    12661 atcgaattta gctagatcgg gcgcatgaat atcaaaaaag aaataagtca tcaaaacatc
    12721 acgataaacc aaagcaagaa aaagcaaagt aagcaagaca taaacaaatt tatgccttgc
    12781 aaaagttaag agaggaatct tcataaatta tacctacttt acgaattaat ttggtgacca
    12841 actacctgaa atggcagctg ataaatccca ccaattttgt cttgccatat ctgctgcata
    12901 aacatagcca accgttgccc aattaccatg agttgaacga gtaccacagg ttgttaacga
    12961 ttctccacta cgagcttctc cattagaatt tactatacga tgcttaacag tcatgggatg
    13021 taaatttcta caaggattta agttcatgat atattccgca ccttcatttt ctttagtcaa
    13081 ataacctgtt ctcttataac tggtagtaat aacaaaatta ctaaaagcac ctatctgatt
    13141 tgcttctacg aaagtagttc caacagcact tatcattaaa acaggaataa ccattttcaa
    13201 taatttctta gttttcattt tttattcaag aagattcctt ataacttcta ttttaaatat
    13261 agacttattc taaacgatgg tatatcatac aaattcctcc tttacttatt atgtatagac
    13321 tctaatttct ttatccccaa aaccatgttt caaaccagat aagttgaatc caactccaaa
    13381 tcaaaaatcc agagtttttc ggtaaattct tcaaatattt tttaaagccc atgacttttt
    13441 ccctcctttt tgatataata ataccacctt tttctacgtt ttttataaat gtagaaaata
    13501 ttcacattta cctaggagga acaatatgag atgggattat gaacagattt ttaaagaaat
    13561 tcgaaagtca aaaggattga cccaacaaga tgtatgtgga caagtcatac atcggacaac
    13621 tctaacaaat attgaacacg gtaaagttat tcccagtttt gaaaacatgg tatttcttct
    13681 tgaacaaatt gatatgagct tggcagaatt caagtatata tgcaacgaat accatcctag
    13741 taaaaggcga gatattattg tagagagcca aaatccgtct acttttcaag atactagaaa
    13801 aatggttgaa ctcactgaga aatgtcaaaa atatcttaag acacatcacg atgttcctat
    13861 tcaaaatatc tatcgtcata caaaaattgt cacagagtta cgaactaaag gattcaaaaa
    13921 caaccacgtc ttgaaagatt tgtctgaaga aatttgggac tatcttgaac ctatggatac
    13981 atggtacatt agtgatttga aattgcttgg aaccattctc tttttctttc cttctgaaaa
    14041 tcttcccctt cttattgata gaattatgaa aaccatcgag aaatataaat acttccgaga
    14101 aacaaaagta tttttatcat cttttttagc caatctctcc actgtatatt ttcaacatca
    14161 tttattcaaa gaatgtgaaa caatcaccct acaacttttg gtattagcag aagaattaaa
    14221 aatatacgat attcttggat tctctcaagt acgcttggga atactacaac ataactccga
    14281 tttgattgat aaaggaataa ctttattacg actaaccaaa gaagaggcat tagttaaaat
    14341 actcgaaaaa gaaattaatg atttttcaaa cctataattt gtaataactc tcatcatttt
    14401 attatagtag attgtaatag aatgtgaacg aatcaattag gggatctaaa gcattttata
    14461 ccaatgtttt ataagttgta ttgtattatt ccatattcaa tccactatac aagatgaata
    14521 tttctctcaa gtttcataat caaaataaaa atgactgtat ctatagctcc ataaacaaat
    14581 catagataca gtcatttttt agttcctaca ccttccttta tgcacacctt tagacttccc
    14641 tagttcccgt ctcaagtcaa gcattttttt gaaacagata tagtctaacc agtcactagc
    14701 aaaagcgata agtagtaata atagccaaat accccataac ttgatatctg tcaaatttct
    14761 caagacgata ttgaaaaaca gaactgaaaa aactgtccaa gcaaggctaa aaagagcata
    14821 gagggtgatg taaatccagt aaaaatagta aaaaattggg aaaaatttac tttctctatt
    14881 atccttgtca atccagctga aaaagtaaaa acagggtaat aagattatca ttttaaacaa
    14941 gtgttccatc acaagcctcc ttttttaaat tgttttcttt agtttcgttc tattaaatgt
    15001 tattaccaat ataaaccttg gaatagcgtg taataaatga ttttagaggt accataagcc
    15061 acctcctaca aatagaaacc gatataaatc aatgccttcc acccttagac ttccctagtt
    15121 cctgtctcaa gcgaaacatt tctttgaaac aggaataagt taaccaattc ataccaatag
    15181 ctagcagaat aaaaagaaac caaatgcccc ataacttgat atctgtcaca tttctcaaga
    15241 cggtattgaa aaacagaact gaaacaactg tccaagcaag gctaaaaaga gaatagaagg
    15301 ggatgtaaat ccagtaaaaa taataaaaaa ttggaaaaaa cttactattt ctgttggcct
    15361 tttcaatcca gttatcaaaa taaaagtacg gtgctaaaag taagaattta aacaaatgtt
    15421 ccatcaccga catccccctc cttcttttaa tagcgttttc tattatttta ttatatcaaa
    15481 agaatctgga aatgtcattc cagattctac ttttttattt acgctttctt gcgatgagat
    15541 gaatcggtgt tccctcaaag acaaaggcct tgcggatttg attttccaag aaacgtaggt
    15601 aagaaaagtg catgagttct tcttcgttga caaagataac aaaggttggt ggtttggttg
    15661 ccacttgggt cgcatagaaa atcttgagac gttttccttt gtctgtcggt gttgggttga
    15721 tggcaatggc atccatgatg acatcgttca agacagctga tggaatacgt gtattttgac
    15781 tttcgctgat ttgcttaatc atcccaggaa gtttgtggag acgttgcttg gttaaagctg
    15841 atacaaagat aatcggtgcg taaggcaggt attggaactg ctcacggata tcttcttccc
    15901 agtttttcat agtgtggtta tctttttcaa gcgtatccca cttgttgacc acgataatca
    15961 tccctttacc agcttcatga gcaaatccag cgatacgctt gtcgtattca cgaatcccct
    16021 cttccgcatt gatgaccatt aagaccacat ctgaacggtc aatagcacgc atggcacgca
    16081 tgacagagta cttctcagta ttttcataaa ccttaccaga cttacgcata ccagccgtat
    16141 caatcatggt aaactcttga ccatctgtat ctgtaaagtg ggtatcaata gcgtcacgag
    16201 ttgttccagc aacaggactg gcaataacac ggtcttcgcc caagatagca ttgatcaagc
    16261 ttgattttcc aacgtttgga cgaccaatca ggctaaactt aatgacatct ggattttctt
    16321 cctcatattc atttggaaga ttttctacga tagcatctag tacatcccct gtaccgattc
    16381 catggacaga tgagataggc agtggttcac ccaaaccgag agcatagaaa tcatagatat
    16441 catttctcat ctcagggttg tccaccttgt tgactgcgag gataactggt ttgtgggtct
    16501 tataaagctt acgagctacg tattcgtctg catcagtaat tccttcctta ccagacacga
    16561 caaaaacgat aacatctgct tcttccatgg caatttctgc ctggtgcttg atttgttcca
    16621 tgaaaggagc atctacatcg tcgattcctc ctgtatcaat catactaaaa gagcgattga
    16681 gccactcacc cgttgcatag atacggtcac gtgtcactcc ttcgacatct tctacaatgg
    16741 agattcgctc accagcgatc cgattaaata gggttgattt cccaacattg ggacgtccta
    16801 caatggcaat agttggtagg gccataattt ctcactttct acaataactt cttctgttta
    16861 agattttttc tagttgagct tggttctgct tggccaaact gttctgctag acgctgactc
    16921 cagcttgtgg tcgcacgcgc tccagcatag tcagcctgca cacggtcata agcttggatt
    16981 gcctcagttg actgttcttg gtattcttcc tcaaagacta cattatctag tggcagtctc
    17041 ggtttcacat catgagtttg atttggcaca cccagtgcca tcccaaagac agaataggtg
    17101 tagtcaggta ggttaaagag ctctgccact tcttcagact tgtatcgaac caaaccgata
    17161 atcacaccac catagcccaa gctttcagct gccaacaagg cattttgtcc agcaagagct
    17221 gcatcgaccg aactaatcaa gagaccttcc acaccttggg gttggaaggt gtcggtatga
    17281 agtcgggctc ccttttctgc tcggttcaaa tctccgacaa agagaaggaa aacagcagac
    17341 tggcgaatgg cttcttgagg taccaattca tacaaggcat ctttcttctc ttggcttcgt
    17401 accacaatca cagagtagga ttggaaattc ttccaagatg atgccatctg ggctgctgtc
    17461 aggatttcag tcaaatcttc ctgaggaagg acttgctcct taaatctgcg cactgaagta
    17521 tgagccttca tcaatttaat ggtttctgtc atcgacggtt tactccttct aaacgagtct
    17581 cctcagccaa ataacggatg cgttccatga cgcgtctggc ttcccaggtt tcgtcatttc
    17641 catttttccc tttagcgaaa tgcttctcca aatcttcaaa gttgaagtta gaggtgaaaa
    17701 aggtcggtaa attttcctgc atccgatatt ggagaatgac ctgcaggatt tcatcacgca
    17761 cccaagtggt ggattgctcg gcaccaatat catctaaaat caggacttca gaaagcttaa
    17821 tctcatccac taaggtctta acattgccat cactgatagc atttttgaca tcaatgacaa
    17881 agctaggata gtggaggaga gtggatgata caccacgttt ttctgataaa tcatgagcta
    17941 gggcagccac catgaaactt ttacccacac caaagtctcc atacaagtaa agacctttca
    18001 aattattggg gtaatcgtta acaaattcta tcattctttt tagaacagtt aagcgctgaa
    18061 catcatcacg ataaacatct aaaaaactga catttttcag gctagatgga aaattaatta
    18121 agttgagacg tttcttgata gccgcttctt tttcagctgc gattagttca ggagtttctt
    18181 cataagaaac atccgcatag ccatggttca tgactaatat aggcttgtag cctttggcaa
    18241 tataatctgt atctcctcgg aggaatttat ctctctcagt gatgtattgg ttaaacttgg
    18301 aaatactacg gttcaactcg tcctgattga gggattcttg ctggacaaag gccgcaacat
    18361 caggatcctt catgattttc tgaactaaat cttgatagtg aaaacgactt ggttgacgtt
    18421 tgagtacatc tccgacactt tccatctaat cacctccgtt atctaatttt gctaataatt
    18481 ctagggtttg gcgttccatc tcttctaatt cctcagcgga tgacgtattt ttatattcag
    18541 gattactcca tttaggaata ttggtttttg ctggggcagt ctgattctgt ttttgtgttt
    18601 ttgctttctg tcctcgctca cggatgcgca agactgcctc ttctgccgaa tgaatctttt
    18661 gataggcata gtcattggct accttcatgg catatttctc attgatattt gccgaatcga
    18721 ccttattaaa ggtcaataaa agaatgatat tgatgacttc gtccagcaaa cccaagccag
    18781 ccatctgttg caagagttct ctttctgttt gggtaatggt tcccttgcgt gtttgcttga
    18841 tttctgccaa gaactgcagg gcagttttac ttttggcttc tttgataatg atcgcttcct
    18901 taagactaaa gtcagaggaa actggttttt gagcaatttt ttcacgcatg cgtttggttg
    18961 aaataacctg agaaacagct gttgacttgg ccaattgata ggtttcaaac caagtccatt
    19021 tcttctcctc ggcaatggca aagaggttta agacatcgga ctgctcatcc gcaaagcgaa
    19081 gtccatctcg agccataagc tgacgaaaat ggtccaagtc aaaatcgttg gccactttct
    19141 tcttgagacc aaggtattct tgactgccta gttctgccaa ttctggaaag acttgattga
    19201 gtgagacagg tatttcttca ccatcagcac tttcaacttt caaatcctcc acagctacat
    19261 cgccaatctt tttctctaag agtctgcgat aaacaggatg ccccaagaag tcttgactag
    19321 atagaggagc atggagggct agctgataaa catccccctt ttgatagaga gtcaagagat
    19381 taaaagcaga taagattttc aatgatttta tcagtctatc catcccaaag ttgagatgat
    19441 tgaggatact tgaaaaaaga tattcctttc taccattatc ccaaaaacta atcgtataaa
    19501 gataaaggct cagtgcctcc tgaccgataa tcgggaggta gcactgtacc agagatgagg
    19561 tatcttgcga cacccgatta ttctttagat aagaaaaacg gtcaattggc ttcatttatc
    19621 tttccttttt ctttttagag gactgggtga tttgttggag caagctctct aactcactga
    19681 catccttaaa actacgatag acactagcaa aacgtacata ggtaatctcg tccaattcag
    19741 ccaactcctc catgacgagt gaaccaatgt cctcactttg aatttcattt tcatttcgac
    19801 cacggagttt ctgttcgata cgattgacta ccatgttgat ttcatcactt gacacaggac
    19861 gtttctgggc tgagcggata atcccattaa agattttatc tctggagaat tgttcccgtg
    19921 tgccatcttt tttaacaacc actaaggttc tttcttctac tcgttcgtag gttgtaaaac
    19981 ggtgttggca ctcgtcgcac tctcgtcttc tacgaatggt gttcccttct tctgcttggc
    20041 gactatcgat aacacttgac ttggtagccc cacattttgg acaacgcatc ctttccctcc
    20101 ttatcgtttt cttttcatta taccattttt taagcgattc ccaaaacaat tcttcttttt
    20161 gcttgacaag ttttttgttt tgttgtatta tttaattaag acaacaaggt aaaagaaagg
    20221 agactaagat gtcctggaca tttgacaaca aaaaacccat ctatttacag attatggaga
    20281 aaatcaagct tcagattgtt tcccatacac tggaacccaa tcaacaactt ccaaccgtga
    20341 gggagctagc tagcgaggct ggtgtcaatc ccaataccat ccaaagagcc ttatcagacc
    20401 ttgaacgaga aggatttgtc tacagcaagc gaacaactgg acgatttgtg actaaggata
    20461 aggagctaat cgcccagtca cgcaaacaat tatcagaaga agaattggaa cacttcgttt
    20521 cctccatgac ccattttggc tatgaaaaag aagaactacc aggcgtagtc agtgattata
    20581 ttaaaggagt ttaagcctat gtcattacta gcatttgaaa atgtatccaa atcatatgga
    20641 gcaacaccag cccttgaaaa tgtttctctt gacattccag ctggaaaaat tgtcggcctt
    20701 cttgggccaa acggctcagg aaaaacaacc ctgattaaac taattaatgg cctcttacaa
    20761 ccagatcaag gacgtgtcct catcaacgac atggacccaa gcccagcaac caaggccgtt
    20821 gtagcttatt tgcctgatac gacctatctc aatgagcaaa tgaaggtcaa agaagcccta
    20881 acctacttca agaccttcta taaagatttc aatcttgaac gcgcccatca tctacttgca
    20941 gacctgggca ttgatgaaaa tagtcgtctc aagaaactat caaaaggaaa caaagaaaag
    21001 gttcaactga ttttggttat gagccgtgat gctcgtctct atgttttgga tgaacccatt
    21061 ggtggggtgg atccagcagc ccgtgcttat atcctcaata ccattatcaa caactactca
    21121 ccaacttcta ccgttttgat ttctacccac ttgatttctg atatcgagcc aatcttggat
    21181 gaaattgtct tcctaaaaga cggaaaagtc gtccgtcaag gaaatgtaga tgatattcgc
    21241 tacgagtcag gtgaatccat tgaccaactc ttccgtcagg aatttaaggc ctaagcaaag
    21301 gagattattt atgttttgga atttagttca ctacgaattt aaaaatgtta acaagtggta
    21361 tttagccctc tacgcagccg tgctagtcct ttctgccctc atcggaatac agacacaagg
    21421 ctttaaaaat ctaccttacc aagaaagtca ggctactatg ctactttttc tagctacagt
    21481 ctttggtggc ttgatgctta cacttgcgat ttcaaccatt ttcttgatta ttaaacgctt
    21541 caaaggtagt gtctacgacc gacaaggcta tctgactttg accttgccag tttctgaaca
    21601 ccatatcatc acagccaaac taatcggtgc ctttatctgg tcattgatta gcaccgctgt
    21661 attggctcta agtgctgtta ttattctggc tttaacagct ccagaatgga ttcctctttc
    21721 ttatgtgatt acatttgtag aaacacatct ccctcagatc tttcttacag gtatatcctt
    21781 cctactaaat accatttcag gaatcctctg catctacctg gctatttcca ttggacagct
    21841 tttcaatgaa taccgtacag cactcgctgt tgcagcctac attggtatcc aaatcgtcat
    21901 tggatttatt gaacttttct tcaatcttag ttctaatttc tatgtcaatt cactggtagg
    21961 actcaatgac catttctata tgggagcagg tatagccatt gttaaagaac tcatattcat
    22021 agctatcttt tatctcggaa cctactacat cttgagaaat aaggttaatt tgctttaaat
    22081 aatttttacc tagatatgta acatactcat agaacaaaag agaccaggca aaaagttttt
    22141 aaaattagaa aacgcatagt atcaagtgtt aaaaatcctt gatattatgc gttttttgtg
    22201 agctgactta tttcctttca ctatatcgca aaatgaaata agaacggaac gatgggattt
    22261 tggaattcaa atcaatttat aagaatgttt tagaagtaat attatcctat tccagattca
    22321 gttcactata caattgagtt ttcaagcaac ctgtttacat aatgtgtaca taattaggtt
    22381 cgtgattcca cccttttcac ctttaaaaac ctcgctttcg caaggctctt ctatttataa
    22441 gataaggcac gtttaaaggt tttccaaatc cctaaatcat ccgtttgaag aacgagacta
    22501 gcatacatgc gtccgataaa tcctgttgct accaccgcaa aaatcactgt aatagcaagt
    22561 gaaatccatg cttctgctcc ccccgcatag ccattaatcg ttcgaaacgg cataaagaag
    22621 gtcgaaataa agggaatata agaaccaatc ttcaagagga gattgtcacc agctgcacct
    22681 agagctgtca ctccaaaaaa accacccata atcaaaatca tcaaaggcga caaggctttc
    22741 cctgagtcct caggacgaga aaccatagat cctaggaagg ctgccaagac tacatacatg
    22801 aaaagactga tcaaaataaa gagcaaggta ttcagtgaga tagcatctcc caagtgatcc
    22861 aaaataccag actgagccaa gaatggcaaa tctttaaaga gcaaaacggc agccagacca
    22921 cctacaacat agatcccaat atgcgttaaa atcactagaa acagagccat catccgcgca
    22981 tagaaatagt gacttgccct tatgctagaa aaaacgactt ccataatttt ggtgcctttt
    23041 tcactggcaa cttcctgagc tgttacaccc gcataggtaa tcagaatcat ataaagaaag
    23101 aatcctaagg cacctgctgc aattgtttga ataaactttt tattttcctt ggcttcatca
    23161 atcttttctg tgaattgaat tgtctgcgct aagcgttttt cctgctcttg agacaaggaa
    23221 gcagttgaac gattaagctg attttgcagt tcattgagtg tacctgtaac ctcaaattta
    23281 attccatttt caagcgatgt ttcgccatga taaactgcct ttagaacact atcttcttga
    23341 tcaatggtca aataaccttt taatttttct tctttaattg cttctttggc acttgcttcg
    23401 tctttatagt cgaagttaac accatttaca ttcttcagtc cttctgctac agatggcact
    23461 gttgtcacta ctgccacttt attattttta gccatagaag aaccttggat atgcccaatt
    23521 cctacagaga ttcctaaaaa gaggaacggc gaaatcacca taaagaagaa actccatgac
    23581 ttgacatgtc gaagataggt ttccttgatt acaacccaca tatttctcat acttccactc
    23641 ctgattctag tttaaagatt tcatcgatag ttggcgcttg ttggtcaaat gttgcgatat
    23701 attgaccttg agtcaagatt gggaagagtt cccttccagc gctctcatcc tccaaaatca
    23761 atttccaact gccttgtttg gtcaagctca cctgtttgac atgaggaaga ttttccaatt
    23821 cttccttgct tcgttcactt gaaacaaaga gacgcgtttt cccgtattga ttgcggacat
    23881 cctgaactgg tccgtgcaag accacacggc catctcggat catcagaata tcgtcacaaa
    23941 gttcctcaac attggtcatg acatggtcag aaaagataat ggttgctccg cgctcttttt
    24001 cctgaaaaat gacttgtttg agcaattctg tattaactgg gtccaatcca ctaaaaggct
    24061 catccaagat aatcaggtct ggttcatgaa tcagagtaat aatgagctga atcttctgct
    24121 gatttccttt tgacagactc ttgattttat ctgtcagctt tcctttcact tccaacctct
    24181 tcatccattg agggagtttt tctttgactt ctttggcatc catgcctttt agagtcgcca
    24241 agtagcgaac ttgttcaaga actgtcaatt taggcatgag actgcgttct tcaggcagat
    24301 aaccaatccg agcataggtc tcctgacgaa tatcctgacc atccagaccg atttctccct
    24361 gatattctag gaatttcaaa atactatgga aaatcgttgt ttttccagca ccattttttc
    24421 cgactagtcc caaaatacga cctggtcgcg cttgaaagtc aataccaaac aaaacttgct
    24481 tggatccaaa acttttctct agacttctta cttctagcat ctttcacctc cgaaatttct
    24541 tgcactcatt atactccttt ttgatagcct ttacaatgtt ttttgtccat ttttagaaga
    24601 ctattgctgt gtaaaatatg gcctggagca cttttatact caatgaaaag caaagagcaa
    24661 actaggaagc tagccgtagg ctgctcaaag tacagctttg aggttgcaga taaaactgac
    24721 gaagtcagct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaactat
    24781 atctacggca aggcgaagct gacgtggttt gaagagattt tcgaagagta ttagtgataa
    24841 atccattata cagtagcaaa cttaatttat accttccgct cctcaactgt ctatttttaa
    24901 tcctgaattg ttatttgagt aactcctttt tcctcataaa gttttcttcc tctaaaactt
    24961 ctggaaaaaa gcgaatagtt tcagacaaca tttttataag aaacaagttc atctgtcatt
    25021 tcaagaagga gtaatccttt atctactaat ggacggaacg gaattcaacc gcttgtccga
    25081 tatgttttct aaggattata tagtaaaatg aaataaaaac atgacaaata gatcgggaca
    25141 gtcaaatcga tttctaacaa tgttttagaa gtagatgcgt actattctag tttcaatcta
    25201 ttatatctat tatgcacacc actataggat ctaataaaaa tcacaacaag ttcattcata
    25261 gatggttacc tcagggaact aagaaaacga ctacaaagga agtcgcattc atcgaaaagt
    25321 ggattaacaa ctatcctaaa aaatgcttga actacaagtc ccccagagaa gacttctgga
    25381 tgactaactt gaacttgaaa tttagcaata attaattcac catctaacta tatttagtaa
    25441 ttatttcaga actgattaat attaaaatta actaacaatt caaaggattc atactagcca
    25501 taaattacgt ccatcagaga gagactctta ctacttttag attttagtct ttctagcttc
    25561 agaatacatc taaactttag ggaaaatgac tatttgaaag cgcgaatgcc tcaaaattat
    25621 ctcagataag ctattcgaaa cttagaatgc ttttaaattt atggaattgc gattattcga
    25681 aacctagaat gcatataacc tttagttgac agacctattc taagtctcga agggctattt
    25741 actttctatt ccttatcaaa aaagactcat tccccctttc tcctccaaaa tatggtatag
    25801 tagaaatata ctatctatga ggagtttaca tgtcacagga taaacaaatg aaagctgttt
    25861 ctccccttct gcagcgagtt atcaatatct catcgattgt cggtggggtt gggagtttga
    25921 ttttctgtat ttgggcttat caggctggga ttttacaatc caaggaaacc ctctctgcct
    25981 ttatccagca ggcaggcatc tggggtccac ctctctttat ctttttacag attttacaga
    26041 ctgtcgtccc tatcattcca ggggccttga cctcggtggc tggggtcttt atctacgggc
    26101 acatcatcgg gactatctac aactatatcg gcatcgtgat tggctgtgcc attatctttt
    26161 atctagtgcg cctatacgga gctgcctttg tccagtctgt cgtcagcaag cgcacctacg
    26221 acaagtacat cggctggcta gataagggca atcgttttga ccgcttcttt atttttatga
    26281 tgatttggcc cattagccca gctgactttc tctgtatgct ggctgccctg accaagatga
    26341 gtttcaagcg ctacatgacc atcatcattc tgaccaaacc ctttaccctc gtggtttata
    26401 cctacggtct gacctatatt attgactttt tctggcaaat gctttgacac gtaaaaaatc
    26461 cgtttggttt cccaagcgga ttttgtgctt tattttgaaa cttcttttgc aagaacaaag
    26521 ttcccaagtg tggcagaacc atttcctgcg actgctggcg tcacgatata gtcacgcaca
    26581 tctggtactg gtaggtaacc attaagaaga gatgtaaatt tctcacggac acggtccagc
    26641 atatgttgtt gagccatgac ccctccacca aagacaatca cgtctgggcg gaaagtcact
    26701 gtcgcattaa ccgcagcttg agcgatatag taggcttgaa catcccaaac agggttgttg
    26761 aattcaatag tttccccacg tacacctgta cgagcttcca aacttggacc agctgcataa
    26821 ccttctagac atcccttatg gaaaggacaa acacccttaa actctttttc aatatccatt
    26881 gggtgtctag caacataata atgacccatt tcagggtgac ccacaccacc gataaactca
    26941 ccacgttgga tgacgcctgc accgatacct gtaccgattg tgtagtaaac caagttttcg
    27001 atacgaccac cagcattgtt acgggcaacc atttcaccgt aagcagagct gtttacgtct
    27061 gttgtgaagt acattggcac gtttagggcg cgacgaaggg caccaagcaa gtccacattt
    27121 gcccagtttg gttttggagt cgtcgtgata aagccataag tttttgagtt tttgtcaata
    27181 tcaatcggcc caaatgaacc aactgcaaga ccagcaaggt tatcgaattt tgagaagaac
    27241 tcaatggttt tatcgattgt ttcgattgga gttgttgttg gaaattgtgt tttttctaca
    27301 acgttaaagt tttcatcacc gacagcacag acaaactttg taccgcccgc ttccaagctt
    27361 ccatataatt ttgtcatgat aaacctcttg tttttatttt ctttattata gcatacttcg
    27421 aaagtctaaa tgtctctatt ttttagattt tcctctgtaa atcttactat ctaataaaaa
    27481 cgaacaaaca tgtcatttgt tcgttttcac attagagagg attgattaga ttttcacttc
    27541 gatcacagca tcccccttcg caactgaacc tgttgcgact ggagctactg aagcgtagtc
    27601 agctgtattt gtaacgataa ccattgttgt atcatcaagt ccagctgcag cgattttgtt
    27661 tgagtcaaat gttccaagaa catcgccagc tttcacctta ttaccttgag caacttttgc
    27721 ttcaaaaccg tcaccgttca tagatacagt gtcaatacca acgtgaatca aaacttcagc
    27781 accatttctt gttttcaaac caaaagcgtg ccctgttgga aaggcaattg aaacttcagc
    27841 atcagctggt gcatagacca caccttggct tggtttcaca gcgatacctt gtcccatagc
    27901 tccacttgag aagactgggt cattgacatc agcaagagcg acaacatcac caacgatagg
    27961 agttacaagt gtttcatttt gaagagctgc tggcgcaact tcttcttttt cttcagccac
    28021 ttcagcttgt tttgcagctg cagttgcgtc tacttcatct tcgtaaccaa acatgtaagt
    28081 aagagcaaaa ccaagggcaa atgatacagc taccataaga aggtattgtg gaagttgtcc
    28141 gttaccaaca taaagcattg taccagggat gatggtgata ccattaccag taccagcaag
    28201 tccaaggata gaagccaatc caccaccgat tgcaccagca atcaatgaaa ggaagaatgg
    28261 tttacggaag cgcaagttca ccccgaagat agcaggctct gtaataccta ggaaggcaga
    28321 aagagcagcc gggaaagcaa gtgttttcag ttttggattt tttgttttaa caccaaccgc
    28381 aacagtagca gcaccttgag ctgtcatagc agctgtgatg atagcgttga atgggttagc
    28441 atggtcagca gcaagtaatt gcacttcaag caagttgaag atgtggtgca cacctgacac
    28501 gacgatcaat tggtgaaccc caccaatcaa gaaaccacca agaccaaatg gaatgctaag
    28561 aatcgctttt gtagcaataa ggatgtagtt ttcaacaacg tggaaaactg gtccaatgac
    28621 aaagagtcca aggatagaca tgaccaaaag tgtcacgaat ggtgttacca agaggtcaat
    28681 gacatctgga acaaccttgc ggacagcttt ttcaaattta gctccgacaa ccccgatgat
    28741 gaaggctgga agaacggaac cttgcaaacc aacaacaggg atgaaaccaa agaagttcat
    28801 cgctgttact tcaccacctt gagcaactgc ccaagcgttt ggaagtgagc cagagacaag
    28861 catcatacca agaacgatac caacggcagg atttccacca aatacacgga aggttgacca
    28921 cacaaccaaa cctggcaaga tgatgaaggc tgtatctgtc aagatttgtg tgtaagttgc
    28981 aaagtcacct ggaagtggca tttcaagagc gttgaaaaga ccacgcacac ccatgaagag
    29041 acctgtcgct acgataactg ggatgattgg aacgaaaaca tcaccgaaag tacggatagc
    29101 acgttggaac cagttccctt gtttagcaac ttctgctttc atgtcatcct tagatgatgt
    29161 tggtaagcca agtacaacaa cttcatcgta cattttgtta actgtacctg taccaaagat
    29221 aatttggtat tgccctgagt taaagaaagc accttgaact ttttccaagt tctcaatcac
    29281 ttctttattg attttctctt catctttgac catgacacgt agacgagtcg cacagtgggc
    29341 aacactattg acattttcac gtccgcccaa ggcatcgatg actttttttg caatttcctg
    29401 attgttcatt tgcaaaaatc tccttatata acattttgtt cttgtttgaa agcgatttta
    29461 ttcgccctta cgactattat tttatcatgt tttaaaaata tgtcaagcgt tttgcagaaa
    29521 aaatattcta tccacttagt gggcaagttt tagattgatt gtttttgact gtttcatcag
    29581 gaattccttg aaaaataagt ttgaaacctt ggttaaaaag tattttattt cattatcttt
    29641 cacattttcg taaaaatttg attgatttcc tgtatttatt tcatgataat cgtttgacag
    29701 ttttttctct tttttaatat aaaaggcttg cattttttat cgaaaacagt tactattaaa
    29761 agtgataaga tttttggagg aatgaatgga atggacaact gagcgtcgtt acagacttta
    29821 tcaagattgg acgcaagaag aaattcaaca tataaaggaa aatatggcac aatctccatg
    29881 gcatactcat taccatgttg agccaaaaac aggacttctc aacgacccaa atggcttttc
    29941 ttacttcgat ggcaagtgga tcctctttta ccagaatttt ccttttggtg cagcccacgg
    30001 tttaaaatct tgggcacagc tagaaagtga tgatttggtt cactttagag aaactggagt
    30061 caaagttttg ccagatactc cattagatag tcacggtgcc tactctggtt ctgccatgca
    30121 atttggcgat aacttattcc tattttatac aggaaatgtt cgcgatgaaa actggatccg
    30181 tcacccatac caaatcggtg ctttgatgga caaggagggt aagattacaa agattgacaa
    30241 gatcttgatt gaccagccag cagactctac tgaccacttc cgcgatccac aaatttttaa
    30301 ctttcagggt caatattatg ccattgtcgg cggacaagac ttggagaaaa aaggtttcgt
    30361 tcgtctctac aaggctgtca ataacgacta cacaaactgg caagcagttg gcgaccttga
    30421 ctttgctaac gaccgtactg cctacatgat ggaatgtcct aatctggtct ttgtagagga
    30481 acagcctgtc cttctctact gtccacaagg attggataag aaagttctag actacgataa
    30541 tatctttcca aatatgtata agattggggc ttcctttgac cctaaaaatg ccaaaatggt
    30601 agatgtgtct caacttcaaa acatggatta cggtttcgaa gcctatgcaa ctcaagcctt
    30661 caacgctcct gatgggcgtg ctctagcagt tagctggctt ggtttgccag atgtttctta
    30721 cccatctgac cgttttgacc accaaggaac cttctctttg gtcaaggaac tcactatcaa
    30781 agacgacaag ctctaccagt atccagtcgc tgctattaag gaccttcgtg cttctgaaga
    30841 agccttctca aaccgtttcc aaaccaagaa cacttacgaa cttgaactca acttggaagc
    30901 taatagccag agcgagattg tcttacttgc tgataaagaa ggtaagggac tttcaatcaa
    30961 ctttgacctt gtaaacggtc aagtgacagt ggatcgtagc caggctggag aacagtatgc
    31021 ccaagaattt gggacaactc gttcttgccc tatcgagaat caggctacta ctgctacaat
    31081 cttcatcgat aactctgtct ttgaaatttt catcaataaa ggagaaaaag tattttctgg
    31141 tcgtgtcttc ccacatgcgg accaaaatgg tatcctgatc aaatctggaa acccaactgg
    31201 aacttactat gaattagatt atggtcgcaa aactaactga tgtcgccaaa cttgcaggcg
    31261 tcagtcctac taccgtttct cgggttatca ataaaaaagg gtatctatct gagaaaacca
    31321 tccaaaaagt caatgaagcc atgcgagaat tgggctataa acccaacaac ctggctcgta
    31381 gtctgcaagg aaaatcagct aagttaatcg gcttgatttt ccccaatatt tccaatgttt
    31441 tctatgcaga attgattgat aaattggaac accaactctt caaaaatggt tacaagacca
    31501 tcatctgcaa cagtgaacat gattctgaga aggaacgtga atacatcgaa atgttggaag
    31561 ccaatcaggt ggacggcatc atttctggta gtcacaacct aggaatcgaa gactacaatc
    31621 gtgtgacagc gccgattatt tcctttgacc gaaacctatc gccagacatc cctgtcgtct
    31681 cctctgacaa ctatgctggt ggggttcttg ctgcccaaac cttggtcaag acaggtgccc
    31741 agtctatcat catgattaca gggaatgaca attccaattc gccaaccgga ctgcgccacg
    31801 ctggttttgc atccgtactc ccaaaagctc ctattatcaa tgtttccagt gacttttctc
    31861 ccgtcagaaa agaaatggaa atcaagaata tcttgacccg ggaaaaacca gatgccattt
    31921 ttgcttcgga tgatttgaca gctattctgg tcattaaaat cgctcaagaa ttgggcattt
    31981 ctgtcccaaa agagctcaag gtcatcggct atgatgggac ctactttatc gaaaattact
    32041 accctcaatt ggctactatc aagcaacctt tggaagagat tgcttgtctc actattgatc
    32101 ttctcttgca aaagattgaa ggcaaggaag tcgccacaac tggttacttc ttaccagtta
    32161 cgctattacc aggaaaaagt atttaaacac aagaaaactc agaccgattc gtctgagttt
    32221 ttatgatctt aaattttcga gatagcgctg ggctgtctct aggttaaagg ttttatctga
    32281 gatgaggcgc tctactaggg gagcaacttc agattcacta gccccagcta ggagagctag
    32341 ggatttggcc tgtagtttca tgtggccttg ctggatgccc gtacttacca aggctttgag
    32401 ggctgcaaaa ttttgagcaa gaccgatgga cacgataatc tgggctaatt ctctggcaga
    32461 aggatttcct agtagatcat gactgagagc tacacgtggg ttgaggccga tagagccacc
    32521 cttagtcgct acaggcatgg gcagggtcat ctcaccgacc aattcttctc tttcaaggtc
    32581 cagcgtccag cagctaagac cttgatagcg tccatctcga ctggcaaagg catgggcccc
    32641 agcttcgatg gcacgccagt cattaccagt ggcaatcaaa atcgcatcaa taccattaaa
    32701 aattccttta ttatgagtag cagctcggta aggatcagcc tgcgcaaact gactagccaa
    32761 cgcaattttc tccgcaatct ctcgtccttg atccttttgg cggctcaagt agcgaaaggc
    32821 gatgcgacag cttgcagtca ccagagaatc agtcgcgtag ttggacagga ttcccatgag
    32881 actctgtccc tgactgagtt cttctaagac tggtttcaag gcttccagca tggtgttgag
    32941 catattggca cccatggctt cctgggtatc gacatgaata taaacaacga gaaagtctgg
    33001 ttcgcctttt atctgctcga catgcagatc acgcgcccca cccccacgtt taacgataga
    33061 aggataggct tgattggcaa gctccaagag ctccgctttc ttgctggcaa tcttctcttg
    33121 cgctagttta ggattagcaa tttgataaag ggctacctgc ccaatcatct ggcgctgatg
    33181 gacttgtgca gtaaaaccac ctgcacgctt gatgattttg ctggcatagc tggccgccgc
    33241 aaccacagag ggttcttctg tcacataggg aacggtgtat tcctgaccgt tgacaagtac
    33301 ctccggaacc agcgaataag gcagagaaaa agttcccacc acattctcac tcagctggtc
    33361 tgccacagtc acactcatct gttcatcctt ctccagacta gcttgtctct caggactaag
    33421 gagcgcctga gcttttagca gctcgaggcg ctcttggtat gattttttag aaaatccatt
    33481 ccaacttatc ttcattattt ttcaaccttg ctataacggc gttggtggtc aagaatttca
    33541 accaaggcaa aatcttgatt ttcatagcca gcaaactggg cagagtttgt ttcatccaag
    33601 tttacttcct caaaaaagac cttttcatag tctgcaacgg atagggcagt tcgttggttg
    33661 agcttgttca agcggtcttt atccaaataa gcttcatatc cttcaaccaa ttcaccactg
    33721 aagaactcag ccacagctcc acttccgtaa ctataaaggg cgattttatc cccagctttc
    33781 aagctatctg tattttccaa gagagacaaa agtccaagga aaagtgaacc tgtgtagata
    33841 ttccccacct tttgactgta gagaatagac tggtcaaaat gcttttgtaa gaggtctttt
    33901 ttctcttgag gcaggctctt atccatgatt tttttcaagc cttttagcgc taatttagga
    33961 taaggcaagt ggaaacaaac agcagcaaaa tcatccaaag taagctggta gcgtttttga
    34021 tattcaagcc aagtcgtttt caaactatcc aagtattgtt gggtagaata gacaccattt
    34081 acataaggag ttgtcgagta atttggtcgc cagaaatcca tgatgtcacg ggtctgagct
    34141 acattgtcat tattaaaggc catcatgcgt ggattttgtg taatcaacat agctacactt
    34201 ccagcacctt gagttggttc tcccggagtt tcaataccat atttggcaat atcactggca
    34261 atgaccaata ccttggactc cggagaattt tccacatgca atttggcata atggagggca
    34321 gctgtcgccc catagcaggc ttctttaatc tcgaaactac gagcaaaggg ctggatgccc
    34381 agcaagccat gcacaaagac ggccgcagcc ttactctggt caattcctga ctcggtagcc
    34441 acaatgacca tgtcaacttc ttgtctttct tgctcagtta aaatagagtc actagcactg
    34501 gccgccaagg tcacgatgtc ctcagttagg ggcgcaatac tcaattcctt gagtaagagt
    34561 cctttactta atttttcagg gtcaattccc ctcgcttctg ctaagtcttg taatttcaag
    34621 acatattgac tggtcgcaaa accaatctta tcaataccga ttgtcatatt tacctctgtt
    34681 ttatcattca tgtaaaaaat cgttctatac tattttatca caaatggcag taaaagagag
    34741 aaaaaagact tgattcacca aatcaagcct cttattggtc atcattttaa agaatgatta
    34801 gttgctagag agttcaccga tataagtagc tttataagct ccattcacag ttatcagctc
    34861 ctggaggatc aaatttcctg agtaagtcct tcccatctca tctacaaatt tttgataaaa
    34921 ctgactggtc ggaatttctc tgacatcctt atcaaatgtc ttgtcaagtg ttttactaac
    34981 cttctcagca atcaattgat gctcttgcca tccactttga aactctgagc ccgaactaga
    35041 aaccatgact gggataaaca acaaggtcag tagacttaca gacaataagg aaaatagtag
    35101 acttcctgca aaactagaat cctagttcat gattgataat accaacaatc aaattcattc
    35161 gtaatccgaa gcgtttacga tgatttcgat aggttgttga aaacatttta aacgttttta
    35221 ctttggcaaa gatgttctca actttgcttc tctccttaga tagcgcatgg ttataggctt
    35281 tatcttcagc tattagcggc ttgaggttgc tggatttacg tggagtttgt gcttgaggat
    35341 atatcttcat gggcccttga taaccactgt cagccaagat tttaccagct tgtccgatat
    35401 ttctgcgact cattttgaac aacttcatat cgtggcaata gttcaccgca atattcaaag
    35461 aaacaattct ttcttggctg gtgacaatcg cttgaggttc catagaatga catttctatt
    35521 ttaccagaat aattggctag ttgatttttt taggacgatt tatttttacc tctgttgcat
    35581 ccacaatcac cgtattctca gcactaagat gagtttttga aatcgtaaca ccactttgaa
    35641 caagagttac ttcaacccat tggctccgac ggattaagtt gctttcgtgg ataccaaaat
    35701 cagccgcaat ttcttcataa gttcgatatt ctcgcacata tagaaagcgt tgtcaatcta
    35761 tttgtctcat ttttcagaaa attcttttat ttctgtaaag tctacgatac tcgatgtgtt
    35821 tttatataat gatagagtct gagaatcact gttccgctag ccattccaat agagattacc
    35881 agagccaaca tgacaaccaa ggtcgcactt gccagtgctt tattatagtc ccctgtcaca
    35941 aaaaaggcag ttgttcggta ggagagataa cctggaacca gcggtgccaa aatggccaag
    36001 ataaagacca cagcaggtgt cttataaaga atacttaaaa tctggctgac acaagaacca
    36061 ataatggctg caatgaaggt agctacaatg acattggtcg gttccttgag caagagatag
    36121 attagccaga cagtcatgcc caaaatccct ccaggtaaga gcatagaccg ttgcacattg
    36181 agtacgatta aaaaagtgat aatggcaaga aaacttgcta ctgcttgtaa taaaaaggtt
    36241 gttagtgtca tattagttca tcaataccaa ggcgacagaa gttcctgccc ctaaagcgag
    36301 ggtaatgagc agggattcaa acatcttact cataccagag tttatgtggt tggtcataat
    36361 atcacggacc gcattggtca aggcaatacc tggtacaaac ggcatgaccg caccagctat
    36421 aatcaaatct gccgttgaag gaaaacctgt gtagcgagcc caaaactggg caattatccc
    36481 aaagacaaag gctccagcaa aggctgtcac aaagggaatt cggataaatt tttccacata
    36541 gagggaaaag gcaaaaccaa ataaggtcgc cactcctgcc ccaagtgcgt cgtagatatt
    36601 tccgctaaac ataactgaaa agaaaggagc actaaaggtc gcagccagag ttacctgcaa
    36661 cttagtatag ggaaggggtt gagcttgcaa ggccgtcaat tgcttaaagg ctgtttctaa
    36721 gtcaatctgc cccccaacta gctgacgaga aatctggttc acatcgcaga ctttttcgat
    36781 gttataagaa gaggaggtca cgcgcttcat gcgcgaaata ttggtatttt caatagagaa
    36841 aaagatagcg gcaggcatgg caaggacatt gcaatccaca atcccctgcg aatgcgcgat
    36901 tcgaatcatg gtatcttcta cacgatggat ttctgagcca cttttaagga gaatagtccc
    36961 cgctagcata atcacatcaa tgacggcatt taattctttt gattcttcca tgctttcctc
    37021 cttttatcaa ctccctctat tctatcacaa atctggactc aaaaaaaatc tttgccatga
    37081 aatcatgaca aagattgatt actcattttg attatccatc tgcttttaag gagtagctga
    37141 agttgtttta ggtttgtaga ttgaaatctt gactctagtc ttatttaggt ctaccttttc
    37201 acctgctcta ggactttgtt caacaaccat gccttctaca ctacctgcag gcgctgtcgt
    37261 cacttctaca acttctatat tagcttcctt aatcccaaca atttgaatca aattgttctt
    37321 agtaaactcc aagctggaac caatgtaact cggcatggca acacttgtaa cttttttagc
    37381 tactgtcaag acaatttgag taggtttact cacatcataa gtcgttccgg cacctggact
    37441 ttgtttcata atcgttcctg gttcgctttc gctggactct tcttcctcta tcttaatcaa
    37501 attctcagga accttcttct gcttgagttc tgagattact tctgtagagt tccgtccaat
    37561 atagttccct aattgaatcg tcgtagcttt tttagctact gtcaaaacaa tttgagttgc
    37621 cttgctcaag tcataggtcg taccttctgg tagactttgc ttcaggaccg ttccagcctc
    37681 actctcattc gactcttctt cctcaatttt aatcaaatta tctggaactt ttttctcttt
    37741 taattccgcg ataacatcag aagatttccg gccgacataa ttactaattt ggaaggattg
    37801 tttgcctgat gagacaacca gattgatttt cgttccttct tttcgaccag ttccagcgcc
    37861 aggatctgta cggataatcc gcccttcttc caccttttca ctagcctctg tcttctcctc
    37921 accaatctca aaattggctt ttttgagcgt tgccttggcc tctgcaactg tctgacctgc
    37981 cacatctgga atggcaatgg ttgcaggagt tctggatagt atccaaataa gagaagctgc
    38041 caccaataca aggctggcca acaaaatcag gtaacgcatc ttaaatctat gttttttcgg
    38101 tgcttgtggt tggtaagttt cctctgtcac agcctggctt gggtttttga ttgatttgtg
    38161 ttctgtctgc gcttgaacct taggaataga tgtcaaggta ctctgagaaa ccttcggcaa
    38221 ggtcttggta tctgccttgc tcgtttcatc aaagattaac ttactttcat ttctacgatt
    38281 gtaggacaag ctactagaca agtccacata catctctgaa accgagcggt agcgattggt
    38341 caacttttta gcagttgcct tgataataac attttctaaa gcctgaggta cagatggatt
    38401 ttctgcaata acggacggca ggggtttctg gaaatgctgg agggcaatgg tcaccgcgct
    38461 atccccgtca taagggatat ggcctgtcaa catctcatag aaaataatcc ccatggcata
    38521 gatatcactc tgcacagtcg ccttcgaacc acgcgcctgc tctggtgaca agtaatgaac
    38581 tgagcccaac atcgagttag tctgggtcag acttgtctct gcaaaggcta cagcaatccc
    38641 aaagtctgtg accttggccg tcccatctgg tgtcaaaagg atattttgag gtttcaagtc
    38701 cctgtgaaca attcctcgag tatgggccaa gcgcatagcc aagagaattt gtcccatgat
    38761 acggactgct tcttcattag aaagaggata atgttccttg atatagcgtt tgaggtctag
    38821 tccagcaaca tactccattg caagatactg ttgaccgtct tcctcgccaa tatctgttat
    38881 ccgaacgata tgaggatggt ctagatctgc catagctctc gcttcacgct gaaaacgagc
    38941 tacagctatc gggtccgtct ggtagttggt cctcagaacc ttcactgcca cttcttcccc
    39001 atctaagatt aagtctttgg ctaggtagac atccgccatg cctcctcgac caatctgttt
    39061 gacaatccga tagcgtccgg caaaaatctt gccgatttgg atcattcttc atcctcctcg
    39121 ttcatagaaa caagggcaac cgtaatgttg tctaaacctc ctgcactgtt agcaaaacga
    39181 acaagtgtct ccgttttatc tgctaaagga atatcactgg ttacaatatc acgaatctca
    39241 ctgcctgaaa tcatgttggt caagccgtca ctattgagca agagatagtc acctgactca
    39301 aggataactg tcccaaaatc aggctgaatt tcatcttttt gcccaataga ctgggtgata
    39361 atattttttt gcggatgagc ttctgcctct tctggtgtca attgaccagc cttgagcaat
    39421 tcattaacca aggaatgatc gctcgtcaac tgatggtatt cttctccacg aatcaagccg
    39481 atacgcgaat caccaatatg agcatagata gcctgattat caataatagc aaggacttcc
    39541 aaagtagttc ccatgcctct gtaagcttca tcctgaccaa gctggtgaat cttttgattt
    39601 tcaatttcta ggtaatgggc gaaccattca cgcacttcat tgactgtatc gatctgggta
    39661 tcaacccaag ctacacccag gtctgtgacc gccatttcac tagcgatatt ccctgcacga
    39721 tgacctccca tcccatcagc taaaataatc atggtacgtc cagctctatt gacatagtgg
    39781 ttgacatagt cttggttatt tgttcgtttc tgaccaacat ctgttaataa tgaaatttcc
    39841 atgtgtcagt tccttcctaa tccgatatct tgcgaaattg actgatgaag aatccatcac
    39901 ttccatacaa ttcaggtgta atgaggatac agccgtcttt catgatatcc ttacattcat
    39961 gttctagttt tacctgctcg aactcgggat gactctctaa aaaggcctta acgacttgaa
    40021 aattctcctc tgagacgata gtgcaggtgc tataagttat tataccacct ttgcctagta
    40081 tttgacaaac actacctaat atttctaact gaatttcctg caaggacgcg aaatctgccg
    40141 tttctttatt gtatttgata tctggttttc ggcgcaaaag accgattcct gaacaaggag
    40201 catccaccaa aatcttatca aaggaatcct ggtcaaaaaa ctcatgcacc tttctggcat
    40261 ccaatttttg agtttgaacc cgatctgcaa ctcccagacg ttgggcattt tcttgaatta
    40321 aatccaactt gtggtcgtac aagtccagag cagtaacctg acctgtcgta agataagagg
    40381 ctatatgggc tgttttccca cctggagccg cacaggcatc aagcactcgc tcatcacctt
    40441 gtaaatcaag cgtcggagca accagctgac tggactcgtc ttggatggta atggctccat
    40501 ccgcaaacaa attatgccct gcaaaatgcc cttgctcctt aaccagacca gtggttgcta
    40561 aaagggaatc attcgcctcc aacaaggctt ggatttcctc ttttcgactt aggtctgtta
    40621 cacgaatact ggctttgttt cgcactaaca ggctttcaaa gatggctttt gctctctcct
    40681 ctccgtattc ttccttgagt ttggtaacta gccaaactgg gagagaatag gcaatggagt
    40741 cacgcttgtt ttttcgcttg atgctagcaa tatctggcca gccttcacgc aagatacggc
    40801 gaaggacagc gttgaccaat ttttcactgc cttttttacg gagtttggcc aattccactg
    40861 cttcattgac cacagcatga tctggaatct tgtccaaata gcggagttgg taggcactca
    40921 tgagaagaag gacatagagc cagctgtcta actggtctct gtcttcgata aagtgggata
    40981 agtaccattc cagagtcagt ttacgggcta ccgttccata gactagctcg gtcactaagc
    41041 ccttgtctgc tgcagagagc tgactcccct tgaggtgttt atttaaggca atatttgaat
    41101 atgcttgatt cacaaaaaca tcctctagca ctgctagagc taaacttcta gccgtttcta
    41161 ctttagtcac caaatcgttc tcctacagtc aatgtacgtc caactccgtt gaggaaggaa
    41221 gcaatgtcca tcttaggctt accagctggc tgcacttgtt tgagggatag agccccttca
    41281 gccgttgcga caatcaattc tttcttgccg atagagagaa tctcacctgg atttccctga
    41341 tcttctactg gtagggcttc ataaatctta aagcggtcgc ccttaaggaa agtatgggca
    41401 acaggccagg ggttcattcc acgaatttgg ttaaagagtt gacgattggt tttgttccag
    41461 tccagttttt cttcctctgg ctttatattt ggagagaagg taacctgact cgtatcctgc
    41521 ggttcaggtt tgatatcacc agcaatatag gcaggcagag tgtccaaaag caaatcacga
    41581 ccaactagcg ccaatttttc aaacaaggtg ccaacattgt cctcatctgt gatcggaatg
    41641 ctgcgacgaa aaatcatatc tcctgcatcc atttccttaa ccatttccat gatggtcaca
    41701 ccagcttcct catccccttg aatcaaggca taatggatag gcgcaccacc acggtgtcta
    41761 ggaaggaggg aggcatgaac gttgacagca aagtccatgc tatcaaggag tttgcttggg
    41821 agaaactgcc caaaagcagc agtcacaatt ccatctgctc ctagcttcat aagttcttcc
    41881 atctctggac ttccagataa tttttcaggt tggtagatag atagtcctgc ttccttggca
    41941 gcctgcttga ctggggtttc ttggataact tttttacgac caacagcacg gtctggctgg
    42001 gtcacaacgg ctagaatttc gtaacggtca tctgtcaaaa gtccttttaa gactgttgct
    42061 gaaaagtcgg gggtccccat aaagattagt tttgtcatat cttctccttc ttataaaaat
    42121 tgctgcggct catggtcaat gctgagacgg agctcactat tttcccgttc ttgagtcaag
    42181 gctaaaacct ggttgagggt cggccccagc tcatcttcta aacggtattt aattaaaatc
    42241 tggtaatgat agaggttgtg ggtacgggca atcggttttg gcgttggccc cagaatggga
    42301 ctggtctctg acaagcctga ccgcaaaatg ttcatgactt cataggcacg tttgaaaacc
    42361 tcttcttctt tcttgtgaga aagggtaata ccaatcgtga aatagtaagg tggatagccg
    42421 agttgtcgtc tgattcccat ttcataggca taaaagcctt cgtaatcttg atccttggca
    42481 aatcgaatag catagtgctg cggattgtag gactgtatca agacttgacc tgccttttca
    42541 gcccgacctg atcgacctgc cacctgagtc aagagctgga aggttctctc agaagaacgg
    42601 aaatcaggca gattcaaggc cgtatccgca tttagaactc cgactagggt aacattggga
    42661 aaatccaaac cctttgcaat catctgagta ccaagtaaaa tatccgcttc ccctcgccca
    42721 aactggtcaa gcaaggcttg gtgactgcct ttctttcgag tcgtatccac atccatcctc
    42781 agaatgcgag cttggggaaa gagttctgct agctcatcat aagccttctg agttcccgtt
    42841 ccatagtaac gaatactgtg gctcttacag ttaggacaga cctgaggaat atccttcgag
    42901 aaaccacaat aatggcagtt catagtcttg gtatccatat gcaaggtcag agaaatatcg
    42961 cagttgggac aagtatccac cgtcccacac tcccgacaca tgacaaagct agaataacca
    43021 cggcgattga gcatgagaac cacctgctct tttttaacca gacggtcttg gatagcctct
    43081 agcaaaggag gcgtaaagtt tgacgtctca ttttgtccga tatagtctcg aaagtcaatc
    43141 acttgaacct cagggattgt agccaaagga ttggcacgtt gggttagacg taagtgttga
    43201 tagacgcctt tgccagcacg tgcccggctc tctaagctcg gcgttgcaga tccaagtacc
    43261 agagttgctt gattatactg agcccgtaaa atagctacct ctctggcatg gtaacgggga
    43321 ttgctgtcct gcttataagc cgcttcatgc tcttcatcaa taatcatgac acccagattt
    43381 ttcagaggag caaagatagc agatctggca ccaacaacaa cttgggcatc gccacgctcc
    43441 accttgcgcc attcatcata cttttcgcca ttggataatc ctgagtgaag aatggctacc
    43501 ttgtccccaa aacgtgctat aaaacgctcg gtcatctgag gagtcaagga aatctcaggt
    43561 accagcaaaa tagctgtctt gcccttatcc agggcacctt ggataatctg caagtaaacc
    43621 tcggtcttcc cacttcctgt aatcccttga agtagaaagg gaggttgaga actgccaata
    43681 gaactcacaa ccgcatcacg cgcctgtctt tgttctggat ttaactccaa aggtctactt
    43741 gcttcaattc cttcaaaata agcagccgag cgttgaactt ccttttggac tatggtaaca
    43801 gcaccttgat ccacaaagaa gttgacttgc tctcgcgagt aggactctaa caagctagcc
    43861 aaggaagcgc tctctggatg agacagcaga taatctctca gttccaactt tttcttggca
    43921 cgtgtagaaa tctcaacacc ttctaattgg gcatggtcaa cctcatacca agactgggtc
    43981 ttgaccttct tttgatcgac tgcctgatat tccagaccaa gcaggccttt tctagtcaaa
    44041 cgcatcattt cagcttgctt acctaaatcc agagaagaaa aggctagcga atcttctgaa
    44101 tcaaacaggc gtactcgttc ttcctgactc aagccttcca gaggatagag aatcttgtca
    44161 tagctagaat tcagaaatcc cggaagcatg gccttgagga tagagatttt gtaggagaag
    44221 acagatttgc gtaactcctc agccagccag agttgttctg gcgtgagaac aggagaaaaa
    44281 tccagcacct ctgcaatatc ttttaaatct tgctccatct cttctccatc tgattgggac
    44341 tccaaaccaa gaacaatccc ttgaatcagg cgattaccct taccaaaagg cacatgaacc
    44401 cgcatcccaa cttccagcat tccctcaaat tcctccggaa tcctgtaact atagggctgg
    44461 tccgtctgca tcaagggcac atctacgata atcttagcta gggccatctt ctcacctcct
    44521 ccttgtcagt acattcttgc aatagaaaaa ataagattga gtccccccaa ccttaaattt
    44581 tttcaccatc ttctttttct ttagcaattt gctctttgat tttcttttct tcttcttctt
    44641 tgcggcgttt ttcttcttcg atacggcgac gcactgcttc acgttttcct tctggatctg
    44701 ggtgaattgt aacgtttcct gattcgattt cttctaaagc gcgaagagtt gatttttcag
    44761 acttgaaacc ttgagttgct ggggcacctg cttccaattc gtgggcacgt tttgcttcca
    44821 agattacgag tgaatatttt gaaggaacct tgtcgagcaa ggtatcaata gagggtttta
    44881 acatcatttg cttgtaccta ttttctaaat tttatcgggt agttggagat tttggtaaca
    44941 tctcctgata gtgaccaatg acacgatcca cacagaagtg ttctgcttca atcacacatt
    45001 tgacacgttc agcagctagg ggcacctgat cgttgacaat cgcataatca tactcacgca
    45061 tgagggcaat ttcttccttg gccttttcga ttcgttgggc aatcacttct gcactatctg
    45121 ttccacgacc taccaagcga tcttgcaatt catccaaatc tggtggtgtc aggaagataa
    45181 agacagcatc tggaaccttt ttcttgacct gaagagcacc ctgaacttca atttcaagga
    45241 aaacatcgat tcccttgtcc aaggtttcat tgacataggt cagaggagtt ccatagtagt
    45301 tgccgacata ttctgcgtat tccaacattt gtccttgacg aatcagctct tcaaattctt
    45361 cacgagtacg gaagaaatag tcaacaccgt ccacttctcc aggacgttgt gcgcgtgtcg
    45421 tcatcgatac agaatattga aattggtttt cagaactctc aaaaatctct cttctaaccg
    45481 ttccttttcc aacccctgaa ggaccagaaa aaacgattag taagcctcgg tctgccattg
    45541 tgtctccttt tagtcaatct gtgaaataac atttctctag aataatggca aaaagccaga
    45601 ttatccttta cagtctttct atctagtgta acaaaaaagc agtaattttt caactgctct
    45661 ttcttattta tttagcataa tctactgcac gaagctcgcg aatcacggtt accttgatat
    45721 ttcctggata atcgagattg ttttcaattt tcttacgaac tttgtgagcc aagattgtga
    45781 ctttgtcgtc cttgattttt cctggattga ccatgatacg aatttcacgt cctgcttgaa
    45841 gggcaaagct agtttgcact ccttcaaagc cgttagcaat ttcttccaaa tcatggagac
    45901 gcttgatgta gctttcaaga gactcactac gagcacctgg acgggctgcg ctcaaggcat
    45961 ctgctgcagc gacgataact gctatcacgc tctcagcttc aacatctccg tggtgactag
    46021 caatcgtatt caccacaact gggggttcct tgtacttacg ggccaattcc ataccgattt
    46081 caacgtggct accttcaacc tcatggtcaa tggctttccc gatatcgtga aggaatccag
    46141 cacgacgggc aagagccgca ttttcaccaa gttcgctcgc catgatacca gccaacttag
    46201 ccacctcaat cgaatggcgc aaaacatttt gtccatatga agtacggaac tgcaaacgtc
    46261 ccataatctt catcaagtct ggatgaaggt ttggcgcacc aatttcatag gcagcagcct
    46321 caccgtattc acgaatctta ttgtcaatct cttgacggtt tttctcaacc aactcttcga
    46381 tacgagctgg atgtatacga ccatctttga gcaacatttc catagtcata cgggcaatct
    46441 cacgacgaat cggatcaaat cctgacaagg tcaccacttc tggtgtatcg tcgataatca
    46501 catcgacccc tgtcaaactt tcaaaggtac gaatgttacg accttcacga ccaataatgc
    46561 gtcccttcat agtatcgtct ggcagatgaa ctgttgagtt tgttgactcc gctacatatt
    46621 caccagcgat acgttgcata gcttgaacca agatgtcctt ggccattttg tcagaacgtt
    46681 ccttgacctc ttgctcagct tcgcgaatgc gactggcaat ctccctggtc aagttttcct
    46741 ctgtctgaac caagataata tctcgtgctt ctgcctgaga cagagcacca atacgctcta
    46801 gttctgcttc tttttgtctt tcgacttcct ctaattgctc ttcacgcgca tcaaggtttt
    46861 tcgctctatc agaaatactt tgttcttttt gttcaagtgt ttgttcttta ctcgtcaaat
    46921 tgtcgtcctt acggtcaagg ctagtagctc tctctgtcaa acgactttcg atttgtttga
    46981 gttcttgacg ttctgatttg aattcagcgt ccacttcttc acggtatttt ctggcttctt
    47041 ctttggcctc caatagtgct tcttttttaa gagacttgct ttcacgtttg gcttcattaa
    47101 caagtaaatc cgcttcacgc tcagcttgtc cacgtaaatt agttgcttct tgttcagcat
    47161 ttaaaagcat caactctgca gcttcctgag atgatttcat cttagctgag atgctgacat
    47221 atccaatgac taaaccaatg atgacggcaa aaacagcaat cgcaagcgac atgatttcca
    47281 tgtttttacc tcattttatt gttattccga atgacataca ttcttttaca ttctaccata
    47341 aaaaagtgat tttcacaaac ctaaaataga atatgttttg gggaaattag tctgaatttt
    47401 aggattacac ttccttggtt ttttaaggag ataagtcagt gccgctatca aaaagttcca
    47461 ccgaatttct actgctatgg attttctatt gttgtgccaa atagtgttcc actagattca
    47521 aacattttgc tttcaagtct ttgaaaattc actttaggaa atcacagctt atcttcaaga
    47581 tcaaatttgt cataaattaa cttttttatt tagttgtatc aatttatttc ttaagtatta
    47641 atttatcctc atcgaaagct tttaaaatat actcattaat caatttatta tcttcttcat
    47701 tttttgaaaa ataagtttta atattattgg gagttctatg ttctagtaga cgatggataa
    47761 catcatcact tctatcatgg aaccaggtcc aatctacttc aggataaagt cctcgaatat
    47821 cttcttcaat atcttttaaa atctcaaaat cagaaaaata tccttttcta cttaagttgt
    47881 ataaatctga tacagacttt tctcttgggt ctgggaaagt tttaaccccc tcaactcttt
    47941 tatcattaat tcttttaatc aaataatggt agattttatt ttgtatctga ggaaaatca
//
LOCUS       DAVLGK010000010        45697 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLGK010000010 DAVLGK010000000
VERSION     DAVLGK010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45697
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.010"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(1..333)
                     /locus_tag="VXE01_000631"
                     /pseudo
     CDS             complement(1..333)
                     /locus_tag="VXE01_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            458..916
                     /locus_tag="VXE01_000632"
     CDS             458..916
                     /locus_tag="VXE01_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV0749595.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            929..1537
                     /locus_tag="VXE01_000633"
     CDS             929..1537
                     /locus_tag="VXE01_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749596.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSRLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            1608..1940
                     /locus_tag="VXE01_000634"
     CDS             1608..1940
                     /locus_tag="VXE01_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749597.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            1951..3366
                     /gene="ply"
                     /locus_tag="VXE01_000635"
     CDS             1951..3366
                     /gene="ply"
                     /locus_tag="VXE01_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV0749598.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            4247..4963
                     /locus_tag="VXE01_000636"
     CDS             4247..4963
                     /locus_tag="VXE01_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0749599.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            5087..5536
                     /locus_tag="VXE01_000637"
     CDS             5087..5536
                     /locus_tag="VXE01_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0749600.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIDQELNITKSVASNLVKRIVQNCLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            5575..6396
                     /locus_tag="VXE01_000638"
     CDS             5575..6396
                     /locus_tag="VXE01_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749601.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPA
                     SMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGSIMAIWAIGKILGHSEYWLWAVLVVVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            6403..7434
                     /locus_tag="VXE01_000639"
     CDS             6403..7434
                     /locus_tag="VXE01_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0749602.1"
                     /translation="MDFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPAQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSIGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQRVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIACALLKDASLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSIIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            7499..7861
                     /locus_tag="VXE01_000640"
     CDS             7499..7861
                     /locus_tag="VXE01_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEV0749603.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGEKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFLQAPYYVPERITITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            7858..8361
                     /locus_tag="VXE01_000641"
     CDS             7858..8361
                     /locus_tag="VXE01_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0749604.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSAGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            8475..8921
                     /locus_tag="VXE01_000642"
     CDS             8475..8921
                     /locus_tag="VXE01_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0749605.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            8926..9600
                     /locus_tag="VXE01_000643"
     CDS             8926..9600
                     /locus_tag="VXE01_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749606.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGTAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            9856..10044
                     /locus_tag="VXE01_000644"
                     /pseudo
     CDS             9856..10044
                     /locus_tag="VXE01_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647592.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
     gene            10294..10593
                     /locus_tag="VXE01_000645"
     CDS             10294..10593
                     /locus_tag="VXE01_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV0749607.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            10590..10907
                     /locus_tag="VXE01_000646"
     CDS             10590..10907
                     /locus_tag="VXE01_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV0749608.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     SNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            10923..11549
                     /locus_tag="VXE01_000647"
     CDS             10923..11549
                     /locus_tag="VXE01_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV0749609.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKDKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            11582..12343
                     /locus_tag="VXE01_000648"
     CDS             11582..12343
                     /locus_tag="VXE01_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0749610.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHVINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADIVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(12479..13906)
                     /locus_tag="VXE01_000649"
     CDS             complement(12479..13906)
                     /locus_tag="VXE01_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0749611.1"
                     /translation="MKTTNKVAIYVRVSTTSQVEEGYSIDEQKDKLEAYCKIKDWKIY
                     DVYVDGGFSGANTQRPELERLISDVKRKKVDIVLVYKLDRLSRSQKDTLFLIEDVFAK
                     NDVAFISLQENFDTSTPFGKASIGMLSVFAQLEREQIKERMMLGKEGRAKNGKSMSWT
                     TIPFGYDYSKETGVLSVNPTQALIVNRIFTEYLNGKPVVKIIRDLNAEGHVGRKRPWG
                     ETITKYLLKNETYLGKVKYKDKVYEGQHEPIITQELFDLVQLEVERRQISAYEKYNNP
                     RPFRAKYMLSGLMKCGYCGASLGLRYTRKDKNGISHHKYQCRNRHSKDLEKRCESGWY
                     SKEELERVVIKELERIKFDPKYKNETLAKKEETIKVEEIKKQLERINNQVSKLTELYL
                     DEIITRKELDKKNDKIKTERQFLEEQLENQKSNVLSIRKRKLTRLLKDFDVEKLSYED
                     ASKIVKNIIKEIIVTKDGMSITLDF"
     gene            complement(14073..14273)
                     /locus_tag="VXE01_000650"
     CDS             complement(14073..14273)
                     /locus_tag="VXE01_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749612.1"
                     /translation="MSNESRPMEVIKHNLDCKCHRRREWIRVNDKWHAIEFSVDDPNE
                     PPMTEEEKANVALILQQHLSKE"
     gene            complement(14275..15042)
                     /locus_tag="VXE01_000651"
     CDS             complement(14275..15042)
                     /locus_tag="VXE01_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0749613.1"
                     /translation="MKVENKEIFANNLSFYMEQKGVDRNTLCADLDLKYTTVRDWLKG
                     ITYPRIGKIELLANYFNINKSDLIENKIFTAQPSDSLLEEITNTARKLNTDNKKIVLR
                     TSEELLESQENEEETKINEVSENIIRLDDYRQTTYRRVTGVVSAGSGSIQDDDLDMEV
                     SFYEDEIPDDYDAIAYVVGNSMEPKIKNGDYLFIKNTQQVDYNTIGIFQVDGANYVKK
                     LRQGYLESLNPDYEDIHLDESNDIRTIGEVVSVYREK"
     gene            15210..15485
                     /locus_tag="VXE01_000652"
     CDS             15210..15485
                     /locus_tag="VXE01_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015973618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749614.1"
                     /translation="MNTLNEKAINIFKAVAKETLIQGTYEENFLYSQLETFSTNCRQF
                     AFGWTELADEIERQERYLLDSGFTQEEIDDIRFDAAFAGMQDKMNVA"
     gene            15653..15859
                     /locus_tag="VXE01_000653"
     CDS             15653..15859
                     /locus_tag="VXE01_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749615.1"
                     /translation="MFLDGVERVEFINNFKDKDCEVILSFNERVENNPFPLNEVSLLE
                     KLFGQASNGQSLRDIVLQTLEDGN"
     gene            16050..16256
                     /locus_tag="VXE01_000654"
     CDS             16050..16256
                     /locus_tag="VXE01_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001171134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0749616.1"
                     /translation="MSKMTLKTLRTLKNWRQSDAAAAVNVSVDTWGHWERGITEPSVS
                     KAYQIASVFDVSVDDIIFLPDIAV"
     gene            16329..16691
                     /locus_tag="VXE01_000655"
     CDS             16329..16691
                     /locus_tag="VXE01_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0749617.1"
                     /translation="MQYIIRNTHGNYTSLNNAYAQDKRLKATTIGILTVILMNKSDWV
                     VYPDEIARRLGISRRTVDEHFKLLEKAGYLRVYRLGLGRGKGVTVYRFFSDMPISDDY
                     FEYLKTNLEKELSTDNGV"
     gene            16971..17153
                     /locus_tag="VXE01_000656"
     CDS             16971..17153
                     /locus_tag="VXE01_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749618.1"
                     /translation="MRPRKYPYSFKPNLMNILDSRFYTRLIVETEDGAKKIAEVTLDD
                     VTSATGYVVRLRPNYD"
     gene            complement(17150..17374)
                     /locus_tag="VXE01_000657"
     CDS             complement(17150..17374)
                     /locus_tag="VXE01_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014334617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEV0749619.1"
                     /translation="MGKNQHVVPAKNGGWNVKGAGNSRATVHTTTKNEAKNIARQISR
                     NQDSELIIHGKDGKIQSRDSHGKDPFPPKG"
     gene            17491..17634
                     /locus_tag="VXE01_000658"
     CDS             17491..17634
                     /locus_tag="VXE01_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749620.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     KTV"
     gene            17701..18498
                     /locus_tag="VXE01_000659"
     CDS             17701..18498
                     /locus_tag="VXE01_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001056933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEV0749621.1"
                     /translation="MNMNLNTNEILTTTEYDMFRKISNRKITENPKLEEELLSEGQRQ
                     PILVNEKMEVIDGQHRLYYLRKHRKPVRYIIDPTANFKTVISMNTSAVNWALQDYVYS
                     FALEGDPEFVKLAKFLDENELLSDKMVIVAGSGRRDGTAAHVVKKLKKGDYVFSNEKQ
                     LREFCKFYERVLNETKLPNKPFLQSVLWTLYTTSVFDENRMLTQLKKSDLTSEDIEGF
                     AKKKLLLTFLELYNGRWSDDHPSLIQYFINRKGSLTIPSLPKQDEDN"
     gene            18516..18653
                     /locus_tag="VXE01_000660"
     CDS             18516..18653
                     /locus_tag="VXE01_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749622.1"
                     /translation="MKVTVYVYGRKLEPDEPIIIPENHRFYDIWNGIVNEMLDNEEDV
                     A"
     gene            18653..18874
                     /locus_tag="VXE01_000661"
     CDS             18653..18874
                     /locus_tag="VXE01_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749623.1"
                     /translation="MKLLTKLKLRLEGVLKSVNLDWKEVAVELMNDLFEERKRRFAFE
                     QENYDLKQELAAYKYKENFDIKARLQGEM"
     gene            18875..19129
                     /locus_tag="VXE01_000662"
     CDS             18875..19129
                     /locus_tag="VXE01_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749624.1"
                     /translation="MYIISIYVKNTETGNEDFSLIGRDFLPTGHQDYIARVFGTKEEA
                     IDYLKSISYIASGVHGNDWVYQNEKLPEIESRCRIWKVGE"
     gene            19142..19402
                     /locus_tag="VXE01_000663"
     CDS             19142..19402
                     /locus_tag="VXE01_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749625.1"
                     /translation="MFKALKTIKKIKQLQKEMHAFSLAFLALQDMGLMPETERSKAKA
                     QTMHDVSRVLKDVLDGKSVDEAIKRLNSEVKAEEVGQKDDQN"
     gene            19701..19886
                     /locus_tag="VXE01_000664"
     CDS             19701..19886
                     /locus_tag="VXE01_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749626.1"
                     /translation="MKKRLYYKKWKQELREAMREEIDGDYLTEKMVRKMSISDMSHYL
                     NRLALEEAGYCGTMFNY"
     gene            19904..20656
                     /gene="bet"
                     /locus_tag="VXE01_000665"
     CDS             19904..20656
                     /gene="bet"
                     /locus_tag="VXE01_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HEV0749627.1"
                     /translation="MTNNQLATQTKRNITTDPSLLTGADIKKYFDPQNLLTEKQVGQA
                     LALCKGRNLNPFANEVYIVAYTNRNGGKEFSLIVSKEAFLKRAAQCKDYEGFEAGVVV
                     VDSEGVMHERKGAIMLPEDTLIGGWARVHRKNFKVPVEIFVSREEYDKKQSTWNTMPA
                     TMIRKVALVNALREAFPEDLGNMYTEDDGGETFDRIKDVTPQESREDVVARKMAEIEQ
                     FNKEQEANHADPEPTQNEDPIQGELLDGELEY"
     gene            20666..21730
                     /locus_tag="VXE01_000666"
     CDS             20666..21730
                     /locus_tag="VXE01_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEV0749628.1"
                     /translation="MQELQVKVTQAQVEIIDREKFEQNINEVAAKYQNYTVTAATIKD
                     DKQTLADLRKLDKQVSDERIRNKKVLSEPADEFDKYVKNAIQPLKDIITKIAGDVKEF
                     EEHQKAVRIDTVKGYLANKSAEYMLDPRLFDEKALEYVKASDFMADGVTLKKATMKSL
                     DDMVTFEFQKQQEFEKAKSAISGLCAEYGMTDSPYIRQLKDLTLAEVFGQIKADYEFE
                     KQKEEIRQAQERAERESQELLAAQQTKQQEQAPKSTETPNFDPETGKILDGEQIPQNE
                     QNSLRGAENDLKRYTQKMTLEVYFVDTAEKDRFKAGLSQLGFDFKKNYQVSGYQRIEP
                     LTQAELNEQWGGNHGHQKNI"
     gene            21708..22031
                     /locus_tag="VXE01_000667"
     CDS             21708..22031
                     /locus_tag="VXE01_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749629.1"
                     /translation="MDIRKISDSVAIYSDGKKLHVIHNLGDEFILDFKVGEDSVWNLN
                     GQVVEIIDMIEPVFKVFSFCSKSGEGMQRLKHAIVHFEKFEQYIRDNQEDLMIWWHNP
                     GGEYD"
     gene            22024..22359
                     /locus_tag="VXE01_000668"
     CDS             22024..22359
                     /locus_tag="VXE01_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HEV0749630.1"
                     /translation="MIKTVFFSCDYPHHEAIDDQINSWLAENPGIKLIDIKFQSNVSA
                     VADSGVSAEYWHTSALIIYKVPSENNISSINSNGLGFIISCEKCGSLSIIKGKDVGQN
                     VCYECKGEK"
     gene            22454..22870
                     /gene="ssb"
                     /locus_tag="VXE01_000669"
     CDS             22454..22870
                     /gene="ssb"
                     /locus_tag="VXE01_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0749631.1"
                     /translation="MINNVTLVGRLVAPPDLRKTPNNVSSLQGTLAVNRNFKNENGER
                     EADFINFQAWRGTADIIAQYCSKGSLIGIIGRLQVRSYEKDGQRRYVTEVIAESVALL
                     ESRNSQHGQGNSFQNGNSSPFTDPNPFDLPNDGLPF"
     gene            22880..23386
                     /locus_tag="VXE01_000670"
     CDS             22880..23386
                     /locus_tag="VXE01_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0749632.1"
                     /translation="MSKIKILDACCGSRMFWFDKNESHTIFMDIRQETFEIHDKKVNV
                     DPDIIGDFRDMPFEDNTFNLVVFDPPHLKWAGPNSIMKAQYGQLDKVTWSEDLAKGFE
                     ECLRVLKVGGTLVFKWSDRQINVKKLLEVIPFKPLFGQQRGTTHWLTFVKFEEDKNGV
                     DGLGGLET"
     gene            23352..23561
                     /locus_tag="VXE01_000671"
     CDS             23352..23561
                     /locus_tag="VXE01_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749633.1"
                     /translation="MEWTDWVDWKPETKTDIKTKIENDGYTFPHYDKKNNGVKYVIST
                     LDIKRDCLRLGVPFEDVYPLQTTLF"
     gene            23575..23904
                     /locus_tag="VXE01_000672"
     CDS             23575..23904
                     /locus_tag="VXE01_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749634.1"
                     /translation="MASKINATERIAIIIEKQKIEVVTTLNYDMSISFDNKDTAPTLD
                     DNGDLFEPVYKCKVKAIPKNDVFFTSLTRVKSNIKTLQEVKKFFEFVNENRENLFEMA
                     GFKGALE"
     gene            23901..24329
                     /locus_tag="VXE01_000673"
     CDS             23901..24329
                     /locus_tag="VXE01_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEV0749635.1"
                     /translation="MKLTLNIEPKPQSRPRFARRGSFTTTYEDKDMKTWRNHCQLLIA
                     NQYMGQPILEGALRARLRFYIKPPQYISKVKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEVEVMEWNA"
     gene            24373..24795
                     /locus_tag="VXE01_000674"
     CDS             24373..24795
                     /locus_tag="VXE01_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749636.1"
                     /translation="MTKTIELPDYYEPDWGNARYGTLEELKELLLYKRIVEWDKDFLL
                     LEDGTKVTIEMSESDCCASAGGEFQNVSLDAVITNVEIGEQEEIPDHWGAGYKNKVTI
                     FHNQNPVAIANCEAEHNGYYYSVGSLVIGDIHFPVVHA"
     gene            24840..25169
                     /locus_tag="VXE01_000675"
     CDS             24840..25169
                     /locus_tag="VXE01_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749637.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMSQLVIAVYLIY
                     RGSEDET"
     gene            25159..25830
                     /locus_tag="VXE01_000676"
     CDS             25159..25830
                     /locus_tag="VXE01_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0749638.1"
                     /translation="MKLNELIKKYKKLEGVWNAEGAELARQIFLQDLEQLDESEIGYA
                     DEAPRYVKNILARLRELPLHDREVWLKAIMSEFEQDFSRAKWREGYEQGKIEGMVERE
                     KVKVPRFVAEWIEEARKACKDVVELFEFDFTNDEVRKWFMQERPFDLVARAWLDGYEV
                     EEEKRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEEAGLGWVFDCEGVE
                     IEEVE"
     gene            25943..26392
                     /locus_tag="VXE01_000677"
     CDS             25943..26392
                     /locus_tag="VXE01_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749639.1"
                     /translation="MPNFAEGTIKLRGHAENIKSALKYMFEAAGDVTIEEDTDGELII
                     FTSSNSYFYINGTKRAFIDGESFEIHLDDDFLIIELNNFTQAWRAIPDNYIEISEKFN
                     VDIKIFTFEQGLEFTQEIEISKGKILKDIVLKYGDYRWEVAFSNLGG"
     gene            26411..26821
                     /locus_tag="VXE01_000678"
     CDS             26411..26821
                     /locus_tag="VXE01_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749640.1"
                     /translation="MIPKFRGLSIDEKSKGEWQYGHLIEDRGRAFIISEVVEANEQYI
                     TIGSWCPVNPATLGQSTGLRDKNGKEVFVGDIIKCTRGCLHEVYIEKEYGGTYFGGMP
                     AVYLKDLREGYAWTEHEEIIGNIYENPELLEVNE"
     gene            26896..27138
                     /locus_tag="VXE01_000679"
     CDS             26896..27138
                     /locus_tag="VXE01_000679"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0749641.1"
                     /translation="MVDKYIDEPHTTFIPVINGKSSVLVPTRTKRKYILVISGYAGNK
                     QVEERFEVTANEYKHYEIGNTFIQDAVLENKEEDKE"
     gene            27135..27500
                     /locus_tag="VXE01_000680"
     CDS             27135..27500
                     /locus_tag="VXE01_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749642.1"
                     /translation="MKPKKYPYSGKMQKIPSPIFSARPIFNEVPIVEEVKVEFGVEAS
                     MGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRFLT
                     FRESDWKFFIRDLVNEFKH"
     gene            27573..27977
                     /locus_tag="VXE01_000681"
     CDS             27573..27977
                     /locus_tag="VXE01_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0749643.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            28058..28140
                     /locus_tag="VXE01_000682"
     tRNA            28058..28140
                     /locus_tag="VXE01_000682"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28089..28091,aa:Tyr,seq:gta)
     gene            28445..28885
                     /locus_tag="VXE01_000683"
     CDS             28445..28885
                     /locus_tag="VXE01_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV0749644.1"
                     /translation="MSGLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMRGETQEQTLISIGELGQTITD
                     IDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            28863..30161
                     /locus_tag="VXE01_000684"
     CDS             28863..30161
                     /locus_tag="VXE01_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV0749645.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRNLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYQTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAELRL
                     IEELRSEHGITRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQQDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            30173..31642
                     /locus_tag="VXE01_000685"
     CDS             30173..31642
                     /locus_tag="VXE01_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0749646.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHSTESSHLKKLKSYYL
                     GEHAILEHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMAELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKYQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            31551..33188
                     /locus_tag="VXE01_000686"
     CDS             31551..33188
                     /locus_tag="VXE01_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEV0749647.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVDARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPESEIKHLQSFSWVGDGSTYSTNIWKNTGKLTSSIKDELLISLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKVEYVPADM
                     TYKEWYSKYVAKDGEKVYNQDTREANAKFYSEQLLSKISGVEPKITSDMQRIAGENKL
                     AGLEFRKKTVESLSRKIIADSLVENISLSKAVSKINDALRYTTIFDSDTFTEEYLKMK
                     QKLIAEGYKIVKVKNTWLVDGPYKGVNTVVEKDGINFEMQYHTQESFDLKNGSLHELY
                     EKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            33190..33399
                     /locus_tag="VXE01_000687"
     CDS             33190..33399
                     /locus_tag="VXE01_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749648.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSMDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            33396..33809
                     /locus_tag="VXE01_000688"
     CDS             33396..33809
                     /locus_tag="VXE01_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0749649.1"
                     /translation="MIDIALAIAKKAHAGQVDKAGVDYIQHPLYVASQVNTEQEKAVA
                     LLHDVIEDSDITAADLLASGLSNEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIYYLST"
     gene            33852..34139
                     /locus_tag="VXE01_000689"
     CDS             33852..34139
                     /locus_tag="VXE01_000689"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749650.1"
                     /translation="MNKYKKLIELIENNGLEIQSKKCYDPQSAWHGEELWIVDKKKQN
                     KIFDLSGNGYCFHDAKVEEAIEEVEKYLLLKKMDTFDDFKKWVEKNAKPKK"
     gene            34280..34492
                     /locus_tag="VXE01_000690"
     CDS             34280..34492
                     /locus_tag="VXE01_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749651.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDL
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            34662..35186
                     /locus_tag="VXE01_000691"
     CDS             34662..35186
                     /locus_tag="VXE01_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV0749652.1"
                     /translation="MSEEINATVSTESTETVDTQENVDTVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLEQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTNAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQT
                     VQQEVTEKWRKDFL"
     gene            35209..36234
                     /locus_tag="VXE01_000692"
     CDS             35209..36234
                     /locus_tag="VXE01_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HEV0749653.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFGAALGNVSDNVAMGNTAGANNAYNAVLDVSEKLDEL
                     GITKERLLFVTPSFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKKSVQGKVVNRAKAWKTGTTYKEGESVTHADKVYVAVKDISNSATAPDTDTTNW
                     KEKTGKK"
     gene            36244..36432
                     /locus_tag="VXE01_000693"
     CDS             36244..36432
                     /locus_tag="VXE01_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749654.1"
                     /translation="MKFKIKQDFYDWESNVKRLVGEELEITEERYAELADNIASNGVT
                     ISDVLEKILPEPEFLEED"
     gene            36434..36745
                     /locus_tag="VXE01_000694"
     CDS             36434..36745
                     /locus_tag="VXE01_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV0749655.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATSLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            36726..37064
                     /locus_tag="VXE01_000695"
     CDS             36726..37064
                     /locus_tag="VXE01_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749656.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            37039..37554
                     /locus_tag="VXE01_000696"
     CDS             37039..37554
                     /locus_tag="VXE01_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV0749657.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNAAIKVVQADAR
                     RLVPVNDGELITSIKTRAKMDGDRAIGEVYTNLKYAPYVEFGTGPKGQASHSGISPEV
                     SVTYKSHPWYVHEDQINVGSYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIQ"
     gene            37551..37919
                     /locus_tag="VXE01_000697"
     CDS             37551..37919
                     /locus_tag="VXE01_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749658.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDKEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            37922..38335
                     /locus_tag="VXE01_000698"
     CDS             37922..38335
                     /locus_tag="VXE01_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0749659.1"
                     /translation="MLANGIKLAFSETKGNYQNLVGLKEVPEFGIEPEKVENTTLADT
                     VKKYEFGIGDAGELEYKFAYNNSSATAPYRVLRKAADGKKKLYFEQTYPDGTKVTFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSNLTFTDGVGG"
     gene            38340..38720
                     /locus_tag="VXE01_000699"
     CDS             38340..38720
                     /locus_tag="VXE01_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749660.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKGKKTSKKKMTVVE"
     gene            38759..39109
                     /locus_tag="VXE01_000700"
     CDS             38759..39109
                     /locus_tag="VXE01_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749661.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYI
                     LSRMITNHVSLLLSNDAKIVELWEYAPELFVEEQQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEVNGNS"
     gene            39096..42749
                     /locus_tag="VXE01_000701"
     CDS             39096..42749
                     /locus_tag="VXE01_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749662.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKRFSNGQSWDQLDFQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERIIRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKTSSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDMFQKAWTGLTNIFSKLGSWFGERWNDVTSALSKVASWFGD
                     IFGKAFDAVKNAFSSIGDFFKGVWDTVKSIFVNAGQMVGEAVGGAFKSAVNAVLGTIE
                     NVVNGFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGVSPQSGFSGDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
     gene            42758..43108
                     /locus_tag="VXE01_000702"
     CDS             42758..43108
                     /locus_tag="VXE01_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749663.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSKFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            43113..>45697
                     /locus_tag="VXE01_000703"
     CDS             43113..>45697
                     /locus_tag="VXE01_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0749664.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGDYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQVIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGIEAKIQAQIEAADAAFDAEFDKREKAITDAIELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELDGASTLLAQE
                     AKRIELDSVARLEAFKSQTTSAQTALSGDLDALKRTIANDIRQKQAQAETEIAKQVEA
                     LSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASKIASVHL
                     GRRNLLKGTKELARYKPVSEYNGFKVIRTVAGATRYQDSYVERTVIPTAGTEYIAIFY
                     ARASENDYPVRCHFYNPNTVVSSENSSGYKSRSSDGLSIIRLSTDWQLCWVKWTQTAT
                     DQAKTVIIGRHGPQVGGKEGVWVEICAPAIFEGNLAGDWSPAYEDQDERVSAVESNFK
                     QRADSLEAGVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFE
                     VRAGS"
BASE COUNT        14418 a         8082 c        10535 g        12662 t
ORIGIN      
        1 tgatttcgat aggttgttga aaacatttta aacatttcta ctttggcaaa gatgttctca
       61 accttgcttc tctccttaga tagcgcatgg ttataggctt tatcttcaac tgttagcggc
      121 ttgagtttgc tggatttacg tggagtttgt gcttgaggat atatcttcat gagcccttga
      181 taaccactgt cagccaagat tttaccagct tgtccgactt ttttgataag ctgtttttaa
      241 tacagctaac atctcttcaa aagtggtacg ctgaacacta acaagacgct taaatcgtgc
      301 atcagttagt tgtttacttg cttcataatt catagaacta ctataccata ttttgtttcg
      361 caggaagtct aataagttat agtccagttt ttactatact ttgatattca aatatgttat
      421 actatggtta tcaaagtaaa tgaaaggagt tacgaatatg acgccagaag aaatgtacct
      481 gacagagcga ttagacgtac agatagctca ttttttaaag aaaagcgttc aacatcgtag
      541 acgctataag gtattaaaaa taacagaaat cgtggcaggt ttcctcatag ctgtcttttg
      601 tgctattcct atgccaggtg atcgctaccg tttgatttcg gttgccttat ccagtctcgg
      661 cttgctgtgt gaggggatta tcaatttgta taatgcaaag gaaaattgga tttcttacca
      721 aaaaactgcg caactcctgg agaaagaaaa attcctctat caatgccaaa cggagaaata
      781 tgcaggaaag accaaggctt ttgccctatt tgtcaagaca tgcgaaggtc ttatctcaga
      841 ggagattaac cagtgggaaa gtatccagtc aaaagaagtg gcagctagtg cagatgctcc
      901 agttaaaaaa gagtaggagg tagaggaaat gtctcaatcc agctacctgt cgcccttgct
      961 ctggttaaaa aaagaagccg ataaggaaaa gatgagcgcg acccagtgcc agatattttt
     1021 cttttactat caaatgtttg agctcttatt tgctagagaa agcgacatga aagacttatg
     1081 tctgggaacg aaaggttttt atttctcgca gttagagaaa aatttgcttt ctggagtttc
     1141 ccgatttcta aaaaacttgg aggggaaagt aactctcaag gctaaccaag aagtatcagc
     1201 tcgcaaagcc ctttttctag ccttgacaac tagccaatca gattggcagg agttagctcc
     1261 tgtttttgat ttttatcaga ctatcgggag gcttgaaaat ccttctcgct tgagttctca
     1321 ggacagacaa catctgatgt ggatttacca gtcagctttg gagaaggatt atattgtcaa
     1381 ggttattggc gacaagcatt ttgtattgaa gagacaagat gctactaaat tgacagcgcg
     1441 ccaaactcaa actttggaaa ttctgagtca atcagaagac ttggtcaatc ctgtctatgt
     1501 tacattagga gaaaaggggg tgctcttgct tgattaagag aggagatgtt gtagctcttt
     1561 atttgccttt tccgactatt agtagcgatt tggctgtgaa gaatcatatg tatatctgta
     1621 ttgacaacag catgactaaa aacaaagagt tggttaaaaa tcagaccttc aaaccagctc
     1681 tcttgaccag acgtttggtc aagaacttta tgatagaaga gccggatcta gctcgtaatc
     1741 cttttacaag accaaccttg attgacttag ataaggtatt tatgttggat aatacggtta
     1801 ttccgacttc ttatctagcc agacggcgac gcaatgtctc agaagaattg tacgaggaaa
     1861 ttttggatta cttagtccaa ccacggctga tttcgctgaa caagtctgag tttatgcaac
     1921 tcaatccagg aacttattag gaggtagaag atggcaaata aagcagtaaa tgactttata
     1981 ctagctatga attacgataa aaagaaactc ttgacccatc agggagaaag tattgaaaat
     2041 cgtttcatca aagagggtaa tcagctaccc gatgagtttg ttgttatcga aagaaagaag
     2101 cggagcttgt cgacaaatac aagtgatatt tctgtaacag ctaccaacga cagtcgcctc
     2161 tatcctggag cacttctcgt agtggatgag accttgttag agaataatcc cactcttctt
     2221 gcggtcgatc gtgctccgat gacttatagt attgatttgc ctggtttggc aagtagcgat
     2281 agctttctcc aagtggaaga ccccagcaat tcaagtgttc gcggagcggt aaacgatttg
     2341 ttggctaagt ggcatcaaga ttatggtcag gtcaataatg tcccagctag aatgcagtat
     2401 gaaaaaatca cggctcacag catggaacaa ctcaaggtca agtttggttc tgactttgaa
     2461 aagacaggga attctcttga tattgatttt aactctgtcc attcaggcga aaagcagatt
     2521 cagattgtta attttaagca gatttattat acagtcagcg tagatgctgt taaaaatcca
     2581 ggagatgtgt ttcaagatac tgtaacggta gaggatttaa aacagagagg aatttctgca
     2641 gagcgtcctt tggtctatat ttcgagtgtt gcttatgggc gccaagtcta tctcaagttg
     2701 gaaaccacga gtaagagtga tgaagtagag gctgcttttg aagctttgat aaaaggagtc
     2761 aaggtagctc ctcagacaga gtggaagcag attttggaca atacagaagt gaaggcggtt
     2821 attttagggg gcgacccaag ttcgggtgcc cgagttgtaa caggcaaggt ggatatggta
     2881 gaggacttga ttcaagaagg cagtcgcttt acagcagatc atccaggctt gccgatttcc
     2941 tatacaactt cttttttacg tgacaatgta gttgcgacct ttcaaaatag tacagactat
     3001 gttgagacta aggttacagc ttacagaaac ggagatttac tgctggatca tagtggtgcc
     3061 tatgttgccc aatattatat tacttggaat gaattatcct atgatcatca aggtaaggaa
     3121 gtcttgactc ctaaggcttg ggacagaaat gggcaggatt taacggctca ctttaccact
     3181 agtattcctt taaaagggaa tgttcgtaat ctctctgtca aaattagaga gtgtactggg
     3241 cttgcctggg aatggtggcg tacggtttat gaaaaaaccg atttgccact agtgcgtaag
     3301 cggacgattt ctatttgggg aacaactctc tatcctcagg tagaagataa ggtagaaaat
     3361 gactaggaga agagaatgct tgcgacaaaa agaggcgatg atctctctgc ggatatctga
     3421 aagtttatct cttgcctagc gatttccatt ggagtatgct cgtgatgtta aaatgagtct
     3481 atcaaacagg atgtgtaaaa aagtaaaaag ggtagccaat tccttgatat acaggggatt
     3541 gattatcctt tacttgtttt agatgattgg aaattcaaga atgacacgta tcggaaatat
     3601 tttgctgttt atatctaata cccatttatg gaaaaaatga aattaaatat gaacaaatca
     3661 attgctagca atggtttaga agtgccagtg tactagtcta acttctccat cttgggaaca
     3721 cgtaaattat actcttcgaa aatctcttca aaccaggtca gccctatccg caacttcaaa
     3781 acagtgtttt gagcactctg cggctagctt tctggtttgt tctttgattt ttattgagta
     3841 ttagaggttt gcttagaaac tcttctattg atttcttaga atacaatagc gcctataaga
     3901 actgttggat ttcaaagtat ttacttgaac tatgatatgt ctggagtaga ctgtcaacaa
     3961 aaggtgcagt atgattgttt ttgtcgctta tatctacaaa cttcaaacag taatttgagc
     4021 tgactttgtc aaacttggct gaaactttct atttgcagat aatggtctag tttgtttttt
     4081 gaatgtggat gagtgtctgt tgataaagat agaaaggcaa gaccgtctta gcaggtaaag
     4141 tgctatccta gcttgatttg ctaataaaat ccatttcctc tagtgaaaat caaaaaaact
     4201 tgtgttataa taagaaagat taaaatgtga aaaaaggaga ttcctaatgg gacgtaaatg
     4261 ggccaatatc gtagctaaga aaacggctaa agatggagcc aactctaaag tatatgcaaa
     4321 atttggtgta gaaatctatg tagcagctaa aaaaggtgat ccagatccag aatcaaactc
     4381 agctttgaaa ttcgttatcg accgtgctaa acaagcccaa gtgccaaaac acattatcga
     4441 taaagcgatt gataaagcca aaggaaacac agacgaaacc tttacagaag gacgttacga
     4501 aggttttggg ccaaatggct ctatgctaat tgtggatact ttgacttcta acgtcaaccg
     4561 tacagcagcc aatgtccgtg cagcctttgg taaaaacggc ggaaacatgg gcgcttcagg
     4621 ttctgtttct tacctttttg acaacaaagg tgttattgta tttggaggtg aagatgcgga
     4681 cgcagtcttt gagcaattgc tcgaagcgga tgtggatgtg gatgacgtag aagcacaaga
     4741 aggtacaatc acagtttaca cagcgccaac tgaccttcac aaggctatcg ttgctctccg
     4801 tgagtctggt attgaagaat tccaagtgac tgaattggaa atgattcctc agtcagaagt
     4861 ggaattgtca ggcgaagacc ttgaaacctt tgaaaaactt tacagcgttc ttgaagacga
     4921 cgaagacgtc caaaagattt atacgaacgt agatgggttt taatttaacc tatagaacat
     4981 gatcctaagt gagaaaatca cttgggattt ttttaatcaa gaaaatagtt ctcatagaaa
     5041 tttaattatt ctccagagaa ctatttttat ttagaagggg gagattatgg gtaaaccgat
     5101 gttagtcttt aagcgttttg gtcatcaaat tcacctgatg gtgcaaaagg aagccaaacg
     5161 ttgcggcatt gaatttatgg gtgggccgca aggtcaggtt gtgcattttt tggataatcg
     5221 cgagaaaaac caagacttgg tcttgattaa agatatcgat caggaactca atattaccaa
     5281 gtctgttgct agtaatctgg ttaagcgtat agtgcaaaat tgtttggtgg aattggaggc
     5341 gagtcctgtt gataagcggg ctaagtttgt tcgtctgacg gacaaagcac gttctcagat
     5401 gcaacaggtt aaggcttttt ttgaacgcat agacaagcag ttgatggaag atattgatga
     5461 agatgaatta ctgatttttg agaaggttct cggtcaacta caggcaaaat atcaagggaa
     5521 taggaggaga gaataaagaa attagccaaa agaattagta gaaaagaatg ggggatgatt
     5581 ttactagcca ttctctttac ttgcttttcg gtctatctag agttggaagt gccgacctat
     5641 atctcgaaaa ttacggattt gctaggtagt caagaaacta atttagatga gttgtggcag
     5701 ccggcaagca tgatgatggg aatgtccttt cttgccttct tgtccgtagt tgcagttgga
     5761 ttttttgcat cccgagtggc ggcttcttat actagtaggc tgagaagtga tatttttaac
     5821 cgagttttgg attactcgca gacagagatt aagaaatttt caattcctag cctcttgacg
     5881 cgtactacca atgacattac tcaagttcaa atgttgatta ctatgggctt gcaagtggta
     5941 acgcgtggtt caattatggc tatctgggct attgggaaga ttttaggtca ttcagaatac
     6001 tggctctggg ccgtacttgt ggtagtgatt gtcaacgtcc tgatgacgac cgttttgatg
     6061 acgctagcct ttccaaaaca gtccttgatt caggggttga cagataaact gaacagtatc
     6121 actcgtgaga gtttaacagg tattcgtgtc gttcgtgcct acaatgcaga ggattatcaa
     6181 aatgaaaaat ttgcagcagt aaatgatgaa ttgacccgtt tgaatttgtt tgtcaaccgt
     6241 cttatggcta ttttgaatcc tatcatgatg gggatttcaa gtggtttgag tgtagcgatt
     6301 tactggattg gggcctatgt gattaacgac gctgctccga tagcgcgtct gcctctcttt
     6361 agtgacatga ttgttttcat gtcttatgcc atgtaggttg tcatggactt ccttctcatg
     6421 ggagcactct tcatcgttct tccccgaact atggtctctg ctaagcggat taatcaagtt
     6481 ttagatttgc attcttctat ccaaaaccct gctcaagtgc agctgactga tgaaaacttc
     6541 aaaggtcagg tcgagtttaa ggatgtgacc ttccgctatg cggcaaattc ggaggcagtt
     6601 attgaacatg ttagctttaa agcagaaact ggtcaaacag tggcctttat tgggtcaata
     6661 ggttctggta aatcaactct ggtcaatctg attccacgtt tctacgacgt gtcagcagga
     6721 gaaattctgg tggacggtgt caatgttcaa gactatgact tctctgcgac agctcatgct
     6781 ggtcaaaggg ttgccattgt tgggccgact ggggctggta agacaaccat tgtcaatctt
     6841 ttgatgaaat tctatgagat tgataaggga agtattcgca ttgatggtgt ggataccaag
     6901 gctatgacgc gttcagaagt gcatgatgcc ttttcaatgg tcttgcagga tacctggctc
     6961 tttgaaggaa ctattcgaga caatctcatc tataatcaaa tagggattag tgatgaacga
     7021 atgatggaag ctagtaaggc tgtgggaatt caccacttta ttatgacctt gccagatggc
     7081 tatgatacca tcttggatga caccgtgacc ttgtctgtag gacaaaaaca actattgact
     7141 attgcttgtg cccttcttaa ggatgcatcg cttttgattt tggatgaggc gacttcttct
     7201 gttgacacac ggacagagga attgatccaa aaagccatgg accgtttgat ggaaggacgc
     7261 acatcctttg tcattgccca ccgcttgtca atcatccgaa atgcagactt gatcttggtc
     7321 atgaaagatg gaaatatcat cgagcaaggc aactatgagg aactgatggc gcaaggtggc
     7381 ttctacgctg acttgtacaa tagtcaattt acagaagatg aagcagaaga ataaatcaaa
     7441 aaaggcttga cggccttctt tttcttattt atactagtac acatagaaag agagaagtat
     7501 gagtcagaaa ttatacaata tgaaatttgc tgctgtctac ttagccttga ttgcaaaagt
     7561 tgagcgaaag ggtgaaaagg cagagtcagt tcaccaagtg accagttggt tgacagggta
     7621 tgaagtgagt gacgttcttg cttgtctgga tagggatgtt acttacggag atttttttct
     7681 acaagcacca tattatgtcc ctgaacgaat tacaattaca gggaagattt gcggtgtccg
     7741 tattgaggaa attgatgatc ctctgatgca ggaaatacgt cgcttggaca agctagtgga
     7801 ttggcttgcc aaggggaaaa catctcaaca agttctagaa aagtatgaga agcataaatg
     7861 aaaaattatc aagaatggta tcgaaatatc agctccagac taactagtcg tccaattctt
     7921 ttattcctat tacgcagttt caatcgtttg atgacagtcg ccatgcccct ggtctatctg
     7981 atcttgctag tcaccactta cctgcaacta ggacttggtc agcaagttgg ggtttatgtg
     8041 cttattcctg catcaggttt tgtggccttg tccctgtttc gtaagaaaat caatcacccg
     8101 agaccttatg aaacttggga tatctgtccc cttcttgata aggatagtgc gggacggtcg
     8161 atgcccagtc gccatgtctt ttctgcaact atcatctcca tggcctgtct gcatgctagt
     8221 ctacctattg gcttagtatg cttgatcttt tcagctttgc tggggttggt gagggtttta
     8281 gggggtgttc attatcccaa ggatgtcttg gttggctatg cttgtggtct ggtgtgggga
     8341 ttccttttct tcctattctg acatgtaagt taagctagtc ctacaaccac ttactgcttc
     8401 aaattgacca cttgcttttt tgcccttgta ttcctaactt agctttgata tagtagagtc
     8461 agaaaggaga tgtgatgaag ttacgaattg agattgacgg caatttagag gagactgaaa
     8521 ttgtcatcaa gacccccact ttgacagatg aaattgcaga cttgcaacgg ctcttgcaag
     8581 agtcaaaggc tccgaggttg actttttaca aggggacagg tgaatattat ctagacctgt
     8641 cagaaattct cttctttgaa acagaaggga gcaagatcta cgctcataac cagaaggaag
     8701 cttatgaggt tcgcctcaag ctctatgagt tggagtctat cttgcctcgc tattttaatc
     8761 gagtttccaa gtcaacgatc gcaaacatcc gtcagattta ctcagtggac aagtcctttt
     8821 caggaacggg caccatttcc ttttatcaga cgcacaagga ggttcatgtc tcacggcatt
     8881 accaatccct cctaaaagaa aatctaagaa acatgaggta ataagatgaa aaagaaagca
     8941 tttggtattg tgttacttgt actagcagct ttaatattag tacaaggaaa ttttggaatc
     9001 ccttctctag gagggcacat ttggcccttg attggtattg ctttttttgc ctaccaatca
     9061 gttggagctt tgttgcgtcg ccacttaact tcagcctctt ttacagctct agtagcctta
     9121 atgattgcta accactttta tggcatttta ccgattccaa accagacact aatctgggca
     9181 ggagttctaa tcgttctcgg agtaaatatg ttgactcatt ctaacagaac ttggaatggg
     9241 aaaaaatggt ggtatgatgg tgaaaaaaac attcttatag ataaggaagt tgcttttggg
     9301 acagggactt tctacaagca agaccaagaa ttggtagaag accaagtaga agttggtttt
     9361 ggcaatgcaa aaatctacta tgacaatgca gagatgttag gtgattttgc aactttaaat
     9421 attgaagtag cttttggtaa tgcaactgtc tatgttccgc aacactggcg tgtcgatttg
     9481 aaagtagaaa catcctttgg tacagccaag gcggacgctc ctgtagcgcc aacaagcaaa
     9541 accttgatta ttcgtggaga cgtggccttt gggaagttgg agcttgtcta cgttaaataa
     9601 aaaaatcttc acttaaacca tcaaaataga cgtactaaga gtaggaaatt gatgccttgc
     9661 tctgatttca gttctatggt tgttagactt taaaaaatga aatgttgcct ttaaaagttg
     9721 tatatttttc gatattttga ctcttacgtt tgatgtatct atgtcctaca gcgtggatga
     9781 tgtagtgtaa aatgctttaa aaaaaaaatg aatgatattg gacagttttt ttgaactttt
     9841 aattgctcag gagccatgaa agcaagcgct tgggtttatg acaagggaga atggtattat
     9901 gtaagttctt ctggttccat gattgcgaat gattgggtca aagacaatgg caagtagtat
     9961 tatctggctt catcaggtaa gatgcttcgc aatacctaca cacctgatag ttactacgtt
    10021 ggcaacttag gtgcctggca ataagaataa tactcttcga aaatctcttc aaaccacgtc
    10081 agcttcatcc acaacctcaa aacagtgttt tgagctgact tcgtcagttc tatctacaac
    10141 ctcaaagcag tgctttgagc agcctgcggc tagcttccta gtttggtctt tgattttcat
    10201 tgagtataag aagtcctttt ccttaaagga agaggctttt tacttgcttt tttgctgttt
    10261 cctcatttgt cctaaagcct tttttgtgtt aaaatgaatg gtatgaaagc taaaaaaatg
    10321 tggatggcag gtctggctct gcttggtatt gggagccttg cccttgctac gaaaaaagtt
    10381 gcagatgacc ataagctcat gaagactcag gaagagttga cagcgattgt acgagaccat
    10441 ttttcagaca tgggggaaat tgcgaccctc tatgttcaag tctatgaaag cagtctagag
    10501 agcttgcttg gtggcgttat ttttgaggat ggccgtcatt atacctttgt ctatgaaaat
    10561 gaagacctag tctatgagga ggaagtctta tgatacaacc agcaagttta gaagaattgg
    10621 catctttagt agaaaaagac ggtaagaagg tcttcctttt tgtggcggac tggtgtggcg
    10681 attgccgtta tatctatcct gccttaccag aaattgagga gagtaatcca gagtttacct
    10741 ttattcgagt ggatagagac cagtatatag atttggccaa actctgggat gtatatggaa
    10801 tccctagcct tgttgttcta gaaaaggaca aggaaatcgg tcgttttgtc aatcgcgacc
    10861 gtaaaagcaa gcaacaaatt aacgattttt tagcaggatt gaaataggag aaaaaggaaa
    10921 caatgatttt tacatataac aaagaacatg tcggtgatgt ccttatggtc atcgtgaaaa
    10981 atagcggaga tgctaaactg aatgtggaac gcaaagacaa ggtagcccgt gttttcctca
    11041 aagaaaatgg ggaaacagta gcttggaaca tttttgaggt ttcgagcttg tttgaaattg
    11101 cagagcgcgg tcaagtcttt ttatcagatg agcaagtcgc tcgtttgaac caagaattac
    11161 aggcggaagg ttttacagaa gaaattgtta atgataagga acctaagttt gttgttggtg
    11221 aaattgtcga gatggtagct catccagaca gtgaccacct caacatctgc caagttgcag
    11281 tcgcaagtga caagatagtg caaatcgttg caggagcacc taatgcgcgt gttgggttga
    11341 aaaccattgt ggctcttcct ggtgccatga tgccaaaagg gaatttcatt ttcccaggcg
    11401 aacttcgtgg tgaaaagagt tttgggatga tgtgtagtcc tcgtgaattg catttgccaa
    11461 atgctccgca aaaacgtggg gtgcttgaat tatcagaaga ccaagttgtc ggaacaccgt
    11521 tcgacccagc gaaacactgg actgcctagg aacttgtcag catctgatag aaggaaataa
    11581 gatggcaaaa aatgtagtga ttacgggagc aacctcagga atcggtgaag cgattgcgcg
    11641 tgcttatctg gagcagggtg aggatgtcgt tctaacagga cgacggatag acagattaga
    11701 aatcctcaag tcggagtttg cagtaagctt tccaaatcaa accgtctgga cttttccact
    11761 agatgtgacg gatatggtca tggtgaagac tgtttgctct gatattctag aaacgatagg
    11821 gaggattgat atcttggtca acaacgccgg actggctctt gacttggctc cctatcaaga
    11881 ctatgaggag ttggatatgt tgaccatgtt ggataccaat gttaaaggtc tgatggcggt
    11941 tactcgctgt ttcttgccag caatgataaa agtcaatcaa ggtcacgtta tcaatatggg
    12001 gtcaaccgca ggaatctacg cctatgctgg tgccgctgtt tactcagcta ccaaggcagc
    12061 ggttaagacc ttttcggatg gactgcgaat tgataccatc gcaacggata tcaaggtgac
    12121 aaccattcag cctgggattg tcgaaacaga tttctcaact gttcgttttc atggtgataa
    12181 agagcgggct gcgtccgttt accaaggaat agaagccttg caagctcagg atattgcaga
    12241 catagtagtc tatgtgacca gtcagcctcg ccgtgttcag attacagata tgaccattat
    12301 ggccaatcaa caggcgacag gtttcatgat tcataaaaaa taagaaattt cctcgaaaag
    12361 ttacaaattt ctgtaacttt ttttgatttc ctacgaatag ataagtagga ggaagaaaat
    12421 atgtataata aagttatcat aattactttg actaaaatac agaaatacgc tagacccttt
    12481 aaaaatctag cgttatcgac atgccgtctt ttgtaacaat aatttctttt atgatatttt
    12541 tgacaatttt tgaagcatct tcgtagctta atttttcaac atcgaagtcc tttagtagcc
    12601 gtgttagctt tctctttcgg atgctcagaa cattcgattt ttgattttcg agctgttctt
    12661 ccaggaattg cctttctgtt ttgattttat catttttctt gtccaactct ttccgagtga
    12721 tgatttcgtc caagtacaat tctgttaatt ttgagacttg attatttatc cgttcgagtt
    12781 gtttctttat ctcctcgacc ttgatagtct cttctttctt agcaagtgtc tcatttttat
    12841 attttggatc aaatttaatt ctttcaagtt ccttgattac aaccctttca agttcctctt
    12901 tagagtacca ccctgattcg catctttttt ctaaatcttt gctgtgtcgg ttcctgcatt
    12961 ggtatttatg atgagagatt ccattcttgt cttttcttgt atatctcaga ccaagtgaag
    13021 caccacaata tccgcatttc attaatccag aaagcatata ctttgccctg aacggccttg
    13081 gattgttata tttttcatag gctgaaatct gccttctttc gacttcaagc tggactaagt
    13141 caaacaattc ttgagtgata attggttcat gctgcccctc gtatacctta tctttgtact
    13201 ttacttttcc caaataggtt tcatttttca gcaagtattt cgtgattgtt tcgccccaag
    13261 gtctttttct tccaacgtga ccttcagcat ttaagtctct gatgatcttg actactggct
    13321 taccgttcaa gtattccgtg aaaatacggt tgacaatgag cgcttgggtc ggattcactg
    13381 ataagacgcc agtttctttt gagtaatcat agccgaatgg tattgtcgtc catgacatgg
    13441 attttccatt ctttgcccgt ccttcttttc ctaacatcat acgctcttta atctgctcac
    13501 gctccagctg agcgaatact gatagcatac cgattgaagc cttgccgaaa ggcgtagaag
    13561 tgtcaaagtt ttcttgcaag ctgataaatg ccacatcgtt tttagcaaac acatcttcaa
    13621 tcagaaacag agtatctttc tggctacgac tgaggcggtc tagcttgtag actagcacta
    13681 tatcgacttt cttgcgcttc acgtctgaga ttaaacgctc caattcaggt ctttgagtgt
    13741 tagcacctga gaaaccacca tcaacgtaga catcgtagat tttccagtct ttgattttac
    13801 agtaggcttc aagcttgtct ttctgctcat cgatagagta accctcttcc acctgcgaag
    13861 tagtggacac cctgacgtag attgcgactt tattcgttgt tttcattgaa tttgtacccc
    13921 ttttttgata aaataggtac aagaaaacgt ctcaaaaggt aatatctttt gaaaagtttt
    13981 tcttgccact agcctcacgc tcggagtcgc caaactttga gagcgtgagg cttttttgtt
    14041 tgcaattatt tccattttgg aaacagttgg ttttattctt tcgataagtg ttgttgaaga
    14101 attaaggcca cgttggcttt ctcttcctct gtcataggag gttcgtttgg atcgtctacc
    14161 gaaaactcga tagcatgcca tttatcattt actctaatcc actctcttcg tctgtggcat
    14221 ttgcaatcta ggttgtgttt aatcacttcc atcggtctac tttcgttact catgttattt
    14281 ctccctatac acactgacaa cttccccaat agttcggatg tcgttgcttt cgtctaggtg
    14341 tatatcctca taatctggat tcaagctttc cagatatccc tgacgcagtt tcttaacata
    14401 gttagcgccg tctacttgga agatgccgat agtgttataa tcaacctgtt gggtattctt
    14461 tataaaaaga tagtcaccat tctttatctt tggctccata gagttgccga cgacataagc
    14521 gatagcgtcg tagtcgtctg ggatttcatc ctcatagaac gaaacctcca tatctaaatc
    14581 gtcgtcctgt atcgaaccac taccagcaga gacaacccca gtaacacgtc ggtaagtagt
    14641 ctgtctgtag tcgtccagtc tgatgatgtt ctccgatact tcgtttatct tcgtttcttc
    14701 ttcgttttct tgactctcca gaagctcctc agatgtccgt agcacgattt ttttattgtc
    14761 agtatttaat tttcgagctg tatttgtaat ttcttctaaa agggagtctg acggttgtgc
    14821 ggtaaaaatc ttgttttcga taaggtcaga tttatttata ttaaaatagt ttgccaaaag
    14881 ttcaatttta ccaatacgag gataagttat tcctttcagc cagtcgcgaa ctgtagtgta
    14941 ttttaaatcc aagtctgcac ataatgtatt tctgtctacc cctttttgct ccatgtaaaa
    15001 acttagatta ttggcaaaaa tttctttatt ttcgactttc atttccgccc ctccttatat
    15061 agtatatttt acggcaaaaa cgcaaaaaag taaagaataa aataaaaaat tgcgaaaaaa
    15121 acgcaaaaaa cacttgacat tgcggttaaa ccgcagtata atataatcaa gcttaaggaa
    15181 ataacaaaaa caaaccggag ggaaacacca tgaacacatt aaacgagaaa gcaatcaaca
    15241 tctttaaagc agtagctaag gaaactttaa tccaaggcac ttacgaggaa aacttcctct
    15301 acagccaact tgaaacattc agtactaact gccgtcaatt cgctttcgga tggacagagt
    15361 tagcagatga gattgaacgc caagagcgtt accttctcga ttctggtttc actcaagagg
    15421 aaattgatga cattcgcttt gatgcagcgt tcgcaggaat gcaggacaaa atgaatgtag
    15481 cctgatcggt agtaccaggg ttcgactccc tggcaggctg ttgctcatag agcaaaaaaa
    15541 tagggaaagg aggtaggaaa tgaaagaatt gaaacaaatt tcagttaaga cttctggaca
    15601 cgatgtgtta ctgacggcaa gaaaaaacca ccctgctgta ttcgtcgatg ggatgtttct
    15661 cgacggagtt gagcgagtgg aatttatcaa taactttaaa gacaaagatt gtgaagtcat
    15721 tctttcgttc aatgaacgag tagaaaacaa tcctttccct ttaaatgagg tcagtctatt
    15781 agaaaagtta tttggtcagg cttcaaacgg gcaatcctta cgggatattg tcttgcaaac
    15841 tcttgaagat ggtaattagt atctaagcca tcaaaaaaag aaacatgaac actaaaactt
    15901 tcttttccgt ttttcttggt tctatcaaat tctttgccaa ggacgattaa agaagtttct
    15961 agctggtgat cagtcataac attacctcct ttctgactac attatagcag aattgcgagg
    16021 aacaaataga aaaataagga ggtaggaacg tgtcgaaaat gacattaaaa acactaagaa
    16081 cactcaaaaa ctggagacaa agtgatgcgg cagcagctgt gaatgtatca gttgatacat
    16141 gggggcattg ggaacgtggg ataacagagc ctagtgtttc gaaagcatat caaatcgcta
    16201 gtgttttcga tgtatcagta gatgatatta tttttttacc tgatattgcg gtttaaccgt
    16261 aacaaaaaaa tagaaatggg gaagaatgat tgaaaataag tggagagaaa ggggattaaa
    16321 tatgaggtat gcagtatata atcaggaata ctcatgggaa ttacacatct ttgaataatg
    16381 cttatgctca agacaaacgt ttaaaggcaa caacgatagg tatccttaca gtaatcttga
    16441 tgaataagtc tgattgggtt gtgtatcctg acgagattgc acgacgtcta ggaataagca
    16501 ggcgcaccgt agatgagcac tttaagcttt tagagaaagc aggctatctc agagtatatc
    16561 gcttagggtt aggcagaggt aaaggcgtaa cggtatatag atttttttca gatatgccta
    16621 tttcagatga ttactttgag tatctaaaaa ctaatcttga gaaagagtta tccacagata
    16681 acggagttta aaaatacagt tggaaaatat tgccatgtgt aaaattgcca tgtgtaaaat
    16741 tgccatgtgt aaaattgcca tgtgtaaaat tgccatgtgt aaaattgcca tgtgtaaaat
    16801 tgccctctaa taagtactaa ctatacaaca agtactaact atacaataat ctaagcctaa
    16861 cggcactaac ttagtaataa ctactaactt acaacaaact aatacttctc taaaaaataa
    16921 aagagagaaa tttcaatttt aggactttga aaaataggaa aggagaaaaa atgagaccaa
    16981 gaaaatatcc gtatagtttc aaaccaaatc tgatgaacat tttagatagt cgtttctata
    17041 cacggctaat tgttgaaaca gaggatggag cgaaaaaaat agcagaagtc acactagatg
    17101 atgtaacttc tgctacaggg tatgttgtaa ggctaagacc gaattatgac tagcctttag
    17161 gagggaatgg gtctttaccg tggctgtcac ggctttgaat tttcccatct ttgccatgaa
    17221 tgattagttc ggaatcttga tttcgtgaaa tctgtctagc aatattttta gcttcattct
    17281 ttgtagtagt atgaacagtt gctcttgaat tgccagcacc tttcacgttc caaccaccat
    17341 ttttggcagg gacaacatgc tgatttttgc ccatgattaa atctcctttc tattggaatt
    17401 ttgactaaaa cggtgagagg tcctagtcaa gagtattata gcaatttagg aggatattac
    17461 atcagtcttg aggctgatat aggaggttga atggaagata aaattatcga acttgctgac
    17521 tacttcatca gcgaatctac aacgtacaga gaagctaaaa tagcgtgtga gaagctattg
    17581 aaacaagtca gccatgagat agaactcagg gcaatggaaa gtaagacagt ctagaagaca
    17641 acaaaaagca cctgacggca atcaggcgca tactaaaaaa ctttacaaga ggattataac
    17701 atgaatatga acttaaatac aaatgaaatt ttaacaacta ctgaatatga tatgtttcgc
    17761 aaaattagta atagaaaaat aactgaaaat cctaaattgg aagaggagct actttctgag
    17821 ggacaacgtc agccgatttt ggtaaatgaa aaaatggaag ttatcgatgg gcaacatcgt
    17881 ctttattact tgagaaaaca tagaaaacca gtgcgctaca taattgatcc gaccgctaat
    17941 ttcaagacag taatttcgat gaatacatca gctgtcaact gggcattaca agattatgtg
    18001 tattcgttcg ctttagaggg agatcctgaa tttgttaaat tagctaaatt tttagacgag
    18061 aacgaattgc ttagtgacaa gatggtaatc gtagctggtt caggaagacg tgatggtacg
    18121 gcagcacacg tagtcaaaaa attaaaaaaa ggcgattatg tattttcaaa cgaaaaacag
    18181 ttaagagaat tttgtaagtt ctacgaacgc gttttaaacg aaacaaaact gcctaacaaa
    18241 ccatttttac aatctgtttt atggactttg tatacaacat cagtttttga tgaaaacaga
    18301 atgttgacac aattgaagaa atcagatttg acatcagaag atatcgaagg atttgcaaag
    18361 aaaaaattgc tattaacttt tttagagcta tacaacggaa gatggagtga cgatcatcct
    18421 tctttaattc aatactttat caacagaaaa gggtcgttaa caattcctag tttgcctaaa
    18481 caagatgaag ataattaaaa aagtaggaag ataaaatgaa agtcacagta tatgtttacg
    18541 gccgaaaatt agaaccagat gaaccaatta tcatcccaga aaatcatcgt ttttatgaca
    18601 tttggaacgg aattgtaaat gaaatgctcg acaacgagga ggatgtagct taatgaaact
    18661 acttactaaa ttaaaactca gactcgaagg agttcttaaa tcagtcaacc ttgactggaa
    18721 agaggtagca gtcgaactta tgaacgacct atttgaggag cgcaagcgtc gctttgcttt
    18781 cgagcaagaa aactatgact tgaagcagga gcttgctgcc tacaagtaca aagaaaactt
    18841 tgatatcaag gctagactgc aaggagaaat gtagatgtac attatatcga tttatgtcaa
    18901 gaatactgaa actggaaacg aggatttcag tttgattgga cgtgatttct taccgacggg
    18961 gcaccaagac tatattgcaa gagtttttgg aacaaaagaa gaagcgattg attacttaaa
    19021 atctatatct tacatcgcat caggtgttca tggtaacgat tgggtttatc aaaatgaaaa
    19081 actaccagaa attgagtcac gttgccgaat ttggaaagta ggagaataaa aggagaacaa
    19141 tatgtttaaa gcactaaaaa caatcaaaaa aatcaaacaa cttcagaaag aaatgcacgc
    19201 tttcagcctt gcgtttctag ctctacaaga tatgggcttg atgccagaaa ctgaaagaag
    19261 taaggcaaag gctcaaacaa tgcacgatgt aagccgcgta ctcaaggacg tcttggacgg
    19321 caagtcggta gatgaagcga taaagcgtct aaatagcgaa gtgaaagctg aagaggtggg
    19381 gcagaaagat gaccagaatt gaacttgaaa accgtgtatg gcttttggct aatcatgaag
    19441 aaaaaaacga attgctggat cttgggctaa cgtcaaagac cagatatgtg aagcgagttc
    19501 tggaactagg aaaggtgtat gctcatgttt gattatgaca gagatataat gcaaccgcct
    19561 gaagaacgag aagaacgtga cccagctgat tggattttca gcgctggtca atggatctat
    19621 gtaggagatt gttagcctat gaatagagag catttagagc gtgaaaattg gaatttgaag
    19681 aagacgaaag gtagaaagaa atgaaaaaac gattatatta caaaaaatgg aaacaagaac
    19741 ttagagaggc aatgagagaa gaaattgatg gcgattatct aaccgagaaa atggttagaa
    19801 aaatgagtat tagcgatatg tcacactatt tgaaccgatt agcattagaa gaagctggat
    19861 actgtgggac aatgtttaat tactaaaaga aaaagagaag aaaatgacta ataatcaatt
    19921 agcaacacag acaaaacgta acatcactac tgacccaagt ttattgaccg gggcagacat
    19981 caaaaagtat tttgacccac aaaacctact gactgaaaaa caagtaggtc aggcgctagc
    20041 cttgtgtaaa ggtcgcaatc ttaacccatt tgctaacgag gtctacattg tagcttacac
    20101 aaaccgtaat gggggcaaag agtttagctt aattgtctct aaagaggctt tcttgaaacg
    20161 tgccgcccaa tgtaaagact atgagggctt tgaggctgga gtagtggtag tagacagtga
    20221 gggtgttatg cacgaacgca aaggggcaat catgctccca gaagatacac tgataggcgg
    20281 atgggctaga gtgcaccgca aaaatttcaa ggtacctgtg gaaatttttg tcagtcgtga
    20341 ggaatatgac aagaaacaaa gtacatggaa caccatgcca gctaccatga tcaggaaagt
    20401 ggctctagta aatgctctta gagaggcttt ccctgaggac ttggggaaca tgtacacaga
    20461 ggacgacggt ggagagacat ttgaccgtat caaagacgtc acacctcaag agagccgtga
    20521 ggatgtcgta gcacgcaaga tggctgaaat tgagcaattc aacaaagagc aagaggcaaa
    20581 tcatgcagat cctgaaccta ctcaaaatga ggatccaatc cagggcgagt tgctagacgg
    20641 tgaacttgaa tattaggagg acaacatgca agaattacag gtaaaagtaa cacaagcaca
    20701 ggttgaaatc attgaccgtg agaaatttga gcagaatatc aatgaggttg cagcaaagta
    20761 tcaaaattac acggttacgg ctgcaactat caaggatgac aagcagacac ttgccgatct
    20821 acgaaaatta gacaagcagg tttctgatga acggatcagg aataagaaag tcttatctga
    20881 accagctgat gaatttgaca agtatgtcaa gaatgccatc cagcctctaa aagacatcat
    20941 taccaaaatt gctggtgatg tcaaagagtt tgaagaacat caaaaggctg tccgaattga
    21001 cacagtcaaa ggctacctag ccaacaaatc agctgagtac atgctggatc ctcgtctctt
    21061 tgatgaaaag gcccttgagt atgtcaaagc tagcgatttt atggcagatg gcgtgacgct
    21121 taaaaaagcc actatgaagt cacttgatga catggtcaca tttgaatttc agaaacaaca
    21181 agaatttgaa aaagccaagt cagctatttc agggttatgt gctgagtatg gcatgactga
    21241 ctcaccttac attagacagc tgaaagactt gactcttgct gaagtctttg gacaaatcaa
    21301 agctgattat gagtttgaaa agcaaaagga agaaatcaga caggctcaag aacgagcaga
    21361 gcgagaaagt caggaacttt tagcagccca acaaaccaaa cagcaagaac aggctccaaa
    21421 atcaacggaa accccaaatt ttgacccaga aacgggcaaa atcttggacg gtgagcaaat
    21481 ccctcaaaat gagcagaact ctcttagagg ggctgaaaat gacctaaaac gatataccca
    21541 aaaaatgact ttagaggtgt attttgtaga cacagccgaa aaagaccgtt tcaaggctgg
    21601 tctaagtcaa ctcggatttg attttaaaaa gaactatcaa gtcagcggtt atcaacgtat
    21661 tgagccattg actcaggctg aactcaatga gcaatgggga ggtaaccatg gacatcagaa
    21721 aaatatctga cagcgtagcc atctactcgg acggcaagaa attgcatgtt atccacaacc
    21781 taggggatga gtttatccta gattttaagg tgggagagga tagcgtctgg aacctcaatg
    21841 gccaagtcgt agaaattatt gacatgattg agcctgtctt taaagttttc agcttttgct
    21901 caaaatctgg agagggtatg caacgcttaa aacatgctat cgtccacttt gaaaaatttg
    21961 agcagtacat cagagataat caggaagacc tgatgatctg gtggcacaat ccaggagggg
    22021 aatatgatta aaaccgtatt tttttcatgt gattatccac atcatgaggc gattgacgac
    22081 caaataaata gctggcttgc cgaaaatcca ggcattaagt tgattgacat caaatttcaa
    22141 tcaaatgtgt ctgctgtcgc tgacagtgga gtcagtgctg aatattggca tacatccgca
    22201 ttgattattt acaaagttcc ctcagagaac aatataagca gtattaattc aaatggttta
    22261 ggtttcataa tcagctgtga gaaatgtggt agcttatcaa taatcaaggg aaaagatgta
    22321 ggtcaaaatg tatgttatga atgcaaagga gagaaataat gaatgatttt atcaaagaga
    22381 ttgggatggc tatcctatgg atgtttttag ggtatctctt gggagagcgt agcactagag
    22441 ggggacaaat cagatgatca ataacgtcac actggttggg aggcttgtag cgcctcctga
    22501 tctacgaaaa acgcctaata atgtatctag tttacagggc acgcttgcag tcaatcgcaa
    22561 tttcaaaaac gaaaatggag agcgtgaggc tgattttatc aattttcaag cttggagagg
    22621 tacagctgac atcattgctc agtattgcag caagggctca cttattggga tcattgggcg
    22681 cttacaagtt aggtcttacg agaaagacgg tcagcgtcga tatgtgactg aagtaatcgc
    22741 tgagagtgta gctctgctag agagtcgcaa cagtcagcac ggacaaggca acagtttcca
    22801 aaatgggaat agctcacctt ttaccgatcc taaccccttt gacctcccaa atgacggttt
    22861 gccgttttag gaggtatata tgtcaaaaat taaaattctt gacgcttgct gtggcagtcg
    22921 tatgttttgg tttgataaaa acgaaagtca cacaattttt atggacatta ggcaagaaac
    22981 atttgagata catgacaaaa aggtcaatgt agaccctgat attatcggtg attttcgtga
    23041 catgcctttt gaagacaaca catttaatct agttgtgttt gatccaccac atctaaaatg
    23101 ggctggacct aattcgataa tgaaagctca gtatggacag ctggacaaag ttacctggtc
    23161 ggaagatttg gccaagggtt ttgaagaatg tctgagagtt ctaaaagttg gcggcacact
    23221 agtctttaaa tggtctgacc gtcagataaa tgtaaagaaa ttactagagg tgataccatt
    23281 caagccctta tttggtcagc aaagaggcac cacacactgg ctaacgtttg taaagtttga
    23341 ggaggacaag aatggagtgg acggattggg tggattggaa acctgaaacc aaaacggaca
    23401 ttaaaaccaa aattgaaaat gacgggtaca cttttccaca ctatgacaag aaaaacaacg
    23461 gcgtcaagta cgtcatctct acactggaca tcaaacgaga ctgtctaaga cttggagtac
    23521 cgtttgaaga tgtgtaccct ttgcaaacga cactttttta acaggagaaa gaacatggca
    23581 agtaaaatca atgcgacaga acgtattgct atcatcattg agaaacaaaa aatagaggtc
    23641 gttacgactc taaactatga tatgagcatt agctttgata acaaagacac ggctcctaca
    23701 ctagatgaca atggtgacct ttttgaaccg gtctacaagt gcaaagttaa ggcaattccc
    23761 aaaaatgatg tatttttcac ctcattaaca cgggtcaaga gcaacatcaa gacgctacaa
    23821 gaggttaaaa aattctttga gttcgtaaac gaaaacagag aaaatctctt tgagatggca
    23881 ggatttaagg gggctcttga atgaaattga ccctgaacat tgagcctaaa cctcaatcac
    23941 ggccaaggtt tgcaagacgt gggagtttta ccacaactta cgaagacaag gatatgaaaa
    24001 catggcgcaa tcattgccag ctgctcattg ctaatcagta catgggtcag cctatccttg
    24061 agggagcttt gagggcacgg cttagatttt atatcaaacc tcctcagtac atttccaagg
    24121 tcaagaagaa ccagcaggcc ctcctagatg aaatcatccc agtaggcaaa aagcctgaca
    24181 ttgacaacta cgaaaaagcc ctatatgaca gtatgtcagg gatcgtattc caagacgacg
    24241 gtcagatagc tctgcatgat gtaggcaagt tctacagctt aaaccctcgc atagaggtag
    24301 aggtggaggt catggaatgg aacgcatgag gcgagattat gactgagtat ttgaagaaat
    24361 gaggaaatta agatgacaaa aactatcgaa ctaccagact attatgaacc cgattgggga
    24421 aatgcaagat acggaacatt agaagaacta aaagagctgt tgctctataa gcgtatcgtg
    24481 gaatgggata aagatttttt actacttgaa gatgggacaa aagtcactat tgaaatgtct
    24541 gaaagtgatt gctgtgcctc agcaggtggg gagtttcaaa atgtttcact tgacgctgta
    24601 atcactaatg ttgaaattgg agaacaggaa gaaatccctg accattgggg agcgggttat
    24661 aaaaacaaag taaccatctt ccacaatcaa aatcctgtag ctatcgctaa ctgtgaggca
    24721 gaacataatg gctattatta tagcgtgggc tctctagtga ttggtgatat tcatttccca
    24781 gtagtccatg cttaggaggc tgatatgaga attaagacgg aaagcggagg agttggaaga
    24841 tgatggaaga gttaaagcaa aaagttaatg aagtatacaa ctggacggta gaagacggga
    24901 agccgcaacc tcccaagcaa gatttaccac aagcagtgaa agaccgggcg gactattttt
    24961 gggaaatggc agaagatggt atgacgttta tgggagcgat ggaatgcatc ttcgctgatg
    25021 aaaagcctac cgactatgat ttgggagcta ctaagggttg gttgccaaaa tctaaggagt
    25081 ttgatgattg ggttggctat tcgccaagca tgtctcagtt agttattgca gtttatttga
    25141 tttacagagg aagcgaagat gaaacttaat gaattgatta agaaatataa aaaacttgag
    25201 ggtgtatgga atgctgaagg agcagaacta gctcgtcaaa tttttctgca agacttggaa
    25261 caactagacg aatccgaaat aggttacgca gatgaagctc cacgctacgt aaagaacata
    25321 ctagcacgat tgcgagaatt gccattgcat gatagagagg tttggttaaa ggctatcatg
    25381 agcgaatttg aacaggattt tagccgtgca aaatggcgag agggctacga gcaaggtaaa
    25441 attgagggta tggttgaacg tgaaaaagtc aaagttccgc ggtttgtggc tgaatggatt
    25501 gaggaagcta gaaaagcttg taaagacgtg gtagaattat tcgaatttga tttcacgaac
    25561 gatgaagtta gaaaatggtt tatgcaagaa agaccatttg atttagtagc tagagcatgg
    25621 cttgacggct acgaggtcga ggaagagaag cggtatttgg tgactttaaa aaataggcag
    25681 cctttggtca aatcgcaatc agggagtact ctttatttta gtcaagatat aacagctagg
    25741 aattataaag gtactcaaaa agaactagaa gaagctggcc tcggatgggt gttcgattgt
    25801 gaaggtgttg agattgagga ggtggagtga tgacacaaac agctgaaagt tgcttagaag
    25861 aaacttatga agtcatcaag gaccgcaaag gtaagatgat tgacggggtg tttgttaaag
    25921 aagagtatta tggagaataa agatgccaaa ttttgcagaa ggaacaatta aactaagagg
    25981 acatgcagaa aatattaaat cggctttgaa atatatgttt gaagctgctg gtgatgtcac
    26041 aatcgaagaa gatacagatg gtgagctaat cattttcact tcatcaaact cttattttta
    26101 catcaatggc acaaaacgtg cttttatcga cggtgaaagt tttgaaattc atcttgatga
    26161 tgattttctt atcatcgagc ttaataattt tacgcaggca tggcgcgcta tcccagacaa
    26221 ttacatagaa atctctgaaa aatttaatgt tgacattaaa atctttacat ttgaacaggg
    26281 cttggaattc actcaagaaa tcgaaatttc aaaagggaaa attttaaaag acattgtatt
    26341 gaagtatggt gattatagat gggaagtcgc atttagcaat ttagggggat gaacagaagg
    26401 aggatttggc atgataccga aatttagagg gttatccatt gacgaaaaaa gcaaaggaga
    26461 atggcaatac ggacatttaa ttgaagatag aggaagagca tttattatca gcgaagtggt
    26521 agaagccaat gaacaataca ttactatagg ttcttggtgt cctgtaaatc cagcaacatt
    26581 aggacaatca acaggactca gagacaagaa cggcaaggag gtttttgtcg gagatattat
    26641 caaatgcaca agaggatgcc ttcacgaagt ctatatagaa aaagaatatg gcggtacgta
    26701 ttttggagga atgccagctg tatacctaaa agacttgaga gaaggatatg cgtggactga
    26761 gcatgaagaa atcatcggca acatctacga aaatccggag cttttggagg tcaacgagtg
    26821 agatatttta aaatcctatg tattgtttta ttcgcatcct tactcgtagc atgtcaccag
    26881 atttcgagtg ggacagtggt agataagtac attgatgaac ctcacacaac gttcatacct
    26941 gttataaatg gtaaaagttc ggtacttgtg ccaaccagaa ccaaaagaaa atacattctg
    27001 gtcatttcag gatatgcagg caataagcaa gttgaagaaa ggtttgaagt gacagcaaat
    27061 gaatacaagc actatgaaat tggcaatact tttatacagg atgccgtttt agaaaataag
    27121 gaggaggata aggaatgaaa ccaaaaaaat atccgtattc aggaaaaatg caaaaaatcc
    27181 cgtcgccaat attttctgca cgaccaattt ttaacgaggt tccaattgta gaagaagtta
    27241 aggttgagtt cggagttgaa gctagtatgg ggcgcatata tccagaaacg ttaatacatt
    27301 tagatatttc tggatacgga aatagagtgc attcagtaca tcgcttcccc ggtattttac
    27361 tgagtgttgg tgagtcaatc caactaaaga tgcttttcta taaaagactt agaaatttta
    27421 ctacagatcg tttcttgacg tttagagaat ctgattggaa gttctttatc cgggacctgg
    27481 tcaacgaatt taagcattaa aaaaagccaa gacactctct gcctcagcta atagttctcg
    27541 caaagactat tatatcacaa aggagacaga gagtgaacaa ggctaaagag ctcttgaaag
    27601 agttgcagga tctggacatg gacatccaaa gccgtataga cgaaattaac gagcttgagg
    27661 caggtttgct ctcaagccct aaatggtccg aggttaaagt ccaaggtgga cagactagaa
    27721 aagttgatga tgtctatact cagttggtag tgatgaaaga ggctatagag caggatacta
    27781 aagaggtcat taacagaaaa cttgaattag gtagaatgat caataggctt aaaaatccaa
    27841 agtacagggc agtattaaga atgacttaca tcaacaaagg caccgctgat agcgtttgtt
    27901 atgatttgaa tatgagtcgt acaacctact acaggttaaa aaatgaggcg gtcttagctt
    27961 tggaagaagt tatctaacct catagtgagc ttatgggact ttttggaaca gcacggttct
    28021 aaaaatctgt tagaatggta gtatcaagaa ttgaaaagag aggtctcaga attggtagat
    28081 ggttacctgt aatgtcaggg ggctgtaatg gccttggagg ttcaagtcct cccctctcct
    28141 ttgagtgttt gtgtcccaga atgagttaaa tcttctgggt ggggattcac atatcactca
    28201 ttaactccta tcactcatta acttaaaaat ggttgcggaa gcgactggac ctcgcatgat
    28261 tgcgtagcta attatattcc ggataagtta taagctagag ggtttgattc cctcagaggt
    28321 tttaaagact acaaaaaata aaaaagaagt caaaatttaa tacgcacgca aggtagtagt
    28381 cgccttgcaa gaaggtcgca catcgtgtgg cttttttgat tgtttgaaag gtggtgatgg
    28441 aaaattgagt ggattgagaa taaaacaaaa gagatttgca gatgagtaca tcatctcagg
    28501 taatgcgacg gaagcctata agaaagcagg ttatcgtgtt tctagtgata gagtggcagg
    28561 cgttgaagga cataagttac taaagaatcc taagattaaa agctatatag atgaacgact
    28621 gaaacagctt gattctgaaa agattgcgga tcagcaagag gtcttaggtt atctaacttc
    28681 agtcatgcga ggagagacgc aagaacagac cttgataagc attggagaac tagggcagac
    28741 gattacggat atagatgtag gagctaaaga tagaatcaag gcggctgaac ttcttggtaa
    28801 acggcatagg ctttggacgg ataaggtaga ggcggatgtt tctggaacgg tggtgtttgc
    28861 aaatgagtca gacataccag attaagcaaa gtgatattgt aatcgaccta cctaagacag
    28921 taggagctgg gtacggacag ttctggcgct caagaaatct ttatcgtgtt gtaaaaggtt
    28981 cccgtggttc gaagaagtcc aagacaaccg ctttgaatta tgttatccgt cttttgaagt
    29041 atccctgggc caacttgctt gttattcgta gatactcgaa taccaacaag caatcaactt
    29101 atacggattt taaatgggcg tgtaatgtgt tgggtgtgac tcatttgttt aaattcaatg
    29161 aatctttgcc tgaaataacc ataaaagcga ctggtcaaaa aatcctattc cgtggtttgg
    29221 atgatgaact caaaatcaca tctatcacgg tcgatgtcgg cagtctttgt tgggcatggt
    29281 ttgaggaagc atatcaaatt gagactgaag acaagttcag tacagtagtt gagtcaatcc
    29341 gtggtagctt agatgtacct gatttcttta aacaaatcac agtcacattt aacccgtgga
    29401 atgagaggca ttggctcaag cgtgtattct tcgatgaaga gacgagacgg gctgacacat
    29461 tcgctactac aaccacttat aaatgcaatg agtggcttga tgaagtcgat atcaaacgat
    29521 atgaggattt gtaccaaacg aaccccagac gtgctagaat cgtttgtgat ggcgaatggg
    29581 gagttgctga aggtttaatc tatgagaacg tgaccgtcaa ggatttcgat aaggatgaat
    29641 tgctacgaga ttcagctaat aagttatgta tcggtcttga ctttggtttt actcacgatc
    29701 caaccgcttt gtgttgttcg ttgataaatg acacgacgaa agagatttat gtctttgatg
    29761 aggcgtataa agtcggattg ataaccaaag aagttgcgaa gatgataaag gacaaaggtt
    29821 atcatcgctc acaaatcatt gctgatagcg ctgaattacg actgattgag gaattaaggt
    29881 cagaacatgg tataactcga attaaagaga gtcgtaaagg taaggatagc attatggctg
    29941 gcgtgtccaa gttacaagga tacgctattt atgtgcatcc agactgtaaa aatatcatgg
    30001 atgaatttta cagctattgt tatcaacaag acaaagaagg aaattggctg aataaaccag
    30061 aagataaaaa caaccacttg atggacgctt tacgttacag ccttcaatgt atcgaaggtg
    30121 gaaaagcaac cgtccgcaga cgttctgatt atggtctata gagaggaaag acatgtacca
    30181 atatttaacc tatccacggg atggatatga tgagggttct ttgaagaaag acctgattta
    30241 caaattgata acgatacata gcactgaaag ctcacatttg aagaagctta aaagctacta
    30301 tttgggtgag catgctatct tagaacacac gagacgcaac gtgaacgcac ctaattacaa
    30361 gacggtagcc aatcatgcca aggatatcgc agacacggct acgggctatt ttatgggcaa
    30421 tcctatcaag tataacaata ctgctgacgg tgatatcgat gaactactta cagcctttga
    30481 tggtgctgag attgaccaag tagatgctca gaatgctttg aacatggcta tctatggtcg
    30541 tgcttacgag tacatctatg ctaaagaggg tatggctgag ttggattcaa ctagtattga
    30601 tccggagaat actttcatgg tctacgatga tagtattgag cggaagcctt tgtttgcggt
    30661 ctattactat gaagtaaaag acgatacgaa agacactacc aagtaccagg ctgaggtctt
    30721 taccgaaaat ctgcactatc acatggtgct gagaagtaca gattcaggaa caactcagag
    30781 cgaggaggca acacctcaca accttggtca aatcccaatt atcgaatatc gcaacaatca
    30841 ctttgcaatt ggtgactatg agcaacaaat tagcttgata gacgcttata attccttgat
    30901 ggggaatcgt gtcaatgata aggaacaggc tgtagagtct atacttgtct tgtatggcac
    30961 gcagttagca gacactccag aagacgctaa ggtagcaatg aagattcttt ctgaagaagg
    31021 tcttttggaa ttgccgggcg atagtgcaag ggctgagttc ttgaagaata cgctggatga
    31081 aagtgctact gaaatcttgc gtacagctct taaagaggac atctacacat ttagccatgt
    31141 gcctaatttg actgatgaga atttcgcagg gaatacatca ggcgtagcca tggaatttaa
    31201 gctgatgggc cttgaaatga ttactaagac caaggaagcg aactataagc gaggattgcg
    31261 tcagcgtatt gcgatttttg ctcattactt aggcatgaag cagattgctt tagagtctca
    31321 ttcaatcgtt ccacaattca gtcgtggttt gcctaagaac ttattagaaa tctctcagat
    31381 tgtgaacaat ttggaaggca aagtgaccaa tagacagctt atttctctct tgccgtttgt
    31441 ggaagaccct gacgctgagc tggaagcctt ggaagaagag aaaaagaaga acatggaaga
    31501 catgccgatg ttcaacaaag acaacacgaa acccgaagac gaggtagagg atgaagaatc
    31561 aggagtattg ggcgaagagg aaagccaatc tgatttacca gcagatggac aaggccgaaa
    31621 agcaggcaga ccagttcgat aaggtctatc aggaagccaa gacttacttg gataaggaag
    31681 tcaataagat ttttgataag ttccaacgtg attatggtct aagtcaggta gatgctagac
    31741 aagtcttaaa gaacatgaaa gacaagaaaa atctgaatga acttcgtaag gtgcttgaag
    31801 caagaccgaa tgatccaaat atccaaagac tactggctga cttagatagt ccggcttatt
    31861 ctttccgtat gaagcgtcta gaacgtttga gtgatgattt agaccgtatg cgtgaatcta
    31921 tctatcattc agaaaagaca ggctcagacg ccttttatag cgacctgatg aaggatagtt
    31981 actacaaggc tacctttgac ctgcagcagc agacaggact agcatacggc ttttctgggc
    32041 ttcctgagag cgagattaaa catctacagt ctttcagttg ggtaggtgac ggaagtacct
    32101 actcaacaaa catctggaag aatacaggga agcttacatc aagcataaaa gatgaattac
    32161 tcataagcct tatgacaggt cgagatacac gagaaactgc acaagcaatt gctgagaggt
    32221 tcaatgtagg tcagaacgat gcaagacgtt tggttcggac agaatcagcc ttttttcata
    32281 accaaatgga actactcagc tatgaagaag cagacataga aaagtatatc tttgtggccg
    32341 tcttagacaa gcgtacatca cggatttgtc aggagcatga caatcaggtc tatgataggg
    32401 acaaggctgt ccctggcgtc aattgtccac ctatgcatcc gtggtgcagg tctactactg
    32461 tcggatacga tgaggacgca gactacagca agttgaagcg cagagcaagg aatccagaga
    32521 caggtaaagt tgagtacgtg cctgccgata tgacttataa agagtggtat agcaagtatg
    32581 ttgcgaaaga cggggaaaag gtgtataatc aagatacaag agaagccaat gcgaaatttt
    32641 atagcgaaca actattgtcc aaaatttcag gagttgagcc aaaaattaca agtgatatgc
    32701 aacgtatcgc aggagaaaac aaattggcag gtcttgaatt taggaagaaa acagttgagt
    32761 cattatcacg taaaattatt gcagatagcc tagttgaaaa tataagtttg tcaaaagccg
    32821 tgagtaagat taatgacgcc ttaaggtaca caactatttt cgattccgat acttttacag
    32881 aagagtattt gaagatgaaa cagaagctta tcgcagaagg ttataaaatt gtaaaagtaa
    32941 aaaacacttg gctagtagat ggaccataca aaggtgtgaa tacagtcgtt gaaaaagatg
    33001 gtatcaactt tgaaatgcag tatcatactc aggaaagttt cgacttaaaa aatggttcat
    33061 tacatgaact ctatgagaag tatcgtgata cgaatacatc tgatctagaa cgcatgaaat
    33121 tatttaagga aatgcttgat ttaagcaatg ggcttgagat tcctaaaaat atagagaggg
    33181 tgaagtgata tgaaagatat taaatactac cgcacaacga cgaacaatgc tcaagtactt
    33241 cgtttgattg atggtgtcat gcaagttttt gacattgaaa aaaagtgggt taatagcatg
    33301 gattggttta ataaaatctt ttttaatgac tttacggatt ttgaagaaat ttcagaaaat
    33361 gatgcattta cttatattga caggatggta gcggcatgat tgatattgcc ttggctatcg
    33421 ctaaaaaagc acatgcaggg caggtagata aagcgggtgt tgattacata cagcatcctc
    33481 tctatgtggc cagtcaagtc aacactgaac aagaaaaagc tgtcgctctt ttacatgatg
    33541 tgattgagga tagcgatata actgctgccg atttattggc gtctggtttg tcaaatgaag
    33601 ttgttacagc ggtacaaatt ttgacaaaga aaaaaggtca aagttatcaa gaatatcttg
    33661 ggaaagtaaa atcaaataat ttagcaagag ttgtaaaact tgcagatttg aaacataact
    33721 cagatttatc acgtttgaaa tctgttacca atacagacta cgagcgtgtt aaaaaatata
    33781 aaaatgcaat ttattactta agcacctaga gaaatctaag tgcttttttc gtgctcagaa
    33841 aggagaatct gatgaataag tacaaaaagt tgatagaatt gattgaaaat aacggtcttg
    33901 agatacaatc taagaaatgt tatgatccac agagtgcttg gcatggtgag gagttatgga
    33961 ttgttgataa gaaaaaacaa aataaaattt ttgatttatc aggtaacggt tactgttttc
    34021 atgacgctaa agttgaggaa gccattgaag aagttgagaa gtatctatta ttgaaaaaga
    34081 tggatacgtt tgatgatttc aaaaaatggg tggaaaagaa tgctaagcct aaaaaatgat
    34141 gcttagaaag gagtaaagac atgtttatat gggattgggt atcaatcgcc tttgggtggt
    34201 tggtattttt gttgttaata tttattatta tggccgtaat cagcggaata attaaaggtg
    34261 taaagaaagg aacagaaaaa tggaagaatg gaaagaaaga tttaaaaaag aatactacga
    34321 attgaaagaa cgattccaga agttagatat gatgattggg aaatacgaaa aagggcaact
    34381 agagtttgaa tctaaatgtc cgattgattt gttaaaaggt cagcgttcaa ccatgtggaa
    34441 ttatttaaga attctagaac aacgtgcaaa aattgaagaa attaaactat aaaaattaac
    34501 cgcatcgaaa tcgaggcggt tttcttatgc tctaaccgta tggaatcccg tacggttttt
    34561 atattgtcca aactgtgccg atgacattaa aagctgtact gttccgtcgc cggacgtaaa
    34621 gcgagattat cgagtggcga cgtaatcgct ggaggacaat tatgtcagaa gaaatcaatg
    34681 caactgtatc tactgaatca actgagactg tcgacactca agaaaatgtt gatacagtgc
    34741 aggaagaaaa gcacgaacga actttcactc gtgctgaaat cggtaagatg ctatctgccg
    34801 agcgctctaa atgggaagct gagcaagaag ccaaggaaaa cgaagctaag aagcttgcta
    34861 agatgaacgc tgatgaaaaa cagaaatatc agttggagca gcgtgagcaa gaactagctg
    34921 accgtgaaaa ggctattgct cgtaaggaat tgaccgcaga ggctaaagca atgctaagtg
    34981 aacgtgactt acctgttgag ttagtaaatg tagtcgattt gacaaacgca gagacggtat
    35041 ctgaatctat cacctctatc caaaaagcat gggaagagtc agttcagaag ggagtctctg
    35101 aacgtatgaa aggtagtgca cctatcaaaa atgcacaaac agtccagcaa gaagtcacgg
    35161 aaaaatggcg taaagacttc ttgtaataaa agaaaagagg aaaaataaat ggcatttgaa
    35221 gaattaaaca cagcagaatc acgcaagaaa catcttggga ttattgagga tgtacttgca
    35281 gtaaattcat attcaacacc acttgtgaca tcaagcgatg cagtaacctt gcaaggtcgc
    35341 tcttttacag tagcaactgg taacacaaca gagttgaaag actacaaacg taacaaagac
    35401 aacgaatttg atcacgttga agttgaagaa aaggtttata cccttgatga agaaaaatac
    35461 tggggtcgtt tcgtagatca attggacgaa cgtgactcta atggtcaagt gaatatcaat
    35521 tatgttattg cccgtcaggc tgcagaagta gtcgctccat atcttgatga actacgtttt
    35581 ggtgcagcac ttggaaacgt aagtgacaat gttgccatgg gtaacacagc aggagcgaac
    35641 aacgcttata atgcggttct tgatgtgtct gagaaacttg atgagcttgg aattacaaaa
    35701 gaacgcttgc tcttcgtcac tccaagtttc tacaaagcga tcaagtctga aatcgttcgt
    35761 ctaccacatg gtgacgcaga taagaaagtc cttggaaaag gatatgttgg tgaattggat
    35821 gattacacag tctataaggt tccttctaaa ttcctgaaag gtgttaatgc ccttgctact
    35881 gctccaggtg ttgttacatc tccagtacaa gtagataata ctaagtacaa cgataacatt
    35941 ccagggcgat ttggcgaatt ggtagagcaa ttgctttaca ctggtgcatt tgttcttgaa
    36001 cacttcaaga aatacatcat cacaattgca gattctaagc ctgctgctaa aaaatcagta
    36061 caaggtaaag ttgtaaaccg tgctaaagcg tggaaaactg gaacaactta caaagaaggc
    36121 gaatcagtaa ctcatgccga taaagtctat gtagcggtta aggatatttc taattcagca
    36181 accgcaccag acacagatac aactaactgg aaagaaaaaa ctggtaagaa ataggtccga
    36241 gttatgaaat ttaaaatcaa acaagatttc tatgattggg aatcaaatgt gaaacgactg
    36301 gtaggggagg agcttgagat tactgaggaa cgatatgccg agctggctga caatattgcc
    36361 agcaacggtg tcactatctc agacgttctt gagaaaatcc tccctgaacc tgagttctta
    36421 gaagaggatt gatatgtcta tagagttgct gaagaaatta acaggcgaag aagatactca
    36481 gcttctcatg ttgctccaaa cgagggctac aagtcttatc ttgtcagaga ctaatcgcac
    36541 atctttgaca cctgctttaa gtcttttgat acctgaggtt gctatcgagc tccacaaccg
    36601 ctcaggagcg gaaggagagc attctagaac cgagggtggt atagcagtag tctacggaga
    36661 aaacggccta tctacgggtc ttctacagcg aatacgcatg cacaggctag caagggtggc
    36721 aggtcatgtt tttgaagcag agtagactga aaccctatcc aatgcgacgg tttgaaaaga
    36781 ctgtcactga ggaaggtgtc gcgaaagaag ggtatgccaa ggaagctgag acagtccgcc
    36841 ttgaattgtg gccagctagt agcaagctac aatctgaatt gtatggcgag cgtgtcaatg
    36901 atattttgaa cgcaaatgcc aacaagtcag ctactatcaa agtaaaagat ggtgtgtgta
    36961 tcgatagtca gacggaagtg actcataggg ttatttctaa aaaggtctac acacatcatc
    37021 aagttttgga gttagagcgt gtcagggcta ctaggggcag ataggcttat agctaaatgt
    37081 agacggttag ctagtaaaaa aactggcgag gatatcgtct tacgtgcggt acacaatgct
    37141 gctataaaag ttgtccaagc tgatgcaaga agactcgtac cagtgaatga tggagaactt
    37201 ataactagta tcaaaaccag agcaaaaatg gacggagata gggctatagg cgaagtttac
    37261 accaacctta aatacgctcc ttacgttgag tttggaacgg gacctaaggg tcaggctagc
    37321 cattctggta tctctccaga ggtcagcgtg acttacaagt ctcatccttg gtatgtgcat
    37381 gaagaccaaa tcaatgtagg atcttaccac tttcaaaaga ttggggagtt ttacaagatg
    37441 tatggtcaac ctgctcagcc ttatctttat ccagctttga gagacaatca agagcgtgtg
    37501 tctaagaata tttcgaatta tgtccgtaga aagataagag aacaaataca atgatcaata
    37561 tcaagcctgt tatttataaa gaattgcaaa aggttgcaga taatgtgacc gatacttatc
    37621 ctagcgattg ggagactttc ccagtcgtta tttttttaga agaacaaaac aagccaggtg
    37681 attggtttga cgacaaggaa caaaaatcct ctatccgcta taaggtggat atttttgatg
    37741 ataccagcac tagtgagtta gctgttaaaa tcaatcagat ttttgagtct ttaggtttgc
    37801 gaagaaccga ctgccaagac gtgccagacc cgtctcattt gagacataag gtcatgcgtt
    37861 ttgaaggtgt cgttgactta gattcagagc ttgtttttca atttagaatg gagaattaaa
    37921 catgttagca aatggaatta aattggcctt tagtgaaacg aaaggcaatt atcagaatct
    37981 tgtagggctt aaggaagtac ctgaatttgg tatcgagccc gaaaaagtag aaaatactac
    38041 ccttgcagat acagtgaaga agtacgagtt tggtatcggg gacgcaggag aacttgagta
    38101 caagttcgct tataataatt caagcgcaac agctccttac cgtgtattac gtaaggcagc
    38161 agatggtaag aaaaaacttt actttgagca aacatatcca gatggtacta aggtcacttt
    38221 tgaaggtcaa gtatctgtta agcttggcgg tggcggtgtc aatgccgtta tcgagttcac
    38281 acttaagatt gccttgcagt ctaatcttac atttactgat ggtgttggag gttaattaaa
    38341 tggcgttaaa atacacaact tggaaagtta ctgacgaaaa agagttgaag ctacgtttga
    38401 catctcatca agctgcaact gtggaagaaa aaatcggcat gaacttgctg aagattttca
    38461 tgcctgaagc tggcgaagag ttcactttac cgcctttgaa agttatgttg ttgttagttc
    38521 acggcgcctt gcagcagtat gaacatgggt attctcttga ggatgtctat gatttatacg
    38581 atgaatacgt ggacaatggt ggagaccaaa caacattcat gacagaggtt ttaatgccac
    38641 tctttgaagt atcgggtttt actccacgag gaagcaaggg caagaaaact tccaagaaga
    38701 aaatgacagt agtcgagtaa ttttaacagt aacgcagatt attgagaggc tttatcctat
    38761 gtttttggac atcgggggca agcctcttga tttttgggat ttgacggtgc ttgaaatcag
    38821 ggaaatgata gaaagctaca accgtgtcaa aatccaagag cgtaaagaaa agattattga
    38881 ctcgtacata ctttcgcgaa tgataactaa tcatgtttcc ttattactgt ccaatgacgc
    38941 taagattgtt gagctttggg aatatgcgcc tgagttgttt gtagaagaac agcaagcagt
    39001 agaacaggaa cgacagagac aagcgctttt gttgcataag gaacggatgc gtgattttgc
    39061 agagagacat aatcgaaaaa ggaaggagga agtaaatggc aactcttgat gaattgaagg
    39121 tcatgattga cgctgagata gcgcctttca ggaagaagat gaaagaagtt gagaatcagg
    39181 tcaaaggaac atctgaccaa gtgaaaaatg ccactgctaa agttcgtgaa cagtcgaact
    39241 caataggtag tgcgtttggt aagctggcta agttcgctgg ttttgcaatc cttggtaaga
    39301 aattacttga tgttgggatg tattcaacgc agacggctct tgaagtatca gcgtctatga
    39361 accaaatcaa gcgacagatg ggcgagagtt cgcaatcttt cttaaaatgg gttaacgata
    39421 acgccaacgc tatgaatatg ggggtgggtg aggctactaa ctacggtgcg gtctactcaa
    39481 acttattttc tgggtttatc aaagatacca acaagctaag cgcctatacc gctaagatgt
    39541 tgcagacatc ggcagttgtt gctgaaggtt cagggcgcac gattacagac gttatggagc
    39601 ggattcgctc aggtctacta gggaacaccg aagcaattga ggacctagga atcaacgtca
    39661 atgtggctat gattaagtcc actgaagctt ttaaacgttt ctcaaatggt caaagttggg
    39721 accaactcga ctttcaaacc cagcaacaaa tccgtcttat ggctatcctg gagcaagcta
    39781 cagccaagta tggagatacc ttgtctaatt ctgtaaatgg tcgtatcagc ctgtttaagt
    39841 cgctaatgaa ggacgcagca ttgaaccttg gtaactctat gttaccgatt atcaatgcca
    39901 ttatgcctgt cttgaactct tttgctatgg ttttgaagaa cgtgacggct aaactcgctg
    39961 agtttatcgc tttgatgttc aacaagaaag caacagtgaa agatggtgtt ggtggagcag
    40021 ttggagacat gggtaacgcc atgaaagacg ctgcaggcgg agcaggagac cttgctgacg
    40081 cagtagacga cgctggagat tcagcaggag gacttgctga caatcttgga gactcagcca
    40141 aaaacgctaa gaaagctgct aaagagttgc taggtctttt gggatttgat gagattaaca
    40201 tcttgcaaaa accaaaagat gacgacgcag gcggttctgg aggcggtggc aaaggtggta
    40261 aaggaaaggg aggcggtggc ggacctttca aagacatctt gccagaagtc gagttgaccg
    40321 acatggacaa caaattcaag agcatttttg atggtcttgg agataagctc aaagggttgt
    40381 ttgacctctt caagaaaggt tttgatgcag catttagacc agaaggtata aaacgcatta
    40441 agactgcctt agaccaaata gctaagacaa tgggagaaat cgccactgac ccaagggttg
    40501 tgaatgcctt taaccgaatg gctgagaaaa ttgcttatgc tttagggcaa gtgacaggct
    40561 caataaccac tatcgggcta ggtatcggtg ttttccttgc cgaaagtatt gcaaatggcc
    40621 ttggaaggca aaaagaacgc attatcaggg cgctagtcgc tttgtttgat aatgttggta
    40681 acctttccga ggcagtagga aacatagctc aggacttttc tagtgctttc tacgacgtca
    40741 ttacctcaac tggtgcggtt cgtatcggta gcgctattgt gtcaactctg ttgagtttga
    40801 catctaccat tgttgaagtt ggtagtaaat tagcaggaag tttgtttaaa ggttttgaaa
    40861 aagtcgttgt gacaagcgct cctaaaactt catcagtctt ccaaagttta ttagatactg
    40921 ttgcgcctgt atttgagagc attgaaaggt ctgttaacaa atttggcgat ggcttaagtc
    40981 gtgtttatga tgaacatgta gtccctgcta ttaactctat tgctaatgct tttaatgggc
    41041 taattgacat tattcagatt ctctgggaga attcctggca accttttgct gagtttttat
    41101 caggagtatt cggtgttagt attgaaggaa tttcagattt attaggaggt ggccttttag
    41161 ccactttggg actattggcg gatgctatta agttagtggc agatggtttc accgtttttt
    41221 ctgactggtg taaagaaaac aaagaaccta tcgtagcttt gataacaact tggcaaacga
    41281 ttaatttctt atcatgggca gaacaagctg gaggacttgc aggagcattc agcttgttag
    41341 gtagtaaggt ctctttgatt gttggaggga ttaagaatct aggtcttgct attaaagcat
    41401 tgacatttga taagttggtc agttttggtg aaacaatcta tttgaacacc ttatatgcaa
    41461 aagattttgt ggtcaattca ggtaaaacaa ttgcacagct aggaaaaact gctttagaac
    41521 ttggtaaatc agctctagca tggactgctc atgcagcgaa aatgggatta gcaaccgcgg
    41581 cggaatttgc acattctgtt gcagcaggag tcgctacagc tgcaacatgg gcttttaatg
    41641 cagcgttagc agttttgaca agtccaataa catggattat tgcagcaatc gcagctttga
    41701 ttgctatcgg tgttttgctc tatcaaaact gggacactgt tgttgagttt gctaaaactg
    41761 catggcaagg actatgtgat tttatcagtg gtatttgtca agcgattggc gaatttttca
    41821 gcggtctatg gacgaaacta caagaaatct ttgagccgat aggtcaatgg tttggcgaga
    41881 aattccagca agcatgggac gccattgtaa acatattctc tggcatcgga gagtggttct
    41941 ctggtgtatt ccaaggtgca tgggacgcta tcgttaatat cttcacacca atcggctcat
    42001 ggttcggaca acgttgggca gatgtgacta gtgcgttggc taatatcggg gcatggttta
    42061 ctgacatgtt ccaaaaagca tggactggct taacaaacat ctttagcaaa ctaggttctt
    42121 ggtttggcga gagatggaac gatgttacaa gtgcactttc caaagtagca agctggtttg
    42181 gcgatatatt cggaaaagct tttgacgctg ttaaaaatgc ctttagctct atcggagact
    42241 tctttaaagg cgtttgggat actgtcaaaa gtatcttcgt taatgctggt cagatggtcg
    42301 gcgaggcagt aggtggagcg tttaagagtg cggttaatgc ggttcttgga acgattgaaa
    42361 atgtagtcaa tggcttcatc ggaatgatta atggagtttt aggcgttgtc agaaacttac
    42421 ctggtctagg atgggttggt agtgtaagca cagttagcct ccctcgtctt gcccgtggtg
    42481 gtatcgtcga tagtccaaca atcgccatga ttggtgaagc tggtaaagag gcggtcgtac
    42541 cacttgaaaa tacaggattt atccaaacac ttggacgagt agtcagcagt gcggtagtaa
    42601 atgccatggc tggtgttagt ccacaaagtg gattctctgg cgacggcgac atcgttatcc
    42661 aaatcgcagg ccatgagttt ggacgggtag ccatccaaga aatcaacaag gaacatgaac
    42721 gagcaggtca aaccttgctc aagatttagg aggttaaatg gcacaattga caatcaatgg
    42781 ggtggctgtg aagcctccca aatcttttca agtcggtatt caagatatcg atggagagac
    42841 agggcgtaat gccaatggcg acatggtgcg tgaccgtatc acgaccaaac gcaaactaga
    42901 ctgtgaatgg ggtatgatga ctcagggaga aataagtcag cttttacatg ctgtatcatc
    42961 taaatttttt gaggtatctt atccagaccc catggatggc caagtcacaa agactttcta
    43021 tgtcggtgat aggacagctc ctagctatac ctttactgag aagtttaaac cttggtctgg
    43081 cgctaaattt aatctggtag agaggtaaga aaatggacgc tttaactaga cgacaatttg
    43141 acagagccat gtttgccaag gaaaggacgc tggctattcg tgttggtgat tatgcttcac
    43201 gggatatcaa agaggctagt tttgagtatg gctacattaa gggcgatact tataagcctg
    43261 gtggaacctg cgctggtagc ggtaaaatta cctttaccag tatcattacc acgttcaata
    43321 agctggatac cctgcaccct gagattggtc tactggttgg ggatacctac cagtgggtca
    43381 agatggggga atacttcatc aacgatattg agattgaccg aaaccgcaac acaaccacac
    43441 ttgaacttat ggacggtatg tttaagctca atcgtgagta cgtgacggat ttgcatttcc
    43501 cagctgaagt acgagaggtt attcaggaaa tctgcctgaa aacaggcatt gagttagcga
    43561 atgactattt cggaatcagc gcgatgcgtt atcatattga gcaagttcct gagggcaaga
    43621 aactttcctt tagggatatg ctgagcgcta tgactcaggt gattgggatg tcttgtttct
    43681 tcaacagaga aggcaagatg gaaatccgtg atttgactga gtccaatatc acgatcaacg
    43741 ctgacagtta tttcttgcat ggcttgacca agagtgagat tgagtatcag atagctggta
    43801 tcacttgtaa gacggacaag aagtctctga cggtcggtat gaagacaggt cggtctttgg
    43861 aactggacaa tgtcttcatg acccagagcg ctttaaatga cctgtattac aaactgaaaa
    43921 acctaactta ctatccgtat aatctcaact accaagggca tttactgctt gaggttgggc
    43981 agtgggtaac cattcagacc aacaagaaag aaacctttaa agttcctgtc ttaagtcaga
    44041 gctttacttt caaaggtggt ctaagaggtc gtatcagcgc agatagtaaa gctggaaatg
    44101 atacgcagta ttcttacgag ggtacgatta ccaagcagat taagcaacaa gatggcattg
    44161 aagccaaaat ccaagcgcag atagaagcag cagacgcagc ctttgacgct gaatttgaca
    44221 aacgtgagaa agctatcacg gatgccatcg aacttgccaa agccagagct gaagaagtca
    44281 agagagaact gtctgacact atcaatcagc gctttaatag ctttgacaac gggccattga
    44341 aagaaactaa gcgcaaggct gaggaagctt tgcgaaatgc tggcgcaagt accctgcttg
    44401 cacaggaagc taagcggatt gggctggatt ctgtcgctag acttgaagcg tttaagtcgc
    44461 agactacgag cgcacaaacg gctctgtcgg gtgacttgga cgctctgaaa cggactatcg
    44521 cgaatgatat tcgaccgaag caagcacagg ctgaagctga gattgccaag caagttgaag
    44581 cacttagccg gactaaaaat gaactggatg gcgcaagtac cctacttgca caggaagcga
    44641 agcggattga gctggattct gttgctagac ttgaagcgtt taagtcgcag actacgagcg
    44701 ctcagacggc tttgtcaggt gacttggatg ccctgaaacg gactatcgcg aatgatattc
    44761 gacagaagca agcacaggct gaaactgaga ttgccaagca agttgaagca cttagccgga
    44821 ctaaaaatga actggctggc gtgaagtcag cgcaagcgac gtatgaggag acgacgactc
    44881 gtagactgtc agaactgacc aacttggcca atggtaaagc cagcaagtca gaacttacgc
    44941 agacagctga ggagctagct agtaagatag cgagtgtgca cttagggcgc agaaatctgc
    45001 tgaaaggcac aaaagagctt gcgagataca agccggttag tgaatataat ggttttaaag
    45061 ttatcagaac agtcgcagga gcaactagat atcaggatag ctatgtggaa agaaccgtta
    45121 taccaacggc tgggacagag tatatagcta tcttttatgc acgagccagt gaaaatgact
    45181 atcctgtgcg ctgtcatttt tacaatccta acacggttgt atcatcagaa aacagcagcg
    45241 gatataagtc aaggtcgtca gatggcttgt ctattatccg tctctcgaca gactggcagt
    45301 tgtgctgggt taaatggacc caaaccgcaa cagatcaagc caagacggtc atcattggcc
    45361 gccatggccc tcaagtaggc ggtaaagagg gggtatgggt tgaaatctgc gcccctgcca
    45421 tttttgaggg aaatcttgca ggtgactggt cacctgcata cgaagaccaa gacgaacgtg
    45481 tctcagcggt cgaatccaac tttaaacagc gtgctgattc actcgaagct ggtgtaagcc
    45541 gtctgactga aggccttaga accaaagccg atatcagctc actcaacgta actgctgaga
    45601 atatccggca atctgtgaag agtcttgaga cagacacgca gaacaagcta aatcagaagt
    45661 tgagtcaggc tgaatttgag gtgcgagccg gctctat
//
LOCUS       DAVLGK010000011        44841 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLGK010000011 DAVLGK010000000
VERSION     DAVLGK010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44841
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.011"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            236..2128
                     /gene="pepO"
                     /locus_tag="VXE01_000704"
     CDS             236..2128
                     /gene="pepO"
                     /locus_tag="VXE01_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV0749665.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2251..2880)
                     /locus_tag="VXE01_000705"
     CDS             complement(2251..2880)
                     /locus_tag="VXE01_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0749666.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            3839..6061
                     /locus_tag="VXE01_000706"
     CDS             3839..6061
                     /locus_tag="VXE01_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV0749667.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYPSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            6091..6534
                     /locus_tag="VXE01_000707"
     CDS             6091..6534
                     /locus_tag="VXE01_000707"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV0749668.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6801..6986)
                     /locus_tag="VXE01_000708"
     CDS             complement(6801..6986)
                     /locus_tag="VXE01_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749669.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(7005..7418)
                     /locus_tag="VXE01_000709"
     CDS             complement(7005..7418)
                     /locus_tag="VXE01_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749670.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(7549..8196)
                     /locus_tag="VXE01_000710"
     CDS             complement(7549..8196)
                     /locus_tag="VXE01_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV0749671.1"
                     /translation="MVVGIAIASGYLNSHLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(8373..9023)
                     /locus_tag="VXE01_000711"
     CDS             complement(8373..9023)
                     /locus_tag="VXE01_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV0749672.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            9135..9977
                     /locus_tag="VXE01_000712"
     CDS             9135..9977
                     /locus_tag="VXE01_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0749673.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            10053..10490
                     /locus_tag="VXE01_000713"
     CDS             10053..10490
                     /locus_tag="VXE01_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0749674.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            10558..10860
                     /locus_tag="VXE01_000714"
     CDS             10558..10860
                     /locus_tag="VXE01_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749675.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(10951..12024)
                     /locus_tag="VXE01_000715"
     CDS             complement(10951..12024)
                     /locus_tag="VXE01_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV0749676.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            12180..12857
                     /locus_tag="VXE01_000716"
     CDS             12180..12857
                     /locus_tag="VXE01_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0749677.1"
                     /translation="MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMKVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            12850..13824
                     /locus_tag="VXE01_000717"
     CDS             12850..13824
                     /locus_tag="VXE01_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0749678.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(13873..15816)
                     /gene="thrS"
                     /locus_tag="VXE01_000718"
     CDS             complement(13873..15816)
                     /gene="thrS"
                     /locus_tag="VXE01_000718"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV0749679.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(15874..16197)
                     /locus_tag="VXE01_000719"
     CDS             complement(15874..16197)
                     /locus_tag="VXE01_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0749680.1"
                     /translation="MELQELVERSWAIRQTYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            17067..17696
                     /locus_tag="VXE01_000720"
     CDS             17067..17696
                     /locus_tag="VXE01_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV0749681.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            17837..18106
                     /gene="rpsO"
                     /locus_tag="VXE01_000721"
     CDS             17837..18106
                     /gene="rpsO"
                     /locus_tag="VXE01_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV0749682.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            18921..19535
                     /locus_tag="VXE01_000722"
     CDS             18921..19535
                     /locus_tag="VXE01_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV0749683.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(19828..20577)
                     /locus_tag="VXE01_000723"
     CDS             complement(19828..20577)
                     /locus_tag="VXE01_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV0749684.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            20710..23046
                     /locus_tag="VXE01_000724"
     CDS             20710..23046
                     /locus_tag="VXE01_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0749685.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNLAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKMF
                     GASQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            23575..25038
                     /locus_tag="VXE01_000725"
     CDS             23575..25038
                     /locus_tag="VXE01_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0749686.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKG
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFRMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFSELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            25031..25459
                     /locus_tag="VXE01_000726"
     CDS             25031..25459
                     /locus_tag="VXE01_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0749687.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            25437..25886
                     /locus_tag="VXE01_000727"
     CDS             25437..25886
                     /locus_tag="VXE01_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0749688.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            25914..26225
                     /locus_tag="VXE01_000728"
     CDS             25914..26225
                     /locus_tag="VXE01_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEV0749689.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            26251..27336
                     /locus_tag="VXE01_000729"
     CDS             26251..27336
                     /locus_tag="VXE01_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEV0749690.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILRKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            27347..28042
                     /locus_tag="VXE01_000730"
     CDS             27347..28042
                     /locus_tag="VXE01_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0749691.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            28079..30046
                     /gene="tkt"
                     /locus_tag="VXE01_000731"
     CDS             28079..30046
                     /gene="tkt"
                     /locus_tag="VXE01_000731"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0749692.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAVLPTFLGGSADLAHSNMTYIKADGLQD
                     KYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQELP
                     VTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTTT
                     PTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELVL
                     QGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVIG
                     IDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            30416..31764
                     /locus_tag="VXE01_000732"
                     /pseudo
     CDS             30416..31764
                     /locus_tag="VXE01_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(31838..32368)
                     /locus_tag="VXE01_000733"
     CDS             complement(31838..32368)
                     /locus_tag="VXE01_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEV0749693.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPNWKMDLFSEEEKRNYFQTTCEIS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LYNIVNIVSDIHKLGI"
     gene            complement(32414..32830)
                     /locus_tag="VXE01_000734"
     CDS             complement(32414..32830)
                     /locus_tag="VXE01_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749694.1"
                     /translation="MDLLEKECLKCDKNFQQGDIWNYYYLSDKVPAQGWKIHISSQIK
                     DAVNIFKIVYKLSQLNNCSFKVVKNLEELKKINSPREMSPTANKFITLYPKSESEAKS
                     MICNLTNRLSEFKAPKILSDYQCGMHSLVHYRYGAF"
     gene            33379..34056
                     /locus_tag="VXE01_000735"
     CDS             33379..34056
                     /locus_tag="VXE01_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV0749695.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            34043..34840
                     /locus_tag="VXE01_000736"
     CDS             34043..34840
                     /locus_tag="VXE01_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV0749696.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            34857..35960
                     /locus_tag="VXE01_000737"
     CDS             34857..35960
                     /locus_tag="VXE01_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV0749697.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            35961..36041
                     /locus_tag="VXE01_000738"
                     /pseudo
     CDS             35961..36041
                     /locus_tag="VXE01_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            36261..37280
                     /gene="galE"
                     /locus_tag="VXE01_000739"
     CDS             36261..37280
                     /gene="galE"
                     /locus_tag="VXE01_000739"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0749698.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESSDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            37282..38235
                     /locus_tag="VXE01_000740"
     CDS             37282..38235
                     /locus_tag="VXE01_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0749699.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(38297..38503)
                     /locus_tag="VXE01_000741"
     CDS             complement(38297..38503)
                     /locus_tag="VXE01_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV0749700.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            38555..39031
                     /locus_tag="VXE01_000742"
     CDS             38555..39031
                     /locus_tag="VXE01_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV0749701.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            39040..39711
                     /locus_tag="VXE01_000743"
     CDS             39040..39711
                     /locus_tag="VXE01_000743"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV0749702.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            39842..40180
                     /locus_tag="VXE01_000744"
     CDS             39842..40180
                     /locus_tag="VXE01_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV0749703.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            40183..40812
                     /locus_tag="VXE01_000745"
     CDS             40183..40812
                     /locus_tag="VXE01_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV0749704.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            41052..42203
                     /locus_tag="VXE01_000746"
     CDS             41052..42203
                     /locus_tag="VXE01_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0749705.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            42516..43265
                     /gene="truA"
                     /locus_tag="VXE01_000747"
     CDS             42516..43265
                     /gene="truA"
                     /locus_tag="VXE01_000747"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV0749706.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            43255..44028
                     /locus_tag="VXE01_000748"
     CDS             43255..44028
                     /locus_tag="VXE01_000748"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0749707.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVDVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKRGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            44006..44467
                     /locus_tag="VXE01_000749"
     CDS             44006..44467
                     /locus_tag="VXE01_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0749708.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKRKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            44694..>44841
                     /locus_tag="VXE01_000750"
     CDS             44694..>44841
                     /locus_tag="VXE01_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0749709.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNIRYMIKLIDR
                     YGIEF"
BASE COUNT        13180 a         8195 c        10017 g        13449 t
ORIGIN      
        1 taatttttga aaaaattaaa ataataactg aaaaatagat tctaaagata actttcagga
       61 taaatttcta aattataaaa cgcatagtat caagtgtaaa aaacttggaa ttatgcgttt
      121 tatcatggaa agatttttta taatagctaa aaaataatag ttaaatggtt attaattgca
      181 ttccctagtg atttttgtta agataaatgc aaatacaaat gaaagcgaga acaagatgac
      241 acgttatcaa gatgattttt atgatgctat caatggagaa tggcaacaga cagctgaaat
      301 cccagcagat aagtctcaaa caggaggttt tgttgattta gaccaggaaa ttgaagacct
      361 gatgctggcg acaacagaca agtggttagc aggtgaagaa gtgcctgagg atgctatctt
      421 ggaaaacttt gtcaaatacc accgcctagt tcgtgatttt gacaagagag aagctgacgg
      481 tatcacacct gtcttaccac tccttaaaga attccaagaa ttggagactt ttgcggattt
      541 tacagctaaa ctagcagagt ttgagcttgc aggaaaacca aacttccttc cttttggtgt
      601 atcgccagac tttatggatg ctagaatcaa tgttctatgg gctagcgctc caagcacaat
      661 cttgccagat acgacctact atgcagaaga acatcctcag cgcgaagagc tcttgactct
      721 ttggaaagaa agcagcgcaa atctcctcaa ggcttatgat ttctctgatg aagaaattga
      781 agacttgcta gaaaaaagac ttgaattgga ccgccgagtt gcggcagtgg tgctctctaa
      841 tgaagaaagt tcagaatatg ctaaactcta tcatccatat tcttacgaag atttcaagaa
      901 attcgcgcct gccctacctt tggatgactt cttcaaagca gttattgggc aattaccaga
      961 caaggttatt gtagacgagg aacgtttctg gcaagcagca gagcaattct acagtgagga
     1021 agcctggtct ctccttaaag caaccttgat tttgagtgtt gtcaatcttt caaccagcta
     1081 tttaacagag gatatccgtg ttttgtctgg tgcctacagc cgtgcccttt ctggagttcc
     1141 agaggcaaaa gataaggtca aagcagctta tcatctagca caagaacctt tcaagcaagc
     1201 cctgggtctt tggtacgccc gtgagaagtt ctctccagaa gccaaggcgg atgtggagaa
     1261 aaaagtggca accatgattg atgtttataa ggagcgtctg cttaagaatg actggctcac
     1321 tccagaaacc tgtaaacagg ctatcgtgaa gctcaatgtg atcaaacctt atattggcta
     1381 tccagaagaa ttgcctgcac gttacaagga taaggtagtg aatgaaactg ccagtctttt
     1441 tgagaatgct ctagcctttg cgcgtgtgga aatcaagcac agttggagta agtggaacca
     1501 gcctgtagat tataaggaat ggggcatgcc tgctcatatg gtcaatgcct actacaatcc
     1561 tcagaagaac ctgattgtct ttccagcggc cattttacag gcgcctttct atgacttgca
     1621 tcagtcatct tctgctaact acggtggtat tggggcagtg attgcccatg aaatttccca
     1681 cgcctttgat actaacgggg cttcctttga cgaaaatggt agcctcaagg attggtggac
     1741 agagagcgac tatgctgcct tcaaggagaa aacacaaaaa gtcattgacc aatttgatgg
     1801 acaggattct tatggagcaa ccattaacgg taaattgact gtatcagaaa acgtggctga
     1861 cttgggagga atcgcagcag cgcttgaagc agctaagaga gaagcagact tctcagcaga
     1921 agagttcttc tacaacttcg gtcgcatctg gcgcatgaaa ggtcgaccag aatttatgaa
     1981 acttttggct agcgtcgatg tgcacgcacc agccaaactc cgtgtcaatg tgcaagtacc
     2041 aaacttcgac gatttcttta caacctatga tgtcaaagaa ggagacggaa tgtggcgttc
     2101 accagaggag cgcgtgatta tttggtaatg caaaaaatct agtcatcaga aaaaaggcat
     2161 ccaatcatgt gtgaaaacct tgataggatg ccttttgtaa tagaaagatt tgctggatag
     2221 tttacttaaa tttcgattgt catcatcttg ctagaaaaag ggattgaagg ccttttcgtg
     2281 agcgatagta gtagctggac catgtcctgg atagacatcg tagtttggta gggtgaagag
     2341 ttgggtctgg atactatgaa ggagttgctc catgctacca gtcggaaggt cggtccgtcc
     2401 gatagtttcg cggaatagag catctcccgt caagactaga tgagcatcag gaaagactag
     2461 ggaaacacca ccgatagagt gccctggggt cggtagaacc ttaaaacgaa attcctctag
     2521 ttggtattct tcgtgaaaga caaaggtgtg ttctgcaggt tttgtgacca catctgccat
     2581 atcatcgtgg cgagggagac cggagagatt atcgacagga gtgtagagcc agctggcttc
     2641 gctctctgcg atatagacag gaggattgcc aaacgtctcg cgaaccaagt ccagactcat
     2701 gatatggtca taatgggcgt gggtcaagag aatagcacag atcggtttgt tgatcttctc
     2761 gattgtctga cgaatggctt cccaatgact accaggatcg acgacgatga ggtgcttttc
     2821 gccttctaga taataggtat tttcataggc aacaggattc acggttttat ggattttcat
     2881 actagctcca atctcaaaga atgtactaat actcttcgaa aatctcttca aaccgcgtca
     2941 actttatctg caacctcaaa gcagtgcttt gaacagcctg cggctagctt tctagtttgc
     3001 tctttgattt tcattgagta taaattaagt atagcacagt tagggagaat aggtaaggat
     3061 ttaaaatgaa cttaaaaacc agcatgacta gatgaagaca ggctggttat caatttatca
     3121 atattggaaa ggtgtcaatt gcccttcata ggttgcataa actccgtcat tagcttgttt
     3181 gatagacgtg atgtttagag tgctaccgta gttggcttct catttgtcgc tatattcact
     3241 ataagttatc ctactgggca ggttctggtc gttagcatag tattgaacga ctgtttttta
     3301 tagctttgct ggctgaatag gaacaggcag caaactccta acattaggag agcaaagata
     3361 gaaatagcag tttttttcat aggtattctc cttataaact aaaggataga agaaagtatc
     3421 ttgaggattt ttatactctt caaaaatctc ttcaaaccgc gtcaacttta tctgcaacct
     3481 caaagcggtg ctttgagtaa cctgcggcta gtttcctagt ttgctctttg attttcattt
     3541 agtattaatt ccaaaatcca gtcaaggtac cagtgtatgt gatacgagtt ccaccgttta
     3601 tctttcgtat cttcaatgga attggggaag tcagaaagtc tttgggttac aatatggttt
     3661 ccgttcttct atctctcctt ctatcaccta agtttaaaat ctaacttcgt agtatattac
     3721 ggaccaataa ttcagaatta tcaagcaatt ttgaattatt tttttcttat tctgttccaa
     3781 tctagttttc atattcttaa aaaagtgata aaatggtagg aagaattgga gagtagagat
     3841 gccgaaagaa gtgaatttaa caggcgaaga agttgtcgct ttaaccaaag aatatttaac
     3901 ggaagaggat gttcattttg tccataaggc cttggtctat gctgttgaat gccacagtgg
     3961 tcaatatcgc aaatcaggcg agccttatat cattcaccct atccaagtgg caggtatttt
     4021 agctaagcta aagctggatg ctgtaacagt agcttgtgga ttcttgcatg atgtggtgga
     4081 agatacagat gcgactttgg acgatttgga aagagagttt ggtcctgatg tgcggatgat
     4141 tgttgacgga gttaccaagc ttggcaaggt cgagtacaaa tcgatcgagg agcaattagc
     4201 ggaaaatcat cgcaagatgc tcatggccat gtctgaggac atccgcgtta ttttggtcaa
     4261 actgtctgac cgcttgcaca atatgcggac cctgaaacat cttcgaaaag acaagcagga
     4321 gcgtatttcc aaagaaacca tggaaatcta tgccccgctt gcccatcgtt tggggatttc
     4381 cagtgtcaaa tgggaattag aagacttgtc tttccgttat ctcaatccaa cggagtttta
     4441 caagattacc catatgatga aggaaaagcg cagggagcgt gaggccttgg tggatgaggt
     4501 agtcacaaaa ttagaggagt atacgacaga acgtcacttg aaagggaaga tttatggtcg
     4561 tcccaagcat atttactcaa ttttccgcaa aatgcaggac aagagaaaac ggtttgagga
     4621 aatctatgat ctgattgcta ttcgttgtat tttagatacc caaagtgatg tttatgccat
     4681 gcttggttac gtgcatgaat tttggaaacc gatgccaggt cgcttcaaag actatatcgc
     4741 caaccgcaag gccaatggtt atcagtctat ccatacgact gtttatggac caaaagggcc
     4801 gattgaattc cagattcgaa ccaaggaaat gcacgaggtg gctgagtacg gggttgcggc
     4861 tcactgggct tataagaaag gtataaaggg gcaagttaac agcaaggaat cagctattgg
     4921 aatgaactgg atcaaggaga tgatggagct ccaagaccag gctgatgatg ctaaggaatt
     4981 tgtggactct gttaaggaaa actatttggc tgaggagatt tacgttttta ccccagatgg
     5041 agctgtccgt tcccttccca aagattcagg accgattgat tttgcctacg aaatccatac
     5101 caaggtcggt gaaaaagcaa ctggtgccaa ggtcaatggc cgcatggttc cactgacaac
     5161 caagttaaag acaggggatc aggttgaaat tatcgccaac ccgaactcct ttggacctag
     5221 ccgtgactgg ctcaatatgg tcaagactag caaggcgcgc aataagattc gccagttctt
     5281 taaaaaccaa gataaggaat tgtctgtcaa caagggtcgt gagatgctga tggctcagtt
     5341 ccaagaaaat ggctatgtgg caaataaatt tatggacaag cgccacatgg atcaagttct
     5401 gcaaaagacc agttacaaga cagaagactc cctctttgcg gccattggtt ttggggaaat
     5461 cggtgcgatt accgtcttta accgtctgac tgaaaaggaa cgccgtgagg aagagcgtgc
     5521 caaggccaaa gctgaggcag aggagcttgt caaaggtggc gaggtcaagg ttgaaaataa
     5581 agaaaccctc aaggtcaagc atgagggggg agtggttatt gaaggtgctt ctggtctcct
     5641 agtgcggatt gctaagtgtt gtaaccccgt gcctggtgac gatattgttg gctacattac
     5701 caagggtcgt ggtgtggcta ttcaccgtgt ggactgtatg aacctgcgtg cccaagaaaa
     5761 ctacgagcaa cgtctccttg atgtggaatg ggaagaccag taccctagct caaataagga
     5821 gtatatggcc catatcgata tctacggtct caaccgtaca ggactgttga acgatgtact
     5881 gcaagttctt tcaaatacaa ccaagaatat ttcaacggtc aatgcccaac caaccaagga
     5941 tatgaagttt gctaatatcc atgtgtcctt cggtattgcc aacctctcta cactgaccac
     6001 ggttgtcgat aaaattaaga gtgtgccaga agtttactct gtcaaacgga ccaacggcta
     6061 gttgtcctag ctcttactag aaaggctatt atgaaaatca ttatccaacg ggttaaaaaa
     6121 gcccaagtga gtatagaagg ccagattcag ggaaaaatca atcagggact tttattgctg
     6181 gttggtgttg gaccagagga ccaagaggaa gatttggact atgctgtgag aaaactggtc
     6241 aatatgcgga ttttttcaga cgcagaaggc aagatgaacc tgtctgtcaa agatattgaa
     6301 ggagaaatcc tctctatttc tcagtttacc ctctttgcgg atactaagag aggcaatcgt
     6361 ccagccttta caggggcagc taaacctgat atggcatcag acttctatga tgctttcaat
     6421 caaaaattag cgcaagaagt gcccgttcag acaggcatct ttggagcaga tatgcaggtt
     6481 gagctggtta ataatggacc tgttaccatt atcctagata ctaaaaagag ataagaaaga
     6541 ccaagcccag tcggcttggt ctttctcatc tatcataaaa tactccaaaa agaaatcggt
     6601 tcttgatatg cttgggggaa gtctcttttc aggctttggc agatgcgata ggaagggatg
     6661 agatgtccta ggatgaggag agttccctga aggaaaagtg gaatatcact taaagacacc
     6721 aaggagagaa tcatcaggct atcccatagg agaatttgta aagcaaaacg ccagaatctc
     6781 ggtctaatct gggaatagag ttaactaaag tggtcacaaa gttggtttga aagataggtc
     6841 aatagcacag gatgaaagaa aatgagccaa ccgctataaa tcaaaatcca gtcccaagta
     6901 agcccccttt taaatgtcaa aaatgccagc atgattccat caatgacaag gagttgaatg
     6961 gttttgatga agatgatttt tttcatgcta aaacctcctt ttccttagag acactcccat
     7021 aaagagatgt gtttgtcgta aaagtctgga tagttttctc ttaggtagtc agctgtcata
     7081 taataaaaag tagaatggca agcagtgatg attggcataa gagatgaaaa acgctgagaa
     7141 ctaatgaagg ctaagagaac aaaaaataga aaatcaatgg tgagaacccc taaatagtag
     7201 aagcgaatct ttttattgat ttgaggataa atctcagcga attgatgttt gagtcggacg
     7261 accaagagaa atagcaggag tccttgagca aggaagaaaa ttaaaccaga gagcaagagc
     7321 cactcaaaag atgtctcgag tctagtgata aaaaatgcaa atagtagcaa atcaataact
     7381 gcaattgcta taaaatggat tctatagagt tttttcatga caagacctcc ctcttttatc
     7441 taacttcatt ctactccaaa agaatgggag ttacaactaa aatgataaaa atagcagaag
     7501 ggagattctc ttaagttggc tagtattctt tatttgagtt tccttctatt atctaacttc
     7561 ttcatcattc cagacaaata aagctccgat tgcattgagg atataaaaga tgtatttacc
     7621 gatattggcg aagtttcctt gaataccagc ttttgtcagc tgaacgaaat tgtaaatcaa
     7681 ccaaaagccc cactgagttg ttagttttaa tgcattcaaa gcattggcaa tgagggacag
     7741 tgcaaaggca atagttgtta cgtaggcaag gagattcatc ttgcccccat atccgatata
     7801 gttggtcaca aaggcaaaga ggaaggcgat gatggaaatg atgatggccg ccaattttac
     7861 ctgtttttgg ctcatttggt tgggtctgcc ttcttgcgaa gcttcccact tctttatagc
     7921 aaaggtataa atgaggaagg tgacgggata ggtaatgatg gccgccttat ttccaaggat
     7981 ataatcaata gcaccggaca aaatggtatt aacaatacca aagtaatttc cccatttgct
     8041 taatttcccc gtgaaacgag tggacaacat ggaaatccca acgttggtta cggaaatcaa
     8101 tccaaagggt acaagagctg tccatgatcc ccagtctaca aatttatcga ggtgtgagtt
     8161 gaggtaacca gatgcaatcg caatcccaac gaccaaagca accccgaaga ggtcaaacta
     8221 tttagatgta gcaaaaattt ttagtgattt tttcataggt taaactacct ttcttttttt
     8281 caaatattct cccaccaaat gaaagtaaaa taaaatgata gaaataaaac cctgaaaata
     8341 aaactttcag ggttggtagg ggacttgaga aattagttga ttttctcgac atagagttgt
     8401 tttgcaatgt ccatattcac ttgtaaatcc tcgtcgttac tgaggatagt gaaggtattg
     8461 ctgaagccat caaactgctt gacttggagc tggtcaccga tgtgaagtga gtgcttgtcc
     8521 agataatgga gaatgtcaaa actatcgtgc acccgagtca ggcggtaggc gccagcttcc
     8581 ttgatatcag ctagtgggag gttattgatt tcaacgagta gttctccctt ggcaggaata
     8641 gttcctccgt gggggcaggt tttagggaaa cctagcagtt tatctagtct ttccacgaac
     8701 aggtcagaga cagtgtgttc caagacctca gcttcctcgt gaatctggtc acttgtatag
     8761 tctaaatgat gaactagaaa aacttcaatc aagcggtgct tacgatagag ctcagagacc
     8821 agtttgagac cgaggtcagt cagtagatag ccacattcct tgtcctttag gatgagattt
     8881 tcacttttca ttcgtttgat catttcagtt acggcagggg gagagacttg catgcgagcc
     8941 gcaatttcct tgttggtaat cttatgcagg tctatgccaa tttcataaat acattttaga
     9001 tagtcttctt tgtttggggt cattcgtttc ctcttgtcta atatctttat ctagtatatc
     9061 aaaaaaagct agatttctct agctgtgact ttttatgtta tacttattgc aagagaaaaa
     9121 acgaggagat ggatatgacg aaaatagctc ttctttcaga tattcatgga aataccaccg
     9181 ccttggaggc tgttttggca gatgctcagc agctaggagt ggatgaatac tggcttttgg
     9241 gagatattct catgccaggg acaggacgta gaaggatttt ggacttgttg gatcaactac
     9301 cgattacggc tagagttttg ggaaactggg aagacagtct ttggcatggt gtccgtaagg
     9361 aattggacag tactcgcccc agtcaacgct atctcttgcg ccagtgtcag tatgttttag
     9421 aggaaatttc cctagaagaa attgaagtgc tccacaatca acctcttcaa attcatcgtc
     9481 agtttgggga tttgacggtg ggaattagcc atcatctgcc tgataagaac tgggggcgag
     9541 agttgattca tactggcaaa caagaggagt ttgaccgctt ggtgactcat cctccctgtg
     9601 atattgctgt ttatggacat attcaccagc agttgcttcg ttacgggact ggtgggcaat
     9661 tgattgtcaa tccgggttcg attggccaac ctttcttttt ggacgctcag ctacggaagg
     9721 acttgcgggc ccagtatatg attttggagt ttgatgacaa aggcctggta gatatggact
     9781 tccgacgggt agactacgat gtggcagcgg aattgcagct ggctaaagac ctgagacttc
     9841 cctattttga ggtttactat gaaagtctgg tcaatgggat ccaccatact catcatcagg
     9901 aatttttgag agaattggct cagaaagagg gctgcgaccg ggagttagac gactggttga
     9961 aaagtggtaa cgattgacat tacaactaaa aagggtataa taatagaaaa agaagagtag
    10021 aggcagggta gcctcgtaaa aaggagaaga ggatgcaaat tccaagtaga tttaccattg
    10081 cgactcatat gctgataatc attgccctcg aggggaagga aagcaaggtg accagtgatt
    10141 ttctggctgc tagtgtcggg gtcaatcctg tcattatcag aaagatcttg tcccagttga
    10201 agaaggcaga gctgatttca gtagcgcgtg gaacgggcgg aacagagatt gtcaaggacc
    10261 ttaaggatat tagtctttta gatgtttatc aggcggtcga atgtcttggt aagacaggtc
    10321 aactcttcag tttccatgac aatccgaatc caaattgccc tgtaggagct catattcatg
    10381 atgttttgga tcaaaaattg gagagaattc agttgactat ggaggcagaa cttggtcaaa
    10441 ccagtctaga aaaagtcgtg gccgatgcag agagtcagat gaaggattaa gagggataaa
    10501 tgccctcttt tttctttgga taattatgat aaaatgtagc tattaaagga gtaagaaatg
    10561 tatctcgtta taggaattgt attagccttt atagtgtcat tttggaagga taatagaagt
    10621 ttgtggaatc cagtattatt tttattatcc ctcatttcaa gttattttta tctatcctac
    10681 cttttttata aaaatggata cgagaatgtt cagttagctt tttatgtatt tgcctttgtc
    10741 ttacttcctt ttttgctttt tctaagtggc atctttttaa tctataatgg ggtcattttg
    10801 ttgaagcgag agggacgttc caagccccat tatctctcaa tgctatttga tttttattga
    10861 ctattagatt ctatttaaaa agacttagaa tgcacatgaa agtatgtatt ctaggtcttt
    10921 tgttttgtat acatttaatt ttcaagagta ttatctattt ttccatgcct ggtaacgagt
    10981 atcaatcaat aactgggtaa ggcgacccaa ggtttctctt tcttctggag tgagggattg
    11041 agcttggaca aagagatgat gaatgtattc aagcgccttt aaggaagcca agtcattgat
    11101 agagctaata ccagcctcaa gaatagtgcc aaagaagagg tcgaagtaga gctgaagttc
    11161 ttcgtcaggg actgtggcca cccattcttt aaaggttgtg tctacttgct ggctatcact
    11221 gttggtctta tccagttgga cgaagtgctt atcctcaatc tgccaactaa aggtatcgtg
    11281 ctgggcgatg ccacccaggg cagtactctg aacgatgatt tggtgagcag gaatttccag
    11341 catcataccg ataatggaac cttgtggaat gaatatcttg cttctatcca ttatcctttg
    11401 ataacccgca gtctgtgtca attcttgatg gagaccaggt gcatcaaatg tataaactgc
    11461 tgtgatctga ttttgcaaac tttgctcaat ttggctagca gcatagatag cgagatttcc
    11521 tcccttggaa tgcccagcta gaataacctt ttgcttagga tgatgggcaa aaaagttctt
    11581 taaatagcga agggcgtgct tttgagcagg aatttccttc atataggtca ggtggaaatc
    11641 ttccttccag ccaatgatac tgtcatctgt cccacgaaag acaatcagat aggtatcgag
    11701 gctgacacga taagtcatag ccgcaaattg cttttgcagt tcagggtcga tgtcgttgat
    11761 aaaatgggag agtttgcaat ttttgaagcg cttgtgttga gccaattcat ctaataattg
    11821 aaggcgattt ttgctagtaa gcatggtggg atctcttgga acctgaggtg ctagatctaa
    11881 aagacgttga ggaagtgtgg agaccagatt atcaaaggag aggtaggtga tttctattaa
    11941 ggttagaatg tctaactcat tcaagggaag gtcgtaataa gaatcatatg cgacatcttt
    12001 cagatagtca aaaatattgg ccataagagc tcctttcttt ttatttatct tagcaaattt
    12061 ccctcaaatt agctagtagc attgcctgtt tgtactggct aaaaacaggc tatttcaaat
    12121 tcagtttcag accatctggc atggaaaaat ctgttataat aatagaaaag gagaagcgca
    12181 tgcacaagat tttattaata gaagatgatc aggtcattcg tcaacaggtc gggaaaatgc
    12241 tctctgaatg gggatttgaa gtggtcctgg tagaagactt tatgaaagtt ttgagtctat
    12301 ttgttcagtc ggaacctcat ctggtcctca tggatattgg tttgcccttg tttaatggtt
    12361 atcactggtg tcaggaaatc cgcaagattt ccaaggtacc tatcatgttt ctttcttcga
    12421 gagaccaggc tatggatatt gtcatggcaa tcaatatggg ggcggatgac tttgtgacca
    12481 agccttttga ccagcaggtt cttttagcta aggttcaggg cttgttgcgt cgttcctatg
    12541 agtttgggcg tgatgagagt ttgctggaat atgctggtgt tatcctcaat accaaatcca
    12601 tggatttaca ttatcaaggg caagtcttga atttgaccaa gaatgaattc cagattttac
    12661 gcgtgttatt tgagcatgca ggcaacatcg tagcacgtga cgacctgatg cgggaacttt
    12721 ggaacagtga ctttttcatt gatgataata ccctctctgt caatgtggct cgtttgcgta
    12781 aaaagttgga ggagcaggga ttggtaggat ttatcgagac caagaaagga atagggtacg
    12841 gattgaagca tgcttgattg gaaacaattt tttctagcct atctgcgctc ccgtagtcgt
    12901 ctttttatct atctgctttc tttggcattt cttgtcttac tctttcagtt tttatttgcc
    12961 agtctaggaa tttacttcct ctactttttc ttcttgtgtt gctttgtaac catattattt
    13021 ttcacttggg acatattggt ggaaacgcag gtctatcgcc aggaacttct ctatggagag
    13081 agggaagcca agtctccttt ggaaatagct ttagcagaaa aattagaagc gcgtgagatg
    13141 gaactctatc agcagaggtc aaaagcagaa agaaaactga cggatttgct ggattactat
    13201 accttgtggg tccatcagat aaagaccccc attgcagcca gtcaactctt agttgcagaa
    13261 gtggtcgacc gccaactgaa gcagcagcta gaacaggaaa ttttcaaaat cgactcctat
    13321 accaacctag ttttacagta cctgcgttta gaaagtttcc atgatgattt gctcttaaag
    13381 caggttcaaa ttgaggactt ggtcaaggaa ataattcgta aatatgctct tttctttatt
    13441 caaaaaggct taaatgtcaa tctacatgac cttgataaag aaatcgtgac ggataaaaag
    13501 tggctgctag tggttattga gcaaatcatc tcaaacagtc tcaagtacac caaggaaggt
    13561 ggtctggaga tttatatgga tgaccaagag ctttgtatca aagatacggg aatcgggata
    13621 aaaaacagtg atgtcctccg agtatttgaa cgtggctttt caggatacaa tggccgtttg
    13681 acccagcagt cctctggact tggcctttat ctatctaaga aaatttctga agaactgggg
    13741 caccagattc gtatcgagtc tgaggtcgga aaaggaacga cagtgcggat tcagtttgct
    13801 caagtgaact tagtccttga gtaaaaatag atgagaaaaa gcctccagat tggaggcttt
    13861 tatgctagac tcttatttct caacgcgtga tttgttggcg atatcagcta ggatagcttg
    13921 aacaaaatta tcaactgaga cagtttgtgt ttctttttgg ccgtagcgac gaacgttgac
    13981 tgtttcgtct tccatttctt tgtctccaac aattaattgg taaggaatct tgctggtttg
    14041 tgaagcacgg atcttgaact gcattttttc attgcgctca tctacgtctg cacggacacc
    14101 gcggtcacgg agtttcttgg ccacttccca agcgtagtcc acgtgttttt cgttagatac
    14161 tgggatgagg gttacttggt gtggtgccag ccatgttggg aaggccccct tgtagttctc
    14221 aatcaagata gctgtgaagc gttccatagt tgagataact ccacggtgga tcatgactgg
    14281 acggtgatct tcgccatcag ctccgatgta tttgaggtcg aagcgttctg gtaacaaaaa
    14341 atcaagttgg atagtagaaa gggtttcttc ttttccaagg gcagttttaa tctggatatc
    14401 caattttggt ccgtagaagg ctgcttcacc ttcggcttca aagtagtcca cgcccatttc
    14461 atcaagagct gcacgaagca tggtttgggc attttcccac atctcatcgt tatcaaagta
    14521 cttatgagta tcttgagggt cacgaagaga gaggcggaag cggtagtcag tcaagttgaa
    14581 gtcttcataa acatcgataa tcaactgaag ggcacgttgg aattcttctt ggatttgttc
    14641 tggagtaacg aataggtgac cgtcgttgag tgacatttca cgtacacgtt gaaggccagt
    14701 gagggcacca gatttttcgt aacggtgcat cataccgatt tcagcgatac ggattggcaa
    14761 ttcacggtaa gagtgaacat ggtgtttaaa aacttggatg tggtgcggac agttcattgg
    14821 acgaaggaca aattcttccc cgtcacccat gtccatggtt gggaacatgt cttcttggta
    14881 atgatcccag tgaccagaag tcttgtaaag ctcaacagaa gcaagtggtg gagtgtagac
    14941 gtgttggtag ccagaagcca actctttgtt tacgatgtag cgttccaatt cacgacggat
    15001 agtcgcacca tttggcaacc agaatggcaa accttgtccc acttcttgtg aaatcataaa
    15061 gaggtcaagc tctttaccaa gtttacggtg gtcacgttcc ttagcttctt cacgcatttg
    15121 aaggtagttt ttcaagtctt tcttgtcaaa ccaagctgta ccgtagatac gttgcatcat
    15181 agcgttgtcg ctgtttccac gccagtacgc accagctaca tggagaaggt ggaagatttg
    15241 gatacgacct gttgatggaa cgtgaggtcc acggcagagg tctacatatt caccctgacg
    15301 atagatagtc aaaccgcctt cgtcttctga gtgttcttca atcaattcca acttgtaagg
    15361 gtcatttttg aagatttcac gtgcctcgtc tttagtcact tcttcacgaa tagatgggaa
    15421 gttttctttg acgatttttt gcatttcttc ttcgatacga ggaaggtctt cgttagagat
    15481 ttgaccagct gtgttgtcag tatcgtagta gaaaccatct tcgatggctg gaccaactcc
    15541 caagtgaatg tctgggaaaa gacgacgagc tgcttgggcg aacaagtgag ctgctgagtg
    15601 acgcaagatt ggaagggcat cttcgtgatc aggtgtcaca atttcgatgc ttccatcttc
    15661 agtgatagcg cgagtagtgt cgatgagttt gccgttgaat ttaccagcca aggctttttt
    15721 agctagggaa ttgctgatag attgggcaat ttcaaaagtt gttacgccag attcgaattc
    15781 acgaacagcg ccatctggga aagtaatgtt aatcatgatg ttctcctttt ttattatttc
    15841 atagtttcta agcattgatt ttttatcagc agactacttc caagtcctaa cgttcaattg
    15901 cttttcttta tcagagagga agttttccat ttccgtcaga atgtctatat ccaaacgttg
    15961 agaaagttct aatagccacc agatattttc tgaaagtttt tgttccagtg tgtagggtgt
    16021 ttcatcatag tagcgtcctt gctttgtcat caccagtcgt tggaaatttc caatatcatt
    16081 agataaagcc aagaggtctt cttctaccgt ccacttggaa tcatgatgct taacttccag
    16141 ttcgtgataa gtttgtcgga ttgcccaact gcgctccact aattcttgca actccataat
    16201 tagtatccta ataaaaaaat gcgacatcct cgaaaggacg tcgcaacgtg gttccacctt
    16261 catttatgta cctcaaaaga gagggacacc tctgatcggc tctaacgtgg ccaccgtttt
    16321 atgttttcat aaaaaactca agagtagtat cagtttagac ttcctatgcg tttccagcaa
    16381 ccacgcactc tctagtagaa agggactaag tgacttgtct ctatggatta ttatagcatg
    16441 attgtgagat ttttcaagga ttttgtgaaa gttttttgtt tttcattttt tgtagaatat
    16501 gcttgatgct aataccagaa tccatgccca ccagagcaac tgtttcatag attagcaagt
    16561 aaattagtat aaactcacca aaggttatga tagtaaagta aaagagcagt ccgttaccaa
    16621 ctaaccatca aagtgagaaa cggaaacggt agctatagag taacgatata atcaagatta
    16681 ccagaggtgt aaagaagaga agattgttta tatagagttc cttgagtgta agggggtcag
    16741 aaacaactag taagaacaac tcataaagtg gccaataaaa gaataatatg accagatagt
    16801 aggggagatg ggaatagaat ctacgcatga taatcacctc gttttaaaaa aacagacaac
    16861 ttagatctct tgctatgatt attatagcat gtttaaaaca agaaagtaaa tttgttgaca
    16921 aagaagattt ttcttttcac tagaatcata gttagttttc ttggtagaaa tattttgata
    16981 ataattaagc aagactattg acattgatta ttaagagtgt cacaattatt gtaactaaaa
    17041 taattacaac aagagaggta taaaaaatga aactagcagt tattgcagca aatggacaag
    17101 cggggaaagc aattgttgaa gaagcagtca aacgaggaca tgaagtaacg gctattgttc
    17161 gttctgaaaa caaaagtcaa gctgagtcta ttattaaaaa agatttattt gagttgacaa
    17221 aagatgatct tactggattt gatgctgtta tttcagcgtt tggtgcttat acaccagata
    17281 cgctaccgct ccacagcaaa tcaatcgaac tatttaatca gcttcttgct ggaacacaga
    17341 cacgttttct agttgtaggg ggagcaggaa gtctttatat agatgaaaca aaaacgacac
    17401 gacttttaga tacgtctgat tttcctgaag aatttaagtc actagcaaaa gatcaagcgg
    17461 atgaattgga tcttcttcgt acaaaaaata atctcaactg gacttttgtc agtcctgctg
    17521 tagattttat tcccgatggt gaaaaaacag gaaactacat tctagcagga gaaattttta
    17581 ctactaatga aaaaggaata agccagatta gttatgcaga ttatgctatt ggattggtag
    17641 atgaacttga aaaaggtcat catataaaag aacgtatctc tttacttgaa aaataataac
    17701 tatgagagta ttaatgtttg acagaaaatt taaatcttga taaaataggg attgtcgtaa
    17761 agacaaataa cttcttcttg gttacaggca tgccaacctg tcactcggat gaagccaaat
    17821 aaaaaggaga aacatcatgg caatctcaaa agagaaaaaa aatgaaatca ttgcacaata
    17881 tgcacgtcac gaaggtgata caggttcagt agaggttcaa gttgctgtcc ttacttggga
    17941 aatcaaccac cttaacgaac acatcaaaca acacaaaaaa gaccacgcta cttaccgtgg
    18001 attgatgaaa aaaatcggtc gccgtcgtaa cttgcttgca tacttgcgta aaaacgacgt
    18061 taaccgttac cgtgaattga tcaactctct aggacttcgt cgctaattca agatacaaag
    18121 gccgtcaaaa gcacaaagca aaaataggaa aattgacgaa gaaacttcag tttctaggag
    18181 attttatctt ttttgccaag tgcttaggcc gtgttcaatt gagcatatct tgataataaa
    18241 gctactctaa attgggtagc ttttttgcgt tgtcacctta cctcgctata ctcaagtata
    18301 atcttcggtt acggttccta gcactgtaag gtaaaataaa ctagcttttc tcccttcggg
    18361 gagatttttt ttgtttcact gaaagtttcg tacgatcttc gcctcgtcgc ctagtctata
    18421 aacgatttat ctagcaagaa tcatgatgct aagggcgtca aaaatccgta tgaaaatagg
    18481 gaaatgacac agtgttcgat gagcacaagg agtttcatct ttttcactag gattttagcc
    18541 cgggctaaaa tcagctctct gacttcagag ggctttttta ttgaggtttt atcggtaaca
    18601 attttggaga ctacaaaaac ctcaaatggt atcagctaat tacaccataa aggtgcgcag
    18661 ttactcggct tttcaagccg agtagctgta tgcaagcccc ctagaagagc ccactcttta
    18721 caaagtaaag tatagtatgt tatactttac atggaagtag tcactgaatt ccagttagaa
    18781 attactttgt aactacgttt tgaggaggag taaaatgctt tcctacgttc gacattaccc
    18841 actagcgata gctaaattaa tgtgtctgtg ctctcctgaa atctgctgat ttattactga
    18901 ctaatacagg aggttttttt atgggacaga caatcatatc tgctattggt gtttatattt
    18961 ccaccagtat cgattattta attattttaa ttattttatt tgcacagcta tcacagaata
    19021 aacagaaatg gcatatttat gcggggcaat atctaggcac aggcttactt gtaggggcga
    19081 gtttagttgc tgcttatgtc gttaatttcg tgcctgaaga atggatggtt ggattgcttg
    19141 gtttaatccc tatctattta gggattcgct ttgcaattgt tggagaagat gcggaagaag
    19201 aagaggaaga aattattgaa agattagaac aaagcaaggc aaatcaactg ttttggacag
    19261 ttacattgct gacaattgcg tctggcggag ataatttagg tatctatata ccttattttg
    19321 cttcgttaga ttggtcacag accctcgtgg ccttgcttgt gtttgtaatc ggcataatta
    19381 tcttttgcga gattagtcgg gtgttatcct ctattccgtt aatattcgag acaattgaaa
    19441 aatacgagcg aatcattgtg cccttagtat tcattctact tggactatac atcatgtatg
    19501 aaaatggcac gatagagact tttctgatcg tgtagatttt tttgtttcac taggatttta
    19561 gcccgagctc aaatcagctc tctgattttc agagggcttt ttcattgagt ataaatggac
    19621 aatcttaaag ttactctatt gtagagtggc ttttgatttg attaggagat tcttataaat
    19681 atagtaaaat gaaacaaaaa caggacaaat cgatcaggac agtcaaatcg atttctaaaa
    19741 atgttttaag aagtagaggt gtactattct agtttcaatt tgatatataa atgaaaacct
    19801 tagctgtttg gccaaggttc atttcttcta tgcaagttct tctcttttct tatctgggtt
    19861 ccagatgaag cttgcgataa agctaaagat gatggttagg atagcgagga taatagcaag
    19921 gatgagggca gggatgcgga taaaccacca gagtggattt ggttttttat cattgtgcca
    19981 ttgtttcgtt tcttcgtcca gacgttggaa ttctgtttga atacgattgg cgactgtttc
    20041 aatgccttca tcattcattt tcttgatatc tgagatatcg attggatttc caaagttcat
    20101 atcgacacgt tcacggctaa tcaagccctt caaagtcatg ggaccggtgt aggtaaccgg
    20161 catgatacgg accttggcca ttttggcaat cagtgctgcg ccccccttga catcgtttga
    20221 gtggcggcta ccacttggaa acatgatgag agagcggtca ctttttttga gaacgttgat
    20281 aggatatttg atggctgagg cgctgggatt ttcacggtcg atgggaaagg cgccacacat
    20341 acgaatccac caaccaaaga tacggttggt aaagagttct ttttttgcca taaagatgaa
    20401 ctgttttggc ttggtcgcaa aggccatata aacaggatcc caccaggtac ggtgaggcgc
    20461 aactaaaata taattttcat cttgattagg aattttatca gtattatgat agtgagcatt
    20521 gccattgatg gaccataaga gcaatacaac taatccacgc aaataagtat aaaacatgcg
    20581 atctccttcg attgttttct tgttattatt ataccttatc aaaggagggc tggcaaactt
    20641 ttcccttgac tagatacata tttaggatga aattagaatt ctgttaaaaa aaatgatata
    20701 atagaattta tggataaaaa taagattatg ggattaaccc aaagagaagt caaggaaaga
    20761 caggctgagg gtttggtcaa tgactttacc gcatcagcca gtaccagcac ttggcaaatc
    20821 gttaaacgaa atgtctttac cctttttaac gctttgaact tagccattgc tttggctctt
    20881 gcctttgtgc aggcttggag caatctggtc ttctttgctg ttatctgctt taacgctttt
    20941 tctgggattg tgaccgagct acgagccaaa cacatggtgg acaagctcaa tctcatgacc
    21001 aaggaaaagg tcaaaaccat ccgtgatggt caggaagttg ctcttaatcc tgaagaatta
    21061 gtgctaggag atgtcattcg tttgtctgca ggagagcaga ttcctagtga tgccttggtt
    21121 ttggaaggct ttgcggaagt caatgaagcc atgttaacgg gagaaagtga tttggtgcaa
    21181 aaggaagttg acggcttact tttgtcagga agtttcctag ccagtgggtc agttttatct
    21241 caagttcacc atgtcggtgc agacaactat gctgccaaac tcatgcttga ggctaagacc
    21301 gttaaaccca tcaactcccg tatcatgaaa tcgctggaca agttggctgg ttttactggg
    21361 aagattatca ttccctttgg tctggctctc ttgctggaag ccttgctttt aaaaggcctg
    21421 cctctcaagt catctgttgt aaactcgtcg acagctcttt tgggaatgtt gcctaaggga
    21481 attgcccttt tgaccattac ttcgctcttg actgcagtta tcaagctagg tttgaaaaag
    21541 gtcttggtgc aggagatgta ctctgttgag accttggcgc gcgtggatat gctctgtctg
    21601 gacaagacgg gtaccatcac ccaaggaaag atgcaggtgg aggctgttct tccgttgacg
    21661 gaaacgtatg gtgaagaggc tattgccagc atcttgacta gctacatggc ccatagtgag
    21721 gataagaatc caactgccca agccattcgc cagcgttttg tgggagatgt tgcttatcct
    21781 atgatttcca atcttccctt ctccagcgac cgcaagtggg gggctatgga gttagaaggc
    21841 ttggggacag ttttcttagg ggcacctgag atgttgctgg attctgaagt cccagaagcc
    21901 agggaggcct tggagagagg atcacgtgtc ttggtcttag ctctcagtca ggagaaatta
    21961 gaccatcaca aaccacagaa accatctgat attcaggctc tagccttgct ggaaatcttg
    22021 gaccccattc gagagggagc agcagagacg ctggactatc tccgttctca ggaggtagga
    22081 ctcaagatta tctctggtga caatccagtt acggtgtcta gcattgccca gaaggctggt
    22141 tttgcggact atcacagcta tgtagattgc tcaaaaatca ccgatgagga attgatggcc
    22201 atggcggagg agacagctat tttcggacgt gtttcccctc atcaaaagaa actcatcatc
    22261 caaacgttga aaaaagcggg tcatacaacg gctatgacag gggacggggt taatgatatc
    22321 ttggcccttc gtgaggcgga ttgttctatc gtgatggcgg agggggatcc agcaacccgt
    22381 cagattgcca atctggttct cttgaactca gactttaatg atgttcctga gattctcttc
    22441 gagggtcgtc gcgtggtcaa taacattgcc cacatcgccc cgattttctt gataaagacc
    22501 atctattcct tcctgttagc agtcatctgt attgccagtg ctttactagg tcggtcagag
    22561 tggattttga ttttcccctt cattccgatc cagattacca tgattgacca gtttgtggaa
    22621 ggtttcccac cattcgttct gacttttgag cgaaatatca aacctgttga gcagaatttc
    22681 ctcagaaaat ccatgcttcg tgccctacca agcgctctca tggtcgtctt cagcgtcctg
    22741 tttgtgaaaa tgtttggcgc gagtcaaggt tggtctgagt tagaaatctc aactctactc
    22801 tattatctct tggggtcaat tggtttctta tccgtattta gagcctgcat gccatttacc
    22861 ctatggcgtg tcctcttgat tgtttggtca gtaggaggtt tcctagccac agctctcttc
    22921 ccaagaattc aaaaactgct tgaaatttca accttaacag aacaaacgtt gcctgtttat
    22981 ggtgtcatga tgttggtctt taccgtgatt ttcatcctga ccagtcgtta ccaagcgaaa
    23041 aaataaagaa agactgcaat ctgtggattg cagtttttta tacgatggat ctatcgtaga
    23101 tctgatgtgc aaggcctacg tgccgatcat ctatcggtga acccaagagc gaccctcaag
    23161 cctgcttgga ttgaggtaat agattcaaat atctgtagtt agactatttg aagtttgatg
    23221 taagaaagag aaagcgacag attgaagtaa ttttaactct cttctattgc tagaacaaat
    23281 ggtcggatag gttggtagtt tgaaaatgaa gatgctatct attgttaaat ggaacatagt
    23341 gttatttatt agaaaatcgt ttggtttatt tcttatcaaa tacgaaaagc aacttaaata
    23401 tttcaactaa aatagatgtt atgaagaaaa ggtaaaatga ttttggcata gtgaggttct
    23461 gttctatttg atatcatatt tttgataaaa acaaaaatgt ccattgcaaa ggacaaaatg
    23521 cgaagtatat tattttttga aagcgatata atggattcat aaaggaggtg tatcgtgtct
    23581 agaaaacaag aacaaatgga aacgttgttg ctccttttgc gagatagtaa ggattatata
    23641 tctgctaaag tattgggaga aaaattaaat tgctctgata aaacggttta tcgccttgtc
    23701 aagggaatca acaaagattg tccggtagaa gcattcattt tatctgaaaa aggcagaggt
    23761 ttcaaattaa atccaagaag ttccctcgtg gacgttgatg ggaattttac agaggctttt
    23821 gatcctgaag taaggcgtga aaaattacta gaacgtctct tgttgactgc tcctaagcca
    23881 cattctattt atgatttagg agaggaattc tacgtaagcg agtcagtagt actaaaagat
    23941 cgtcagatat tacaagagag tctagcaatt tatgggttag atttaaaaat gagacaacga
    24001 aagcttttta ttgatgggga tgaggctcaa attcgttcag ccattctaaa tctactgcca
    24061 atgtttaatc agttggattt agagcaaatt acacagaata aggttcagcc tcttgacgga
    24121 gaacttgctc acttttgttt gggattactg attacacttg agagagaatt gggggtaaac
    24181 attccctatc catataatat aaatattttc tctcacctgt atatttttat cagtaggaat
    24241 cgtcgtagta ctagtattca tgttgtagca ccttcaaaac ctactattgt tgatgagaaa
    24301 atttacagtg tctgtcaaaa aattattcaa gaaattgaac aatattttag gatgaaggtt
    24361 gatgcagttg agattgacta tctttatcaa tacgttgtat cttcgagatt gcaaaaacca
    24421 ttttcttccg ggaagcttcc tttttctcag cgagttttag atgtcactca ttactatttt
    24481 agccgtatgt gtatggacaa tagagagatt gaaacgacag atcctgactt tgttgacttg
    24541 gcgagtcata tcagtccctt actgaggaga ttagataata gagtacagat taagaatagt
    24601 cttttatcac aaattctttt aacctatcct aatctggtta aagagttaac aactatttct
    24661 aaagaagtga gtctagtatt tggttttgct tccttgagtc tggacgagat tggttttcta
    24721 gtcttatatt ttgcacggtt tcaagaaaag cgagcacgtc ctctaaaaac agtagtgatg
    24781 tgtacatcag gtgtcggaac ttcagagctt ttacgagcac gattagaaaa gcaattttct
    24841 gaattggata ttattgatgt agttgcttat catcaattag atgagctgat aaatctatat
    24901 ccagatttag atttcattgt gacgacggta gctttgcagg aaccagcaag tgtcccgttt
    24961 gtcctagtta gtgtttttct aaccgagggt gataaacaac gtcttcaagc aaaaattcag
    25021 gagataaact atgaataatc tttcgcttgt ccttatggat atatctgttc aaaatcgtca
    25081 agaagcctac aaagaattag caaatcaaat cagccttctt gtttctgaag atacagaaaa
    25141 aatagaagag cttctatatt accgtgagag acagggaagt atagaggttg ctaaaggtgt
    25201 tcttctacca cattgtgaag gaaactttca acatcatgtc ttagtgatta ctagattaaa
    25261 atcacctatc agagaatggt cgaaggatat ccagtgtgtt gaccttatta tcggtttggc
    25321 cattgcagta tcacaggaca agtcatgtat taaaacattg atgagaagac tagcagatga
    25381 atcattcata aatcaattaa aacagttaac aaaagaagaa ttacgggaga taatatatgg
    25441 aaatcaaaga tattcttaat gtgagtctga tccagacgga tttacagatg cagagcaaag
    25501 aagaggtttt tgaggcatta gctcaactat tggttgagac gggttatgtg tctgatagag
    25561 accaatttat cgaaggtctt tatcagagag aggcagaagg acagaccggt attgggaatt
    25621 atattgctat tccccatagc aagagttctg ctgtggagaa ggcgggggta gtcatagcta
    25681 taaatcacaa tgagattcct tgggagacca ttgatgggaa aggggtcaaa gtaattgtac
    25741 tctttgcagt tggtgatgat acagaagctg ctagggagca tttgaagacc ttatcactct
    25801 ttgctcgaaa acttggtaat gacgaagttg ttgccaaatt agttcgggct cagacatctg
    25861 atgatgtgat tgcagctttt tgttaataag aaaaaatttt ggagggtatc cgtatgaaaa
    25921 ttgttggtgt tgcagcttgt actgtgggaa ttgcccacac ttatattgca caggaaaaat
    25981 tagagaatgc cgcaaaggta gctggacatg tgattcatgt tgagactcag gggacaatag
    26041 gggtagaaaa tgaattgagt caagagcaga ttgatgcagc ggatgtagtt attttagcag
    26101 ttgatgttaa gatttctggt atggaacgct ttgagggtaa aaagattatc aaggttccaa
    26161 cagaagtggc agtcaaatct cccaataaac tgattgctaa agctgttgag attgttacga
    26221 aataactgaa aatatttaag gagaaaatat atgttgaaac acttaaactt aaaaggtcac
    26281 ttattgacag ccatttccta tatgattcca attgtttgtg gtgcaggatt cttagttgcc
    26341 attggtttag caatgggggg tggtgttcct gacgctcttg tagcaggaaa attcactatc
    26401 tgggatgctt tagcaactat gggtggtaaa gcccttggtc tcttgccagt tgttattgct
    26461 acaggtttgt cttactcgat tgctggtaag ccagggattg caccaggttt tgttgttggt
    26521 ctaattgcca attctgttgg ttcagggttt atcggtggta tcttgggagg ttatatagct
    26581 ggtttcttgg ttcaagcgat tattaaaaag gtcaaagtac caaactggat taaaggttta
    26641 atgccaacct tgattattcc ttttgtagcc tctttggtaa gtagtttgat tatgatttat
    26701 attattggag cgcctatcgc agcctttacc aactggttga cgagcttatt acaaagcttg
    26761 ggaagtgctt caaatggttt gatgggggca gttattggag ttctcagtgc tgttgacttt
    26821 ggtggcccac ttaataaaac agtctatgcc tttgtgttga ctttacaggc tgaaggtgtg
    26881 aaagaaccat tgactgcttt gcaattggtg aatactgcta caccagttgg atttggattg
    26941 gcctatttta tcgcgaaatt actcaaaaaa aatatctata ctcaagagga aatcgaaaca
    27001 ttgaaatcgg ctgttcctat ggggattgtc aatattgttg aaggtgtaat tccgattgtt
    27061 atgaataact tggttccagg tctcattgca acaggtatcg gtggtgctgt tggtggtgct
    27121 gtttctttga caatgggtgc tgattctgcc gtgccatttg gtggagtgct tatgttacca
    27181 accatgactc gtccagtagc tggtatttgt gctttgttag ccaacattgt agtcacagga
    27241 cttgtctacg cgattttgag aaaaccaata aaacatacag aaccagttat gactgttgaa
    27301 gaagagattg atttgtcaga tattgaaatt ttgtaagagg gtaacgatgt caagaattga
    27361 attttcacca tctttgatga ccatggattt ggacaaattc aaagagcaga ttactttttt
    27421 gaatgataaa gtagcatctt atcatatcga tattatggat ggccattttg ttcccaatat
    27481 taccttgtct ccttggttca ttcaagaagt tcaaaaaatt agtgacacac ctttatcagt
    27541 tcatctgatg gtcacagacc caaccttttg ggtagatcaa gttctcgatt tacaatgtga
    27601 gtatatttgt attcatgctg aagttctgaa tggtcttgct tttcgtttga ttgataaaat
    27661 tcatgatgca ggtctaaagg ctggtgttgt ccttaatcct gaaacacctg tttctacaat
    27721 ctttccctac attgatttac ttgacaaagt aactattatg actgtagatc caggttttgc
    27781 aggacaacgc tttttggagt ctaccttgta taaaatccaa gaactccgtc agcttagagt
    27841 tcagaatggt tatcactaca tcattgagat ggatggttct tcgagtcgta agactttcaa
    27901 acaaattgat gtggcaggac cagatattta tgttataggt cgcagtggat tatttggttt
    27961 ggatgacgat attgccaaag cctgggatat ctgttctaga gattacgaag aaatgaccgg
    28021 aaaaacaatg ccaatcaaat aatggtttga gaagaaattt attagttagg aggaatatat
    28081 gtcactacaa tcagttaacg ccattcgttt tcttggcgta gatgctatta acaaatctaa
    28141 ttctggtcac ccgggaatcg tcatgggtgc tgcgccaatg gcttatagcc tatttacaaa
    28201 gcaccttaga attacacctg agcagccaaa ctggattaac cgagatcgct ttatcttgtc
    28261 tgcgggtcat ggatcaatgc tactgtatgc tctcttgcat ttaacagggt ataaggatgt
    28321 atccatggac gagattaaaa atttccggca atggggatct aagacacctg gtcatcctga
    28381 agtgacgcat acgtctggtg tggatgcgac atctggtccg cttggtcagg ggatttctac
    28441 tgccgttggt ttcgcccaag cagagcgttt tttagctgct aagtacaaca aagatggttt
    28501 tcctattttt gaccattata cttatgttat cgctggagac ggtgacttca tggaaggagt
    28561 gtctgcggag gcggcttctt atgcaggtca tcaagcttta gataagctta tcgtcctcta
    28621 cgactccaac gatatctgct tggatggtga gaccaaagat actttctctg aaaatgttcg
    28681 cgcccgttac gatgcttatg gttggcatac agttctggta gaagatggaa cagatttagc
    28741 agcaatttct acagcaattg agacggccaa gttttctggt aagccgagtt tgattgaagt
    28801 gaaaacggta attggttacg gctcacccaa taaaagtggt acaaatgctg ttcatggtgc
    28861 accactagga gcagaagaaa caggagcaac tcgtaagttt ttgggatggg attacgatcc
    28921 atttgaagta ccagaggaag tatattctga tttcaagaca aatgtagcgg atcgtggtca
    28981 ggaggcatac gatgcttggg ctagtttggt gtctgattac aaggttgctt atcccgaagt
    29041 tgctagtgag attgacgcta ttgtagctgg aaaatcccct gtaaccatta ctgaaaaaga
    29101 cttccctgtc tatgagaatg gcttctctca agcaactcgt aattcgtccc aagatgctat
    29161 taatacagca gcagttttac caaccttctt aggtggatcg gcagacttag ctcactccaa
    29221 catgacctac atcaaggcag atggcttaca agataaatat aatccattaa accgcaatat
    29281 tcagtttggg gtacgtgaat ttgccatggg aacaatcctc aatggaatgg ctcttcatgg
    29341 tggtttacga gtttatggcg gaaccttctt tgttttctct gactacgtca aagctgctat
    29401 tcggctatca gccattcagg agttgcctgt aacttatgtc tttacccatg attcaattgc
    29461 cgttggtgaa gatggtccaa ctcatgaacc agttgaacat ttggcaggtt tacgctcaat
    29521 gccaaacttg actgttatcc gtccagcgga tgcccgtgaa actcaagcgg cttggcatca
    29581 tgccttgacc agtaccacca ctccaactgt cattgtctta acccgtcaaa acttggtagt
    29641 tgaagaaggg acagactttg gtaaggtcgc taaaggagcc tacgtcgtgt atgatacccc
    29701 gggatttgat actattatca ttgctacagg atctgaggtc aatctagcta tcaaagctgc
    29761 taaggaattg gttttacaag gtggtaaagt acgtgtggta tctatgccct caaccgaact
    29821 atttgatgct caagatgcta cctacaagga agacatttta ccatctaaga ctcgtcgtcg
    29881 tgtggccatt gaaatggcag cgacccaaag ttggtacaag tatgttggtt tggatggcgc
    29941 ggtcatcggt attgacatct tcggtgcgtc tgccccagct cagactgtga ttgataatta
    30001 tggatttacg gtagagaata tcgttgctca agttaagtcc ctatagaaac caattacaat
    30061 gaagatacag ctgttgtcag actagcagat gtagtgatag acactaatca gatgattggt
    30121 tatttaaaaa ctataatgag aatgtaataa tttatctacg aaagttataa tagatagtat
    30181 acacaataga gtatactctg aaacggttgc gaagtacgct aatcactttg ctactgatct
    30241 agatagtttc tttaatcaat aaacacagca tccacagatt gacttaggat attgtaagtt
    30301 ttttgaaagc tagagagaag gtctctaaaa ttaaaaaacg catagcatag gatgttaaaa
    30361 tgaactgacc ccaaaagtta gacagaaaaa atctaacttt tggggtgttt ttattatgaa
    30421 actaacttat gatgataaag ttcagatcta tgaacttaga aaacaaggat atagcttaga
    30481 gaagctttca aataaatttg ggataaacaa ttctaatctt aggtacatga ttaaattgat
    30541 tgatcgttac ggaatagagt tcggcaaaaa aggaaaaaat cgttactatt ctcctgattt
    30601 aaaacaagaa atgattaata aagtctgaca tgaaggctgg actaaagata gagtttctct
    30661 tgaatacggt ctcccaagtc gtacgatact tcttaactgg ctagcacaat acaggaaaaa
    30721 cgggtatact attgttgaga aaacaagagg gagagtacct aaaatgggac gtaagccaaa
    30781 aacgatacct gaagagagga cagaattaga acatcttcaa gcagaaaatg agtacctgag
    30841 agcggagaat gccatcctaa aaaagttaag agaactccga ttgaaggagg aaaaagagaa
    30901 agaagaaaga cagaaattgt tcaagaatta atgactgagt tttcgttaga tcttcttcta
    30961 aaagccatta aactagctcg ttggacctac tactatcact tgaaacagct agataaaaca
    31021 gataaggacc aagagcttaa agctgaaatt caatccattt ttatcgaaca caagggaaat
    31081 tatgcttatc gtcggattta tttagaacta agaaatcgtg gttatctggt aaatcataaa
    31141 agagttcaag gcttgataaa agtactcaat ttacaagcta aaatgcgaca aaaacgaaaa
    31201 tattcttctc ataaaggaga cgttggtaag aaagcagaga atctcattca aggccaattt
    31261 gaaggctcta aaacaatgga aaagtgctac acagatgtga cagaatttgc cattccagca
    31321 agtactcaaa agctttactt attaccagtt ttagatggct ttaatagcga aattatcgcc
    31381 tataatcttt caacttcacc caacttagaa caagtacaaa caatgttgga acaggcattc
    31441 acagagaagc actacgagaa tacgattctc catagtgacc aaggctggca atatcaacac
    31501 gattcttatc atcggttcct agagagtaag ggaattcaag catctatgtc acgcaaggga
    31561 aacagcccag acaacggcat gatggaatct ttctttggca ttttgaaatc ggagatgttt
    31621 tatggttatg agaagaactt tagatcttta gaaaaccttg aacaagctat tgtggactac
    31681 attgattact acaacaacaa acgaattaag gtaaaactaa aaggacttag ccttgtgcag
    31741 tacagaacta aatccttcgg ataaattaat tgtctaactt ttggggtgca gtacattttt
    31801 ggtatatata aaatttgtag gagctatatc tacaatttta tattcccagt ttatggatgt
    31861 cacttactat attcacaatg ttatacagtg ttttttctct aatatttaag gagtgttctg
    31921 tttctcgaat aaattcttca aagtttaacc cgtcaacttg ttcctgaaca agaaaataat
    31981 catccacgat ataaaattca tcagttaaat tagtagtata acttttatcg gctaattttt
    32041 ttagcatgtg agcttcattt tttatatcat caagagctgt ccattctcct tcagcatcat
    32101 aattcacaaa aggtcttgac tgcttgatga ttactttttg cccgtccgat tttctaattg
    32161 cccgataaac atttccttta tttgatctct taataatttt ttccattttg tatttattta
    32221 ttgcagagtc tttacttgaa atttcacatg tggtttgaaa ataattcctt ttttcttctt
    32281 ctgaaaataa atccattttc cagttaggga gactagggaa attttgtctc ttatcttcta
    32341 catagttctt ccttttttca tctagcaata aatagatgac ttttttattt ttttcatcat
    32401 aagcttgttt tttttaaaaa gccccatatc tataatgaac tagagaatgc attccacatt
    32461 gatagtcaga tagtattttt ggagccttaa attctgacag tctattcgta agattacaaa
    32521 tcatactctt agcttcagat tctgacttag gatatagagt tataaatttg ttagcagtag
    32581 ggctcatttc cctaggggaa ttaatttttt ttaattcctc taaattttta acgactttaa
    32641 agctacaatt atttagttgg gatagtttat acacaatctt aaaaatattt acagcgtctt
    32701 ttatttggga gcttatgtgt attttccacc cttgtgcagg caccttatct gataaataat
    32761 agtaattcca aatatcaccc tgttggaaat ttttatcaca ttttaaacat tctttctcta
    32821 ataaatccat aacaaactcc taattattaa aataggctag agacacagca ctagcctatt
    32881 ccgtaagtaa agctacttat tttatataaa atataactag cgacctgtaa ttaaacaagt
    32941 aaaagaacaa tacttaggga gacctgtgac aatgacatct tcctctggaa gtagttctaa
    33001 ttcaaacaat gtttgttcca tgactgtatc ctcctgttat gataaattcc agaaagcata
    33061 gagcaaattc gtggttcgtc tgactaaatt tcttatctga acaccacctt caaatacaaa
    33121 ttttagtcaa acttttattt tttctaactt tctaattata ttctaccatg tgtttttata
    33181 tgtcaagaat tttctgaata aactgtttat tttttatttt ttgacatttt tgcaaattgt
    33241 ttaaaatctt tcaattggat tcacttatta ctttaggaca ttgaaacttc tttcgccaga
    33301 ggtgcttata ttactgggaa gttgaagatt gaaatgtggt ataataagag gtaatagagt
    33361 tttggaaagt gagagaagat gatttcaaag agattagaat tggtagcttc ctttgtgtca
    33421 cagggggcta ttttactaga tgtgggaagt gaccatgctt atctgcctat cgagttggtt
    33481 gagagaggcc aaatcaaaag cgctattgca ggtgaggtgg tggaaggtcc ctatcagtct
    33541 gcggttaaaa atgttgaggc tcacggccta aaggagaaaa tccaagtccg tttagccaat
    33601 ggcttggcag cttttgaaga gactgaccaa gtgtctgtca ttaccattgc tggcatgggt
    33661 ggtcgtttga ttgctaggat tttagaagaa ggtttgggga agttagctaa tgtagagcgt
    33721 ttgatcctcc agcccaataa tcgtgaagac gacttgcgta tctggctaca ggatcatgga
    33781 ttccagattg tagcagaaag catcttagaa gaagctggaa agttttatga gattttggtg
    33841 gtggaagcag gacaaatgaa gctatcagcc agtgatgttc gctttggtcc cttcttgtcc
    33901 aaagaagtca gtccagtatt tgtccaaaaa tggcaaaaag aagctgagaa gctagagttc
    33961 gccctcggac aaatcccaga aaaaaatctg gaagaacgtc aagttctagt agataagatt
    34021 caagctatca aggaggtgct ccatgttagc aagtgaagtg atccaagctt atgaagcctt
    34081 ttgccctcag gaattttcta tggagggaga cagccgtggt ctgcaaattg gcactttaga
    34141 caagggtatc caaagggtca tggttgccct cgatattcgt gaagagacgg tggcagaggc
    34201 cattgaaaag ggtgtggact tgattatcgt caagcacgcg cctatctttc gtcctatcaa
    34261 ggacttgctt gccagccgtc cgcaaaatca gatttacatc gacctgatta agcatgatat
    34321 cgcagtttat gtcagccata ccaatattga tatcgttgaa aatgggctca atgactggtt
    34381 ttgtcagatg ctaggaatcg aggagacgac ttatctgcag gaaacaggtc cagaacgtgg
    34441 aattggacgt attgggaata ttcagcctca gacattttgg gaattggccc aacaggtcaa
    34501 gcaagtcttt gacctagata gccttcgaat ggtgcattat caagagaatg atttgcagaa
    34561 gcctatttca agagtagcaa tttgtggtgg aagcgggcag tctttctata aggatgcttt
    34621 ggcaaagggg gcagatgtct atatcactgg cgacatctac taccatactg ctcaggatat
    34681 gctgtctgat ggcttgttag cattggatcc aggtcactat atcgaagtgc tttttgtgga
    34741 aaaaatcgca gcactcctta ctcaatggaa agagaaaaaa ggctgggaac tagagatttt
    34801 acctagtcaa gcatcgacca atcctttccg tcatatctag ttagaaagtg aagacaatga
    34861 aaaaagttgc cattattgga gcaggaattg tgggagcaac agctgcctac tacctctcga
    34921 gagaaagtga cctagaggtg accgtttttg accatgagca aggtcaagcc accaaggccg
    34981 cagcaggaat tatcagtcct tggttttcca aacgccgtaa taaagcctgg tacaagatgg
    35041 cgcgcttggg ggctgatttt tatgtggatt tattagctga tttagagaaa tcaggacaaa
    35101 aaatcgactt ttaccagcgt tcgggagtct ttctcttgaa aaaggatgaa tccaagttgg
    35161 aagaacttta tcaactggcc ctccagcgca gagaagaatc tcccttgata gggcaattag
    35221 ccattctgga ccaagcttca gctaatgaat tattccctgg tttgcaggga tttgaccgcc
    35281 tgctctatgc ttctggtgga gcgagagtag atggccaact cttggtaact cgtctgctag
    35341 aagccagtca tgtcaagctg gtcaaagaaa aagtgactct gacactctta tcatcaggct
    35401 accagattgg cgaagaggtg tttgatcagg ttattttggc aacgggagct tggttggggg
    35461 acatgttaga gcctttaggt tatgaagtgg atgtccgtcc tcaaaaagga caactacgag
    35521 attatcagct tgcccaagac atggaagctt accctgttgt catgccagaa ggggagtggg
    35581 atttgattcc ctttgcaggt gggaaattat ccttgggcgc tacccatgaa aatgacatgg
    35641 gatttgattt gacggtagat gaacccttgc tccaacaaat ggaggaggcg gccttgcctc
    35701 attacccagt tttagctaga gcgacttcaa gggctgagcg tgtgggaatc cgtgcctata
    35761 ccagtgattt ctctcccttc tttgggcagg tgccagaatt ggcaggtgtc tatgcagcca
    35821 gtggactagg ttcatcaggc ctcacaactg gtcctatcat tggttaccat ctagcccaac
    35881 tgatccaaga caaggagttg accttggacc ctctaaatta cccaattgaa aactatgtca
    35941 aacgagtaaa aagcgaataa tactcaatga aaatcaaaga acaaactagg aaactagccg
    36001 cgggttactc aaagcactgc tttgaggttg tggatagaac tgacgaagtc agctcaaaac
    36061 actgttttga ggttgtagat agaactgacg aagtcagtaa ccatacccat ggcaaggcga
    36121 cgttgacgtg gtttgaattg gattttcgaa gagtataagc attttactga aattttatca
    36181 ggtagtttag gatggcaaat gacattccct gtcaaaaatg gtaaaataag aaaaaataat
    36241 ctgagaatcg aggaaaaaag atgcaagaaa agattttggt aactggtggt gccggtttta
    36301 ttggaaccca cactgttatt gaattgatcc aagcaggcca tcaagttgtt gtggtggata
    36361 atcttgtcaa tagcaatcgt aagagtttag aagttgttga aagaatcaca ggagttgaga
    36421 ttcctttcta tgaggcagat attcgtgaca cagataccct cagagatatt ttcaagcagg
    36481 aagaaccgac tggtgtcatt cactttgctg gtttgaaggc tgttggcgaa tcaacacgta
    36541 tccctcttgc ctactatgac aacaatatcg ctggaactgt cagccttttg aaagcaatgg
    36601 aagaaaacaa ctgtaaaaac atcatcttca gttcttctgc gacagtttac ggggatccgc
    36661 acacagtgcc catcttggaa gatttcccac tttcagtgac caacccatac ggtcgtacta
    36721 agctcatgct agaggaaatt ttgactgata tttacaaagc agactcagaa tggaatgttg
    36781 tcttgcttcg ttactttaac ccaatcggag cccatgagag tagtgatttg ggagaaaatc
    36841 caaacggtat tccaaacaat ctcttgccat atgtgactca agtagccgtt ggaaaattag
    36901 agcaagtgca agtgtttgga gacgattacg atacggaaga tggaacaggt gttcgtgact
    36961 atatccacgt tgtcgatttg gctaagggtc acgttgcagc tttgaaaaaa atccaaaaag
    37021 gttcaggact aaacgtttat aaccttggaa ctggtaaagg ttactcagtt cttgaaatta
    37081 tccaaaacat ggaaaaagcg gtgggacgtc ctattcctta ccgcatcgta gaacgtcgcc
    37141 caggtgatat cgctgcctgc tactcagacc cagcaaaagc taaagcagaa ctcggttggg
    37201 aagcagaact cgacatcacc caaatgtgtg aagacgcatg gcgttggcag agcaagcatc
    37261 caaatggatt tgaagactaa gatgatgatt tcaatcatcg tcccttgttt aaacgaagag
    37321 gaagtacttc ctctttttta tcaggctctg gaagctttac ttccagattt ggaaacagaa
    37381 atcgagtatg tctttgtcga tgatggatca agtgatggga ccttggaact cttaaaggcc
    37441 tatcgggagc aaaatccggc agtccattat atttctttct ctcgaaattt tggcaaagaa
    37501 gcagcccttt atgcaggctt gcaatatgcg acaggagatt tggtggtggt gatggatgca
    37561 gacctccaag atcctcctag tatgttgttt gagatgaaaa atgtactaga caaaaatgta
    37621 gacttggact gcgttgggac acggagaact agtcgggagg gagaaccctt ctttcgcagt
    37681 ttctgtgctg ttctctttta tcgcctcatg caaaaaatca gcccagtagc tctgccgtcg
    37741 ggtgtccgtg actttcgtat gatgagaagg tctgtggtcg atgccatttt aagcttgact
    37801 gagtccaatc gtttttctaa gggactcttt gcctgggtcg gctttaaaac ccactatctg
    37861 gactatccaa atgtcgaaag gcaggctggc aagaccagtt ggagttttag gcaactcttt
    37921 ttttactcca ttgaagggat tgttaatttt tcagatttcc ctttgactat agcctttgta
    37981 gctggtctcc tatcttgttt tctttctctg ctgatgacct tttttgttgt ggttcggacc
    38041 ctcattttgg gcaatccgac atctggttgg acctctctga tggctgttat tctctttctt
    38101 ggaggcattc aactcttgac cattgggatt ctcggtaagt atatcagtaa gatttattta
    38161 gagactaaaa aaagaccact ttatcttatc aaagaaaaaa gtgaccttcc tgattttaca
    38221 gaaaaaataa agtgaaaaga ctataatttt acatggaaat gtgctaaact agagggagtg
    38281 gattatcgcc attgatttag gcttcctggt ttccaatcag ggcgcgagtt gggcaatttt
    38341 taacagcctc taagacatcc tgactaggag aaatttcttt ttccagttgg tcagggtcat
    38401 cgtaaaaacg cacgattcca ttatcgtggt aatcaaataa atcagaataa gtttggcaaa
    38461 gtccacaggc gatacatcgt tcaggtataa gtgtgatttt catgttcata tttatattgt
    38521 aataagaaaa gtaaaaaaaa acaaggagta aggtatggca aaagaaccgt ggcaagaaga
    38581 tatttatgat caagaagaat caagagcagg gcgtcggcat cgaaaccacg gaggggctga
    38641 taggatggct aatcgtattt tgacgatcct agctagtatt ttctttgtaa ttgtggtggt
    38701 gatggtcatc gttctcatct atctatcatc gggggggagc aatcgcacag cagccttaaa
    38761 agactttcat gattctgatg caagtgtagt acaaatctca tcttcaagca gttctcagcc
    38821 tgagcagagt tcagagccag aatctacttc tagtagttca gaagaagctg ctaatcctga
    38881 aggaacgatt aaagttctcg caggagaagg ggaagcagct attgccgctc gtgcaggaat
    38941 ctccattgct cagttagagg ccttgaatcc tgggcacatg gctacaggat cttggtttgc
    39001 taatccaggt gatgttataa aaataaaata ggagccgata tgaaaacaat tcaaattgct
    39061 attgatggtc ctgcttccag cggtaagagt acggtcgcaa agattattgc taaggatttt
    39121 ggattcacct accttgatac aggagctatg tatcgtgcag cgacctatat ggctcttaag
    39181 aaccaattag gagttgaaga agtcgaagcc cttctagcct tgttggacca gcatccaatc
    39241 agctttggac gttcagaaac tggagaccag cttgtttttg taggagatgt ggatattacc
    39301 catcctatcc gtgaaaatga agtgaccaat catgtttctg ctattgcagc aattcctgaa
    39361 gtgcgtgaga aactggtttc tctccaacaa gaaattgccc agcaaggcgg gattgtcatg
    39421 gatggtcgcg atattggaac tgttgtattg ccacaagcag aattgaaaat tttcctagta
    39481 gcttctgttg atgagagagc agagcgtcgt tacaaggaaa atattgccaa gggaattgaa
    39541 acagaccttg aaaccctaaa aaaggaaatt gctgcgcgtg actacaagga tagtcatcgt
    39601 gagacttctc ctctcaaaca agcagaggat gctgtctacc ttgatacaac tggtttgaac
    39661 attcaagaag tagttgaaaa aatcaaagca gaagctgaaa aaagaatgta aatgtagaaa
    39721 agccgataga ttgatatcgg tttttttcta aatttgtcaa aatgctgatt ttagggtata
    39781 atagttgctg ttcgagaaat tttgattttc aaagaatagt gaatgatgat aaggagaaac
    39841 catgaacaat ttaccaaatt gtccaaaatg taactcagag tatgtctacg aagacggtgc
    39901 cctactggtt tgcccagagt gtgctcatga gtggaatcct gctgaagttg cagaagtaga
    39961 agaaggtctt gtcgctatcg atgccaacgg aaataaattg actgatggtg atacagtaac
    40021 tctcatcaag gacttgaaag taaaaggtgc gccaaaagat ttgaaacaag ggacgcgcgt
    40081 gaaaaatatc cgcatcgtag aaggcgatca caatatcgac tgtaagattg atggttttgg
    40141 tgccatgaaa cttaaatcag agtttgtgag gaagatttaa gcatgtcaaa acactataaa
    40201 cttgtatttt atagccgtat cttcttgttt ctagcggctt ttacgggagt ttatcttgaa
    40261 attactaggc atggtggttt tgggatgctt ctctattaca cggttctgtc caacctcttg
    40321 gtaactattt ttacccttta tcttctaaag gttatgagcc gtgtaggtga aaattggcaa
    40381 aggccaagtc tcttgcgctt aaaaggtggg gtcaccatga gtatcatgat tacctgtgtg
    40441 atttaccatt tcctcttggc gcccattgcg actaatttct ataccctaga aaatttcctt
    40501 tgccactata tcgttcccat ctggttttta gcggataccc tcttttttga caaacagggt
    40561 caatacaaga tttgggatcc agcagtgtgg accattttac cctttctgta tatgatgttt
    40621 gctcttttta atggcttggt tctaaaactc aatattccaa atgccaagga taatcctttc
    40681 ccttacttct ttttgaatgt gaacaagggt tggaatgttg tgtttaagtg gtgtctgatt
    40741 atctttgttg cctatatggt agcaggattt attttctact ttatcaagca aatcaagaga
    40801 aagtcatcct aatactcttc gaaaatctct tcaaaccacg ttagtttcca tctgcaacct
    40861 caaaacactg ttttgaacaa cctgcggcta gctttctagt ttgctctttg attttcattg
    40921 agtatgagat acaagggatt cattttcgaa tttaagaagg agtctacaaa ccaatgaggc
    40981 ttcttctttt cttgcttatt tgataactat caaaaaagta gaagattaag agaaatatag
    41041 aaagagattt catgaaacaa tttttagaac gggccagcat tttggctctc tccctcgttt
    41101 tgattacctc cttttccatt tcgagtgccc taccagccat gtttgactat tatcagggtt
    41161 attctaagga acaaattgag ctcttggtga gcttgccttc ctttggaatc atgatgatgt
    41221 tactgctaaa tggtttctta gaaaaaatat ttcctgagcg cttacagatt agtttgggct
    41281 tgctgatttt atcattgagc ggtacagctc ccttctggta ccaagcctat ccctttgtct
    41341 ttggaacacg gcttctcttt ggtttgggtc ttgggatgat caatgccaag gccatttcta
    41401 ttatcagtga acgctaccaa ggaaaaaggc gaattcagat gttagggcta cgcgcttctg
    41461 cagaggtcgt tggagcttct ctcattacct tggccgtcgg tcagttgttg gcctttggtt
    41521 ggacagctat ctttctagcc tatagtgctg gatttttggt gctgcccctt tatctgctct
    41581 ttgtccctta tggaaaatca aagaaagaag tcaagaaaag agcgaaggaa gcaagtcgtt
    41641 taactcgaga aatgaaaggc ttaattttta ccttagctat cgaagcggca gttgtagttt
    41701 gtaccaatac agctattacc atccgtattc caagtttgat ggtggaaaga ggattggggg
    41761 atgcccagtt atctagtttt gttcttagta tcatgcagtt gatcgggatt gtggctgggg
    41821 tgagtttttc tttcttgatt tctatcttta aagagaaact gctcctctgg tctggtatta
    41881 cctttggctt ggggcaaatc gtgattgcct tgtcttcatc cttgtgggtg gtagtagcag
    41941 gaagtgttct ggctggattt gcctatagtg tagtcttgac gacggtcttt caacttgtct
    42001 ctgaacgaat tccagctaaa ctcctcaatc aagcaacttc atttgctgta ttaggctgta
    42061 gtttcggagc ctttacgacc ccatttgttc taggtgcaat tggcttacta actcacaatg
    42121 ggatgttggt ctttagtatc ttaggaggtt ggttgattgt aatctctatc tttgtcatgt
    42181 acctacttca gaagagagct taggattgat tcctaagttt ttcttttgat actcaatgaa
    42241 aatcaaagag catagttgat tgagtttgga atagtacgct gtagctgcta aaatatttct
    42301 agaaattaat ttgacttttc taatagagtt attcatatct tatttcaatc tactatagaa
    42361 agctagccgc aggttgctca aaatagtgtt ttgaggttgc agatggaaac tgacgtggtt
    42421 tgaagagatt ttcgaagagt atgagatttt tatacccata caatatttgt tttaggtcct
    42481 tgtttacaga ctaatttctt gataaaatag aggttatgac gagatataaa gcaactattt
    42541 cctatgatgg ttatgccttt gctggctttc agcgccagtc tcatgcgcgt agcgttcagg
    42601 aagaaattga aaaaaccttg accagattaa ataaagggca aaccattact gttcacggtg
    42661 ctggtaggac agatagtggg gttcatgccc tgggacaggt cattcatttt gacctgcctt
    42721 atcagatgga tgaggagaaa ctccgttttg ccttggatac ccagtctcct gaagatattg
    42781 atgtgatttc gattgagctt gtggcagatg attttcattg ccgttatgcc aaacatagca
    42841 agacctatga gtttattgtg gatagaggac gtcccaaaaa tccgatgcgc cgtcactatg
    42901 ccacccactt tccctaccca ctcgatgtgg aacgaatgca gattgcaatc aaaaagctag
    42961 agggaaccca tgattttacc ggttttacag cctctgggac tagtgtagag gataaggttc
    43021 gcaccatcac agaagctagt ttaatagtcg atgagacagg acaatttttg acctttacct
    43081 tttcaggaaa tggtttcttg tataaacaga ttcgcaatat ggtggggact cttctcaaaa
    43141 tcggtaacaa ccgcatgcca gtagagcaga ttgatctcat cttggagaag aaggacaggc
    43201 aacttgcagg tcccactgca gcaccaaatg gtttgtattt aaaggagatt cgttatgaag
    43261 aataatcgta ttttagcact ttctggaaat gatattttta gtggtggtgg actgtcagct
    43321 gatttggcta cctatacctt gaacggcttg catgggtttg tagcagtgac ttgtttgaca
    43381 gccttgacag aaaaaggatt tgaagtcttt ccaactgatg ataccatttt tcaacatgaa
    43441 ttagatagct tgcgtgatgt ggaatttggg ggaattaaga ttggtcttct ccctactgtc
    43501 agtgtggctg agaaggcctt ggactttatc aaacaacgcc caggagtacc tgtggtgttg
    43561 gatcctgtct tggtctgcaa ggaaacgcat gatgtagatg tcagtgagct ctgccaagag
    43621 ttgattcgct ttttccctta tgtcagtgtg attacgccta atctcccaga agcagaatta
    43681 ttatccggtc aggaaattaa aaccttggaa gacatgaaaa ctgcagcgca gaaattgcat
    43741 gatttaggag cgccagcagt cattatcaag agaggcaatc gtcttagtca ggacaaggct
    43801 gtggatgtct tttatgatgg acagaccttt actatcctag aaaatccagt tatccaaggc
    43861 caaaatgctg gtgcaggttg tacctttgcc tctagcattg ccagtcactt gattaaaggt
    43921 gataaacttt tgccagcagt agaaagctct aaggctttcg tttatcgtgc tattgcacaa
    43981 gcagatcagt atggagtaag acaatatgaa gcaaacaaaa acaactaaaa tcgcccttgt
    44041 atccctatta accgcccttt ctgtagttct aggttatttc ttaaaaatcc caacacctac
    44101 aggaattcta actcttttag atgctggtgt cttctttgcg gccttttact ttggtagtcg
    44161 tgaaggagcg gtagtcggag gactagcaag tttcttgatt gacctcttat caggctaccc
    44221 tcagtggatg ttctttagct tggtcaacca tggcttgcag ggatttttcg caggatttaa
    44281 aagaaaaagt cagtggttag gccttatttt agcaactatt gccatggtag gaggctacgc
    44341 cttgggttct actttgatga atggctgggc agcagccctc ccagaaattc taccaaattt
    44401 catgcaaaat atggtaggga tgattgtagg atttattctt agtcaaagta tcaagaagat
    44461 taagtaatac tcttcgaaaa tctcttcaaa ccacgtcagc tttcatctgc aacctcaaac
    44521 cactgttttg agcagcctga ggctagcttt ctagtttgca ctttgatttt cattgagtat
    44581 aaagaggttg agtaaaaagt atttcaaata agaaaaacgc atagtatcag gtgttgaatg
    44641 aactgccccc caaaagttag acagaaaaaa tctaactttt ggggtgtttt attatgaaac
    44701 taacttatga tgataaagtt cagatctatg aacttagaaa acaaggatat agcttagaga
    44761 agctttcaaa taaatttggg ataaataatt ctaatattag gtacatgatt aaattgattg
    44821 atcgttacgg aatagagttc g
//
LOCUS       DAVLGK010000012        42817 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLGK010000012 DAVLGK010000000
VERSION     DAVLGK010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42817
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.012"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(346..738)
                     /gene="rpsI"
                     /locus_tag="VXE01_000751"
     CDS             complement(346..738)
                     /gene="rpsI"
                     /locus_tag="VXE01_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV0749710.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(757..1203)
                     /gene="rplM"
                     /locus_tag="VXE01_000752"
     CDS             complement(757..1203)
                     /gene="rplM"
                     /locus_tag="VXE01_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV0749711.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            1559..1876
                     /locus_tag="VXE01_000753"
     CDS             1559..1876
                     /locus_tag="VXE01_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV0749712.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(1921..2733)
                     /gene="folK"
                     /locus_tag="VXE01_000754"
     CDS             complement(1921..2733)
                     /gene="folK"
                     /locus_tag="VXE01_000754"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV0749713.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVEHTFETYPLVQEMKLELKKPWA
                     PVHLPLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIEKMRNRGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(2892..3446)
                     /gene="folE"
                     /locus_tag="VXE01_000755"
     CDS             complement(2892..3446)
                     /gene="folE"
                     /locus_tag="VXE01_000755"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV0749714.1"
                     /translation="MDKQKIEAAVKMIIEAVGEDSNREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(3439..4749)
                     /locus_tag="VXE01_000756"
     CDS             complement(3439..4749)
                     /locus_tag="VXE01_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0749715.1"
                     /translation="MKEFENNQWITNYRTDQPHFGLERMVELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKNMLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMADY
                     QSLLEGESAANLQGTTEFEIITAIAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAVAEQKAGIIKQGIPSVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGADYQVSHQESVVTGEVFDYTSVVRQGRFQTGLLGLHQIENAGMAIALLDTFCQE
                     DGRKLASNHLLAQALEETSWPGRLEIVSRDPLMILDGAHNPHAIRALLATLQERFADY
                     HKEILFTCIKTKALEDMLNLLEQIPDTEVTLTHFDDSRATDESVLKEAAQSRNLSYQG
                     WQDFLEQKLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENG"
     gene            complement(4751..5728)
                     /gene="folP"
                     /locus_tag="VXE01_000757"
     CDS             complement(4751..5728)
                     /gene="folP"
                     /locus_tag="VXE01_000757"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV0749716.1"
                     /translation="MMKSLEGVTDMSSKANHVKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYYVEIEEEIQRVVPVIKAIRKESNVLISID
                     TWKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKARAKVVIMFNPVMARPQHPSSL
                     IFPHFGFGQTFTEKELADFETLPIEDLMEAFFDRALSKADEAGIAPENILLDPGIGFG
                     LTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETEHGFRNRDTA
                     SAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(5824..6531)
                     /locus_tag="VXE01_000758"
     CDS             complement(5824..6531)
                     /locus_tag="VXE01_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0749717.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIIPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(6585..8003)
                     /locus_tag="VXE01_000759"
     CDS             complement(6585..8003)
                     /locus_tag="VXE01_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV0749718.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALIVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            8193..9005
                     /locus_tag="VXE01_000760"
     CDS             8193..9005
                     /locus_tag="VXE01_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0749719.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKNIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            9344..10363
                     /gene="adhP"
                     /locus_tag="VXE01_000761"
     CDS             9344..10363
                     /gene="adhP"
                     /locus_tag="VXE01_000761"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV0749720.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            10596..11585
                     /gene="manX"
                     /locus_tag="VXE01_000762"
     CDS             10596..11585
                     /gene="manX"
                     /locus_tag="VXE01_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV0749721.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            11613..12416
                     /locus_tag="VXE01_000763"
     CDS             11613..12416
                     /locus_tag="VXE01_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV0749722.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            12440..13351
                     /locus_tag="VXE01_000764"
     CDS             12440..13351
                     /locus_tag="VXE01_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0749723.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(13407..14741)
                     /gene="pepC"
                     /locus_tag="VXE01_000765"
     CDS             complement(13407..14741)
                     /gene="pepC"
                     /locus_tag="VXE01_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV0749724.1"
                     /translation="MNAIQESFTNKLFANYEANVKYKAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQTKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(14958..15680)
                     /locus_tag="VXE01_000766"
     CDS             complement(14958..15680)
                     /locus_tag="VXE01_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0749725.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(15903..16133)
                     /locus_tag="VXE01_000767"
     CDS             complement(15903..16133)
                     /locus_tag="VXE01_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0749726.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            complement(16143..17384)
                     /locus_tag="VXE01_000768"
     CDS             complement(16143..17384)
                     /locus_tag="VXE01_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV0749727.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKANMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(17406..17558)
                     /locus_tag="VXE01_000769"
     CDS             complement(17406..17558)
                     /locus_tag="VXE01_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749728.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            complement(17579..17857)
                     /locus_tag="VXE01_000770"
     CDS             complement(17579..17857)
                     /locus_tag="VXE01_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV0749729.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(17850..18113)
                     /locus_tag="VXE01_000771"
     CDS             complement(17850..18113)
                     /locus_tag="VXE01_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV0749730.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(18215..22606)
                     /locus_tag="VXE01_000772"
     CDS             complement(18215..22606)
                     /locus_tag="VXE01_000772"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV0749731.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFQTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPVEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(22710..24791)
                     /gene="fusA"
                     /locus_tag="VXE01_000773"
     CDS             complement(22710..24791)
                     /gene="fusA"
                     /locus_tag="VXE01_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV0749732.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(25216..25686)
                     /gene="rpsG"
                     /locus_tag="VXE01_000774"
     CDS             complement(25216..25686)
                     /gene="rpsG"
                     /locus_tag="VXE01_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV0749733.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(25706..26119)
                     /gene="rpsL"
                     /locus_tag="VXE01_000775"
     CDS             complement(25706..26119)
                     /gene="rpsL"
                     /locus_tag="VXE01_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV0749734.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            26536..30333
                     /gene="spuA"
                     /locus_tag="VXE01_000776"
     CDS             26536..30333
                     /gene="spuA"
                     /locus_tag="VXE01_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV0749735.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSILIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLIPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNDVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            complement(30433..31482)
                     /locus_tag="VXE01_000777"
     CDS             complement(30433..31482)
                     /locus_tag="VXE01_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV0749736.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            31539..31616
                     /locus_tag="VXE01_000778"
                     /pseudo
     CDS             31539..31616
                     /locus_tag="VXE01_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(31753..33561)
                     /gene="glmS"
                     /locus_tag="VXE01_000779"
     CDS             complement(31753..33561)
                     /gene="glmS"
                     /locus_tag="VXE01_000779"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV0749737.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSKTERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQVFDLVHELSIVAQSIESTLSEKET
                     IEVKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(33731..35110)
                     /gene="bglA"
                     /locus_tag="VXE01_000780"
     CDS             complement(33731..35110)
                     /gene="bglA"
                     /locus_tag="VXE01_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0749738.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(35210..37063)
                     /locus_tag="VXE01_000781"
     CDS             complement(35210..37063)
                     /locus_tag="VXE01_000781"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV0749739.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(37076..38335)
                     /gene="rseP"
                     /locus_tag="VXE01_000782"
     CDS             complement(37076..38335)
                     /gene="rseP"
                     /locus_tag="VXE01_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV0749740.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(38357..39160)
                     /locus_tag="VXE01_000783"
     CDS             complement(38357..39160)
                     /locus_tag="VXE01_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV0749741.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(39169..39927)
                     /locus_tag="VXE01_000784"
     CDS             complement(39169..39927)
                     /locus_tag="VXE01_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV0749742.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDCLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(40158..40730)
                     /locus_tag="VXE01_000785"
     CDS             complement(40158..40730)
                     /locus_tag="VXE01_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV0749743.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIGVIFFDPDISYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(40711..41682)
                     /gene="ruvB"
                     /locus_tag="VXE01_000786"
     CDS             complement(40711..41682)
                     /gene="ruvB"
                     /locus_tag="VXE01_000786"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV0749744.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            41842..41934
                     /locus_tag="VXE01_000787"
     CDS             41842..41934
                     /locus_tag="VXE01_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0749745.1"
                     /translation="MMELVLKTIIEPIVVGVVLRLVDKWLNKDK"
     gene            42275..42367
                     /locus_tag="VXE01_000788"
     CDS             42275..42367
                     /locus_tag="VXE01_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0749746.1"
                     /translation="MMELILKTIIGPIVVGVILRLVDKWLNKDR"
BASE COUNT        12463 a         9891 c         8263 g        12200 t
ORIGIN      
        1 agtagattga aactagaata gtacacctct acttctaaaa cattgttaga attcgatttg
       61 actatcctcg gtttgtccta ttcttatttc accttactat aaaaataagg taaacttttc
      121 aaaaaaacac gaaaaaagca cccatagggc aaacctttga gtgctttgaa acattgatat
      181 aattgtattg attagcgttt tgaggcaact gaccttgtca ggttgcagcc acatttgtaa
      241 gcgactaaag tcgcaacaac tgtgtcaatt gcaccaattt agtaagaaag tataaaaaag
      301 aacaccccga aaggtgctct gtataagtat agtaattctt tcgaattaac gtttactaaa
      361 ttgtgatgct ttacgagctt tcttaagacc tggtttctta cgttcaactt tacgtgagtc
      421 acgtgtaaga agtcctgcgc gtttcaatga atcgcggaag tctgggtcta cttgaagaag
      481 ggcacgagcg ataccgtgac ggatagctcc tgattgacca gcgtatccac cacctacaac
      541 gttaacgaaa acgtcgtatg aacctacagt tgaagtaact gcaaatggtt ggttgatgac
      601 aagacgaagg tcagcgtgtg ggatgtactc ttcaacatct tttttgttaa cagtgatttt
      661 accagttcct ggaacaaggc gaacgcgtgc aacagcgttt ttacgacgtc cagtacctgc
      721 atattgtgct tgtgacatac tttattgttc ctttccttag ataagtcctg aaatgtcaag
      781 aacttctggt tgttgtgcag cgtgagtgtg ctcggctcca acaaatactt tcaacttcat
      841 accttgagcg cgtccaagag tattgtgtgg aagcatacct ttaactgatt tctcgatcaa
      901 acgtactgca tttttagaac gaagttcacc tgcagagatt tgtttcaatc cacctgggtg
      961 gtttgagtga gtgtagtaga ttttatcagt tgctttttta ccagtcaatt taactttttc
     1021 agcattgata acaatcacga agtcacctgt atcagtgtgt ggtgtaaatg ttggtttgtt
     1081 ttttccgcga agtacgctag caactactgc agaaagacgt ccaagtggta catcagttgc
     1141 gtcaactacg taccatttac gttcaacttg gcctggttta gccataaatg ttgttttgtt
     1201 catgatttct cctatatata gttcgatttt tgtttacggt gatgggtgtt ccttcccatc
     1261 gaaaagtatt tggaaggttc cggggccttt caaatggggt aaacaatacc gcctactatc
     1321 ataccaaatt tcacccctaa aagtcaatag atataaaaaa tatttttcgg taacttctca
     1381 aaataactga aagttatata atcaagttaa tttgggaatt tacctattaa cttcggtaga
     1441 tttttgggaa ttttttccct atttctccct gtaactaaaa tccttttcaa aaaatcacct
     1501 tttcttgatt tttaatccta tttgctgtat gataagggaa aagaaagggg acagagatat
     1561 ggcttttacc aatacccaca tgcggtctgc tagttttggc attgttacca gcttgcccga
     1621 tgacatcatt gactcttttt ggtatatcat cgatcatttc ttaaaaaatg tctttgaatt
     1681 ggaagaagaa ctcgagtttc aattgcttaa taaccaagga aagattacct tccacttttc
     1741 aagtcaacac ctccctacag ccattgattt tgactttaac catcctttcg accctcgtta
     1801 tcccccaaga gtactggttt tagacatgga cggtagagaa actatcctcc tcccagaaga
     1861 aaatgaccta ttttaaaaac tctagccttc agttgcaagt aactgaaaac tagagttttt
     1921 ctattttttc aaagcatcat acaagttgcg gatcggttgt tttaatatcg gatggataaa
     1981 atgaggcgca atttcctgta aggactcaag gacaaaaagg cgttccgcta tgtaaggatg
     2041 aggcaatatg aggtcgtctg tataaaggat ctggtcctcc acaaagagca agtccaaatc
     2101 aatcaaacga ggtccccaat gcacttctct cacccgtccc agctctgact caatggctaa
     2161 caaggtttct aacaagtctt gtgctggtag ccaggtttcc acctcaacca cttgattggc
     2221 aaagctatcc tgctccactc caccccaagg ctccgtcgct aagacactgg actctttgag
     2281 aatatggata cctcgatttc gcattttctc aatggcttgt ttcaagtttg cttgtttatc
     2341 tcccatattg cttcctaggg cgataaaggc tcgttgctta cggcgatgga tggttacgga
     2401 gcaagtatct aacggcaaat gcactggcgc ccaaggtttt ttcagttcca gcttcatttc
     2461 ttggacaaga ggataggtct caaaggtatg ttctaccagt ttgtaggcta ccgtttcaat
     2521 caaatcttca ctcgtttcct gaaaccaagt cgtccactgc tgacacaatt ctccgtaatg
     2581 gacagaggct gttaaatcca agtctgtagc tgccttggtc atatcatagg ataggatggc
     2641 tgaaacgaca aatttctgcc ccaattcttt ctcactagga aaaagaccat gataggcaaa
     2701 catttccaaa tccttaatct gcagttgatc cataatgatt cctttctcga aaaatccgcc
     2761 caaagcggat tctttttata ctcaatgaaa atcaaagtgc aaactaagaa gctagccgca
     2821 ggctactcaa aacactgttt tgaggttgca gatggaagct gacgtggttt gaatttgatt
     2881 ttcgaagagt attatagtcc cattaaacga taagcctgat ctcggaggtc cttatctgtt
     2941 tcaaatagac cacgagctac tgtcgtcaag gttgcagtgc ctggttttct gacaccacgc
     3001 atactcatac acatatgttc cgcctcaatg acaacaaagg ctcctttagc gcctagatag
     3061 tccatcaagg catcggccac ttcgatattc aaacgttctt gaatttgtgg ttttttcgaa
     3121 taaacttcaa ccgtacgggc tagcttagat aaacctgcta cacggccatc tggaatatag
     3181 gcaatatgcg ctctaccata aaatggcaag aagtggtgtt cacacatggt atggaaaaag
     3241 atatcctttt ctaccaccat attatcgtca ataatctcaa aagattttga caaatgttcc
     3301 tccgctgttt gaccaagacc tgaaaaaatc tcttggtaca tacgagccac acgagcaggt
     3361 gtttcctgca agccctcgcg gttagagtcc tctcccacag cctcgataat catttttaca
     3421 gctgcttcaa tcttttgttt atccattctc gttcttcctc tccatcagat aggctctcac
     3481 ttggctcaag aaatacaagg aacctgtgac aatcctaact gtttgtttct cttctttttt
     3541 atctgtcaat ttctgctcta gaaaatcctg ccaaccttgg tagctgagat ttctagactg
     3601 agctgcctct ttcagcacgc tttcatcagt cgcccgacta tcgtcaaaat gtgtcagggt
     3661 aacctcggta tctgggattt gctccaacaa attcaacata tcctccaagg ccttggtttt
     3721 gatgcaagta aagaggattt ccttatgata atccgcaaag cgttcttgca aggttgccaa
     3781 taaagccctg atagcatggg gattgtgggc cccatccaaa atcatcaagg gatctcttga
     3841 cacgatttcc aaacgccctg gccaacttgt ttcttccaag gcctgagcaa gcaagtgatt
     3901 gcttgctagt tttcgcccat cttcttgaca aaaagtatca agtaaagcta tggccatccc
     3961 agcattctct atctggtgca aaccaagcag gccagtctgg aagcgacctt gtctgacaac
     4021 acttgtatag tcaaagactt cacctgttac cacactctct tggtgactaa cttgataatc
     4081 tgccccgtag gcaagtctcg gcgcatcttt cccttccgca atgcggtcaa taacagccaa
     4141 ggcttctgga gcaatgcgac ctgtcaccga gggaatgcct tgcttaataa taccagcctt
     4201 ctgctctgct acggcttcca aggtgtcacc aagtagggct acatgatcca gtccaatggt
     4261 cgtgatgcct gttagaatgg gctggcagac attggtacta tccaagagcc cacccatgcc
     4321 aacttccata atagccacat ctacttgctc tgaggcaaag taatcatagg ctatagctgt
     4381 aattatctca aactcagttg tcccctgcaa attagcagcc gattccccct caagcagcga
     4441 ctgatagtct gccatgagag cttctagtct agcttctggg atagattccc cattgatgct
     4501 aatctggtct gtgtaatgaa tgagataggg cgagctaaac acgccaactc tcagccctag
     4561 tttttctagc atatttttca aaaaagcaat ggtcgaaccc ttgccattag ttcctccaat
     4621 atggatgacc ttgagtttga gatggggatt gccacgcaaa gctaacagtt ccaccattcg
     4681 ttccaagcca aaatgcggtt ggtccgtccg gtaattggta atccactgat tgttttcaaa
     4741 ttctttcatc ttatttgtat tgttttaaat ctaaattttc cgcttcatca gccagacgaa
     4801 tagcggaggc aatttcaact gccatcctgt gactagctac gtcatgcacg cgcaccactt
     4861 ctacaccctg tctcgcagcg atactagtta catgagccga agctgtgtcc cgattgcgga
     4921 aaccatgttc tgtctcagga ttgacttcaa acccactttc ttcaaggata ttgatgacaa
     4981 atcgcttgcg cgaaactccg agaaagattg gatagccttt ctgatggagt ttatccagat
     5041 cccgtaaaag aagcagattt tctttcttag tcagaccaaa gccaattcct ggatccagca
     5101 ggatattttc tggtgcaata ccagcttcgt ccgctttcga tagggctctg tcaaagaaag
     5161 cctccatcaa gtcttcgatt ggcaatgttt caaagtcagc taactctttt tctgtaaagg
     5221 tttgaccaaa gccaaaatga gggaagataa gcgaactagg atgctgaggt cgagccataa
     5281 ctggattaaa catgatgacc actttcgctc tcgctttagc taccacatga gccatttttt
     5341 catcacccat gagaccagtg atatcattaa ctagattagc accagcagcc aaagcagctt
     5401 ctgctacctg actcttccaa gtatcaatag agatgaggac attactttcc ttgcgaatcg
     5461 ctttgatcac tggaacaaca cgctggattt cctcttctat ctcaacataa tagctactgc
     5521 ccggccgagt cgattctccg ccgatatcta gcatactggc tccttctgct atcaatttac
     5581 gagcctgctg gagtgcctgc tcaagagcaa aaaattgacc accgtccgaa aaggagtctg
     5641 gggttacatt gataattccg caaatagctg tctttacatg attggcttta cttgacatat
     5701 cggtcactcc ctcaaggctt ttcatcatat tatttctcta ttttaccata aaaagaaaaa
     5761 gatggccacg attgcattca tctttttccc agtagaaaga ggtcggttcc tacataaaaa
     5821 cttttaaaca gaaattccta atgtccgact cataatcacc acaagagcca acaaacagaa
     5881 agcaatccca ttaacaatca tgtgaagcaa gatcgacatt tccaaacgtt gggtcttgta
     5941 ggctgtccaa gatagaactg tcgacatacc tccataaatc aataaagaag gtaaattact
     6001 tggttgatgc aataaagcaa acacaatcgt accgactaca aatcccaagt tctccttgcc
     6061 tcggaaaatc tttttaggaa taatcccacg acacaagatt tcctcacaaa tcggagcaag
     6121 caaggctagc aagaagaaac tggaaatcaa cgaactattt tgaaccatat cattaatctg
     6181 agactggtta gctgttgtcg tctcatttga cagttgcaat aaaatggaac caagtatatt
     6241 tgacccgaca ataactagat aactcaagcc caaacgtgcc aaatctttag ctctaaaaaa
     6301 agaaaaatta aaactagcta acttggtttt acgagctccc ataataaata gagccagaac
     6361 cacaattgaa aggccagcaa ctatcagccc tgactgtagc agggctactt cttttaaagt
     6421 caaaatagag gtaaccacta ggggaacctg atataaaagg acggcaagta aaaagaccaa
     6481 aatccagcct gcacgattca acaattcttt ccacatattt ttctctttca tcacctatct
     6541 ccttttgtat taaaaaaggg gggaaatccc cctgggtcat tctattataa ggccatgctg
     6601 atgtagttaa ggataaacaa ggcatccaaa atccaaatca tgacatgaac atctttaact
     6661 tgacctttaa caagcttagt caaagtgtaa gtcaagaaac caactgcaat cccttgagtg
     6721 atagagtagc tgaatcccat aaagatagat gtgaagaagg caggaactgc ttcagacata
     6781 tcatcccaat ggatattttt caagctacca agcatcataa tcccaacgat aatcaagatt
     6841 ggagctgtag ccgctgttgg tacgatcgct agaagtgggc taaagaagct tgaaatcgca
     6901 aaacagatag ctacaatcaa ggctgtcaaa ccagtacgtc cacctgcacc gataccagca
     6961 gcagactcaa cataagtcgt tacgtttgaa gtacctgcaa tggcaccgac tgtcgttcca
     7021 atcaaatcag agtaaagagc cttatccaat ttggctgatt ggtgattttc accatttgtc
     7081 gctacgatac caactttttc acctgtaccg atcaaggtac caattgtgtc aaaaatatct
     7141 gtcaatgaga aggcaagaat ggccatcaga gtttcaggca agcgagctgt atctgaaacc
     7201 aaagctccta aaccttctga accaagagct gcaccaaaga ttgtcttcaa atcttcaaaa
     7261 gctgcaccaa catggttatt agcaaaatcg atactagaca aatcaaccaa accaactgca
     7321 atagcaagaa cagttgttgt caagatagag agaataattc cccctttaat ccctttgatg
     7381 acaaagaaga tagtaatggc aagtcctgca agagccacta aaacagctgg attattaaag
     7441 ctgaccaatc ctggaactgc tgaagagttt gctgcaatcg ttgcttgagc tttgtcagcc
     7501 ccttctccta caacagtata gttgcctgga tcaatcgtga atttcaaaag tccagcattc
     7561 ttaatcccta cataggcaag gaagacaccg ataccagctg aaatagctga gcgaagagca
     7621 ttgggaatcg attcaatgat cattttacga acatttgtca aggtaataat caatgaaata
     7681 atcccacaga tgaagaccat agctagggct tcttgccaag aataaccaag cccgaataca
     7741 actgtaaagg taaagaaggc attgagtccc atacctggcg cttgggcata aggtaagtta
     7801 gcataaaaag ccatcatcaa ggtacccgct actgcaccaa taatcgtcgc taggaagacg
     7861 ccctgagcag gcattcctgt ttgtgaaagt atttgtgggt ttacaaagag aatatagctc
     7921 attgcaaaga aagttgttaa accagcgaga acctctgtac gaacgtctgt accgttctct
     7981 tttagtttaa ataatttgtc catcatcaat ctccttttaa tttttacgaa caataataga
     8041 attatatcat ttatcattca ctttttcaat gtctttgttt gatttgttta agaaattaat
     8101 ccaatttcat tttttgtttg gaatctgctt ttctgcctgc tttctgttat aatagaagac
     8161 atcttatctg aaaacacact agaaaggtcc atatgacgaa aaaaattatt gcagttgacc
     8221 tggatggaac cctgctcaac tcagacagtc aaatttctga ctttaccaaa aaaaacatca
     8281 aaaaagttgc tgaaaaaggc catcaggtta ttattacgac aggtcgccct taccgtatgt
     8341 caaaagattt ttaccgtgaa ctgggcttag acactcctat gattaacttc aacggatccc
     8401 ttactcattt accagaccaa gtttgggatt ttgaaaagtg tttgactgta gacaaaaaat
     8461 atctgctaga tatggttcaa cgttcagagg acattcaagc cgattttatc gctggagaat
     8521 atcgtaaaaa attctacatt acaaatccca atgaagaaat tgccaatccc aaactatttg
     8581 gtgtagaagc tttccagcct gaagatcaat tccagcctga attggtgacc aaggacccta
     8641 actgtatcct cttgcagacc agagccagtg acaaatatgc cttggcaaaa gacatgaacg
     8701 ccttctacca gcatcaactt tctatcaata cctggggagg tccgctcaat atccttgaat
     8761 gtaccccaaa aggtgtcaac aaggcctttg ctttggacta cttgctcaag ataatgaatc
     8821 gtgacaaaaa agatttgatt gcctttggag atgaacacaa tgataccgaa atgctcgctt
     8881 ttgctgggaa gggttatgcc atgaaaaatg ccaatccaga gctactccct tatgcagatg
     8941 agcaaatttc ccttaccaac gaccaagatg gggttgccaa aaccctacaa gacttattct
     9001 tataacctat actgatactc aatgagaatc aaagagcaaa ctaggaagct aaccgtaggt
     9061 tgctcaaagc actgctttga ggttgtagat gaagctgacg tggtttgaag agattttcga
     9121 agagtatgac cagcttgcaa gctggtcttt gtgctctttt cacagtctca tcaaccagtt
     9181 aatcgattgt tctacttttt gtctccaaaa ccttggaaaa ggctttcttt tgtgatatac
     9241 ttcacatata aatacaagag agctcgtcac actcgactct gttgacaaaa aatcaatcca
     9301 gtcccgttgt ccctgttctc ggtcaatatc aaggaggata gctatgaaag ctgttgttgt
     9361 aaatccagaa agcactggtg ttgctattga agaaaaagta ctccgtccac ttgaaactgg
     9421 ggaagcactt gtagaagttg aatactgtgg cgtttgccac accgacctcc acgttgctca
     9481 tggtgacttt ggtcaagtcc caggacgtgt tcttgggcac gaaggtatcg gtatcgttaa
     9541 agagattgct ccagatgtga aaagccttaa agtcggtgac cgcgtcagcg ttgcttggtt
     9601 ctttgaagga tgtggcactt gcgaatactg tacaactggt cgcgaaaccc tttgccgtac
     9661 agtgaaaaat gctggctact cagtagacgg tggtatggct gaacaatgta tcgtaactgc
     9721 tgactatgct gtcaaagttc ctgacggact tgatccagcc caagcttctt ctatcacatg
     9781 tgctggagta acaacctata aagctatcaa agaagcaaaa gttgaaccag gccaatgggt
     9841 tgttctttac ggtgctggtg gacttggtaa cctcgctgtt caatacgcta aaaaagtatt
     9901 caatgctcat gttatcgcag tcgatatcaa caatgacaaa cttgcccttg caaaagaagt
     9961 aggcgctgac attgtgatta acggcctcga agttgaagat gtagctggac tcattaaaga
    10021 aaaaactgat ggaggagctc attcagctgt cgtaactgct gtgtctaaag ttgccttcaa
    10081 ccaggctgtt gactccattc gtgctggtgg tcgcgtcgtc gctgttggtc ttccttctga
    10141 aatgatggaa ctcagcatcg ttaaaacagt cctcgatgga atccaagtca tcggttctct
    10201 tgtcggaact cgtaaagact tagaagaagc cttccaattt ggtgcagaag gtctagtagt
    10261 cccagttgtt caaaaacgtc cagtagaaga tgctgttgcc attttcgacg aaatggaaaa
    10321 aggccaaatc caaggacgta tggtactcga cttcacccac taatctaatg gaaacctatt
    10381 ttaaaagttg gaagcttctt ccaacttttt tatattaaat tttaaataag aattcaagat
    10441 tactcctcaa aaactcaaca tatcaacata caaaaataaa aattttttaa ttttttatga
    10501 taaatagttg ctttttttat gaaaacggtt tatacttaaa cagtcttaaa gttttcttaa
    10561 atgaaaacta aaacaaaaaa ggaggaatga caataatgag tatcggaatc attattgcga
    10621 gccacggcga atttgctgcg ggtattcatc agtcaggatc tatgatcttt ggtgaacaag
    10681 aaaaggttca agttgtgacc tttatgccaa atgaaggtcc tgatgatcta tacgctaagt
    10741 ttaataacgc tgttgctgca tttgacgcag aagatgaggt tctagttttg gctgaccttt
    10801 ggagtggttc tccatttaac caagctagtc gcgtgatggg agaaaatcct gagcgtaagt
    10861 ttgccatcat cacaggactt aacttaccga tgttgattca agcctacaca gagcgcctca
    10921 tggacgctgc tgcaggtgta gaaaaagtcg ctgctaatat cattaaagaa gccaaagatg
    10981 gcatcaaagc tcttccagaa gagctaaatc cagtcgaaga agttgcaagc gctgcagctg
    11041 ctccagttgc ccaaactgct atcccagaag gaactgttat cggagacggt aaattgaaaa
    11101 tcaatcttgc ccgtcttgac acacgtctac ttcacggtca ggttgcaact gcttggactc
    11161 cagattcaaa agcaaatcgt atcatcgttg cttcagataa cgtggctaaa gacgaccttc
    11221 gtaaagaatt gattaaacaa gcagctccag gtaatgtcaa ggctaacgtg gttccaattc
    11281 aaaaactgat tgagatttca aaagacccac gttttggaga aacacatgcc cttatcttgt
    11341 ttgaaacacc tcaagatgcc cttcgtgcca tcgaaggcgg cgtgccaatc aagactctta
    11401 atgttggttc tatggctcac tcaacaggta aaacattggt caataccgtt ttgtctatgg
    11461 acaaagaaga cgttgctaca tttgaaaaaa tgcgtgactt gggtgttgaa tttgatgtcc
    11521 gtaaagtacc aaatgattct aaaaaagatt tgtttgactt gattaacaaa gccaatgtca
    11581 aataagccat tatttatgaa aggattttaa acatgtctat tatttctatg gttttagtag
    11641 tcgttgtagc cttctttgca ggtcttgaag gcatcctcga ccagttccaa tttcaccaac
    11701 cacttgtagc ctgtaccctt attgggcttg taacaggtca cttggaagca gggattatcc
    11761 tcggtggatc gcttcaaatg attgcccttg gttggtcaaa tatcggtgct gctatcgctc
    11821 ctgatgctgc acttgcttct gtcgctgctg ccattatcat ggttcttggt ggtgacttta
    11881 ccaagactgg tatcggtgtt gcccaagcgg ttgctatccc tcttgccgta gctggacttt
    11941 tcttgacaat gattgttcgt acaatttcag ttggtttggt tcatactgca gatgctgccg
    12001 ctaaaaaagg tgacttcggc gctgtggagc gtgctcattt cattgcgcta cttttccaag
    12061 gacttcgtat cgcgcttcct gcagctcttc tccttatggt accaactgaa actgtacaaa
    12121 gtatccttag tgccatgcca gactggctca aagatggtat ggctatcggt ggtggtatgg
    12181 tcgttgccgt tggttacgcc atggttatca acatgatggc aactcgtgaa gtatggccat
    12241 tcttcgctct tggtttcgtt ctcgctgctg tgtcagatat tactctaatc ggattcggtg
    12301 ctatcggtgt tgctatcgct cttatctacc ttcacctttc taaaactggt ggaaatggtg
    12361 gcggaggagc cgcaacttct aacgacccaa tcggcgatat cctagaagac tactaagata
    12421 agaaaggact gaaaacatca tgactgaaaa acttcaatta actaaatcag atcgtaaaaa
    12481 agtttggtgg cgttcaacct tcttacaagg gtcttggaac tttgaacgga tgcaaaactt
    12541 gggctgggct tatacactca ttccagctat caaaaaactc tatactaaaa aagaagatca
    12601 aatcgctgct cttgagcgtc accttgagtt cttcaacact catccatacg tagctgctcc
    12661 agtcatgggg gttactcttg cgcttgaaga agaacgtgct aacggtgtgg aaatcgatga
    12721 cgctgctatc caaggggtta aaatcggtat gatgggacct cttgctggta tcggtgaccc
    12781 agtattctgg tttacagtac gcccaatcct tggatctctc ggtgcttcac ttgcccttac
    12841 tggcaatatc ttggggccac tcctcttctt tgttgcatgg aacttgattc gtatgtcatt
    12901 cttgtggtat gttcaagaga ttggatacaa ggctggatca gaaatcacta aagatatgtc
    12961 tggtggtatc cttcaagata tcactaaagg agcttctatc cttgggatgt tcattcttgc
    13021 tgtccttgtt caacgttggg taaatattaa atttgctttc gatgtttcta aagttcaact
    13081 agatgaaaag gcttatatcc attgggataa attgccagaa gggtctaaag gtatccaaga
    13141 agcattcgca caagtaggac aaggattgtc tcaaactcct gaaaaagtta ctactttcca
    13201 acaaaacttg gatatgttga ttcctggatt atcaggacta ctccttactt tactttgcat
    13261 gtacttactt aagaaaaaag tatctccaat cactattatc cttgccctct tcgcagtggg
    13321 tattgtggca catgttcttc acatcatgta atcaagcaac taaaaaggaa ccaggttcta
    13381 aaatctgatt ccttttttct atgcttttat tcagccaagg ctcccattgg atcccatggt
    13441 gcaagtacga ttggttctgc tccataggca gcttgttctt ctgctgtcag caattcctta
    13501 cgaacaacga tttggtatgt gtattcgtcc atccaagcgt ctgaggcaac aaagtaacca
    13561 tctgtaccga ccttgtctcc ccatgagttt tcaaccttcc acttggttga tttaccattt
    13621 tcgtccaagt caacacctgt caagaccatg gcgtgggtca tcaagctttc gctatagtcc
    13681 aaacgtccag ccttgtcttg agtaagttta atgtccatgc ttgattcaaa gtcataaaca
    13741 tctgtcgcaa ggatgccagc cttacggttg ctgagctggc cgacatcaga accaaaccaa
    13801 acagtctcac ctgcttgcat ttgggcaatc gccaattctt tcaagcgctc cattggaacg
    13861 ttgatgtagc gaactgcacg gctaccaaca acattcccca acatctcaac tgtgtaagat
    13921 tttccgtaag gtttatcagc agttggagca ttgataacag aaacgtagtc ttctaaagga
    13981 agattgacat atttcttgta aaactcttgt ggtgtgattc ctttttcact tttgtagttg
    14041 ttatctttat cgcgataagc aaagtcaaac ttgcgtggtg gaagtcctaa tgacatagca
    14101 agaaagttaa agatttcttg caagaggtct tctttcttag tttgaacagt cgcttgatct
    14161 gcaccagaaa caagcaaatc acgcaagatt tgagcatctt gacgaagcaa tttattaagg
    14221 atcgcattta gctcacgact gctgctagat gaaacagact caggataaac tgacttaggc
    14281 acgacaccgt atttttcaaa gagggaaacg accatatccc attgaccgcc atcttgttga
    14341 ggtgtttgga gtaagaagct aaccttgcgg ctagtcaatt cttggtctga agtcgcaatg
    14401 acttgctcca agaaccagtt tgatttctca tacttatccc agaagaaagt gtgggcttgt
    14461 gacaactcaa agttctccaa tttgtattgc gagatgagtt tgtggcggaa ggtgttgaga
    14521 gccgcaaaca tccagcaacg accagacgct ttctggttag tgaccttgtc cttggttaaa
    14581 tccaatgaga aaacaggtgt gttgtctaca tggctttggc gacattccag agctgcaaaa
    14641 attccgttgt ggctggcagc attttcaatc gctttgtatt ttacatttgc ttcatagttg
    14701 gcaaatagtt tattagtaaa tgattcttga atcgcgttca tagattcctc cttttattct
    14761 acagtctatt ataactcttt tcacaaagga agcaactaaa aaacataaaa ggtaaggaca
    14821 ttctccctca cctttttcga atttatactc ttcgaaaatc tcttcaaacc acgtcaacgt
    14881 cgccttgccg tactcaagta cagcctgcgg ctagtttcct agtttgctct ttgattttca
    14941 ttgagtatta aactaaatta aataatatta gcgcggagaa tttctaattc ttccttggtc
    15001 aagcgacgcc attcccctcg ttccaggttc tcatctaata ctaaagttcc catagtcaat
    15061 cgttgcaagt ccaccacttc cttgccacag tagcccacca tacgcttgat ctgatgaaac
    15121 ttcccttctg caatggtcac acggatttgg ctttgattct tttctgtatc tatggataca
    15181 agctccagta tagcgggttg acaggtaaag tctttgagag gaataccctc agcaaatgtc
    15241 tccacatctt cttgggtcat gattcccttg acttgtgcca gataagtctt gtccacatga
    15301 cgcttgggcg aaagaagaac atgagccagc tgaccatcat tggtcaagag caaaagacca
    15361 tgcgtgtcaa tatccaagcg tcctactggg aaaacttcct tactccgcgc caagtcatcc
    15421 aacaagtcca gaacggttct gtgcttggga tcctcagtcg ctgagataac tcctttgggc
    15481 ttgttcatca tgtagtagac aaactcttca tactccaaca cttgcccatc aaagcgaatc
    15541 tcatctattt tttcatcaat ctgcaattta gctgattttt cttttttacc atttacagtc
    15601 acgcgcccag ccttgagcaa gtttttgacc tcagtccgac ttcccaccgc acaggcaact
    15661 aaaaatttat ctaatctcat agaactatta tatcatatca aaaggaggct ggtacaatga
    15721 ccaacctcct tttcgtttca tactcttcaa aaatctcttc aaaccgcgtc aacgtcgcct
    15781 tgccgtatat atgttactga cttcgtcagt tctatctgca acctcaaagc agtgctttga
    15841 gcaacctgcg gctagtttcc tagtttgctc tttgattttc attgagtatc agatttagga
    15901 aattaacttc ctcgtctcca aaaaatagct aaaacaatca tggctcctaa aatcgctggg
    15961 ataatagctg ttcctgataa aactggcccc caagttccaa agagcaagtg acctagaaag
    16021 gctccgatcc aaccgagaaa catttttcca aaacatccca ttcgctctcc acgattggtc
    16081 atagcacctg ctaaaaatcc cactaggaga ccaacgaaca tacttcctaa catattatct
    16141 ccttaatttg cccaattccc attacggaaa agaggtactc gcgttccatc ctcacgaata
    16201 ccatcgatat ccatttggtt agaaccaatc ataaagtcta cgtgaacatc tgaacggtta
    16261 agccctgcag cttcaagctc ctcttcgctc atctccgctc catcaacaac gctagtcgca
    16321 taggctgcac cgatagccaa gtggtttgac gcattttcat cgaaaagggt gttaaagaag
    16381 gtaatgcctg actgagaaat tggacttgga tctggtacca aggcacattc acccaaggca
    16441 cgcgcacccg cattttcaaa gacaaggtct ttcataacct gatcaccctt ctcagcagtg
    16501 atatctacga tttgtccatc cttaaaggtc accttaatgc cttcaatgat atttccgttg
    16561 tagctaagcg gttttgtaga agtgacataa ccatctgcac gacggaagtc aggcgctgtg
    16621 aagacctctt ctgtcggcat atttggcaag aattcttcgc cctgtgcatt gacagcacca
    16681 gctgattccc aaacgtggtt ctttggcaaa ccaagtgtta aatctgttcc tggcgctgtg
    16741 tagtgaaggg ctgaaaattg ctccttatta agcatattgg ccttgctctt gagaatggct
    16801 gcatgttcct cccaagcctt aacaggatct gcttcgtaga cacggcaagt tttgaaaatt
    16861 tggtcccaaa ggaaatcaac tgcttcttcg tcgctcgcag catttgggaa gactttctta
    16921 gcccactcaa gtcctgctgc agctgctaca gtccagctaa ccttgttaga ttgagttgcg
    16981 atacgcatag gcttcatggc aagtcccata gctttagcag aagctgaaag cttgtcagcg
    17041 tccactccgt tcaaggcacc cggatcagat gaacgaactc caagacggct agccttgttc
    17101 tccaagagat agttcatctc agcaatcttg tattctggca cattgtccaa acgctccatc
    17161 ggggcatgga ggaatttctc acggttaatc acatcatctg tccactgaac gatgacctca
    17221 tgcgcaccca aggcataagc ttctttcacg attagatgtg ccaattcacg ttgctccaca
    17281 tcaatagaga gagccaaagt gtgaccaggt tgcacgttaa ttccgttcgc aaccaacaat
    17341 ttcgcatatt tttctagatt ttctttaaaa tttggtaaaa ccattctgtt ttctcttttc
    17401 tatttttatt tttctctcaa agcagaaaag attcctgcta aagcaatagc acctgacaag
    17461 agtgctgtcg atagaagaat tgtacgatca gcaagttcta attgatattc aaataccttc
    17521 ttagccggct tatcttccgc aaatattctt agtttcatga gaaccccctt aaaatagatt
    17581 aaaataaatc actgtgactg cctgtcctca gcaaatttaa aatcaattcc gacttgtcta
    17641 ctttataaac caaaagccaa tctggctggg tatggcattc acgaactcct tgaaaatgct
    17701 tggatgccgt caatgaatga tcacgatatc tggcaggatg ttctttttct tgaaccagaa
    17761 aattcaaaac ttcttctaat aattctgcct tcaaaccacg cttcatagcc aacttaaaat
    17821 cttttttaaa ctgtttatga taacgaatct taagcacgta agtcctccat caaatctgag
    17881 actgattcaa aagactggct catattacga ttttggtcta aatccgttaa cgcttggagc
    17941 aacttccgat tttcgtctag tctaacatca aaaggtagtc cctgatattg aattgcctga
    18001 cgaaggaaaa tattaatagc tgttgtcata tccattccca gattactaaa cacctgttgg
    18061 gcctgctcct taacctcact atccagacgg atgcttatac tcatctttga catactctca
    18121 ccctctttcc atagactatt ttaacaaaaa agaaagctaa tgtaaatcta ttggatatac
    18181 gttagcctct tttaatagat tattaagcaa ttttttaaaa caactcatca aacaaactca
    18241 actggttatc ctctggcata tttccaagaa tacccatctc atccatcttt tcaaccaagg
    18301 ttgatgagag tccaccacgc ttgcgtagtt ctgttttaga gaggaattct ccctcttcac
    18361 gcgcccgcac cagttgcttg gcaacgttct ctcccagacc atccattgct acaaatggtg
    18421 ggataagggt atccccgtcg atgaggaact ctgtcgcctg actacagtag agatctaatt
    18481 taccaaactt gaaacctcgt tcccacatct cattgacaat ctcaagagtt gtatagagat
    18541 cgatttccac attagaggct tcattgttct tccgtttttc agagatttct tccattctgc
    18601 gcttgatggc ctccaagccc gcacccatgg tcttgatatc aaaagcctta gcacgaatgg
    18661 agaagtaagc acagtagtaa taaataggat ggtgaacctt gaagtaagct acacgcaagg
    18721 ccatcataac gtaggctgcc gcatgggcct tagggaacat gtacttaatt ttcccacagg
    18781 attcgatata ccactctggc accttattag ccttcatggc ttcgatatag ccatttctct
    18841 cctcttctga aatctttagc cacaaaccct tacgtacccg ttccataatg gtaaaggcca
    18901 tcttaggttc cagacccgca tgcatgaggt aaaccatgat gtcgtcccga caaccgataa
    18961 cagtcgatag gtccgctatt ccttgcttaa tcagatcctg agcattcccc aaccaaacgt
    19021 cagtaccgtg ggacagacca gacagctgaa gcaattccgc aaaggttgtc ggatgggttt
    19081 cgtctaccat tccacgtacg aaatttgttc caaactctgg aatccccaac atacccgtag
    19141 gcgttccaat ttgttcaggt gttaccccta gcacatcagt cccagaaaag agtgccatca
    19201 cgccttcgtc atccatagga attttattag ggtcaatacc agacaaatcc tgaagttttc
    19261 gaatcatggt cggatcatca tgtcccagta catcgagttt gaggacgttc tcatcgatat
    19321 cgtggaagtt aaagtgagtg gtctgccatt cagccgtgac atcatctgct ggatactgga
    19381 caggcgtaaa atcgtagaca tccatgtagt tcggaataac aacgattccc cccgggtgtt
    19441 ggcctgttgt ccgcttgaca cccgccgctc cttgagcgag gcgttctact tctgcatcac
    19501 gataaaactt gccataatct cgctcgtaac ccttgacaaa tccataggca gtcttggcag
    19561 ctaccgtacc aaccgttccc gcacggaagg catattcttc accaaagata tcacgcacat
    19621 ccaagtgggc gctaggctga tcttctcccg agaagttcaa gtcaatatca ggaaccttat
    19681 ccccatcaaa accaaggaag gtctcaaacg gaatatcctg tccgttttta ctgagtttgt
    19741 gaccacagtt tggacagtcc ttatggggca tatcaaatcc tgaaccgtac gaaccatctg
    19801 tgataaactc actgtactga cactgaccac agacatagtg aggagagaga ggattgacct
    19861 ccgtaatccc aatcatggtc gcaacgaaac tagatccgac agatccacga gaaccaacca
    19921 agtaaccccg ttcattagaa cgttgcacca gcatctgcga tgccagataa atcacagcaa
    19981 atccattccc cagtatggat gttaattctt tttcaatccg caaatcaaca atatctggca
    20041 gcggatttcc ataaatctca aaagctttct tataggtcaa ctcagcaact gtttcttcag
    20101 ccttgtcgat gaaaggcgta tacaagtcac ccttaacgac ttcaacgggt tcaaatattt
    20161 ctgccaaggc attggtgttt tcaataacca gtttacgagc cagttcctct cccaaaaagg
    20221 caaattcatc caacatctca ttagtcgttc gaaaatgagc ctttggaagt ggcgctggtt
    20281 gggcatgttc accatgaccg atagttcggt taatcatcgc accctgtccc aaactacgga
    20341 cgataatttc acgataaatc tcttcttccg gttcgatata gtgaacattt cccgtagcca
    20401 gaacaggctt gccaaggcga tctccaacct ctatcaaact cttgataatg gtctggagtt
    20461 cctccatatc cttgacctgc tctttggcaa tcaagggcgc atagatagcc ggtggcatga
    20521 cctcgataaa gtcataatac ttggccacct caaccgccgc atccacacct tgagaaacga
    20581 ccacgtcaaa aacttcaccc tctgaacagg ctgaacctaa aatcaagccc tctcgatggg
    20641 catctagaac cgttctcgga atccgtggca ctccttcaaa atacttggta ttagacaagg
    20701 aaaccagctt aaagatattt tttagaccta cctgattctt gacatagatg gtcgcatgct
    20761 tgatccgagc ttttttgtaa gaatctggac tgattagatc aatgttgagt ctagctaaat
    20821 cggtcacacc atgtttttct gctacctctt tgataaagat gaaaagcaga cgaccagtcg
    20881 cttccgcatc gtagttggcc atgtggtgat gttccaaggc cacaccaaaa cgcttggtca
    20941 aaggccccaa accatggcgt ttatactcag gatagaggtt tctagcaaac tccagcgtat
    21001 caataactgg ctgactaatc tttggaagac catgacgctc ataattagca ttcataaagc
    21061 caacgtcaaa ggcagcattg tgggcaacta ggaccgtatc cttgcaaaat tcttggaatt
    21121 cttgcaaaac ttgttctagt ggtttggcat ttttgacatg atcatctgta attccagtta
    21181 actctgtagt aaaagctgac aagggatgcc caggattgat aaattcatca aattcagcaa
    21241 taacattccc cttgtacatc ttagaggccg caacctgaat caagtcatta tagatagctg
    21301 aaagtcccgt cgtttccacg tcaaagacca cgtaggttgc ttctgataag tccatctcca
    21361 cttcgttata gacgataggg acacggtcct ccacgatatt ggcttccatc ccatagatca
    21421 gctggattcc cgctttctta gccgccttat agccatgtgg aaaggactgg acattcccat
    21481 ggtctgtgat agcaaccgcc ttgtgtcccc acttagcagc tgttgcaaca atctcttcga
    21541 cctctggcaa agcatccata gtcgacatgt tagtatgagc atgaaactca acccgacgct
    21601 caccttctgg catcaaatcc ttccgctcat agtgaacaac ttcctgcaga tcctgtacgt
    21661 tcatagtcaa atcgcgtgtg aagttattca tctccacatt ccctcgaact cggagccaag
    21721 aattcttctt gatgaggtca aacttctggg cctcttcctc gtttttaacc cacttttgca
    21781 tagaaaaact tgaagtatag tccgtcattt taaagttgat taaaacacga cctgttctag
    21841 tcactttttg ctccacatca aaaacaaccc cttcaaatac cagacgattt tcctctgtcg
    21901 tcacttcgat cataggagta atctccgcct tatccagctt gggtttagct gcagcttttt
    21961 tcgcttgaaa atcaaagact ggtttctctt ccactggagg aggtgccatc tgctccagtt
    22021 gttccatagc acggagcgct tcctcattgg cagcttgaac aatctgctca ttttcagcat
    22081 gaaaggcctc ttcctgctct tgggtcagga catcattctt ctcaacttga cagttaaaag
    22141 tttgaaaacc aaacttttca agttgcttgg ctaaattagg aagatgattc ttcttaaaat
    22201 gttccttatc aatcgcttca gatccttcaa taaatagctg attaccctca gcacgaactt
    22261 gcaaattttg ataaagggac ttaaaacctt gactagcaca tggaccttca gagaaagcct
    22321 ccctatagta ggactgcaag agctgatttg aaaattcttg agaccgagcc ttaatttcaa
    22381 aaacagcttt attgcctgtc ttagaaaatt cttcgctcaa acctttcttt aattctaaaa
    22441 agatttcaat cggtaaaata ttagaaaata cgaaatgaaa ctcccatacc ttactaattt
    22501 tatgaaccac aactcgctca atattggcct gtgctaaagc aggagcctgt ctcatttcag
    22561 caggcatccc caattgattc atcaaaattt caaaactatt tgacattcat tttcctcaca
    22621 ttattcttct actattttac catatttaga ggtattttct aaagacaaaa ggaagccact
    22681 aagtgacttc cttctagagt gaggacggat tagtcttcac ctttattttt cttaataatt
    22741 tcttcttgta ctgacttagg tacatcttcg tagtggtcaa ataccatcat gaatgtacca
    22801 cgtccttgag atgcagaacg aagaactgtt gcgtaaccga acatttcagc aagtggaacg
    22861 taagcacgaa cgatttggct gttaccgtgt gcttccatac catctacacg tccacgacga
    22921 gcagttacgt gacccataac atcaccaagg ttttcttctg gaacagtgat tgttacaagc
    22981 atcattggtt caaggatagc tggttgtgct gatttagcag cttctttaag ggaaagtgaa
    23041 gccgcaatct tgaaggcagt ttcagatgag tcgacatcgt gatatgaacc atcataaagc
    23101 ttagctttaa cgtcaaccat tgggtaacct gcaagaacac cgttagccat agattctacc
    23161 aaaccttttt caaccgctgg gataaattca cgaggaacca caccaccgac gattgcgttt
    23221 tcgaattcga atcctttacc ttcttcgttt ggagtaaatt caatccacac atcaccgaat
    23281 tgacctttac caccagactg acgtttgaag aatccacgtg cttgagtaga agcgcggaat
    23341 gtttcacggt aagatacttg aggagcacct acgttcgctt caactttgaa ctcacgacgc
    23401 atacgatcaa caaggacgtc aaggtgaagt tcacccatac ctgagataac tgtttcacca
    23461 gtttcaacgt ttgtttcaac gcggaatgtt ggatcttctt cagccaattt ttgaagggcg
    23521 atacccatct tgtcttggtc agctttagat tttggctcaa ccatcaattg gataactggt
    23581 tctggaacgt tgattgactc aaggatgatt ttagattttt catctgtcaa tgagtcacca
    23641 gttgtagtat ctttcaaacc aacggcagca gcgatatcac ctgagtaaac agtgtcgatt
    23701 tcttgacggc tgttagcgtg catttgaagg atacgtccga tacgttcacg tttaccttta
    23761 gaagtattca atacgtatga acctgattga agaacacctg agtaaacacg gaagaatgtc
    23821 aaacgaccta cgaatgggtc agtcatgatc ttgaaggcaa gagctgcaaa tggctcttcg
    23881 tcagatgctg gacgagtttc ttcagcgtct gtatctgggt taataccttt gattgctggg
    23941 atgtcaagtg gacttggaag gtagtcgata accgcatcaa gcatcaattg aacacctttg
    24001 tttttgaagg ctgaaccaca caatactggg aagaattcaa cgttgatagt cgctttacgg
    24061 ataccagctt tcaattcttc gttagtgatt tcttcacctt cgaggtattt catcatcaat
    24121 tcttcgtcag tttcagcaac tgcttcaatc aatttttcac ggtattcttg agcttggtca
    24181 aggtattcag ctgggatgtc ttcttcaagg atatccgtac caaggtcgtt agtatagatt
    24241 tcagctttca tcttgatcaa gtcaatgata ccacggaagt catcttcaga accgattggc
    24301 aattggattg ggtgtgcatt tgcttgaaga cgatcgtgaa gtgtgcttac agagtaaagg
    24361 aagtcagcac cgattttgtc cattttgttg gcaaatacga tacgtggaac tccgtactca
    24421 gttgcttgac gccaaactgt ttcagtttga ggttcaacac ctgattgtga gtcaagaacg
    24481 gtaaccgcac catccaatac acgaagagaa cgttgtactt cgattgtgaa gtccacgtgt
    24541 cctggtgtgt cgatgatgtt tacgcggtgg ttgttccatt gagctgttgt cgcagcagat
    24601 gtgatcgtga taccacgttc ttgctcttgc tccatccagt ccatttgtga cgcaccttcg
    24661 tgagtttcac cgattttgtg gattttacca gtgtagtaaa gaatacgctc agtagttgtt
    24721 gttttaccgg catcgacgtg agccatgata ccgatattac gagttttttc aagtgaaaat
    24781 tcgcgtgcca tgaggtttgt ttctcctatt tatttttgat ttctattcta ttataacacg
    24841 attttaataa aaacggatag gcaggaccta cccgttctca atgttttcat gctattgttg
    24901 gtttcaactt acgagatggt aagctgagtt atagctaata ctaatcgatt tagctaattt
    24961 gaacccgggc taaagttagt tagccgatgt gagctggaac gggatgctgc gtgaaaaaga
    25021 taaaactcct tgtattcgtt gaatactgcg tcagtttcct attttcacct tgcatcctta
    25081 ccgtgcctag catcatgatt tagttgagct caagctaaaa gtctggagaa aaagatgaat
    25141 ctcattggtt gcaaccgcaa cctgcttcga ttccctattt tctctgggac tttcttaacg
    25201 ctttcgcatc ctatcttacc aacggaagtg tgcgaatgca cggttagctt cagccatacg
    25261 gtgagtatct tcacgtttct taacagctgc accagtgttg ttagcagcat ccaagatttc
    25321 ttttgcaaga cggtcttgca ttgtgtgttc accacgaaga cgagcgattg ttaccaacca
    25381 acgaagtcca agtgttgtac gacgttctgg acgaacttca actgggactt ggtagttaga
    25441 accaccaaca cgacgtgcac gtacttcaag tacaggcatg atgttttcca tagctgtttc
    25501 aaatacttca agtgcatcgt tgccagtagc ttctttgatt tgctcaaaag caccgtaaac
    25561 gattgaagca gcagtaccac gtttaccatc aagcataacg cggttgataa gacgagtaac
    25621 tagttgtgaa ttgtatagcg gatctggcaa tacgtcacgt tttggagctc tatttttacg
    25681 actcatttct ctttatcccc tttccttatg cttttggacg tttagtaccg tatttagaac
    25741 ggccttgttt acgatcgtta acacctgcag tatcaagtgc accacggacg atatggtaac
    25801 gtacccctgg aaggtctttt acacgtccac cgcgaagaag caccacgctg tgctcttgca
    25861 agttgtgtcc gatacctggg atgtaggcag taacttcgat aaggttgctc aaacgtacac
    25921 gagcgaattt acgaagggct gagttaggtt ttttaggtgt cattgttcca acacgagttg
    25981 caacaccacg tttttgtggt gaagaaacgt ttgtttgaac ttttttatga ctattgtaac
    26041 caacgttcaa agctggtgat ttagattttt ctacttttga tttacgcggt ttgcgaacca
    26101 attggttaat tgtaggcatc tacattctcc tgtgtttttt tatttttggt gatgatacac
    26161 ttggtgacag atatcatctg tgtgtacttt tgcaacattt gtcagcacgt ccctgtacac
    26221 tcttgagaga ccaaaagtaa aaagtaccgt ctattattgt aacaaaattt tcccttgctt
    26281 gtcaagatat ttttcttttt tattggtaat gttagagatc aatttctgaa taaaaatagc
    26341 tgggaacaca tcatcttcct aataatacgg cttggcttat gtgacatttt tatctccgtc
    26401 atttatactg atatataaaa tagtacagaa aacttctcaa aagtaagaat ttttttcaca
    26461 aatcaaagaa aacgcttgca tattgtttta ctacatgcta tactgatata gaaatttatt
    26521 gattggagaa tcattatgag aaaaacacca tctcacactg agaaaaaaat ggtctacagc
    26581 atccgttccc tcaaaaatgg aactggttct atccttatcg gcgcaagcct tgtcttgctt
    26641 gccatggcta caccaactat ctcatccgac gaaagtacac caaccactaa cgaacccaac
    26701 aacagaaata caaccaccct tgcccaacct cttactgata cagcagctgg ctctggtaag
    26761 aacgaaagtg atatttcttc acctagaaat gcaaacgctt ccctagagaa aacagaagaa
    26821 aaacctgcaa cagagccaac tacttctact agtccagtaa caactgaaac taaggcagaa
    26881 gagcccatcg aagataacta cttccgtatc catgtcaaaa aacttcctga agaaaacaag
    26941 gatgctcaag gactatggac ttgggacgat gttgaaaaac catctgaaaa ctggccaaac
    27001 ggagctttgt ccttcaagga tgccaagaaa gatgactacg gctattacct agatgtcaaa
    27061 ttaaagggag aacaagccaa gaaaattagc ttcctcatca acaatacagc tggaaaaaat
    27121 ctaaccggcg ataaatctgt agaaaaacta attccaaaaa tgaacgaggc ttggttagac
    27181 caagattaca aggttttctc ttacgagcca cagcctgcag gaactgttcg cgtcaactac
    27241 taccgcacag atggcaacta tgacaagaaa tctctctggt actggggaga tgtaaaaaat
    27301 ccaagtagcg ctcaatggcc tgacggaaca gactttacgg ctacaggcaa atatggccgc
    27361 tatatcgaca ttcctcttaa tgaagccgca agagaatttg gatttttatt actagatgag
    27421 agcaaacaag gagacgacgt gaaaatccgt aaagaaaatt ataagttcac agatttgaaa
    27481 aatcatagcc aaattttcct aaaagacgat gatgaatcga tttacacaaa tccatactat
    27541 gtccatgata tccgtatgac aggagcccaa cacgtaggca cttctagcat tgaaagtagc
    27601 ttttcaacac ttgtcggtgc taaaaaagaa gatatcctca aacactccaa catcactaat
    27661 cacctaggaa acaaggtaac tattaccgat gttgcaatcg atgaagctgg taagaaagtg
    27721 acctacagcg gagatttctc tgacacaaaa catccttata ctgttagcta caattccgac
    27781 caattcacta ccaaaacaag ctggcacctg aaagatgaga catacagcta tgatggcaaa
    27841 ctgggagctg acctaaaaga agaaggaaaa caagttgatt tgaccctttg gtcaccaagt
    27901 gctgataagg tttctgttgt tgtctacgac aagaatgacc ctgacaaagt agttggaact
    27961 gtcgctctcg aaaaagggga aagaggaact tggaaacaaa ctctagacag cacaaacaaa
    28021 ctcggaatca cagatttcac tggctactat tatcaatacc aaatcgagcg tcaaggtaaa
    28081 actgttcttg cactcgatcc ttacgctaaa tctcttgctg cttggaatag cgacgatgcc
    28141 aaaattgacg atgcccataa agtggctaaa gccgcctttg tagatccagc taaactcgga
    28201 cctcaagact tgacttatgg taagattcat aatttcaaga ctcgtgaaga cgccgttatc
    28261 tacgaagctc atgtgcgtga cttcacttca gatcctgcca ttgcaaaaga cttgaccaaa
    28321 ccatttggga cttttgaagc cttcattgaa aaactagact atctcaaaga cttgggtgta
    28381 acccatatcc agctccttcc agtcttgtct tactactttg tcaatgaatt gaaaaaccat
    28441 gaacgcttgt ctgactacgc ttcaagcaac agcaactaca actggggata tgaccctcaa
    28501 aactacttct ccttgactgg tatgtactca agcgatccta agaatccaga aaaacgaatc
    28561 gcagaattta aaaacctcat caacgaaatc cacaaacgtg gtatgggagc tatcctagat
    28621 gtcgtttata accacacagc caaagtcgat atctttgaag acctagagcc aaactactac
    28681 cactttatgg atgccgatgg cacacctcga actagctttg gtggtggacg cttgggaaca
    28741 acccaccata tgaccaaacg gctcctagtt gactctatca aatacctagt tgatacctac
    28801 aaagtggatg gattccgttt cgatatgatg ggagaccatg acgccgcttc tatcgaagaa
    28861 gcttacaagg ctgcacgcgc cctcaatcca aacctcatca tgcttggtga aggttggaga
    28921 acctatgccg gtgatgaaaa catgcctact aaagctgctg accaagattg gatgaaacat
    28981 accgatactg tcgctgtctt ttcagatgac atccgtaaca acctcaaatc tggttatcca
    29041 aacgaaggtc aacctgcctt tatcacaggt ggcaagcgtg atgtcaacac catctttaaa
    29101 aatctcattg ctcaaccaac taactttgaa gctgacagcc ctggagatgt catccaatac
    29161 atagcagccc atgataactt gaccctcttt gacatcattg cccagtctat caaaaaagac
    29221 ccaagcaagg ctgagaacta tgctgaaatc caccgtcgtt tacgacttgg aaatctcatg
    29281 gtcttgacag ctcaaggaac tccatttatc cactccggtc aggaatatgg acgtactaaa
    29341 caattccgtg acccagccta caagactcca gtagcagagg ataaggttcc aaacaaatct
    29401 cacttgttgc gtgataagga cggcaaccca tttgactatc cttacttcat ccatgattct
    29461 tacgattcta gcgacgcagt caacaagttt gactggacta aggctacaga tggtaaagct
    29521 tatcctgaaa atgtcaagag ccgtgactat atgaaaggtt tgattgccct tcgtcaatct
    29581 acagatgcct tccgacttaa gagtcttcaa gatatcaaag accgtgtcca cctcatcact
    29641 gtcccaggcc aaaatgatgt ggaaaaagag gatgtagtga ttggctacca aatcactgct
    29701 ccaaacggcg atatctacgc agtctttgtc aatgcggatg aaaaagctcg cgaatttaat
    29761 ttgggaactg cctttgcaca tctaagaaat gcggaagttt tggcagatga aaaccaagca
    29821 ggatcagtcg gaattgccaa cccgaaagga cttgaatgga ctgaaaaagg cttgaaattg
    29881 aatgccctta cagctactgt tcttcgagtc tctcaaaatg gaactagcca tgagtcaact
    29941 gcagaagaga aaccagactc aaccccttcc aagcctgaac atcaaaatga agcttctcac
    30001 cctgcacatc aagacccagc tccagaagct agacctgatt ctactaaacc agatgccaaa
    30061 gtagctgatg cggaaaataa acctagccaa gctacagctg attcacaagc tgaacaacca
    30121 gcacaagaag cacaagcatc atctgtaaaa gaagcggttc gaaacgaatc ggtagaaaac
    30181 tctagcaagg aaaatatacc tgcaacccca gataaacaag ctgaacttcc aaatacagga
    30241 atcaaaaacg aaaacaaact cctatttgca ggaatcagcc tccttgcgct ccttggtctc
    30301 ggtttcttac taaaaaataa aaaagagaac taaactagcc ctcctataga aaaatccccc
    30361 aagcattata gctcggggga ttaatttttg tacaatattt gttgtcctaa taaacttgat
    30421 taggattttt tattaagcct ctttcatagc aaaataagct cgtactttgg gtgcaacttg
    30481 tgttccgaat agttcaatag ctctcagaac ctggtcatga ggcatagaac caagcggtag
    30541 atgaagcatg aagcggtcca atcctaaatc ctctatcatg cgaatcaatt tttcggccac
    30601 ctgatctgga ttgccaacaa acatggcgcc atttggccct acctgctcca aatattgctc
    30661 ataacgcaat tcctgccagt gcggacggtc tttggaaata gcatccacca cttgcttagt
    30721 cggatggaaa taatctttca ccgcctgctc accatcttcc gcaatccacc cccaagaatg
    30781 ggctcccact ttcaagtctt tgtcagcatg gcccgcttcg cttccaatct cacgataagc
    30841 ctgaatcaac tttttaaaat aacgtggatt accaccaata atagcatata caatcggtag
    30901 accagcctga gcaatcttca ctgttgattc gacatgacca cctgtagcta tccacaaggg
    30961 caatttgtcc tgaactggac gaggataaac ttctttacca gcaatcgttt gagtcaatcg
    31021 accttgccag tctaacttgg tcttttcatt gactaactga agcaagtcta atttctcatc
    31081 aaaaagagag tcgtagtctt tcaagtcata accaaacaga gggaaagatt ccgtgaaaga
    31141 gccccttcca gccataatct ccgatcgtcc atttgacaaa gcatcgatag tggcatactg
    31201 ttggaacaaa cgaatcgggt ccatgcttga cagaatgctg actgcactgg tcaaacggat
    31261 tttcttggta ttgactgccc cagcggccag gacaatctct ggggctgata ctgcaaaatc
    31321 cgcccgatgg tgctcgccaa ttccatatac gtccaaacca accttgtcag ccagctcaat
    31381 ctctgccacc aactggcgaa tgcgttcagc atgactgtaa gtttgtccag tcccttcaag
    31441 ctccgttatt tccccaaatg ttgaaattcc caattctacc attgtgattc tccttgtcta
    31501 tctctgtcct tcaatttgaa aaattattct aatactcaat gaaaatcaaa gagcaaacta
    31561 ggaagctagc tgcaggctgc tcaaaacagt gttttgaggt tgtggataga actgacgaag
    31621 tcagtaacca tacctacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt
    31681 ataacacgaa tcttgagtac aagcaaccaa tttgctcaca agaaaaagcc tagataacta
    31741 gactttttta gcttattcta ccgttactga cttggcaagg ttacgtggtt tgtccacatc
    31801 gaggccacga tggagggttg caaagtaagc gactaattgc gttggtacga ccattgaaat
    31861 tggtgagagg tatggatgta cggtcgtaag gacgatatcg tcggtatctt tggctacatt
    31921 ctcttctgcg atagtgagga ctttggcacc acgggctgcg acctcttgga tatttccacg
    31981 agtatggttg gcaagaactg gatctgacaa gagagccaaa acaggcgttc cttcttcaat
    32041 caaggcaatg gttccgtgct tgagttctcc tgcagcaaag ccttcacact ggatataaga
    32101 aatctctttg agtttgagac ttgcttccat ggctacgtag taatcttgac cacgtccgat
    32161 gtaaaaggcg ttacgagttg tttcaagaag ttcacgaacc ttgacttcaa tggtttcttt
    32221 ctctgaaaga gttgattcga tagactgagc tacgattgac aattcatgaa ccagatcaaa
    32281 gacttgcgct ttagcattac catttgcttc tccgactgct tttgcaagga aggcaagggc
    32341 tgcgatttgc gctgtatagg ctttagttga tgccacggca atttcaggac ctgcgtgaag
    32401 gagcatggta tagttggctt cacgtgagag ggttgaacct ggaacgtttg tcactgttaa
    32461 gcttggaatt cccatttcat tagccttgac caaaacttga cgactatccg ctgtttcacc
    32521 agattggctg ataaagatga agagtggttt cttgctgaga agtggcatac cgtagcccca
    32581 ctcagatgag attccaagtt caactggtgt atctgtcaat tcttccaaca ttttcttaga
    32641 agcaaatcct gcatggtaag atgttccagc tgcaaggatg tagatgcggt ctgcgtcttg
    32701 aacagcctta atgatatctg ggtctacgac aacttgacca gcctcatctg tgtaggcttg
    32761 gatgagtttc cgcataacag ttggttgctc gtcaatttcc ttgagcatgt agtaagggta
    32821 agttccctta ccgatatctg acaagtcaag ttcagcagtg tagctagcac gctcacgacg
    32881 atttccatca tagtcttgaa cttccacact atcagccttg acgattacca actcttggtc
    32941 atggatttcc atgtattggt tagtttcacg aatcatagcc atggcgtctg agcagaccat
    33001 gttatagcct tctccaagac caatcaaaag tggtgattta tttttagcta cgtagatgac
    33061 ttcaggatct tgtgagtcaa ccaaggcaaa ggcataagaa ccacggatga tgtgaagggc
    33121 ttttttgaag gcttcaagaa ctgagagccc ttcttcttcc gcaaattttc caatcaaatg
    33181 aacggctatt tcagtatctg tctgcccctt gaagtggtga cctgcaaggt attcttcctt
    33241 gatttcaaga tagttctcaa tcaccccatt atgcaccaag acaaaacgtt ctgtcttaga
    33301 gcggtgtggg tgagcattgt cctcagttgg ttttccgtga gtagcccaac gagtatgtcc
    33361 gataccagtt gttccctcaa caccagctgt cttggcagac aattctgcaa tacgaccaac
    33421 cgccttcacc aaatggttat cagcaccatc taggacaaaa attcccgcag aatcatagcc
    33481 acggtattca agcttttcaa gcccttgaat caaaatatca gttgcatttg tgtttccaac
    33541 aacaccaaca attccacaca tagtattttc ctttttaaaa ttggtatagt ctaattaacc
    33601 aaattggcaa tcagtgaagt tattataaaa cttgtttttt aaattgtcaa gaaaaaattg
    33661 gtatagttca aattaagctc ctgtaagcat aaaaactctg accgattggg ataatcagtc
    33721 agagtccttt ttaaaatcca ttattatcgc ttaattcttt gaaccagtgg cctgatttct
    33781 tcagacgacg ttcttgcgtt tccaagtcta attcgaccaa accataacga tttttatagc
    33841 tgttgagcca tgaccagcag tcaataaagg tccaaatcaa gtagccctta cagttggcac
    33901 catcttcaat ggcacggtga agttcacgaa gatgaccttt tacaaagtca atacggtaat
    33961 catcttgaat cattccatct tgacggaatt tttcttcccc ttcaacaccc ataccattct
    34021 cagtcaacat ccactcaata ttgccataat tttccttgat attttgggcg atgtcataaa
    34081 tcccttgctc ataaatctcc caaccacggt gagaattgat tttacgtcca ggcatcacat
    34141 aaggctcgta aaaatgttct ggtaagagtg gactctctgg atgcttagca aatcgaggag
    34201 ccataacacg caaaggttga tagtagttca caccaaggaa gtccaccgta ttatcacgaa
    34261 tgagttccaa ctcttcctct gtagcatcag gtaaaagacc gtgttcatgc aagatttcta
    34321 ccaactcctg tggataagtc cccaagacag atggatctaa gaaagattgg gcctgaaaaa
    34381 gggccgcaat acgagctgcc ttgacatcag caggatgctg gctacgtgga taagccggtg
    34441 tcaagttgag gacaatccca atcttggaat caggcaaaag ttcatggcaa gccttaacag
    34501 cccggctgct ggccaattgt gtatgatagg ctaccttaac agctgcctct gcatccacct
    34561 tatgtggata atgggcatca taaaaataac caaattctac aggaacgatg ggctcgttaa
    34621 aggtaatcca ttgatccact aaatctccat aagtctcaaa acaaaaacga gcatagtctt
    34681 cataggctga gactgtcgcc ttattttccc aaccatcacc atcctcttga agggcaaaag
    34741 gtaaatcaaa atgatagaga ttgactaaca gacgaattcc tttagcctta atagcctcaa
    34801 agaccttacg ataaaaatcc acaccttgag ggttgacttt tccacagcct tgtggaaaaa
    34861 tccgtgacca ctgaatagaa gtccgaaaga ctgtgtgacc agtctctaac aaaagctcaa
    34921 tatcccgctc ccaattttca taaaaagtcg atgtcttatc tgaaccaatc ccattatagt
    34981 aacgatttgg ctccacttgg aaccagtaat cccagagatt gtctccctta ccgtcaccag
    35041 ctacacgtcc ttctgtctgc ggtccagaag tagaggatcc ccagacaaaa tcctttggaa
    35101 atcttagcat aacatttacc tctttatcta ctcatttctc ccattataca gaaaaaacaa
    35161 ggtaaaaact agttacattt tttccttgtt tttcttctga ttatagtttt tatttcttgc
    35221 ttaggatttc aagcgtttca agcacgttat ctgcatgaac ctcaatggtg tcaccagttg
    35281 ccttgatctt aacttctaca atgccatcgg ccgctttttt accaacagtg atacggattg
    35341 gaagaccaat caagtcacta tcgctaaatt taacaccgac acgttcgtta cggtcatctg
    35401 tcaagacttc ataaccagct cccatcaagc ttgcttcaag tttttctgtc aaggcttgcg
    35461 cttcttcatc cttgacattg acagtaatca aatgcacatc aaatggtgcc aattctttag
    35521 ggaaattgat tccccaagcg taacggtatt caccttttgg cgttttgtta acaaagaggc
    35581 gagcgtgttg ctccatcact gctgaaagaa gacggctgac accgataccg taacatccca
    35641 tgatgattgg cacagcacga ccattttcat ccaagacatc tgctcccatg cttgctgagt
    35701 agcgagttcc gagtttgaaa atatgaccga tctcaatacc acgcgcaaag ttaaggacac
    35761 cttgtccatc tggggaaatt tcaccctcac gaacttcacg gatatccaca tattctgcag
    35821 taaaatcacg gcctgggttc acaccagtca agtggtagcc atcttcgtta gcaccgacaa
    35881 ctgcattgcg aacatcttgc accttacgat ctgcaataat tttaatattc tctggcaaac
    35941 caactggtcc aagtgaacca aatcctgctt gaacaacatt cgccacttct tcttcgctag
    36001 caacgtcaaa gaaatctgct cccaagtgat ttttcaactt gacttcgttg agttggtcat
    36061 ttccaactag aagggctgca acaagctcac catctgcaat gtagaagagg gttttaatcg
    36121 tttgttcttc tggaacattg aggaaggctg caacttcatc aattgattta acatctggcg
    36181 ttgcaacacg agtaacttct tcttcagcga caacacggtt gcttggtttg tactcgtttg
    36241 ttgccatttc taagttagct gcatagctag actcacttga gtaagcaatg gtatcttcac
    36301 cagagactat ccatttgagc aattctgcct tgatttcttc ttgcacttct gcaggaattt
    36361 cgtcaaatga ggcaactgac ttgtccaaga caacccagcg gtcaaggtct gtacgagcag
    36421 atgtaatggc cataaattct tggctatcct taccacccat ggctccaccg tcaccaataa
    36481 tagccttgaa gtctaaacca ctacgagtga aaatacgctc ataggctgct ttgtactcat
    36541 cataaacact atccaaacta tcatagttag cgtggaaact ataagcatct ttcatgataa
    36601 actcacgtgt acgaagaagt ccattacgcg ggcgtttttc atcacgatac ttgggctgaa
    36661 tttgataaag gttgagtggc aattgcttgt aagatttaac agaatcacgg acaatagctg
    36721 taaaggtttc ttcgtgagtt ggacctaaga taaagtctga tttttcacgg ttttttagtt
    36781 tgtaaaggtc ttcaccatag gtttcgtaac gacctgattc acgccacaat tctgcactaa
    36841 gaagggcagg agccaacatc tcaacagcac caatcttttc gaattcttgg cgcatgatgt
    36901 ttttagcttt ttcaatcaca cggttggcaa gtggtagata agaataaaca cctgctgaaa
    36961 cttggcgaac ataaccagca cgcaacataa gagcatggct gataacttga gcatcgcttg
    37021 gcatttcgcg aagcgttggg ataggcattt tactttgttt cataatattc ctcgattatc
    37081 taaaaaagag tcgcataatg tcattccaag tcacagcaat catcaagaca accatgatga
    37141 ccactccggc caaggtgaca taggtttcaa tttcttgttt caatggtttg cgacggatgg
    37201 cttctaggat attgagcaca atcttaccac catccaaggc tggaatcgga ataagattaa
    37261 aaatcccaat attgatggaa atcattgcca agaagtacaa gatattctca attccatttt
    37321 tagcagcatc actacttgcc ttaaagatag caacaggtcc acccaacttg ttcaaatccg
    37381 gttggaaaat cagatttttc agagctgaga gaattcggag agctgagtca gcagcagttg
    37441 taaaaccacc tacaaacatg gatagaaaat ctgacttaac ccccggttga acacctagaa
    37501 ggtaacgacc ttgactatct tcgggtgtaa cagtgacttg tttgtcactc cccttttcag
    37561 aaatagtcac atccaaagtc ggtgccgtct tatctttggt ttctgtttcc acagcttgga
    37621 tcaagctttc ccagttgcta acctcatgtg agccaatctt ggtaatttgt gccgtttctg
    37681 gtactcctac cttggccaag gcaccttggg gcatgatatg gaactgattg gtatcaacat
    37741 ctctgacacc accctgcata aagattaaaa cccaaaaaac aacgacacct aagataaaat
    37801 tgttcatagg acctgcaaaa ttggtaatca gtttgcccca gatagtcgca ttttgatatt
    37861 gaacatctaa aggcgcaatc cgaacctcag taccatctgc ttccacaacc gttgcatcgt
    37921 gatccactgc aaatgttttt tcttcttcca gaaccaatcc tttgataaag agcttgtctt
    37981 caaaatcaaa ctgggtcacc tgcataggga gggctgtttg atccaatttt ttacctgaga
    38041 gattgatgcg tttaacctta ccatcatcag caagtgtcaa actaacaggc gttcctgtct
    38101 tgatttcagt tgtatcatca ccccaaccgg ccatgcggac atagccaccc agaggcaaga
    38161 ttcgaatggt ataggccgtt ccatccttgc caatgtgagc aaaaatttta ggtcccatac
    38221 cgatggcaaa ttcacgtact aaaatccctg atttcttggc aaagtagaag tggccgaact
    38281 cgtgcaccac tacaataatc ccgaaaacca gaataaaggt taaaattccg agcatagcgt
    38341 ttcctccgtc ttttgattaa aagagtccaa ataagtgcat gattggaaat acaagcaaca
    38401 tactatcgaa acgatccaaa acaccaccat gtccagggat aaatttccca gaatccttaa
    38461 caccaaaatg acgtttgatc gaactttcta gtaaatcacc aaattgtcca gcaatgctaa
    38521 agaaaatagc aaagactgac atcttgtaaa ttccatatgg aagagcaact gtactgtcaa
    38581 ctatcataaa gataatggtt actaaaattg ctcctaaaat accacccaag gcaccctcaa
    38641 gggttttatt aggcgatacc cttggtgcta actttcgttt cccatagttc atcccaacaa
    38701 gataggcacc actgtctgtc gcccagacga tacacaaggc taagagagcc ttgtccaaac
    38761 ctgcaacacg agcatctagt aaagcattaa atccaaagcc cacgtagaag ctcatagcaa
    38821 gagggaaaac cgcatcctca atcgtataag acttgctaaa aacggtcgtt cctaacatga
    38881 ttgaaatcaa aacactatag gcaaccacat tcccatcaac tggcaaaaaa gtcaggtaat
    38941 tctccaaggg aatggtcaat gcaaaggttg caaagagggt caagaggccc tccatcgtca
    39001 tggtctctag acctctcatc ttcaaaagtt catgcatggc tagcatggct atgattccga
    39061 ttgctatctg aagcaagagg cccccaatca ttaaaattgg taggaaaata gccagggcaa
    39121 tccctgcaaa caaggttctt ttctgtaaat cctgggtcat atttcctcct aaactcctcc
    39181 aaatcggcga tgacgacgat tataggcaag aatagcttcc tgcaaggccg cttcgtcaaa
    39241 atcaggccat aaggtgtccg taaaataaag ctcactatag gctccctgcc atggaaggaa
    39301 attgctcaaa cgtaattctc cactagtacg gataatcaag tctgggtctc gtaagtcctt
    39361 aggtaaatgc tgagtaaaga gatagttacc aatcaattcc tctgtgatgt cacctgggtt
    39421 gattttggca tctaaaacat cctgggaaat caacttaagc gcctgtgtaa tctcagcacg
    39481 tccaccatag ttaagagcaa aattaagaat caatcctgtg ttgttcttag tcaattcctc
    39541 agccttggtt aaagcttcaa aggtttgctt aggcaggcag tctgtctccc caatcatttg
    39601 aatcttaaca ttattcgcat gtagttccgg gacataatta tcataaaact ctactggcaa
    39661 gttcatgata aacttgactt cctgatctgg acgggtccag ttttccgtag aaaaagcata
    39721 gaccgtaata accttgacgc ccagtttgtt ggctgccttg gtcacggttt gcaatgcttc
    39781 catgcccgct ttgtgtccaa aaactcgcgg ttgcatacgt tttttagccc aacggccatt
    39841 gccatccatg atgatgccga tatgagcagg aacctgtgtc ggaacctcta cttccacagc
    39901 cttatctttc ttaaaaaatc caaacatgat cttattccta ttcaaaaatc tatcgtttca
    39961 ttataccata tttccccatt ttcttctatc actaagctat ttattctcag gcaccatacc
    40021 catttttcaa aaaaataagc cgcctgattg ggcgacttta tttttatagg gagattatta
    40081 tgaaaaagtt ttaggagttt aagttaaggt cttcttaact tatgaactta gtgtacactc
    40141 cctagcttaa agtttcctta agtattttta aaaatcaaat ttttccattt ctcctgccaa
    40201 tttttcttgg ataaacgtgt ttgatagagt tccattcggt cttcattttc taagaaatga
    40261 ggagttggac gaacttgaaa attcaaaata tcctccaaac cataaggtac atagagttca
    40321 aaatctgatt cttcattcaa gcgcagtcca actgccgtac accgttctgg atacttactc
    40381 atagcatcac gagaactggt ataggaagca gtgtgaggac tgtgctgatg catatagacc
    40441 tgatttttca attcccactg gtactgagga aagtcctctc gcagtttttt ctccagtaat
    40501 aaggtttcct cataagaaat atccggatca aagaaaatca cacctatatc tgtttcatga
    40561 tcaaaagggg atttgtctga caaaagattc caaatgaaat ttctgacaga acctgctgcc
    40621 aaccacgagt ctttcagacc aaggtctcgg atgatcgtca gaatggccat catatctgga
    40681 ttttctctaa aagcctctaa gatttcttgc ttatttttca ctgtattcat aacctaagtg
    40741 ctcatatgcc ttagcagtcg ccacccgtcc agaccgtgtc cgcatgataa aacctttttg
    40801 aatcaagtaa ggctcataca tatcttcaac tgtctcacgc tcttcggcga tattcacaga
    40861 aagagttcct agaccaacag gtcctccact gtacatctca atcatggtac gaaggatttt
    40921 ttgatccaca tagtccaaac cttcatggtc aacatccagc atagtcaaag ccttatcggt
    40981 aataatatca tcaattaccc cattccccat tatctgggca aaatcgcgca cgcgcttgag
    41041 gagacgattg gcaatacgag gggtcccacg actacgtagg gccaactcag atgctgcctc
    41101 atgagtgatt tccatctcaa aaatatctgc cgtccgctcg acaatttctg tcaagtcagc
    41161 atgggcataa tactccatat gacctgtaat cccaaaacgt gcccgtagcg gattggagag
    41221 cataccagcc cgagtcgtcg caccaatcaa ggtaaaaggt ggtaactcca aatgaacact
    41281 acgactaccc tcaccagccc caatcataat atctatgtag aagtcctcca tagcactata
    41341 aagcacctct tccactgaca ttggcaaacg atggatctca tcaataaaaa ggacatcccc
    41401 aggctctaac tcattcaaaa tagctaccag atctccggct ttttcaatga ctggacccga
    41461 cgtttgcttg agattgactc ccagttcatt ggcaataaca aaggccatgg tcgttttccc
    41521 gagacctgga ggcccaaata agagcacatg atccagcgct tcatcccgca tttttgcagc
    41581 ttcaataaag atttgaagct ggtccttaac cttatcctgc ccaatatatt cacgtaagta
    41641 ctgaggacgg agcgtgcgtt ctactaactc ctcgtccccc attatctcat tatctaaaat
    41701 tctactcatg gctctattat atcaaaaaac caagccacaa acaaaaaagt cactggattg
    41761 gtgcttcccg agtttagcac ttatgtggta taatattata cggcacttct acaccgccta
    41821 cgaaaggagg tgagatagcc catgatggaa ttagtactca aaactatcat cgaaccaatt
    41881 gtggtcggtg tcgttcttcg attagtcgat aaatggctaa acaaggacaa atagtgtcaa
    41941 aaaagacctc aagcttattt ggtcgtgagc ttggggtctt ttctagccta tgatatagaa
    42001 ctagtactca attccttttt attatcccat agttcacaca ttttgtcaaa gttttatatt
    42061 ttcatccatt cagcttctcc aactttagaa tctgtccaat aaagtttata agattaagtg
    42121 aaagttatcg gaaaatgatg tttaaaatag tccccaaaag cctgaaatag agcaaaaaac
    42181 tccacctggt tgggtgactc ccgagtttag cacttatgtg gtataatatt ctacggcact
    42241 gctacaccgc ttgcgaaagg aggtgagata gcccatgatg gaactaatcc ttaaaactat
    42301 catcggaccg attgtggtcg gtgtcatcct tcgcttagtc gataaatggc taaacaaaga
    42361 tagatagtgt caaaaaagac cccaagctta atgtggaagt tagcttgggg tcttttctag
    42421 tccatgatat agaactaatc cttaattcct ctccattatc ccacagttca caaaatttgt
    42481 caaaacttta catcctcagc ttctcaagct ttaaccgctt tacaacaaga ctttcaattt
    42541 taagagaaag ttagggattc tatcaatttc atagaaattt tgatttagta aacgaagaga
    42601 caatcttata tgtcactcct catttaatac gccactactg gacaagcaaa atcattatta
    42661 cagcagttcc agtccttcaa ttaacagcaa cttacaatca agttgaggac gaacttgctg
    42721 aagcgacaac cgacctattt cttagtcata ttcgctaaaa aaatccccgc caaaatctca
    42781 aaaagtcccc gccaattccc cgaccaaaat ccgaaaa
//
LOCUS       DAVLGK010000013        40262 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLGK010000013 DAVLGK010000000
VERSION     DAVLGK010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.013"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            5..75
                     /locus_tag="VXE01_000789"
     tRNA            5..75
                     /locus_tag="VXE01_000789"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VXE01_000790"
     tRNA            110..183
                     /locus_tag="VXE01_000790"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            267..356
                     /locus_tag="VXE01_000791"
     tRNA            267..356
                     /locus_tag="VXE01_000791"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:303..305,aa:Ser,seq:tga)
     gene            367..440
                     /locus_tag="VXE01_000792"
     tRNA            367..440
                     /locus_tag="VXE01_000792"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:401..403,aa:Met,seq:cat)
     gene            444..516
                     /locus_tag="VXE01_000793"
     tRNA            444..516
                     /locus_tag="VXE01_000793"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:477..479,aa:Phe,seq:gaa)
     gene            529..609
                     /locus_tag="VXE01_000794"
     tRNA            529..609
                     /locus_tag="VXE01_000794"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:563..565,aa:Tyr,seq:gta)
     gene            614..684
                     /locus_tag="VXE01_000795"
     tRNA            614..684
                     /locus_tag="VXE01_000795"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:646..648,aa:Trp,seq:cca)
     gene            699..771
                     /locus_tag="VXE01_000796"
     tRNA            699..771
                     /locus_tag="VXE01_000796"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:732..734,aa:His,seq:gtg)
     gene            782..853
                     /locus_tag="VXE01_000797"
     tRNA            782..853
                     /locus_tag="VXE01_000797"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:814..816,aa:Gln,seq:ttg)
     gene            863..946
                     /locus_tag="VXE01_000798"
     tRNA            863..946
                     /locus_tag="VXE01_000798"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:897..899,aa:Leu,seq:caa)
     gene            1053..2330
                     /locus_tag="VXE01_000799"
     CDS             1053..2330
                     /locus_tag="VXE01_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV0749747.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFSLNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2406..3890
                     /locus_tag="VXE01_000800"
     CDS             2406..3890
                     /locus_tag="VXE01_000800"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV0749748.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3951..5231
                     /locus_tag="VXE01_000801"
     CDS             3951..5231
                     /locus_tag="VXE01_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0749749.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGITGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMILKG"
     gene            5235..5855
                     /locus_tag="VXE01_000802"
     CDS             5235..5855
                     /locus_tag="VXE01_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0749750.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6021..7163
                     /locus_tag="VXE01_000803"
     CDS             6021..7163
                     /locus_tag="VXE01_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0749751.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVFWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVEEATPQETTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7569..7907
                     /locus_tag="VXE01_000804"
     CDS             7569..7907
                     /locus_tag="VXE01_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0749752.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            7918..8276
                     /locus_tag="VXE01_000805"
                     /pseudo
     CDS             7918..8276
                     /locus_tag="VXE01_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            8383..9001
                     /locus_tag="VXE01_000806"
                     /pseudo
     CDS             8383..9001
                     /locus_tag="VXE01_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9029..9886)
                     /locus_tag="VXE01_000807"
     CDS             complement(9029..9886)
                     /locus_tag="VXE01_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV0749753.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10016..11158
                     /gene="tgt"
                     /locus_tag="VXE01_000808"
     CDS             10016..11158
                     /gene="tgt"
                     /locus_tag="VXE01_000808"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV0749754.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11259..13076
                     /locus_tag="VXE01_000809"
     CDS             11259..13076
                     /locus_tag="VXE01_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0749755.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13229..14380
                     /gene="nagA"
                     /locus_tag="VXE01_000810"
     CDS             13229..14380
                     /gene="nagA"
                     /locus_tag="VXE01_000810"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV0749756.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPYTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14543..15601
                     /locus_tag="VXE01_000811"
     CDS             14543..15601
                     /locus_tag="VXE01_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0749757.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15752..16117
                     /locus_tag="VXE01_000812"
     CDS             15752..16117
                     /locus_tag="VXE01_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV0749758.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16193..17134
                     /locus_tag="VXE01_000813"
     CDS             16193..17134
                     /locus_tag="VXE01_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV0749759.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     KDYQEHQPTSWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17082..18098
                     /locus_tag="VXE01_000814"
     CDS             17082..18098
                     /locus_tag="VXE01_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV0749760.1"
                     /translation="MDISQVFRLKRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRTGLSQGKSFSEIMASLGFSSAIVTQLSLAEVHGNLHLSLRKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGFVSVGVLLALTFYKRSSKMRVFSILARIPFLGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQIMQEQGSQLFKEIGQDLAQSLQNGREFSQTIGTYPFFKKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18100..18426
                     /gene="comGC"
                     /locus_tag="VXE01_000815"
     CDS             18100..18426
                     /gene="comGC"
                     /locus_tag="VXE01_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV0749761.1"
                     /translation="MKKMMTLLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQAKAYKEYHDKNGGA
                     NRKVND"
     gene            18419..18823
                     /locus_tag="VXE01_000816"
     CDS             18419..18823
                     /locus_tag="VXE01_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV0749762.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18828..19088
                     /locus_tag="VXE01_000817"
     CDS             18828..19088
                     /locus_tag="VXE01_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749763.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19051..19512
                     /locus_tag="VXE01_000818"
     CDS             19051..19512
                     /locus_tag="VXE01_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0749764.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            19490..19900
                     /locus_tag="VXE01_000819"
     CDS             19490..19900
                     /locus_tag="VXE01_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0749765.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKSEEKPEKKENS"
     gene            20037..20631
                     /locus_tag="VXE01_000820"
                     /pseudo
     CDS             20037..20631
                     /locus_tag="VXE01_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20692..21645
                     /locus_tag="VXE01_000821"
     CDS             20692..21645
                     /locus_tag="VXE01_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0749766.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21696..22886
                     /locus_tag="VXE01_000822"
     CDS             21696..22886
                     /locus_tag="VXE01_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV0749767.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSIPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23034..23405
                     /gene="rnpA"
                     /locus_tag="VXE01_000823"
     CDS             23034..23405
                     /gene="rnpA"
                     /locus_tag="VXE01_000823"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV0749768.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23380..24204
                     /locus_tag="VXE01_000824"
     CDS             23380..24204
                     /locus_tag="VXE01_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0749769.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24223..25209
                     /locus_tag="VXE01_000825"
     CDS             24223..25209
                     /locus_tag="VXE01_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV0749770.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25260..25883
                     /locus_tag="VXE01_000826"
     CDS             25260..25883
                     /locus_tag="VXE01_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV0749771.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26014..27471
                     /locus_tag="VXE01_000827"
     CDS             26014..27471
                     /locus_tag="VXE01_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0749772.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27494..27775
                     /locus_tag="VXE01_000828"
     CDS             27494..27775
                     /locus_tag="VXE01_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0749773.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27852..28337
                     /locus_tag="VXE01_000829"
     CDS             27852..28337
                     /locus_tag="VXE01_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0749774.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28354..29019
                     /locus_tag="VXE01_000830"
     CDS             28354..29019
                     /locus_tag="VXE01_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV0749775.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            29023..29886
                     /locus_tag="VXE01_000831"
     CDS             29023..29886
                     /locus_tag="VXE01_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV0749776.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTEN
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29888..30592
                     /locus_tag="VXE01_000832"
     CDS             29888..30592
                     /locus_tag="VXE01_000832"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV0749777.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVTYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30771..32444
                     /locus_tag="VXE01_000833"
     CDS             30771..32444
                     /locus_tag="VXE01_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0749778.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQFLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKSLLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNESKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32556..33647
                     /gene="ulaG"
                     /locus_tag="VXE01_000834"
     CDS             32556..33647
                     /gene="ulaG"
                     /locus_tag="VXE01_000834"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV0749779.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33761..35737
                     /gene="tkt"
                     /locus_tag="VXE01_000835"
     CDS             33761..35737
                     /gene="tkt"
                     /locus_tag="VXE01_000835"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0749780.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35854..36153
                     /gene="yajC"
                     /locus_tag="VXE01_000836"
     CDS             35854..36153
                     /gene="yajC"
                     /locus_tag="VXE01_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0749781.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36200..36628
                     /locus_tag="VXE01_000837"
     CDS             36200..36628
                     /locus_tag="VXE01_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV0749782.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLCQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36630..37040
                     /locus_tag="VXE01_000838"
     CDS             36630..37040
                     /locus_tag="VXE01_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749783.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37340..39991
                     /gene="adhE"
                     /locus_tag="VXE01_000839"
                     /gene_synonym="adhC"
     CDS             37340..39991
                     /gene="adhE"
                     /locus_tag="VXE01_000839"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV0749784.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12209 a         7222 c         9053 g        11778 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaaac tattttggag gattacccaa gtccggctga agggaacggt
      301 cttgaaaacc gtcaggcgtg taaaagcgtg cgtgggttcg aatcccacat cctcctttta
      361 tattaacgcg ggatggagca gctcggtagc tcgtcgggct cataacccga aggtcgtagg
      421 ttcaaatcct gctcccgcaa taaggctcgg tagctcagtt ggtagagcaa tggattgaag
      481 ctccatgtgt cggcggttcg attccgtctc gcgccattta tatattttgg aagggtagcg
      541 aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg gttcgggggt tcgaatccct
      601 ccccttccat tttacgggca tagtttaaag gtagaactaa ggtctccaaa accttcagtg
      661 tgggttcaat tcctactgcc cgtgttaata gaattatggc gggtgtggtg aagtggttaa
      721 cacaccagat tgtggctctg gcatgcgtgg gttcgatccc catcactcgc ctattttata
      781 ttggggtata gccaagcggt aaggcaaggg actttgactc cctcatgcgt tggttcgaat
      841 ccagctaccc cagttactat ttgccggcgt ggcggaattg gcagacgcgc tggactcaaa
      901 atccagtgtc cgcaaggacg tgccggttcg accccggccg ccggtatagt atagtgttag
      961 gaacgttgtt attcttcgtt ccttttttat attatttttg gtataattat agttattcaa
     1021 attttgttta gattgagaaa gtgtagggta gtatgtcttg ttctatcgat ttattaaaac
     1081 atcggtattt gaaaaatatt aaagaaaatc ctgaattgtt tgtcggaatt gagttggagt
     1141 atcctgttgc aagtttagaa ggggatgcta cagatgttga agttataaag gatctatttc
     1201 attatttagt ttctactttg gatctcaccg tagcaaaggt agatgatttt ggcaatctga
     1261 tccagttagt agatccgata agtcaggatg ctattttatt tgaagtttcc tatacaacga
     1321 ttgagtttgc atttggtaag gctgaaacga ttcaagaggt cgaaaatcgt ttcaataatt
     1381 atatgaatgt aattcagaga aagttagctg aatcaaatca tgctattgtt ggctgtggta
     1441 tccatcccaa ctgggataaa aatgagaatt gtccagtggc ttatccacgc tatcagatgt
     1501 tgatggatta tttgaatttg agtagaaata ttattaaatc agatttacat catttccctg
     1561 aatatggtac ttttatctgt gggagccagg ttcagctgga tatttcaaaa accaactact
     1621 tacgggtgat taatgctttt actcaaattg aagcggctaa ggcttattta tttgcaaact
     1681 ctgaattttc gggtgcggat tgggatacga aaatttcaag ggatattttc tgggaagaat
     1741 ctatgcatgg tatctatcca gagaatgttg gggtcaatgc tagactcctt aatgatgaag
     1801 ctgatttttt tgactatcta aatcattctg cgatttttac tgcggaacgt gatgggcaga
     1861 cctattattt ttatcctatt caggctgggg actatttggc tacgcctgaa atccaagcat
     1921 tttctctgaa tggggatgag gttattattt ccccccaaga gaaggatttt gaaactcatc
     1981 gtagttacca gtaccaagac ttaacgactc gaggaacagt tgagtttcgt agtgtgtgta
     2041 cacagccact tgatagaact tttgcttctg cagcttttca cttgggatta ttggttaatt
     2101 tagacaagtt agaagcttac ttagaaacag cacctttctt taaagtattt ggttatgatt
     2161 acaagtcttt aaggagacaa ttttctaaga aaaatcttac agatgaggaa gaaactacga
     2221 ttattgaatt ttccaaagac ttactcctac tagctgagga gggactagtg gtgagaaata
     2281 aggaagaaat gacctattta cagcctttga gagaagaatt gagcctataa tttctcttat
     2341 aaagggagaa ttttctgaaa aatcatgata taatggacga gactatagat aaaggataga
     2401 gagtaatgac attagtttat caatcaacgc gtgatgccaa caatacagta actgccagcc
     2461 aagcaatttt gcaaggttta gcgacggacg gcggtttgtt tacaccggtt acttatccaa
     2521 aggtagattt gaactttgac aaattgaaag atgcttctta ccaggaagtt gctaagctag
     2581 ttttgtcagc atttttagat gactttacag ttgaggagtt ggactactgt atcaacaatg
     2641 cctacgatag caaatttgat actccagcta ttgcaccatt agtgaaatta gatgggcaat
     2701 acaatttgga acttttccat ggttcaacga ttgcctttaa ggatatggcc ttgtctattt
     2761 tgccatactt tatgacgact gctgctaaga aacatggttt ggagaacaag attgttatct
     2821 tgacagcgac atctggtgac acggggaaag ctgctatggc ggggtttgcg gatgtgcctg
     2881 gtactgagat tatcgtcttt tatccaaagg atggtgtcag caagattcaa gagttacaaa
     2941 tgaccactca gactggcgac aatactcatg ttattgctat tgatggtaac tttgacgatg
     3001 cgcaaacaaa tgtgaagcac atgtttaacg atgtggctct tcgtgaaaaa ttgactacca
     3061 acaagttgca attttcatca gctaactcta tgaacattgg tcgtctggtg ccacaaattg
     3121 tttattatgt ttatgcctac gctcaattgg ttaagactgg tgaaattgta gctggtgaaa
     3181 agattaactt cacagtacca acaggaaact ttggaaatat cttggctgcc ttttatgcca
     3241 aacaaatcgg cctaccagtt ggcaagctaa tctgtgcttc aaatgacaac aatgttttga
     3301 cagacttctt taaaacacgt gtctatgaca aaaaacgtga gtttaaggta acaaccagcc
     3361 catctatgga tatcttggta tcttcaaact tggagcgctt gattttccat cttttgggaa
     3421 ataatgctga aaagacagct gaacttatga atgccttgaa cacgcaagga caatataagt
     3481 tgacagactt tgatgcagag attttggacc tctttgcagc tgaatatgcg actgaggaag
     3541 aaacagcggc agaaatcaag cgtgtttatg agtcagattc ttatattgag gatccacata
     3601 cggcggttgc ctcagcagtt tatagaaaat accaagcggt tactgatgat gcgactaaga
     3661 cagtgattgc ttcaacagct agtccataca agttcccagt agttgcagta gaagctgtaa
     3721 ctggaaaagc aggtttaaca gactttgaag ccttggctca attacatgaa atctcaggcg
     3781 ttgcagtgcc accagcagtt gatgggcttg aaatagctcc aattcgtcac aagacaacag
     3841 tggcagctgc tgacatgcaa gcagcggttg aggcttattt aggactttaa gacagaggga
     3901 gcaaactcgg ttgggaaacc aactgagttt cttttcatca ggaggagaga ttgtttaaga
     3961 aaaataaaga cattcttaat attgcattgc cagctatggg tgaaaacttt ttgcagatgc
     4021 taatgggaat ggtggacagt tatttggttg ctcatttagg attgatagct atttcagggg
     4081 tttcagtagc tggtaatatt atcaccattt atcaggcgat cttcatcgct ctgggagctg
     4141 ctatttccag tgttatttca aaaagcatag ggcagaaaga ccagtcgaag ttggcctatc
     4201 atgtgactga ggcgttgaag attaccttac tattaagttt ccttttagga tttttgtcca
     4261 tcttcgctgg gaaagagatg ataggacttt tggggacgga gagggatgta gctgagagtg
     4321 gtggactgta tctatctttg gtaggcggat cgattgttct cttaggttta atgactagtt
     4381 tgggagcctt gattcgtgca acgcataatc cacgtctgcc tctctatgtt agttttttat
     4441 ccaatgcctt gaatattctt ttttcaagtc tagctatttt tgttctggat atggggataa
     4501 ctggtgttgc ttgggggaca attctgtctc gtttggttgg tcttgtgatt ttgtggtcac
     4561 aattaaaact gccttatggg aagctaactt ttggtttaga taaggaactg ttgaccttgg
     4621 ctttaccagc agctggagag cgacttatga tgagggctgg agatgtagtg atcattgcct
     4681 tggtcgtttc ttttgggacg gaggcagttg ctgggaatgc aatcggagaa gtcttgaccc
     4741 agtttaacta tatgcctgcc tttggcgtcg ctacggcaac ggtcatgctg ttggcccgag
     4801 cagttggaga ggatgattgg aaaagagttg ctagtttgag taaacaaacc ttttggcttt
     4861 ctctgttcct catgttaccc ctgtccttta gtatatatgt cttgggtgta ccattaactc
     4921 atctctatac gactgattct ctagcggttg aggctagtgt tctagtgaca ctgttttcac
     4981 tacttggaac ccctatgacg acaggaacag tcatctatac ggcagtctgg cagggattag
     5041 gaaatgcacg cctccctttt tatgcgacaa gtataggcat gtggtgtatc cgcattggaa
     5101 caggatatct gatggggatt gtgcttggtt ggggcttacc tggtatttgg gcagggtctc
     5161 tcttggataa tggttttcgc tggttatttc tacgctatcg ttaccagcgc tatatgatct
     5221 tgaaaggata ggaaatgcaa aaaacagctt ttatttggga tttagacggg actttattgg
     5281 actcttacga agcgatttta tcagggattg aggagacttt tgctcagttt tctattcctt
     5341 atgataagga gaaggtgaga gagtttatct tcaagtattc ggtgcaagat ttgcttgtgc
     5401 gggtggcaga agatagaaat ctggatgttg aggtgctaaa tcaggtgcgt gcccagagtc
     5461 tggctgagaa gaatgctcag gtagttttga tgccaggtgc gcgtgaggtg ctagcttggg
     5521 cagacgaatc aggaattcag cagtttatat atactcataa ggggaacaac gcttttacca
     5581 ttctcaagga cttgggggtg gaatcctatt ttacagagat tttaaccagt cagagtggct
     5641 ttgtgcggaa gccaagtcca gaagcggcta cctatctgct agataagtat cagttgaatt
     5701 ctgataatac ttattatata ggggatcgga ctctggatgt ggaatttgcc cagaatagtg
     5761 ggattcaaag tatcaacttt ttagagtcta cttatgaagg gaatcacagg attcaagcgt
     5821 tagcagatat ttcccgtatt tttgagacta agtgataaaa agattgtgtc agttttgtga
     5881 cagagaccta acaaactatt tcaagtaatc gagtttgtta caaggaatag acagttctgt
     5941 taaataggcc cgagagggct ttttttctac attttttgtg ttatcataga caggtactca
     6001 tttgaaagga atttgaaaga atgaagaaaa gaatgttatt agcgtcaaca gtggccttgt
     6061 catttgcccc agtattggca actcaagcag aagaagtttt ttggactgca cgtagtgttg
     6121 agcaaatcca aaacgatttg actaaaacag acaacaaaac aagttataca gtacagtatg
     6181 gtgatacttt gagcaccatt gcagaagcct tgggtgtaga tgtcacagtg cttgcgaatc
     6241 tgaacaaaat cactaatatg gacttgattt tcccagaaac tgttttgaca acgactgtca
     6301 atgaagcaga agaagtaacg gaagttgaaa tccaaacacc tcaagcagat tctagtgaag
     6361 aagtgacaac tgcgacagca gatttgacaa ccaatcaagt gaccgttgat gatcaaactg
     6421 ttcaagttgc agatctttct caaccaattg cagaagctcc aaaagaagta gcatcaaatt
     6481 cagaagttgc agagacagtg actgctgcag aagaagtggc actatctaca gactctacta
     6541 cgccagaggg acaaccagcc gaaacaacta gtccagttga agaagcaact cctcaggaaa
     6601 cgactccagc tgagaagcag gaaacacaag caagccctca agctgcatca gcagtggaag
     6661 caactacaac aagttcagaa gcaaaagaag tagcatcatc aaatggagct acagcagcag
     6721 tttctactta tcaaccagaa gagacgaaaa taatttcaac aacttacgag gctccagctg
     6781 cgcccgatta tgctggactt gcagtagcaa aatctgaaaa tgcaggtctt caaccacaaa
     6841 cagctgcctt taaagaagaa attgctaact tgtttggcat tacatccttt agtggttatc
     6901 gtccaggaga cagtggagat cacggaaaag gtttggctat cgattttatg gtaccagaac
     6961 gttcagaatt aggggataag attgcggaat atgctattca aaacatggcc agccgtggca
     7021 ttagttacat catctggaaa caacgtttct atgctccatt cgatagcaaa tatgggccag
     7081 ctaacacttg gaatccaatg ccagaccgtg gtagtgtgac agaaaatcac tatgaccacg
     7141 ttcacgtttc aatgaatgga taaacccgac ttggtaacat cattttgacg aatgagatct
     7201 agctttcgtg ataggaagcg attctcgttc gttttttctt tgtcatactc ttcgaaaatc
     7261 tcttcaaacc acgtcagttt tatctgaaac ctcaaagctg tgctttgagc aacctgcgac
     7321 tagctttcta gtttactctt tgattttcat tgagtatcaa tttgaatgga aaatggaaag
     7381 ttattatctt gtaataatcc aagcaacatt cttgcaatct attttacttt atatcacaat
     7441 tgattggtca actattgata agtcaatgga taggaggaag aaatgataga gattcaagat
     7501 ttactgtatc aactccgctt gtctgagcaa gcgagtacgc aattgtttga aaaaggcttg
     7561 ggattagttt gacacggtat cagattttac tgtttttgct ggagcattct ccttgtaacc
     7621 aaatggcggt tcaggagcgt ttgaaaattg atcaggctgc tttgacacgg catttcaaga
     7681 ttttggaaac ggaaggtttg gtggagcgtc atcgtaatcc tgaaaatcag cgggaagtgt
     7741 tggtagaggc tgcgaagtat gccaaggagc agttagtggt gaatccccct ctgcaacata
     7801 tcaaggttaa ggaagagatg gaaagtatct taacagagtt tgagagaaca gaactcagcc
     7861 gtttattaaa taaattggtt ttgggtattg aaaatataga aatttaagga gaaatagatg
     7921 tcaattattt taacaacgat cgttgctttg gagcattttt acatttttta tttggaaagt
     7981 attgccacgc aatcagatgc gactagtcgt gtatttaata tggaaaagga agaattggct
     8041 catccgtcag taagttcatt gttcaaaaat caaggaattt ataaggctct gctaggagtc
     8101 tttctcttgt atgtcattta tttctcacag aatttagaaa ttgtgactat ttttgtctta
     8161 tttgtgattg gtgctgcgac ttacggctct ttaacagcgg ataaaaaatt attttgaagc
     8221 aaggtggatc agctattttg gccttgatta gtattttact ctttaaatac acttgaaggt
     8281 tgattctaat ctcgctaatc ctttttaatc cagaataagg gaaatatgtt atacttgttt
     8341 ttaagaaaaa agtctcattg aattggtttt gaggagttag aaatgaaagt attagtgaca
     8401 ggttttgagc ccttttgagg ccattaaagg tttaccagct gaaatccatg gtgctgaggt
     8461 ccgttagcta gaggtgccga cagtttttca caaatctgct caagtattgg aagaagagat
     8521 gaatcgttat caacctgact ttgtcctttg tattgggcaa gctggtggaa gaactagttt
     8581 gacacctgaa cgagtggcca ttaatcaaga cgatgcacgc atttctgata acgaagataa
     8641 tcaaccgatt gaccgtccca ttcgcccaga tggtgcttcg gcctacttta gtagtttgcc
     8701 gattaaagcg atggttcaag atataaaaaa agagggctta ccggcctctg tttccaatac
     8761 ggcagggact tttgtctgca gccatttgat gtatcaggct ctctatttgg tagaaaagaa
     8821 atttccatat gttaaggcag gttttatgca tattccttat atgatggaac aggtggtgaa
     8881 cagaccgact actccaacta tgagtttagt ggatattcgg cgagggatag aagcagcaat
     8941 cggcgctatg atagaacatg gagatcagga actcaagttg gtaggcggag aaactcattg
     9001 atagaaaaaa gcttgagggg aaaaaccttc aagcttttgg acgttttcga gccaatactg
     9061 ctcggtaaaa cataatttta gtgcattgga tataaggtag gagtgaaaaa ctagcaatgc
     9121 caaaggtaat ccaattgagg aagtaccaag gaagaagctg taaatctagg acaaagtgct
     9181 ggaacttgta gcccttcata aaggaacggc tagtttttag gattcgtctt ggtgggacct
     9241 gtcctaggtc tagactataa cagagaagaa attccacctg tgaataggca taatactgtg
     9301 gaatatagag gatatttcct acaatgatca agatgagact tgcaagaaag tagagtccaa
     9361 agaccatgag gaaacgctcg gtttcaactg atgagagatc tagatttgga aactcaggat
     9421 gtagggtgac gaattttttg gctaaaaagc tactataaaa gaggaggtaa atcccaagta
     9481 aattagggat actccataaa aagagataga aacgtttgag aagtagggtc aaaaaggttt
     9541 gagaaaagcg ctcctcatca aagagagcta ggctgttttt tacagatggc tccgttttag
     9601 aatctttcat gagtgtcagt gttgcataga cggaactggt caaaagaata gtcccgataa
     9661 aggagactag tagaggaaag aggtaggctt gaagtatttg gccaagtatg ctgaaaaatg
     9721 gctgttctaa aacagtcccg tggatccgag ataagggatt aagaaaacta gataagatga
     9781 ccagcatact gggaaggata tagaggagaa agagacgggg ggtgtcagcc tgaaaatgtt
     9841 ttgactcctg acgaattgtt tttaaatcaa tttttggata gttcattctc ttattatacc
     9901 atagttctta tacatagttc gtgacagttc ctactttttt tgataaaatc atacagtgtg
     9961 tccttgggca cactgtatga actgggactg tctttcccag cttcggaggt aaaaaatgtc
    10021 agattcacca atcaaatatc gtttgattaa gaaagaaaaa cacacaggag ctcgtctggg
    10081 agaaatcatc actccccacg gtacctttcc gacacctatg tttatgccag ttgggacaca
    10141 agccactgtc aaaactcagt cacctgaaga attgaaggag atgggttcgg gaattatcct
    10201 atcaaacacc tatcatctct ggcttcgccc tggagatgaa ctcattgcac gcgctggtgg
    10261 tctccacaag ttcatgaatt gggaccagcc tatcttgaca gatagtggtg gttttcaggt
    10321 ttattcttta gcagatagcc gtaatatcac agaagaagga gtaaccttta aaaatcatct
    10381 aaatggttct aagatgttcc tatccccaga aaaagccatc tctattcaga ataatctggg
    10441 ttcagatatc atgatgtcct ttgatgaatg tcctcagttt tatcaacctt atgactacgt
    10501 taagaaatcg atcgagcgta ccagccgttg ggctgagcgt ggtttgaagg ctcaccgtcg
    10561 tccacatgac caaggtttgt ttggaattgt gcaaggtgca ggatttgaag accttcgccg
    10621 ccaatcagct catgatcttg tcagcatgga tttctcaggc tactctatcg gtggtttggc
    10681 agtgggagaa acccatgaag agatgaatgc ggtcttggac tttacaactc aactgctacc
    10741 tgaaaataaa cctcgttatc tgatgggtgt gggagcgcca gatagcttga tcgatggggt
    10801 cattcgtggg gtggatatgt ttgactgtgt cttaccgact cgaattgctc gtaacgggac
    10861 ttgtatgacc agtcaaggac gtttggttgt gaaaaatgcc cagtttgctg aggactttac
    10921 gccactggat cctgagtgtg attgctacac atgtaataac tatacacgcg cttaccttcg
    10981 tcacctgctc aaggctgatg aaacctttgg tatccgcttg actagctacc acaatcttta
    11041 cttcttgctt aacttgatga agcaagtgcg acaagccatc atggatgaca atctcttgga
    11101 attccgtgag tattttgtgg aaaaatatgg ctataataag tcaggacgta atttttaaaa
    11161 tggaattgat ataagctaaa aatcctaagt tttctcttag gatttttctt ctttttttga
    11221 tagaataaag tgtacaatga aaggaagaat aaactcgtat gcgcattaaa tggttttcct
    11281 tgattaggat tataggttta cttttggtac tcttgtatca cttctttcag acgatctttc
    11341 ctggaggatt tttcggggta gatgtctttt tcacattttc aggtttcctg attacagctc
    11401 tactcattga agaattttct aagaacaatg agattgattt gataggattt tttagaagac
    11461 gcttttatcg gattgtgcca cctgtggttt tgatggtctt ggtgaccatg ccttttactt
    11521 tcttggttcg ccaagactat gttgctggaa ttggtggcca gattgcgagc gtcttaggct
    11581 ttatgaccaa cttctatgaa ctcctaacag gtgggagtta tgaatctcag ttcattcctc
    11641 atttgtttgt tcataattgg agtttggcag ttgaggttca ctactatatt ctttggggat
    11701 tggcagtttg gttcttatcc aaacaagcta aatcaaatgg tcagttgaag gggatggtct
    11761 ttctcttatc tgctgttgcc ttcttgatca gtttcttctc catgtttatt ggtagttttc
    11821 tagtgacctc ttattcctct gtttatttct ccagtttaac tcatgtctat ccattctttt
    11881 taggaagtat gttagcaact attgtaggcg ttcgtcagac gacttccctc gtcaagcagt
    11941 tggataaaat ctgggattta cgaaagactt tggtagtttt tggaggaggc tttggtttcc
    12001 tagttctttt gactttcttt gtcaaattca cttatctttt tgcctatctt atcggcttct
    12061 tacttgccag tcttgcagct cttgccatga ttctggcggc gcgtgtctta catgaaaaga
    12121 cacatcatat acaggagccg aagattatca gctttttagc ggatactagc tatgcggttt
    12181 atcttttcca ttggcctttc tatatcattt tctcacagtt gacatcaaat cttcttgctg
    12241 tattactgac tctgatttgt tcttatggct ttgccagtct gtcattttat gtattggaac
    12301 cttggattgc aggcaagaac acacctattt tacaaactct tcgtcccctg ccttatattc
    12361 acgcaattct tgcagcaggt acaggaatct tgaccttcat tgtctgcatg gtgaccttgt
    12421 tggcaccaca agtgggagcg tttgagacag acttgactgt caatggcttg aagcaagctg
    12481 caacaaatat tggccagacc aaggtgatgg cagaacgggc agatgcaaac agtttgggaa
    12541 ttgctgatgg cactatgtta attggtgact cagtggcttt aagggcaaat acagcactac
    12601 agacagctct tcctggagca cagattaacg cgcaggtcag cgtaacaacc aagaccgcaa
    12661 atgaaatcat gctaaataat agccagaata aatttttacc taagacggtg gtcattgcga
    12721 ctggggtaaa taatcctgag aattacaagg atgactggga cagtatcgtg aaaaatcttc
    12781 ctaagggaca ccatatgatt ttggtgactc cttatgaggg agataagaca aaagagacct
    12841 atgccatcgt tgagaaggct gctgcctata tgagagaatt ggcagagaag acaccttaca
    12901 ttacgatagc agattggaat caagttgcga aagagcatcc agaaatttgg gcaggaacag
    12961 accaggttca tttcgggagt gagagtagca ctatcgaagc aggagcaaaa ttgtatgcag
    13021 atacgattgc cacagctttg cagacagctc aagataagcc ggttaaatca aaataacttg
    13081 tattaaaaaa gagaagagtt ggagaaatcc agctctttta aaatatctcc aaaaaatagg
    13141 tctataccat ttacaaataa aaaagaaagg tttataatgt aattgacata ataaattgta
    13201 gaatcaatct tttaaggagg ttaacattat gcctaactat attaaagcgg atcagttttt
    13261 ctacccacac ggagttcgtc gaggtggtta cttggaactt gtggacggca agtttgggaa
    13321 acatgtagag cagattcctg aaggggctga ggtgattgac tatacaggtt atagcattgc
    13381 cccaggtctt gtggatactc atattcatgg atatgcaggt gtagatgtga tggacaacaa
    13441 cattgaaggt acattgcata ctatgagtga aggacttctt agtaccggtg ttaccagttt
    13501 cttacccaca actttaacag ccacttatga gcaattgctt gcagtcactg aaaatcttgg
    13561 aaaccattat aaagaagcaa caggtgctaa gattcgtggg atttattatg aaggtccata
    13621 tttcacagaa acttttaagg gggcacaaaa tccaacttat atgagagacc cgggtgttga
    13681 ggagtttcat tcttggcaaa aagcggcaaa tggcttgctt aataaaattg cccttgcacc
    13741 agaacgtgat ggggtggaag actttgttcg tacagttacg ggcgaaggtg tgacggttgc
    13801 tcttggacat tcaaacgcga cttttgatga agccaaaaaa gcagtcgatg ctggagcgag
    13861 tgtttgggtg catgcctaca atggaatgcg tgggttgact caccgtgaat tgggtatggt
    13921 tggagccatg taccaattgc catataccta tgcagagttg atctgtgatg gtcaccacgt
    13981 agatccaaag gcttgcgaaa ttcttatcaa acaaaaagga acagaaaaca tcgctcttat
    14041 cacagactgt atgacagctg ggggattgga agacggagat tatatgttgg gagaattccc
    14101 agttgtcgtt gcaaatggaa ctgcacgcct caaatcgaca ggtaacttgg caggttctat
    14161 cctcaaactc aaagatggtt tgaagaatgt ggtcgaatgg ggaattgcga atccgcatga
    14221 agcagtcatg atggccagct tcaacccagc taaatccgtt cacatcgatg acgtctgtgg
    14281 ccaaatccgt gaaggctacg acgctgactt catcgtatta gataaagatt tggaattggt
    14341 agcaacctac ctagatggtg tgaaacgtta tcaagcataa gagagaaggc agaagttaga
    14401 gactagcttc tgctttttta tacagggtac tttactggta aataaaaagt taaaaaaatc
    14461 acaaaaaaag cttgaagaaa caaagaaaaa ggcttacaat tgaactataa atattacaaa
    14521 taaaaaaacg gaggagtgct ttatgaaagc ctatacttat gttaaaccag gacttgcttc
    14581 ttttgttgat gtagacaaac cagttattcg caagccaaca gatgctattg tgcgtattgt
    14641 aaaaaccact atttgtggaa cagacctcca tattatcaaa ggggatgttc ctacttgcca
    14701 aagtggtacc attcttggcc acgaagggat tgggattgtt gaagaagttg gggaaggagt
    14761 ttccaacttc aaaaaaggtg acaaggtctt gatttcttgc gtctgtgcct gtggtaaatg
    14821 ctactactgt aaaaaaggaa tttatgccca ctgtgaagac gaagggggct ggattttcgg
    14881 tcacttgatt gatggtatgc aggctgaata tctacgtgtc cctcatgcag ataatactct
    14941 ttaccatact ccagaagact tgtcagatga agctttggtt atgctgtcag acattctgcc
    15001 tactggatat gaaattggtg tcttaaaagg gaaagtagaa cctggttgca gcgtagccat
    15061 tattggttca ggtccagttg gattggctgc tcttttaaca gcccaattct attcaccagc
    15121 taaattgatt atggtagacc tagacgataa ccgcttggaa actgccctat cattcggtgc
    15181 gactcataag gttaattctt cagaccctga aaaagccatt aaagaaattt atgatttgac
    15241 agatggtcgt ggtgtggatg tcgctatcga agctgttggt attcctgcaa catttgattt
    15301 ctgtcaaaag attatcggtg tagacggaac ggttgccaac tgtggtgtgc atggtaaacc
    15361 agttgaattc gatttagata aactttggat tcgcaacatc aatgtaacaa ctggtttggt
    15421 atctacaaat acgactccac aattgttgaa agcacttgaa agtcataaga ttgaaccaga
    15481 aaaattggta actcactatt tcaaactcag tgaaattgaa aaagcctatg aagtcttcag
    15541 taaggcagca gaccaccatg ccattaaggt cattatcgaa aacgatatct cagaagccta
    15601 agtagtaaaa atatttttgt acataagtaa atagaaattc agtcatccat cagatggctg
    15661 gattttttat caaaaaatta agaaatgagc atatttcttt ccttgtctgg cggaattggt
    15721 tataatatac ggtacaaagg aatgaatgaa tatgtatcgt gttatagaaa tgtacggaga
    15781 ttttgaaccg tggtggttct tagaaggttg ggaagaagat attgtagcaa gtagaaaatt
    15841 tgaccagtat tatgatgctc tcaaatacta caaaacttgc tggtttagat tggaacaaga
    15901 atcccctctt tataaaagta gaagcgactt gatgaccatt ttttgggacc cggaagacca
    15961 acgctggtgt gatgaatgtg atgagtattt acaacaatac cattctttgg ctcttttgca
    16021 ggatgagcag gttatcccag acgaaaaact acgctcaggc tatgaaaaac aaaccagtca
    16081 ggaaaggaat cgttcttgcc gtatgaaatt aaaatagaga aaagtaactt ttttggagtt
    16141 gcttttttta tttttctaac gctttgcgaa tagtataggt gaggaggtaa gtatggttca
    16201 agaaattgca caagaaatca ttcgttcagc tcggaaaaaa gggacgcagg atatttattt
    16261 tgtccctaag ttagacgcct atgagcttca tatgagggta ggagacgagc gctgtaaaat
    16321 tggtagctat gattttgaaa agtttgcagc cgttatcagt cactttaagt ttgtggcggg
    16381 tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc tgtgattatg cctatgacca
    16441 gaagatggcg tctctacgtt tatctactgt aggcgattat cggggacatg agagtttggt
    16501 tatccgtttg ttgcacgatg aggagcagga cttgcatttt tggtttcagg atattgaaga
    16561 attaggcaag cagtacaggc aacggggact ctatcttttt gctggcccgg ttgggagtgg
    16621 taagacgacc ttgatgcatg aattgtccaa gtcactcttt aaaggacagc aagttatgtc
    16681 catcgaagat cctgtcgaaa tcaagcagga cgacatgctt cagttgcagt tgaacgaagc
    16741 aatcggccta acctatgaaa atctaatcaa actttccttg cgtcatcgac cagacctcct
    16801 gattatcgga gaaattcgag acagcgagac ggcgcgtgca gtagttagag ctagtctgac
    16861 aggtgcgaca gtcttttcaa ccattcatgc caagagtatt cgaggtgttt atgagcgcct
    16921 gctggagttg ggtgtgagtg aggaggaatt ggcagtcgtt ctgcaaggag tctgctatca
    16981 gagattaatc gggggaggag gaatcgttga ctttgcaaac aaagactatc aagaacacca
    17041 gccaactagc tggaatgaac agattgacca gcttcttaaa gatggacata tcacaagtct
    17101 tcaggctgaa acggaaaaaa ttagctacag ctaagcaaaa aaatatcatc accttgttta
    17161 acaatctctt ttccagcggt tttcatctgg tggagaccat ctccttttta gataggagtg
    17221 ctttgttgga caagcagtgt gtgacccaga tgcgcacggg cttgtctcag gggaaatcat
    17281 tctcagaaat aatggctagt ttgggctttt caagtgccat tgtcactcag ttatccctag
    17341 cggaagtcca tggaaatctc cacctgagtt tgagaaagat agaagagtat ctagacaatc
    17401 tggccaaggt caagaaaaaa ctaattgaag tagcgaccta tcccttgatt ttgctgggtt
    17461 ttcttctctt aatcatgctg ggactacgga actatctact accacaactg gatagtagta
    17521 atattgccac tcagattatc ggtaatctgc cacaaatctt tctaggaatg gtaggatttg
    17581 tttcagtagg tgtcctttta gcactcactt tttataaaag aagttctaag atgcgcgtct
    17641 tttctatcct agcacgcatt ccttttcttg gaatctttgt gcagacttat ctgacagctt
    17701 attatgcgcg tgaatggggt aatatgattt cgcaggggat ggaactgacg cagatttttc
    17761 agatcatgca ggaacaaggt tcccagctct ttaaagaaat cggtcaagat ttggctcagt
    17821 ccctacaaaa tggccgtgaa ttttctcaga cgataggaac ctatcctttc tttaaaaagg
    17881 agttgagtct catcatcgag tatggggaag tcaagtccaa gctgggtagt gagttggaaa
    17941 tctatgctga aaaaacttgg gaagcctttt ttacccgagt caaccgcacc atgaatctgg
    18001 tgcagccact ggtctttatc tttgtggctc tgattattgt tttactttat gcggcaatgc
    18061 tcatgcccat gtatcaaaat atggaggtga atttttaaca tgaaaaaaat gatgacatta
    18121 ttgaaaaaag cgaaggttaa agcttttaca cttgtggaaa tgttggtggt cttgctgatt
    18181 atcagcgtgc ttttcttgct ctttgtacct aatctgacca agcaaaaaga agcagtcaat
    18241 gacaaaggaa aagcagctgt tgttaaggtg gtggaaagcc aggcagaact ttatagctta
    18301 gaaaagaatg aagatgctag cctaagaaag ttacaagcag atggacgcat cacggaagaa
    18361 caggctaaag cttataaaga ataccatgat aaaaatggag gagcaaatcg taaagtcaat
    18421 gattaaggcc tttaccatgc tggaaagtct cttggttttg ggtcttgtga gtatccttgc
    18481 cttgggcttg tccggctctg ttcagtccac ttttgcggcg gtagaggaac agattttctt
    18541 tatggagttt gaagaactct atcgggaaac ccaaaaacgc agtgtagcca gtcagcaaaa
    18601 gactaatcta aatttagatg ggcagacgct tagcaatggc agtcaaaagt tgacagttcc
    18661 taaaggaatt caggcaccat caggccaaag tattacattt gaccgagctg ggggcaattc
    18721 gtccctggct aaggttgaat ttcagaccag taaaggagcg attcgctatc aattatatct
    18781 aggaaatgga aaaattaaac gcattaagga aacaaaaaat tagggcagtg attttactgg
    18841 aagcagtagt cgctctagct atctttgcca gcattgcgac cctccttttg ggacaaattc
    18901 aaaaaaatag gcaagaggaa gcaaaaatct tgcaaaagga agaagtcttg agggtagcta
    18961 agatggccct gcagacgggg caaaatcagg taagcatcaa cggagttgag attcaggtat
    19021 tttctagtga aaaaggattg gaggtctacc atggttcaga acagttgttg gcaatcaaag
    19081 agccataagg tcaaggcttt taccttgtta gaatccctac ttgccctcat tgtcatcagt
    19141 gggggattac tcctttttca aactatgagt cagctcctca tttcagaagt tcgctaccag
    19201 caacaaagcg agcaaaagga gtggctcttg tttgtggacc aacttgaggc agaattagac
    19261 cgttcgcagt tcgaaaaagt agaaggcaat cgcctataca tgaagcaaga tggcaaggac
    19321 atcgccatcg gtaagtcaaa gtcagacgat tttcgtaaaa ccgatgctag tggacggggg
    19381 tatcagccta tggtttatgg cctcaaatca gctcagatta cagaggacaa tcaactggtt
    19441 cattttcgtt tccagtttca aaaaggctta gaaagggagt tcatctatcg tgtggaaaaa
    19501 gaaaaaagtt aaggcaggtg ttctcctcta cgcagtcacc atagcagcca tctttagtct
    19561 tttgttgcaa ttttacttga accgacaagt cgcccactat caagactatg ctttgaataa
    19621 agaaaaattg gttgcttttg caatggctaa acgaaccaag gataaagccg agcaagaaag
    19681 tggggaacag gtctttaatc taggtcaggt aagctatcaa aacaagaaaa caagcttggt
    19741 gacgactgtt cgtacgtcta agagccaata tgagtttctg tttccttcag tcaaaatcaa
    19801 agaagagaaa agagataaaa aggaagaggt agcgactgat tcaagcgaaa aagcggagaa
    19861 aaaatcagaa gagaagcctg aaaagaaaga gaattcatag tcaattcaac tataatgcgt
    19921 tgaatccaga atagtccact gtagtttcta gaaaattgct ggaaatggat gttaagctcc
    19981 aattcatttg tttatatctt atttcagttt actatacttt gtgctaaatt aaagatatga
    20041 aacatgattt taaccacaaa gcagaaactt tcgattcccc taaaaatatc ttcctcgcaa
    20101 acttggtatg tcaagcagcc gagaaacaga ttgatcttct atcagacaaa gaaattttag
    20161 atttcggtgg tggcacgggt ctattagcct tgcccctaac ccctagccaa gcaggctaag
    20221 tcagtcactc ttgtagacat ttctgagaaa atgttggagc aagctcgttt gaaagtggag
    20281 cagcaagcaa tcaagaatat ccagtttttg gagcaagatt taccgaaaaa tcccttggag
    20341 aaagagtttg attgccttgc tgttagtcgg gttcttcatc atatgcctga tttggatgcg
    20401 gctctctcac tgtttcatca acatttgaag gaagatggga aactcatcat tgctgatttt
    20461 accaagacag aagctaatca tcatggattt gatttagctg aactggaaaa caagctaatt
    20521 gagcatggtt tttcatctgt gcatagtcag attctctata gcgctgaaga cctgtttcaa
    20581 gggaatcact cagaattctt tttaacagta tcccaaaaat cactcgccta gtcagggagt
    20641 gatttttcta taaggatgga aaaaagaagg gaaatttgat aagataggaa tatggatttt
    20701 gaaaaaattg aacaagctta tatctattta ctagagaatg tccaagtcat ccaaagtgat
    20761 ttggcgacca acttttatga cgccttggtg gagcaaaata gcatctatct ggatggtgaa
    20821 actgagctaa accaggtcaa agacaacaat caggccctta agcgtttagc actacgcaaa
    20881 gaagaatggc tcaagaccta ccagtttctc ttgatgaagg ctgggcaaac agaacccttg
    20941 caggccaatc accagtttac gccagatgct attgccttac ttttggtatt tattgtggaa
    21001 gagttgttta cagaggagga aattactatc ctcgaaatgg gttctgggat gggaattcta
    21061 ggcgctactt tcttgacctc gcttgataaa aaggtggatt acttgggaat ggaagtggat
    21121 gatttgctga ttgatctggc agctagcatg gcagatgtaa ttggtttgca ggctggcttt
    21181 gtccaaggag atgccgttcg cccacaaatg ctcaaagaaa gcgatgtggt catcagtgac
    21241 ttgcctgttg gctattatcc tgatgatgcc gttgcgtcgc gccatcaagt tgcttctagc
    21301 caagaacata cttacgctca tcacttgctc atggaacaag ggtttaagta ccttaagtca
    21361 gatggatatg ctatttttct agctccgagt gatttgttga ccagtcctca aagtgatttg
    21421 ttgaaagtct ggttgaaaga ggaggcaagt ctggttgcta tgattagttt acctgaaaat
    21481 ctctttgcta atgctaaaca atctaagact atttttatcc tacagaagaa aagtgaaata
    21541 gcagtggagc cttttgttta tccacttgct agcttgcaag atgcaagtgt tttaatgaaa
    21601 tttaaagaaa attttcaaaa atggactcaa ggtactgaaa tataaaatag attttgttat
    21661 aatagttgaa aacgcttaaa aaggggtatc atgttatgac aaaaacaatt gcaatcaatg
    21721 caggaagttc aagtttgaaa tggcaattat acttaatgcc agaagaaaaa gtattggcga
    21781 aaggtttgat tgaacgtatc ggtttgaaag attcaatttc aactgtaaaa tttgacggcc
    21841 gttctgaaca acaaattttg gatattgaaa atcatataca agccgttaaa attttattgg
    21901 atgacttgat tcgtttcgat attatcaagg cttatgacga gattacaggt gttggacatc
    21961 gtgttgttgc tggtggagaa tatttcaaag aatcaacagt tgttgaggga gatgttttag
    22021 aaaaagttga agagttgagt ttgttggctc ctctacacaa cccggccaat gcagcaggtg
    22081 ttcgtgcctt caaggaattg ttgccagaca ttaccagtgt agttgttttt gatacttcct
    22141 tccacacaag tataccagag aaagcttatc gctaccctct accaacaaaa tattacacag
    22201 aaaacaaggt tcgtaaatac ggtgctcatg gtacaagtca ccagtttgta gcaggagaag
    22261 ctgcaaaact cttgggacgt ccattagaag acttgaagtt aattacctgt catattggta
    22321 acggaggctc aattacagct gtgaaagccg gcaaatctgt agacacttct atggggttca
    22381 ctcctcttgg tggtattatg atgggaacgc gtacagggga tattgatcca gctatcattc
    22441 cttatttaat gcaatataca gaggatttta acacaccaga agatatcagt cgtgttctta
    22501 accgtgaatc aggtcttttg ggagtttctg ctaattctag cgatatgcgc gatatagaag
    22561 cagctgtagc agaagggaat cacgaggcta gcttggctta tgaaatgtat gttgaccgta
    22621 tccaaaaaca tatcggtcag taccttgcag tgctaaatgg agcagatgcc attgttttca
    22681 cagcaggtgt cggtgaaaat gcagagagtt tccgtcgtga tgtaatctca gggatttcgt
    22741 ggtttggttg tgatgttgat gatgaaaaga atgtctttgg cgttacagga gacatctcaa
    22801 cagaggcagc taaaatccgt gtcttggtta ttccaacaga tgaagaatta gtcattgccc
    22861 gtgacgttga acgcttgaaa aaataagtga aactaaaaaa tattcaatac aaggagttgg
    22921 gaaagttatt tttccagctt ctttttctga tgaaattgtc caaaaccttg ctatgattgg
    22981 cttttttgaa aaatatggta taatagtagt aatttaatag atggagttta gttttgaaga
    23041 aaaactttcg tgtaaaaaga gagaaagatt ttaaggcgat tttcaaggag gggacaagtt
    23101 ttgctaatcg caaatttgtg gtctaccaat tagaaaacca gaaaaaccat tttcgagtag
    23161 gtctatcagt tagcaaaaaa ctggggaatg ccgtcactag aaatcaaatt aagcgacgga
    23221 ttcggcatat tatccagaat gcaaaaggga gtctggtaga agatgtcgac tttgttgtca
    23281 ttgctcgaaa aggagtcgaa accttgggat acgcagagat ggagaaaaat ctactccatg
    23341 tattaaaatt atcaaagatt taccgggaag gaaatgggag tgaaaaagaa actaaagttg
    23401 actagtttgc taggactgtc tctgttaatc atgacagcct gtgcgactaa tggggtaact
    23461 agcgatatta cagccgaatc ggctgatttt tggagtaaat tggtttactt ctttgcgaaa
    23521 atcattcgct ttttatcgtt tgatattagt atcggagtgg ggattattct ctttacggtc
    23581 ttgattcgta cagtcctctt gccagtcttt caggtgcaaa tggtggcttc taggaaaatg
    23641 caggaagctc agccacgcat taaggcgctt cgagaacaat atccaggtcg agatatggaa
    23701 agcagaacca aactagagca ggaaatgcgt aaagtattta aagaaatggg tgtcagacag
    23761 tcagattctc tttggccgat tttgattcag atgccggtta ttttggcctt gttccaagcc
    23821 ctatcaagag ttgacttttt aaagacaggt catttcttat ggattaacct tggtagtgtg
    23881 gatacaaccc ttgttcttcc gattttagca gcagtattca cctttttaag tacttggttg
    23941 tccaacaaag ctttgtctga gcgaaatggc gctacgactg cgatgatgta tgggattcca
    24001 gtcttgattt ttatctttgc agtttatgcg ccaggtggag tcgccctata ctggacagtg
    24061 tctaatgctt atcaagtctt gcaaacctat ttcttgaata atccattcaa gattatcgca
    24121 gagcgcgagg ccgtagtaca ggcacaaaaa gatttggaaa atagaaaaag aaaagccaag
    24181 aaaaaggctc agaaaacgaa ataaataagg aggaatctgg taatggtagt atttacaggt
    24241 tcaactgttg aagaagcaat ccagaaagga ttgaaagaat tagatattcc aagaatgaag
    24301 gctcatatca aagtcatttc tagggagaaa aaaggctttc ttggtctatt tggtaaaaaa
    24361 ccagcccaag tggatattga agcgattagt gaaacgactg ttgtcaaagc aaatcaacag
    24421 gtagtaaaag gcgttccgaa aaaaatcaat gatttgaacg agcctgtgaa gacggttagt
    24481 gaagaaaccg ttgaccttgg tcatgtggtt gatgctatta aaaaaataga ggaagaaggt
    24541 caaggtattt ctgatgaagt caaggctgaa atcttaaaac atgaaagaca tgccagcact
    24601 atcttagaag aaactggtca cattgagatt ttaaatgaac ttcaaatcga ggaagcgatg
    24661 agggaagaag caggcgctga tgaccttgaa actgagcaag atcaaactga aaatcaagac
    24721 ttgaaagaga tgggcttgaa ggtcgagcaa agttatgata ttgcccaggt ggctacggat
    24781 gtgactgctt atgttcaaac gattattgat gacatggatg ttgaggctac actttcaaat
    24841 gattataacc gtcgtagcat caatttgcaa attgatacta acgaaccagg tcgtattatc
    24901 ggctaccatg gtaaagtctt gaaggccttg caactgttgg ctcaaaatta tctttacaac
    24961 tgctattcaa gaaccttcta tatcactatt aatgtcaatg attatgttga acaccgtgca
    25021 gaagtcttgc agacctatgc gcaaaaattg gcgattcgtg ttttagaaga agggcgcagt
    25081 catcaaacag atccaatgtc gaatagtgaa cgcaagatta tccaccgtat tatttcacgt
    25141 atggatggcg tgaccagtta ctctgaaggt gatgagccaa atcgctatgt cgttgtagat
    25201 acagaataag taaaatcagg gttgacctga ttttttgcta gctagaggag gttaaactga
    25261 tgttgaataa gataagagac tatctagact tttctggttt gcagtaccgt agtcctgata
    25321 aagcgggagc agagcgagag aagatgctgg cgttccgcca caaaggacaa gaggcccgaa
    25381 aggcttttac agaactggcc aaagcctttc aagcaagcca tccagaatgg caactccaac
    25441 agactagtca gtggatgaat caggcccagc gtttgagacc acatttttgg gtttatctac
    25501 agagagacgg acaagtgaca gaacctatga tggccttacg tttgtatggg acatctactg
    25561 actttggaat ttctttggaa gtcagtttca tcgaacgtaa gaaggatgag caaacactgg
    25621 gcaagcagac caaagtttta gacattccaa ccgttaaagg gatttattat ctaacctact
    25681 ctaatggtca aagtcaacgg tgggaggcga atgaagaaaa gcgtcgtact ttacgcgaga
    25741 aggtgagaag tcaagaagtt cgaaaagttt tagtgaaggt agatgttcct atgacagaaa
    25801 attcgtctga agaagaaatc gtagaaggct tattgaagtc ttattctaaa attcttccct
    25861 attatctagc tacgagaaaa taagataatt tgtaaaacat cataaatcat acagtccaag
    25921 agtgaacagt ccgctgtgta attcttggtc tttttgtttg cgctttcgca ttatataata
    25981 aacttacaaa aacaattcaa aaggagaaca attatggaag tcgtttcaag tgttctaaat
    26041 tggttttcta gcaatatttt gcagaatccc gcatttttcg taggtttatt ggtgttgata
    26101 ggatatgcac ttttgaaaaa acctgcccat gacgtttttt cagggtttgt taaagcaaca
    26161 gtagggtata tgttgcttaa cgtgggtgct ggtggtttgg ttacaacctt tcgtccaatc
    26221 ttagcagctc ttaactacaa attccaaatt ggtgcagcgg ttatcgaccc ttactttgga
    26281 cttgctgcag caaacaacaa aattgcagca gagtttccag attttgttgg aactgcaact
    26341 acagctctat tgattggttt tggaataaat atcttgctcg tagctcttcg aaagattacg
    26401 aaggtaagaa ccctctttat tactggtcac atcatggtac aacaagctgc aacagtatct
    26461 cttatggttc tattcttagt accacaattg cgcaatgctt acggtacagc agcgattggt
    26521 atcatctgtg gactttactg ggcagttagt tcaaatatga ctgttgaggc aactcaacgc
    26581 ttgactggtg gtggcggatt tgcgattggt caccaacagc aatttgcaat ctggtttgta
    26641 gataaagtag caggacgctt tggtaagaaa gaagaaagtt tagacaatct taaattacct
    26701 aagttcctct caatcttcca cgatacagtt gttgcatctg ctaccttgat gctcgtattc
    26761 ttcggagcca ttcttttaat cttgggtcca gacattatgt ctaataaaga agtcatcact
    26821 tcaggaactc tattcaatcc tgctaaacaa gatttcttta tgtacattat ccaaacagcc
    26881 tttaccttct cagtttactt gttcgttttg atgcaaggtg tccgaatgtt cgtatctgag
    26941 ttgacaaacg ccttccaagg tatttcaaac aaattgttgc caggttcatt cccagcggtt
    27001 gacgttgcag cttcttatgg atttggttct ccaaatgctg tcctgtcagg atttatcttt
    27061 ggtttgattg gtcaattgat tacaattgtt ttgctcatcg tctttaaaaa tccgattctt
    27121 attattacag gatttgtacc agtgttcttt gacaatgcag ccattgcggt ctacgctgat
    27181 aaacgcggcg gatggaaagc ggctgttatc ctttccttta tatcaggtgt ccttcaagtt
    27241 gctctaggag ctctttgtgt ggcccttctc gatttggcat cttatggtgg ctaccatgga
    27301 aatatcgact ttgaattccc atggcttgga tttggatata tcttcaaata ccttggtatt
    27361 gttggttatg tacttgtgtg tctcttcttg cttgttattc ctcaacttca atttgccaaa
    27421 gcaaaagata aagagaaata ttacaacggt gaagttcaag aagaagctta gtatctagaa
    27481 aaggagaaat aaaatggtta aagtattagc agcgtgcgga aatggaatgg gttcatcaat
    27541 ggttatcaag atgaaggttg aaaatgctct ccgtaagctt aatcaaacag attttacagt
    27601 caattcatgc agtgtcggtg aagctaaagg tttagcagta ggatatgaca tcgtaatcgc
    27661 ttctcttcat ttgattcaag aattggaagg gcgaactaat gggaagttaa ttgggcttga
    27721 taacttgatg gatgataaag aaatcaccga aaaactcagt caagcactac agtaaaaggt
    27781 tggagggggc tggacagaaa ctgagagtta tcgtttctgt ccttctccct ctttaaataa
    27841 aggaggcaga tatgaattta aaacaagctt taattgacaa cgactcgatc cgactaggtt
    27901 tagaggctaa cgattggaaa gaagcagtca aggtagcagt agatcccttg attgaaagtg
    27961 gggcaatttt gccagagtat tacgatgcta tcattgaatc gactgaagag tatgggcctt
    28021 actatatctt gatgccaggt atggctatgc cccacgctag acctgaagct ggtgtgcaaa
    28081 gtgatgcctt ttcattaatt accttacaaa atcctgttgt attttcagat gggaaagagg
    28141 tatctgtttt gttggcacta gcagcaacaa gttcaaaaat tcacacaagt gtagccattc
    28201 cacaaattat tgccctgttt gaattagaag attctattgc acgtttacag gcttgccaga
    28261 ctaaagaaga tgtcttggct atgattgaag aatctaagga tagcccttat ctcgaaggat
    28321 tggatttgga aagttagaaa gaggaataaa gaaatgacaa aaagaatacc taatttacaa
    28381 gttgcattag accattcaga cttgcaagga gcgattaaag cagctgtttc tgttggtcag
    28441 gaagtagata ttatcgaagc tggaactgtt tgcttgcttc aagttggaag tgaactggct
    28501 gaagtcttgc gtagcctttt cccagataag attattgtgg cagacacaaa atgtgctgat
    28561 gctggtggaa cagttgctaa aaataatgcg gttcgtggag cagactggat gacttgtatc
    28621 tgttgtgcaa ccatccctac tatggaagca gctctaaagg ctatcaagac tgaacgagga
    28681 gaacgaggcg aaatccagat cgagctttat ggcgattgga cttttgaaca agctcagctt
    28741 tggctagatg caggtatctc acaagctatt tatcaccaat ctcgtgatgc tcttcttgct
    28801 ggtgaaactt ggggtgaaaa agaccttaat aaggttaaaa aactcattga catgggcttc
    28861 cgtgtatctg taacaggtgg tctagatgta gatactctca aactctttga aggtgttgat
    28921 gtctttacct ttatcgcagg tcgtggaatt acagaggctg tggatccagc aggagcagcg
    28981 cgtgccttca aggatgaaat caaacgaatt tgggggtaaa tcatggtacg tccaattgga
    29041 atttatgaaa aggcaacccc aacacacttt acttggctag aacgtttaaa ttttgccaag
    29101 gagttaggct ttgattttat cgagatgtct attgacgaac gtgacgagcg tttagcaaga
    29161 cttgactgga gtaaggaaga acgcttggaa gttgtcaaag aaatctatga aactggtgtt
    29221 cgtattcctt ctatctgttt ttcaggccat cgtcgctacc cattgggatc aaaagattca
    29281 gttctagagg aaaaatctct agaactcatg aaaaaatgta tcgaattagc tcaagacttg
    29341 ggagttcgta cgattcaatt agctggttac gatgtttact atgaggaaaa gtcaccccag
    29401 acacgccaac gttttatcaa aaatttgaga aaagcctgtg actgggctga agaagctcag
    29461 gtggtacttg ctattgaaat tatggatgat cctttcatca gtagcatcga aaaatatttg
    29521 gctatagaaa aagagattga ctctcccttc ctctttgtat atccagatat tggtaatgtg
    29581 tctgcatggc ataatgatat ctatagtgag ttttatcttg gtcatcatgc catcgcagct
    29641 ctccatctca aggatactta tgcagtgaca gaaaattcaa agggccagtt ccgagatgta
    29701 cctttcgggc aaggttgtgt caaatgggaa gaagctttcg atattttaaa ggaaaccaat
    29761 tataatggac ctttcctaat cgaaatgtgg tctgaaaatt gtgaaacagt agaagaaaca
    29821 cgcgcagcca ttcaagaggc gcaagctttt ctctatccac tcattaagaa agcaggtttg
    29881 atgtaagatg aatcaagtaa tcaatgctat gcgtaaacga gtttgtgatg ccaatcaatc
    29941 attgccaaaa catggacttg tcaaatttac ctgggggaat gtatctgaag tcaatcgcga
    30001 actcggtgtc attgttatca aaccatcagg cgtggattat gacgaattga cacctgaaaa
    30061 catggtagtg actgatctag atggtaagat cctagaaggg gatttaagac catcttccga
    30121 cctcccaact catgtgcaat tatataaggc ttggtcagaa attggtagtg tggttcacac
    30181 ccattcgaca gaagctgttg gttgggctca ggcaggtcgt gatattcctt tctacggaac
    30241 aacccatgca gattatttct acggttcaat cccttgcgcc cgtagtttga ccaaggacga
    30301 agtagaagtg acctatgaaa aagatactgg cctggttatc gtagaagaat ttgaacatcg
    30361 cggacttaac ccggttgaag taccaggaat tgttgtacgc aatcacggtc cattcacctg
    30421 gggcaaaaat ccagagaatg ctgtttatca ctctgtcgta ctagaggaag tatcaaagat
    30481 gaatcgcttt acagaacaaa tcaatccaag agttggacct gctccccagt acatactaga
    30541 aaaacactac caacgtaaac atggaccaaa tgcttattat ggtcaaaagt aagaacgatg
    30601 aaggaggaga aaaagataaa tttagctcct ctttttacat ttgattttta ttgagagtaa
    30661 agttggagtt gaagtaattt taaaagattt tttagaaata gcgcttgata tatatatggt
    30721 aaaataaaaa gaattgctgt gatatcaata gatttggggg attttttaat atggtactgg
    30781 ataaggcaag ttgtgatttg cttcaatatt tgatggatca agaaacgtcc aaaacgatta
    30841 tggcgatttc gaaagatttg aaagagtcaa gaaggaaaat ttattatcac attgacaaaa
    30901 tcaatgctgc tctgggtgac gaggcgcttc acatcattag tattccacga attggtattc
    30961 acttaacgga agagcagaga gatgcttgtt gtaaactatt atcggaagta gattcgtacg
    31021 attatatcat gagtgcgcat gaacgtatga tgataatgtt actatggata ggtatttcta
    31081 aagaacgtat tacgattgaa aaattgatag agttaacaga ggtatctagg aatactgttc
    31141 tcaatgattt gaatagcatt cgttatcaac taactttgga acaatatcag gtgaccttgc
    31201 aagtgagcaa gtcacaggga taccaccttc atgcccaccc tcttaataaa attcagtatc
    31261 ttcaatcgct tctatatcat atttttatgg aagaaaatgc cacttttgta tctattttag
    31321 aagataagat gaaagagagg ttagatgatg agtgtttgct ttctgttgaa atgaaccaat
    31381 tttttaagga acaggttcct ttagttgaac aagatttagg gaagaaaata aaccatcatg
    31441 aaataacttt tatgttgcag tttctacctt atttgctgtt aagctgtcat aatgttgaac
    31501 agtatcaaga aagacatcag gatatagaga aagaattttc tttgataaga aaaagaatag
    31561 agtatcaggt gtctaagaaa ttaggagaac ggttgtttca aaagtttgaa atttctttgt
    31621 caggacttga agtttctctt gtagctgttc tcctcctctc ctatcgtaaa gatttggata
    31681 ttcatgcaga aagtgatgat tttcggcaat taaaacttgc tttagaagaa tttatctggt
    31741 attttgaatc acaaatccga atggagattg agaacaagga tgatttgtta cgaaatttga
    31801 tgatccactg taaatccttg ttatttagaa agacttacgg tattttttct aaaaatcctc
    31861 taacaaaaca aattcgatcc aagtatggag aattattttt agtcactaga aaatctgcgg
    31921 aaattttaga aggagcatgg tttattcggc taacagacga tgatattgcc tatttgacga
    31981 ttcatattgg aggattttta aagtatacac catcgtctca aaaaaatatg aaaaaagttt
    32041 atctcgtttg tgatgaaggt gttgcggttt cgagactttt gctgaaacaa tgcaaacttt
    32101 attttccaaa tgagcaaatt gacactgtat ttacaacaga acaatttaag agtgtggaag
    32161 atattgcaca agttgatgta gtgattacta ctaatgatga tttggatagc agatttccga
    32221 ttttaagggt taatcctatc cttgaagcag aagatatttt gaaaatgcta gactatctta
    32281 aacacaatat atttcgtaat gagagcaaaa gtttcagtga aaatctttct agtcttattt
    32341 cgtcttatat tgtagacagc aagttggcta gtaagttcca agaagaggtt caaacactta
    32401 taaatcaaga aatagtagtt caagcttttt tggaagatat ttgaaggaca gtccaatgat
    32461 gaacacaaac ctgtgttttt cttggtcttt tttagtgttt tgaagggtgg tatactaatc
    32521 tcaaagataa caattatatc caaaggaggc aacatatgcc aaacgtcaaa gaaattacaa
    32581 gagagtcatg gattttagcc actttcccag agtggggaac atggttgaac gaagaaatcg
    32641 aagaagaagt cgtacctgaa ggcaattttg ccatgtggtg gctaggcaac tgtggtactt
    32701 ggattaagac accagctggt gctaacgttg tcatggacct ttggtcaaac cgtggaaaat
    32761 caaccaaaaa agtgaaagat atggttcgtg ggcaccaaat ggcaaatatg gcaggtgttc
    32821 gtaagttgca accaaacttg cgtgttcagc caatggttat cgatccattt gctatcaacg
    32881 aactagacta ttacttagtt tcacacttcc acagtgatca tatcgaccca tacacagctg
    32941 cagcaattct caacaatcct aagttagagc atgttaagtt tatcggtcct taccactgtg
    33001 gacgaatctg ggaaggatgg ggtgttccaa aagaacgtat catcgttgtt aaaccaggtg
    33061 acactatcga attaaaagat atgaagattc atgcagtaga atcatttgac cgtacttgct
    33121 tggtaactct cccagtgaac ggtgctgatg agacaggcgg tgaacttgct ggattggctg
    33181 ttacagatga agaaatggct caaaaggctg ttaactatat ctttgaaaca ccaggtggaa
    33241 ccatctatca tggtgcagat tctcacttct caaactattt tgcaaaacat ggtaaagact
    33301 ttaaaattga tgttgctttg aataactatg gtgaaaatcc ggtaggtatc caagacaaaa
    33361 tgacatctat cgaccttctt cgtatggcag aaaatctgcg taccaaagtt attatcccag
    33421 ttcactatga tatctggtct aacttcatgg cttctactaa tgagattcta gaactttgga
    33481 aaatgcgaaa agatcgcttg caatacgatt tccatccatt tatctgggaa gttggcggta
    33541 agtacactta tcctcaagat caacacttag tagaatacca tcatccacgt ggttttgatg
    33601 attgttttga acaagactct aacattcaat ttaaagcttt gctataatat aaaaatattc
    33661 tttggaggtt atccgtatgt tgcatgatac ggataatttt catataatag taaaatagaa
    33721 tgtgtgattc aataatcacc tcaaatagaa aggaaattct atgtcaaatc tatctgttaa
    33781 tgcaattcgt tttctaggta ttgacgccat taataaagcc aactcaggtc atccaggtgt
    33841 ggttatggga gcggctccga tggcttacag cctctttaca aaacaacttc atatcaatcc
    33901 agctcaacca aactggatta accgcgaccg ctttattctt tcagcaggtc atggttcaat
    33961 gctcctttat gctcttcttc acctttctgg ttttgaagat gtcagcatgg atgagattaa
    34021 gagtttccgt caatggggtt caaaaacacc aggtcaccca gaatttggtc atacggcagg
    34081 gattgatgct acgacaggtc ctctagggca agggatttca actgctactg gttttgccca
    34141 agcagaacgt ttcttggcag ccaaatataa ccgtgaaggc tacaatatct ttgaccacta
    34201 tacttacgtt atctgtggag acggagactt gatggaaggt gtctcaagcg aggcagcttc
    34261 atacgcaggt ttgcaaaaac ttgataagtt ggttgttctt tatgattcaa atgatatcaa
    34321 cttggatggt gagacaaagg attcctttac agaaagtgtt cgtgaccgtt acaatgccta
    34381 cggttggcat actgccttgg ttgaaaatgg aacagacttg gaagccatcc atgctgctat
    34441 cgaaacagca aaagcttcag gcaagccatc tttgattgaa gtgaagacgg ttattggata
    34501 cggttctcca aacaaacaag gaactaatgc tgtacacggc gcccctcttg gagcagatga
    34561 aactgcatca actcgtcaag ccctcggttg ggactacgaa ccatttgaaa ttccagaaca
    34621 agtatatgct gatttcaaag aacatgttgc agaccgtggc gcatcagctt atcaagcttg
    34681 gactaaatta gttgcagatt ataaagaagc tcatccagaa ctggctgcag aagtagaagc
    34741 catcatcgac ggacgtgatc cagtcgaagt gactccagca gacttcccag ctttagaaaa
    34801 tggtttttct caagcaactc gtaattcaag tcaagatgcc ttgaatgttg tggcagctaa
    34861 attaccaacc tttctaggtg gatcagctga ccttgctcac tcaaacatga cttatatcaa
    34921 gacggatgga cttcaagacg atgccaatcg cttgaatcgt aacattcagt ttggtgttcg
    34981 tgaatttgca atgggaacaa tcttgaacgg gatggccctt catggtggac ttcgtgtata
    35041 cggtggaact ttcttcgtct tctctgacta tgtgaaggca gctgtccgct tgtcagcctt
    35101 acaaggactt cctgtgactt atgtctttac ccatgattca atcgcagttg gggaagatgg
    35161 tccgactcac gaaccagttg agcatttagc aggtcttcgt gctatgccaa atctaaatgt
    35221 tttccgtcca gcagatgcgc gtgaaacgca agcagcttgg taccttgcag tgacaagtga
    35281 gaaaacacca actgcccttg tcttgacacg tcaaaacttg actgttgaag atggaacaga
    35341 cttcgacaag gttgctaaag gtgcttatgt tgtatatgaa aatgcagccg actttgatac
    35401 catcttgatt gcgacaggtt cagaggttaa tcttgctgtc tcagctgcta aagaattggc
    35461 tagtcaaggc gaaaaaatcc gcgtagtcag catgccatct acagatgtct ttgataaaca
    35521 agatgcagct tacaaggaag agattcttcc aaatgcagtc cgccgtcgtg ttgcagtcga
    35581 aatgggtgca agtcaaaact ggtacaaata tgttggtctc gatggtgccg ttctaggtat
    35641 tgataccttc ggagcctctg ccccagcacc aaaagtattg gcagaatatg gctttactgt
    35701 agaaaatctt gtaaaaattg ttcgaaactt gaaataatcc taaaaatcag ggcgtaagct
    35761 ctggtttttc ttaccagaaa agtaaggtac aatcttgtaa aagtagctga aatttgatat
    35821 agtagtccta tgtaaaagac aaaggagaaa acaatgaatc caaatattac ttttttaatc
    35881 atgcttgtag gtatgatggc cttgatgttc tttatgcaac gttctcaaaa gaaacaagct
    35941 caaaagcgta tggaaagctt aaataaacta caaaaaggct atgaagtgat tacaatcggt
    36001 ggactttatg gaacagtcga tgaagtagat acggagaagg gaacaatagt tcttgacgta
    36061 gatggagttt acttgacttt tgaactagct gctatcaaga cagtattacc gctgaaagaa
    36121 acagcttcac tagaaggcgc aattgaaaaa taagacggga tcacgaactc ccgtttttct
    36181 ataaaagaaa ggaaatggga tgaaaaaatt agtctttgtc tgtctgggaa atatttgccg
    36241 tagccctatg gccgagtttg ttatgaaatc aatgacagat aactacgaaa tccaaagtcg
    36301 agcaacttcc tcttgggaac atggcaatcc gattcataag gggactcagg gaatttttca
    36361 agagtatgag attccttatg acaagaacaa gacatcgctt cagattagta aggaagattt
    36421 tgaagccttt gattatatta tcggaatgga cgcttcaaat atttctgact tatgtcagat
    36481 gtgtccagta gactgtcaag ataagattta ctcattttca tctgaaagtg ttccagaccc
    36541 ttggtataca ggagattttg aagaaaccta tcgacgtgtt caagagggct gtcaagcttg
    36601 gttagaacgt ttagaaaagg agagttaagg tggaaaatct tacgaatttt tacgaaaagt
    36661 atcgtgtcta tctgactcgt ccacgtttag agcttttggc agtagttacc attgttttct
    36721 gtgctgtact cgtctttttt ctaaatattc caggaaaagg tgtcttaaaa ctcgataatg
    36781 gaacgattgt ttatgatggc agtcttgtcc gtggtaaaat gaatggccaa ggtaccatta
    36841 ccttccaaaa tggagaccaa tatacaggtg gcttcaacaa tggagccttc aacggaaaag
    36901 gtacctttca atctaaagaa ggctggacct acgaaggtga ttttgtaaat ggtcaggctg
    36961 aaggaaaagg gaaactaaca acagaacaag aagtcgttta tgaaggaact tttaaacaag
    37021 gcgtttttca acaaaaataa agcctcctta tcaaaggagg tattattaga atcacaaggt
    37081 aagcgcttac ctgtaaatcc ctttctttcc aaatccctct tccaagcaag tttgtgaaat
    37141 aaaaaatatt tgaaataaat ttcacaaact tcaaagataa aacttgataa gaaaagaaaa
    37201 tgagaaaagt ttcacaagag tttaaaaatt ctttgtgaaa tgtttatgaa actgtttaca
    37261 aagttgaaat aatgcgttat aataaacttg tgaaaaaatt aacaaaggat atcgttcctt
    37321 gaaagctatg gaggaaaata tggctgataa aaaaactgtg acaccagagg aaaagaaact
    37381 cgttgctgaa aaacacgtag atgagttggt tcaaaaagct ctagttgccc ttgaagaaat
    37441 gcgtaaattg gatcaagaac aagttgacta catcgttgcc aaagcatcag tagcagcttt
    37501 ggatgcccac ggagaattgg ctttacatgc ctttgaagaa acaggacgtg gtgtatttga
    37561 agataaagca actaagaact tgtttgcttg tgaacacgtg gtaaacaaca tgcgtcacac
    37621 taagacagtt ggcgttatcg aagaagatga tgtaacagga ttgaccctga ttgctgaacc
    37681 agttggtgtt gtttgtggta tcactccaac aacaaaccca acatcaacag cgatcttcaa
    37741 atcattgatt tcattgaaga cacgtaatcc aatcgtcttt gccttccatc catcagctca
    37801 agaatcatca gctcatgcag ctcgtatcgt ccgcgatgca gctatcgcag ctggtgctcc
    37861 tgaaaactgt gtacagtgga tcactcaacc atctatggaa gcaactagtg cccttatgaa
    37921 ccacgaaggt attgcaacaa tccttgcaac aggtggtaat gccatggtta aagccgcata
    37981 ctcatgtggt aaaccagctc ttggggtagg tgccggaaac gttccagctt atgttgaaaa
    38041 atcagcaaac attcgtcaag cagcacacga tatcgtcatg tctaaatcat ttgataacgg
    38101 tatggtctgt gcatctgaac aagcagttat cattgataaa gaaatttacg atgaatttgt
    38161 agcagagttc aaatcttacc acacttactt tgtaaacaaa aaagaaaaag ctcttcttga
    38221 agagttctgc ttcggcgtca aagcaaacag caaaaactgt gctggtgcaa aattgaacgc
    38281 tgacatcgtt ggtaaaccag caacttggat tgcagaacaa gcaggattta cagttccaga
    38341 aggaacaaac attcttgctg cagaatgtaa agaagttggc gaaaatgagc cattgactcg
    38401 tgaaaaattg tcaccagtta ttgcagtttt gaaatctgaa agccgtgaag atggtattac
    38461 taaggctcgt caaatggttg aatttaacgg tcttggacac tcagcagcta tccacacagc
    38521 tgacgaagaa ttgactaaag aatttggtaa agctgttaaa gctattcgtg ttatctgtaa
    38581 ctcaccttct acttttggtg gtatcgggga cgtttacaat gccttcttgc catcattgac
    38641 acttggatgt ggttcttacg gacgcaactc agttggggat aacgttagtg ccattaacct
    38701 cttgaatatc aaaaaagtcg gaagacggag aaataacatg caatggatga aacttccttc
    38761 aaaaacatac tttgaacgtg attcaattca ataccttcaa aaatgtcgtg acgttgaacg
    38821 tgtcatgatc gttactgacc atgccatggt agagcttggt ttccttgatc gtatcatcga
    38881 acaactggac cttcgtcgca ataaggttgt ttaccaaatc tttgcggatg tagaaccgga
    38941 tccagatatc acaactgtaa accgtggtac tgagattatg cgtgccttca aaccagatac
    39001 catcatcgca ctcggtggtg ggtctccaat ggatgctgcc aaagtaatgt ggctcttcta
    39061 cgagcaacca gaagtggact tccgtgacct tgtccaaaaa ttcatggata tccgtaaacg
    39121 tgccttcaag ttcccattgc ttggtaagaa gactaaattc atcgcgattc caactacatc
    39181 tggtacagga tctgaagtaa caccatttgc cgttatctct gataaagcaa acaaccgtaa
    39241 atacccaatc gctgactact cattgacacc aactgtggca atcgtagatc ctgctttggt
    39301 attgacagtt ccaggatttg ttgctgctga tactggtatg gacgtattga ctcacgcgac
    39361 agaagcatac gtatcacaaa tggctagtga ctacactgat ggtttagcac ttcaagccat
    39421 taaattggtc tttgaaaatc tcgaaagctc agttaagaat gcagacttcc actcacgtga
    39481 gaaaatgcat aacgcttcaa caatcgctgg tatggccttt gccaatgcct tcctaggtat
    39541 ttctcactca atggcccata agattggtgc gcaattccac acaatccacg gtcgtacaaa
    39601 tgctatcttg cttccatacg ttatccgtta caacggtaca cgtccagcta agacagcaac
    39661 atggcctaag tacaactact accgtgcaga tgaaaaatac caagatatcg cacgcatgct
    39721 tggacttcca gcttctactc cagaagaagg ggttgaatct tacgcaaaag ctgtctacga
    39781 actcggtgaa cgtattggga tccaaatgaa ttttagagac caaggaattg acgaaaaaga
    39841 atggaaagaa cattctcgtg aattagcctt cctggcttat gaagaccaat gttcaccagc
    39901 taacccacgt cttccaatgg tagaccatat gcaagaaatc atcgaagatg catactatgg
    39961 ctacaaagaa agaccaggac gccgtaaata attgtttatc agtctagaag caagacaaaa
    40021 actcaatttg agggaaagat ccagtaattt ttctatgata aaaggcatcc tatcaaggtt
    40081 tttgaacacc tgataggatg cctttttatg atattgaggc ctttttgccc tttttgaaaa
    40141 actagaatag aaacaaaata tataatagat tgaaactgga atagtacact tctgcttcta
    40201 aaacattgtt agaattcgat ttgactgtcc tgatcgattt gtcctattcc tatttcattt
    40261 ta
//
LOCUS       DAVLGK010000014        39901 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLGK010000014 DAVLGK010000000
VERSION     DAVLGK010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39901
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.014"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            593..2746
                     /locus_tag="VXE01_000840"
     CDS             593..2746
                     /locus_tag="VXE01_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0749785.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKM
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2759..4108
                     /locus_tag="VXE01_000841"
     CDS             2759..4108
                     /locus_tag="VXE01_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV0749786.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTVKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAEINLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4278..4985
                     /locus_tag="VXE01_000842"
     CDS             4278..4985
                     /locus_tag="VXE01_000842"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0749787.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFTEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5187..8912
                     /locus_tag="VXE01_000843"
     CDS             5187..8912
                     /locus_tag="VXE01_000843"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV0749788.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNISE
                     ANILFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTVEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9005..10447
                     /locus_tag="VXE01_000844"
     CDS             9005..10447
                     /locus_tag="VXE01_000844"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV0749789.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10484..11506
                     /locus_tag="VXE01_000845"
     CDS             10484..11506
                     /locus_tag="VXE01_000845"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV0749790.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11503..12048
                     /gene="purN"
                     /locus_tag="VXE01_000846"
     CDS             11503..12048
                     /gene="purN"
                     /locus_tag="VXE01_000846"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV0749791.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYIKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12132..12641
                     /locus_tag="VXE01_000847"
     CDS             12132..12641
                     /locus_tag="VXE01_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0749792.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12666..14213
                     /gene="purH"
                     /locus_tag="VXE01_000848"
     CDS             12666..14213
                     /gene="purH"
                     /locus_tag="VXE01_000848"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV0749793.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14335..15597
                     /gene="purD"
                     /locus_tag="VXE01_000849"
     CDS             14335..15597
                     /gene="purD"
                     /locus_tag="VXE01_000849"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV0749794.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            16000..16488
                     /gene="purE"
                     /locus_tag="VXE01_000850"
     CDS             16000..16488
                     /gene="purE"
                     /locus_tag="VXE01_000850"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV0749795.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRAISGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16475..17566
                     /gene="purK"
                     /locus_tag="VXE01_000851"
     CDS             16475..17566
                     /gene="purK"
                     /locus_tag="VXE01_000851"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV0749796.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17576..17803
                     /locus_tag="VXE01_000852"
     CDS             17576..17803
                     /locus_tag="VXE01_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV0749797.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            17866..19164
                     /gene="purB"
                     /locus_tag="VXE01_000853"
     CDS             17866..19164
                     /gene="purB"
                     /locus_tag="VXE01_000853"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV0749798.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19219..23157)
                     /gene="strH"
                     /locus_tag="VXE01_000854"
     CDS             complement(19219..23157)
                     /gene="strH"
                     /locus_tag="VXE01_000854"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0749799.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQTLNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(23472..24188)
                     /locus_tag="VXE01_000855"
     CDS             complement(23472..24188)
                     /locus_tag="VXE01_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0749800.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24536..26323
                     /locus_tag="VXE01_000856"
     CDS             24536..26323
                     /locus_tag="VXE01_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV0749801.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPTYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26320..26796
                     /locus_tag="VXE01_000857"
     CDS             26320..26796
                     /locus_tag="VXE01_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0749802.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            26824..27729
                     /locus_tag="VXE01_000858"
     CDS             26824..27729
                     /locus_tag="VXE01_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0749803.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            27716..28531
                     /locus_tag="VXE01_000859"
     CDS             27716..28531
                     /locus_tag="VXE01_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0749804.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28538..28942
                     /locus_tag="VXE01_000860"
     CDS             28538..28942
                     /locus_tag="VXE01_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0749805.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29195..30361
                     /locus_tag="VXE01_000861"
     CDS             29195..30361
                     /locus_tag="VXE01_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0749806.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESLATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30477..31514
                     /locus_tag="VXE01_000862"
     CDS             30477..31514
                     /locus_tag="VXE01_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV0749807.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31722..32576
                     /locus_tag="VXE01_000863"
     CDS             31722..32576
                     /locus_tag="VXE01_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0749808.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKRLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            32713..32970
                     /locus_tag="VXE01_000864"
     CDS             32713..32970
                     /locus_tag="VXE01_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV0749809.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33012..33374)
                     /locus_tag="VXE01_000865"
     CDS             complement(33012..33374)
                     /locus_tag="VXE01_000865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749810.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     NHIYGKVKLTWFEEIFEEYKSLHNKTHITKVLMNCTPKVRQKKSNFWGSVHSTPDTMR
                     FFNFKDFLQLLLTHIKLF"
     gene            complement(33428..33724)
                     /locus_tag="VXE01_000866"
     CDS             complement(33428..33724)
                     /locus_tag="VXE01_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0749811.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(33714..33875)
                     /locus_tag="VXE01_000867"
     CDS             complement(33714..33875)
                     /locus_tag="VXE01_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV0749812.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            33945..34709
                     /locus_tag="VXE01_000868"
     CDS             33945..34709
                     /locus_tag="VXE01_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV0749813.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(34949..35191)
                     /locus_tag="VXE01_000869"
     CDS             complement(34949..35191)
                     /locus_tag="VXE01_000869"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749814.1"
                     /translation="MRTKASLRKLVTGCSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     SKHCFEVVDRTDEVSSKHCFEVADRTDEVSNIYTAR"
     gene            35409..36788
                     /locus_tag="VXE01_000870"
     CDS             35409..36788
                     /locus_tag="VXE01_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0749815.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            36802..37467
                     /locus_tag="VXE01_000871"
     CDS             36802..37467
                     /locus_tag="VXE01_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV0749816.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            37581..37676
                     /locus_tag="VXE01_000872"
                     /pseudo
     CDS             37581..37676
                     /locus_tag="VXE01_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            37867..38406
                     /locus_tag="VXE01_000873"
     CDS             37867..38406
                     /locus_tag="VXE01_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0749817.1"
                     /translation="MKLLSIAIPSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            38473..38883
                     /locus_tag="VXE01_000874"
     CDS             38473..38883
                     /locus_tag="VXE01_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0749818.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTTEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            38999..>39901
                     /gene="pavB"
                     /locus_tag="VXE01_000875"
     CDS             38999..>39901
                     /gene="pavB"
                     /locus_tag="VXE01_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0749819.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETV"
BASE COUNT        10996 a         7766 c         9329 g        11810 t
ORIGIN      
        1 aaataatcaa aactataaat gatgaatctg aatcaaaatt attttgcgca tgtaaagagg
       61 agtcttatag taacgagtca aaaaaggagt aactatgaat cgtgatttag aacggtgtta
      121 tctattctga ctaggaatag atcataccag aggtagctta gaaatagcag ggacattaga
      181 aattgaagta ataaatagga tgtcgtaagt gttactatca atgatttatt tgtttcaagc
      241 ttgcctaggg tgacagtaaa aaatcaattt cctttcaata gcatattttt agtgggcagg
      301 actcttgttc tgcctatttt tttatccaaa aagtgcagtt gggagggaga taggctcatt
      361 tgggaaggaa gtccagtttt tgtttagtga ttgaggtaag atagttgtta tcagatgagt
      421 ttatactctt cgaaaatcaa attcaaacca cgtcaacgtc gccttgacgt atatatgtga
      481 ctgacttcgt cagtcctatc tacaacctca aaacagtgtt ttgagcagcc tgcggctagt
      541 ttcctagttt gctctttgat tttcattgag tattagggaa aaggagatga atatgaaatt
      601 tgggaaacgt cactatcgtc cgcaagtgga tcagatggac tgcggtgtag cttcattagc
      661 catggttttt ggctactatg gtagttatta ttttttggct cacttgcgag aattggctaa
      721 gatgaccatg gatgggacga cggctttggg cttggtcaag gtggcagagg agattggttt
      781 tgagacgcga gccattaagg cggatatgac gctttttgac ttgccggatt tgacttttcc
      841 ttttgttgcc catgtgctta aggaagggaa attgctccac tactatgtgg tgactgggca
      901 ggataaggat agcattcata ttgccgatcc agatcccggg gtgaagttga ctaaactgcc
      961 acgtgagcgt tttgaggaag aatggacagg agtgactctt tttatggcgc ctagtccaga
     1021 ctataagcct cataaggaac aaaaaaatgg tctgctctct tttatcccta tattagtgaa
     1081 gcagcgtggc ttgattgcca atatcgtttt ggcaacactc ttggtaaccg tgattaacat
     1141 tgtgggttct tattatctgc agtctatcat tgatacctat gtgccagatc agatgcgttc
     1201 gacactaggg attatttcta ttgggctagt catcgtctac atcctccagc aaatcttgtc
     1261 ttacgctcag gagtatctct tgcttgtttt agggcaacgc ttgtcgattg acgtgatttt
     1321 gtcctatatc aagcatgttt ttcacctccc tatgtccttc tttgcgacac gcaggacagg
     1381 ggaaattgtg tctcgtttca cggatgctaa cagtatcatc gatgcgctgg cttcgaccat
     1441 cctttcgatt ttcctagatg tgtcaacggt tgtcattatt tcccttgttc tattttcaca
     1501 aaataccaat ctctttttca tgactttatt ggcgcttcct atctacacag tgattatctt
     1561 tgcctttatg aagccgtttg aaaagatgaa tcgggatacc atggaagcca atgcggttct
     1621 gtcttcttct atcattgagg acatcaacgg tattgagact atcaagtcct tgaccagtga
     1681 aagtcagcgt taccaaaaaa ttgacaagga atttgtggat tatctgaaga aatcctttac
     1741 ctatagtcga gcagagagtc agcaaaaggc tctgaaaaag gttgcccatc tcttgcttaa
     1801 tgtcggcatt ctctggatgg gggctgttct ggtcatggat ggcaagatga gtttggggca
     1861 gttgattacc tataatacct tgctggttta ctttaccaat cctttggaaa atatcatcaa
     1921 tctgcaaacc aagcttcaga cagcgcaggt tgccaataac cgtctaaatg aagtgtatct
     1981 agtagcttct gagtttgagg agaagaaaac agttgaggat ttgagcttga tgaagggaga
     2041 tatgaccttc aagcaggttc attacaagta tggctatggt cgagacgtct tgtcggatat
     2101 caatttaacc gttccccaag ggtctaaggt ggcttttgtg gggatttcag ggtcaggtaa
     2161 gacgactttg gccaagatga tggttaattt ttatgaccca agtcaagggg agattagtct
     2221 gggtggtgtc aatctcaatc agattgataa aaaagccctg cgccagtaca tcaactatct
     2281 gcctcaacag ccctatgtct ttaacggaac gattttggag aatcttcttt tgggagccaa
     2341 ggaggggacg acacaggaag atatcttacg ggcggtcgaa ttggcagaga ttcgagagga
     2401 tatcgagcgc atgccactga attaccagac agaattgact tcggatgggg cagggatttc
     2461 aggtggtcaa cgtcagagaa tcgctttggc gcgtgctctc ttgacagatg cgccggtctt
     2521 gattttggat gaggcgacta gcagtttgga tattttgaca gagaagcgga ttgtcgataa
     2581 tctcatagct ttggacaaga ccttgatttt cattgctcac cgcttgacta ttgctgagcg
     2641 gacagagaag gtagttgtct tggatcaggg caagattgtc gaagaaggaa agcatgctga
     2701 tttgcttgca cagggtggct tttacgccca tttggtcaat agctagaaag aggagaggat
     2761 gaaaccagaa tttttagaaa gtgcggagtt ttataatcgt cgttaccata atttttccag
     2821 tagtgtgatt gtacccatgg cccttctgct cgtgttttta cttggctttg caactgttgc
     2881 agaaaaggag atgagtttgt ccactagagc tactgtcgaa cctagtcgta tccttgcaaa
     2941 tatccagtca actagcaaca atcgtattct tgtcaatcat ttggaagaaa ataagctggt
     3001 taagaagggg gatcttttgg ttcaatacca agaaggggca gagggtgtcc aagcggagtc
     3061 ctatgccagt cagttggaca tgctaaagga tcaaaaaaag caattggagt atctgcaaaa
     3121 gagcctgcaa gaaggggaga accactttcc agaggaggat aagtttggct accaagccac
     3181 ctttcgcgac tacatcagtc aagcaggcag tcttagggct agtacatcgc aacaaaatga
     3241 gaccatcgcg tcccagaatg cagcagctag ccaaacccaa gccgaaatcg gcaacctcat
     3301 cagtcaaaca gaggctaaaa ttcgcgatta ccagacagtt aagtcagcta ttgaaacagg
     3361 tgcttccttg gccggtcaga atctagccta ctctctttac cagtcctaca agtctcaggg
     3421 cgaggaaaat ccccaaacta aggttcaggc agttgcacag gttgaagcac agatttctca
     3481 gttagaatct agtcttgcta cttaccgtgt ccagtatgca ggttcaggta cccagcaagc
     3541 ctatgcgtca gggttaagca gtcaattgga atcccttaaa tcccaacact tggcaaaggt
     3601 tggtcaggaa ttgacccttc tagcccagaa aatcttggag gcagagtcag gtaagaaggt
     3661 acagggaaat cttttagaca aggggaaaat tacggcaagt gaggatgggg tgcttcatct
     3721 taatcctgag accagtgatt ctagcatggt tgcagaaggt gccctactag cccaacttta
     3781 tccatctttg gaaagagaag ggaaagccaa actcacagcc tatctaagtt caaaagatgt
     3841 agcaagaatc aaggtcggtg attctgttcg ctatactacg actcatgatg ccgggaatca
     3901 actttttcta gattctacta ttacaagtat tgatgcgaca gctactaaga ctgagaaagg
     3961 gaatttcttt aaaatcgagg cggagattaa tctaacttcg gagcaggctg aaaaacttag
     4021 gtacggggtg gaaggccgtc tacagatgat tacgggcaag aaaagttatc tacgttatta
     4081 tttggatcaa tttttgaaca aagagtaatg ttcgtgtttt tagagttaaa taatttttaa
     4141 actgtgagaa agattcttct tgcagttttt tctttacaat ttttgaaaaa catctgctat
     4201 ttattcggtt aaattcttgt gttttttggt tttttgtggt aaaatgtgct caagtaatac
     4261 gaaaggcgaa ctttaaaatg tcaaaacaat tgatctattc gggaaaagct aaagatatct
     4321 atacaactga ggatgaaaat cttattattt caacttacaa ggaccaggcg actgctttca
     4381 acggtgtcaa gaaggagcag attgcaggta agggagtctt gaataatcag atctcatctt
     4441 ttatttttga gaaattaaat gcggctggtg tggcgactca ctttgtggag aaactttcag
     4501 acacggaaca actcaataaa aaggttaaga ttattccttt ggaagtcgtg ctccgcaact
     4561 atactgctgg ttccttttca aaacgttttg gtgtggatga gggaatcgcc ttggagactc
     4621 cgattgtcga attttactac aaaaatgatg atttggatga tccatttatc aatgatgagc
     4681 atgtgaaatt cctacagatt gcgggtgacc agcagattgc ctacttgaag gaagaaacgc
     4741 gtcgtatcaa tgaactattg aaagtctggt ttactgagat tgggcttaaa ttgattgact
     4801 ttaagctaga gttcggtttt gacaaggatg gcaagattat cttggcagac gaattttcac
     4861 cagataactg ccgcttgtgg gacgctgatg gcaaccacat ggataaggat gttttccgta
     4921 gaggattggg agaactaacc gacgtttatg agattgtttg ggaaaagttg caggaattga
     4981 aataatctgt ttgcaacgga aaaccttcgt ctctcaacta aaaggactca ggctgaaaag
     5041 gtcccccaga ccttttcact ctgtagagaa ctaggtgaac taacagatgt ttacgaaatt
     5101 gtctgggaaa agttgcaggg tttaaaataa caacctcaag gctgtttggg aatattgcaa
     5161 gagctgaaat aaaggaataa gaattgatgg ataaacgtat ttttgttgaa aaaaaggctg
     5221 attttcaggt caagtcagag agtttggtta gagagctcca gcacaacttg ggactgtcaa
     5281 gcttgaaaag tattcgtatt gtgcaagtat atgatgtatt tgacttggct gaggacttgt
     5341 ttgcacctgc agagaagcac attttctctg agcagggaac cgaccatgtt ttagatgaag
     5401 tatctgtgca ggcggatctt gctaactatg ctttctttgc cattgaaagt ctgccagggc
     5461 agtttgacca gcgtgcagct tcgtcacagg aagccttgct tttgttggga agttcgagtg
     5521 acgtgacagt caacacagcc caactttact tggtgaataa agatattgat gcgactgagt
     5581 tggaagctgt caaaaactac ctgctcaatc cagttgattc tcgtttcaag gatatcacga
     5641 cagggattgc caagcaggag ttttcagagt cagacaagac cattccaaaa ttgactttct
     5701 ttgaaagcta tacagcagaa gactttgctc gctacaaggc cgagcaaggg atggccatgg
     5761 aagtggatga tttgctcttt atccaagact actttaagtc aatcgggcgc gtgccaactg
     5821 agactgaact caaggttttg gacacttact ggtctgacca ctgccgtcat acgacttttg
     5881 agacagagtt gaaacacatc gacttttcag cttctaaatt tcaaaagcaa ttgcagtcaa
     5941 cctatgacaa gtatattgcc atgcgcgagg agttaggtcg gtctgaaaaa ccacaaacct
     6001 tgatggatat ggcgactatt ttcggtcgtt atgagcgtgc taacggacga ttggatgata
     6061 tggaagtctc tgacgaaatc aatgcctgct cagttgaaat tgaagtggat gttgatggtg
     6121 tcaaggaacc ttggctcctc atgtttaaaa atgaaaccca caaccatcca acagaaattg
     6181 agccatttgg tggagcggct acctgtatcg gtggagctat tcgtgatccg ttgtcaggcc
     6241 gttcctatgt ttaccaagcc atgcgtattt caggtgctgg tgatattaca gcaccgattt
     6301 cggaaactcg tgctgggaaa ttgccacaac aagtcatttc taaaacagca gctcatggtt
     6361 attcttcata tggtaaccag attgggcttg ccacaaccta cgttcgtgaa tacttccacc
     6421 caggctttgt agctaaacgt atggaacttg gtgccgttgt tggtgcggct cccaagggca
     6481 atgttgtccg tgaaaaacct gaagcaggtg atgtgatcat ccttctcgga ggcaaaacag
     6541 gtcgtgatgg tgtcggtggt gcgacgggct cttctaaggt tcaaacagtt gagtctgtag
     6601 agactgctgg tgctgaggtt caaaaaggaa atgccatcga agaacgcaag attcagcgcc
     6661 tcttccgtaa tggcaatgtc actcgtctga tcaagaagtc caatgacttt ggggcaggcg
     6721 gcgtctgtgt ggctatcggt gaattggcag acggtcttga aatcgacctc aacaaggtgc
     6781 ctcttaaata ccagggcttg aatggtacag aaattgccat ctctgaatca caagaacgga
     6841 tggcggtcgt ggttcgtcct gaagatgtgg atgccttcgt tgccgaatgt aacaaagaaa
     6901 atattgatgc tgttgtggtg gcgacagtaa ctgaaaaacc aaatcttgtc atgcactgga
     6961 atggtgagac aatcgttgac ttggagcgtc gtttccttga caccaatggt gtgcgcgtgg
     7021 ttgtcgatgc caaagttgtg gacaaggatg tcaaactccc agaagagcgt caaacatctg
     7081 ctgaaacact ggaatcagat acccttacgg ttctatctga cctcaaccat gcaagtcaaa
     7141 aaggattaca gactgtcttt gactgctctg ttggacgctc aacggttaat cacccacttg
     7201 gtggtcgtta ccaactcaca ccaactgagg catctgtgca gaaattgcca gttcaacacg
     7261 gtgtgactca tactgcgtcg gtcattgctc aaggtttcaa cccatatgta gctgaatggt
     7321 ctccatacca cggtgctgct tacgcggtta tcgaagcaac tgctcgtttg gtggctgctg
     7381 gtgccaactg gtctaaggct cgtttctctt accaagaata tttcgagcgg atggacaagc
     7441 aagcagagcg ttttggtcag ccagtagccg cccttctagg ctctattgaa gctcagattc
     7501 aacttggctt gccatctatc ggtggtaagg actccatgtc tggtaccttt gaagaattga
     7561 ccgttccgcc aaccttggtt gcctttgggg tgacgacggc agatagccgt aaggtgctct
     7621 ctccagaatt taaagctgtt ggggaaaata tctactacat cccaggtcaa gccctctctg
     7681 cagagattga ttttgacttg attaagaaaa attttgctca gtttgaagca agccaggctg
     7741 accataaagt gacatctgca tcagctgtca aatacggtgg tgtagttgaa agtttggctc
     7801 ttgctacctt tggaaactat attggtgcag aggtgacctt gcctgaactt aaaacagctt
     7861 tgacagctca attaggcggc tttgtcttca catctcctga agaaattgct ggagtagaga
     7921 aggttggaca aacgaaagca gactttacac tgactgtcaa cggtgtgaag ctagatggac
     7981 acaagcttga cagtgcattt caagggacat tggaagaagt ttacccaaca gaatttaccc
     8041 aagcgaaaga actagaagaa gtaccagctg tggcatcaga tgttgtgatt aaagccaaag
     8101 aaaaggttga aaaacctgtg gtttacatcc cagtctttcc aggaaccaac tcagaatatg
     8161 attcagctaa ggcatttgaa aaagaaggcg cagaggtcaa cttggtgcca tttgtgacct
     8221 tgaatgaaga ggctattgtc aagtcagttg aaaccatggt tgacaacatc agtgaagcta
     8281 acattctctt ctttgcaggt ggcttctcag ctgcggacga accagatggt tcagctaagt
     8341 ttattgtcaa tatcctgctc aatgaaaaag tgcgtgcagc tattgatagc tttatcgctc
     8401 gtggtggctt gattatcggt atttgtaatg gattccaagc cttagtcaaa tcgggtctcc
     8461 taccatacgg aaactttgaa gatgctaaca gtactagccc aaccctcttc tacaatgatg
     8521 ccaaccaaca cgtggccaag atggtggaaa ctcgcattgc caataccaac tcaccatggt
     8581 tggctggtgt gcaagtgggc gatatccacg ctattcctgt ttcgcacggt gaagggaagt
     8641 ttgtcgtgac ggttgaggaa tttgcagagc tccgtgacaa tggacaaatt ttcagccaat
     8701 acgttgactt taacggtaaa ccaagtatgg attctaagta caatccgaat ggttctgtcc
     8761 atgccatcga aggaattacc agcaagaatg gtcaaatcat cggtaagatg ggccactcag
     8821 aacgttatga ggacggtctt ttccaaaata tcccaggcaa taaagaccag cacctgttcg
     8881 catcagcggt taaacatttc actggaaaat aagacttaca gattttctaa tagatagtat
     8941 cagtaatgta aaagtcatgt aaatctagct cttgatgatt acaaatgaaa attaggtata
     9001 aaaaatgaca tacgaagtaa aatctcttaa tgaagaatgt ggtgttttcg gtatttgggg
     9061 acatccagat gctgctaagt tgacctattt tggactccac agtcttcaac accgtggtca
     9121 ggagggggca ggaatcctct ccaatgatca aggacagctg aagcgccatc gtgacatggg
     9181 gcttttatca gaagttttca gaaatccagc caatttggat aaattgacag gagctggtgc
     9241 gattgggcat gtgcgttatg cgactgctgg cgaagcttct gttgataaca tccaaccctt
     9301 cctcttccgt tttcacgata tgcagtttgg tttggctcat aatggaaatc tgaccaatgc
     9361 agcctctctc aagaaagaac tggaacaaag aggagcaatt ttcagcgcga cttcggactc
     9421 tgaaatcttg gctcacctca ttcgtcgcag tcataatcct agcctgatgg gcaaaatcaa
     9481 ggaagcgctc agccttgtca aaggtggttt tgcctatatc ttgctgtttg aggacaagtt
     9541 gattgcggct cttgacccta atggctttcg tccgctttct atcgggaaaa tggccaacgg
     9601 agcggtggtt gtttcctctg aaacctgtgc ttttgaggtc attggtgccg agtggatttg
     9661 tgatttgaag ccaggtgaga ttgtgatcat tgatgacgag ggcattcagt atgacagcta
     9721 tacagatgat acccagttgg cgatttgttc tatggagtat atctactttg cccgccctga
     9781 ttctaatatc cacggtgtca atgtccatac ggcacgtaag agaatgggag cgcaattggc
     9841 gcgagaattt aagcatgagg cagatattgt agttggtgtg cccaattctt ccctaagcgc
     9901 ggctatggga tttgcggaag aatcaggctt accaaatgaa atgggtctga tcaaaaacca
     9961 atacacccag cgaactttta tccaaccgac tcaagaattg cgggagcaag gagtgcggat
    10021 gaaactgtct gctgtttcgg gtgttgtcaa aggcaaacgt gtggtcatgg tggatgattc
    10081 cattgtacgt ggaacaacct ctcgtcgtat cgttcagctc ttgaaagaag cgggtgcgac
    10141 tgaggttcac gttgccattg gaagtcctgc actagcgtat ccatgtttct acgggattga
    10201 tatccagacc cgtcaggagc tgattgcagc caatcatacg gtcgaagaaa ctcgccaaat
    10261 cattggtgcg gacagtctga cttatctttc aattgatagc ttgattgagt cgattggtat
    10321 cgaaacagat gcgccgaacg gtggtctctg tgtcgcttac tttgacggtg actacccaac
    10381 gcctctctat gactacgaag aagactatcg tagaagtttg gaagaaaaga ccagttttta
    10441 caagtaggcg acagattctc cattaaagaa aaggaaaaaa caaatgacaa ataaaaatgc
    10501 atatgcccag tcgggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa
    10561 gcacgtggcc cgtacggagc gtgcaggtgt catgggagct cttggtggct ttggtggtat
    10621 gtttgacctt tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt
    10681 cggaaccaag ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg
    10741 tgtggccatg tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga
    10801 ctacgtagcg acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc
    10861 agaaggttgt gtgcaggctg gtgctgccct catcggtggg gaaacggctg aaatgccggg
    10921 catgtacggc gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc
    10981 tcaaatcatt gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag
    11041 tgggattcac tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga
    11101 ggaagtccta ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg
    11161 tatctatgtc aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca
    11221 catcacaggt ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc
    11281 tgaaattgat gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg
    11341 tcagattaaa cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc
    11401 ggtcagccct gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat
    11461 tggtcgcatc gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt
    11521 tttgcctctg gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt
    11581 gtcttttcag accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg
    11641 tcctatgctt ttgaactcaa ggagtttgag agcaagacag actacgaagc agcccttgtc
    11701 gaactcttgg aagaacacca gattgacttg gtttgcctag caggctacat aaaaatcgtt
    11761 ggaccaacct tattgtcggc ttatgaaggt cggattgtca acattcatcc agcctacttg
    11821 ccagaatttc caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct
    11881 ggtgtgacca ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt
    11941 cgtgtgccac gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca
    12001 gagtacaggt tgtatccgga agtagtgaag gctctattta cagattgact ttttgatgat
    12061 tcatatgata tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg
    12121 aggtatttgt aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga
    12181 tgttattaac ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt
    12241 tcttagctcc aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa
    12301 aaattgtttt tgctgaaatg ttatttaatc tgattttctt tattccatta ggtgtttgtt
    12361 tccctttgat aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta
    12421 gtttattgtt tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt
    12481 tgactttaaa tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag
    12541 tgttcaaatc acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg
    12601 cttatcttgt tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga
    12661 atataatgac taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg
    12721 cccaagaact caaaaaactt ggttgggaga ttatctcaac aggtggaact aaggttgccc
    12781 ttgataatgc tggggtggat accattgcta tcgatgatgt gactggtttc ccagaaatga
    12841 tggacggtcg tgtgaagacc ctccacccaa atatccacgg agggcttctc gctcgtcgtg
    12901 acttggatag ccacttggaa gcggctaagg acaacaagat tgagctcatt gaccttgtgg
    12961 tggtcaacct ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg
    13021 cagttgaaaa tatcgatatt ggtgggccgt ctatgcttcg ttcagcagcg aaaaatcatg
    13081 ccagtgttac agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag
    13141 caaacggcga aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca
    13201 cagcggctta tgacgccttg attgcagaat acttcacagc tcaagtgggt gaaagcaagc
    13261 ctgaaaaact cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc
    13321 aacaagacgc ggacttttac cagaaagctt tgcctacaga ttactctatt gcttcagcca
    13381 aacagctcaa cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc
    13441 gtatcatccg tgacttcaaa gatagtccaa ccgttgtggc tctcaaacac atgaatccat
    13501 gtggaattgg tcaagctgat gacatcgaga ctgcttggga ctacgcttat gagtctgacc
    13561 cagtatctat ctttggtggg attgtcgtcc tcaaccgtga ggtggatgct gcgacagctg
    13621 agaagatgca cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc
    13681 tagccatttt gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc
    13741 aagaggctag cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa
    13801 atcaagacgt ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa
    13861 ccgagacaga agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa
    13921 atggtattat cgtgaccaac gaccacatga cacttggtgt tggtccaggt caaaccaacc
    13981 gtgtggcttc tgttcgcctt gccattgacc aagccaaaga tcgtctgaac ggggcggtcc
    14041 ttgcttcaga tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa
    14101 ttaaggccat catccagccc ggtggctctg tccgtgacca agaatccatc gaagcagcgg
    14161 ataaatacgg cttgactatg gtctttacag gtgtgagaca ttttagacat taagaagata
    14221 aaagggaaga aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta
    14281 aaacgaacgt ttatgttata atgttagtaa atgattcgta aaagaggttg agaaatgaaa
    14341 ctgcttgttg tcggttcggg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca
    14401 aaagacgtgg aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg
    14461 gaattggtaa atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat
    14521 gatgttgctt ggacctttat cggtccagat gatgcccttg ctgctggtat cgtggatgat
    14581 tttaaccaag ctgggcttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg
    14641 tccaaggatt ttgccaagga aatcatggtc aaatatggtg tttcgacagc agcctatggc
    14701 acattttcag atttcgagga agcaaaggcc tatatcgaaa agcatggtgc gcctatcgta
    14761 gtcaaggcgg atggcttggc gcttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa
    14821 gcggtcgaag ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc
    14881 gtggttattg aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt
    14941 gataagttct acatcatgcc aacggctcag gaccacaaac gtgcctacga tggcgacaaa
    15001 gggcctaaca cgggtggtat gggtgcctat gcgccagttc cacacttacc acagagtgta
    15061 gttgatacag cggttgacac cattgtcaag ccagttctag aagggatgat taaagaaggt
    15121 cgcccttatt tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc
    15181 attgagttca acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc
    15241 tctgactttg ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcatgtgg
    15301 acggacaagg gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagactat
    15361 gaaaggggcg ttgagttgcc agccaagaca gaaggcgatg tcatcaccta ctatgcaggg
    15421 gctaagtttg cggaaaatag cagagcactg ctctcaaacg gcggacgagt ttatatgctc
    15481 gttaccacag cagataccgt caaagaagcc caagccagca tctaccaaga actataccaa
    15541 caaaaaatag aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga
    15601 tataagaata acgcgccgta gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca
    15661 gaacagtgaa tgttctggtc aggggggaac ttggagaccg taggctcaaa gtttaggaat
    15721 gaaaccgaag gtttgcttac gcctccatca cctaagacca ttatcaaaaa gaaaaataaa
    15781 aattcacaaa atacgttaat gatcgtatgg tttgcgagcg ttagcgagct aatatagaac
    15841 aatcaccgcc gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa
    15901 gaccttgggt ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa
    15961 gctaaggtga ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc
    16021 atcatgggct caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc
    16081 ttcggtgtag cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc
    16141 aaacatgcag aagaagcccg tagtcgtggc atcaagatca tcatcgcagg tgctggtggc
    16201 gcagcgcatt tgccaggcat ggtagctgcc aaaacaaccc ttccagtcat tggtgtgcca
    16261 gtcaagtctc gtgctattag tggagtggat tcactctatt ctatcgttca gatgccgggt
    16321 ggggtgcctg ttgcgaccat ggctatcggt gaagctggag cgactaacgc agctctcttt
    16381 gccctccgtc tcctctctgt agaagataag tccattgcgg atgcacttgc caactttgct
    16441 gaagaacaag gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat
    16501 tatcggtggc ggtcaactgg gtcagatgat ggccatttct gctatctaca tgggccacaa
    16561 ggttatcgcg ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt
    16621 ggcaccttat aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac
    16681 ttacgagttt gaaaatgtcg acgctgacgg tttggatgcc gttatcaagg atggacaact
    16741 ccctcaagga acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt
    16801 gtcaaacaag gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt
    16861 ggcagatatc gacttgtcga aaaactatgt cctcaagact gcgactggtg gctacgatgg
    16921 tcatggacaa aaggttattc gttcagaagt agacttggaa gcagcctatg cgctagcaga
    16981 ctcagcagac tgcgtcttgg aagaatttgt caactttgac cttgagattt ctgtcatcgt
    17041 gtcaggaaat ggcaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa
    17101 tatcctgtct aagaccatcg taccagcccg catttctgaa agtctagtag acaaggctaa
    17161 agctatggca gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat
    17221 gtttgcgact gatgatgacg ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg
    17281 gcactattct attgaagcct gtgatttctc tcagtttgac acccatattc tcggtgttct
    17341 cggagcacca ttaccagtca tcaaactcca tgcgccagcc gttatgctta atgtcctcgg
    17401 tcagcatgtc gaggctgctg agcaatatgt gacagaaaat tcaagcgccc acctccacat
    17461 gtatggtaaa atagaagcga agcacaaccg caagatggga catgtgacct tgtttagtga
    17521 tgtaccggat agtgtggatg agcttgggga agggattgat ttttaggaca agtctatgat
    17581 acaaattatc gttaatacat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt
    17641 gtatgccagt gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata
    17701 ccccgaaaat tatttagcta tctatgatgt accgctggat acggatttga atacactaga
    17761 tcattacccg tctgtgttta ttgaaaaaga ggagtttgag tagaaatctt ggtttaccta
    17821 gatagcttat tcccaacagc ttaagaagaa aggaaaaatt aacacatgat caaccgttac
    17881 tctcgccctg agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag
    17941 gtggaaatcc tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg
    18001 gctttgattc gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag
    18061 acgcgccacg atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc
    18121 aagtgggttc actatgggtt aacttctacc gacgtggtgg atactgctta tggttacctc
    18181 tacaagcagg ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct
    18241 gacaaggcca aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct
    18301 gagccgacaa cctttggtct taaattggca acttggtaca gcgaaatgaa acgcaatatc
    18361 gagcgtttcg agcatgcagc tgctggtgta gaagctggta agatttctgg tgcggttggg
    18421 aactttgcca atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt
    18481 gcccaagaaa tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt
    18541 cttgccagca ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa
    18601 tctgagcaac gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg
    18661 cctcacaaac gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt
    18721 ggtcacatga ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac
    18781 tcatcagctg agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac
    18841 cgttttggaa atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg
    18901 aactcgactt ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc
    18961 atgacccgtg agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac
    19021 caagtagact ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa
    19081 gaagaaatcg atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt
    19141 gaacgtcttg gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt
    19201 attttttatc gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt
    19261 ggacatgagt cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt
    19321 tttctctgtt accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc
    19381 agttgatgga gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc
    19441 ttgtccgttt tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac
    19501 ggcttcctgt gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt
    19561 gctcacagag tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt
    19621 tcctttgagt aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg
    19681 gatatccagt ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg
    19741 agttacagga gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc
    19801 aaggactgtt tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc
    19861 acctttgact cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt
    19921 cttgataact tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac
    19981 attggcagcc acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc
    20041 ttgaagagcg gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt
    20101 gaggttgtaa tttagagctg ttttagctgc gtcaagggcc tcaagacttt ctttactata
    20161 tccttctaag tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg
    20221 gaagtagtct ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt
    20281 gtactcagcg cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc
    20341 tacttcagga tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat
    20401 agctttcttg aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc
    20461 accgttggta ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt
    20521 atatccccac cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc
    20581 gtccttgtct tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt
    20641 ggccatagct gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt
    20701 gaggtagtac cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt
    20761 gaaaatcttt gttttacctg caaagaagtc catgtattta ccgatgaggg cttttacaaa
    20821 gttcatcgct tcttcgtttt ttaagtccat agttgttttt gaaactttat caaagtgggc
    20881 ttgaggattt ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg
    20941 actgttaata gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt
    21001 tacttctgcc tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc
    21061 gataatagct tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat
    21121 atcatcgagt agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc
    21181 gagctcactg gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc
    21241 agcatcgatt gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc
    21301 ttcttttaga gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat
    21361 ggcttgatca atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc
    21421 tttttcagct tcttttacgg ccgcgacgct ttctgcagta taacggttca ggtcttttgg
    21481 tacctcgtta agtgtttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc
    21541 atttgcaaaa tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt
    21601 gtcagcccaa gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg
    21661 tacagaagtg attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc
    21721 ttggccatca gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg
    21781 gtgacctttt tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt
    21841 ccacatagaa acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta
    21901 gataccgtcg ttaaaagcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc
    21961 attggcgtag gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta
    22021 tttatcagct tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc
    22081 aagtccgatg ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag
    22141 ggcttttgta aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt
    22201 cccaaaatag ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc
    22261 atccatgtgt ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata
    22321 gttaatcaga tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata
    22381 atcatttgta cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt
    22441 agctgtgatg ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg
    22501 taaatcagtg tagccataat gtttcgcttt atcgatgatt tccttgagtt gttctggtga
    22561 gaaatattta cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac
    22621 agttgcagca cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc
    22681 atctttttta gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac
    22741 ctctttcgct tcttcctttt taggactagc ttcttctgcc tttttattag cagtttcttt
    22801 ttcagcagaa gttggagtta ccacttctgc tttatcacta ggagttgaac taacttcctc
    22861 ttgtggtttt tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt
    22921 ttctacagtt tttggagctt ctggttgaag cactgcttta ggtgtttcct cagtccgatt
    22981 ttcggatgat tgaggggaat cagaaaccgt atggatggtc ggttggtttt ctgtagtagt
    23041 aggagtaact ccatcggctg caacagtctg tgcttggaag gcaaatccaa ttagaacaga
    23101 agctgctcct acagcgtatt tacgaataga aaaacgctgt tgtttttcat gtttcattgc
    23161 aaaacctcct gattgcattg ttatattgat agcgattata taaatcaacg cctttatttt
    23221 atttcttata ttaacgagag tcaagaggag atgacaaaaa actataataa gtataaaaaa
    23281 atataaaatt taaacttaag atttcagatt ggtcggaaaa aatgaatata tatatctagt
    23341 ataatttttg gttctatttc tataaaatat tccacaaatt atagaatctt ccaaaaatag
    23401 gtaagcgcta cctttttggt gtggtataat aagcatagaa aaagcccaag cgattagctc
    23461 aggctttctt cttagtgatc acggtcacat gagataaatt taatcttgta gtaatcagat
    23521 cgtttgtaag tttcactgta ttctaaaact tggccagttg attcgagttt ggtgatttta
    23581 gtttgtagga cagtagggaa ttgttcatcg actccgagga ctgaagccgc atgttctgga
    23641 gttggaaaga ctatttcgtt gatttcttca aagtgttcat cattcatgtg aatgtggtag
    23701 tctaacttga aacgattata gatagaacta tagtattcaa ggtttggata atttgcgttg
    23761 atatattgtt ctgggatgta ggatgtatgg tagatataaa cgacaccgtt tgattcgcgg
    23821 atacgttcaa tcttgtagta gaattgatcg ccgcgtagac ccaatttttc caagtaaaca
    23881 agcttgtttc cgcgttcaat tgaaagaaca gttaccttat catctttagc attgaagagt
    23941 tcaatatctg aaaactctac aagcttgtgt ttgcgcgcac gtgaaacgaa ggttcctttt
    24001 ccttgttggc ggacaatata gccatctttg gcaaggtcgt ttaaggcgcg aacaactgtg
    24061 atagagctga catcgtacat tgaaatgagt tctgcttcag tgtaaaattt atctccactg
    24121 ctaaactgcc cagagatgat tttatttttt aattcgtctt ttatgtattg atatttggga
    24181 attgccatat ttttacctct attttccttc tccatagaaa attttaccat aaaagcgaaa
    24241 aaaatagtag tcttttgaat aaaaaattag aataatagtt tgaaaaatta agcgatatag
    24301 ggattgctca tattttataa atgtattcta tacaaaatta ttttaggtcc tatattccga
    24361 atttaaagag cgtttgaaat gggtctaaaa atgtttgaaa ctaattgaat gtgtgtataa
    24421 tagtaaaaat gcagtaaata tcccgacaat ttctattgac aattcaaaca gattggttta
    24481 taattaatat aacaacaagt gaaagcgcaa actttcgcgg tcggaaggta gttttatgac
    24541 acgatttgag atacgagatg atttctatct cgatggaaaa tcatttaaga ttttatctgg
    24601 tgccattcat tattttaggg ttcctccaga ggattggtat cattcgctct ataacttgaa
    24661 ggctcttggt tttaatacgg tagagactta tgttgcttgg aatttacacg agcctcgtga
    24721 aggtgagttt cattttgaag gtgatctgga tttagagaaa tttctccaaa tagcgcagga
    24781 tttgggtctc tacgcaattg tgcgtccgtc tccatttatc tgtgcggaat gggaattcgg
    24841 tggcttacca gcttggctct tgaccaagaa catgcgaatt cgctcatccg acccaacata
    24901 tatcgaggca gttggtcgct actatgatca gttattgcca agactggttc ctcgtttgtt
    24961 ggacaatggt ggcaatattc tcatgatgca ggttgaaaat gagtatggtt cttacggaga
    25021 agataaggct tacctgagag cgattcgaca gctaatggaa gagtgtggcg taacctgtcc
    25081 cctctttaca tcagatggtc catggcgagc tactctgaaa gctggaacct taattgaaga
    25141 ggacctcttt gtaacaggaa actttggttc taaggcacct tacaactttt cgcagatgca
    25201 ggaattcttt gatgaacatg gtaagaaatg gccactcatg tgtatggagt tctgggatgg
    25261 ttggtttaat cgctggaaag aaccgattat cacacgggat cctaaggaat tggcagatgc
    25321 agttcgagag gttttggaac aaggctctat caatctttac atgttccacg gtggtacaaa
    25381 ctttggtttc atgaatggtt gctcagctcg aggaactttg gacctgccac aagttacgtc
    25441 ttatgattac gatgcccttc tggatgaaga aggaaatcca actgctaaat atcttgcagt
    25501 caagaagatg atggcaacac atttttcaga gtatccgcag ttggaaccac tctacaaaga
    25561 gagtatggag ttggatgcta ttccactagt tgaaaaagtt tctttgtttg aaaccttaga
    25621 tagcttgtca agtcctgtag aaagtctcta tcctcaaaag atggaggagc tgggacaaag
    25681 ttatggctac ctactttatc gaacagaaac aaactgggat gcagaagaag aaagacttcg
    25741 tatcattgat ggtcgagata gggcccagct gtatgtcgat ggtcagtggg ttaaaactca
    25801 atatcagaca gagattgggg aagatatttt ttatcaaggt aaaaagaaag ggctatctag
    25861 gttagatatc ttgatagaaa atatggggcg tgtcaactat gggcataagt tcttagcgga
    25921 tacgcaacgt aagggaattc ggacaggggt ctgtaaggat ctgcatttct tactaaactg
    25981 gaaacactat ccactcccac tagacaatcc tgagaaaatt gatttttcaa aaggatggac
    26041 tcaaggacaa ccagcctttt acgcttatga ctttacagtc gaagagccaa aagatactta
    26101 cctagacttg tctgagtttg gtaagggggt tgcctttgtc aatgggcaga atctaggacg
    26161 tttttggaac gttggcccaa ctctctcact ttatatccct catagctatc tcaaggaagg
    26221 tgccaaccgc atcattatct ttgaaacaga aggtcaatat aaagaagaga ttcatttaac
    26281 tcgtaaacct acactaaaac atataaaggg ggaaaactta tgacaattgt aggatgccgt
    26341 attgatggac gtttgatcca cggacaagta gccaatcttt gggctggaaa actaaatgtt
    26401 tcacgcatta tggttgtaga cgacgaagtt gtcaacaacg atattgaaaa gagtggtttg
    26461 aaacttgcga caccaccagg tgtgaaattg agtattttgc cagttgagaa agctgcagcc
    26521 aatattcttg ctggcaaata cgatagccaa cgtctcttta tcgtggctcg taaaccagac
    26581 cgcttccttg gtttggtaga agcaggtgta ccacttgaaa cccttaatgt tgggaatatg
    26641 tctcaaacac cagaaactcg ttctattaca cgttctatca acgtagtaga caaggatgtg
    26701 gaagacttcc acaaactggc agaaaaaggt gttaaactta ctgctcagat ggttccaaat
    26761 gatccaattt cagacttttt gagcttatta aaataggaaa aaaattttta ggaggtcatt
    26821 gttatgatac aatggtggca aattttactt ctcactttgt actcagctta tcaaatctgt
    26881 gatgagttga cgatcgtttc atctgcaggt tcccctgtat ttgctggttt cattactggt
    26941 ttaatcatgg gagatgtgac tactggttta cttatcggtg gtaacttgca actgttcgtt
    27001 cttggggttg gtaccttcgg tggtgcttct cgtatcgacg caacttctgg tgcggttctt
    27061 gcgacagcct tctctgtttc acaaggaatt gatgcaccgc ttgcaattac tacaatcgct
    27121 gtaccagtag cagctctctt gacttacttc gacgttcttg gtcgtatgac tactaccttc
    27181 ttcgctcacc gtgtggatgc tgcaatcgaa cgctttgact ataaaggtat tgaacgcaac
    27241 tacttgcttg gtgcgattcc gtgggctcta tctcgtgccc ttccagtctt ctttgccctt
    27301 gcttttggtg gtgcctttgt acaatcagta gtagacttcg ttgaagccta caaatgggtt
    27361 gcagatggct tgacactcgc aggacgtatg cttccaggtc ttggatttgc aatcttgctt
    27421 cgttaccttc cagttaaacg taaccttcac taccttgcta tgggatttgg tttgacagct
    27481 atgttgactg ttctttactc atatgtaaca ggtcttggtg gcgctgttgc tggtatcgta
    27541 ggtactcttc ctgctgaagt tgctgaaaaa attggtttcg tgaacaactt caaaggtttg
    27601 tctatgattg gtatttctat cgtaggtatt ttccttgcag tgcttcactt caaaaatagc
    27661 caaaaagtag ctgtagcagc accttctaca ccatcagaaa gtggggaaat cgaagatgac
    27721 gaattctaat tacaaactta caaaagaaga ttttaatcaa atcaacaaac gtagcttgtt
    27781 tactttccaa ttaggttgga actacgaacg tatgcaagct tctggttacc tttacatgat
    27841 cttgcctcag ttgcgtaaaa tgtatggtga tggaactcct gaattgaaag aaatgatgaa
    27901 agttcatact caattcttca atacttcacc attcttccat accattatcg ctggttttga
    27961 ccttgccatg gaagaaaaag atggtgtagg ttcaaaagac gccgttaacg gtatcaagac
    28021 aggtttgatg ggaccattcg ctcctcttgg ggatacaatc tttggttcac ttgtacctgc
    28081 tatcatgggg tcagtcgcag caactatggc tatcgctggc caaccttggg ggatcttcct
    28141 ttggattgca gttgcagtag cgtatgacat cttccgttgg aaacagttgg aatttgctta
    28201 caaagaaggg gttaacctta tcaacaacat gcaaagtacc ttgacagctt tgattgacgc
    28261 tgcatctgta cttggtgtct tcatgatggg tgctcttgta gcaacagtga ttaactttga
    28321 aatttcttac aagttgccaa tcggtgaaaa gatgattgat ttccaagaca tcttgaatca
    28381 aatcttccca cgtttgcttc cagcaatctt tactgccttt atcttctggt tgcttggtaa
    28441 gaaaggtatg aactctacta aagctatcgg tattattatc gtacttgctt tggctctttc
    28501 tgcccttggt cactttgcac ttggaatgta attccttatg actaaatcat taattttggt
    28561 gagccatggt cgcttctgtg aggagcttag aggtagcaca gaaatgatta tgggcccaca
    28621 agacaacatt tacacagtag ctcttcttcc agaagatggc ccagaagaat ttactgctaa
    28681 atttgaagct gttattgaag gattggatga tttcctagtc tttgcggatc ttctcggtgg
    28741 gacaccttgt aatgtggtga gtcgcttgat catggaaggt cgtgatattg acctttacgc
    28801 agggatgaat cttccaatgg tgattgaatt tatcaatgcg agccttacag gcgcagatgc
    28861 ggactacaag agccgtgctg cagaaagcat tgtgaaagtt aatgacctgt tagcgggctt
    28921 cgatgatgac gaagatgaat aatactcttc gaaaatctct tcaaactacg tcaacgtcgc
    28981 cttgccgtag gtatatgtta ctgacttcgt cagtcttatc cggcaacctc aaagcagtgc
    29041 tttgagcagc ctgcggctag tttcctacag attttagttg gaactcgatt caattcatgt
    29101 gacaacgtga aaatcgttag agcattttat atagaatata catgggaatg tagcttactc
    29161 ccattcccat atttaataga aaaagaggaa ctcaatgcta cattatacaa aagaagactt
    29221 gctcgaattg ggtgcagaaa tcactacgcg tgaaatctac caacagcctg atgtatggag
    29281 agaagctttt gaattttatc aagcaaaacg tgaagaaatt gcagccttcc tacaagaaat
    29341 cgctgataaa catgactata ttaaggttat cttgacaggt gctgggactt ctgcttatgt
    29401 gggagatacc ttgctacctt attttaagga agtctatgac gaacgcaaat ggaatttcaa
    29461 tgctattgcg acaacagata tcgttgccaa tccagcaacc tatttgaaaa aagatgtggc
    29521 aactgtcctt gtgtcttttg ctcgtagtgg gaattcgcct gaaagtttgg cgactgttga
    29581 tttggccaaa tccttggtgg atgagcttta tcaagtgacg attacttgtg cagcagatgg
    29641 taaattggct cttcaagctc acggtgatga tcgtaatctc ttgctcttgc aaccagctgt
    29701 ctctaatgat gctggatttg ccatgacttc tagctttacg tctatgatgt tgacaactct
    29761 cttggtcttt gatcctacag aatttgctgt taagtctgaa cgttttgaag ttgtatctag
    29821 tcttgcccgt aaagttttag acaaggcaga agatgtcaaa gagctcgttg atttagactt
    29881 taaccgtgtc atctatctag gcgctggtcc tttctttgga cttgctcatg aagctcagct
    29941 caagattttg gaattaactg ctggtcaagt tgcgaccatg tatgaaagcc cagttggctt
    30001 ccgtcacggt ccaaaatctc ttatcaacga caatacagtt gttttggtct ttggtacaac
    30061 gacagactac actcgtaagt acgacttgga cttggttcgt gaagttgctg gtgaccagat
    30121 tgctcgtcgt gttgtgcttt tgagtgatca agcttttggt cttgaaaatg tcaaagaagt
    30181 ggcccttggt tgtggcggtg tcttgaatga tatttaccgt gtcttccctt acatcgttta
    30241 tgcccaactc tttgctttat tgacttcact caaggtagaa aataaaccag atacaccgtc
    30301 tcctacaggt acagtaaacc gtgtagtaca aggtgtcata attcacgaat atcaaaagta
    30361 agacagtgtt tatgaattct tgacaagagg atttgtaaat tatcagataa accatagatt
    30421 gtcagtacgc tttctatggt ttgtttgctt gagagaaata gtaaaaggag aacagaatga
    30481 aagcatacac agagcgtgta tttggaaatg ttgagggtga ggatgtcttg gcctatcgat
    30541 ttgagacaga cggtggctac caacttgagg ttatgactta tggtgcgact atcttgcgct
    30601 atgtcgcacc tgacaaggct ggaaattttg ccaatgttat cttgggattt gatgactttg
    30661 atagttatgt aggcaatagt cccaagcatg gagcaagtgt aggtcctgta gcgggtcgta
    30721 ttgcaggtgc gacctttgag ctcaatggta agacctatga ccttgaggtt aataatgcta
    30781 gcaactgtaa tcacagtggt tcaactggtt gggattccag cttgtttgaa gttgaagaag
    30841 taagcgatca tggcttgact ctctacacag agcgtacaga tgggacagga gggttccctg
    30901 gaaatctcaa gatttggatc agttatcact tggaagaaac tggtgcctat gaaatcagct
    30961 acaaggtaac gaccgatcag gatacgctgg tcaatccaac caaccacagc tatttcaact
    31021 tgtctggtga tttcacgcag acgattgacc gtcatgtctt ccaactaaac acagagggca
    31081 tttactcaat cgctcctgac ggtgttcctg ccaaaactcc agaagccaac cgtgatgtgg
    31141 tcaaacacgt ctacaatggt accttgttga aggatatctt tgcagaagaa gatgagcaaa
    31201 tccagctggc atcaggtttg gatcatccat ttgcccttcc tgcaggccat gacaatgctg
    31261 gattccttta tgaccaaaat tcaggtcgct tcctgctttt caagacagaa gctccttgct
    31321 ttgtggtcta cacagcaaac tttgtggatg aaagtgtcat cataggaggt cagccaatgc
    31381 tacagcacaa tgggattgct cttgaagcgc aagctttacc agatgccatt cacagtgacc
    31441 ttaaaggcca agtcattctt aaagctggtc aaaccttcac cagtaagaca cgttatgaac
    31501 ttgttgtgaa ataaaaaaag ctggtcaaaa agtctttaaa attaaaataa cgcatattgt
    31561 caggtgatga aaagtttgat aatatgcgtt ttattatgaa atgatttact ttatattatc
    31621 ctgaaatggt gttatttttg agttatctgg cttgactttc ttgatggaaa ttatataata
    31681 gttgtaacaa taataattac aactagaaaa gaggaccatt tatgacctat gaatacaaga
    31741 gtcacattta tttggcagag acagctttaa atgtaaagga tttggccagt caaacagcct
    31801 tttatcagca agttattggt ttagaaatat tatctcaaac tgagacagag tccattctag
    31861 gccttggtgg aaaagtcttg gtacagctga ttcaagcaca agagagcgga gaagtgaggg
    31921 aatattatgg tctttaccat ttggccattc tcttgcccac acgcaaggct ttagctgatg
    31981 tcttgaaacg cctgacagat ttacaaattc ctcttgtcgg cggtgcagac catggttaca
    32041 gtgaagctat ttacttggaa gatttggagg gaaatggcat tgaactctat cgagataagc
    32101 cagtttccac atgggatatt cgagaagatg gacgcattat cggagtgacg gaggctcttg
    32161 cggcgcagga catttatgag ttgggggaaa gagtagagcc ctttatcctg gcagaaggta
    32221 caagaatggg gcatattcat ctttccgtca aggatagtcg aaagtccagc cagttttatc
    32281 aaaaggtgtt agggctagag aataaattca gtgtgcctgg cgctagttgg attgcggctg
    32341 gagattacca tcatcattta gcagttaacg aatggggagg aaaaggtctg gcttcgcgta
    32401 agcaaggctt accaggttta gcctactatg tcatcgaagt cgcacataaa aaagaactgt
    32461 taacgattgc ccaacgagca caagaagttg acgcaccaat caaatggatg acatcgatcc
    32521 aattggaaat cacagactca gatggcatcg tgacccgtat tcgtttagca aggtaaaatt
    32581 aggaattttt aataagttat aagtattgct agtttgcttt ttgaacggtc tttggtaaca
    32641 gaactgcgtg agaattttga caaagaagct gattagagat ataatgaaga aaaatcgagc
    32701 aaggaaaaag aactgacaaa ttcaaagtat attacttgtt tgaaacgttc agagggccag
    32761 ttgtgtggga ttcaaaagat gattgaagga gatcgtgact gtgctgatat tgtgacgcaa
    32821 ctgacagcag tgaaatctag tgtagagcgc gtgattgaga tgataattac cgaaaatctt
    32881 actgaatgta tcaatcagcc cctagatgat tctgaagctc aaaaggaacg cctagaaaag
    32941 gctatccgat acttgattaa acggaaataa atgaatgttt tgagacgata tgtgcaaagg
    33001 tctattaact attagaatag tttaatgtga gtcaaaagaa gttgtaaaaa atctttaaaa
    33061 ttaaaaaaac gcatagtatc aggtgttgaa tgtactgacc cccaaaagtt agattttttc
    33121 tgtctaactt ttggggtgca gttcataaga accttggtaa tatgcgtttt attatgtaga
    33181 gacttatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtagatatgg
    33241 ttactgactt cgtcagttct atccacaacc tcaaaacagt gttttgagct gacttcgtca
    33301 gttccatcca caaccttaaa acagtgtttt gagcagcctg cggctaactt cctagtttgc
    33361 actttgattt tcattgagta ttacttcatc ttttcctgaa attgagtttt tgcccaactc
    33421 ctcttgatta ttctacttga ccgggccaag cattcatacc accttctacg ttggtaacgg
    33481 tgaggccttg ggagctgaga aactggcagg tagatgcaga gcggactcct ccttgacaaa
    33541 tgacatagta ttcatggtca ggtttgagtt ctttgtagcc ttgctctaag gtacttaatg
    33601 gaagattttt ggcacctggt gcatgtcctg cttggaattc atgtgcttca cggacatcga
    33661 taagttctag attttcattt tggtattttc cataaaagtc agccatgctg atactagttt
    33721 ccatattcta ctccttctgg gttaaccatt ttgtatagtg aataagcgcc gtcaaggttt
    33781 tgggcggtaa atcctgcttg cttgaggata ggctctgcga tatagctgcg caaaccactg
    33841 tggcagctga cgatgtaggc ttgttttttg tccagttcat cagtttcctc cttgacactt
    33901 tgtcagtttt tgatacaata gtacaaaatt agaggaggca ggctatgatt cagaaacatg
    33961 cgattcctat tttagagttt gatgacaatc ctcaggcggt tatcatgccc aatcacgagg
    34021 ggctggactt gcagttgcca aagaagtgtg tttatgcatt tttaggtgag gagattgacc
    34081 gctatgcaag ggaagtaggg gcggattgtg tcggcgaatt cgtttctgct accaagacct
    34141 atccagtcta tgtcatcaac tacaagggtg aggaggtctg tctggctcag gctcctgttg
    34201 gctccgctcc agcagcccag tttatggatt ggttgattgg ctatggtgtg gagcagatta
    34261 tctctactgg gacctgtggt gtcctagctg atatagagga aaatgccttt ctagtccctg
    34321 ttcgcgcttt gcgagatgag ggagccagtt accactatgt ggcaccttgt cgttatatgg
    34381 aaatgcagcc agaggctatt gctgctattg aggaagtttt ggaagacaga gggattcctt
    34441 atgaagaagt catgacctgg acgacagacg gtttttaccg agaaacggct gaaaaggtgg
    34501 cttatcgtaa ggaagaaggc tgtgctgttg tggagatgga gtgttctgct cttgcggcag
    34561 tagctcaatt gcgtggggtt ctctggggtg aattgttgtt cacagcagat tctctagcgg
    34621 acttggacca gtacgacagt cgtgactggg gctcggaagc ttttaataag gcgctagaac
    34681 tgagtttagc aagtgttcac cacctttagt tgtactggca aaggatttgt tttatcataa
    34741 aatgtctagc tcatactttt caaaaatatg tttaaacgag gtcaccttcc tcttgtccta
    34801 ggcatgttga ggttgggaaa aatctttaaa atcagaaaaa cgtatcatat caggtgatga
    34861 aaactttgat actatgcgtt ttatgttggt aagatttaga gtgagatgaa atgatactct
    34921 tcgaaaatct tttcaaacca ggtcagcttc accttgccgt atagatgtta ctgacttcgt
    34981 cagttctatc tgcaacctca aaacagtgtt ttgagctgac ttcgtcagtt ctatccacaa
    35041 cctcaaaaca gtgttttgag ctgacttcgt cagttctatc cacaacctca aaacagtgtt
    35101 ttgagctgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag caacctgtga
    35161 ctagctttct aagcgatgcc ttggttctca ttgcctataa tcaaaaagag aaattttctc
    35221 ctgaaaagca tatagagtag ctggcgttaa aagctcctgt cttgcttttt tgacctatag
    35281 tcacatctat caagtattgt tcttgcctaa gctatcaata aaaaggtggc attttttagg
    35341 cttggtgtta gtgaattttg ccttatccta tctaagtcat ttcgagcttt ttatggtaca
    35401 atggaaacat gttattcaaa ttatctaagg aaaaaataga gctaggctta tctcgtttat
    35461 cgccagcccg tcgtattttt ttgagttttg ccttggtcat tttactagga tctcttcttt
    35521 tgagcttgcc ctttgtccaa gttgaaagct cacgagcgac ttattttgat catcttttca
    35581 ctgctgtctc tgcagtctgt gtgacaggtc tctcaaccct tccagtagct cacacctata
    35641 atatatgggg ccaaataatc tgtttgctct tgattcagat cggtggtcta gggctcatga
    35701 cctttattgg ggttttctat atccagagca agcaaaagct tagtcttcgt agccgtgcaa
    35761 ctattcagga tagttttagt tatggagaaa ctcgatcttt gagaaagttt gtctattcta
    35821 tttttctcac gacctttttg gttgagagct tgggagctat tttgcttagt tttcgcctta
    35881 ttcctcaact tggctgggga cgtggtcttt ttagttccat ttttctagcg atctcagcct
    35941 tctgtaatgc cggttttgat aatttaggga gcaccagttt atttgctttt cagaccgatt
    36001 tactggtcaa tctggtgatt gcaggcttga ttattacagg cggccttggt tttatggtct
    36061 ggtttgattt ggctggtcat gtaggaagaa agaaaaaagg acgtctgcac tttcatacga
    36121 agcttgtact attgttgact ataggtttgt tgttatttgg aacggcaact actctctttc
    36181 ttgagtggaa caatgctgga acgattggca atctccctgt tgccgataag gttttagtta
    36241 gcttttttca aacagtgacg atgcgaacag ctggcttttc tacgatagat tatactcagg
    36301 ctcatcctgt gactcttttg atttatatct tacagatgtt tctaggtggg gcacctggag
    36361 gaacagctgg gggactcaag attacgacat tttttgtcct cttggtcttt gcacgaagtg
    36421 agcttctagg cttgcctcat gccaatgttg cgagacgaac gattgcgccg cgaacggttc
    36481 aaaaatcctt tagtgtcttt attatctttt tgatgagctt cttgatagga ttgattctgc
    36541 tagggataac agccaaaggc aatcctccct ttatccacct catatttgaa accatttcag
    36601 ctcttagtac agttggtgta acggcaaatc tgactcctga ccttgggaaa ttggctctca
    36661 gtgttatcat gccacttatg tttatgggac gaattggtcc cttgaccttg tttgttagct
    36721 tggcagatta ccatccagaa aagaaagata tgattcacta tatgaaagca gatattagta
    36781 ttggttaaga aaggaaagag catgtcagat cgtacgattg gaattttggg cttgggaatt
    36841 tttgggagca gtgtcctagc tgccctagcc aagcaggata tgaatattat cgctattgat
    36901 gaccacgcag agcgcatcaa tcagtttgag ccagttttgg cgcgtggagt gattggtgac
    36961 atcacagatg aagaattatt gagatcagca gggattgata cctgcgatac cgttgtagtc
    37021 gcgacaggtg aaaatctgga gtcgagtgtg cttgcggtta tgcactgtaa gagtttgggg
    37081 gtaccgactg ttattgctaa ggtcaaaagt cagaccgcta agaaagtgct agaaaagatt
    37141 ggagctgact cggttatctc gccagagtac gaaatggggc agtctctagc acagaccatt
    37201 cttttccata atagtgttga tgtctttcag ttggataaaa atgtgtctat cgtggagatg
    37261 aaaattcctc agtcttgggc aggtcaaagt ctgagtaaat tagacctccg tggcaagtac
    37321 aatctgaata ttttgggttt ccgagagcag gaaaattccc cattggatgt tgaatttgga
    37381 ccagatgacc tcttgaaagc agatacctat attttggcag tcatcaacaa ccagtatttg
    37441 gataccctag tagcattgaa ttcgtaaaga gggatgaccc ctcttttttg atgcccaaga
    37501 tggcaaatag agacagaagc cccttgtctt ctagtaaaag ttcttcaaag gctggacttt
    37561 atggtaaaat agaaggaagt gacaagagag agtaatactc aatgaaaatc aaagatcaaa
    37621 ctaggaaact agctgcgggc tgctcaaaac actgttttga ggttgtggat agaactgacg
    37681 aagtcagctc aaaacactgt tttgaggttg cagatagaac tgacgaagtc agctcaaaac
    37741 actgttttga ggttgcagat agaactgacg aagtcagtaa catctatacg gcaaggcgac
    37801 gttgacgtgg tttgaagaga tttttgaaga gtataagaaa aaatcagtcc cctaaaggag
    37861 tagattatga agttattgtc tatcgccatt cccagctata atgcagcagc ctatcttcat
    37921 tactgtgtgg agtcgctagt gattggtggt gagcaagttg ggattttgat tatcaatgac
    37981 gggtctcagg atcagactca ggaaatcgct gagtgtttag ctagcaagta tcctaatatc
    38041 gttagagcca tctatcagga aaataaatgc catggcggtg cggtcaatcg tggcttggca
    38101 gaggcttctg ggcgctattt taaagtagtt gacagtgatg actgggtgga tcctcgtgcc
    38161 tacttgaaaa ttcttgaaac cttgcaggaa cttgagagca aaggtcaaga ggtggatgtc
    38221 tttgtgacca attttgtcta tgaaaaggaa gggcagtctc gtaagaagag tatgagttac
    38281 gattcagtct tgcctgttcg gcagattttt ggctgggacc aggtcggaaa tttctccaaa
    38341 ggccagtata ccatgatgca ctcgctgatt tatcggacag atttgttgcg tgctagccag
    38401 ttctaactgc ctgaacatac tttttatgtc gataatctct ttgtctttac gccccttcag
    38461 caggtcaaga ccatgtacta tctgcctgtc gatttctatc gttatttgat tgggcgtgag
    38521 gaccagtctg tcaatgagca agtgatgatt aagtgcattg accagcaact caaggtcaat
    38581 cgactcttgg tagaccaact tgatttgtcc caagtgagtc atcccaaaat gcgagaatat
    38641 ctgctgaatc atattgaaat cacgacggtg atttccagta ccctgctcaa ccgatctgga
    38701 acaacggagc atctggcaaa aaaacgccaa ttgtggacct atattcagca gaaaaatcca
    38761 gaagtctttc aggctattcg taagaccatg ttgagccgtt tgaccaaaca ttctgtcttg
    38821 ccagatcgca aactgtccaa tgtcgtctat caaatcacca aatctgttta tggatttaat
    38881 taatataagt gttttataag agggatttaa gaaaaatttt aactttttct tagtcctttt
    38941 taatttcagg agattatact agagtcatca aataaagaaa gactctaagg agaatcctat
    39001 gaaattcaat ccaaatcaaa gatatactcg ttggtctatt cgccgtctca gtgtcggtgt
    39061 tgcctcagtt gttgtggcta gtggcttctt tgtcctagtt ggtcagccaa gttctgtacg
    39121 tgccgatgtg gtcaatccga ccccaggtca agtcttacct gaagagacat cgggaacgaa
    39181 agagggtgac ttatcagaaa aaccaggaga caccgttctc actcaagcga aacctgaggg
    39241 cgttactgga aatacgaatt cacttccgac acctacagaa agaactgaag tgagcgagga
    39301 aacaaactct tctagtctgg atacactttt tgaaaaagat gaagaagctc aaaaaaatcc
    39361 agagctaaca gatgtcttaa aagaaactgt agatacagct gatgtggatg ggacacaagc
    39421 aagtccagca gaaactactc ctgaacaagt aaaaggtgga gtgaaagaaa atacaaaaga
    39481 cagcatcgat gttcctgctg cttatcttga aaaagctgaa gggaaaggtc ctttcactgc
    39541 cggtgtaaac caagtaattc cttatgaact attcgctggt gatggtatgt taactcgtct
    39601 attactaaaa gcttcggata atgctccttg gtctgacaat ggtactgcta aaaatcctgc
    39661 tttacctcct cttgaaggat taacaaaagg gaaatacttc tatgaagtag acttaaatgg
    39721 caatactgtt ggtaaacaag gtcaagcttt aattgatcaa cttcgcgcta atggtactca
    39781 aacttataaa gctactgtta aagtttacgg aaataaagac ggtaaagctg acttgactaa
    39841 tctagttgct actaaaaatg tagacatcaa catcaatgga ttagttgcta aagaaactgt
    39901 c
//
LOCUS       DAVLGK010000015        39802 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLGK010000015 DAVLGK010000000
VERSION     DAVLGK010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39802
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.015"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            108..905
                     /locus_tag="VXE01_000876"
     CDS             108..905
                     /locus_tag="VXE01_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV0749820.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGFLMGLPYAFLNKNEDTYVD"
     gene            1053..1175
                     /locus_tag="VXE01_000877"
     CDS             1053..1175
                     /locus_tag="VXE01_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEV0749821.1"
                     /translation="MTCDFKSETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            1197..1718
                     /locus_tag="VXE01_000878"
     CDS             1197..1718
                     /locus_tag="VXE01_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0749822.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFD"
     gene            1719..2312
                     /locus_tag="VXE01_000879"
     CDS             1719..2312
                     /locus_tag="VXE01_000879"
                     /inference="COORDINATES: protein motif:HMM:NF013237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0749823.1"
                     /translation="MTSGKFPQFVDEGSSCHNLSYTRDVGAVAFIIAVRVQLLRDTGA
                     ASSPFNAFLLLQRLETLSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYYALA
                     EKYLPKGVGSIFTFHVKGDEEEARKVIDNLEIFSDLANAADAKSLVVHPATITHGQLS
                     EKDLEAAGVTPNQIHLSIGLENVEDLIEDLRLALEKI"
     gene            2408..3682
                     /locus_tag="VXE01_000880"
     CDS             2408..3682
                     /locus_tag="VXE01_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV0749824.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3692..4570
                     /gene="truB"
                     /locus_tag="VXE01_000881"
     CDS             3692..4570
                     /gene="truB"
                     /locus_tag="VXE01_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV0749825.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4811..5113
                     /locus_tag="VXE01_000882"
     CDS             4811..5113
                     /locus_tag="VXE01_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0749826.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5221..5859
                     /gene="udk"
                     /locus_tag="VXE01_000883"
     CDS             5221..5859
                     /gene="udk"
                     /locus_tag="VXE01_000883"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV0749827.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5987..7327
                     /locus_tag="VXE01_000884"
     CDS             5987..7327
                     /locus_tag="VXE01_000884"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV0749828.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRSTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLDSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7305..7517
                     /locus_tag="VXE01_000885"
     CDS             7305..7517
                     /locus_tag="VXE01_000885"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV0749829.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7514..8389
                     /locus_tag="VXE01_000886"
     CDS             7514..8389
                     /locus_tag="VXE01_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV0749830.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFDEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8382..9197
                     /locus_tag="VXE01_000887"
     CDS             8382..9197
                     /locus_tag="VXE01_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV0749831.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9190..9621
                     /locus_tag="VXE01_000888"
     CDS             9190..9621
                     /locus_tag="VXE01_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0749832.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9628..11295
                     /gene="recN"
                     /locus_tag="VXE01_000889"
     CDS             9628..11295
                     /gene="recN"
                     /locus_tag="VXE01_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV0749833.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11297..12025
                     /locus_tag="VXE01_000890"
     CDS             11297..12025
                     /locus_tag="VXE01_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV0749834.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12104..13927
                     /gene="lepA"
                     /locus_tag="VXE01_000891"
     CDS             12104..13927
                     /gene="lepA"
                     /locus_tag="VXE01_000891"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV0749835.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14131..14211)
                     /locus_tag="VXE01_000892"
                     /pseudo
     CDS             complement(14131..14211)
                     /locus_tag="VXE01_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14385..14861
                     /locus_tag="VXE01_000893"
     CDS             14385..14861
                     /locus_tag="VXE01_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0749836.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            14899..15204
                     /locus_tag="VXE01_000894"
     CDS             14899..15204
                     /locus_tag="VXE01_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0749837.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            15252..16727
                     /locus_tag="VXE01_000895"
     CDS             15252..16727
                     /locus_tag="VXE01_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV0749838.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            16750..16827
                     /locus_tag="VXE01_000896"
                     /pseudo
     CDS             16750..16827
                     /locus_tag="VXE01_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            17032..23730
                     /locus_tag="VXE01_000897"
     CDS             17032..23730
                     /locus_tag="VXE01_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV0749839.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGIYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESDKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSL
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTNLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHTTLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVVVRKGMLELHKPGAVTLNAEYEGATGQITLTIQVNTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKASAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDFVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAGLALLGLSAGLVVTKGKKED"
     gene            complement(23978..24835)
                     /locus_tag="VXE01_000898"
                     /pseudo
     CDS             complement(23978..24835)
                     /locus_tag="VXE01_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(25045..25404)
                     /locus_tag="VXE01_000899"
     CDS             complement(25045..25404)
                     /locus_tag="VXE01_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV0749840.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            25496..26452
                     /locus_tag="VXE01_000900"
                     /pseudo
     CDS             25496..26452
                     /locus_tag="VXE01_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            26436..26993
                     /locus_tag="VXE01_000901"
     CDS             26436..26993
                     /locus_tag="VXE01_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0749841.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            26986..27240
                     /locus_tag="VXE01_000902"
     CDS             26986..27240
                     /locus_tag="VXE01_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749842.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            27252..29306
                     /locus_tag="VXE01_000903"
     CDS             27252..29306
                     /locus_tag="VXE01_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV0749843.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYSRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            29485..30345
                     /locus_tag="VXE01_000904"
     CDS             29485..30345
                     /locus_tag="VXE01_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV0749844.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQILFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            30556..31266
                     /gene="ccdA2"
                     /locus_tag="VXE01_000905"
     CDS             30556..31266
                     /gene="ccdA2"
                     /locus_tag="VXE01_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0749845.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKELYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            31286..31852
                     /locus_tag="VXE01_000906"
     CDS             31286..31852
                     /locus_tag="VXE01_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV0749846.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            31863..32975
                     /gene="msrB"
                     /locus_tag="VXE01_000907"
     CDS             31863..32975
                     /gene="msrB"
                     /locus_tag="VXE01_000907"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0749847.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            33198..33935
                     /locus_tag="VXE01_000908"
     CDS             33198..33935
                     /locus_tag="VXE01_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0749848.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            33932..35623
                     /locus_tag="VXE01_000909"
     CDS             33932..35623
                     /locus_tag="VXE01_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0749849.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VTFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            35739..36302
                     /locus_tag="VXE01_000910"
     CDS             35739..36302
                     /locus_tag="VXE01_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV0749850.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILSSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            36324..>39802
                     /locus_tag="VXE01_000911"
     CDS             36324..>39802
                     /locus_tag="VXE01_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV0749851.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKTEESPKEEPKSEIK
                     PTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEESKVEPP
                     VEQAKGPEQPVQPTQAEQPRIPKDSSQPEDPKEDRGAEETPKQEDTPKQEDTQPEVVE
                     TKDEAANQPVEEPKVETPAVEKQTEPKVEQVGEPVEPSEDEKAPVSPEKQPEAPEEKA
                     VEETPKPEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNDLGPVLETAKGV
                     YASEPVKQPEVNSETNKLKTAIDALNVDKSELQEQLRVAEQKQQADYSAKTWREFKIA
                     ELQAKEINNQTTPLPKQSEIDAATKALQDALQALAVDKTVLQNAINTANSKREEEYTA
                     QTWKALEDALTAVNPVNEDETATQSKVDEATRNLEEAINNLVLLTEKPVLTFIETDKK
                     ALEREVVAKYSLENQNKTKIKSITATLKKGETVVSTVELIGDDVTNETITSAFKNLEY
                     YKEYTLSTTMVYDRGDGDVTEILDNQPIQLDLKKVELKNIKRTDLIKYENGKETNESL
                     ITTVPDDKRNYYLKITSKNQKTTLLAVKNIEETTVNGTPVYKVTAIADNLVSRTADNK
                     FEEEYVHYIEKPKVHEDNVYYNFKELVEAIQNDPSKEYRLGQSMSARNVVPNGKSYIT
                     KEFTGKLLSSEGKQFAITELEHPLFNVITNATINNVNFENVEIERSGQDNIASLANTM
                     KGSSVITNVKITGTLSGRNNVAGFVNNMNDGTRIENVAFFGKLHSTSGNGSHTGGIAG
                     TNYRGIVRKAYVDATITGNKTRASLLVPKVDYGLTLDHLIGTKALLTESVVKGKIDVS
                     NPVEVGAIASKTWPVGTVSNSVSYAKIIRGEELFGSNDVDDSDYASAHIKDLYAVEGY
                     SSGNRSFRKSKTFTKLTKEQADAKVTTFNITADKLESDLSPLAKLNEEKAYSSIQDYN
                     AEYNQAYKNLEKL"
BASE COUNT        12195 a         7367 c         8934 g        11306 t
ORIGIN      
        1 ctattctagt ttcaatctac tataaacttt tatgaaatac agaaaacgct tcctaaaacc
       61 taaagtttgt gatataatta tcaagaaaaa agatttagga gtttattatg gtttcttcag
      121 aatttatttc aaagattgaa tttgcttgca ataagaaaga aagtctttat agtcaaagca
      181 aatttaagta tgcgattcgt tcgatgttcg caggtgcatt tttaaccttc agtactgctg
      241 caggtgcagt tggggctgac ttgattaata aaattgcacc aggtagtgga cgcttcctct
      301 ttccattcgt ttttgcttgg ggcttggcct acattgtttt tttgaatgcc gagttggtca
      361 cttcaaacat gatgttcttg actgctggta gtttcttaaa aaaaatctct tggagaaaaa
      421 cagctgagat tttactatac tgtaccttgt tcaaccttat cggagccttg atagcagggt
      481 ggggctttgc tcattcggca gcctatgcga atctgacaca cgatagtttc atctcaggtg
      541 ttgttgagat gaagttaggc cgctcaaatg aattggtctt gcttgaggcg attttggcaa
      601 atattttcgt aaatattgcg attctgtcat ttattttggt caaagatggt ggtgccaaac
      661 tttggcttgt gttgtcagct atttacatgt ttgtattctt aacaaacgag cacattgcgg
      721 cgaactttgc ttctttcgcg attgtgaaat tcagtgttgc tgcggattca attgccaact
      781 tcggtgttgg aaatatgctt cgccactggg gtgtgacttt catcggaaac tttatcggag
      841 gaggcttctt gatgggtctt ccatatgcct tcctcaataa aaacgaagat acttatgtag
      901 attaagaaaa tgagcacgat tgagtcgtgc ttttttcatt ttcaaaataa ggtaatagct
      961 atttcttata tcaaaatata gaaaactgat atttgtaaac tataactcaa ggtgctacaa
     1021 tatccttaat aaaatgatat ggaggtcacc ttatgacttg tgattttaaa tctgaaactc
     1081 tacaactaca tgctggtcaa gttgtggctc cagctactaa gtctcgtgca gtgccgattt
     1141 atcaaacaac attttttgtt tttgatgaca cgtaggaagg tgccgatctg tttgccttga
     1201 ggaaaccagg gaacatttat actcgtatca ccaatcctac aacagctgcc cttgaaggtg
     1261 gtgttgaagc gctagcaaca gcatcaggta tgactgcagt gacttatacg attttggcgc
     1321 ttgcccatgc tggtgaccat gtagtggctg cttcgactat ttacggtgga accttcaatc
     1381 ttttgaaaga accccttcct cgttatggta tcacaacaac ctttgtcgat gttgataatt
     1441 tggaggaagt agaagcagct atcaaagaca ataccaagct tgtcttgatt gaaaccttgg
     1501 gtaactcctt gattaatatt ccagacctgg aaaaactggc agagattgct cataaacatc
     1561 aaatcccact tgtgtcagac aatacttttg caatacctta tttgattaac gtcttctctc
     1621 atggcgttga cattgccatt cactctgcga ctaagtttat cggtgggcat ggtacaacta
     1681 ttggaggaat aattgtcgat agtggtcgtt ttgactgaat gacttcaggg aaattccctc
     1741 aatttgttga cgagggttca agctgccaca atttgagcta tactcgtgat gtgggtgcag
     1801 tagcctttat tatagctgtt cgagttcaat tgcttcgtga tacaggtgca gcctcgtcac
     1861 cattcaatgc tttcctcttg ctacaaagac ttgaaaccct ttcacttcgt gtggaacgcc
     1921 atgtacaaaa tgctgagaca attgttgatt ttcttgtcaa ccatcctaag gtagaaaagg
     1981 taaattatcc aaaacttgca gatagtcctt attatgcctt ggctgagaaa tacttgccaa
     2041 aaggtgtcgg ttcaatcttt accttccacg tcaaaggtga cgaggaagaa gcacgcaagg
     2101 tcattgataa tttagaaatc ttttctgacc ttgcaaacgc ggcagatgct aaatcgcttg
     2161 ttgtccatcc agcaacaatc actcacggtc aattgtcaga aaaagaccta gaagcagcag
     2221 gtgtcacacc aaatcaaatc cacttgtcta tcggtcttga aaatgtagaa gatttgattg
     2281 aagacttacg cttggccttg gaaaaaattt aaagtaaaag aagataaaca gtgggttttg
     2341 actcactgtt tttgattttc cctcaggcat gatataatgg ttacagaagt ctagaaagag
     2401 gaatgtaatg aacgaaatca aatgtcccaa ctgtggggaa gtctttacag taaatgaaag
     2461 ccagtatgct gaacttttgt cccaagtgag aacggcagag tttgataagg aactacacga
     2521 taggatgagg caggaactgg ccttggctga gcaaaaggct atgaatgagc aacagactaa
     2581 actggctcag aaggatcaag aaattgcgca attgcagagt caaatccaaa actttgatac
     2641 agaaaaagaa ttggccaaga aagaagttga acagacaagc catcaggcct tattggctaa
     2701 ggacaaggaa gtacaggcct tggaaaacca gttggcgacc ttgcgtttgg agcatgaaaa
     2761 tcaactgcaa aagacccttt ctgacctaga aaaagaacgc aatcaggtca aaaatcagct
     2821 cctactgcaa gaaaaggaaa atgagttgtc tttggcttct gttaagcaaa actacgaagc
     2881 ccagctcaaa gcagccagtg aacaagtcga gttttataag aattttaagg ctcaacaatc
     2941 tacaaaagcg attggggaaa gcctagaaca gtatgcagag agtgagttta acaaggttcg
     3001 tagtttcgcc tttccaaatg cttactttga gaaggataac aaggtctctt cgcgtgggtc
     3061 taaaggggac tttatcttcc gtgagtgtga tgaaaatgga gttgaaatca tttctatcat
     3121 gtttgagatg aaaaacgaag cggacggaac agagaagaag cacaagaatg cagattttta
     3181 caaggaattg gacaaggacc gtcgggagaa gaactgtgag tatgccgttt tggtgaccat
     3241 gcttgaggct gataatgact actttaacac agggattgtt gacgtcagtc acgagtatga
     3301 aaaaatgtat gttgttcgtc ctcaattctt tatccaattg attggtctct tacgtaatgc
     3361 ggcgctaaat tccctaaaat acaagcagga gttggccttg gttcgcgagc aaaatattga
     3421 cattacgcat tttgaggaag atttggatgc ctttaagcta gcttttgcta agaactataa
     3481 ttcagcttcg actaactttg gaaaagctat tgatgaaatc gacaaggcca tcaaacgcat
     3541 ggaagaggtt aagaaattcc tgactacatc tgaaaaccaa ctccgtctag ctaacaacaa
     3601 attggaagat gtctctgtta aaaaattgac ccggaaaaat ccaacaatga aagcgaagtt
     3661 cgaagcactg aagggggagt agaaagcaaa aatgaacggt attatcaact taaaaaaaga
     3721 agcaggaatg acctcgcatg atgcggtttt taaactgcgt aagattttgg gaaccaagaa
     3781 aattggtcat ggcggaacct tggatccgga tgtggtgggt gttttgccga ttgcggttgg
     3841 caaggcgaca cgcatggtcg agtttatgca ggacgagggt aagatctatg agggggaaat
     3901 cactctgggc tattccacga cgactgagga tgctagtggg gaagtggtcg cagaaacccc
     3961 tgttttgtct cccttggatg aaaagcttgt tgatgaagcg attgctagct tgactgggcc
     4021 tattactcag attcccccta tgtattcggc agttaaggtt aatggtcgca agctctatga
     4081 gtatgcgcgt gctggtcagg aagtggagcg tccagaacgt caggtgacca tttatcaatt
     4141 tgagcgaaca agtccgattt cttatgatgg ccaacttgcc cgattcactt ttcgtgtaaa
     4201 atgcagtaaa gggacttaca tccgtacttt gtcagttgat ttgggtgaaa agcttggtta
     4261 tgcggctcat atgtcccatt tgactcgtac tagtgctgct ggcttacaat tagaagatgc
     4321 tcttaccttg gaggaaattg ctgaaaaagt agaggctggg caattagatt ttctccatcc
     4381 tttagagatt gggacaggtg accttgtcaa agttttccta actccagaag aggctacaga
     4441 agttcgcttt ggtcgtttta ttgagctaga ccaaacggac aaagaactgg ctgcctttga
     4501 agatgataaa ttattagcca ttctagaaaa acggggcaat ctctataagc caaggaaggt
     4561 ttttagctag atcgtttagg aataaaaatc gggtgataga taacaattgc ttgataaaac
     4621 cccatactaa tagtagaatg gttttgggaa ttataatatt ccaattgttg cgagttgtag
     4681 gtactcaaat aatctatata gaaatttaga ggtgtgaaat gaagcaattt aaaattcttt
     4741 cagataaata tttagagtcc attacaggtt ctggtgggaa cttaggccca ggatttggtg
     4801 tgataattcc atgatgcgaa atgagtttcg agaaagggtg gagcaacttc ttcaacaaaa
     4861 agaaataaat gaaaatagtg agttgagtca cctgtttcgt cttgctatac aaaatttaga
     4921 cagaaatgaa aaataccaaa cggtcatggc caatttgagt caagggttgt cactttacct
     4981 catgacgcat cattaccagg cacctaagtc tgtcattgat tttggtttat ggattgccaa
     5041 agctcctagc caggaaagag ggagactggc tttcttgcag atgcttgctc aaaccctaca
     5101 gggctttcgt taaaactgtc gaacatcaga gggaagactc tggtgttttt tgctgatgag
     5161 actataaatt ttgtaaaaaa tgtgatagaa tagacgacgg ataaaataac ggaggatagc
     5221 atgcaaaata gaccaatcat tattggagtg acaggtggtt ctggtggtgg taaaaccagt
     5281 gtttcaagag ccattttatc gcattttcct gatgaaaaga tttccatgat tgagcatgat
     5341 tcatactaca aggatcagtc tcatttgacc tttgaagagc gtgtcaaaac caactatgac
     5401 catccttttg cctttgatac agacttgatg atcgagcaga ttaaggaatt gttggcaggg
     5461 cgtccggtgg acatcccgac ctacgactat acagagcata cacggagtag caagacctat
     5521 cgtcaggagc ctcaagatgt ctttatcgtt gagggcattt tggtcttgga ggacaagcgt
     5581 ctgcgcgatt tgatggatat caagattttt gtggatacgg atgacgatgt gcgtattatt
     5641 cgtcgtatca agcgtgatat ggaggaacgt ggccgtagcc ttgatagcgt tattaaccag
     5701 tacttaggtg tggtcaaacc aatgtaccac cagtttatcg agtcaactaa gcgttatgct
     5761 gatatcgtca ttcctgaagg ggttagcaat accgtggcta tcgacctgtt gacgaccaag
     5821 attgcaaaga ttttggaaga agctcgaaac agcaaataat cacatgtgga ggccttgcct
     5881 cctttttcta tttttccctc ataatggtac ataaatggag atttttaggc atatttttgg
     5941 tataataata cccataaaag agcaagtaaa tgaatagtag gtggagatgg aaaagtattt
     6001 atcggtaaca actttgacca agtatctgaa aatgaaattc gataaagacc catacttgga
     6061 acgggtctat ttaactggtc aagtttccaa ctttcgtaaa cgatctactc accaatattt
     6121 ctccctaaag gatgaccatg cagttattca agcgaccatc tggtctggga tttatcagaa
     6181 attagggttt gacctggaag aaggaatgaa gatcaatgtg attgggcgtg tacaggtcta
     6241 tgaaccaagt ggtagctact ccatcatcat tgaaaaagct gagcctgatg gggttggggc
     6301 gcttgcgatt cagtttgaac aacttaagaa aaaattgaca gaagaaggcc tgtttcaaga
     6361 acgcttcaag caagctctac cccaattttc taagagaatt ggggtagtaa ccagccgtag
     6421 tggagccgtt attcgagata ttatcacgac cgtcagcagg cgattcccag gtgttgacat
     6481 ccttctttat ccgaccaagg ttcaaggtga aggggctgcg gaggaaattg ctagaaatat
     6541 tgcgcgtgct aatcaacggg acgatttgga tttgctcatt attggtcgtg gaggtggttc
     6601 tattgaggat ctctgggcct ttaacgaaga aattgtggta cgagctattt ttgaatctcg
     6661 tttgccagtt atctctagtg tggggcatga gacggatgtg accttggcag attttgtggc
     6721 agatcgacgc gctgcaacgc caacagcggc ggctgaactg gcaacacctg tgaccaagtt
     6781 ggatgtatta actcatttgc aaaatcagga aaaacggatg gcaacggcag tccgaaatgt
     6841 tctatctaag aaacaagagg ctttgaaaaa atgcagtcag tctgttatct ttagacaacc
     6901 tgagcgcttg tatgacggtt atttgcaacg cttggaccaa ctgcaactgc gtttgaaaca
     6961 aagtttgcga actcggattt ctgataacaa acaattagtt caagcaagaa ctcatcaatt
     7021 agtacaatta tcacctgtta ccaaaatcca acgctatcaa gaccgtttag gacagttgga
     7081 caagctctta gatagccaaa tggcgttagt ttatgacgcc aaggttgctg aggccaagcg
     7141 actttcggaa gctttgctca tgttggatac tagccgaatc gtggcgcgtg gttatgctat
     7201 tgtcaaaaaa gaagagtcca ttgtagattc ggttgagagt ttgaagaaaa aagaccaagt
     7261 aacgcttttg atgcgagatg gtcaagtaga attagaggtt aaagatgtca aaacaaaaga
     7321 aatttgagga aaatctagca gaactggaaa ccattgtcca aagtttggaa aatggtgaaa
     7381 ttgctctgga agatgcgatt actgcctttc aaaagggcat ggtcttgtca aaagagctcc
     7441 aagctacgct ggacaaggct gaaaagacct tggtcaaggt catgcaagaa gacggaacag
     7501 aaagtgattt tgaatgaaaa agcaagaaaa attagctctt gtcgagtcgg ctttggaaga
     7561 tttttatgga gaccagcagt ttgcctctag tttacgggag tctgttctct attctattca
     7621 tgctggtggc aagcgtattc ggccttttct cttgttagaa gttctggaat ccttgcaggt
     7681 taccatcaaa cctgctcacg cgcaggtagc tactgccttg gagatgattc atacagggag
     7741 cttgattcac gatgaccttc ctgctatgga tgatgacgat tatcgaagag ggcggttaac
     7801 caatcacaag aaattcggtg aagctatggc cattttggct ggagatgcct tattcttaga
     7861 cccatatgcc ttgattgcgc aggcagattt gccaagtcag atcaaggtgg acttgattgc
     7921 caacttatcc cttgcttcag gtagtctggg tatggtggca gggcaagttt tggatatgga
     7981 gggcgaacac cagcacttgt ctctggaaga acttcagact attcatgcca ataagactgg
     8041 gaagttacta gcctatccct tccaagcggc agctattata gctgaattgt cacctgaaat
     8101 gcaggtgaag ctgaaaactg tgggtgaatt gattggactt gcttttcaag tcagagatga
     8161 tgtactggat gtgacagcta gttttgatga aatcggcaag acacctcaaa aggatctgca
     8221 ggcagaaaaa tcaacctatc ctgccttgtt gggcttggaa gagtccattg ccttttgtaa
     8281 ccaaaccctg gatcaagcta atgaaaaatt agaagaaatt gcccagcagc ttccctttga
     8341 aacagaatcg attgtaagtg tagtagaaag tttgagaatc aatggctaag gaaagagtgg
     8401 atgtactagc ttataaacag gggttgtttg aaacgagaga gcaggccaag cgaggtgtga
     8461 tggctggcct agtcgtagca gtccttaatg gagaacggtt tgacaagcca ggagagaaaa
     8521 ttccagatga caccgaatta aaactcaagg gggagaaact caagtatgtc agccgtggtg
     8581 gtttgaaact ggaaaaggcc ttgcaggtct ttgatttgtc ggtggatggc gcgactacga
     8641 ttgatatcgg ggcctctact ggaggtttta ccgatgtcat gctacagaat agtgccaagt
     8701 tggtctttgc agtcgatgtt ggtaccaatc agttggcttg gaaattacgc caagacccac
     8761 gagttgtcag catggagcag ttcaattttc gctatgctga aaagactgat ttcgagcagg
     8821 agccgagctt tgccagtatt gatgtgagtt tcatttccct tagtctgatt ttgccagcct
     8881 tgcaccgtgt cttggctgat caaggtcagg tggtagcact tgtcaaacct cagtttgagg
     8941 caggacgtga gcagattggg aaaaatggaa ttattcgaga tgctaagatt catcagaatg
     9001 tccttgaatc tgtaacagct atggcagtag aggcaggttt ttcagtcctt ggcttggact
     9061 tttctcccat ccaaggtgga catggaaata ttgaattttt agcgtatttg aaaaaagaaa
     9121 agtcagcaag caatcagatt cttgctgaga ttaaagaagc agtagagagg gcgcatagtc
     9181 aatttaaaaa tgaataaaaa agaaagactt gaaaaaatta gaagattggt gacagattat
     9241 caaatcggca cgcaagaaga aattgtagaa catttgaaag aagcaggtat cactgccact
     9301 caggcgacgg tatcccgaga tatcaaagag ttaggtattg tcaaaattcc tttgagagac
     9361 aacacctatg tctacgaatt accaaaatca atcgtaaaaa gtctgcaact ggctgaagac
     9421 aatatcgaat cggctgaatt gatggataag atgatcaatc tccaagttat tccaggaaat
     9481 acggcttttg taaaagctca gttaatcgat acttttgcag acaagatttt tagctgtttg
     9541 actgatgata gctcgatttt agtcattgcc agaagtggaa gtctagcaga ggaaatcttt
     9601 gaacaagtaa aaaattggta ggtctatatg ttacttgaaa tttcgataaa aaactttgcc
     9661 attattgaag ctatttccct caattttgaa aaggggatga ctgtcctgac tggtgaaacg
     9721 ggtgcaggga agtcgattat cattgatgcc atgaatatga tgttgggagc tcgtgcgacg
     9781 acagatgtta ttcgtcatgg tgcaccaaag gcagagattg aggggctttt ctcagttgag
     9841 aatagtcgtc ttttacagga aatttttgat gagcaaggtt tagaattagg tgatgaaatt
     9901 atcatccgtc gggaaatctt gcaaaatggt cgtagtatca gccgtgtaaa tggtcagatg
     9961 gttaatctgt ctgttttgcg agctattggg caacatcttg tagatattca tggtcagcat
    10021 gaccatgagg agttaatgcg tccccaactg catatccaga tgttggatga atttggtgat
    10081 gccgcttttt gggacttgaa agaaacctat caaacgagtt ttgatgccta tcggaaaatg
    10141 cgcaagcagg ttctggaagt caagaaaaac caacaggaac acaaggcacg tatcgaaatg
    10201 ttggaatttc aaatggcaga gattgaggca gcaaacttgc aggctggaga agacttggct
    10261 ctcaatcaag agcgagataa actcctcaac cacaaaaata ttgcggatac actgaccaat
    10321 gcctacagta tgttggacaa tgaagatttt tcaagtctgg ccaatgttcg ttcagctatg
    10381 aatgacatgg aaagtgtcga agagtatgat cctgaatacc gtgaaatttc aagctctctg
    10441 tctgagacct actatgtttt agaagacatt agcaaacgtt tggaagctat cattgaggac
    10501 cttgattttg atggcaatcg cctcatgcag gttgagaatc gtttggacct ccttcatact
    10561 attactcgta agtatggtgg gactgttgat gatgttttgc tttattttgc caagattacg
    10621 gaagaataca atctcttgac aggcaataat ctttcgtctg aggacatgga agcagagctt
    10681 aagaagttgg aagtcaatct tgtcaatttg gcaggtcaac ttgcttctgc tcgtcataat
    10741 ttggctcagc aactcgaagc tgagattaaa caagaactgc aagatcttta tatggaaaaa
    10801 gcccagtttc aggttcgttt tagtaaggga aaattcagtc gtgggggaaa tgaaatggtt
    10861 gaattttata tttcaaccaa ccctggagaa gactttaaac ccttggttaa ggttgcttct
    10921 ggaggggaat tatctcgtct catgttagcc attaagtctg ccttttcacg taaagaaggc
    10981 aagactagca ttgtctttga tgaggtggat acgggagttt caggtcgtgt tgctcaagct
    11041 attgctcaga aaattcataa aattggtcag tatggtcagg ttttggctat ctcccatttg
    11101 ccacaagtaa ttgcgattgc agattatcaa ttctttattg agaagattag taatgaccat
    11161 tcaacggttt cgactgttcg tctcttgaca gtcgaagagc gagtggagga agttgccaag
    11221 atgttggcag gtgatgatgt gacagaagca gccctgacgc aagccagaga attgttgaga
    11281 aacagggaga aataagatga cagattatta tgtaattgga gatgttcacg gaaaagctgg
    11341 gatgctggaa gaccttctta aaacctggga tggtcagacc cagttgctct ttctaggtga
    11401 tttgattgac agaggtgagg atagtcaccg tgttcttgaa atggtcaagg acttggtgga
    11461 caatcaaggg gctatctgtt tgtctggaaa ccacgagtat atgtttttga cttggctaga
    11521 tgacccagaa gaaagttatg accattatcg tcgcaatggt ggagatacaa ccattaactc
    11581 tatcctaggt cgtcccttgg atgcaccagt tgatggagta gaagatgcca agcgggttgc
    11641 cgctgaagcg gcagacttgg tcgaattcat tcgtcaaatg ccatttgtag tagagacaga
    11701 caagtatatc tttgttcacg caggtattga tttgaccttg gacgactggc atgaaacaac
    11761 agattataaa aaagtatggc ttagaaaacc attccacgga gctgaaaatc atactggaaa
    11821 aaccattgtc ttcggtcata caccggtcta tggtttgtta cagcaagaac gcggtacatc
    11881 tgagctttgg actacagaag atggcaagat tggaatggat ggaggagctg tttatggtgg
    11941 tgtccttcac gggattgtct ttacagacca aggaatgaca gaacaccact ttatcgaaaa
    12001 tgacggcttt gtcgctgaag attagtactc ctagcagggt atggtcttgt caaaatatca
    12061 aaaacaattt ataataaata gataccctga aaggaagaga atcatgaact tagaagaatt
    12121 gaaaaaacga caggagaaga tccgtaactt ctctattatc gcccatattg accatggaaa
    12181 atcaactcta gcagaccgca ttttggaaaa aacagagacg gtttcaagtc gtgaaatgca
    12241 ggcccagctt ttggatagca tggagctaga gcgggaacgt ggaattacta ttaagttgaa
    12301 tgccatcgag ttgaattaca ctgcaaaaga tggggaaact tatattttcc atttgattga
    12361 cacaccaggg cacgttgact ttacctatga agtttcacgt tcgctagctg cctgtgaggg
    12421 tgctattttg gtggtcgatg cggctcaagg aattgaggct caaactcttg ccaacgttta
    12481 tctggctttg gataatgatt tggaaatcat gcctatcatt aataaaattg acctgccggc
    12541 tgcagatccg gagcgcgtgc gtacagagat tgaagatgtg attggtttgg atgccagtga
    12601 agcagttttg gcttctgcca aggctggtat tgggattgaa gaaatcctcg agcaaattgt
    12661 agaaaaagta ccagcaccaa cgggtgatgt gacggcgcca cttaaggcct tgattttcga
    12721 ctctgtttac gatgcttacc gtggggttat cctccaagtg cgtgtcatgg acggagtggt
    12781 caaacctggt gataagattc agctcatgag caatagtaag acctttgatg tggccgaagt
    12841 cggtattttt acaccaaaag cggttggtcg tgatttcctt gcgactggtg atgttggtta
    12901 cattgcggcg tctatcaaga cggttcagga tactcgtgtg ggtgataccg ttaccttggc
    12961 aaccaatcct gcggcagaac cattacatgg ttataagcag atgaatccta tggtctttgc
    13021 gggtctctac ccaatcgaat caaacaaata caatgacctg cgtgaagcgc ttgaaaaatt
    13081 gcaactgaat gatgctagtc ttcagtttga accagaaaca tctcaggcac ttggatttgg
    13141 tttccgttgt ggatttcttg gacttctcca tatggatgtt atccaggaac gtttagagcg
    13201 tgagttcaat attgacctca tcatgacagc tccgtctgtt atttacaaag ttaatttgac
    13261 cgacggtgag tctatggatg tgtctaaccc atctgagttt ccagacccaa ctaagattgc
    13321 gaccattgaa gagccttatg tcaaggcgca aatcatggta ccacaggagt tcgtcggagc
    13381 agtaatggag ctagctcagc gtaagcgtgg ggactttgtg actatggact atattgatga
    13441 taaccgtgtc aatgttatct atcaaattcc tcttgctgaa attgtctttg acttctttga
    13501 taaacttaag tcttcgacac gtggttatgc aagctttgac tacgaattgt cagaatatcg
    13561 cccatctaag ctggtgaaaa tggatatcct tctcaatgga gataaggtgg atgccctcag
    13621 ctttatcgtt cacaaggact ttgcctacga acgtgggaaa ctcatcgttg ataaactcaa
    13681 gaaaatcatc cctcgccaac aatttgaagt tccaatccaa gcggctattg gacacaagat
    13741 tgtcgctcgt actgatatca aggcccttcg taagaacgta cttgctaaat gttatggtgg
    13801 tgacgtttct cgtaagcgta aactccttga aaaacaaaaa gctggtaaga aacgcatgaa
    13861 atccatcgga tcagttgaag ttccgcaaga agccttcctc agcgtcttga gtatggatga
    13921 agaataagtt atcagaaatg cctttccttg ttcacaggaa atttatataa gaatcaatag
    13981 taaagcaggc ttagatggtc tgctttttta gtttttatac tcttcgaaaa tctcttcaaa
    14041 ccacgtcagc gtcgccttac cgtatgtatg gttactgact tcgtcagttt catctacaac
    14101 ctcaaaatca tgttttgagc tgacttcgtc agtttcatct acaacctcaa aactgtgttt
    14161 tgagtaacct gcggctagct tcctagtttg ctctttgatt ttcattgagt attagaacag
    14221 aaaaatgctt ggagtatttg tttgtgtgtt tatttttata taacaaacta taaacaaaac
    14281 aaaaatataa aaaaagagac aaaaaagaac aaaaagtaat tgacaacggt ttcatatagt
    14341 gttatactta tggcataaag ttaatggaaa gaagggaaaa acttatggta ttagattatt
    14401 tctttgacaa aaaccttgtg ttttgcttag aagcggataa tcaagaacat ctctttgatc
    14461 aggttgcaac tttattggaa gaacgagaaa ttgtaactcc aacttatcgt gaagccttga
    14521 tcacgcgtga aaagtcattt ccaactggtt tagatatgga atttctagga aaggacttgc
    14581 caaatgtagc gattcctcac acagatattg ttcataatct agctgagaaa gtggtggttg
    14641 ttcgattaga aaaaccagta acttttcaca atatgatagc tcctgataag gaagtagaag
    14701 tatctctact cttctttatc attaacaatt caagttcaag tcaaacgaac attctggctc
    14761 agttgatgga ctttttcaca ggaaatggtc atcttgaaga cctatcaaaa atttctgaac
    14821 cagaaaaact ttatgcttac attgctgaag caaccgctta atcttgtcta ttaaaaaata
    14881 aaatcggagg aaatccaaat gattaaaatt cttgctgcct gcggtgcagg tgttaactca
    14941 agtcaccaaa ttaaaagtgc tctagaagaa gaactttcaa accgtggtta tgatgttcac
    15001 tgtgatgcag tcatggtgaa agatgtaaac gaagacctta tgaaaggtta cgatatcttt
    15061 acaccaatcg ctgcaacaga ccttggtttt gaaccaggta tcccagttat cgaagctggg
    15121 ccaatcttat tccgtatccc agcaatgagc gctccagtat ttgacaatat tgaagcagct
    15181 attaaagaac atggattaag ctaattctaa tttgttaaca ttcatataac ataaaaaagg
    15241 gaggaactgt tatggatgca atctttgacc taatcggaaa ggttttcaat cccatcttag
    15301 aaatgggtgg acctgtcatc atgttgatca ttttgacagt attggcttta ctttttggag
    15361 tgaaattctc caaagcgctt gaaggtggta tcaaacttgc catcgctctt acaggtatcg
    15421 gtgctatcat cggtatgcta aatggtgctt tctcagcatc acttgcaaaa ttcgttgaaa
    15481 acactggtat ccaattgagt attacagacg ttggttgggc accactcgca acaatcactt
    15541 ggggttctgc ttggacacta tacttcttgc tcatcatgtt gattgtcaac gtagtgatgc
    15601 ttgctatgaa gaaaaccgat acacttgatg tcgatatctt tgatatctgg cacttgtcta
    15661 tcacaggtct cttgattaaa tggtatgctg ataacaatgg tgtgagtcaa ggggtttcac
    15721 tctttattgc tacagcagct atcgtccttg tcggtgtgtt gaaaattatc aactctgact
    15781 tgatgaaacc tacatttgat gaccttctta acgccccaag ttcatcacca atgacatcaa
    15841 ctcacatgaa ctacatgatg aacccagtta tcatggtttt ggataagatt tttgaaaaat
    15901 tcttcccagg ccttgataaa tatgactttg atgctgctaa attgaacaag aaaatcggtt
    15961 tctggggatc taaattcttc atcggtttca tccttggtat cgttatcggt attatgggaa
    16021 ctccacatcc aattgcaggt gttgcagatg cagataaatg gcgtcttgtt atcaaaggat
    16081 ggttgtctct tggtttgact gccggtgtat ctttggaact cttctcactt atcggttcat
    16141 ggttcatcgc agccgtagaa ccactatcac aaggtattac aaacgttgct actaaacgtc
    16201 ttcaaggacg taaattcaat atcggtcttg actggccatt catcgctggt cgtgctgaaa
    16261 tctgggcttg tgccaacgta cttgcaccaa tcatgttgat tgaagcagtg cttctttcaa
    16321 aagttggaaa tggtatcttg ccacttgcag gtatcatcgc tatgggtgtt actccagctc
    16381 tcttggttgt aactcgtggt aaattgctcc gtatgattat cttcggaaca ctcttgttgc
    16441 cactcttcct tctttcaggt acccttattg caccatttgc aacagaactt gctaaaggtg
    16501 taggtgcctt cccagaaggt gtgagccaaa ctcaattgat tactcactct actcttgaag
    16561 gaccaatcga aaaacttctt ggttggacaa ttggtaacac tacaactggt gatatcaaag
    16621 caatccttgg tgcagtagtc ttccttgtat tctatatcgg tatctttgct tggtacagaa
    16681 aacaaatgat caaacgtaac gaagagtacg cagcaaaagc aaaataatgc gctcctataa
    16741 aatataaact caatgaaaat caaagagcaa actaggaaac tagccacagg ttgctcaaaa
    16801 cacagttttg aggttgtaga taagactggc gaagtcagct caaaacatgg ttttgaggtt
    16861 atagatgaaa ctgacgaagt cagtaatcat acatacggca aggcgacact gacgaagttt
    16921 gaattggatt ttcgcagagt gtaaattgtt gaaactaggt tgtcatacca tgtataccac
    16981 ttgggctttg gtagtagcta actgcactaa atataatata aggagggttt tatggggaaa
    17041 ggccattgga atcggaaaag agtttatagc attcgtaagt ttgctgtggg agcttgctca
    17101 gtaatgattg ggacttgtgc agttctatta ggaggaaata tagctggaga atctgtagtt
    17161 tatgcggatg aaacacttat tactcatact gctgagaaac ctaaagagga aaaaatgata
    17221 gtagaagaaa aggctgataa agctttggaa actaaaaatg tagttgaaag gacagaacaa
    17281 agtgaaccta gttcaactga ggctattgca tctgagaaga aagaagatga agccgtaact
    17341 ccaaaagagg aaaaagtgtc tgctaaaccg gaagaaaaag ctccaaggat agaatcacaa
    17401 gcttcaaatc aagaaaaacc gctcaaggaa gatgctaaag ctgtaacaaa tgaagaagtg
    17461 aatcaaatga ttgaagacag gaaagtggat tttaatcaaa attggtattt taaactcaat
    17521 gcaaattcta aggaagccat taaacctgat gcagacgtat ctacgtggaa aaaattagat
    17581 ttaccgtatg actggagtat ctttaacgat ttcgatcatg aatctcctgc acaaaatgaa
    17641 ggtggacagc tcaacggtgg ggaagcttgg tatcgcaaga ctttcaaact agatgaaaaa
    17701 gacctcaaga aaaatgttcg ccttactttt gatggcgtct acatggattc tcaagtttat
    17761 gtcaatggtc agttagtggg gcattatcca aatggttata accagttctc atacgatatc
    17821 accaaatacc ttcacaaaga tggtcgtgag aatgtgattg ctgtccatgc agtcaacaaa
    17881 cagccaagta gccgttggta ttcaggaagt ggtatctatc gtgatgtgac tttacaagtg
    17941 acagataagg tgcatgttga gaaaaatggg acaactattt taacaccaaa acttgaagaa
    18001 caacaacatg gcaaggttga aactcatgtg accagcaaaa tcgtcaatac ggacgacaaa
    18061 gaccatgaac ttgtagccga atatcaaatc gttgaacgag gtggtcatgc tgtaacaggc
    18121 ttagttcgta cagcgagtcg taccttaaaa gcacatgaat caacaagcct agatgcgatt
    18181 ttagaagttg aaagaccaaa actctggacc gttttaaatg acaaacctgc cttgtacgaa
    18241 ttgattacgc gtgtttaccg tgacggtcaa ttggttgatg ctaagaagga tttgtttggt
    18301 taccgttact atcactggac tccaaatgaa ggtttctctt tgaatggtga acgtattaaa
    18361 ttccatggag tatccttgca ccacgaccat ggggcgcttg gagcagaaga aaattataaa
    18421 gcagaatatc gccgtctcaa acaaatgaag gagatgggag ttaactccat ccgtacaacc
    18481 cacaaccctg ctagtgagca aaccttgcaa atcgcagcag aactaggttt actcgttcag
    18541 gaagaggctt ttgatacttg gtatggtggc aagaaacctt atgactatgg acgttttttt
    18601 gaaaaagatg ccactcaccc agaagctcga aaaggtgaaa aatggtctga ttttgaccta
    18661 cgtaccatgg tcgaaagagg caaaaacaac cctgctatct tcatgtggtc aattggtaat
    18721 gaaataggtg aagctaatgg tgatgcccac tctttagcaa ctgttaaacg tttggtcaag
    18781 gttatcaagg atgttgataa gactcgctat gttaccatgg gagcagataa attccgtttc
    18841 ggtaatggta gcggagggca tgagaaaatt gctgatgaac tcgatgctgt tggatttaac
    18901 tattctgaag ataattacaa agcccttaga gctaagcatc caaaatggtt gatttatgga
    18961 tcagaaacat cttcagctac ccgtacacgt ggaatttact atcgccctga acgtgaattg
    19021 aaacatagca atggacctga gcgtaattat gaacagtctg actatgggaa tgatcgtgtt
    19081 ggttggggga aaacagcaac cgcttcatgg acttttgacc gtgacaacgc tggctatgct
    19141 ggacagttta tctggacagg tacggactat attggtgaac ctacaccatg gcataaccaa
    19201 aatcaaactc ctgttaagag ctcttacttt ggtatcgtag atacagccgg cattccaaaa
    19261 catgacttct acctctacca aagccaatgg gtttctgtta aaaagaaacc gatggtacac
    19321 cttcttcctc actggaactg ggaaaacaaa gaattagcat ccaaagtagc tgactcagaa
    19381 ggtaagattc cagttcgtgc ttattcgaat gcttctagtg tagaattatt cttgaatgga
    19441 aaatctcttg gtcttaagac tttcaataaa aaacaaacca gcgatgggcg gacttaccaa
    19501 gaaggtgcaa atgctaatga actttatctt gaatggaaag ttgcctatca accgggtacc
    19561 ttggaagcaa ttgctcgtga tgaatctgac aaggaaattg ctcgagataa gattacgact
    19621 gctggtaagc cagcggcagt tcgtcttatt aaggaagacc atgcgattgc agcagatgga
    19681 aaagacttga cttacatcta ctatgaaatt gttgacagcc aggggaatgt ggttccaact
    19741 gctaataatc tggttcgctt ccaattgcat ggccaaggtc aactggtcgg tgtagataac
    19801 ggagaacaag ccagccgtga acgctataag gcgcaagcag atggttcttg gattcgtaaa
    19861 gcatttaatg gtaaaggtgt tgccattgtc aaatcaactg aacaagcagg gaaattcacc
    19921 cttactgccc actctgatct cttgaaatcg aaccaagtca ctgtctttac tggtaagaaa
    19981 gaaggacaag aaaagactgt tttggggaca gaggtgccaa aagtacagac cattattgga
    20041 gaggcacctg aaatgcctac cactgttccg tttgtataca gtgatggtag tcgtgcagaa
    20101 cgtcctgtaa cctggtcttt agtagatgtg agcaagcctg gtattgtaac ggtgaaaggt
    20161 atggctgacg gacgagaagt agaagctcgt gtagaagtga ttgctcttaa atcagagcta
    20221 ccagttgtga aacgtattgc tccaaatact aacttgaatt ctgtagacaa atctgtttcc
    20281 tatgttttga ctgatggaag tgtacaagag tatgaagtgg acaagtggga gattgccgaa
    20341 gaagataaag ctaagttagc aattccaggt tctcgtattc aagcgaccgg ttatttagaa
    20401 ggtcaaccaa ttcatacaac ccttgtggta gaagaaggca atcctgcagc acctgtagtg
    20461 ccaactgtta ctgttggagg tgaagcagta acaggtctta ctagtcgaca accaatgcaa
    20521 tatcgtactc tatcttatgg tgcccaattg ccagaagtca cagcaagtgc tgaaaatgct
    20581 gatgtgacag ttcttcaagc aagcgcagca aacggcatgc gtgcaagcat atttgttcag
    20641 cctaaagatg gtggccctct tcaaacctat gcaattcaat tcctagaaga agcaccaaaa
    20701 attgctcact tgagcttgca agtggaaaaa gctgacagtc tcaaagaaga ccaaactgtc
    20761 aaattgtcgg ttcgagctca ctatcaagat ggaacgcaag ctgtattacc agctgataaa
    20821 gtaaccttct ctacaagtgg tgaaggggaa gttgtagtcc gaaaaggaat gcttgagttg
    20881 cataaaccag gagcagtcac tctgaacgct gaatatgagg gtgctacagg tcaaatcact
    20941 ctcactatcc aagtcaatac tgagaagaag attgcgcaat ccatccgtcc tgtaaatgta
    21001 gtgacagatt tgcatcagga accaagtctt ccagcaacag taacagttga gtatgacaaa
    21061 ggtttcccta aaactcataa agtcacttgg caagctattc cgaaagaaaa actagactcc
    21121 tatcaaacat ttgaagtact aggtaaagtt gaaggaattg accttgaagc gcgtgcaaaa
    21181 gtctctgtag aaggtatcgt ttcagttgaa gaagtcagtg tgacaactcc aatcgcagaa
    21241 gcaccacaat taccagaaag tgttcggaca tatgattcaa atggtcacgt ttcatcagct
    21301 aaggttgcat gggatgcgat tcgtccagag caatacgcta aggaaggtgt ctttacagtt
    21361 aatggtcgct tagaaggtac gcaattaaca actaaacttc atgttcgcgt atctgctcaa
    21421 actgagcaag gtgcaaacat ttctgaccaa tggaccggtt cagaattgcc acttgccttt
    21481 gcttcagact caaatccaag cgacccagtt tcaaatgtta atgacaagct catttcctac
    21541 aataaccaac cagccaatcg ttggacaaac tggaatcgta gtaatccaga agcttcagtc
    21601 ggtgtcctat tcggagattc aggtattttg agcaaacgct ccgttgataa tctaagtgtc
    21661 ggattccacg aagaccatgg agttggtgca ccgaagtctt atgtgattga gtattatgtt
    21721 ggtaagactg tcccaacagc tcctaaaaac cctagttttg ttggtaatga ggaccatgtc
    21781 tttaatgatt ctgccaactg gaaaccagtt actaatctaa aagcctctgc tcaactcaag
    21841 gctggagaaa tgaaccactt tagctttgat aaagttgaaa cctatgctgt tcgtattcgc
    21901 atggtgagag cagacaacaa actaggaacg tctatcacag aggtacaaat ctttgcgaaa
    21961 caagttgcgg cagccaagca aggacaaaca agaatccaag ttgacggtaa agacttagca
    22021 aacttcaacc ctgatttgac agactactac cttgagtctg tagatggaaa agttacggca
    22081 gtcacagcaa gtgttagcaa caatggcctc gctaccgtcg ttccaagcgt tcgtgaaggt
    22141 gagccggttc gtgtcatcgc gaaagctgaa aatggcgaca tcttaggaga ataccgtctg
    22201 cacttcacta aggataagaa cttactttct cataaaccag ttgctgcggt taaacaagct
    22261 cgcttgctac aagtaggtca agcacttgaa ttgccgacta aggttccagt ttacttcaca
    22321 ggtaaagacg gctacgaaac aaaagatttg tcagttgaat gggaagaagt tccagcagaa
    22381 aatctgacaa aagcaggtca atttaccgtt cgaggccatg tccttggtag tgattttgtt
    22441 gctgaggtca ctgtacgagt gacagacaaa ctaggcgaag ctctttcaga taaccctaac
    22501 tatgatgaaa acagtaacca ggcctttgct tcagcaacca atgatattga caaaaactct
    22561 catgaccgcg ttgactatct caatgacgga gatcattcag aaaatcgtcg ttggacaaac
    22621 tggtctccaa caccatcttc taatccagaa gtatcagcgg gtgtgatctt ccgtgaaaat
    22681 ggtaagattg tagaacggac tgttgctcaa gccaaacttc acttctttgc agatagtggt
    22741 acggatgcac caactaaact cgttttagaa cgctatgtcg gtccagagtt tgaagtgcca
    22801 acctactatt caaactacca agcctacgac gcagaccatc cattcaacaa tccagaaaat
    22861 tgggaagctg tgccttatcg tgcggataaa gacatcgcag ctggtgatga aatcaacgta
    22921 acatttaaag ctgtcaaagc caaagctatg agatggcgta tggagcgtaa agctgacaag
    22981 agcggtgttg cgatgattga gatgaccttc cttgcaccga gtgaattgcc tcaagaaagt
    23041 acgcaatcga agattcttgt agatggaaaa gaacttgctg atttcgctga aaatcgtcaa
    23101 gactatcaaa ttacctataa aggtcaacgg ccaaaagtct cagttgaaga aaacaatcaa
    23161 gtagcttcaa ctgtggtaga tagtggagaa gatagccttc cagtacttgt tcgcctcgtt
    23221 tcagaaagtg gaaaacaagt caaggaatac cgtatccact tgactaagga aaaaccagtt
    23281 tctgagaaga cagttgctgc tgtacaagaa gatcttccaa aactcgaatt tgttgaaaaa
    23341 gatttggcat acaagacagt tgagaaaaaa gattcaacac tgtatctagg tgaaactcgt
    23401 gtagaacaag aaggaaaaac tggtaaagaa cgtatcttta cagcgattaa tcctgatgga
    23461 agtaaggaag aaaaactccg tgaagtggta gaagctccga cagaccgcat cgtcttggtt
    23521 ggaaccaaac cagtagctca agaagctaaa aaaccacaag tgtcagaaaa agcagataca
    23581 aaaccaattg attcaagtga agctagtcaa actaataaag cccagttacc aaatacaggt
    23641 agtgcggcaa gccaagcagc agtagcaggt ttagctcttc taggtttgag tgcaggatta
    23701 gtagttacta aaggtaaaaa agaagactag aaattttgat accttcttta tcattaaaga
    23761 ccaaagaaaa actcttgtcc taaatagaag ataaagagtc tgggacaaaa tagttctcaa
    23821 ccacaaaaaa gctagatatt tccaattgcg gaactctagc tttttaattt tgagtcgttc
    23881 tcttattgta tagtagattg aaactagagt agtacacttc tacttctaaa acattgttag
    23941 aaatcgattt gactgtcctt atcgatttgt cctgttctta tttcatttca ttatgtttta
    24001 ggaggttatt ggccataagt accaatccca tgtcaattct cacttgacgc ttgcctctca
    24061 gattacatct cttgtaaccc aaacaagcct ttaactgccc aaagacaggt tccacatcaa
    24121 tcttgcgttg agcgaaaatc tgtctacctt ggggagataa aagcgcctga cattctttag
    24181 ctttcaagtt ttgatagcgt tcgttcatat atagccccct tttgaggggc tgattcaggt
    24241 tcgtcggcat agtaaacctt gatttcctgt tgaaagtctg tctgtgtttt ctgatgtttg
    24301 gtatggtgaa aacgataata ccagccatca ggatgtgtgt agctatcctc cttgtcatta
    24361 tagtgccaat tcgctaagtt tttagctgac tgtttatacc ctctcttttg ttccttatca
    24421 aacatggcat atttaatcag aaggggagtg atttcttctt gaaaatagac ttgtatctgt
    24481 tcttgaagtt tggcggagaa tttctctgtc gttttcttcc acacaaaact atacttgttg
    24541 gcattggatt caatcttagt tccgtcaata aacaaacaat ctaaggtcac taactcttcc
    24601 atttttcaat ttttcgacca gagaaaatcc cttgtgaata gacaaataga agagtagata
    24661 caagcatttt agggtgataa gacgggcgat caaaggcatg atagaaggcg tagaagtgat
    24721 gttcctccaa ggtattcacc actttttcaa tagtaaagac gagatggtct tgtggtaaga
    24781 aggaactgat ttctagtggt aaagttgttt gatttgtgtt atagtgaata tgcatgggat
    24841 agcctttcta aatggtttat taagcaattc tattttacca agactatcgt aaccatgcaa
    24901 aaaagcaacg gcaaatccgt tgcctttttg gatataagag actattgtcc catactcttt
    24961 tctttgtata aaattgtata gtgttattgt ctatactatt ttgtagagaa agcaaaaatc
    25021 cctagaaaat gcttagggat tcgactattt cattaagaac aattcaacaa tcatttctat
    25081 atacatgata agggttaata agaatcctgc acgccagaag aatttgatga atttaggata
    25141 gtaaaagctg cgttttttca aaaggaagaa aaagacgaga ataatggcta ggatcgagag
    25201 ggctagcccc agtctaggga ggaaattatg ggtaaaggtt ttagctgtaa tcaagtaata
    25261 ctcaaatacc aagactggaa aagccaaatc cgcaaagttt cgtcctagtt tttttaatct
    25321 aaaaagtttg gttaggataa tgcagatgac taaggtcagt atcaataata aaatagatgc
    25381 taatttcatt aaaatcatac ccatattgta tcataaaaaa aggctaatgg aaacgagaag
    25441 cagaggaatt tataggaaag tcaggctttt gagattgtgg gtgatttttg ttataatgaa
    25501 agttataaaa tcttataata ccttgaatga ttattatcga aaactctttg gagaaaagac
    25561 ttttaaagtc cctattgatg cgggatttga ctgtcccaat cgtgatggaa ctgtggctca
    25621 tggaggctgt actttttgta cggtttcagg ttctggagat actattgtag ccccagatgc
    25681 gcctatccgt gagcaatttt ataaggaaat tgactttatg caccgtaagt ggccggatgt
    25741 tcagaagtat ctggtttatt ttcaaaattt taccaacacc catgaaaagg tggaagttat
    25801 tcgagagcgt tatgaacagg ctatcaatga gccaggtgtg gtaggaatca atattggaat
    25861 gcgcccagac tgtttaccag acgaaaccat cgaatatttg gctgagttat cggagtgcat
    25921 gcatgtgacg gttgaattgg gcttgtagac tacttatgaa gcaacttctg acctgattaa
    25981 ccgtgcgtat tcttatgaat tgtaggtgga aacggtcaag cgtttgagaa agtatcccaa
    26041 gattgagatt gtttcccatt tgattaatgg tttgcctggt gaaacccatg agatgatggt
    26101 tgaaaatgtc cgccgttgtg tcacgaataa cgatattcaa gggattaaac tgcatttgct
    26161 ccatcttatg acaaatactc gtatgcaacg agattaccat gagggacgtt tacaattgat
    26221 gagtcaggac gaatatgtca gggtcatctg tgaccaactg gaaatcattc ccaaacatat
    26281 cgtcatccat cgaatcacag gagatacacc tagggatatg ctgattgggc ttatgtggag
    26341 cctcaataaa tgggaagctc tcaacagcat taagatggag atgcgacgtc gtggaagtgt
    26401 tcaaggatgt aaggctgtaa aacaggagtt tgaaaatgaa aagaccactt gagatggcac
    26461 atgatttttt ggctgaggtc gtgacaaaag aggatgtcgt agtggatgcg actatgggaa
    26521 atggtcatga cacgcttttt ttagccaagc tagccaagca agtctatgcc tttgatattc
    26581 agaagcaagc cttggaaaag acccaagagc gtttgcatca ggctggcttg acaaatgccc
    26641 agttaatctt gcaaggccat gagacactgg accagtttgt gacaaaagct aaggcaggga
    26701 tttttaatct gggctatttg ccgtcagctg ataagtctgt catcacccga ccgcagacaa
    26761 cgattgaggc attagaaaag ctatgtggct tacttgtcaa aggtggacga attgctatta
    26821 tgatttacta tggtcatgaa ggaggcgacc tcgagagaga tgctgtcttg gattttgtga
    26881 tccagttgaa ccaacaagag tacacagctg ccatttaccg aactttaaac caagtcaaca
    26941 acccgccgtt tttagtgatg attgaaaaat tagagagata cagacatgga taaacaatac
    27001 ctacacgaaa agctggatgc catgcgccag aattttgttg aatcaactca ccacgaacga
    27061 gcggtgggcg tgctagacca agcgcatatg agcaaaaaaa tgcttaaaat caagaaaaaa
    27121 ttagttgctc ttgaaatgga acggtgccag agaaaaattg agcacaaaga ctgttccaag
    27181 attgaccaaa aaatcaaaga gcagaaggag atatttgaat cctgttgtaa aaaagattaa
    27241 ggaggacgtg cgtggaatta ctgatttacc tcatcctatt tttactggtt ttgattgtct
    27301 caagtacaac caataagctc ctaccctttt tgcctctccc tttggtgcag attcttttgg
    27361 gaattgtgat tggtctcttt ttacctaata ctgactttca ccttaatacg gagttgtttt
    27421 tggcactggt tatcggcccc ttgcttttcc gagaggctga agaagcagat gttacggcta
    27481 ttttaaaaca ctggcgaatc attgtttatc tcatatttcc agtgattttt atctcgaccc
    27541 tgagtttggg tggcttggcc catcttcttt ggttcagcct tcccttggca gcttgcttgg
    27601 ctgttggggc agcccttggt cctacggact tggtggcctt tgcctctctt tcggagcgtt
    27661 ttagctttcc taagcgcgtg tccaatattc ttaagggcga aggactcttg aatgatgctt
    27721 ctggtttggt ggcttttcag gtagctttga cagcttggac aactggagct ttttctctgg
    27781 ggcaagctag cagttcgctc atcttttcaa tcctaggcgg ttttttaatt ggatttttaa
    27841 cagccatgac caaccgcttc ctccatacct tcttgctaag tgtgcgcgca acggatattg
    27901 ccagtgaact tttattagaa ttgagtttgc ctctagtgac cttctttctg gcagaagaag
    27961 tccatgtttc agggattatt gccgtcgtag ttgctggaat tttaaaggca agtcgcttca
    28021 agaaaatcac gctcctcgaa gcccaagtgg atacggtgac cgagacggtc tggcatacag
    28081 tgacctttat gctcaacggt tctgtctttg tgattttagg gatggagttg gaaatgatag
    28141 cagaacctat cttgaccaat ccaatctata atcctctact tttattgcta tctctcatcg
    28201 cccttacctt tgtcctcttt gtcattcgtt ttattatgat ctatggctat tatgcctata
    28261 gaacccgacg cctcaagaaa aagctaaata agtatatgaa ggacatgttt ctcttgacct
    28321 tttcaggtgt taagggaacg gtgtcgattg ctacgattct cttgatacca agtaatctag
    28381 aacaggagta tcctctcttg cttttccttg ttgcaggtgt gacgcttgtc agctttttaa
    28441 caggtctctt ggtcttgcct catctttctg atgaagagga agaaagcaag gattatctca
    28501 tgcatatcgc cattttgaat gaagtaacgc tagagttgga aaaagagttg gaagacacca
    28561 gaaataaact tcccctctat gcggctattg acaattatca tggacgtatt gaaaatctca
    28621 ttttaagcca agaaaaccag gatgatcaag aagattgggc tgctttgaaa ctcttgattc
    28681 ttagtattga aagtgatggt ttggaacagg cctatgaaga ggggaacatt agcaatcgtg
    28741 cttaccgagt ttaccaacgt tatctgaaaa atatagaaca aggaatcaat cgtaaacttg
    28801 cctcaagact gacctattat ttccttgttt ctttgcggat tttacgtttt ctccttcatg
    28861 aagtttttac tctcggaaag accttccgta gctggaagaa caaggagcaa agccgtctcc
    28921 gtgctcttga ttatgaccaa attgcagagc tctatcttgc caatacggag atgattattg
    28981 aaagtttgga aaacctgaag ggagtctaca gccgctcttt gattagtttt atgcaggagt
    29041 ctcgtcttcg agaaacaact attattagca gtggtgcctt tgtcgaacgg gttatcaatc
    29101 gtgtcaaacc caacaatatc aatgaaatgc tgagaggcta ttatctggag cgcaagttga
    29161 ttttcgaata cgaagaaaaa cgattgatta cgactaagta tgccaagaaa ttacgacaaa
    29221 atgtaaataa cttagagaac tattccttga aggaagctgc caataccctg ccgtatgata
    29281 tggtggaatt ggtaagaaga aattagttaa tattcttcga aaatctcttc aaaccacgtc
    29341 agcgtcgcct taccgtatgt atgtgactga cttcgtcagt cttatctaca acctcaaaac
    29401 agtgttttga gcagcttgcg gctagctttc tagtttgctc tttgattttc attgagtata
    29461 agattataaa tgaaggagta tgacatgaaa aagtggtgga aagagctgat agacaagcct
    29521 ttattaaaag cttttttgca ttattatcaa gcatcagata gtgagttgac cagtgtcgca
    29581 gtagcctact attggttgat ttcgattttc cccctgcttt tggtggtggt caatatcctc
    29641 ccctattttc agattcctgt gggagaattt ttgggcttta tgaaagacgt tctgccccca
    29701 agcctctatg aaggtgtgga aaaaatagcc agagaagttt tgacgcaacc ttcaacaggt
    29761 ttattgagtt tttctgtttt atcggcgtta tggagttttt caaaatctat gaatttcttg
    29821 caaaaagctt ttaacaaggc ttatggcgtc gaaaagagtc gtggacttat ttcccatcag
    29881 atgctaagtc tcctagtcag ttttggcttg cagatcctct ttgcgtttgc cttgtttttg
    29941 atcttatttg gtcagatgat tttggcttta cttgctcatt attggacaaa agatggcatt
    30001 atctatcagg ctttacaagg gttggcaggt cctctgattt acgccctcct ctttgctatc
    30061 ttggtcatgc tttattattt tcttcccaat ctatctaaca ggaaaattag ctatacccta
    30121 ccaggcagtg cctttgttct cttagtgatt ttaggtttac taactctgtt ctctagttat
    30181 ctcaattact atgtccatca tttggtggat gtccgaattt taggttccgt tcttcttgtt
    30241 gttatgatgt tttggtttat cttgattgct aaaattgtta tcctaggcgc ggttatcaat
    30301 gccagtatgc agagtttgaa agatccggtc tttaaaaaag actaactatt tatccattac
    30361 aaaagcgcat agtatcaaga ctttatagaa ccttgatact atgcgctttt gtgctttgac
    30421 agttttttgt atagtttttg tccaagattt ctaaatcatc tgattaaatt cctattttcc
    30481 cctatcattg tccctgtttt ttcgaaaatg gaaggagtat aataaatcta tcaataaaat
    30541 gataggagga actttatggg tcatattttc ttttttctaa gtgtcttttt ggcagggatt
    30601 ctatccttct tttctccttg tatcttacct ttgttaccgg tctatacagg agtgttacta
    30661 gatgataagg atggtgctca ggcttctagc ggcaaatttt caatctcagt tactagttta
    30721 ttacgaactc tggcctttat agcaggaatt tcctttatat ttattttgtt gggctatgga
    30781 gctggttttt taggcgattt gctttatgct tcttggttcc aatatcttac tggggcaatt
    30841 attatccttc ttggtttgca ccaaatggag attctacact ttaaggagct ttataaggaa
    30901 aagaggctac aactgcaagg acaggggcaa aatggtaagg gctatagtca ggcattttta
    30961 ttgggcttga cctttagttt tgcttggacg ccttgcgtgg ggccggttct ggggtctgtt
    31021 ttggccttgg cggcttcagg tggttcagga gcttggcagg gagctggtct catgttggtg
    31081 tatacgctgg gcttggcgct accattcttg cttctagctc tgacctctag ttatgttttg
    31141 aaacatttcc gaaaacttca tccctatctc ggaatcctca aaaaagtggg tggttttctc
    31201 attattgtga tgggactctt ggttctgttt ggaaatgctt caattttaag tcaattattt
    31261 gaataaaatg gaaaggaata tcaatatgaa aaaatggcaa acatgtgttc ttggagcagg
    31321 ttcgctcctt tgtttgacgg cttgttcagg caagtccgtg actagtgaac accaaacgaa
    31381 agatgaaatg aagacggagc agacagctag taaaacaagc gcagctaaag ggaaagaggt
    31441 ggctgatttt gaattgatgg gagtagatgg caagacctac cgtttatctg attacaaggg
    31501 caagaaagtc tatctcaaat tctgggcttc ttggtgttcc atctgtctgg ctagtcttcc
    31561 agatacggat gagattgcta aagaagctgg tgatgactat gtggtcttga cagtagtgtc
    31621 accaggacat aagggagagc aatctgaagc ggactttaag aattggtata agggattgga
    31681 ttataaaaat ctcccagtcc tagttgaccc atcaggcaaa cttttggaaa cttatggtgt
    31741 ccgttcttac ccaacccaag cctttataga caaagaaggc aagctggtca aaacacatcc
    31801 aggattcatg gaaaaagatg caattttgca aactttgaag gaattagcct aggaggtgtc
    31861 ttatgaatga taagttaaaa atcttcttgt tgctaggagt attttttcta gccataaccg
    31921 gtttctatgt tctattgata cgaaatgcag ggcagacaga tgcctcgcaa attgaaaagg
    31981 cggcagttag ccaaggagga aaagcagtga aaaaaacaga aattagtaaa gacgcagact
    32041 tgcacgaaat ttatctagct ggaggttgtt tctggggagt ggaggaatat ttctcacgcg
    32101 ttcccggggt gacggatgcc gtttcaggct atgcaaatgg tagaggagaa acaaccaagt
    32161 acgaattgat taaccaaaca ggtcatgcag aaaccgtcca tgtcacctat gatgccaagc
    32221 aaatttctct caaggaaatc ctgcttcact atttccgcat tatcaatcca accagcaaaa
    32281 ataaacaagg aaatgatgtg gggacccagt accgtactgg tgtttattac acagatgaca
    32341 aggatttgga agtgattaac caagtctttg atgaggtggc taagaaatac gatcaacctc
    32401 tagcagttga aaaggaaaac ttgaagaatt ttgtggtggc tgaggattac catcaagact
    32461 atctcaagaa aaatccaaat ggctactgcc atatcaatgt taatcaggcg gcctatcctg
    32521 tcattgatgc cagcaaatat ccaaaaccaa gtgatgagga attgaaaaag accctgtcac
    32581 ctgaggagta tgcagttacc caggaaaatc aaacagaacg agctttctca aaccgttact
    32641 gggataaatt tgaatccggt atctatgtgg atatagcaac tggggaacct ctcttttcat
    32701 caaaagacaa atttgagtct ggttgtggct ggcctagttt tacccaaccc atcagtccag
    32761 atgttgtcac ctacaaggaa gataagtcct acaatatgac gcgtatggaa gtgcggagcc
    32821 gagtaggaga ttctcacctt gggcatgtct ttacggatgg tccacaggac aagggcggct
    32881 tacgttactg tatcaatagc ctctctatcc gctttattcc caaagaccaa atggaagaaa
    32941 aaggctacgc ttatttacta gattatgttg attaatactc ttcgaaaatc tcttcaaacc
    33001 acgtcagcgt cgccttaccg tatgtagggt tactgacttc gtcagtttta tctacaacct
    33061 caaagcggta ctttgagaaa cctgtggcta tcttcctagt ttactttttg atttttattg
    33121 agtataagag gtctttccta agcagttaga ggagaatttt gctatactga tactagtaag
    33181 tggtaaagga gcagatcatg acctacacaa tcttaatcgt agaagatgaa tatctggtaa
    33241 gacaaggttt gactaaactg gtcaatgtag cagcctacga tatggaaatc attggtcagg
    33301 ctgaaaatgg aaggcaggct tgggaattga tccaaaagca ggtgccagat atcattttaa
    33361 ccgatatcaa catgcctcat ctaaatggca tccagttggc cagtctggta cgagaaacct
    33421 atcctcaggt tcatttggtc tttttaacag gttacgatga ttttgattat gccttgtctg
    33481 ctgtcaaact aggtgtggac gactacctgc tcaaaccctt ttctcgtcag gatattgagg
    33541 aaatgttggg gaaaatcaaa caaaaactag acaaggaaga gaaagaagag cagttacaag
    33601 atttattgac taataggttt gaaggaaaca tggcccagaa aatccagtct catctggctg
    33661 atagccaatt tagtttaaag tctttagcca gtgacttagg ttttagtccg acctatctga
    33721 gttccttgat taagaaagag ttgggcttgc cttttcagga ttatctggtg agagaacgtg
    33781 ttaaacaagc caagctcttg cttttaacta cagatctgaa gatttatgag atcgcagaga
    33841 aggttggttt tgaagatatg aactatttta cccaacgttt taagcagatt gcaggtgtga
    33901 cacctcgtca gtttaagaag ggagaagacc gatgaagcgt tcttctcttt tagttagaat
    33961 ggttatttcc atctttctgg tctttctcat tctcctagct ctggttggaa ctttctacta
    34021 tcaatcaagt tcttcagcca ttgaggccac cattgagggc aacagccaaa cgaccatcag
    34081 ccagactagc cactttattc agtcttatat caaaaaacta gaaaccactt cgaccggttt
    34141 gacccagcag acggatgttc tggcctatgc tgagaatccc agtcaagaca aggtcgaggg
    34201 aatccgagat ttgtttttga ccatcttgaa gtcagataag gacttgaaaa ctgttgtgct
    34261 ggtgaccaaa tctggtcagg tcatttctac agatgacagt gtgcagatga aaacttcctc
    34321 tgatatgatg gctgaggatt ggtaccaaaa ggccattcat cagggagcta tgcctgtttt
    34381 gactccagct cgtaaatcag atagtcagtg ggtcatttct gtcactcaag aacttgttga
    34441 tgcaaaggga gccaatcttg gtgtgcttcg tttggatatt tcttatgaaa ctctggaagc
    34501 ctatctcaat caactccagt tggggcagca gggctttgcc ttcattatca atgaaaacca
    34561 tgaatttgtc taccatcctc aacacacagt ttatagttcg tctagcaaaa tggaggctat
    34621 gaaaccctac atcgatacag gtcagggtta tactcctggt cacaaatcct acgtcagtca
    34681 agagaagatt gcaggaactg attggacggt acttggcgtg tcatcattgg aaaagttaga
    34741 ccaggttcgg agtcagctct tgtggacctt gcttggggcc agtgtcacat ctcttcttgt
    34801 ctgtctctgc ttagtgtggt tcagtcttaa acgctggatt gctcctttga aggatttgag
    34861 agaaaccatg ttggaaattg cttctggtgc tcaaaatctt cgtgccaagg aagttggtgc
    34921 ctatgaactg agagaagtaa ctcgccaatt taatgccatg ttggatcaga ttgatcagtt
    34981 gatggtagct attcgtagcc aggaagaaac gacccgtcag taccaacttc aagccctttc
    35041 gagccagatt aatccacatt tcctctataa cactttggac accatcatct ggatggctga
    35101 atttcatgat agtcagcgag tggtgcaggt gaccaagtcc ttggcaacct atttccgctt
    35161 ggcgctcaat caaggcaagg acttgatttg tctctctgac gaaatcaatc atgtccgcca
    35221 gtatctcttt atccagaaac aacgctatgg agataagctg gaatacgaaa ttaatgaaaa
    35281 tgttaccttt gataatttag tcttacccaa gctggtccta caaccccttg tagaaaatgc
    35341 tctttaccat ggcattaagg aaaaggaagg tcagggccat attaaacttt ctgtccagaa
    35401 acaggattcg ggattggtca tccgtattga ggatgatggc gttggcttcc aagatgctgg
    35461 tgatagtagt caaagtcaac tcaaacgtgg gggagttggt cttcaaaatg tcgatcaacg
    35521 gctcaaactt cattttggag ccaattacca gatgaagatt gattctagac cccaaaaagg
    35581 gacgaaagtt gaaatatata taaatagaat agaaactagc taactcccag tcaattctgg
    35641 gagttttatg cgtaattggg caaactttct aggttgtcta tcttgctaaa aacaagaaaa
    35701 aacggtatga tagaagagtg acaacagagg taacagagat gaacgagaca cagattcaaa
    35761 gagaaacacg tcaggtagtg gaagatgttt tagaaaagac caatttgaag cagggggccc
    35821 tttttgtttt aggtctatct tctagtgagg tgctaggtgg tcagattggg aaagaatcca
    35881 gtcaagagat tggtgagctg atagtggaga ctatcttggg tattctaagt agtagaggta
    35941 tccatttagc agttcaaggt tgtgagcatg tcaatcgggc tctcgttgtt gaacgtcagg
    36001 tggcagagca gtttggtctg gaaattgtca gtgtccatcc tactcttcat gcaggaggtt
    36061 cggggcagtt ggcagccttt aagtttatgc aggatccagt tgaggttgaa tttatcaagg
    36121 ctcatgctgg attggatatc ggagacactg caattggcat gcatgtcaag catgttcagg
    36181 ttccgattcg ccctattttg agagagattg gtcatgccca tgtaacggca ctggctagtc
    36241 gtccaaaatt aatcggaggt gcgcgtgcgc actatccgca agacgctatt agaaagtctt
    36301 gagaatgaat aaaggagata aaagtgttta aaaaagaccg tttttcaatt cgtaagatta
    36361 agggagttgt aggctctgta tttcttggaa gccttttgat ggctccttct gtagtggacg
    36421 cagccaccta tcactatgta aataaagaga ttatttcaca agaagctaaa gatttaattc
    36481 agacaggaaa gcctgacagg aatgaagttg tatatggttt ggtgtatcaa aaagatcagt
    36541 tgcctcaaac agggacagaa gcatctgttt tgacagcttt tggtttgctg actgttggga
    36601 gcttgctttt aatctacaag agaaagaaaa ttgctagcgt ctttctagtt ggagctatgg
    36661 gattggtagt tcttcctagt gcaggggctg tagacccagt tgcgacccta gcgctggcta
    36721 gtcgagaggg tgttgttgaa atggagggct atcgctatgt tggttatcta tcaggtgaca
    36781 tcctcaaaac gcttggcttg gacactgttt tagaagaaac ctcagcaaaa cctggagagg
    36841 tgactgtagt cgaagttgag actcctcaat caacaacaaa tcaggagcaa gctaggacag
    36901 aaaaccaagt agtagagaca gaggaagcac ctaaaacaga agaaagtcca aaggaagaac
    36961 caaaatcgga gataaaacct actgacgaca cccttcctaa agtagaagag gggaaagaag
    37021 attcagcaga accagctcca gttgaagaag taggtggaga agttgagtca aaaccagagg
    37081 aaaaagtagc agttaagcca gaaagtcaac catcagacaa accagctgag gaatcaaaag
    37141 ttgaaccacc agtagaacaa gcaaaaggcc cagaacaacc cgtgcaacct acacaagctg
    37201 agcaaccaag gataccaaaa gattcatcac aaccagaaga tcctaaagaa gataggggag
    37261 cggaagagac accgaaacaa gaagatacac cgaaacaaga agatacacag ccagaagtag
    37321 tagaaacaaa agatgaggct gctaatcaac ctgttgaaga accaaaagtt gaaacgcctg
    37381 ctgtagaaaa acaaacggaa ccaaaagttg aacaagtagg tgaaccagtc gagccaagtg
    37441 aagacgaaaa ggcaccagtc tctccagaaa agcaaccaga agctcctgaa gagaaggctg
    37501 tagaggaaac accgaaacca gaagataaaa taaagggtat tggtactaaa gaaccagttg
    37561 ataaaagtga gttaaataat caaattgata aagctagttc agtttctcct actgattatt
    37621 ctacagcaag ttacaatgat cttggacctg ttttagaaac tgcaaaaggt gtctatgctt
    37681 cagagcctgt aaaacagcct gaggtaaata gcgagacaaa taaacttaaa acggctattg
    37741 acgctctaaa cgttgataaa agtgaattac aggaacaatt aagagttgct gaacaaaaac
    37801 aacaagctga ctatagcgct aaaacttgga gggaattcaa aattgctgaa cttcaagcta
    37861 aagaaatcaa caaccaaact acaccacttc ctaaacaaag tgaaatagat gcagctacta
    37921 aggctcttca agacgctctt caagctcttg ctgtagataa aactgtatta caaaacgcta
    37981 ttaacacagc taatagcaaa cgtgaagaag agtatactgc tcagacatgg aaagcgttag
    38041 aagatgctct tacagcagtg aatcctgtta atgaagatga aactgcaact caaagcaaag
    38101 tagacgaagc tactagaaac ttagaagaag ctatcaataa cctagttcta ttaactgaaa
    38161 aaccggtatt aacatttatt gagactgata agaaagcatt agaacgtgaa gtagttgcta
    38221 agtattctct agaaaaccaa aataaaacaa aaattaaatc aatcacagct actctgaaaa
    38281 aaggagaaac agttgttagc actgtagagc ttataggcga tgatgtaact aatgaaacta
    38341 taacctctgc atttaagaat ctagagtact acaaagaata caccctatct acaactatgg
    38401 tttacgatag aggtgacggt gatgtaacag aaatcttaga taatcaacca atccaactag
    38461 atcttaaaaa agttgagctt aaaaatatta aacgtacaga tttaatcaaa tacgaaaatg
    38521 gaaaagaaac taatgaatca ctaataacaa ctgttcctga tgataagcgg aattattatt
    38581 taaaaataac ttcaaagaat caaaaaacta cattactagc tgttaaaaat atagaagaaa
    38641 ctacggttaa cggaacacct gtatataaag ttacagcaat cgcagacaat ttagtctcta
    38701 gaactgctga taataaattt gaagaagaat acgttcacta tattgaaaaa cctaaagtcc
    38761 acgaagataa tgtatattat aacttcaaag aattagtgga ggctattcaa aacgatcctt
    38821 caaaagaata tcgtctggga caatcaatga gcgctagaaa tgttgttcct aatggaaaat
    38881 catatatcac taaagaattt acaggaaaac ttttaagttc tgaaggaaaa caatttgcta
    38941 tcactgagtt ggaacatcca ttatttaatg tgataacaaa cgcaacgata aataatgtga
    39001 attttgaaaa tgtagagata gaacgttctg gtcaagataa tattgcatca ttagccaata
    39061 ctatgaaagg ttcttcagtt attacaaatg tcaaaattac aggcacactt tcaggtcgta
    39121 ataatgttgc tggatttgta aataatatga atgatggaac tcgtattgaa aatgttgctt
    39181 tctttggcaa actacactct acaagtggaa atggctctca tacaggggga attgcaggta
    39241 caaactatag aggaattgtt agaaaagcat atgttgatgc tactattaca ggaaacaaaa
    39301 cacgcgccag cttgttagtt cctaaagtag attatggatt aactctagac catcttattg
    39361 gtacaaaagc tctcctaact gagtcggttg taaaaggtaa aatagatgtt tcaaatccag
    39421 tagaagttgg agcaatagca agtaagactt ggcctgtagg tacggtaagt aattctgtca
    39481 gctatgctaa gattatccgt ggagaggagt tattcggctc taacgacgtt gatgattctg
    39541 attatgctag tgctcatata aaagatttat atgcggtaga gggatattcg tcaggtaata
    39601 gatcatttag gaaatctaaa acatttacta aattaactaa agaacaagct gatgctaaag
    39661 ttactacttt caatattact gctgataaat tagaaagtga tctatctcct cttgcaaaac
    39721 ttaatgaaga aaaagcctat tctagtattc aagattataa cgctgaatat aaccaagcct
    39781 ataaaaatct tgaaaaatta at
//
LOCUS       DAVLGK010000016        39210 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLGK010000016 DAVLGK010000000
VERSION     DAVLGK010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39210
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.016"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            2..74
                     /locus_tag="VXE01_000912"
     tRNA            2..74
                     /locus_tag="VXE01_000912"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            99..171
                     /locus_tag="VXE01_000913"
     tRNA            99..171
                     /locus_tag="VXE01_000913"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:132..134,aa:Lys,seq:ttt)
     gene            177..258
                     /locus_tag="VXE01_000914"
     tRNA            177..258
                     /locus_tag="VXE01_000914"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Leu,seq:tag)
     gene            277..349
                     /locus_tag="VXE01_000915"
     tRNA            277..349
                     /locus_tag="VXE01_000915"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Thr,seq:tgt)
     gene            372..443
                     /locus_tag="VXE01_000916"
     tRNA            372..443
                     /locus_tag="VXE01_000916"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:404..406,aa:Gly,seq:gcc)
     gene            451..536
                     /locus_tag="VXE01_000917"
     tRNA            451..536
                     /locus_tag="VXE01_000917"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:485..487,aa:Leu,seq:taa)
     gene            546..619
                     /locus_tag="VXE01_000918"
     tRNA            546..619
                     /locus_tag="VXE01_000918"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Arg,seq:acg)
     gene            635..708
                     /locus_tag="VXE01_000919"
     tRNA            635..708
                     /locus_tag="VXE01_000919"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:669..671,aa:Pro,seq:tgg)
     gene            714..787
                     /locus_tag="VXE01_000920"
     tRNA            714..787
                     /locus_tag="VXE01_000920"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:748..750,aa:Met,seq:cat)
     gene            801..874
                     /locus_tag="VXE01_000921"
     tRNA            801..874
                     /locus_tag="VXE01_000921"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Ile,seq:cat)
     gene            885..974
                     /locus_tag="VXE01_000922"
     tRNA            885..974
                     /locus_tag="VXE01_000922"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Ser,seq:tga)
     gene            985..1058
                     /locus_tag="VXE01_000923"
     tRNA            985..1058
                     /locus_tag="VXE01_000923"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1019..1021,aa:Met,seq:cat)
     gene            1062..1134
                     /locus_tag="VXE01_000924"
     tRNA            1062..1134
                     /locus_tag="VXE01_000924"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1095..1097,aa:Phe,seq:gaa)
     gene            1154..1224
                     /locus_tag="VXE01_000925"
     tRNA            1154..1224
                     /locus_tag="VXE01_000925"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1186..1188,aa:Gly,seq:tcc)
     gene            1260..1333
                     /locus_tag="VXE01_000926"
     tRNA            1260..1333
                     /locus_tag="VXE01_000926"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1294..1296,aa:Ile,seq:gat)
     gene            1340..1427
                     /locus_tag="VXE01_000927"
     tRNA            1340..1427
                     /locus_tag="VXE01_000927"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1374..1376,aa:Ser,seq:gct)
     gene            complement(1560..1997)
                     /locus_tag="VXE01_000928"
     CDS             complement(1560..1997)
                     /locus_tag="VXE01_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0749852.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEA
                     TNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(2204..3139)
                     /locus_tag="VXE01_000929"
     CDS             complement(2204..3139)
                     /locus_tag="VXE01_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV0749853.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKA
                     KAASLFKATAPITRNELIIEIWRAFFETPSEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(3136..3996)
                     /locus_tag="VXE01_000930"
     CDS             complement(3136..3996)
                     /locus_tag="VXE01_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0749854.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVNLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            4104..6266
                     /locus_tag="VXE01_000931"
     CDS             4104..6266
                     /locus_tag="VXE01_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0749855.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRTTPLETRGHVAMMGNLGYELDLTSLSDEEKAEIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYKNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     ELQENGEVYSGAELMYAGLTVILSQGDFLSKQYIFRRL"
     gene            6301..7560
                     /locus_tag="VXE01_000932"
     CDS             6301..7560
                     /locus_tag="VXE01_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0749856.1"
                     /translation="MKWYKKIGLLATTGLALVGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            7574..8440
                     /locus_tag="VXE01_000933"
     CDS             7574..8440
                     /locus_tag="VXE01_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0749857.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            8454..9287
                     /locus_tag="VXE01_000934"
     CDS             8454..9287
                     /locus_tag="VXE01_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0749858.1"
                     /translation="MKQDERKALIGKYILLILGSVLLLVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            9288..9368
                     /locus_tag="VXE01_000935"
                     /pseudo
     CDS             9288..9368
                     /locus_tag="VXE01_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            9507..10949
                     /gene="gtfA"
                     /locus_tag="VXE01_000936"
     CDS             9507..10949
                     /gene="gtfA"
                     /locus_tag="VXE01_000936"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV0749859.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGGDLIRLDAFAYAVKKLYTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRSVVKVLLNLFSFRNRSEAFDLEGTTEIETPTAQSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            11087..12280
                     /locus_tag="VXE01_000937"
     CDS             11087..12280
                     /locus_tag="VXE01_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0749860.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            12967..14946
                     /locus_tag="VXE01_000938"
     CDS             12967..14946
                     /locus_tag="VXE01_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0749861.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            15013..16509
                     /locus_tag="VXE01_000939"
     CDS             15013..16509
                     /locus_tag="VXE01_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0749862.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            16509..17435
                     /locus_tag="VXE01_000940"
     CDS             16509..17435
                     /locus_tag="VXE01_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0749863.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINVVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            17444..18511
                     /locus_tag="VXE01_000941"
     CDS             17444..18511
                     /locus_tag="VXE01_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749864.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            18522..19448
                     /locus_tag="VXE01_000942"
     CDS             18522..19448
                     /locus_tag="VXE01_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749865.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(19523..20722)
                     /locus_tag="VXE01_000943"
                     /pseudo
     CDS             complement(19523..20722)
                     /locus_tag="VXE01_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(20878..21588)
                     /gene="treR"
                     /locus_tag="VXE01_000944"
     CDS             complement(20878..21588)
                     /gene="treR"
                     /locus_tag="VXE01_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV0749866.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21773..23740
                     /gene="treP"
                     /locus_tag="VXE01_000945"
     CDS             21773..23740
                     /gene="treP"
                     /locus_tag="VXE01_000945"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV0749867.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLRDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEATKSAAKSNQNVV
                     QGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVSHELVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELISPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            23918..25543
                     /gene="treC"
                     /locus_tag="VXE01_000946"
     CDS             23918..25543
                     /gene="treC"
                     /locus_tag="VXE01_000946"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV0749868.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIKGPIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25799..26047
                     /locus_tag="VXE01_000947"
     CDS             25799..26047
                     /locus_tag="VXE01_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV0749869.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26254..27048
                     /gene="racE"
                     /locus_tag="VXE01_000948"
     CDS             26254..27048
                     /gene="racE"
                     /locus_tag="VXE01_000948"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV0749870.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNMMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27045..28016
                     /locus_tag="VXE01_000949"
     CDS             27045..28016
                     /locus_tag="VXE01_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV0749871.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            27992..28513
                     /locus_tag="VXE01_000950"
     CDS             27992..28513
                     /locus_tag="VXE01_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0749872.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28510..28971
                     /locus_tag="VXE01_000951"
     CDS             28510..28971
                     /locus_tag="VXE01_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0749873.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVLPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28962..29702
                     /gene="xerD"
                     /locus_tag="VXE01_000952"
     CDS             28962..29702
                     /gene="xerD"
                     /locus_tag="VXE01_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV0749874.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29702..30430
                     /locus_tag="VXE01_000953"
     CDS             29702..30430
                     /locus_tag="VXE01_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV0749875.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30449..31018
                     /locus_tag="VXE01_000954"
     CDS             30449..31018
                     /locus_tag="VXE01_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV0749876.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31005..31727
                     /locus_tag="VXE01_000955"
     CDS             31005..31727
                     /locus_tag="VXE01_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0749877.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31727..31969
                     /gene="yidD"
                     /locus_tag="VXE01_000956"
     CDS             31727..31969
                     /gene="yidD"
                     /locus_tag="VXE01_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV0749878.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFDLTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(32194..33159)
                     /locus_tag="VXE01_000957"
     CDS             complement(32194..33159)
                     /locus_tag="VXE01_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0749879.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEISFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33255..34007)
                     /locus_tag="VXE01_000958"
     CDS             complement(33255..34007)
                     /locus_tag="VXE01_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0749880.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIDSWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(34004..34960)
                     /locus_tag="VXE01_000959"
     CDS             complement(34004..34960)
                     /locus_tag="VXE01_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0749881.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILIGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(34950..35909)
                     /locus_tag="VXE01_000960"
     CDS             complement(34950..35909)
                     /locus_tag="VXE01_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0749882.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36332..37033)
                     /locus_tag="VXE01_000961"
     CDS             complement(36332..37033)
                     /locus_tag="VXE01_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV0749883.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKVYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKTFGDDYDTH
                     DGSCIRDYIYVLDLA"
     gene            37433..38497
                     /gene="pepA"
                     /locus_tag="VXE01_000962"
     CDS             37433..38497
                     /gene="pepA"
                     /locus_tag="VXE01_000962"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV0749884.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38519..38815
                     /locus_tag="VXE01_000963"
     CDS             38519..38815
                     /locus_tag="VXE01_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0749885.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
BASE COUNT        11232 a         7385 c         8709 g        11884 t
ORIGIN      
        1 aggtcccgta gtgtagcggt tatcacgtcg ccctgtcacg gcgaagatcg cgggttcgat
       61 tcccgtcggg accgtttaag gtaacgcaag ttattttaga ctcgttagct cagttggtag
      121 agcaattgac ttttaatcaa tgggtcactg gttcgagccc agtacgggtc atatatgcgg
      181 gtttggcgga attggcagac gcaccagatt taggatctgg cgcttaacgg cgtgggggtt
      241 caagtccctt aacccgcatt gagatataac aaatgagccg gcttagctca gttggtagag
      301 catctgattt gtaatcagag ggtcgcgtgt tcaagtcatg tagccggcat ttttagatag
      361 aagaaaacag tgcgaacgta gttcagtggt agaacaccac cttgccaagg tgggggtcgc
      421 gggttcgaat cccgtcgttc gcttagagag gccggggtgg cggaactggc agacgcacag
      481 gacttaaaat cctgcgattg gtaacgatcg taccggttcg attccggtcc tcggcataat
      541 atggagcacc cttagctcaa ctggatagag tacctgacta cgaatcaggc ggttagaggt
      601 tcgactcctc tagggtgcat ttttctattt aactcgggaa gtagctcagc ttggtagagt
      661 acttggtttg ggaccaaggt gtcgcaggtt cgaatcctgt cttcccgatt catggcggtg
      721 tagctcagct ggctagagcg tccggttcat acccgggagg tcgggggttc gatccccttc
      781 gccgctataa tgatcttgtc ggacctttag ctcagctggt tagagctctc ggctcataac
      841 cgagtggtcg taggttcaag tcctacaagg tccatttgaa tattggagga ttacccaagt
      901 ccggctgaag ggaacggtct tgaaaaccgt caggcgtgta aaagcgtgcg tgggttcgaa
      961 tcccacatcc tccttttata ttaacgcggg atggagcagc tcggtagctc gtcgggctca
     1021 taacccgaag gtcgtaggtt caaatcctgc tcccgcaata aggctcggta gctcagttgg
     1081 tagagcaatg gattgaagct ccatgtgtcg gcggttcgat tccgtctcgc gccattttat
     1141 tgatagtatt tatgcgggtg tagtttagtg gtaaaactac agccttccaa gctgttgtcg
     1201 cgagttcgat tctcgtcacc cgctttgaac tttgttcaaa ttaccaagtt ttttaacttg
     1261 ggcgcgtagc tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt
     1321 ccactcgtgc ccattaattg gagaattact caagaggctg aagaggacgg tttgctaaat
     1381 cgttaggtcg ggtaactggc gcaagggttc gaatccctta ttctccgttt taatgagagt
     1441 ttgtaactct cttttttatt tttagagaca ataaagcttc agatccgtaa aacttaattg
     1501 aattactaat ctgaagttat ttttatggct ctttgtcaac tgtagtgggt tgaagtcagc
     1561 taagctcgag aaaggacaaa tttcgtcctt tcttttttga tgttcaaagc gataaaaatc
     1621 cgttttttaa agttttcaaa gtttcgaaaa ccaaaggcat tgcacttgat aagtttgatg
     1681 agattattgg tcgcttccag tttggcgtta gaatagtgta gttgaagggc gttgacaatc
     1741 ttttctttat ctttgaggaa ggttttaaag acagtctgaa aaataggatg aacctgctta
     1801 agattgtcct caataagtcc gaaaaatttc tctggttcct ttttcttcat tagacttcca
     1861 caatcagggc aagatggagc ctcataatcc agcttagcga taatttcttt gtgggtatcc
     1921 atattgatga tatctagaat cttgatgttt gggtctttaa tatcgagcag ttttgtgata
     1981 aaatgtaatt gttccatatg aatctttcta atgatggttt tgtcgctttt cattataggt
     2041 catatgggac tttttttcta caacaaaata ggctccataa tatctataag ggatttaccc
     2101 actacaaata ttatagagcc aataaaactt cagatccgta aaacttaatt gaattactaa
     2161 tctgaagtta tttttatatc gtttatatta taattgtgtt attttacttc caactattga
     2221 gagaaatttc gccactattt agccagattt cttttccgtt atcacattga actaaaagtt
     2281 ttccattctc tgagatgtct ttagcaagtc ccttgtagtc tttttgctct agtgtgaaag
     2341 tgacttcttt tcctagaatg aatgactgtt ttttgtatag gtataatagc tcttctgatg
     2401 gtgtttcgaa gaaagcacgc cagatttcta tgatcaattc attccttgtt ataggagctg
     2461 tagctttaaa taagctggca gcttttgctt ttaattcctg agggaagtct ttaatagtga
     2521 aattgatacc tactccaata atgatatctg tgactaagcc agtttctaca gaggtcattg
     2581 cttcagtaag gattcctcca attttatgat tgtttagata gatatcattg acccatttta
     2641 tgtcgacatc tattaaagtt aggttcttaa tggctttgta gacagctcca gctacaagta
     2701 gtgtgtagga tggtaatttg tcatagggga gatttggttt aagatggagt gtcatataaa
     2761 taccaccttg tggtgagtag aaggaacgtt gaaaacggcc tcggcctgct gtttgatagg
     2821 aagctagata gagggtattt gcttcatggc ctaaatcaat tgcttctttt gcatctagtt
     2881 gtgttgattt tgtttcgggt ttaaagctga ctttaattgg aagattttct tctagaatct
     2941 ctggaagaat aaggtcacca ttcattagtt tatatcctct atttttgata ctatcaattt
     3001 caatgccttc ttgttctagt cgcttgatag ctttccaaat tgatgttcgg cttagggata
     3061 gtttttctgc gattttttct ccgctgatat agtcggtttc tttagatagg atttggtaga
     3121 cagcttggta ggatttcata atgttgcctt tctcactagt tggtattgag agtattcttt
     3181 tcttgtatga cttggagtct gattaaagta ttgtttataa gctttcgaaa aatggagtgg
     3241 atctgaaaaa cctaccgagt atgcaattac cttgatggac tcttgggtat tttcgagaag
     3301 ttgtctagct cggtgcattc gaacgtagag taggtattct ttgggtgata aggtattaaa
     3361 ttctttgaat acgcttgata agtagcttct gtgaacggat agttcttttg ctaaatcttg
     3421 aattgtaagt gattgaggat agtggctatc aattaatcgt ttgcattcaa gatagagttg
     3481 gtgggttgat gaaatattct tttttttctg attgggagca atagttccca gatgaaacat
     3541 cagttcatga agttgtccca tgatatggag ttgagctaat tcacttgatt ttgtaatctg
     3601 agcgaagcgg acaatgtctg agatgagttt tgcagtagtc tgggtatgac aagtttcaga
     3661 ttggatgaga taggattgat cagaaatttg agaaagagca aaataatcag gggatttccc
     3721 tccagtgatt cctaaccagt agtaggccca aggttcttta ctatctgctt gataaaaggt
     3781 tagttcctct ggttttaata gaaagaaatc tccttctttt aaattaacaa ttttaccctt
     3841 gtaatgaaat tttccttgtc ctttagtaat gtaatgtagg acgtatgtat cacgaatggc
     3901 tggaccaaaa gagtaattag gtgtgcattc ctcatatcca taaaagctta gggcaaggtc
     3961 gattgttcca gtctggtatt ctgaaaaaac taacatgtgc tacctcctac ctaacatttt
     4021 accatattct tgagacattt ttctatttta gaaagcgatt tcaggtgata aaatataatc
     4081 aataaagtga tgaggtgaag taaatgggag ttaggataga gaataatcta ttttatgttg
     4141 agagtaaaaa tctaagtttg attattgaaa atcgaaatgg ctacttactt ttgaaacatt
     4201 taggaaagac tattaagaac tataaaggtt ccaatagtgt ttatgaacga gaccatgcct
     4261 tttcaggaaa tccaacggct actaatcgaa cctttagttt agatactcag cgacagattt
     4321 ttggacaaca tggcttagga gattttagga aaccaaccat acaggttcag catagtgtaa
     4381 ctgaagtaac agactttcga tttgtagaag caaagatttt aaaaggtcag aatggtccac
     4441 agggcttacc ttctccacat agcatggacg atacagagac tcttgtctta atgttagaag
     4501 attctaaggc tcaacttagt ctgactttgt attatactac ttttaataat gatgcgacta
     4561 ttgctagcta cagtaaatta gataataata gtaatcagga agttgtcatc cataaagatt
     4621 tttcttttat ggctgatttt ccagctgcag attacgaaat agtaactctg cagggtgctt
     4681 atgctcgtga aaagactgtt agacgtcaac aggtagaaca aggaatcttt tcgattagct
     4741 caaaccgagg tgcttctggt catgctcaaa caccagctct tctactatgc gaacaaggag
     4801 tcacagagga tgctgggaat gtgtttgcta ttcaactaat gtatagtggc aactttgaag
     4861 cttttgttca aaaaaatcaa ttgaatgaag ttcgggtggc tattggcatt aatccagaaa
     4921 acttttcttg gaagttagcc cctgaggaat actttgaaac accggtagct ttagtgactc
     4981 attcagatca gggattaact ggtattagtc atgaaagtca gaattttgta ctgaagcaca
     5041 ttattctaag tgaattttct aaaaaagaac gtccaattct aatcaataac tgggaagcta
     5101 cttactttga ctttcagaga gaaaaactgt tagagttagc agatgaagct aagaaagttg
     5161 gcattgaact ttttgtatta gatgatggtt ggtttggcaa tcgttttgat gataatcgtg
     5221 ctttaggtga ttgggttgtt aatgaggaaa aactgggtgg aagtctagaa agtctgattt
     5281 cagctatcca tgaaagaggt ttgcagtttg gactttggtt agaacccgaa atgatttctg
     5341 tagatagtga tttgtatcgt caacatcctg actgggctat tcaggttcct gattatgagc
     5401 atacttattc tcggaatcaa ttagtactta atcttgccaa tcctcaggta gtagaatact
     5461 tgaaaagtgt cttagatcaa ctcctatctt atcatgagat tgattacatt aaatgggata
     5521 tgaaccgcaa tatcactaag ctagggaatg gattaactta tctagagaca cagatgcaat
     5581 ctcatcagta catgctgggg ctttacgaac tcgtttctta tctgacagag aagcacagcc
     5641 atattctctt tgagtcctgc tctggtggtg gtggacgaaa tgatcttggt atgatgcgct
     5701 atttcccaca agtctgggct agtgataata cagatgctat tgcacgttta ccaattcaat
     5761 acggttcatc ctatctctat ccaaccattt ctatgggggc tcatgtgtca gcagtaccga
     5821 atcatcagat ggggcgaacg acaccattag aaacacgtgg acatgtagca atgatgggaa
     5881 atttgggcta tgagcttgat ttgacaagtt tatcagatga agagaaagct gagattgcta
     5941 atcaggtgaa cttgtataaa gaattacgac cagtagttca gttaggacaa cagtatagac
     6001 taattaatcc tgatactgca tccaatgaag ctgctgtaca atttaattac aaaaatcaaa
     6061 cgattgtaac ctacgttcgc gttttgtcag ttgtagagac catggaaaca actttaaagt
     6121 taaaagattt ggatgaagag ggactatatg aattacagga aaatggcgaa gtttactcag
     6181 gtgcagaact catgtatgcg ggtttaactg ttattttatc ccaaggagat tttttgagta
     6241 aacagtatat ttttagaaga ctataattaa ggtgtataaa tttataaagg aggctttcca
     6301 atgaaatggt ataaaaaaat cggacttctt gcaactacag gtttagcttt ggttgggctc
     6361 ggcgcttgct ccaactatgg taaatctgcg gatggcacag tgaccatcga gtatttcaac
     6421 cagaaaaaag aaatgaccaa aaccttggaa gaaatcactc gtgattttga gaaggaaaac
     6481 cctaagatca aggtcaaagt cgtcaatgta ccaaatgctg gtgaagtatt gaagacacgc
     6541 gttctcgcag gagatgtgcc tgatgtggtc aatatttacc cacagtccat cgaactgcaa
     6601 gaatgggcaa aagcaggtgt ctttgaagat ttgagcaaca aagactacct gaaacgcgtg
     6661 aaaaatggct acgctgaaaa atatgctgta aacgaaaaag tttacaacgt tccttttaca
     6721 gctaatgctt atggaattta ctacaacaaa gataaattcg aagaactggg cttgaaggtt
     6781 cctgaaacct gggatgaatt tgaacagtta gtcaaagata tcgttgctaa aggacaaaca
     6841 ccatttggaa ttgcaggtgc agatgcttgg acactcaatg gttacaatca attagccttt
     6901 gcgacagcaa caggtggagg aaaagaagca aatcaatacc ttcgttattc tcaaccaaat
     6961 gccattaaat tgtcggatcc gattatgaaa gatgatatca aggtcatgga catccttcgc
     7021 atcaatggct ctaagcaaaa gaactgggaa ggtgctggct ataccgatgt tatcggagcc
     7081 ttcgcacgtg gggatgtcct catgacacca aatgggtctt gggcgatcac agcgattaat
     7141 gaacaaaaac cgaactttaa gattgggacc ttcatgattc caggaaaaga aaaaggacaa
     7201 agcttaaccg ttggtgcggg agacttggca tggtctatct cagccaccac caaacatcca
     7261 aaagaagcca atgcctttgt ggaatatatg acccgtccag aagtcatgca aaaatactac
     7321 gatgtggacg gatctccaac agcgatcgaa ggggtcaaac aagcaggaga agattcaccg
     7381 cttgctggta tgaccgaata tgcctttacg gatcgtcact tggtctggtt gcaacaatac
     7441 tggaccagtg aagcagactt ccataccttg accatgaact atgtcttgac cggtgataaa
     7501 caaggcatgg tcaatgattt gaatgccttc tttaacccga tgaaagcgga tgtggattag
     7561 gagtagagag actatgaaaa aagtattaca aaaatattgg gcatgggctt ttgtggtcat
     7621 ccccctcttg ttacaagcaa ttttcttcta tgtgccgatg tttcaaggag ccttttacag
     7681 ttttaccaac tggacaggat tgacttacaa ctacaaattt gtcggcttaa acaactttaa
     7741 gctcctcttc atggatccaa aattcatgaa tgcgattggc tttaccgcaa tcattacgat
     7801 tgccatggtg gttggtgaga ttgcactcgg gatcttcatt gcgcgtgtct tgaactctaa
     7861 aatcaaaggc caaaccttct tccgtgcttg gttcttcttc ccagctgttt tatctggttt
     7921 gacagtggct ttgatcttca agcaagtctt caactacggt cttccagcga ttgggaatgc
     7981 ccttcatatt gaatttctcc aaaccagtct tttagggact aagtggggag caatctttgc
     8041 ggctgtcttt gtccttcttt ggcaaggggt ggctatgccc atcatcatct tcctagctgg
     8101 tttgcaatct attccaactg agattacaga ggcagcaagg attgatggtg cgactagcaa
     8161 gcaagttttc tggaacattg aattgcctta cttgctacca agtgtctcta tagtctttat
     8221 cctagcccta aaaggtgggc tgactgcctt tgaccaagtc tttgccatga ccggtggtgg
     8281 tccaaacaat gccacaacct cacttgggct cttggtttat aactatgcct ttaaaaacaa
     8341 ccaattcggt tatgccaatg ccattgccgt aatcttgttc ttcttaattg tagtgatttc
     8401 gatcatccaa ttgagagtat ctaagaaatt tgaaatttaa gaggagaagc atgatgaaac
     8461 aagatgaaag aaaagccctg attggcaaat acattctatt gattctagga tcggttctgc
     8521 ttttagtgcc gctccttgct accctcttta gttccttcaa acccactaag gatattgtag
     8581 ataatttctt tggctttcca accaacttca catgggacaa ctttagccgt ctcttagctg
     8641 atgggattgg aggctattat tggaactctg tcgtcatcac tgtcttgtct ttacttgcag
     8701 taatgatctt tatccctatg gcagcctact ccatcgctcg caatatgagt aaaagaaaag
     8761 cctttaccat catgtatacc ctcttaatcc tcggaatctt cgtacctttc caagtcatca
     8821 tgattccgat tacggttatg atgagtaaac tcggtttggc taataccttt ggtttgatct
     8881 tgctctactt gacctatgcg attccacaga ccctctttct ctatgttggc tatatcaaaa
     8941 tctcgattcc agaaagtctg gatgaagcag cagagatcga tggggctaat caatttacaa
     9001 cctatttccg catcatcttc ccaatgatga aaccgatgca tgcgacaacc atgatcatca
     9061 atgccctttg gttctggaat gacttcatgt tgccactcct tgtcttgaac cgggattcca
     9121 aaatgtggac tctgcctttg ttccaataca actacgcagg ccaatatttc aacgactacg
     9181 gaccaagctt tgcctcttac gtggtcggca ttatcagtat caccattgtc tatctcttct
     9241 tccaacgcca tatcatttca ggaatgagca acggggcagt gaagtaatac tcaatgaaaa
     9301 tcaaagagca aactaggaag ctagccgcag gttgctcaaa acactgtttt gaggttgtgg
     9361 atgaaactga cgaagtcagt aaccatacct acggtaaggc gacgctgacg tggtttgaat
     9421 ttgattttcg aagagtataa catgaatttg atttacgaag ccagattata tgagacttgg
     9481 cttcaattag aaaaaggaga gtaatgatgc caattcaaaa taaaaccatg ttgattacct
     9541 attctgatag ccttggaaat aatcttaaag acttatatga taatttggaa gagcattttg
     9601 gagatgctat tggaggagtt caccttttac catttttccc atcaacaggt gatcgtggat
     9661 ttgcgccagt tgactacgac gaagtggact cagcttttgg tgattgggag gatgttaagc
     9721 gtttaggtga gagatattat cttatgtttg attttatgat taatcatatt tctcgtcaat
     9781 ccaagtatta taaggactat caagaaaaac atgaagccag tgaatttaaa gatctctttt
     9841 taaactggga taagttttgg ccagaaaacc gtccgacaca gtctgatgta gatttaattt
     9901 acaagcgtaa ggatcgtgca ccaaagcaag agattgtgtt tgaagatggt tcagtggaac
     9961 atttgtggaa tacttttggt gaggagcaga ttgatcttga tgtgaccaaa gaagtaacta
    10021 tggaatttat ccgtaagacc attcagcact tggcaagtaa tgggggtgat ttgattcgtc
    10081 tagatgcctt tgcttatgca gtgaagaaat tgtatactaa tgatttcttt gtggaaccag
    10141 atatttggga tttattggac aaagttcgag atatcgctgc tgagtatggg acagagcttt
    10201 tacctgagat tcatgaacac tattcgattc agtttaaaat agcagaccat gattactatg
    10261 tttatgattt tgctcttcca atggtgacac tttatactct ttacagttcc agaacagagc
    10321 gtttggctaa gtggttaaag atgagcccga tgaagcaatt tacgacgcta gatacccatg
    10381 atgggattgg agtagtagat gtcaaggata tcctgaccga tgaggagatt gactatgctt
    10441 caaatgaact ctataaggtt ggagccaatg tcaaacgtaa gtactctagt gccgagtata
    10501 acaacttaga tatctaccaa atcaattcaa cctactattc agcgcttgga gatgatgatg
    10561 tcaagtattt tctcgctcgt ctaattcaag cttttgcccc aggtattcct caggtttact
    10621 atgtgggtct attagcaggc aagaatgact tgaaattatt agaagaaact aaagaaggtc
    10681 gaaatattaa tcgtcattac tatagcaacg aggaaatagc aaaagaagtg caacgatctg
    10741 ttgtgaaggt ccttctcaat ctattttctt tccgtaaccg ttcagaagcc tttgatctag
    10801 aagggactac tgagatagag acaccaacag ctcagagcat tgtaatcaaa cgtcaaaata
    10861 aagataagtc cgtaacagca gtagcagaaa ttgatttgca aaatcagact tatcgggtaa
    10921 ttgagaatgg agttgaagta acattttgaa gccttgatat ggtggataaa atagggtttt
    10981 tattttggaa aacgtttcct ttgttttcaa attgctaaaa aagtggtaca atataggata
    11041 gcttactatt atctgaatca gctgatttgg agagaaagga ttcattttga aatcaatagg
    11101 ctttattgaa aagctgaagg ggttgtctag taaagagctg attttattgg gaattatcct
    11161 gagtatcttt ttaccctttt atctttttgt agttgtactc tgtttatata ttatcagttt
    11221 gatttttaca ggagacatga aaagtattct tcagaaaatg ggggagcatc cgatgctgct
    11281 tctttttctt agctatagta ctgttatatc cattcttgca caaaattgga tgggtcttgt
    11341 ggcttcagta ggaatgtttc tatttactat tttctttttg cactatcagt cgattttatc
    11401 ccataaattc tttcgattga ttttgcagtt cgtcttgttt ggtagtgtct tgtcagctgc
    11461 ttttgccagt ttagaacatt tccaaattgt gaagaaattt aactatgctt ttctttcacc
    11521 caatatgcag gtgtggcatc agaaccgggc agaagtgacc ttctttaatc ctaattatta
    11581 tggaattatt tgttgtttct gtattatgat tgctttctat ctgtttacaa cgaccaagtt
    11641 gaattggttg aaagtattct gtgtgattgc aggctttgtt aatctctttg gtttgaactt
    11701 tactcaaaat cgaactgcct ttcctgctat tatcgctgga gcaattatct atctctttac
    11761 gactattaaa aactggaagg ccttttggct tagtattggg gtcttcgcga ttggtttgag
    11821 tttcctcttt tctagtgatt tgggagttcg aatgggtact ttagactctt ctatggaaga
    11881 acgcatttct atctgggatg ctgggatggc cttgtttaag caaaatcctt tttggggtga
    11941 agggccattg acctatatgc actcttatcc tcggatacat gctccttatc atgaacatgc
    12001 ccacagtctt tatattgata cgattctgag ttacggaatt gtgggtacca ttttattagt
    12061 tttgtcttct gttgctcctg ttcgcttgat gatggatatg agtcaggagt cggggaaacg
    12121 tccgattatc ggcctttatc tatctttcct tacagtggtt gctgtgcacg gaatttttga
    12181 cttggctctc ttctggattc agtcaggctt tattttcttg ctagttatgt gcagtattcc
    12241 attggagcat cgaatgttgg tatcggacat gacggattaa gttttataag tttgaaatct
    12301 tctaccttgg gtaggagatt tttttatacg atgggcatgt cgtgcatctg aggtgtaagt
    12361 cctctgtagg gatccactgc cggtgaatac aatagcgctc cccaagcctg actatcgtga
    12421 ggtagcggat taaaatggtc tggggataga tcgttttaag tctgacgcag gaaataagaa
    12481 ttgtcagaga aagcaatagt gaaatcgtag gctatgaata gaaacgtgat agcgaggagc
    12541 atatagtgga taaggtagcg agaaatttta aagtataaaa gatagtctta atctatatat
    12601 gtaaatcaca aaagtaattg aattcggaat aaggttggtg tgaaaagaca tagtaaactg
    12661 aatcttgaat actagaatga tacttctaca atattgttat aatttaattt gaattccaaa
    12721 atcacattgt tccgtccgta tttcatttta ctgtatgtct tcctaaactc caaagtttct
    12781 gcgtcaaatt tcctattttc actgtagtct ttgacacttc gaacgacaat ttgaatcata
    12841 tattcaaaaa aaaatgaaaa atttgtgcca acaagcctaa atattctgaa aatttgtttg
    12901 atttttaatg gataatgtga tataatggtt gtcaatctat aattcacata aacagaggag
    12961 tagaaaatga aaaaaaatcg tgtatttgct acagcaggtc ttgttttatt agcagcaggt
    13021 gtacttgcag catgcagttc ttcaaaatca tctgactcat cagcccctaa agcttatggc
    13081 tatgtttata cagcagaccc agaaaccttg gactacctga tttcaagtaa aaatagtaca
    13141 acagtagtga cttcaaatgg gattgatggt ttattcacta acgataatta cggtaatctt
    13201 gctcctgcag ttgcagagga ttgggaagtc tctaaggatg gtttgaccta cacttataag
    13261 attcgtaaag gggttaaatg gtttacctct gatggagaag aatatgcaga ggtgacggct
    13321 aaagatttcg tgaacggttt aaaacacgca gcagataaaa aatcagaagc tatgtattta
    13381 gctgaaaatt cggttaaagg cttggcagat tatctatcag gaacttcaac agatttttca
    13441 acagttggtg tcaaggcggt tgatgattat acgttacaat acactttgaa ccagcctgaa
    13501 ccgttctgga actctaagtt gacctattct attttctggc ctctgaatga agaattcgaa
    13561 acatcaaaag gaagcgattt tgctaaacca acagatccga catccttgct ttataatggt
    13621 ccattcttgt tgaaagggtt gactgcaaaa tcttctgtag agtttgtaaa aaatgagcaa
    13681 tattgggata aagaaaatgt ccacctagat actatcaatc tagcttacta tgatggatca
    13741 gatcaggagt cgctagagcg taacttcact agtggagctt atagttatgc ccgtctttac
    13801 cctaccagct ccaactattc taaggttgca gaagaataca aggacaatat ctattacaca
    13861 caatcaggct ctgggattgc tggtctgggt gtgaatattg atcgccaaag ttacaactat
    13921 acttctaaaa ctacagattc agagaaagta gctactaaga aggcattgct taacaaagat
    13981 ttccgtcaag ccttgaattt tgctcttgat cgctcagctt actcagctca aatcaatggt
    14041 aaagatggag cagctttagc agttcgtaat ttatttgtaa aaccagactt tgtttcagct
    14101 ggtgagaaga cctttggtga tttagtcgct gctcaacttc ctgcttatgg tgatgagtgg
    14161 aaaggtgtga atttagctga tgggcaggat ggtttattca atgctgacaa ggccaaggca
    14221 gagtttgcga aagctaagaa agctttagaa gcagacggcg ttcagtttcc tattcatctg
    14281 gacgttccag tagaccaagc atcaaaaaac tacatatctc gtattcagtc ctttaaacaa
    14341 tctgtagaaa cagttcttgg tgttgaaaat gtcgttgttg atattcaaca aatgacaagt
    14401 gatgaattcc ttaatattac ttactatgct gccaatgctt catctgagga ttgggatgta
    14461 tcgggaggag tttcatgggg gccagactat caagacccat ctacttacct ggatatttta
    14521 aaaacaacta gcagtgaaac tacaaaaaca tatttaggat ttgataatcc aaatagccct
    14581 tcagtagttc aagttggttt gaaagaatac gataaattag ttgatgaagc tgccaaagag
    14641 acaagcgact tgaatgtccg ttatgaaaaa tatgcagcgg ctcaagcatg gttgacagat
    14701 agttcactct ttattcctgc tatggcttct tctggtgcag caccagtgct ttcacgaatt
    14761 gttccattta ctggagcttc tgcgcaaaca ggctctaagg ggtcagatgt ttacttcaaa
    14821 tatttgaaat tacaagataa agtggtgact aaggaagagt atgaaaaagc tcgtgaaaaa
    14881 tggttgaaag aaaaagctga atcaaatgag aaagctcaaa aagaattggc aagtcatgtg
    14941 aagtaaataa tttctaatag aactttctct ccatgaggag aaggttcttt tgggattttt
    15001 aaaggaaata atatgaaaaa atatattttt atgcgtgttt tgcggtcatt ggtttcgatt
    15061 ttcttagtaa cgactttgac ctacacgatt atctatacct tggttcctcg aaaattgatt
    15121 ttcaagcagg atcctaacta taataaaatt gcgacaacgg ctgataaacg tgataactat
    15181 gaaaatactg tgtttgagcg tatgggctac attgagtatt acgatactaa agagttgcaa
    15241 gaaaaggcaa gtagcatgga ttcttctgta acagtagaag caaatgcgac caataaagct
    15301 atttatgaaa agtacatcaa tcaattaggt catggttgga ctttgggaga atttactgaa
    15361 agtggtcaat tctatgctac tcgtgaaatt ccaatttttg aacgtgtttt tcacttctat
    15421 gctaacttga ttgacattga ccatacaaat aaaatccaag accctgaaaa tccagacttg
    15481 aaacgctacc ttcgttttga aaatgatcca gctatcggat ggtcattggt cggttcagga
    15541 actaaacata aatatctctt gtactttaac agtcagttcc catttgttca tcaaaacttt
    15601 gtgaacttga atttaggtga ctcttaccca acctatgcta atacaccagt tcttcaggtt
    15661 attactcaag gtcaaggaca aaccaaaact gcccaagttc agttcccaac aggtaagaaa
    15721 acgtcttctg taaatattta ctcaagaacc tacaagtcac ctagtcaggc tgactctcgt
    15781 gaagtagcta gctatgggaa agatgatcct tatacagcga ctgaaagtaa ttaccaatat
    15841 ccatctatga ttgtcagctc tgctattact ggtttgattg gtttggttct tgcctatgct
    15901 cttgccgtgc cacttggttc agccatggct cgtttcaaga acacttggat tgatagcctc
    15961 tcaacaggga ctttgacctt cttgcttgct cttccaacga ttgccttggt ttacatcgtt
    16021 cgattgattg gatcatctat tgcccttcca gattcattcc ctatcttggg agctggagat
    16081 tggcgttctt acgttttacc agcagtcatc cttggtttgt tgggtgctcc tgttacagcc
    16141 atttggattc gtcgttacat gattgacttg caatctcaag actttgttcg tttcgctcgt
    16201 gcaaaaggtt tgtctgaaaa agaaatttca aacaaacaca tctttaaaaa tgccatggtt
    16261 ccgctggttt caggaattcc tggtgccatt attggggtta tcggtggtgc aacccttact
    16321 gaaacagtct tcgccttccc aggtatgggt aaaatgttga ttgactctgt aaaagcatct
    16381 aataactcta tggtcgttgg tcttgtcttc atctttacat gtatttctat cttctcacgt
    16441 cttttgggag atatttggat gactattatt gacccacgta ttaaattgac tgagaaagga
    16501 ggcaaataat gtctacaatc gataaagaaa aatttcagtt tgtaaaacgt gacgattttg
    16561 cctctgaaac tattgatgcg ccagcatatt cttactggaa atcagtgttt aaacaattta
    16621 tgaagaaaaa atcaactgta gtcatgttgg gaatcttggt agccatcatt ttgataagtt
    16681 tcatctaccc aatgttttct aagtttgatt tcaatgatgt cagcaaggta aacgacttta
    16741 gtgttcgtta tatcaagcca aatgcggagc attggttcgg tactgacagt aacggtaaat
    16801 cgctctttga cggtgtctgg ttcggagctc gtaactccat cctcatttct gtgattgcga
    16861 cagtgattaa cgtggttatc ggtgtttttg tcggtggtat ttggggtatt tcaaaatcag
    16921 ttgaccgtgt catgatggaa gtttacaacg tcatctcaaa catcccacct cttttgattg
    16981 ttattgtctt gacttactca atcggagctg gattctggaa tctgattttt gccatgagcg
    17041 taacaacatg gattggtatt gccttcatga tccgtgtgca aatcttgcgc tatcgtgact
    17101 tggaatacaa cttggcgtca cgtactttgg gaacaccaac cttgaagatt gttgccaaaa
    17161 atatcatgcc tcaattggta tctgttattg tgacaaccat gactcaaatg cttccaagct
    17221 ttatctcata cgaagccttc ttgtctttct tcggtcttgg attaccgatt acagtgccaa
    17281 gtttgggtcg tttgatttcg gattattcac aaaacgtaac aaccaatgct tacttgttct
    17341 ggattccatt gacaaccctt gtcttggtat ccttgtccct tttcgtagtt ggtcaaaact
    17401 tagcggatgc tagtgatcca cgtacacata gataggagta gaaatgacaa aagaaaaaaa
    17461 tgtaattttg actgctcgcg atattgtcgt ggaatttgac gttcgtgaca aagtattgac
    17521 agccattcgc ggcgtttccc ttgaactagt cgaaggagaa gtattagcct tggtaggtga
    17581 gtcaggatca ggtaaatctg ttttgacaaa gaccttcaca ggtatgctcg aagaaaatgg
    17641 tcgtattgcc caaggtagta ttgactaccg tggtcaggac ttgacagctt tatcttctca
    17701 caaggattgg gaacaaattc gtggtgctaa gattgcgact atcttccagg acccaatgac
    17761 tagtttggac cccattaaaa caattggtag tcagattaca gaagttattg taaaacacca
    17821 aggaaaaaca gctaaagaag cgaaagaatt ggccattgac tacatgaata aggttggcat
    17881 tccagacgca gatagacgtt ttaatgaata cccattccaa tattctggag gaatgcgtca
    17941 acgtatcgtt attgcgattg cccttgcctg ccgacctgat gtcttgatct gtgatgagcc
    18001 aacaactgcc ttggatgtaa ctattcaagc tcagattatt gatttgctaa aatctttaca
    18061 aaacgagtat catttcacaa caatctttat tacccacgac cttggtgtgg tggcaagtat
    18121 tgcggataag gtagcggtta tgtatgcagg agaaatcgtt gagtatggaa cggttgagga
    18181 agtcttctat gacccttgcc atccatatac atggagtctc ttgtctagct tgcctcagct
    18241 tgctgatgat aaaggggatc tttactcaat cccaggaaca cctccgtcac tttatactga
    18301 cctgaaaggg gatgcttttg ccttgcgttc tgactacgca atgcagattg acttcgaaca
    18361 aaaagctcct caattctcag tatcagagac acattgggct aaaacttggc ttcttcatga
    18421 ggatgctcca aaagtagaaa aaccagctgt gattgcaaat ctccatgata agatccgtga
    18481 aaaaatggga tttgcccatc tggctgacta ggaggaagga aatgtctgaa aaattagtag
    18541 aaattaaaga tttagaaatt tccttcggtg aaggaagtaa gaagtttgtc gcggttaaaa
    18601 atgctaactt ctttatcaac aagggagaaa ctttctcgct tgtaggtgag tccggtagtg
    18661 ggaaaacaac tattggtcgt gctatcatcg gtctaaatga tacaagtaat ggagatatca
    18721 tttttgatgg tcaaaagatt aatggtaaga aatcgcgtga acaagctgcg gaattgattc
    18781 gtcgaatcca gatgattttc caagaccctg ccgcaagttt gaatgaacgt gcgactgttg
    18841 attatattat ttctgaaggt ctttacaatc accgtttatt taaggatgaa gaagaacgta
    18901 aagagaaagt tcaaaatatt atccgtgaag taggtcttct tgctgagcac ttgactcgtt
    18961 accctcatga attctcaggc ggtcaacgtc aacgtatcgg tattgcccgt gccttggtca
    19021 tgcaaccaga ctttgttatt gcagatgagc caatttcagc cttggacgtt tctgtacgtg
    19081 cccaagtctt gaacttgctc aaaaaattcc aaaaagagct cggcctgacc tatctcttca
    19141 tcgcccatga cttgtcggtt gttcgcttta tttcagatcg tatcgcagtt atttacaagg
    19201 gtgttattgt agaggttgca gaaacagaag aattgtttaa caatccaatt cacccatata
    19261 ctcaagcctt gctttcagcg gtaccaatcc cagatccaat cttggaacgt aagaaggtct
    19321 tgaaggttta cgatccaagt caacacgact atgagactga taagccatct atggtagaaa
    19381 tccgtccagg tcactatgtt tgggcgaacc aagccgaatt ggcacgttat caaaaaggac
    19441 taaactagta atggttttat aatttccatg tcaattttta tggaaattag gctctttgtc
    19501 aactgtagtg ggttgaagtc agctaagctc gagaaaggac aaatttcgtc ctttcttttt
    19561 tgatgttcaa agcgataaaa atccgttttt tgaagttttc aaagtttcga aaaccaaagg
    19621 cattgcgctt gataagtttg atgagattat tggtcgcttc cagtttggca ttagaatagt
    19681 gtagttgaag ggcgttgata atcttttctt tatctttgag gaaggtttta aagacagtct
    19741 gaaaaatagg atgaacctgc ttaagattgt cctcgataag ttcgaaaaat ttctctggtt
    19801 ccttattctg gaagtgaaaa agcaagagct gatagagctg atagtggtgt ttcaagtctt
    19861 ccgaataact caaaagcttg tttaaaatct ctttattggt taagtgcata cgaaaagtag
    19921 gacgataaaa acgtttatca ctcagtttac ggctatcctg ttgtatgagt ttccagtagc
    19981 gcttgatagc cttgtattca tgggattttc gatgaaactg attcatgatt tgaacacgca
    20041 cacgactcat agcacggcta agatgttgta caatgtgaaa gcgatcaaga acgattttag
    20101 cattcgggag tgaaacagtc taggagactg tttcagcctg agcctagaaa tttgaaagcg
    20161 aagctgttta gccaagtcat agtaagggct aaacatatcc atagtaatga ttttgacgcg
    20221 acatcggacg gctctatcat atttaagaaa gtgatctcgg atgacagctt gtgttctacc
    20281 ttcaagaaca gtgatgatat cgagcttttc aaaattttgc gcaataaagc tcatctccat
    20341 ctcccgattg aaacagtcac tccccggact gtttcaacgt cccaagacat aatcttaggc
    20401 agatttctaa aattacactc aaagtgaaag tcattgagct tgcgaatgac agttgaagtt
    20461 gaaatggcca gctgatgggc aatatcagtc atagaaatct tttcaattaa cttttgagca
    20521 atcttttggt tgatgatacg agggatttgg tgattcttct tgacgataga agtttcagcg
    20581 accatcattt ttgaacagtg atagcactta aagcgacgct ttctaaggag aattctagta
    20641 ggcataccag ttgtctcaag gtaaggaatt ttatagggtc tttaatgtct agtaattttg
    20701 tgataaaatg taattgttct atatgattct ttctaatgag ttgttttgtc gcttttcatt
    20761 ataggtcata tgggactttt tttctacaca aaaataggct ccataatatc tataggggat
    20821 ttacccacta caaatattat agagccgaaa aaggctgaga tctggtgtct cagtctttta
    20881 tttcttgcgt tttgcaaaat ctacaaatct aaatttttct aacttatggc gactttcggt
    20941 aaactgaaat tggcgtccgt cttggagata gacttttgat ttaatcgaaa cgacataagg
    21001 gtctttgcca atgtccatga gaatcttgtc tcggtcgctt gagtggtcaa tggtgatttc
    21061 cttctgagca taatcaataa ggagtttgag gccattttct atataagaat agatagactg
    21121 ctcagcaatt tggcgagtga gatttggaat tagttccata tccagatagt ctgtatccag
    21181 aacggatacc agatcatcca ccacacgctg gcggaccacc ttccaaacca tccgaaactc
    21241 tgggaaaccg gttatcagcg aggatttttt atcaataata atcttgtcca gactgaccac
    21301 gttggtttta gagcgcagtc caagttcttt aactagttct tggtagctgg ttaggttgga
    21361 tacagggaaa ttgacggttt cttctttgac gacttgagaa ccttgccctc ttatcttttt
    21421 gatcaatcct tcctcttgga ggagagacag ggcctttcgg acggtatcac gactcacttg
    21481 atattgctcc ataaggtcgt gctcgctagg aaggaaatct ccgacagcgt aagtctcgtt
    21541 ttgaatggtt tcttggattt gcttaaataa ttgttggtat ttcttcattt tgcctgctta
    21601 aataggtttt tagtctagtt taatgaacac ctgtatctat tttaccatac aagtgctaga
    21661 aaatttacaa aaaaacaccc tttttatacc aaacaagttg tagacaagtt tggtatcgtt
    21721 tacaatatac ttatcaaatc aaacttgctt tgacaagtat aaggagaatc aaatgggaaa
    21781 atttgaacaa gaagccaaag atctgcttca ggcaattgga ggcaaagaaa atgtgactgc
    21841 cgtaactcac tgtgcgacac ggatgcgctt tgttttaaga gatgataaga aggctaatgt
    21901 taaagctatc gagtcaattc cagctgttaa aggaactttt acaaatgcag gtcaatttca
    21961 ggtaatcatt ggaaatgacg tgcccatctt ttataatgat tttacagccg tttcaggtat
    22021 tgagggtgtt tccaaagaag caaccaagtc tgcagctaag agtaatcaaa acgtggttca
    22081 aggtgttatg accactctgg cggaaatctt tactccgatt attccagcct tgattgttgg
    22141 tggattgatc ctcggtttcc gtaatgtctt ggaaggtgtc cattggtcga tgttggatgg
    22201 caagaccatc acagaatcct ctcagttttg ggcaggggtt aatcacttcc tctggttgcc
    22261 tggtgaagct atcttccagt tcttaccagt agggattact tggtctgttt ctcgtaagat
    22321 gggaaccagc caaattttgg ggattgttct cggaatctgt ttggtatcgc ctcagttgct
    22381 caatgcctat gcggttgctt caacgccagc agctgatatc gcggcaaact gggtttggaa
    22441 ttttggttat tttactgtta atcgtattgg ttaccaagcc caagttatcc cagccttgct
    22501 tgcaggtttg agtctgtctt atcttgaaat tttctggcgc aaacatatcc cagaagtcat
    22561 ttccatgatt tttgtacctt tcttgtcatt gattccagcc ttgattttgg ctcatactgt
    22621 tttgggacca atcggttgga caattggaca aggactttca tcagttgtct tggcaggttt
    22681 aactggtcca gttaaatggc tcttcggtgc aatttttggt gccctctacg ctccatttgt
    22741 catcacaggt ctgcaccata tgaccaatgc cattgataca caattgattg cggatgctgg
    22801 tggcactgcc ctatggccaa tgattgctct ttctaatatt gctcaaggct cagccgtgtt
    22861 tgcctattat ttcatgcatc gccatgatga gcgtgaggct caggtttcac ttcctgcaac
    22921 catttcagcc tatctcggtg ttacagaacc agctcttttt ggggttaacg taaaatatat
    22981 ttatccattt gttgctggga tgactggttc agcccttgca ggcatgttat ccgttacttt
    23041 taatgtaact gcggcttcta ttggtatcgg tggtttgcca ggtattctct ctattcaacc
    23101 tcaatacatg ctgccatttg caggaactat gctagttgcg attgttgttc caatgctctt
    23161 gactttcttc ttccgcaagg ctggtctctt tacaaaaaca gagggcgata cgaacttgca
    23221 ggcagaattc gttgctcaag aagaagcaga atttgtgagc catgaactag tagaacttac
    23281 ttcggtagaa attatcagcc cactaactgg ccaagtgaaa gaattgagtc aagcgacgga
    23341 tcctgttttt gcatcaggtg tcatggggca aggtctggtc attgaaccaa gccaaggtga
    23401 gttgatctct ccagttaatg gaacagtgac ggttcttttc cctaccaagc atgccatcgg
    23461 cattgtctct gacgagggag ttgaattgct catccacatc ggtatggata cagtaggtct
    23521 tgatggcaaa ggttttgaaa gtcttgtagt ccaaggagat cacgttacag ttggtcagca
    23581 actgattcgt tttgatatgg atgtcattaa ggctgcaggt ctggtgacag aaactcctgt
    23641 tatcatcacc aaccaagatg cttatacagc gactattact ggaacttatc cgacaacgat
    23701 ccaagctgga gcatctctca tggtcgctac acgaatctaa tactcttcga aaatctcttc
    23761 aaaccacgtc agctctatct gcaacctcaa aatagtgttt tgagcaacct gtggctagct
    23821 tcctagtttg ttctttgatt ttcattgagt ataattgaaa tagcacaaat agggacggaa
    23881 tactgcttcc tcccttttat cagaaaagga gaaacagatg acacttgata aaggaaaagt
    23941 agtctatcaa atctatccaa aatcttacaa agacaccact gaaaacggta ttggggattt
    24001 ccgtgggatt atcgaaaaaa ttccctattt agccaaacta ggtgtggata tggtctggct
    24061 caatccattc tatccaagcc ctcaacggga taatggttac gatatttcag attatatggc
    24121 agtggatcct ctttttggtg atatggctga ttttgaggaa atggtgtgtg tcggtaaaga
    24181 gcacaagatt gactttatgc tggacatggt acttaatcat tgttcgacag agcatgaatg
    24241 gtttcagaaa gccctagctg gtgataagta ttatcaagac tttttcttca tccaagacca
    24301 accaacagat tggcagtcta agtttggtgg ttctgcatgg gcgcctttcg gggatactgg
    24361 gaaatactat cttcacctat ttgatgagac ccaggctgac cttaactggc gcaatcccaa
    24421 tgtccgtaag gagcttttca aggttgttaa tttctggcgc gacaagggtg tcaaaggttt
    24481 tcgatttgat gtgatcaatt tgatcggtaa ggacgaggtt tcagtggact gtcctgaaaa
    24541 tgaagggaag ccagcttata cagacaaacc tatcgttcat aactatttgc gtatgatgaa
    24601 ccaagccact tttggatctg acgatagctt tatgacagtt ggggaaatgt cttctaccac
    24661 catggaaaac tgtgtccttt attcgtcgcc tgatcgtcag gaattatcca tgacctttaa
    24721 ttttcatcac ctcaaggtgg actataagga tggacaaaag tggaccttgg ctccctttga
    24781 ttttgaagag ttgaagagtc tttaccatag ttggggtaag gaaatgagtg ataaagacgg
    24841 ttggagtgcc ctcttttgga acaatcacga tcaaccacgt gccttgaacc gttttgtcga
    24901 tattcaaaac ttccgcaagg aaggagccac catgctagca gccagcattc acctgtcacg
    24961 tgggacacct tatatctaca tgggtgagga aatcgggatg attgacccag actatgattc
    25021 tatggctgat tatgtggatg tcgaatcgct taatgcctat cagatgctct tagaagaagg
    25081 aaagagtcag caagaagcct tccagattat tcaagctaag tcgcgtgata attcacgcat
    25141 tcccatgcag tgggatgctt cggaaaatgc aggattttca acaggcactc catggttgaa
    25201 agctggtaaa tcctataaag atatcaatgt agaaaatgaa atcaaaggtc cgattttcac
    25261 cttctatcaa gacttgattc gactgcgtaa ggaaatgcca atcatttcag aaggaaatta
    25321 caaaccagcc tttgaagata gcaaacaagt ctacgctttt gaacgccagt ttgaggatca
    25381 aaagttacta gtgctcaata acttttatgc taaagaagtg gaaatcgact tgccagcagt
    25441 ctaccaaaat ggacagattt tgatatcaaa ctatgaagat gcagaagtgt ctgagaaaat
    25501 tctactcaaa ccctatcaaa cactggctat ttatgtaaat taatactctt cgaaaatctc
    25561 ttcaaaccgt gtcagtttta tctgcaacct caaagcggtg ctttgagcaa cctgtggcta
    25621 gcttcctagt ttgctctttg attttcattg agtataaact tagcaaggag acctcttttt
    25681 cagaaaagca gggttctttt tgctgtctat tccatccttg aaagtgtaga acaaactggt
    25741 cagggtggct agtttgtggt ataatgaaag ggattcaaaa agaaacagga gaaaaatgat
    25801 ggatttactt ttagcaattg tattgattgt gctagctttt ctaggaggag ctcttggagg
    25861 aatgtacttg gttcgtaagc aaatcgaaaa agaatttgct gacaacccac gtttgaatgc
    25921 tgaagcagtt cgtactcttt tgagtgcaaa tggtcaaaaa ccaagcgaag ctaaggtaca
    25981 acaagtttac caccaaatca tccgccaaca aaaggcagcc cttgctaaca ataaaaagaa
    26041 aaaataaata aggaaaagtc tgggatgaaa gttccagact tctcactatg ttggttatgg
    26101 tttagggatg agactttttc cttgcattct attgatattt gattatgatt aagagagagg
    26161 tagttgacat tctatcaagc tgtcggtcag ttcgttcagt acaaggaatc ataatgaacg
    26221 atcaatcaga aaaaagacta gaaagaagac tgtatggata atcgaccaat tggttttttg
    26281 gattcgggtg tcgggggctt gaccgttgtg cgcgagctca tgcgccagct tccccatgaa
    26341 gaaatcgtct atattggaga ttcggcgcgg gcgccctatg gcccccgtcc tgctgagcaa
    26401 attcgtgaat atacttggca gctggtcaac tttctcttga ccaaggatgt caaaatgatt
    26461 gtcattgctt gtaacactgc gactgcggtc gtctgggaag aaatcaaggc tcaactagat
    26521 attcctgtct tgggtgtaat tttgccagga gcttcggcag ccatcaagtc cagtcaaggt
    26581 gggaaaatcg gagtgattgg aacgcccatg acggtacaat cagacatata ccgtcagaaa
    26641 atccatgatc tggatcccga cttacaggtg gagagcttgg cctgtcccaa gtttgctccc
    26701 ttggttgagt caggtgccct gtcaaccagt gttaccaaga aggtggtcta tgaaaccctg
    26761 cgtcccttgg ttggaaaggt ggatagcctg attttgggct gtactcatta tccactcctt
    26821 cgccctatta tccaaaatat gatggggcca aaggttcagc tcatcgatag tggggcagag
    26881 tgcgtacggg atatctcagt cttactcaat tattttgaaa tcaatcgtgg tcgcgatgct
    26941 ggaccactcc atcaccgttt ttacacaaca gccagtagcc aaagttttgc acaaattggt
    27001 gaagaatggc tggaaaaaga gattcatgtg gagcatgtag aattatgaca aataaaattt
    27061 atgaatataa ggatgaccag gactggtatg ttgggtctta tagtattttt ggtggcgtta
    27121 acagtttgag cgactatcag acagattttc ctctgtttga attctccaaa atatttggag
    27181 atgaagagta tggtttcccg ctttcagtta ctgttttacg ctatggttct acctaccgtt
    27241 tgttctcctt tgtggtagat atgcttaatc aagaaatggg acgaaacttg gaagttattc
    27301 aacgtcatgg ggccctgctc ttggttgaaa atgggcaact cttgtatgta gaattgccta
    27361 aagaaggggt caatgttcat gatttctttg agacaagcaa ggtcagagaa accttgttga
    27421 ttgcgactcg taacgaaggc aaaaccaagg aattccgagc tatctttgat aagttaggct
    27481 acgatgtgga aaatcttaat gactaccctg acctgcctga agtagcagaa acaggtatga
    27541 cctttgaaga aaatgcccgc cttaaggcag aaaccatttc tcaattaacg ggcaagatgg
    27601 ttttggcaga tgattctggt ctcaaagtcg atgtccttgg tggcttacca ggcgtctggt
    27661 cagctcgttt cgcaggtgtg ggagcaactg accgtgaaaa taatgccaaa ctcttgcacg
    27721 aattggccat ggtctttgaa ctcaaggacc gctcggctca gttccacaca accctagtcg
    27781 tagccagccc aaataaggaa agtttagttg ttgaagcaga ctggtcaggt tatattaact
    27841 ttgaacctaa gggtgaaaat ggctttggct atgatcccct cttccttgta ggagagacag
    27901 gtgagtcatc agctgaatta accctggaag aaaaaaatag tcaatctcac cgtgccttag
    27961 ccgttaagaa acttttggag gtatttccat catggcaaag caaaccatca ttgtaatgag
    28021 cgattcccat ggcgatagct tgattgtgga agaagtccgt gatcgctatg tgggcaaagt
    28081 cgatgccgtt tttcataacg gcgattctga actacgtccg gattctccac tttgggaggg
    28141 catccgcgtt gttaaaggga acatggactt ctacgccggc tacccagaac gtctggtgac
    28201 tgagcttggt tcgaccaaga ttatccaaac tcatggtcac ttgtttgaca tcaatttcaa
    28261 ctttcaaaag ttggactact gggctcagga ggaagaggcc gctatctgcc tctatggtca
    28321 cttgcatgtg ccaagtgctt ggttggaagg caagatcctc tttctaaatc caggctctat
    28381 cagtcaacca cgaggtacca tcagagaatg tctctatgct cgtgtggaga ttgatgatag
    28441 ttacttcaaa gtggactttt tgacacgaga tcacgaggtg tatccaggtt tgtccaagga
    28501 gtttagccga tgattgccaa ggagtttgag actttcttgt tggggcagga ggaaactttt
    28561 ttgacccctg ctaaaaatct agctgtgttg attgatactc acaatgcgga tcatgcgacc
    28621 ctcttgctca gtcagatgac ctatacccgt gttcccgttg tgacagatga aaaacagttt
    28681 gttgggacga ttggactcag agatattatg gcttatcaga tggagcatga cttgagccaa
    28741 gaaatcatgg cggatacgga tatcgttcat atgacaaaaa cggacgtagc ggttgttttg
    28801 cctgatttca ccattacgga ggtcttgcac aagctagtag atgagtcctt cttaccggtt
    28861 gtggatgcag agggtatttt ccaagggatt attacgcgca agtccatcct caaggccgtt
    28921 aatgccctct tgcatgactt tagtaaggaa tatgagattc gatgccaatg agagacagga
    28981 tttcagcctt tttagaggaa aagcagggct tgtctgtcaa ttccaagcag tcctataagt
    29041 atgatttgga gcaattttta gacatggtag gtgagcggat ttctgagacc agtctcaaga
    29101 tttaccaagc ccagctagcc aatctaaaaa tcagcgccca gaagcgaaag atttcggcct
    29161 gtaaccaatt tctatacttt ctctatcaaa aaggagaggt ggacagcttt taccgcttgg
    29221 aattagccaa acaagctgaa aagaagacgg aaaagccaga gattctatac ctagactctt
    29281 tttggcagga aagcgaccat ccagagggcc gcttgctagc gctcttaatc ctagaaatgg
    29341 ggctcttgcc cagtgagatt ttagccatca aggttgcgga catcaatctg gattttcagg
    29401 tgttgcgaat cagcaaggct tcccaacgga ggattgtcac cattcccacg gccttgcttt
    29461 cagaattgga acccttgatg gggcagacct atctttttga aagaggaggg aaaccctatt
    29521 ctcgtcagtg ggcctttcgt cagttagaat cttttgtcaa ggagaaaggt tttccatcct
    29581 tatcagctca agtcttacgt gaacagttta ttctaagaca aatagaaaac aaggtcgatt
    29641 tgtacgaaat tgcaaaaaaa ttaggattaa aaacagtcct gaccttagaa aaatatagat
    29701 aatggatatt aaattaaaag attttgaagg acccctggac ttactcttgc atctggtttc
    29761 taagtaccag atggatatct acgatgtgcc cattacggaa gtcatcgaac agtatctagc
    29821 ctatgtttca accctgcagg ccatgcgtct ggaagtgacg ggtgagtaca tggtcatggc
    29881 tagtcagctc atgctgatta agagtcgtaa actccttccg aaggtagcag aagtgacaga
    29941 cttgggggat gacctggagc aggacctcct ctctcaaatc gaagaatatc gcaagttcaa
    30001 gctcttgggt gagcacttgg aagccaagca ccaagaacgg gcccagtatt attccaaagc
    30061 gccgacagag ttgatttacg aagatgcgga gcttgtgcat gacaagacga ccattgacct
    30121 ctttttggct ttttcaaata tactagccaa gaaaaaagag gagtttgcac aaaatcacac
    30181 gacgatcttg cgggatgagt ataagattga ggacatgatg attatcgtga aagagtcctt
    30241 gattggacga gatcaattgc gcttgcagga tttgttcaag gaagcccaga atgtccaaga
    30301 ggtcatcacc ctctttttgg caaccctaga gttaatcaaa acccaggagc tgatcctcgt
    30361 gcaagaggag agttttggag atatctatct catggaaaag aaggaagaaa gtcaagtgcc
    30421 tcaaagctag acttgataga gaggaaagat gagtacttta gcaaaaatag aagcgctctt
    30481 gtttgtagcg ggtgaagatg ggattcgggt ccgccagtta gctgaactcc tctctctgcc
    30541 accgacaggc atccagcaaa gtttaggaaa attagcccag aagtatgaaa aggacccaga
    30601 ttccagtttg gctttgattg agacaagtgg tgcttataga ttggtgacca agcctcaatt
    30661 tgcagagatt ttgaaggaat actctaaggc gcctatcaac cagagcttgt ctcgggctgc
    30721 ccttgagacc ttgtccatta ttgcctacaa acagccgatt acgcggatag aaattgatgc
    30781 catccgtggg gttaactcga gtggagcctt ggcaaagttg caggcttttg acctgataaa
    30841 ggaagacggg aaaaaggaag tattggggcg ccccaacctc tatgtgacta cggattattt
    30901 cctagattac atggggataa accatttaga agaattacca gtgattgatg agcttgagat
    30961 tcaagcccaa gaaagccaat tatttggtga aaggatagaa gaagatgaga atcaataagt
    31021 atattgctca cgcaggtgtg gccagtagga gaaaagcaga agagctgatt aagcaaggct
    31081 tggtgacggt taacggccaa gtggtgcgtg aactggcaac cactatcaag tcaggcgaca
    31141 aggtcgaagt tgaaggtcaa cctatctaca acgaagaaaa ggtctactat ctgcttaaca
    31201 aaccacgtgg tgtgatttcc agtgtgacag atgataaggg tcgcaagacg gttgtcgacc
    31261 tcttgcccaa tgtcaaagaa cgtatttacc ctgtgggtcg tttggactgg gatacatcag
    31321 gtgtcttgat tttgaccaat gatggggact ttacagacga gatgattcac cctcgtaatg
    31381 agattgacaa ggtttatgtc gcgcgtgtta aaggtgtggc caataaggac aatcttcgcc
    31441 ccttgacccg tggtcttgag attgatggta agaaaaccaa gccagctgtt tatgaaattc
    31501 tcaaagtgga cccagtcaaa aatcgctctg tggtgcagtt gaccatccat gaagggcgta
    31561 accatcaagt taaaaagatg tttgaagctg ttggtctcca agtagataag ttgtctcgga
    31621 ctcgtttcgg acacctagac ttgacaggac tccgtccagg agaatctcgt cgtcttaata
    31681 aaaaagaaat cagccaacta cacaccatgg ctgtaactaa gaaataatga aacgaatttt
    31741 aatagcgcct gtgcgctttt accaacgttt tatctcacca gtctttccac cctcttgtcg
    31801 ctttgatctg acttgttcca actacatgat tcaggctatt gaaaaacatg gttttaaggg
    31861 ggtattgatg ggcttggctc ggattttacg ttgtcatccc tggtcgaaaa caggtaagga
    31921 ccccgttcca gaccgctttt cccttaaacg aaatcaagaa ggggaatgag gttgggtaaa
    31981 tagatttcaa aatgataaaa acgcatccta tcaagtttga gtgaacttga taggatgcgt
    32041 tttagaatgt caaaatttta tactcttcga aaatctcttc aaaccgcgtc agctttcatc
    32101 tgcaacctca aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat
    32161 tttcattgag tattaaattg agtttgaagt ggcttatttc aaagcttttt gtatgtcttc
    32221 aatcatgagt tttgttgatt caagtccgcc tccgcttaga taccagaggt ctggtgttag
    32281 ttggataatc ttaccatttt tagcagcagg tgtttcagcg ataagggcat tttctaggac
    32341 accgtcgttg ctagagttgt ccccaccgat ggcaagggta cggttgatga caaagaggat
    32401 gtcagggttg atttctttga cactttcaaa gctgatttct tgtccgtggc gtgagtcttc
    32461 aaattttgta tcagttggtt tgaatttcaa ggtttggtac aagaaagaga aacgagattt
    32521 ggcaccaaag gctgccattt ttccttcatt aaggaggatc gcaagggctt ttttgtcaga
    32581 gctttcattt ttagtagcga cttcttggat gctcttgtct agcttggcca attcttcctt
    32641 ggctttctgt gtaccagttt cgccgaaggc acttgctaag gattcgatat tagccttggt
    32701 agaagtccag tagtcgtcct tgcttgcttg gaagagaacg gttggggcga tttctttgaa
    32761 tttgtctacg aatttttgtg tacgtggtga agcgataatc aaatcaggct caagggcggc
    32821 gatagcttct aaatcaggtt ctttcataga accaacattt ttgacagttc ccactaggtc
    32881 ttttagataa gtcggaacag tttttgtagg cattccgacg atattttttt caaatcctaa
    32941 agcgcgaata gtatccgcag cgccgaggtc aaaggtcaca atcttttcag gaactttgga
    33001 aagtttgacc tcgtccagtg aacttttaat ggttacctct gttggagcag agctactggt
    33061 ctctgtctga ctagtgcttg agtttgtact acatgcacca agtaggagca agaagctggc
    33121 cactagggca gtgaaataaa gtttaaggga tgttttcata atttctcctt tttaaaatgt
    33181 gataacgatt tagggagtct cttgatctta ttgactaaga gactgaaggt tctctaactt
    33241 gagcttttat gttactagct atagatacag atctttttgt cattgatatc agctagcgtg
    33301 atgggaatct cataaagttg actgagcagg tcagcctgca tgatttgatc ggttcttccc
    33361 ttgctaaaga cctggccgtc cttgaaggcg acaatttcat ctgcatactg actggccatg
    33421 ttgatatcgt ggaggacgat gataatggtc ttgccgagtt cctccaccag tcgtcgaaga
    33481 atctgcatca tgctgacgct ttgcttgata tcgagattgt tgagtggttc gtccagcaag
    33541 ataaagtccg tatcctgggc cagtaccata gcgataaaga cgcgctggag ttgcccccct
    33601 gacaggctat tgatgtagcg gtcttttaag ttggtcagtt ccaaatagtt cagagtttct
    33661 cggatttttt cccagtcttc tgatctaagt cgacctcggc tgtagggaaa acgtccaaaa
    33721 ctgaccagtt cttcaacagt caatttggct tggtaattga ttttctgttt taggatggtt
    33781 agttcttggg ccagttcttg cgaattccag ctatcgattt cacgtccttt gatactgaga
    33841 actccctgat ctttcttggt tagtctgctc atgatggaga ggagagtcga ttttccagca
    33901 ccatttggac caataaaggc tgtcagtttt tgaggactga cttcaagcga aatgccttgc
    33961 aaaatatcct gtttttgaat ggatttgtca atgttttcca gtttcactga cgagacctcc
    34021 tatatagtaa gataaagaat aagaagccac ccacactctc aatgatcata ctgatacgaa
    34081 tttccagtgc aaagactcgt tcaatcaagg cttgccccaa ggttaagcta ataaatccaa
    34141 tcagaatggc cactataaag agtaacttgt gctgatagtc tttgacaatc aggtaggtga
    34201 ggttggccag cataaagccg aagaaggcca taggtcctac caaggcagtg gccgttgagg
    34261 tcaaaagcac gattccccag aggagctctt tctgttcttt ttcaacatcg agtcccaata
    34321 tctgagccgt ttctctttgc aggtgcaaga catctagaac gactgctttt cgaaagaaaa
    34381 agattgtcaa agcgaggatg atcagagaac cgatggctag gatggaagtg ttgagatgtt
    34441 gaaaggaggc aaaaagacta ttttgcagtt tatcgtattc gtttggatcc attaggactt
    34501 gaaggaaggt gctgatattt cgaaagagac ttctgagcgc tagacagatc agcaggatga
    34561 agaccaggtc ttgcttcatc agtgtcttca agtaaccttg taaggcgaga aagaagaggg
    34621 actggacaag aagtaagact aggaattcta agatagggga tttgccaagt tgaagaaact
    34681 tgctttcaaa aaccagtagt agggtttgta gtaggacgta gaaggattca attcccaaaa
    34741 tactaggcgt caggaagcga ttttccgtca gggtttgaaa actaatggtc gaaatcccag
    34801 tcgcgatggc taccaagaga taaacgatga tcttttggga acgcaacttc caagcaaagg
    34861 ctgacaagtg agtgatgggc caaaagtaga gaagacaagc tccgatggca agaataatga
    34921 gaatccagaa gagcttggta tgtttgcttt tagtctgcat cttttcgtcc ccctctccag
    34981 agaagtagga taaagacgag actaccgatg attcctagca agagactgac agacaactca
    35041 tagggcctaa tcagaactcg ggataggata tcgcaagcca gaactagatt ggcaccaacc
    35101 agtgcgacca tgagtttggt ttgacttaga ttatctccat agcacttgcg aacaagattg
    35161 ggaacgataa ctccgagaaa tggtaggcca cccacggtaa tcatggtgac gcttgtcgtt
    35221 agcgccacca gaaagagggc cagtttttca agtagggagt aggaaatccc caaactctcg
    35281 ctggtttctt tccctagatt catgatggtg aaggtttggg ataatttcca aacggttatc
    35341 aggatgatga ggcctaagaa gagccactca tactgatggg tctgaatcat ggagaaggag
    35401 ccctgggtcc aggcagtcat actctgaacc agattgaaac gataggcgat aacttctgtg
    35461 actgagccga taatcccgct atagatgatc ccaatcagag gcaacatcca cctttccttt
    35521 acagtaaaaa tggtcataaa ggctaggaag aagagggtga atacgatgga tgaaacaaaa
    35581 gcgaagagca tcttttgggt cagactagcc gatggaaaga caaaaaggct cagcaccatt
    35641 cccagtttgg cggcttcagt cgttccaact gtactcggtg cagcaaactg attttgggta
    35701 atagtctgca tgagaaggcc tgccatactc atactagagg cagtcaggag aatactgata
    35761 gttcttggga gacgggactc ttgaaagagg agccaggtct gctggtcgaa atcaaatagc
    35821 tttccccatg aaaaatcact ggtcccaatg ctaatagaga gaaagactag gagtagaagt
    35881 aagccaatta aataatgaga aagtttcata ccccgtcctt tcatgtagat ttggtatcga
    35941 aagatatctg cggatataaa tgtaacatta tttttctaat ctgtcaataa aatttctgac
    36001 aatttaataa atacaacaag gagagagcaa caagactttc tcctttgtta tcctattcta
    36061 aaatgttttt accttaatct gataaaataa tatcttcgag ggagtagcta gccgtccaat
    36121 caagatattg tttagctttt gaagcatctg ctaggacact ggctgggtca ctagcacgtc
    36181 gagcaacaat ctcgtgtggg attttttaat ttagtaattc ttcagcagtt ttaaagattt
    36241 ctttgatagt atagcctttt ttagttccta agttaaagat ttgagaagaa ctgtcttctt
    36301 gaaataggta gttcattcct ttaacatgag cctatgcaag gtccaagaca taaatgtaat
    36361 ctcgaataca tgaaccgtca tgtgtatcgt agtcatctcc aaatgttttt aagctatcat
    36421 tttgtcccaa tgcggtcttg ttgatatttg gaatgatgtg agttggattt ttcacacgca
    36481 gaccgtttga agcatccatt tcagccccag caacattaaa gtaacggaaa ataacatatt
    36541 tccagtcgta gcgattggcc atccagtaaa tcattcgttc gcccatcagt tttgtctctg
    36601 cataagggtt gacagggtcg agcagggtat cttcagtcac cggcttgtca atacagttat
    36661 ttccatagag agaagcagtc gaagagaaca tgattttttg aatgccaact tcagataaga
    36721 ctttgagaac ttggttcata ccagcaacgt tggcagtgaa gtatttactt ggattttcaa
    36781 tactttcgct cacaacaatt tcacctgcac aatggaggac agcatcaatc tgattttctt
    36841 ctaagtaaac cttcaaggcg ctagcatcat aaacatccag ttctttaaag ctagcacgac
    36901 tatccacagc cgctcgattt cctgtggaga gattatcgag gacatgcacc ttatagccag
    36961 catttaaaag agctttaacg gtatgggagc caatgtagct agtcccacct gtaacaagaa
    37021 ttgttttggt catgattttt tccttttcta gttttgtact atagtaaatt gaaataagat
    37081 atgaacaact ctattaggaa agtcaaatta atttctagaa atgttttagc agctacagcg
    37141 tactattcca aactcaacca actatatatt taaagaaaga agaaagggaa gccaactatt
    37201 ttctgtaaat ttcatgaaaa atccaaacaa ctttgatggt gtattgtttt ttgtttggaa
    37261 ataaatattc gagttaattt tggaatgttt actagatttt gcactacatg caagagaata
    37321 ctatcctttt ctaagataga gcaggactaa gatactaact tagaaatcca ccttcccact
    37381 atccttctcc tataaaaagt ggtaaaatgg atgaaagaaa gaaggaactg aaatgacaac
    37441 attattttca aaaattaaag aagtaacaga acttgctgca gtctcaggtc atgaagcgcc
    37501 tgtccgtgct tatcttcgtg aaaagttgac accgcatgtg gatgaagtgg tgacagatgg
    37561 cttgggtggt atttttggta tcaaacattc agaagctgtg gatgcaccgc gcgtcttggt
    37621 cgcttctcat atggacgaag ttggttttat ggtcagcgaa atcaagccag atggtacctt
    37681 ccgtgtcgta gaaatcggtg gctggaaccc catggtggtt agcagccaac gtttcaaact
    37741 cttgactcgt gatggtcatg aaattcctgt gatttcaggt tctgttcctc cgcatttgac
    37801 gcgtggaaag gggggaccaa ccatgccagc cattgccgat atcgtttttg atggtggttt
    37861 tgcggacaag gctgaggcag aaagttttgg catccgtcct ggtgatacca tcgtaccaga
    37921 tagttctgca attttgacag ccaatgaaaa aaatatcatc tcaaaagctt gggataaccg
    37981 ctacggtgtc ctcatggtaa gcgagctagc tgaagcttta tcaggtcaaa aactcggcaa
    38041 tgaactctat ctgggttcta acgtccaaga agaagttggt ctgcgtggcg ctcatacctc
    38101 tacaaccaag tttgacccag aagtcttcct cgcagttgat tgctcaccag caggtgatgt
    38161 ctacggtggt caaggcaaga ttggagatgg aaccttgatt cgtttctatg atccaggtca
    38221 cttgcttctt ccagggatga aggatttcct tttgacaacg gctgaagaag ctggtatcaa
    38281 gtaccaatac tactgtggta aaggcggaac agatgcaggt gcagctcatc tgaaaaatgg
    38341 tggtgtccca tcaacaacta tcggtgtctg cgctcgttat atccattctc accaaaccct
    38401 ctatgcaatg gatgacttcc tagaagcgca agctttctta caagccttgg tgaagaaatt
    38461 ggatcgttca acggttgatt tgattaaaca ttattaaacc ataagggagg tggtagggat
    38521 ggtagaacca aacctagaaa gccttataaa agatctttac aatcatgctc gacatgattt
    38581 gagtgaagat ttagttgctg ctctcctaga gactactaaa aaactgccta ctacaaatga
    38641 gcaattgcag gcagttcgtc tctcaggcct ggtcaatcgt gaattgctcc taaatcccaa
    38701 acatccagca cctgagttgc tcaacttggc tcgctttatc aaaagagaag aagccaagta
    38761 cagaggaact gcgacttctg cgcttatgta tgaggaactc tttaaaatgc tttgattcca
    38821 ttgtggatca aagcattttt tgtaagatct atctcgtgag cgttcaaata gtagtaacaa
    38881 ggaatcatga gaagtcagcc gagcccatag tagtgaagaa acttctgtaa tggaagtgga
    38941 gcgaagtgag gaatcgtcaa acggtagggg ataggctgtt tgaagggtgc tacgaaaaag
    39001 atagggtaag gtgaaattat agcgggatga aataagatat gaacaaattg attaggaaaa
    39061 tcaaatgaat ttatagaaat cttttagcag tcatggcgtc ctattctagt ttcaaaatgc
    39121 tataaatacg aacaaattga ttgggaaatt caaatcgctt tctatcaatg ttttagaaga
    39181 tacagtgctc tagtctaact tcaatatact
//
LOCUS       DAVLGK010000017        38525 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLGK010000017 DAVLGK010000000
VERSION     DAVLGK010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38525
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.017"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(177..1274)
                     /locus_tag="VXE01_000964"
     CDS             complement(177..1274)
                     /locus_tag="VXE01_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV0749886.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRTQMALENGADLVVELPFLVSVQAADFFGQGAMDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(1284..2030)
                     /locus_tag="VXE01_000965"
     CDS             complement(1284..2030)
                     /locus_tag="VXE01_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0749887.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(2133..2486)
                     /gene="rsfS"
                     /locus_tag="VXE01_000966"
     CDS             complement(2133..2486)
                     /gene="rsfS"
                     /locus_tag="VXE01_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV0749888.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(2499..2999)
                     /locus_tag="VXE01_000967"
     CDS             complement(2499..2999)
                     /locus_tag="VXE01_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0749889.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(3000..3593)
                     /gene="yqeK"
                     /locus_tag="VXE01_000968"
     CDS             complement(3000..3593)
                     /gene="yqeK"
                     /locus_tag="VXE01_000968"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV0749890.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(3593..4222)
                     /locus_tag="VXE01_000969"
     CDS             complement(3593..4222)
                     /locus_tag="VXE01_000969"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV0749891.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRAFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(4274..4585)
                     /gene="yhbY"
                     /locus_tag="VXE01_000970"
     CDS             complement(4274..4585)
                     /gene="yhbY"
                     /locus_tag="VXE01_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV0749892.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(4799..5905)
                     /gene="yqeH"
                     /locus_tag="VXE01_000971"
     CDS             complement(4799..5905)
                     /gene="yqeH"
                     /locus_tag="VXE01_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV0749893.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            complement(5908..6498)
                     /locus_tag="VXE01_000972"
     CDS             complement(5908..6498)
                     /locus_tag="VXE01_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV0749894.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(6450..7358)
                     /locus_tag="VXE01_000973"
     CDS             complement(6450..7358)
                     /locus_tag="VXE01_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0749895.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNFFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(7415..7975)
                     /locus_tag="VXE01_000974"
     CDS             complement(7415..7975)
                     /locus_tag="VXE01_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEV0749896.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQVLHFVPNRNITVVSNFSRTD"
     gene            8114..9323
                     /gene="sstT"
                     /locus_tag="VXE01_000975"
                     /pseudo
     CDS             8114..9323
                     /gene="sstT"
                     /locus_tag="VXE01_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            9391..10344
                     /locus_tag="VXE01_000976"
     CDS             9391..10344
                     /locus_tag="VXE01_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0749897.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            10488..10868
                     /locus_tag="VXE01_000977"
     CDS             10488..10868
                     /locus_tag="VXE01_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0749898.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            10967..11188
                     /locus_tag="VXE01_000978"
     CDS             10967..11188
                     /locus_tag="VXE01_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0749899.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            11205..11519
                     /gene="trxA"
                     /locus_tag="VXE01_000979"
     CDS             11205..11519
                     /gene="trxA"
                     /locus_tag="VXE01_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0749900.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            11825..12358
                     /gene="queF"
                     /locus_tag="VXE01_000980"
     CDS             11825..12358
                     /gene="queF"
                     /locus_tag="VXE01_000980"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV0749901.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQHHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            12408..12587
                     /locus_tag="VXE01_000981"
     CDS             12408..12587
                     /locus_tag="VXE01_000981"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749902.1"
                     /translation="MLKAVFEVVDKTDEVSLKHCFEVADRTDEVSNHTYDKVKLTWFE
                     EIFEEYHTKKPCSSR"
     gene            complement(12612..13280)
                     /locus_tag="VXE01_000982"
     CDS             complement(12612..13280)
                     /locus_tag="VXE01_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV0749903.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(13391..14182)
                     /locus_tag="VXE01_000983"
     CDS             complement(13391..14182)
                     /locus_tag="VXE01_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV0749904.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLIFTSF
                     AKGIQEELFIQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLSADANQ
                     QSVFYQGLQSEIRDDLSNQGLHYLSKEKDTTGFSSQYGWVHSFAHGADLLTEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFSKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(14607..15371)
                     /locus_tag="VXE01_000984"
     CDS             complement(14607..15371)
                     /locus_tag="VXE01_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0749905.1"
                     /translation="MFKLSFQSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TSDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            complement(15364..16014)
                     /locus_tag="VXE01_000985"
     CDS             complement(15364..16014)
                     /locus_tag="VXE01_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749906.1"
                     /translation="MGILGINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSK
                     SCLGIVGQEDMLDMTLNVYDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVN
                     QLSSGMRRRLVLARALINRPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITS
                     HYMNEIEYLTDRVLMLHQGTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
     gene            16381..17058
                     /locus_tag="VXE01_000986"
     CDS             16381..17058
                     /locus_tag="VXE01_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0749907.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            complement(17118..18914)
                     /gene="pepF"
                     /locus_tag="VXE01_000987"
     CDS             complement(17118..18914)
                     /gene="pepF"
                     /locus_tag="VXE01_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0749908.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(18925..19668)
                     /locus_tag="VXE01_000988"
     CDS             complement(18925..19668)
                     /locus_tag="VXE01_000988"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV0749909.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(19670..20620)
                     /locus_tag="VXE01_000989"
     CDS             complement(19670..20620)
                     /locus_tag="VXE01_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV0749910.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSLDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            complement(20633..21652)
                     /locus_tag="VXE01_000990"
     CDS             complement(20633..21652)
                     /locus_tag="VXE01_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0749911.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYRDFYEFQNKVYISRTENEEKYSN
                     FIYESLFSDKVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEVVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDNMRTSLPVINQPAIDKKYNENLYQHDIVNILTLNYT
                     NVIDKLYNESAKSFSNQLRTNNYKFHIAPPIHAHGTVDICTVLGVSDETQISNSFDEE
                     QKESLIKNLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDGYIWNQIAEQSIRSS
                     VPVIIYHYVPHFDAGNPTRVKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIF
                     NLMER"
     gene            complement(21703..23886)
                     /locus_tag="VXE01_000991"
     CDS             complement(21703..23886)
                     /locus_tag="VXE01_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEV0749912.1"
                     /translation="MGPITIPKKTIITLEHLKYLHFSLEETKTYWEKNNIIDGILISI
                     YYNRIVAKSNRINGYFNVGGGNPFPNDTIVGAKFNDEKTKHIVTHYISRDALNKTITV
                     LSKIIEVFEEHFDRAITCEMFSDSSTFASINFSEYGISKSKFQQYLRDSCFIENFGVE
                     HTTVSDIQNSIVTFYDVHTDIFRLLNKLNIDISEANIMNQTTVLLDEKNIELLLSKAP
                     YLVSMIVEDFSKLSVDDFSLDNNDLKINLPSPMNEPVVGVIDTLFDKRVYFNEWVEYH
                     DFVSPDISKDSQDYKHGTAVTSLIVDGANLNPNLDDGCGNFRVRHFGVSLQSGFNSFT
                     IIKQIKEIVSQNADIKVWNLSLGSNDEIRENFISAEGALLDEIQFENDVIFIIAGTNA
                     SVINGKRKRIGAPADSLNSIIVNSVDFNNQSVSYSREGIVLSFFVKPDVSYYGGGNGD
                     FINVCEPLGLGRVAGTSFAAPFIARKMAYLIHIMGLSREEAKALLIDAAIPWNDKKTF
                     TDLSLIGNGIVPIKMDDILSTPDDEIKFIVSDISRAYDTYNYDFPVPISSESYPYVAK
                     ATMCYFPNCSRKQGVDYTNTEMQLTFGRLKSDGIKSINKDNQHAEDSPGYVRENAARN
                     IFRKWDNVKHIGESFTSRKRAKAILNPSNPQWGMSIKTIERLKSGDGQGVRFGVVVTL
                     KELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSLNEEIEFE"
     gene            complement(23948..24982)
                     /locus_tag="VXE01_000992"
     CDS             complement(23948..24982)
                     /locus_tag="VXE01_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0749913.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGVSK
                     SSVSRELSED"
     gene            complement(25092..25250)
                     /locus_tag="VXE01_000993"
     CDS             complement(25092..25250)
                     /locus_tag="VXE01_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEV0749914.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     KSVRENLI"
     gene            complement(25231..26319)
                     /locus_tag="VXE01_000994"
     CDS             complement(25231..26319)
                     /locus_tag="VXE01_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV0749915.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVRKDVVQTHKAMKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(26338..26808)
                     /locus_tag="VXE01_000995"
     CDS             complement(26338..26808)
                     /locus_tag="VXE01_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV0749916.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(27099..27551)
                     /locus_tag="VXE01_000996"
     CDS             complement(27099..27551)
                     /locus_tag="VXE01_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV0749917.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(27588..27761)
                     /locus_tag="VXE01_000997"
     CDS             complement(27588..27761)
                     /locus_tag="VXE01_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV0749918.1"
                     /translation="MTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGELN
                     KYTERGIGKQAGL"
     gene            complement(27904..28083)
                     /locus_tag="VXE01_000998"
     CDS             complement(27904..28083)
                     /locus_tag="VXE01_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749919.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(28248..28487)
                     /locus_tag="VXE01_000999"
     CDS             complement(28248..28487)
                     /locus_tag="VXE01_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749920.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            28757..30028
                     /locus_tag="VXE01_001000"
     CDS             28757..30028
                     /locus_tag="VXE01_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV0749921.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            30293..30365
                     /locus_tag="VXE01_001001"
     tRNA            30293..30365
                     /locus_tag="VXE01_001001"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30326..30328,aa:Lys,seq:ctt)
     gene            complement(30573..31892)
                     /locus_tag="VXE01_001002"
     CDS             complement(30573..31892)
                     /locus_tag="VXE01_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0749922.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVVTGTDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHMDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(31902..33518)
                     /locus_tag="VXE01_001003"
     CDS             complement(31902..33518)
                     /locus_tag="VXE01_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0749923.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFTFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            complement(33547..34437)
                     /locus_tag="VXE01_001004"
     CDS             complement(33547..34437)
                     /locus_tag="VXE01_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0749924.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            complement(34448..35365)
                     /locus_tag="VXE01_001005"
     CDS             complement(34448..35365)
                     /locus_tag="VXE01_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0749925.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            complement(35515..36516)
                     /locus_tag="VXE01_001006"
     CDS             complement(35515..36516)
                     /locus_tag="VXE01_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0749926.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            complement(36877..38358)
                     /locus_tag="VXE01_001007"
     CDS             complement(36877..38358)
                     /locus_tag="VXE01_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0749927.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKEISHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
BASE COUNT        11591 a         8337 c         6708 g        11889 t
ORIGIN      
        1 ataccacaaa ataacaagca taaagcggat tcaaagataa agattaaggt tcatatacta
       61 attttcttta ttgacttttt gtcttctgta ttagggagtt tatcattttc caaaaacttt
      121 atcttcaatt tgttatctaa aatttctaca ataaaaaagc ctacctttcg gtagacttag
      181 tttgtttcta ttctaatcgg cactcttcca aaattttgct ctgctatact tggctttcct
      241 agttggtaaa tctggtcaac cttttgagtc atagcatccc aaggttcttt gccaattcgg
      301 ctgactagat tgacctgtcc tttcagagac ttgagatgtt gcctgccttt ttcagtaaat
      361 ccaaggacat gaatggcttc tggcaagaca ttttctctag cctgcaccaa aatataggtc
      421 aataggcgtc tgacacgcgc cttggtgtaa cgtttggtag tcactaactc gaccaattct
      481 tccacagact gggctgtttt aatagcttct ttaatgcgca cagccatttc ttgattgacc
      541 tgatagatgg tggttaggtc gggatttgac aagatttgat agcggagcaa gggaaaatag
      601 tcttcccaga tcaccttact ggcctgctca aatagggcaa cagaaggcat aaaacgttct
      661 aagaaatctt ggtccttctg atgttgacgg agggctgtcg ccgaggcaaa gtccacatct
      721 ttattcacag aatggtaacc tgccccctga cgctgaatcg gatgcagctt gatatttcgt
      781 cctgcaaccg ccttggcata ggccagagca agaacatgat tgggggtatt acctgaaaaa
      841 tcaagaccag caaattcctt ccacatagct tgggttttct ggggatagga aagggaatca
      901 ggcagatttt ccacaaattt ctccatctca gcacctttct ctgtgtataa gtcagcaatt
      961 ttctgataat ctcgaacttc ctctgtccca aaaactagac tatcaatgcc caagcgatcc
     1021 aagatatcca tagctccttg accaaagaaa tcagctgcct gaacactgac taaaaagggc
     1081 aattccacta ccaagtctgc gccattttcc agcgccatct gggtccttgt ccacttatcc
     1141 acaatagcag gctctccacg ctgcatgaaa ttccctgaca tggcaacaat tttcagtccc
     1201 tctgcctgat ccagcaggta tttatggcca ttatgaaaag gattgaactc cgcgataata
     1261 cctgttatgg tcatgctaat ctcctacttc tgcgccacaa aaaaccaacg ggtgctagtt
     1321 tctgttggct ccttatcctc aaagtctgca tagagtttga aggacttaaa tccagcctgt
     1381 tccagcaaga tatcataggt caagatctca taggtcctct cctcatgtac ttcatcgtgg
     1441 cgactaaagg aaccgtcagc ctccttgata aagaaagtca gctcatgcac gatggagtga
     1501 ggagcttcgt cctcatatgt atcccaaagc atggcaaaat cttccgcatt ttcatggtag
     1561 gaatagccag ggaatacttc atctgtctgg taggtcgagt gcacgtcaaa gatgaaaact
     1621 ccctcttcat tcagcgcatt gtacacgtcc ttaaagacgt cccctacttc cacctcatcc
     1681 tgcatatagc agatagagtc cgaataacac gtgacaaaat cgtatttccc tgccttggac
     1741 aaattcagca tattaccttc tataaaagca atcttttgct tggctgaagt tgctctcttc
     1801 tccgcaatct tcaacatatc cgcactcaag tcaagtccag tcacatcaaa accagcctga
     1861 gagaagcgca ctgattgaat tcctgtccca caagccaatt ccaagagttt ctttctctcc
     1921 ttggtcttag gcaaatgacg cagagaaaaa ttcgtccatt tgtcgtataa actatcgtcc
     1981 atgaccgcat catagaccgc cgcaaaggtt tcataagtcg ccataatcat gatactaaga
     2041 gctccatggt aaacaccact agccctttac ctttctatca atttttctaa aataagcaaa
     2101 gaaacccagt tgactacaac tgagttcatc ttctaagcaa gagcttctga aatatctact
     2161 gaattcgcct catgccatag cttctctaga ttataatggg cacgcatttc ttctgaaaag
     2221 atatgcacga caacagcacc gaggtccagt aagacccagc ctccagctgc atcgccttcg
     2281 acatggctac ctttaaagcc tgcttgagct actttttcac ggatattagc tgcgatagcg
     2341 tccaactgac ggctattcat tgagctagtg atgacaaagt agtccgtcac actagtcaaa
     2401 tcttgtacat caagtgcgag gatatcctcc gcacgtttct catcagccgc tttcacgact
     2461 agttctagta attctttttc gttcatttaa tcctcttttt agaaaatatg tttgtaatct
     2521 aggacatctg caaagcgctc ctcccaaatg tcctcataaa attcattaat cgtttctgct
     2581 ggaatgtcat ccccatcaaa ggttgtgaca gcaccttctg gaacaataag ctgatagcca
     2641 tattcaaagg caaccttgac agaggtatcc acacaatatt ctgtctgcat accacataaa
     2701 actaattttt caatcccctg tttatccaag tattctttta agccagtttc tttgaaaata
     2761 ctgttatact tcttctgaaa gaccttttca gcaggttttc gatttaaaag cgcagataac
     2821 tgccaatctt ctgatgtttg agcttcagag ttctcaatat gttgaacata gataatttca
     2881 atattcttgc ttctagcctg gttttgtaaa taagaaattt tttccaatag actttttgtc
     2941 tggaacccag tttctactaa aacattctga acatcaatga ttataaaagc cgtcttcatt
     3001 tagtcctctt tcaaatagtg cacaaaggcg ttataggttt caagggtttg gggatagatg
     3061 gggaatccct gatgagctag atactccacg gtacgagctg tttcgtaggc caccgcctta
     3121 ttgagcgata gacttgcaat ctcacgcgcc acatctactc caggaaaggc tcgattgtgc
     3181 tcgatatagt ctgcgacgta gatgacctta tctaggtctg tcatttgacc agcaccgact
     3241 gtatggactt caatggctcg caggatttct gaatcatgca aatccaaatc ttcctgaatt
     3301 ttgtaaattc cgaccatacc atgccagaca ttattgcccc agtttttgag gtcagggtct
     3361 agctggtaac ggtcaatcaa gtctagaaat tcctgatctg acaacttttt agcatagtca
     3421 tgaagaagac ctgctagact tgctttctca acatctacac caaagcgctg agctaattcc
     3481 atagcggcac gctccacacc tagacaatgg gttagacgtt tctcaggtag aagctctgcc
     3541 attttttcca acaaagcctc acgggagcag ttgatatagt cttgatagga catcagtaga
     3601 gcccctcctt ctcgatgtag tctagcactg gctgaggtag gagaaagttg ggtttccgac
     3661 cttgggcaag gaaggcacgc accatgctgg acgagatatc catgagcggt acgtccaccc
     3721 agataactgg ataggaagtc cctaccttgt agcgtggacg ctgaaccccc acaaactgaa
     3781 ccatgtcaac cagttcatca attcggtacc acttaggcag atagtcaacc atgtcggcac
     3841 cgatgataaa gtaataatcc gtatctggat tcttctctgt caaaatcttc atggtgtcgt
     3901 aggtgtagga aatacccttg cgctccaact caatggtttc aatgactagg ccgtcaattc
     3961 cctcaattgc caactcaagc atcttgagac gatggtgttc agggatggtt tcctttttat
     4021 caacgtgagg aggttggtat tcaggcatga gcagaacttg atccagtccc aactgttgcc
     4081 gtacttgatc cgcaacaatg agatgggcat tgtgaacagg gttaaaattc ccccctaaaa
     4141 tcccaacttg tttgcgtttt ttctccttga tttctggctc caactctacc ttggtaaagg
     4201 gagtcaatag ttcgattgtc ataggctagt cccctttatt tctctataaa aacagttatt
     4261 tggagtttcg gtcttagatt tctttgactt tcttagaaat cttgcgattt tctttcttgc
     4321 tagattgttt aaacaaaatc aagatgcgtc ctattttttg gactgtatcc acaccgattt
     4381 cttcttccaa aatttcagct acttcgtgga tgttttcatc tgtgttttgt aagagagtaa
     4441 ccttgattaa ttcacgcgca tcaagagctt gacggacgct ggttttgatt tggtcgttga
     4501 gtccattttt cccgatttgg atgataggtt tgagggtgtg tgcctggctg ttgaggaagg
     4561 cacgttgttt tgatgttaat gacataattt tcttccttgt tttttgatag ttattttagg
     4621 tggtgaggga cggtcggaac taattttcca aagatttcat ctttgaaaaa tggatttcct
     4681 gacctcacaa ttgagccttg gtctcaattg tgccccttgc caatctacag attggcaatc
     4741 acaccacggc aataactatc gctatatgag ctcactttgt tcgctcagcg attttgtttt
     4801 aaataattgc ttttcgtgtg acgacggcga cgccttctgg tgcccagacg gcgacttttg
     4861 ctgtgcctgt tacacgaatc catcctaggc ctgagatgac taggtctgtc ttatctttaa
     4921 tggtaaagac atgctggact agccttggga aatcttcttt ttccttgcta tttggtggtg
     4981 tcaaaagagt tcccaggtgc ttatcgtaga aagcactagc tccttcaagc ttgctacgat
     5041 ggagtttgag ttcattatca aagaaagcag taaatccttg cttttctcct gctataaagt
     5101 caaagcgtcc caaaccacct aaaaataggg tttgctcagg attaagctga taggtcttag
     5161 gcttgatttc ctttttagga ctgacatact tgaggttttt ggccgtcaag tagtgagcca
     5221 tctggtggcg gtggataatt cccggcgtat cgtaaatata agatccgtcg tcaagcggaa
     5281 tctctatttt gtccaaggtt gtccctggga agcgtgaagt agtgatgaca ttctgatcac
     5341 ccgtgatttc ttggataata gcattgatta gagttgattt tccaacgttg gtcacaccga
     5401 ccacatagac atcgcggccc ttacggtagt gttcaatctt gtcaatgact tccttaatgg
     5461 catgtttatt ttgtgctgaa gttaggacca catcgactgg acgaagacct tcttcatggg
     5521 cacgtttcat gagccactgg ctaatcttac cagacttaac tgacttagga aggatatctt
     5581 ttttatttcc taccaagagg acatcattgc ccgagacgaa acgtggtaaa cctgggatga
     5641 cagatccatt aaaatcaaag atatcaatga cattgaccac taaagcatca ctgtctccca
     5701 cctcgtgcaa gagcttgagg aaatcatcgt tcgtcaactg gacatctgtg atttcattgt
     5761 agtggcggag acggaaacag cgttggcaat agacttcgcc agtctccaaa cctttttcaa
     5821 gtgccgactg gggggtaaaa ccaagaccag ctttatctgt cgtctgaatg gttgctccac
     5881 aaccaataca gagaatttct tccatagtta aattcctttt ttatatgtaa tcggtccgta
     5941 cttttcagtg atttttctca taacacgacg ctcacgagtt cggttaatct gcgttttgat
     6001 tgagtcatgt tggaccaagg gtttgactaa aattgaccga atccctgcac ggtgggctgc
     6061 tcgtatatct gtcatgagct ggtcaccaac catgaccact tcctttttgt catagtggaa
     6121 ttccttcata gcacggtcaa taccaaatgt gaagggcttc aaggcccagt aaacgtaatc
     6181 aatcccaaat ttctcaactg ctcgttgaac gcgttttttg gtgttatttg acactacgat
     6241 aatgccaata cccgcgtccc gaaggtcatg tagccattgc ttcatctctg gcgttccatc
     6301 agggttgttc caagcaatga gggtattatc caaatcgacc aaaacagcct tgattccctg
     6361 cgcctgcagg cttgggactg tcagatcata gactgcttcc acagcaaaat ctggtatata
     6421 attttcaatc gccattctgg ctccttttct taactttttt tcgcaatttt ccttagtaac
     6481 aaggataaaa caatccacaa acctgcacta gccaaactga tatagagcca agcatggggc
     6541 tcatctgtta aaggtaaggg aacattcatt ccgaaaaagc ctgtcacgac tgccaaaaca
     6601 gctagcaaga ctgaaatgat agtcaaggtt gtcaaattgt cattcagatt attgtttaga
     6661 atattgttgt aagaggctga aagctgctgt aaaatctgag agattaggtc tgtcatggat
     6721 accagctgat gagcctcaat catggcatca tcaaactgtt ctctctcaat ctcatcaaaa
     6781 ctacgataca aggcatgacc ttgaatatgc tctaacaaaa tccgattttg tttggcagct
     6841 gccgtcagat aaaccatacc agtctccaaa tcagacaggg caaagaagtt tttcttggta
     6901 gttcgctggc gcaagaggtc attgacctca tccctactct tgtccatctg ctcaatgaca
     6961 ggatagtagg cattgctgat gatttccaga ctggcaaaga gaaacttata aatcgaaagc
     7021 gtgtcatggt tctccagata acgagtcatc tgttcaatga cataggcgtt cttggtatta
     7081 ctaatggtaa tcaggcgacg atgctcgaca ataaaggtca tgggaaaagt ctcatagtag
     7141 gccttgtcct tttttacgtc taggacatta tagataaagg taaccgtccc actttcacgg
     7201 tggtagtcca tgtgggcgcg ctcgtttcta tccagtgcgt attcaatggt ttccttgtcc
     7261 aaaccgtaaa tttcagaaag gtcttctagt ttattcaact ttcctaggtc taggtctatc
     7321 caggtacaac cattgcccaa ctgcttttct aaaaccatct tttctcctta ttaaactccc
     7381 tctattgtac cacaaattac ttaaaataac aggtctagtc tgtgcgtgag aaattgctaa
     7441 caactgtgat atttcggtta gggacaaagt gaaggacttg ctcctcgcta cgaagctgtg
     7501 tcgtacgaat tcccacactg acaaccttac ccgacacagt aatcggtcca tttgtcagaa
     7561 cgacctcatc tcccacatcc agttgacgtt caaagaggat gaaaaagcca ttgatgacat
     7621 cagacagaaa gccttgggct cccataccaa tcgctacccc agcaatacca gctccagcca
     7681 gcaaactaga aactggcaaa cctaaaatcg acaaaatgca gtagagtaaa aagaaatata
     7741 gcgtataatt aaacacattt tctagtaaac gtgagatggt tttttggcgt ccgacatcat
     7801 gacgagacat ttttagagaa ggtttgacaa ttctctgcac catggtatga agcatttttt
     7861 tagcaatata aaatacaatc aaaagcagta aaagagaaat gaccttggtt agaatattct
     7921 cgataatggt tgtcacatct agcttttcaa tataagcctg aataaatttt tgcatataaa
     7981 actcctttat ttcattatac catattttca tcagtctcat tctccataaa tattcaaaaa
     8041 atagacagaa aattcttgat tttgtctatc atttatacta taatcataat cactacacaa
     8101 aaaggagatt attatgaaaa gaatcattca tgcttggaat aaggcaagcc ttgtcaagcg
     8161 tatcttgatt ggtatgcttt atggggaatc ctaggactga cccttcctaa tctctcaggg
     8221 attgggctac tcggggattt attcgttgga ggtctaaaag ctgttgctcc tatcctagtc
     8281 tttgccctcg ttgccaatgc cctttcccaa catcaaaagg gacaagatag caatatgaaa
     8341 actgttgttt tcttgtatat cctatgatag ggactttcgc cgctgctctt gtagctgtac
     8401 tagcaagttt catcgtccct attgaaatta ccctaaatag tgccaatact gaaattgcac
     8461 caccagatgg gattgggcag gtcctcagca acctcttgct caaactggtt gacagcccag
     8521 tcaacgccct gcttactgct aactatattg gaatcttatc ttgggcagtc atttttggaa
     8581 tcgctatgag agaagccagt aaaaatagta aagaattgct aaaaactatc gctgacgtga
     8641 cttctaaaat tgtcgaatgg atcatcaatc tggctccatt tggaatcctt ggtcttgttt
     8701 ttaaaaccat ttctgacaag ggagtcggaa gccttgccaa ctacggtatt ttattggttc
     8761 cattagtaac gactatgctt tttgttgccc ctgtggtcaa ccctttgatt gccttctttt
     8821 ttatgagacg caatccttac cctctagttt ggaactgcct ccgtgtcagc ggtgtgacag
     8881 cctttttcac tcgtagttct gcgactaaca ttcctgtcaa catgaaactc tgccatgacc
     8941 ttggactcaa cccagatacc tattctgttt ctatcccact cggttctact atcaatatgg
     9001 ctggagtagc gattaccatt aaccttttga cccttgctgc agttaacact cttggaattc
     9061 ctgttgactt tgccacagcc tttgtcctca gtgtggtagc agctatctca gcctgtggtg
     9121 cttcaggtat tgccggaggt tccctccttc ttatcccagt tgcttgtagc cttttcggta
     9181 tttctaacga tattgccata caagttgttg gggttggttt tgtgattggt gtcatctaag
     9241 actcatgtga aacagccctt aactcttcta cagatgtcct ctttaccgcc gttgccgaat
     9301 acgcagcaac ccgtaaaaaa taactcatca aggcaagcct gctcatgtct tgtcttttac
     9361 gcttttattc taacttatta ggaaattctt atgtctatta gccaacgtac gaccaagctc
     9421 atcttagcta cctgtcttgc ctgcctgctt gcttattttc tcaatctttc gtcagcagtt
     9481 tcggctggaa ttatcgctct cttgagccta tctgatacgc gtagaagtac tttaaaactg
     9541 gctcgcaatc gtcttttttc tatgcttcta gctctggcta tcggtgttct agcttttcac
     9601 ttgagcggat ttcatatctg gagtctcggc ctctatctgg ccttctacgt tcctttagcc
     9661 tacaagatgg gctgggaaat tggcatcaca ccaagcactg ttttggttag ccatctcttg
     9721 gttcaagagt caacctctcc agaccttcta gtcaatgaat tccttctctt tgctattggt
     9781 acaggatttg ccttgcttgt taatctctat atgccttcac gagaagagga aatccagcac
     9841 taccacacgc tggtggaaga aaagttaaaa gatatcctcc agcgcttcaa atactattta
     9901 tccagaggag acggacgcaa ccgagcacag ctggtagcag aattagacac gcttttgaaa
     9961 gaagccctca gactggtcta tttggatcac tctgaccacc tctttcacca gaccgactac
    10021 catatccact actttgagat gagacagcga caaagtcgta tcctgagaaa catggcccaa
    10081 cagattaaca cttgtcacct tgccgccagt gaaagcctga tcttagcgca actcttttca
    10141 aaaattgcag gtcaactgag ccagaccaat cctgcttctg atttgctaga tgaaattgaa
    10201 cgttatctgg aagtcttccg gaaccgcagt ctgcccaaaa caagagaaga gtttgaaacc
    10261 cgcgccaccc ttcttcaact cctacgtgaa gccaaaacct tcatccaagt aaaagttgat
    10321 ttttaccaaa aatatagaca gtaaaaaata aaaccactaa aaaacagagc ttgccagcat
    10381 tcttgaaaag tagtataatt attgcatgcg caatcatctt gtgacgcaga gactgcccgt
    10441 taatggactt tcttctatat tatgactcta aaaagaaagg agacactatg acctatttgg
    10501 aaaaatggtt tgacttcaat cggcgtcaga aagaaattga aagtctcttg gaagagacca
    10561 ttgcccaaca gagcgagcaa agtctgacct tgaaagagtt ctacctgctc tactatctgg
    10621 acttggctga agaaaaatct ctacgccaga ttgacctgcc agataaactt catctgagcc
    10681 cgagcgcagt ttctaggatg gtggctcgct tggaagctaa aaattgcggt ctactcagtc
    10741 gcatgtgttg ccatcaagat agacgctcta gttttatctg cctgacaaat gatgggcaaa
    10801 agacactggc ctcgctacaa aagactgtcg aagaaagctt ggaagcaggt ttggatttct
    10861 tgatttaaga tgattttaaa aaaagttgcg tgcgcaatca tttttcttga cattctcttt
    10921 tataaggagt aaaataaagt tagcattaaa caaaggagtt ttaaatatga ttgaaattac
    10981 ctatatagat gccagcaaga acgaaagaac tgtgactttc gagtcttatg aagactttga
    11041 acgttcacaa caagcttgcc ttatcggcgt cgcagactac taccctgtcc aaaaattaac
    11101 ttacaagggt cataatttgg actaccatgg gacttatgga gatatcttct tctatctcat
    11161 gaaacaagat ttaagccaat ataactaaaa aaaggagaaa tacaatggca aaagcaatta
    11221 cagatgcaac attcgaacaa gaaacaaaag acggtttggt cttagtagac ttctgggcaa
    11281 cttggtgtgg tccatgtcgt atgcaaggtc caatcttgga caaattgtct gaagaacttt
    11341 cagaagatgt cttgaaaatc gttaaaatgg acgttgatga aaatccaaac acagctcgtg
    11401 cttttggaat catgtctatt ccaactcttc tcttcaaaaa agacggccaa gttgtcaaac
    11461 aagttgcagg tgttcacaca gcagaacaaa tcaaggccat cattgctgaa ttgagctaat
    11521 caaacgagag accaagtact ttatttggtc tcttttttct tgccctttgc catttttcaa
    11581 aaaatatgct agactatagt agattgaaac tagaatagta cacctctact tctaaaacat
    11641 tgttaaaaat cgatttgact gtcctgatcg atttatcctg tttttatttc attttactat
    11701 ataagtagaa tattacgatg tttgggatat gccatcgcta aaaaaaactc gatttggtat
    11761 tttttagttc cctaatggga gctttttgcg tgctctgaac atttcccatt ttggaaggag
    11821 tactgtgaaa cgtcaatcag ccttggtcgt ctttagtggt ggtcaagatt caacaacctg
    11881 ccttttctgg gccatgcaac actatgaaac agtcgaagct gtcacctttg cctacggcca
    11941 acatcatcac ctcgaaattc aaattgctag agaaatcgcc aaggaacagg gcattcgtca
    12001 ccatatcctc gatatgtctc tgctgggaca aatcactgct caaccagact ttgcgacgat
    12061 tcatatttcc tacattcctg acaagctctg tgtcgagtca aaatccctca aactatatct
    12121 atttagctac cgaaatcacg gagatttcca cgaaaactgt atcaacacca tcgggaaaga
    12181 cttggtcaac ttgctagacc ctcgctattt agaagtctgg ggaaaattca ctccgcgcgg
    12241 tggcatttca atcgacccct actacaacta cggtaagcaa ggaactaagt atgagggctt
    12301 ggcagaacaa cgcctcttcc aacacgacct ttatccagag aaaattgaca accgctaaag
    12361 tcatactcaa tgaaaatcaa agagcaaact aggaagttag ccgcaggttg ctcaaagcag
    12421 tgtttgaggt tgtcgataaa actgacgaag tcagcttaaa acactgtttt gaggttgcag
    12481 atagaactga cgaagtcagt aaccatacct acgacaaggt gaagctgacg tggtttgaag
    12541 agattttcga agagtatcat acgaaaaagc cctgttcctc aagatgagga gcaaggcttt
    12601 ttgagtttca attattcttc tgttccaagg aaattttttg caacaagggc tgcaagaact
    12661 ccaccagcga ttggtgcaag gatgaaaatc caaacttgtt gaagggctgc gccgcctacc
    12721 aagacagctg gtgccaagct acgagctggg tttactgaaa gtccagtaat cttcaatccg
    12781 acaagaatca tcgccatcaa tgacaaaccg attaccaaac cagcaatcgc gccattgccc
    12841 ttgctttctg aagtcacagt catgataacc aatacaaaca agaaagttgc gatgacttca
    12901 aacaagaaac caccaaagac agtgacaccg tttgccaagg cattttcacc aagactagca
    12961 gttgacatac ctgagttagc caagaggaag aagacagcgc cagaagcgat gaaagctcca
    13021 acaacctgac caaggatgta gtttacaagt tctgaagatg acaaacgttt gtttacaaac
    13081 atagcaatcg aaacagccgg gttcaagtga gcacctgaaa cagttccgat tgagtaggct
    13141 gccaccacga ttgccaaacc aaaggcaaag gcgattccaa ggtgaccaag gccatcaaga
    13201 ccatttccaa aaacaacagc tcctgtcccg acgaatacaa gcatgaacgt accgattaac
    13261 tcagcaacaa attttttcat tttctttctc cttttttcaa aaactagata ctagtctatc
    13321 aaaagtagga aagggtttca agaaaattga ttggaaattt tttgaaaatc atagaactat
    13381 tagctaatct ctagtattga aaagactgga tagcttcttt caactcatct tgtaaactat
    13441 ttctctggtc aagttggaca tagacttcca ccagacagga tctaaagttg gaaaatttgg
    13501 aaaaatcctc cctttcttct atcggaaaat caacagtttt tatccaagaa gctacttgtt
    13561 cttgctccaa cttcccttgt aaaataggtt catagatcac tcttgctaaa cgccaatcct
    13621 catcatctgt aaagcgaatc gacattcttt taaatagttg gccaagtata tcaaatactt
    13681 catgaactct gtttttagga aagtctggat gacaaaccac ctctgtcagt aaatcggctc
    13741 catgtgcaaa agaatgaacc caaccatact gacttgagaa acctgttgta tccttttctt
    13801 ttgaaagata gtgcaagcct tgatttgaaa gatcatcacg aatttctgat tgtaatccct
    13861 gataaaaaac cgattgctgg ttagcatctg cagacaagag atttgcataa acaagtgccc
    13921 taaaagaacg ttccagtgtt ggcaggccta ccttatcaat ctctttatct agtcctacat
    13981 cagatgaaac cccttcagca atgaaatgaa attgctcctg tataaatagc tcttcctgaa
    14041 tccccttagc aaagcttgta aaaataaggt catcacgaat ttctggagaa ggatttccca
    14101 aatgatcaaa caaccactgg atttcttcct ggttataatt tggtttttct tctgctattt
    14161 ttcttagtaa atcttgatac atggtcaata cctctacatt tctagcaact gttcaaaaag
    14221 gcagtcttaa atgaccttac caatttgtaa aattaagtta aaaagaaaaa gacatttata
    14281 ttcagagaaa cagcatattt ctgaaaagat atataaatga tttattccat attacaacaa
    14341 ataaacttgt aatgatagag ccttatcaca aaaatcacat tcctgtctca aaaattgcga
    14401 aaaactagtt ataataaagt gaaataaaaa ctatacaaat tgattaggga atttaaaaca
    14461 atttctaaca atattttaaa aactgaaccg tactatttca acttccataa attacaatat
    14521 tgataggcac agttcccata cctgtccaaa ttcgaataac gtttagtata aattagaata
    14581 tgactacaac atcacaaata attagactat ctataatatc tacgatgtaa catatacata
    14641 ggaagcaccg ttatcaagag cgccaaggct atcaaccaga taagatgaag atacaaacct
    14701 gtcacctcac ctccccatat aatacgaatc atgcgagtag catgatacaa gggagaaaac
    14761 caagtcaaat caccaagtat tgggggcaag gaagtaatgg gaaagaaggt atctgaaaac
    14821 atataaagag gacggattac caaaacattg tagtaattca gaaattccct agacggcgcc
    14881 aagtaggtaa agattagtcc caaaacacca aacaaataac ccactataaa taaaatcaga
    14941 ggaatcaata acatcaagac atgaaaatgc gctgtgataa gcatggaaat cagccaaaaa
    15001 atcccaccga aaatcactgc acgaatacct gcccagatag cctgacccac cacaatatca
    15061 ctcgtattga ttggcgtcat caacatagca tcataagtct tttcaatctt atactggata
    15121 aaggcattga ccgttgtttc tgcggtggcc gcagacatgg cagtcgcagc aattaaacct
    15181 gtaatgacaa aatcacggta gagcataccg ttaacatgcg tcaaataggc accaactcca
    15241 aatcccattg ctaaaagata aaagaggggg tcgataaggt tggggacaat tgaaatttta
    15301 aataaatttc taaaactcat gtagttgcgt accacaacgt gtccgatgga ctgaaatgat
    15361 aacttaaaca tgcaagtcct ccttctctgt cccagtcaac cccaaaaaaa gcgtctcaag
    15421 gttgtcagca tcatacttga tgagcaagtc ttctacagtt ccttcttctt tgatagtccc
    15481 ttggtggagc atcagcaccc tatctgtcaa atattcaatc tcattcatat agtgggaagt
    15541 aataatgatg gaaacaccta attccttcaa ctccaaaagt ttatcccaaa taatattgcg
    15601 ggattgaatg tctaaaccaa ctgtcggttc atctaaaatg ataatatcag gtcgattgat
    15661 gagagctctt gccaagacaa gacgtcgtcg catcccactc gacagctgat tcaccatctt
    15721 ttgcgcatgt ttgctcagtt gaacaaaatc caagagagaa tcgattctct tcctaagttc
    15781 gacagatgag ataccataac atagaccgtg agcaaaaaga ttatcataaa cattcaaggt
    15841 catgtccagc atatcctcct gccctacaat acccagacaa gatttactct tacgacgatt
    15901 ggtttcaata ttttgcccca agatatcaat ctctcctgag gaaattgagg tcagtgagta
    15961 aatcatcttt aaagtggatg ttttgccagc accgttgatt cccaagatac ccaaacactc
    16021 tccttatccc aattcaaagc taattccctt gacagcttca taagaaccat attgcttttt
    16081 tagattttta acacttaact tcttcactct ttctttcccc cacaaataga gcatgttgga
    16141 tactttgtta attcatctca cttttgacaa aatgttgaga atgtaatctt aagattaacg
    16201 tccttcaact gtggatactg ctgcaattac ttttgtaatt ttacctccat ttaaactcag
    16261 acaataaaat ttaaaatatt ctctagtaaa acatttttaa aatctatttt tcttgtgctt
    16321 taattatagt ataataaaag atagaaaatc atcgatatat gaaatttgga gaaaattttt
    16381 atggaaccag atattttcat catcacaaaa ctcttatcag acccttctcg gatgcacatt
    16441 ttagatattc taatggatgg aaaagctcac acggttaacg aaattgccag ctttaccaaa
    16501 atcaagcaac atactgtcag ctatcacctc aaattactta ccgaagcgca ggtaaccact
    16561 ctacaaacct atggacgttt tcattattat tctttaaaaa gtgctgccat tgcagaaatg
    16621 ctggaatttc tcagcttcta ctctcctcag cgtgatgtca aaagttataa acaacacatt
    16681 cacaaaaagg aattaaaggt cgctcgcacc tgctatgacc atattgctgg tgagcttggc
    16741 atttccatta ccaattatct cttgcaagaa aatctcctca gcgaatcaga aaaagacttc
    16801 caactcactg aagctgggaa gtcttatttc caaagaaaat tacacattga tacggatgaa
    16861 ttgaaaaaga aaaaacggaa attttgccct aaatgtttgg attggagcga acgtaaaaat
    16921 catgtcggcg gagctctcgg caatgctctt ttagaatttt tcagtgaaaa acaattggtc
    16981 atccctgcac aaacgccacg ttcacttacc attacagaga agggcaaaga attcctcgaa
    17041 aaggaatggg ggatttaaac atggactttt aagcaaataa ctgtccatac ccattctata
    17101 acaacctctc tatcccctta ctcccccaac tcagcactgt aggcgataat ctggtcaact
    17161 gtgtcagaca agaattggat ggtatcacgg agtggtttgt ctgttgaaat atcagcaccg
    17221 ataatcatgg ctgactcaag tggtgtcttg ctaccacctg atttgaggag attgagccag
    17281 tcttcagctc cagtttctga gtttttaaga tgaaggtaac cagctgtcga gatgacaaga
    17341 ccagcagagt aagtgtaact atacaagccc atatagtagt gagcttggcg catccaagtc
    17401 aaagctgcat cgtcgtcgat ttcaatggca tcgccccaaa aatctgtcaa aacttccttc
    17461 ataatgctgt tgagtttgct tgctccgaag gtttctcctt cttcaatcaa tgtatacacc
    17521 ttacgctgga aggcggcttc caagaggtgg gtgataaagt tatggaagta ggtgtctgtc
    17581 aagcgatgag ccagagcgaa gcgtttttga cgtgggtcat tagattggtt ctctaagtaa
    17641 tcactgagta gcaattcatt gaaggtcgac ggtgcttcaa cataataggt cgacatgtgg
    17701 gcgttgaaat agctttggtg attgtctgaa aagatgaatt gaccagaatg cccgatttca
    17761 tgaatcaagg tatagacatc gctcaaacgg cctgtccagc tcatgagtac ataagggtgt
    17821 acgcgatatg ggtccgccgc ataaccaccg gaatccttgc cactgttagc agcaaagtcc
    17881 acccagcgct cttcttgata acgagcaact tcctgacaat attcttgccc caaaggttct
    17941 accgacttca tgaccaaatc ataggcatcg tcaatagtca cttcaggatt gagggcgctg
    18001 tccaagtcca atttccagtc tgcaaaggtc atcttttcaa gaccatttac cttggcaaca
    18061 tgcttgaggt atctctgagc gactggtgca aagtccttca tgatgaggtc aatctggcgg
    18121 tcaaacatga cacggtccac ttcttgttca gctagaagat agtcaaagac agagtcgtat
    18181 cccttcatat cagccaagag tttttcagac ttgacctgag ccagataggc tgctgcagcc
    18241 gtattttggt gcttacgaag tccctctgag aaggaacgga aggatttctc acgaacctca
    18301 gcatcctcgt gattttggta gaaattctca taggtgacaa agctgttttt ataggtcttg
    18361 ccatgggctt caaagtcagc catttcaaaa tccccagctc gcatcttagt ataaatgtcc
    18421 tgcggactat agaaaacttc accgagattg gtcaaggcct tctccacatc agcccctaga
    18481 tagtgggctt ttttgatttt ggcctgacga atagctgccg tcaagtgagg caattcaccc
    18541 aaacggtcca agacttcctc gtctgctacc accaaggcat cgtcaaagaa ggtcaaggct
    18601 acgctggcat ctgtttcaaa ttccatccca gcttgggcaa tattggcaaa ttcgtcattg
    18661 ctatagtccg tcgtctgagg cataaaagca tagttgccaa tatggctcat ctgaatgtag
    18721 atctgttcca attccgcaaa ggccttctcg aaatcctcaa aagtgtgaag attgcccttg
    18781 taatcacggc taaactggtt gatgtcttca cgagctttct cgattgcacg caagaaatcc
    18841 tcacggtctt ggtatagggc tgttaaatcc cagagttcct tctctggaaa ttctgaacgg
    18901 tgtttttgtt ccattttctt cctcttattt ctctaattct actaaaacac taagggctga
    18961 taaggcgtaa agcggtgctg tttctgctcg caaaatacga ggacctaggc ctgccaaaac
    19021 tgctccttta gcttcaaaac tttcgatttc tgcaggtgac agaccacctt ctggaccaaa
    19081 gataaagagc agtttggctc ctgtttcaag accagtgact gcttgcagaa gcgcagcggc
    19141 ttctccttct ttagctgatt cttcataggc tactatgata gagtcaaact ggtccagctg
    19201 agctagaaaa tctgcttttt tctcgaaaag tttaatactt ggtacaatat tacgcttgct
    19261 ttgctcggct gctccaaggg caattttttc tagtttttca acttttttac ccaatttctt
    19321 gccatcccac ttggcaactg accagtctgc aggaaaggcc cagatttggc tagcacccag
    19381 ttcggttact ttttgagcga tgaactccag cttgtctccc ttgggaaatc cagatgcgat
    19441 ggtcacttgg actggtagtt ccacattgtc atttaattct tggaccaact caaactgacg
    19501 attttccata tccagcacgc gcgccaagcg cttgatgcca tcatcaaaga ctaaggtaac
    19561 ctcatcctct tctttcaagc gcataacctg aaacatatgc ttactggttt ccttgtcctc
    19621 gatagtgaca ggagagatag cactgccttt tacaaaatac tgctgcatgc tagcctccaa
    19681 tcacaccaga gatatccttg gttttcttaa agacacaggt attccattcc ccttgaacca
    19741 tgtgagtttc gaggaaaaat ccagctgact cagccgactg gcgcaccatg tcccacttgt
    19801 ccttgataat gccactcatg atcaggtagc cttcatcctt taccaagcga taagcatcct
    19861 ccgtcagatg aatgagaata tccgccaaga tattagccac gatgacatct gcctcaattt
    19921 ccacaccctt aagcaaatct ccagccgcta catggatatt ttccatgcca gggttgagct
    19981 caatattttc ctgagccaca cgaaccgcca catcatccag gtcataggcg aaaatttctt
    20041 tagcccccag aagcgagctg gcaatagaga gaacccctga accagtcccc acatctagca
    20101 ccgtttcgcc accacgaaga acctgttcca aggcaaaaag gctcatcttg gtagttgggt
    20161 gggttccagt accaaaagcc atgccaggat ccagcttgat aattttttct cccgcagtcg
    20221 cctcatagtc tgtccaagag ggaacgatgg tcaaatcatg agtgatacga gctggctcat
    20281 agtatttctt ccagttatct gcccagtctt cctcagccaa ggcagtcgta cctattttta
    20341 actctcccaa atccataaaa tccgtcaatt ctgatatgcg agcctgcaag tccgcctcaa
    20401 ccactgtcac atccaccgtg tcagggtagt aggctgtcac tacgatttct tcttgctgct
    20461 cgacctctgg gaaaatctcg ccgaagcggt caacatttcc cacatagtcc agactgtctt
    20521 caatcgcaac accttgcgct cccagctcaa tcaagagatt ggaaaccaac tcctctccct
    20581 cacgcttcac tgtaactttt aactcttgcc atgtttccat tatgtatttt gcttaccttt
    20641 ccatcagatt aaaaatagtc tttccaataa caacaataag gttatctctt aatttcttct
    20701 ctaactctaa atcaattcca ctattttgta tgaatttgtc ttctacattt ctatataagc
    20761 gttttactct agtggggttt cctgcatcaa aatgaggtac ataatggtaa attatgacag
    20821 gaacagaact tctgattgat tgttcagcaa tctgattcca gatataccca tcagtctctc
    20881 ccaaagaaac cccataaaga attatgatgt cagaattttt tataatatcg ctatttttaa
    20941 catccatatt ttctctatag ttcttcaaaa ctaaattttt tattaaggat tctttttgtt
    21001 cttcatcaaa actatttgaa atctgtgtct cgtcactaac tcctaaaact gtgcaaatat
    21061 ctaccgttcc atgtgcatga attggaggcg caatgtgaaa tttataatta ttagttcgta
    21121 attgattgct aaatgatttt gctgactcat tatataattt atcgattaca tttgtgtaat
    21181 taagagttaa tatattcacg atatcgtgtt gatatagatt ttcattatat tttttatcga
    21241 tagcaggttg attaattaca gggagagagg tcctcatatt atctagagtg cttataaagt
    21301 caattgcatt acctttctca agattttttt cttgttgtat gcgtagatat tctcttaaat
    21361 catcaactac ttcactaaaa tcatctataa atttctcctt tatttctata cttgaggaga
    21421 tgaggtcgtt atcttttgtt aatttaccaa ttgacaattc aaaatctgac caattttcat
    21481 aatcatttac tttatcagaa aatagagact cataaatgaa atttgaatat ttttcctcgt
    21541 tctctgtcct acttatataa accttatttt ggaattcgta gaaatcccta tatcttgttt
    21601 tcaaaccata ttgcaaatcc aaaccatttc caactatata agtaatattc atatctttgc
    21661 cctcttgtgt tcctaagatc taaaataagg ataaaatatc cactattcaa attcaatttc
    21721 ttcatttaaa ctattaaaga ggtctacttg agcttctact tgcaatctat taactagcca
    21781 accgcgtaat tcagcttgct gaataaaatc ttcaatacga ttaaccccat ttaattcttt
    21841 taatgtaact actacaccaa aacgtactcc ttgtccatca ccgcttttca aacgttcgat
    21901 tgttttaata ctcatccccc actgaggatt agatggattt aaaattgctt tagctctctt
    21961 tcgagaagta aacgactctc caatatgctt gacattatcc catttcctaa atatatttct
    22021 agcagcattt tctctcacat atcctgggga atcttcggca tgctggttgt ctttatttat
    22081 cgatttgata ccgtctgact ttaacctacc aaaagtaagc tgcatctcag tatttgtata
    22141 atcaacccct tgttttcttg agcagttagg gaaataacac attgttgctt tagctacata
    22201 tggataactc tcactagaaa taggtactgg aaaatcataa ttataggtat cataagccct
    22261 agagatatct gacacaataa atttaatttc atcatcaggt gtagataaaa tatcatccat
    22321 ttttattgga acaataccat ttcctatcaa agataaatca gtgaatgttt tcttatcatt
    22381 ccagggtatt gctgcatcaa ttagcaaagc cttcgcttct tctcggctaa gtcccataat
    22441 atgaatgaga taggccattt tccttgcaat aaaaggtgcc gcaaaacttg ttccagctac
    22501 acgacctaat cctagaggtt cacaaacatt tataaagtca ccatttcctc ctccataata
    22561 tgacacatct ggtttaacaa agaatgataa aacaataccc tctcgtgaat atgacactga
    22621 ttgattatta aaatcaacag aatttactat tatagaatta agtgaatcag caggagcacc
    22681 tattcttttg cgtttcccat ttattactga agcatttgtc ccagctatga taaaaattac
    22741 atcattctca aattgaattt cgtctaataa tgctccctct gcagagataa aattttctct
    22801 tatttcatca ttggacccta aagaaagatt ccaaacctta atatcagcat tctgagaaac
    22861 aatctctttt atctgtttta tgattgtaaa tgaattaaat ccactttgta gtgacacacc
    22921 aaaatgcctc actctaaaat ttccacaacc atcatccaga ttagggttca aattggctcc
    22981 atcaacgatt aaagaagtca cagctgtccc atgcttgtaa tcttggctat ctttgctaat
    23041 atcaggtgag acaaaatcat gatattctac ccactcatta aagtaaactc ttttgtcaaa
    23101 taaggtatca ataacgccaa caactggttc gttcattgga gatggaagat ttatttttaa
    23161 atcattatta tctaaagaaa aatcatctac agataactta gaaaaatctt ccacaatcat
    23221 ggagacaaga tagggcgctt ttgatagtag taattcaata tttttttcat caagcaagac
    23281 cgtggtctga ttcatgatat tagcttctga aatatcaata tttaatttat tcagtaatct
    23341 aaaaatgtct gtatggacat cataaaatgt cacgatagaa ttttgaatat cagaaacagt
    23401 agtgtgctca actccaaaat tctcaataaa gcaagaatct ctcaaatact gttgaaattt
    23461 gctttttgaa ataccatact ccgaaaaatt tatagaagca aacgttgatg aatcagaaaa
    23521 catctcacat gttatcgctc tatcaaaatg ttcctcaaaa acttcaatta tcttacttaa
    23581 aacggttatt gttttattaa gagcatctct agaaatataa tgagtaacaa tatgttttgt
    23641 cttctcatca ttgaattttg ctcccacaat agtatcatta gggaatggat tccctcctcc
    23701 tacattgaaa tagccattaa tacggttact tttggcaaca attcgattat agtaaatact
    23761 gatcaaaata ccatcgataa tgttattttt ctcccaatat gttttcgtct cttctaatga
    23821 aaaatgaaga tacttcaaat gttccaatgt aattattgtt tttttgggta tagttattgg
    23881 tcccatacca ttatttcttg atttttgtgt aaagctttta cctcgtaatg tcaataatgt
    23941 attcatttta atcctcgctt aactctcgtg atacactact cttagaaaca cctgtcaaaa
    24001 tctcaatttc tctaacagta aaacctagct tcgataattt agaaatagat aaatttctac
    24061 cattatgcaa acttcttagc aggcgttttt ggtaatcatg cggatctgat ggatcactaa
    24121 atgccaatga cgttcttatt gagtttctca aatcaccagg attcggtatt acattggcac
    24181 tattgataat ttttttaaat aattttaaat ctctagctac attcttaaat tgctttaata
    24241 actcatttaa aataatagta gctacttcta ctttatcttc atcagtataa cggtcaaagt
    24301 caattatggc atcgaatctt ctcgtaactg ctttatcaag attttcaaaa agatttgttg
    24361 ttgcaattaa tacaatttct ggtgacagcc tatccaactc ctttaaaaag gcagaagtca
    24421 ctcgtcccat ttctcttaaa tcattctgat taaccctatc caacactatg gaatcaattt
    24481 catcaaatag gatgatataa ttttgcttga aaggaagatt attgatttca ttaaaaagag
    24541 ttgctaagtt tttgactgtt tgccctagct tactatctac taagtgactg aaatctacta
    24601 caagtaattc cttgccaata agtctagcca cctgctttac actttcagtt tttccagtac
    24661 ctggagatcc cacaaataaa aatttattta ttccaatatg atgattgaca gcgtttatta
    24721 ttccttttaa atcattcata attgaaagag gcaatgggag aggaccaata tctagtttag
    24781 caggagtcaa atactcacta ggattttcta tttgtggcat gaatctatca ctttgagaca
    24841 ttaaccccat aatatattgt gctatttgtg tatcaccatg tttattgaag ttccgagcaa
    24901 ttgctatgga ttgatttcta aattctgtct ctctgccctc ataatgatac tttattaaat
    24961 caagaacatc tgattttttc atgattcatt cctccttata caaataatac tatattttcg
    25021 ggacaaagtc aattattttg ggacaaaatt aaaaaagaat aaccttgaaa ggatattctt
    25081 ttaatgcaaa actatatcag attttccctg acactctttc ccccacctgg cagttcccac
    25141 atattggccc agggaatgct tgccttatca tcgcgtaaga tagtcaaaag cttatcccca
    25201 caaaacaaag caatcttaca gcctgggaaa tcagaaattt ctagttccat cttcagttcc
    25261 ttctaacatt tccttttcca gctctgctaa caagttttca taatagcgtt tctcgtccct
    25321 caacattcga ctactatcca ttttctgtct agcaatcttc atagccttgt gagtttgaac
    25381 cacatctttc cttaccttaa attgatacca ggcttgtatc acttgaagat tggacagttt
    25441 gagagacaga aacgatttga cctgtcgaat actagcatat tgctccgctt gctcaaaatc
    25501 tccttccaac aaggcgatat gaagcaggga tagttgggca actgtctgca tcatcggagt
    25561 agttgtcctc tcaagtaatg cttgaaactg ctgtttagct acttcttcct tcccttccaa
    25621 aatggaaact tcaccttgca tacctaatac accatccgca aaactccctc gtgcatcctc
    25681 aggaactgct tgaacaaagt ctttcaaatc atattcttga ggagccagca aagtttgagc
    25741 agaatgtctc aataccaggt aggcgtattt ggtattttca gggtgttgta gtaattccca
    25801 aatttttgct ccatcggtga tgtcgactgg caaaatgtta tttaggaaga aagataaatt
    25861 aagaaaaatc caagtccctg caaaatacca gcttcttgtc aaaaatccaa acactatcgc
    25921 caataatatc aagccgagat gaaccatcaa gcctcctgaa agcatcagga tgattctttg
    25981 atcgctttca tcctctttta aaccaatgta ttgagcacca acatttttca gaatggctgt
    26041 tctactaaga tgaaacctgc ctgacttttt ggtcaaaata aaatgtccta atccaaaagc
    26101 caccagccga tagcctgtca agtagccaca aaaagcatga cccagctcat gaagaataaa
    26161 gattaaatac atgcttagaa gagcgaaggc ataaccaaaa gtaaaggcta aaactgcgga
    26221 ataccccaac tctgcaaatg cgattgttcc acaagcaaaa gctagcataa taaagacaac
    26281 agctaacaca taaaccaaat aagtcccaat tttcttcata acacctccaa ccaactccta
    26341 gtatcttgga taaggataaa attctccctc ttccaagcca acttttcctt cttcaaagac
    26401 ttcttgattc cattccataa caaattcctc tgcttctgga tcttccaaaa agtccatgag
    26461 ggtatctagt ccaacctcag cagtatcttt aaggaaaagg gcaaaataag ctaaaaattc
    26521 acgggaaaat ccttttttag gcaggtaagg aataacagtc aaatagtctt cctcattgac
    26581 tgttgacttg gcaggattgt agaaaaggac cgcttcctca aaaagaatgt catctgataa
    26641 aacctctccg tcttcatcca ccatctccac acctgcagca ttttgcgctt ccaatagaaa
    26701 actcacttct accgcgtggt tacgcttgtc ccaactaatc tcaaagtcaa agggaaagtt
    26761 cttgtccaac tcttcctcta aaatatctaa aaatccgtat gttgccattt tgtcctcttt
    26821 ctatgcgact ctttaatcgc cccgattgct cggaaatatg ctaaaataga tactaccatc
    26881 ttaccacaaa attattttat gtcctaatta taccatatta cctcatttaa acccttggta
    26941 tcaatgattt tcttaaaagt ctgatttctt catttctcat aaaaatcaat ataaaaagcc
    27001 ctcgaaaggg ctaataaatc tataaaatca ataggcgagt aactagcaca agtggacgtg
    27061 cttttttatt gactattacc acgataccac gcttaatctt aggcttgaac tttcttatct
    27121 gcaatagcgt ctgtcaaagt ctgagaaaag ttaagtccca tttctcgtcc caacttatct
    27181 gcccattttg gtatggtcaa agtcttttta atgggttcct gacttcctag gtattctgat
    27241 acatcaacag ataccataga aataaaagat ttatcaaggt cataggttga cacgaaatct
    27301 tcatcatctt taaaaggatc attatcaatt aaagacaagc tattgatatc tgatggctga
    27361 ggtaactctc catcactctc tatcaaatct gcaacagtta tccctagcca ctccgacccc
    27421 atagccaaag cctcagaaat cccctctcct tgtgtagctg agtattcaaa atctgggaaa
    27481 tggacaaaat aagtcgcttc tgttccgtct gtgtcgtcat aataaaataa agctggatac
    27541 gtaactaaca tttcactacc tccatatcaa aaagcaggga ctgaatttta caacccagct
    27601 tgctttccta tccctctttc agtgtactta ttcagctcac catgaaggat tgtgataggt
    27661 ctttcccctt gcttttccat tttaatatgg gagcctttac cgcctctagt ctttatccaa
    27721 ccatgggccg taaggagttt aaccatctct ttttgtgtca taggtatagc gcttttacct
    27781 cctgacaaca ccattacaac acgtgttaca cgtattgtaa aggagtgata cttattattc
    27841 tattatacat aaaagcccct agatgtggtt ctaagggaaa ccaatttatt cagacctatt
    27901 tttctaatga gtagtaaaaa ctgcttcttt atcgagcaat tcatcatctg tatagtcaat
    27961 tgtaaaagta tctcgatcta agacagattg aggcggagtt gaatgaatca taggaccact
    28021 gcgtactcta tattttttat ctccaatttt tacaaactga tactcttcga aaatcaaatt
    28081 caaaccacgt caacgtcgcc ttaccgtact caagtacagc ctgcggctag tttcctagtt
    28141 tgctctttga ttttcattga gtatgattaa ctctcaagtc ttcgaaatca ggattttcaa
    28201 cagttattac aaggaggcga tttactactt caaaaacatc aattattcta tttttcatat
    28261 tttttcaacc cattattaga atgaacttct tggtaagcaa aatcaagttt agatttaatg
    28321 ttttcgtaca aatctaaaat ctcttttgga gtatcttccc ggaagaaaag ttttcttttc
    28381 cctgaaataa cttgatcact aagaatccaa tgacgaattt gttttgtaaa aatcaaaatt
    28441 tcctgacttg gtccatcatt tccattgctt atcacctctc ttttcattat agttcataca
    28501 atgacattca gcaatattat ttctcaagtc agcacttcca cttctttagg ctcaactatc
    28561 ctattttgag ctttaaggaa aatcaaatct ctcatgctga tacctctcct cattaaatta
    28621 aatagtaaaa aagattctat ctcactccct gattattaca aaaccattga aatatcacaa
    28681 ctaataggct agaatggaca tagtaagata tagtagatga gtcattctac tcaaatccac
    28741 gttagaaagg actgctatgc cagacaatct cgcgcttcgc atgcgcccta aaaccatcga
    28801 ccaggtcatc ggtcaggagc atctggtcgg acctggaaaa atcatccgcc gcatggtgga
    28861 agccaaccgc ctgtcctcca tgattctata tggccctccg ggaatcggca aaaccagtat
    28921 tgcctctgcc atcgctggaa cgaccaagta tgcctttcga actttcaatg cgacagttga
    28981 tagtaaaaag cgactgcaag aaatctcgga agaagctaaa ttttctggtg gtctcgtcct
    29041 attgctagac gaaattcatc gactagataa gaccaagcaa gacttcctct tgcctctctt
    29101 ggaaagtgga ctggtcatca tgattggagc aacgactgaa aatcctttct tctctgtcac
    29161 tcctgccatt cgtagccgtg ttcaaatttt cgagttggaa cctctgtcta accaagacgt
    29221 caaagaggcc ctgcagatag ctctaagtaa ccctgaacgt ggttttgatt ttccaataga
    29281 actagatgag gatgcgctgg atttcatcgc aacctctaca aacggagacc ttcgctctgc
    29341 ctttaactca ctggacttgg ctgttctctc tacccctgag aatgacgagg gcattcgcca
    29401 catcacctta gacatcatgg aaaatagtct tcagagaagc tacatcacta tggacaagga
    29461 tggagacggt cactatgatg ttctatctgc cctgcaaaag tctatccgtg gctcagatgt
    29521 ggatgccagt ctccactatg ctgcccgctt gattgaggct ggggatctgc ctagtctcgc
    29581 tcgtcgcttg actgttatcg cctatgaaga tatcggctta gccaatcctg aggcccagat
    29641 tcataccgtg actgctctgg atgctgccca gaagattggg ttcccagaag cccgcattct
    29701 cattgccaat gtcgtgattg atttggccct ttctccaaaa tccaactcag cctatgtagc
    29761 tatggataag gcacttgctg acctcaaaac atcagggcac ttgcctattc cgcgacacct
    29821 acgtgatggg cactacagtg gaagcaagga actggggaat gcccaagact atctctatcc
    29881 acacaactat cctggaaatt gggtaaagca agactatctg ccagaaaaaa ttcgtaatca
    29941 tcactatttc caagcagaag atactggtaa atatgaacgg gctttggctc aaagaaagga
    30001 agctatcgac catttgcgaa aaatctgaaa tccttttcaa aaaattgcac tttcctcttg
    30061 atttttttta aaaaagtggt atcatataaa tatagaaacg ctgtggtgta cgacttcaca
    30121 cttaagtgtt gaccgactat tttttgtatt attagggaaa caaaagtctt ctaacagcat
    30181 gtaggccgtc tcacacggaa acagcttcag ttagagcgag ttgcccacct gcttaattgc
    30241 gcgggttcaa tacaaaccgt gaagtttcgg caccaataca gcttttttct ttgcctcctt
    30301 agctcagctg gcagagcagc ggactcttaa tccgtgggtc acaggttcga tccctgtagg
    30361 gggcatataa atacaacagg aaaagccttg gaaccaaggt ttttttgctt aaataaaatt
    30421 tttttcaaat tctttagaaa actagcttaa atcataatcc aacaccaatt ttacaaatac
    30481 cataaactaa gcttatatac ccaaaacaca aaaagtcctc tttccactat tttagaaaga
    30541 gaactttttc tttaggagaa ataacttaat ttttaatcaa ttcgtgatag ctcagctggc
    30601 accgttaagt aataagttgc agtcaagctt gcttcacctt gattgacaaa aatctcgatg
    30661 gaatttttat ctagaacaac ttccaattct ttagcttcaa tatctacata ccgtcgacta
    30721 gtgtcctgtt cttcttcacc tagaattttt tgaataagat ggctacgatc aatgtaaact
    30781 tgctgcgcat tactgtcata accaaattca agataatctg tatcatttcc taagtggtaa
    30841 tgacaatctt tatctatttg gatttgatat tggccttttt taacagggaa ttgtcttagt
    30901 ttgccatctt ccaatcttag aattctaggt aaagtcatgg cacatgccca tttgtgttct
    30961 tggtcatggg ttggaagggt acgcccccat gtctgcatcc aagcaatcag gatacgacga
    31021 ttttgatcgt ccaacaatgt ttgaggcgca tagaagtctt ggccatgatc aatttcttga
    31081 actgattctg ggataaaacg tttttctctc caatctacct tacccgtgaa caaaagcgat
    31141 gagttgatgt tatgatatga gtctccctca cgctgataac gcatgggtga cataataagg
    31201 caatctttcc catctaactc gaagtaatct gggcattccc acataaagcc ttggtgttct
    31261 ccccctttta aaaagatgga ttcgaactgc cattctacta ggttatcgga ccctagtaga
    31321 acgatacagc ccacattatc catgtgtttg gcagctacta cggagtaata gcgtccatct
    31381 ttttcaaaga gttttggatc acggaaatca gcagcaatca actcatctgg caagtctgtt
    31441 ccagttacaa ctggattttg ggaaatcttt tcaaagtgaa tcccgtcatc tgaaaatgcc
    31501 atattttgca cttggcggac accggttttt tcttcgatat gcccagtgta catgagccag
    31561 aggcgatcat ccttgacaat ggcagagcct gagaaacaac catttcggtc ataatcttgg
    31621 tcaggagcaa gtgccactgg caagtgctcc caagtcacca agtccttact tttagcatgt
    31681 ccccagtgca taggtcccca aacactatca tatggataga attgataaaa gagatggtat
    31741 tctccacgaa aataaacaaa tccatttgga tcattgatcc aaccaatctc agctgaaaaa
    31801 tgttcttcag gcttatattg agtattaacg agatgtttat tttctgctat aaaacgattg
    31861 gctttttcta ctgtgtattt cttatctccc ataatcaacc tctagttttt gtttgcttgg
    31921 tattggtcgt agtatttttg tttaatagcg aggtaatcag aaagtccgta tttttcaagt
    31981 tctttcttgt aatcatccca ctcagtatca atattgccat ttacaatcca ttcagcacgt
    32041 ttacggtaga tatagtcatt catatctgcc tcgatatggg caatcttgtc caaatcttcc
    32101 tgtgtcataa agactcttgg atagttattg tcattgctca tgtaaggaac ataatattct
    32161 ttgataagat ccaaacgcca tttggcatca tctggcatgg ttgtcacttt accatagtat
    32221 gaatctagaa tagctagtgg tcctcctact tcagtctttt gacgaagttc tgctggtgca
    32281 gttccgttta gtggtaagtg ttttagacta tttgacgctt gatccaattc aaagatgttt
    32341 tgttgtttgt catctccata agttccccag ttattttgca cagattggag tggagcgtat
    32401 tgtgcatcaa tccatttagc tgtcaattct aggtttttgt ttacactggt aataaccatc
    32461 ttgtcacgtg caaatcccat accgtttgta cgagctacgt gtttttgacc acttggtcca
    32521 gcaagtactg gtaaaacatc ataactttcg ttacttccag taacattatt cttatcccat
    32581 gtaaagtaaa caccaaattt ctgatcatga cctttagcaa tgtaactatt ccaatcatgt
    32641 tcgaaagctt ctttatcaat caagcctttt tcttgcaatt gacggataaa tttgacacct
    32701 tctttatagt tatcgttatc tgctgtgaag tcaactttgc catcatttcc tactactaaa
    32761 tgatcatcgt tatcccctat accaaatgca gcaaatagga atttaaaatc ttcgtttccg
    32821 ttaccactaa taaatgtaaa tggaatttca tcagcctctc catttccatt tggatccccg
    32881 tttttgaaag cttctaggac tttaatcaaa tcatcagtag tttttggcat ttcaagacca
    32941 agtttcttaa gccaatcttt gttaatccaa gccatatcgt tgacgctgtg aatagactct
    33001 ttaccatctc caagctcttc aatccatggg aatgagtaaa tgtgcccatc aggtgctgtc
    33061 atcaaggcct tgtactctgg tttctcatcc aaaattttct taagatttgg catgtattta
    33121 tcaatcaaat cttcaactgg aataataaca ccttttttag cccagttcat caagtccaca
    33181 tctgaagctc cgtcgttgtg gatagcatct ggtaaatcac cactagaaat atccaagtta
    33241 cgtttttctg caaagtcgga ttggtagttg gtccagtcaa tatgaacgcc agtttccttc
    33301 tccaaacgtt gtaaaattaa cttttcattt gggtctttag gagataacgg tgaactggct
    33361 gtcataaact tcaatgtttt cttttcttga agcgggaatg ttacaccttc caacttataa
    33421 tctggacttg aagctgtatt ttttgagcca caggctgcaa gtactgctaa actagctgtc
    33481 aacaaaactg ctgattttga gaatgttttg aatttcatga gaaaactcct tttatttttt
    33541 ctttttttat cctttaagtg aaccagccat aattccttta tcaaagtatt tttggaagaa
    33601 tggatacata acaatcaatg gcaagctgga aatgacaata gttgcgtatt taatcaattc
    33661 agctaaacgt ttcatttcat tcatagccgc ttgtgctcca atcatgtctt gacctggttg
    33721 gctctgaatg agaattttac gaagtacaag ttgcaatggt tccaagtttg gatccttgat
    33781 ataaatcatt gcatcaaagt atgagttcca ctgtcctaca aaagcataga ggaagagaac
    33841 aaacataatt ggttttgcaa gaggaagcat gattttgaag aaaatctgta aatcatttgc
    33901 accatcaatg acagcagctt caactaattc ttcaggcaat ccttggaaat aggccctagc
    33961 aagaataata ttccaaacat tgacagcacc tggaacaatg attgcccatg gagtattgag
    34021 cattcccaat tcttttacga gcaagtaagt tgggactaaa ccaccaccaa agaacatagt
    34081 tacaatcaag aagtagttaa tccaacgacg tccaaccaag tctttcttag aaagaggata
    34141 agctgtaaac acagatagca agactgttaa agctgcaaat ccaaaagagt atagtagaga
    34201 attgataaaa cctcttagaa tagattggtc actgaataca cgctgataac cttctacagt
    34261 ccaatcggct ggattaaagc taatccctct actaaccaga accttaggat ccataaagga
    34321 tgctacgacg atataaagta aaggaagcaa agtcatcaaa acgataaaga caataatgat
    34381 tttatttaag agtaagatac gtctatcaaa ttttgtatcc ataatcgaat ttttcatact
    34441 tccctcctta aattccttca ccattattca tgcgtttaac gatttggtta actgcaacaa
    34501 gcaatactac gttaatcact gcattaaaca aaccaaccgc tgttgagtaa gaatagtctc
    34561 ctgatacaag accaacttta tagacatatg tcgagataat ttcagaagtt ggcaaattta
    34621 acgatgtctg catcaagaat gctttttcat atccgacatt cataattcca cctgcagcta
    34681 aaacaaattg gataaccata ataggcttaa gagctggaat atcaatgtgc cagattcgtt
    34741 ggaagatatt ggctccatcc agtcgggctg cttctactaa ggctggatct acatttacca
    34801 atgttgccgt gtagagcgtt gaagcccagc ccattccttg ccagatacca ctaaagatgt
    34861 ataagggtct aaagaagtct ggatttgtca agaagtcagc cttcattcca aacatagaaa
    34921 gaaaattgtt gattggtcct cccactgaaa agaagaggaa aatcataccg acaataacaa
    34981 cgactgagat aaagtttggt gcgtataaaa tgagctgaat tcgttttttg actttttcac
    35041 tcaagagttg attgagcata atagcaagaa tgattggtgg taaaaagcca agcaataaac
    35101 catagatact taattttaat gtgttggcta acaagatacc aaagttggga gaggatatga
    35161 attttgtaaa ctcagaaaaa ccaatccaat cactccctaa aattcctttt aaaggattgt
    35221 aatctttaaa tgcgattaaa accccataca tagggatgta tttaaagata aaggttaaaa
    35281 ctaaaccggg gacagtcatc aataacaaga gtttttgttt cttgattctt tcccaaagag
    35341 aaacttgctt cgctttgcta ttcatagcaa cctccttttt gaaacgtttc atttttttct
    35401 agaaaagata gcgcttggcg ctgtctcttt atttcttttt tgaaacgttt catttttgtt
    35461 ttaaaaataa atctttttta tctgaattca ttctatcatt gatagcgctt tctgtcaaga
    35521 cttattttca ttttttgttg tttttccttc aacaaatttt actggtagga ttgtctgcaa
    35581 attaacagtc tttccatcaa ttatatcaaa caaaatacga accgcttctt ttgccatttc
    35641 ttccaatggt tgttcaatag ttgaaagtag ataatctcta tctccagcca ttttaattcc
    35701 atcgtatcca ataatttgga catcatgagg aatacgttta ccattttttt ctagtatttc
    35761 aatcacatcc aaagctgtaa aatcgttgat tgtaaaaatt ccatctatag aagaattttc
    35821 ttccaagaaa ctctctagct ttccataata gtcagtaact gtctcatcca aatcaaaaat
    35881 actaagaggt attttatgct cttggacata cttttcaaat gaaattctac gacgtttggt
    35941 ttcattaatg gttgtattat gtccgcccac aaaggctaaa tgctgacatc ctttactaat
    36001 taattgttta gctgcttctc ttccacctgc atcattatct gatgaaacac aaggaatggc
    36061 aatatctgag tatgtgcggt caatactaac aaagggaatt cctgacgtca agtaatgttc
    36121 aattggacta taggtaatgg caaccactcc atcaacttta ttatgacgca acatctccag
    36181 atagtcttgc tctctatttg taccattgat agaacataag agtaatttgt tatttctctt
    36241 atagacttca ttttccacat gcatagcaaa ttctgaaaag aagggatgcc agatacttgg
    36301 tacaatgatt gcaatcgttt ctgttcgatt ttttttcatt cctctagcgt agtaatctgg
    36361 aatgtaattc aaagttttaa tcgcttgttc cacttttttc aaagttactt ctttaatgcc
    36421 tttttcttta ttaattacac gtgaaacagt tccaacacta actcctgctt ctaaagcaac
    36481 atctttcatg gtaattgatt ttctttgttc taccatatta tcacctcctt tcaatatata
    36541 gtatcatgca aatgcttttt aagcaactat ttctcagtca tttttggcca gatcatttat
    36601 cccatcatga ataaaatcac tccaattagc ttttgaaaat acttcaattt tcatgtgtaa
    36661 acatctacat aaaacaggaa aagccttggt ttcatagctt ttttcgtatc ttctacaaaa
    36721 aaacaagagt tttagagggc tataaatcta gatgtacatt ttgcttaaat gattgaaggt
    36781 cttttcttaa caaaaacacc ccaaaaatta gattttttct gtctaacttt tgaggtacag
    36841 ttcaaacgcg aaatagcgtt tttttgttat ttttggttac tcatctaatc gaataaacat
    36901 catggcattt aacaaatata tgagtgagac cgtgtttata ttatttgaat agatgagtct
    36961 cttattttca ataggaggaa taataaaatt ggaaataatg atatcataag gtgaatcttc
    37021 taaagattcc tttgataatt ctaattcggt ccaaacttcc agttcaaaat tattgctaca
    37081 gtaataagaa agtgtctctg caacgaattt tgcatgatac tgatcaaaat tactcataac
    37141 caaaaccttt agtttaggct gattttgtag caaattaatc accaaatgtt tggtatgagt
    37201 gatgaaggta taagatagat gatttaccat cattgaacta gaacaaacct caagagtctc
    37261 taaatagtga gaaatctctt tttttatatc tgaaacaaat tttggaaaaa tattttgaaa
    37321 gttcctgatt gtattccctt tttgatcaaa taaaataaac tcagtaaaca actcttgacg
    37381 atacagatgt gcggtattat gcagatgcca aatcagatta tccttattct ccatttcaat
    37441 ctgatacttg actgaaatct gatcaataaa atcactcaat agatggtaag atttttcaac
    37501 ataactatcc ttttttacgc atttcataaa gagactttca tctatgaaaa acattttttg
    37561 aaagtaagac acaaataatt ggcaaacaac ttcttcatct aaagagatat tgtattctga
    37621 ttcaaaactc tgagcaacac cttctattcc ttctgcctgc attaaaaaat ccaaactttg
    37681 gtcgttaaaa gaatctttat ctacttccat aaaatgacca aactttattc tatataggtt
    37741 cgtaactagg agcaacttta gcattctatg cgttgacaaa ttcattggaa agcttgtttc
    37801 cttataaacc aattctaaca attgagatag tggctctgat gaaaaatttt caaatggcca
    37861 ttctaggaaa taatattttt ctgaaaaata ttgtgcaaaa aagtaacgaa tgtctctctc
    37921 atttccaatg atttgaacag gggtcagact gacttcaaat tgaaattgcc ttttaatcac
    37981 tttattgatt tggctaataa tacgatagag cgaagatgaa ctgatataaa attctttaca
    38041 aatactctca gcttgacaac cttcattaaa gaagatgaat tctaaaatcg aaaaatgagt
    38101 tgaatgttta aagaaatgat ggtaaaccat ttcaatatca ctatcatcgg tattaataat
    38161 gcgtatacca ttagtagaag aatgaaaaat caagtcagga aaagcagatt taacatggga
    38221 tagatcatct ttgactgcac gttctgtaca atttaataac tctgctagtt cagaacgatg
    38281 aaaccaacgt ttatgttcaa ataataattc taataattct aattgcctat gacttttttt
    38341 agataataaa tctctcatga atatctttct ctctttataa attatcggat taaacctctt
    38401 gcaattatac cacaaagaat aggtatagca tgatataacg acttttccta aaatctttta
    38461 tttcgtataa taacactacg gagacaatat ataaacaatt ttcttatttt accgtctatt
    38521 gaggg
//
LOCUS       DAVLGK010000018        35644 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLGK010000018 DAVLGK010000000
VERSION     DAVLGK010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35644
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.018"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(1..302)
                     /locus_tag="VXE01_001008"
                     /pseudo
     CDS             complement(1..302)
                     /locus_tag="VXE01_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            312..552
                     /locus_tag="VXE01_001009"
                     /pseudo
     CDS             312..552
                     /locus_tag="VXE01_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
     gene            797..2131
                     /gene="trmFO"
                     /locus_tag="VXE01_001010"
     CDS             797..2131
                     /gene="trmFO"
                     /locus_tag="VXE01_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV0749928.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2215..2952
                     /locus_tag="VXE01_001011"
     CDS             2215..2952
                     /locus_tag="VXE01_001011"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV0749929.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2961..3518
                     /gene="frr"
                     /locus_tag="VXE01_001012"
     CDS             2961..3518
                     /gene="frr"
                     /locus_tag="VXE01_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV0749930.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3578..4432
                     /gene="cvfB"
                     /locus_tag="VXE01_001013"
     CDS             3578..4432
                     /gene="cvfB"
                     /locus_tag="VXE01_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV0749931.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4441..4656
                     /locus_tag="VXE01_001014"
     CDS             4441..4656
                     /locus_tag="VXE01_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV0749932.1"
                     /translation="MRKSFYIWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4742..5710
                     /locus_tag="VXE01_001015"
     CDS             4742..5710
                     /locus_tag="VXE01_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV0749933.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(5688..5867)
                     /locus_tag="VXE01_001016"
     CDS             complement(5688..5867)
                     /locus_tag="VXE01_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749934.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            5903..6403
                     /locus_tag="VXE01_001017"
     CDS             5903..6403
                     /locus_tag="VXE01_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0749935.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            6406..6665
                     /locus_tag="VXE01_001018"
                     /pseudo
     CDS             6406..6665
                     /locus_tag="VXE01_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(7032..7358)
                     /locus_tag="VXE01_001019"
     CDS             complement(7032..7358)
                     /locus_tag="VXE01_001019"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749936.1"
                     /translation="MVDLAVDQGGLIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(7304..7717)
                     /locus_tag="VXE01_001020"
                     /pseudo
     CDS             complement(7304..7717)
                     /locus_tag="VXE01_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810031.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7718..8143)
                     /locus_tag="VXE01_001021"
     CDS             complement(7718..8143)
                     /locus_tag="VXE01_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV0749937.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYFRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVADRMAV"
     gene            8320..8889
                     /locus_tag="VXE01_001022"
     CDS             8320..8889
                     /locus_tag="VXE01_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0749938.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8957..9607
                     /locus_tag="VXE01_001023"
     CDS             8957..9607
                     /locus_tag="VXE01_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV0749939.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            9591..11831
                     /locus_tag="VXE01_001024"
     CDS             9591..11831
                     /locus_tag="VXE01_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV0749940.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FFQFPWKSASKVLVICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGEKLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTIKEGKGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKGSLKQKQFVVELQATKTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            12230..12817
                     /locus_tag="VXE01_001025"
     CDS             12230..12817
                     /locus_tag="VXE01_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749941.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRFYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12821..13996
                     /locus_tag="VXE01_001026"
     CDS             12821..13996
                     /locus_tag="VXE01_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749942.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEAKLSQMSDTSSEEYQFAKSNLELQKNLLKRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIIWILEAIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAMSS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVKQEVTIGKMQDVLFPS
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQKIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    14170..14301
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14317..14847
                     /gene="infC"
                     /locus_tag="VXE01_001027"
     CDS             14317..14847
                     /gene="infC"
                     /locus_tag="VXE01_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV0749943.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14880..15080
                     /gene="rpmI"
                     /locus_tag="VXE01_001028"
     CDS             14880..15080
                     /gene="rpmI"
                     /locus_tag="VXE01_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV0749944.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15132..15491
                     /gene="rplT"
                     /locus_tag="VXE01_001029"
     CDS             15132..15491
                     /gene="rplT"
                     /locus_tag="VXE01_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV0749945.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15549..15929
                     /locus_tag="VXE01_001030"
     CDS             15549..15929
                     /locus_tag="VXE01_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0749946.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16179..16979
                     /locus_tag="VXE01_001031"
     CDS             16179..16979
                     /locus_tag="VXE01_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV0749947.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGHVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPENETVSQRVCEDGPVFRTGTVVL"
     gene            16990..17928
                     /locus_tag="VXE01_001032"
     CDS             16990..17928
                     /locus_tag="VXE01_001032"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV0749948.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSTEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17970..20135
                     /gene="lytB"
                     /locus_tag="VXE01_001033"
     CDS             17970..20135
                     /gene="lytB"
                     /locus_tag="VXE01_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0749949.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFY
                     LKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNENAA
                     YYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQ
                     ALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLE
                     NPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHS
                     ALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGR
                     TFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(20196..21851)
                     /gene="pavA"
                     /locus_tag="VXE01_001034"
     CDS             complement(20196..21851)
                     /gene="pavA"
                     /locus_tag="VXE01_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV0749950.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSIFQGLGRDTANELERILVSEK
                     FSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLETDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21956..22453
                     /gene="ybeY"
                     /locus_tag="VXE01_001035"
     CDS             21956..22453
                     /gene="ybeY"
                     /locus_tag="VXE01_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV0749951.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22434..22829
                     /locus_tag="VXE01_001036"
     CDS             22434..22829
                     /locus_tag="VXE01_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV0749952.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22846..23745
                     /gene="era"
                     /locus_tag="VXE01_001037"
     CDS             22846..23745
                     /gene="era"
                     /locus_tag="VXE01_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV0749953.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23794..24618
                     /gene="mutM"
                     /locus_tag="VXE01_001038"
     CDS             23794..24618
                     /gene="mutM"
                     /locus_tag="VXE01_001038"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV0749954.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24618..25223
                     /locus_tag="VXE01_001039"
     CDS             24618..25223
                     /locus_tag="VXE01_001039"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV0749955.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            25210..26409
                     /locus_tag="VXE01_001040"
     CDS             25210..26409
                     /locus_tag="VXE01_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV0749956.1"
                     /translation="MTEINWKDNLRIAWFDNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26409..26558
                     /gene="rpmG"
                     /locus_tag="VXE01_001041"
     CDS             26409..26558
                     /gene="rpmG"
                     /locus_tag="VXE01_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0749957.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26598..26831
                     /gene="secG"
                     /locus_tag="VXE01_001042"
     CDS             26598..26831
                     /gene="secG"
                     /locus_tag="VXE01_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV0749958.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26933..29287
                     /gene="rnr"
                     /locus_tag="VXE01_001043"
     CDS             26933..29287
                     /gene="rnr"
                     /locus_tag="VXE01_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV0749959.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKYSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTQ"
     gene            29250..29717
                     /gene="smpB"
                     /locus_tag="VXE01_001044"
     CDS             29250..29717
                     /gene="smpB"
                     /locus_tag="VXE01_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV0749960.1"
                     /translation="MAKGEGKVVAHNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29733..30593
                     /gene="tehB"
                     /locus_tag="VXE01_001045"
     CDS             29733..30593
                     /gene="tehB"
                     /locus_tag="VXE01_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV0749961.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30666..31619
                     /gene="coiA"
                     /locus_tag="VXE01_001046"
     CDS             30666..31619
                     /gene="coiA"
                     /locus_tag="VXE01_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV0749962.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            31638..33440
                     /gene="pepF"
                     /locus_tag="VXE01_001047"
     CDS             31638..33440
                     /gene="pepF"
                     /locus_tag="VXE01_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0749963.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLIHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            33442..34155
                     /locus_tag="VXE01_001048"
     CDS             33442..34155
                     /locus_tag="VXE01_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV0749964.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQRLFDATLDNSELTATLVPLG
                     DGILMLRKNVADVQLPDSE"
     gene            34222..35163
                     /gene="prsA"
                     /locus_tag="VXE01_001049"
     CDS             34222..35163
                     /gene="prsA"
                     /locus_tag="VXE01_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV0749965.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(35280..35621)
                     /locus_tag="VXE01_001050"
                     /pseudo
     CDS             complement(35280..35621)
                     /locus_tag="VXE01_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        10728 a         6613 c         8011 g        10292 t
ORIGIN      
        1 gaaatcgtaa caccactttg aacaagagtt acttcaaccc attggctccg acggattaag
       61 ttgctttcgt ggataccaaa atcagccgca atttcttcat aagttcaata ttctcgcaca
      121 tattgaagag tggccataag aaggtcttct aggcttaatt taggttttcg tccacctttt
      181 gcgtgtttaa gttgataagc tgtttttaat acagctaaca tctcttcaaa agtggtacgc
      241 tgaacaccaa caagacgctt aaatcgtgta tcagttaatt gtttacttgc ttcataattc
      301 atagaactac tataccatat tttgtttcgc aggaagtcta ttggaaagta agaaatattg
      361 aagctgaggc tattagaaga aattgtgagc gtggtgctat tttttcaggt aaaaataaaa
      421 tatcacgaag attcacagtt taaaggagat cactatgttg aatgttatgc tgttttagat
      481 aatacggtta tagcaagaga tagaataaca gtccctatcg atccgttatg tggaaaagat
      541 tttatagagt agcatataat tgattcttaa ctggaatact cactatctct ttacatcaag
      601 aaaatgacta aacagggaag tttgccttct tccctttttt tgttatacta gtagaagaaa
      661 aaatagaaag atttgtggga gtgaaaaagt cctgtggact ttttcagcct gagccaagaa
      721 actcgaaagc tcgtaagtct gattggcttt ttcaatgtga atcttaactt cacactccca
      781 aagaggtatt agtgtcgtgt ctcaatctta tatcaatgtt atcggtgctg gtttggcagg
      841 ttctgaagca gcttaccaaa tcgcagagcg tggtattcca gttaaacttt atgaaatgcg
      901 tggtgtcaag tcgactcctc agcataaaac agacaatttt gctgagttgg tttgttccaa
      961 ttctttgcgt ggggatgctt tgacaaatgc agttggtctt ctcaaggaag aaatgcgtcg
     1021 cttgggttct gttatcttgg aatctgctga ggctacacgt gttcctgccg gtggagccct
     1081 tgcggtggat cgtgatggtt tctcccaaat ggtaaccgaa aaagtggtca accacccctt
     1141 gattgaagtg gtgcgtgatg aaattacaga attgccaaca gatgttatta cagttgtggc
     1201 gaccggtccc ttgactagcg atgccctggc tgaaaagatt catgccctta atgatggcga
     1261 tggcttctat ttctacgatg cagcagcgcc tattatcgat gtcaacacta tcgatatgag
     1321 taaggtctat ctcaaatctc gttatgataa gggagaagca gcctatctca atgctccaat
     1381 gaccaagcaa gagtttatgg atttccatga agccttggtc aatgcggaag aagcaccgct
     1441 caattctttt gaaaaagaaa agtactttga aggatgtatg ccaatcgaag ttatggccaa
     1501 acgtggcatt aaaactatgc tttatggccc tatgaagcca gtcggtcttg agtatccgga
     1561 cgactacaca ggacctcgtg atggagaatt taaaacacct tatgcggttg tgcaacttcg
     1621 tcaggataat gcagctggta gcctctacaa tatcgttggt ttccagaccc acctcaaatg
     1681 gggagaacaa aagcgtgtct tccaaatgat tccgggtctt gaaaatgcgg agtttgtccg
     1741 ttatggtgtc atgcatcgca attcttacat ggattcacca aatcttcttg agcagactta
     1801 ccgttccaag aaacaaccaa atctcttctt tgctggtcag atgacggggg tggaaggcta
     1861 tgttgagtcg gcggcttcgg gcttagttgc gggaattaac gcagctcgtc tcttcaagga
     1921 agaaagcgag gttattttcc ccgagacgac agcgattgga agcttagctc attacattac
     1981 ccatgccgac agcaaacatt tccaaccaat gaatgtcaat tttgggatca tcaaggagtt
     2041 ggaaggcgag cgtatccgtg ataagaaggc tcgttatgaa aaaattgcag agcgtgccct
     2101 tgccgactta gaggaatttt tgactgtcta atttttttga aagaattgct catgatacta
     2161 taaaaatctt agaaattgtg ataaaatagg taggatgaaa gaaggagagt gaaaatggcg
     2221 aatcccaagt ataaacgtat tttaatcaag ttatcaggtg aagcccttgc cggtgaacgt
     2281 ggcgtaggga ttgatatcca aacagttcaa acaatcgcaa aagagattca agaagttcat
     2341 agcttaggta tcgaaattgc ccttgttatt ggtggaggaa atctctggcg tggagaacct
     2401 gcagcagaag caggtatgga ccgtgttcag gcagattaca ctggaatgct tgggactgtt
     2461 atgaatgctc ttgtgatggc agattcattg caacaagttg gggttgatac gcgtgtacaa
     2521 acagctattg ctatgcaaca agtggcagag ccttatgtcc gtggacgtgc ccttcgtcac
     2581 cttgaaaaag gccgtatcgt tatctttggt gctggaattg gttcaccata cttctcgaca
     2641 gatacaacag cggcccttcg cgcagctgaa atcgaagcag atgccatcct catggctaaa
     2701 aatggcgtcg atggtgtgta caatgccgat cctaagaagg acaagacagc cgttaagttt
     2761 gaagaattga cccaccgtga tgttatcaac aaaggtcttc gtatcatgga ctcaacagcc
     2821 tcaaccctct caatggacaa cgacattgac ttggttgtct tcaacatgaa ccaatcaggc
     2881 aacatcaaac gtgtcgtatt tggtgaaaat atcggaacaa cagtttcaaa taatatcgaa
     2941 gaaaaggaat aagaaagaat atggctaacg taattattga aaaagctaaa gagagaatga
     3001 cccagtctca ccaatcactt gctcgtgaat ttggtggtat ccgtgctggt cgtgccaatg
     3061 caagcttgct tgaccgtgta catgtagaat actatggagt cgaaactcct cttaaccaaa
     3121 tcgcttcaat tacgattcca gaagcgcgtg ttttgttggt aacaccattt gacaagtctt
     3181 cattgaaaga catcgaacgt gccttgaacg cttctgatct tggtatcaca ccggctaatg
     3241 acggttctgt gattcgcttg gttatcccag ctcttacaga agaaactcgt cgtgaccttg
     3301 ctaaagaagt gaagaaggtc ggcgaaaatg ctaaagtggc tgtccgcaat atccgtcgcg
     3361 atgctatgga cgaagctaag aaacaagaaa aagcaaaaga aatcactgaa gacgaattga
     3421 agactcttga aaaagatatt caaaaagtaa cagacgatgc tgttaaacac atcgacgaca
     3481 tgactgctaa caaagagaaa gaacttttgg aagtctaaaa ataaacagaa aaactcagtt
     3541 ggcattgctg gctgagtttt attcgaaaga aggaaatatg aatacaaatc ttgcaagttt
     3601 tatcgttgga ctgatcatcg atgaaaatga ccgtttttac tttgtgcaaa aggatggtca
     3661 aacctatgct cttgctaagg aagagggcca acatacagta ggggatacgg tcaaaggttt
     3721 tgcatacacg gatatgaagc aaaaactccg cctgacaacc ttagaagtga ctgccactca
     3781 ggaccaattt ggttggggac gtgtcacaga ggttcgtaag gacttgggtg tctttgtgga
     3841 tacaggcctt cctgacaagg aaatcgttgt gtcactcgat attctccctg agctcaagga
     3901 actctggcct aagaagggcg accaactcta catccgtctt gaagtggata agaaagaccg
     3961 tatctggggc ctcttggctt atcaagaaga cttccaacgt cttgctcgtc ctgcttacaa
     4021 caacatgcag aaccaaaact ggccagccat tgtttaccgt ctcaagctgt caggaacttt
     4081 tgtttaccta ccagaaaata atatgcttgg ttttattcat cctagcgagc gttacgcaga
     4141 gccacgtttg gggcaagtat tagatgcgcg cgttattggt ttccgtgaag tggaccgcac
     4201 tctgaacctc tccctcaaac cacgctcctt tgaaatgttg gaaaacgatg ctcagatgat
     4261 tttgacttat ttggaaagca atggcggttt catgacctta aatgacaagt catctccaga
     4321 cgacatcaag gcaacctttg gcatttctaa aggtcagttc aagaaagctt taggtggtct
     4381 tatgaaggct ggtaaaatca agcaagacca gtttgggaca gagttgattt agggaggctt
     4441 atgagaaaat cattttacat ttggctcatg accgagcgca atcctaaaag taacagtccc
     4501 aaagcaattt tggcagacct cgcttttgaa gagtcagcct ttccaaaaca tacagatgat
     4561 tttgatgagg tcagtcgctt tttggaggag catgccagtt tctcttttaa cctaggagat
     4621 tttgacagca tttggcagga atatctagaa cactagcatt tattcattgg gtttgggcta
     4681 gtaatttctc catccctctg ctataataaa aagaaataaa aggattagag aggttcttta
     4741 tttgaaggaa cattcaatag acattcaact gagtcatcca gatgacctgt ttcatctttt
     4801 tggttccaat gaacgccatc ttcgtttgat ggaagaagag cttgatgttg tgattcatgc
     4861 tcgtacggag attgtccagg ttttgggaga agagtctgct tgcgaggaag cccgtcaggt
     4921 tattcaagct ctcatggcct tggtaaatcg tgggatgacc gttggtacgc cagatgtagt
     4981 gacggctatt agtatggtca aaaatgatga aattgacaag tttgtcgccc tttacgaaga
     5041 agaaatcatc aaggataata ctgggaagcc tatccgcgtc aaaaccttag gtcaaaaact
     5101 ttatgtggac agtgtcaaac agcatgatgt gacctttgga attgggccgg caggtacagg
     5161 gaagaccttc cttgcagtga ccttggcagt gactgccctt aaacgtgggc aagtcaagcg
     5221 aattatccta actcgtccag cggtggaagc gggagagagt cttggatttc ttccgggtga
     5281 tcttaaggag aaggtggatc cttaccttcg tcctgtttac gatgccttgt atcaaattct
     5341 tgggaaagac caaacgactc gtctcatgga gcgtgaaatt atcgaaattg cgccccttgc
     5401 ctatatgcgt ggccggacct tggatgatgc ctttgtcatt ctcgatgagg cgcaaaacac
     5461 gaccatcatg cagatgaaga tgttcttgac gcgtttaggc tttcattcta agatgattgt
     5521 caatggagat atcagtcaga ttgacctgcc acgtaatgtc aagtccggtt tgattgatgc
     5581 tcaagagaaa ctcaagaaca tccatcagat tgactttgtt catttttcag ctaaggatgt
     5641 ggttcgccat ccagttgtcg ctcaaattat ccgagcctat gaatattcta ctgaagttgc
     5701 acacgactga ttttgaggaa gttcgcctgc aaaagaatat acttttgaga gaggaaaatc
     5761 cagttgtata ggctaaaggt tttatccaaa ggtttgagac aacgattagg cacgatggaa
     5821 agaactttta tgtggctgat gacgatcagt gcatcttcct gtgtcataat cacagggaac
     5881 aagaaagtag gaatttgaaa agatgattga ccaactatct aagtattaca gttgtaggat
     5941 actaactgaa aaggatattc caagtatttt atctttatat gaaagtaatc ctctgtattt
     6001 tcagcattgt ccaccagagc caaattttgc aactgtaaaa gaggacatgc tttgtctacc
     6061 tgaaggtaaa gctaaggctg ataagttttt tgttggattt tggaatggct ctgaccttgt
     6121 ggctgttatg gattttgtct atgcatatcc tgatgaggag actgttttta ttggtttgtt
     6181 tatggttgat caagcctatc agaggaaagg gattggtagt catattgtga cagaagcact
     6241 agcttatttt gctaagaact ttcgaaaggc acgtttggct tatgttaagg gaaatccgca
     6301 atctcagcat ttttgggaaa agcagggctt taaatcaatt ggatgcgagg ttaagcaaga
     6361 actctatacg gttgttatcg ttgaacagag cctagaagat tagaaatggc atcaagtaag
     6421 aactatttgg aatttgtttt ggaacaatta tcaggattag atgatgtgac ttaccgttcc
     6481 atgatggggg agtatattct ttacttccgc ggcaagatta ttggcggtat ttatgacgat
     6541 cgcttttagt taaacccgtg caagcagtct tagataagat tgaccaatct tcttttgagt
     6601 ttccatacaa aggtgccaaa gaaatgattt gagtggaaga acttgataat aagatgtttc
     6661 tataagacct gattttagct atgtataacc aactgccaac gcccaaacct aaaaagaaaa
     6721 agcaagggtg aacgaagtaa aaaagaagtc tgctaaggcc ctgtctttgc acgggtaaaa
     6781 ttttatatat aaaaagaagc tgggactaaa gagctcagct tcctttggtt tatataattg
     6841 tcattacaag acgaagtggt tgggcgaaac tctgttgact ttattcaatt tagagtttct
     6901 tatgcacaat tgagtctgga acgaaagtct ccagttgcaa agtatacagt acaataaacc
     6961 aacgatgtaa tagctgatga cacaaagcac agtgggtagg acttgcgaag tcaccctttt
     7021 cttttcaaaa tttatactaa atcattgata tcagtgtagt cacgattaag tccttgagca
     7081 actggtaggc tagtcaagta accttgataa gtggtcacac cttgacgcaa gccttcatct
     7141 tcagagattg cttgtgcgaa tcctttgcca gccaaagctt cgatataagg aagagtgaca
     7201 ttggttaggg cgatggttga agtgcgagca accgcaccag ggatattggc aacggcatag
     7261 tggagaacac cgtgtttttc atagacgggt tcatcgtgcg ttgtcacacg gtcagctgtt
     7321 tcgataaggc caccttggtc aacagcaagg tcaacgatac agagcctgga cgcatttgtt
     7381 tgaccatctc atctgtcacc aattccggtg cttttgcacc agggatgaga atggctccaa
     7441 tcaccacatc agcatctctc acacttgctt caatgttgaa tgaattagat ataagagttt
     7501 aaatttgact tccaaagact tcttttagaa ctgagagacg cttggcacta atatctaaaa
     7561 tagtcacttg agcaccaaga ccaagggcga tgcgggcagc atgtgtactg acgacaccat
     7621 caccgatgat agttactttt ccttttggaa cacctggtac accaccaggt agaacaccag
     7681 agccaccagc ttgcttagta aggaagtgag ctccgattta aacagccata cgatctgcaa
     7741 cctcactcat aggaacgagg agcggtagtt gtccttgatt gtcacgaaca gtttcatagg
     7801 caattcctgt tgtttttgct gctaacatag catctgctaa ttctggagca gcggccatgt
     7861 gcaagtaggt gaagagaaga agatcgtcgc gaaagtaacc gtattcagaa cttaaaggtt
     7921 cttttacttt cacaaccaac tctgctgccc aagcttcacc agcagtagcg acaatctcag
     7981 ctccttgctt ttgatagtca gcatcagtaa agccagaacc gagaccagca tttgtttcga
     8041 taaggacacg atgaccacga ctaactaagc tatgaacacc tgcaggtgtg agggcgacac
     8101 ggttttcgtt atttttaatt tcttttggga ttccgattaa cattgagata acctaccttt
     8161 caattgacgg tcttgttttg gttgtcacat tccagttcat aaatcaaaaa tgtgacggtt
     8221 tcattgtata tgaaaccgct tcaaaaatca agaaaaactt gtcatccaaa ttttttatgc
     8281 tagactagtg aaaatcaagc tttgattggt tggaaaagta tggaatcaat ttttgtaaaa
     8341 cttgcccagt atccgtctat agaaacggag cgtttattgc ttagacctgt aactttggat
     8401 gatgcggaag caatgtttga ctatgcctcg gacaagggta atacacgtta cacttttcca
     8461 accaatcaaa gtttggaaga aaccaagaat aacattgctc agttctattt ggctaatccc
     8521 ttgggacgtt ggggaataga actaaaaagc aatggtcagt ttattggaac cattgacttg
     8581 cacaagattg attctgttct taagaaggca gctattggct acattatcaa taaaaagtat
     8641 tggaatcaag gattaacgac agaagccaat cgtgctgtga ttgagctagc ttttgagaag
     8701 atagggatga ataagttgac tgcccttcac gataaggaca atcctgcgtc aggaaaggtc
     8761 atggagaaat caggcatgcg tttttcccat gcagaaccat atgcttgtat ggaccagcat
     8821 gaaaaaggcc gaatcgtgac aagagttcat tatgtcttga ccaaggaaga ctattttgca
     8881 aataaataag cagttgaaaa gaaatttttc gactgttttt tcttcctctt acgaataatc
     8941 taagagagga gaaaatatgg aagcaattat cgagaaaatc aaagagtata aaatcatcgt
     9001 catctgtact ggtctgggct tgcttgtagg aggatttttc ctgctaaaac cagctccaca
     9061 aacacctgtc aaagagacga atttgcaggc tgaagtcgca gctgtttcca aggatttggt
     9121 atccgaaaag gaagtgaaca aggaagaaaa ggaagaaccc cttgaacaag atctaatcac
     9181 agtagatgtc aaaggtgctg tcaaatcgcc agggatttat gacttgcctg taggtagtcg
     9241 agtcaatgat gctgttcaga aggctggtgg cttgacagag caagcagaca gcaagtcgct
     9301 caatctagct cagaaagtta gtgatgaggc tctggtttac gttcctacta agggagaaga
     9361 agcagttagc caacagactg gtttggggac agcttcttca ataagcaagg aaaagaaggt
     9421 caatctcaac aaggccagtc tggaagaact caagcaggtc aagggactgg gaggaaaacg
     9481 agctcaggac attatcgacc atcgtgaggc aaatggcaag ttcaagtcag tagacgagct
     9541 caagaaggtc tctggcattg gtggcaaaac aatagaaaag cttaaagact atgttacagt
     9601 ggattaagaa tttctctatt cccctaattt acctgagttt tctgttactt tggctttact
     9661 acgctatttt ctcagcatcc tatcttgctt tgttgggatt tgtttttctg ctagtctgtc
     9721 tctttttcca atttccttgg aaatctgcta gcaaagttct agtgatttgt ggaatctttg
     9781 gattttggtt tgtttttcaa aattggcaac agagtcaagc gagtcaaaat ctggcggatt
     9841 ctgttgaaag ggtacggatt ttgcctgata ctattaaggt caatggtgat agtctatcct
     9901 ttcgtggcaa gtctaacggt cgtgctttcc aagtctatta taaactccag tccgaggagg
     9961 agaaagaagc ctttcaagct ttaaccgacc tgcatgagat aggactagaa gggaagcttt
    10021 cggagccaga agggcagaga aattttggtg gctttaatta ccaagcctat ctgaagactc
    10081 agggaattta ccagacactc aatattaaaa gaatccagtc actccaaaag gttggcagtt
    10141 gggatatagg tgaaaaactg tccagtttac gtcgaaaggc tgtggtttgg attaagatgc
    10201 acttcccaga ccctatgcgc aattacatga caggactctt gctaggacat ctggacaccg
    10261 attttgagga gatgaatgag ctttattcca gtttaggaat tattcacctt tttgccttgt
    10321 caggtatgca ggtagggttt ttcatgaatg gatttaagaa acttctcttg cgattgggct
    10381 tgacccaaga aaagttgaaa tggctgactt atcccttttc ccttatctat gcgggactaa
    10441 ctggattttc agcatcggtt attcgcagtc tcttgcaaaa gctactggct caacatgggg
    10501 ttaagggctt ggataatttt gccttgacgg tgcttgtcct ctttattgtc atgccaaact
    10561 ttttcttgac agcaggagga gtcttgtcct gcgcttatgc ttttatcctg accatgacca
    10621 ttaaagaagg gaaggggctc aaggctgttg ctagtgaaag tctagtcatc tccttgggca
    10681 tattgcccat tctatccttc tattttgcgg aatttcaacc ttggtctatc cttttgacct
    10741 ttgtcttttc ctttctattt gacttgacct tcttaccgct cctgtctatt ttatttgtcc
    10801 tttcctttct ctatccagtc attcagctga actttatctt tgaatggttg gagggcatta
    10861 ttcgcttggt ctcacaggtg acaagtaggc ctctagtctt tggacaaccc aatgaatggc
    10921 ttttaatcct attgttaatt tctttggctt tggtctatga tttgaggaaa aacattaaag
    10981 gattaacagt attgagttta ttgattacag gtctcttttt cttgaccaag tatccactgg
    11041 aaaatgaaat caccatgctg gatgtggggc aaggagaaag tattttccta cgggatgtaa
    11101 ctgggaaaac cattctcata gatgtaggtg gtaaggcaga atcttataag aaaatcgaaa
    11161 aatggcaaga aaagatgacg accagcaatg cccagcgaac cttgattccc tatctcaaaa
    11221 gtcgaggagt agctaagatt gaccagctaa ttttgactaa cacggacaag gagcatgttg
    11281 gagatttgtc agaggtgacc aaggctttcc atgtagggga gattttagta tcaaaaggca
    11341 gtttgaagca gaagcaattt gtggtagaac tacaggcgac taaaacaaag gtgcgtagta
    11401 tgacagtagg ggagaacttg cccatttttg gaagtcagtt agaagttcta tctccaagga
    11461 aaatgggaga tggaggacac gatgataccc tagttctgta tgggaaattc ttggataagc
    11521 aatttctctt cacgggaaat ttggaggaga aaggagagaa ggacttgctg aagcactatc
    11581 cagacttgaa agtaaatgtt ttgaaagcta gccaacatgg caataaaaaa tcatcaagcc
    11641 cagcctttct agaaaaactc aaaccagagc ttactcttat ctcagttgga aagagcaatc
    11701 gaatgaaact cccccatcag gaaacattga cacgactgga aggtatcaat agcaaagttt
    11761 atcgaactga ccagcaagga gctatacgtt ttaaggggtt ggatagttgg aaaatcgaaa
    11821 gtgttcgata ggaaagataa atgttgtaga ttagtgaaat aaactaaaaa tttgttgcat
    11881 aataatgata aaaatggtat aatgaaaacg tattcaatat tgaggatata aaatcattaa
    11941 aaatcagcaa aagttatttt attagttagt ttataatcta ttggtcttct tcagtccagt
    12001 gtatctgcta agagtgttct taaaagtatc ggtatgattg gaatatcttc tataagtcta
    12061 gtatgaattt ccatggatat agacatacta acgttccgtc atggtctcgt tattacagct
    12121 attctgagta tccagttggt tctggctgga actacggtcg ttatgagatc ataaactatt
    12181 acagcggagg ctattaattc ttaaagagtg agaaaaagga gggctagata tgttgcagct
    12241 tactcatgtg accttaaaaa cgcgacaagt catcttgcaa gatgcggatt tcacctttaa
    12301 aaagggtagg ttttatggtc ttcttgctat caatggctct ggaaagacga ccctgttccg
    12361 tgccattagc aatttaattc ccataagtag tggaaatatc gcagcccctc cttctttatt
    12421 ttattatgag agtattgaat ggctggatgg aaacttaagt gggatggact accttcgtct
    12481 tatcaaaaac atctggaagt cagacctaaa cttgagagat gaaatcgcct actgggaaat
    12541 ggctgactat atcagtcttc ccatccgcaa gtattcctta ggcatgaagc aacgcttggt
    12601 gattgctatg tattttctca gtcaggcaaa atgctggctc atggatgaga ttacaaatgg
    12661 cttagacgag tattatcgac agaagttttt tgataggcta gcacaaatcg atagacaaga
    12721 acagctggtt cttttaagtt cccactataa ggaagagttg gttgatatct gcgatagagt
    12781 agtaaccatt catcaggggc agatagaaga ggtttagttt atgaaagatg ttagtctatt
    12841 tttattgaaa aaagttttca aaagtcgttt aaactggatt atcttacttt tatttgcatc
    12901 tgtactcggt gttacctttt atttaaatag tcagactgca aactcacaca gcttggagag
    12961 caggttggaa agtcgcattg cagccaacga gagagccatc aatgaaaatg aagcgaaact
    13021 ttcccaaatg tctgacacca gctcggagga ataccagttt gctaaaagta atttagaatt
    13081 gcaaaaaaat cttttgaagc gaaagacaga aattctgact ttattaaaag aagggcgctg
    13141 gaaagaggcc tactatctgc agtggcaaga tgaagagaag aattatgaat ttgtatcaaa
    13201 tgacccgact gctagctctg gcttaaaaat gggggttgac cgcgaacgga agatttacca
    13261 agccctgtat cccttgaaca taaaagcaca tactttggag tttccgaccc acgggattga
    13321 tcagattatc tggattttag aggctatcat cccaagcttg tttgtggttg ctattatttt
    13381 tatgctaaca caactatttg cagaaagata tcaaaatcat ctggacacag ctcacttata
    13441 tcctgtttca aaagtgacat ttgcaatgtc ttctcttgga gttggagtgg gctatgtaac
    13501 tgtgctgttt atcggaatct gtggcttttc ttttctagtg ggaagtctga taagtggttt
    13561 tggacagtta gattatccct acccgattta tagcttagtg aaacaagagg taactattgg
    13621 aaagatgcag gatgtattat ttcctagctt gctcttagct ttcttagcct ttatcgtcat
    13681 tgtggaagtt gtgtatttga ttgcttactt tttcaagcaa aaaatgcctg tcctctttct
    13741 ttcactcatt gggattgttg gcttattgtt tggcatccaa accattcagc ctcttcaaaa
    13801 gattgcacat ctgattccct ttacttactt gcgttcagtg gagattttat ctggaagatt
    13861 acctaagcag attgataatg tcgatctaaa ttggagcatg ggaatggtct tacttccttg
    13921 cctgattatc tttttgctat tgggaattct atttattgaa agatggggaa gttcacagaa
    13981 aaaaagaatt ttttaataga ttctagcttt cctataggta gggaaaataa gtaaaaacta
    14041 acatagagag ggaatcaact tgattctctc tttttgattt gaaaaccaaa ccaaaataca
    14101 aacacaaact tttcaaaaaa taacttttta tcttgacaag agctagaaaa cttggtatca
    14161 tataaaagtt gagaaaagca gaagtgagag cttctcgcct tgtgacatta agttgcctgg
    14221 ccctacggat gaaaagtttc gaagaaacgc tatcataacg tgcgggcttg tatatttacg
    14281 agtccgctat tgtttttctc taataaaaca aaagaggtga aaaccatagc aaagcaagac
    14341 ttattcatca atgatgagat tcgtgtacgt gaagttcgct tgattggtct tgaaggagaa
    14401 cagctaggca tcaagccact cagtgaagcg caagctttgg ctgataacgc taatgttgac
    14461 ctagtattga ttcaacccca agccaaaccg cctgttgcaa aaattatgga ctacggtaag
    14521 ttcaaatttg agtaccagaa gaagcaaaaa gaacaacgta aaaaacaaag cgttgttact
    14581 gtgaaagaag ttcgtctaag tccaactatt gacaagggtg actttgatac aaaacttcgt
    14641 aatgcacgta agttccttga aaaaggaaat aaagttaagg tatctattcg ctttaagggt
    14701 cgtatgatta cccataaaga gattggtgca aaagttttag ccgagtttgc tgaagcaact
    14761 caagatattg ccatcatcga acaacgtgct aaaatggatg gacgtcaaat gttcatgcaa
    14821 ttggcgccag cgactgacaa aaaataattg tcagaaagtt aaataaagga gaaaaaatca
    14881 tgccaaaaca aaaaacacac cgcgcatcag ctaaacgttt caaacgtaca ggttctggtg
    14941 gacttaaacg tttccgtgct tacacttctc accgtttcca cggaaaaact aagaaacaac
    15001 gtcgtcatct tcgtaaagca tctatggtgc attcaggaga ttacaaacgt atcaaagcaa
    15061 tgcttactcg cttgaaataa tagcttgact gtaagtaaac aattctagga aatatttgga
    15121 ggaaataaaa catggcacgt gttaaaggtg gcgttgtatc acgcaaacgt cgtaaacgta
    15181 ttcttaaatt agcaaaaggt tactatggag ctaaacacat cttattccgt actgcaaaag
    15241 aacaagtaat gaactcttac tactatgcat accgtgaccg tcgtcagaaa aaacgtgact
    15301 tccgcaaatt gtggattact cgtatcaatg cggcagctcg tatgaacgga ctttcatact
    15361 cacaattgat gcatggtttg aaattggctg agattgaagt taaccgtaaa atgcttgctg
    15421 acttggctgt taacgatgca gtagctttca cagctcttgc agatgcagct aaagcaaaac
    15481 ttggtaaata acaactgatg agactggaac aggattgtcc agtcttttta aaaataaagg
    15541 agaaagatat ggcttcaaaa atgctacaca cttgcttacg agtagaaaat cttgaaaaat
    15601 caatcgcatt ttatcaagat gcttttggtt ttaaagaatt gcgtcgcaga gattttccag
    15661 accatgcctt cacgattgtc tatctaggtc ttgagggtga tgattatgag ttggagttga
    15721 cttataacta cgatcacggt ccgtatgtgg ttggtgatgg gtttgcccat atcgctctca
    15781 gtacacctga tcttgaggca cttcatcaag aacacagtgc aaaaggctat gaagtgactg
    15841 agccaaatgg tctaccagga actacaccaa actattactt tgtcaaagac cctgatggat
    15901 ataaggtcga agtcattcgt gaaaaataat ttcgtgcaag ttaagtagaa tattcgtttt
    15961 ctacttgact ttttttagct gaaagagtat actaataaaa attcaacctt taaggggagt
    16021 ccagagagac tcacaaggtg tcagataaaa gaatagtgca attttgtaga ggagaccttt
    16081 tgagtgtgct ctcttgtgtt gtacgatttt aactgaggcc ttgcactagc aaggtctttt
    16141 ctttatctgg tccccttaaa atttaaggag gaaaagttat gaatctcaca tgtaagaagc
    16201 gtttgggtgt cattcggttg gaaaccatga aggtggttgc acaagaggaa atcgcgccag
    16261 caatctttga attagtccta gaaggagaaa tggttgaagc catgcgagca ggccaatttc
    16321 ttcatctgcg tgtaccagac gatgcccatc tcttacgtcg tcctatttca atttcgtcta
    16381 ttgacaaggc aaacaagcag tgtcacctca tttatcggat tgagggagct gggactgcaa
    16441 ttttttcaac cttaagtcag ggagacactc ttgatgtgat ggggcctcag ggaaatggtt
    16501 ttgacttgtc tgaccttgat gagcagaatc aggttctcct tgttggtggt gggattggtg
    16561 ttccaccctt gcttgaggtg gccaaggaat tgcatgaacg tggagtgaaa gtagtgacag
    16621 tcctcggttt tgctaataag gatgctgtta ttttgaaaac ggaattggct cagtatggtc
    16681 atgtctttgt aacgacagat gatggttctt atggcatcaa gggaaatgtt tccgttgtta
    16741 tcaatgattt agacagtcag tttgatgctg tttactcgtg tggggctcca ggaatgatga
    16801 agtatatcaa tcaaaccttt gatgatcacc caagagccta tttatctctg gaatctcgta
    16861 tggcttgtgg gatgggagct tgctatgcct gtgttctaaa agtaccagaa aacgagacgg
    16921 tcagccaacg cgtctgtgaa gatggtcctg ttttccgcac aggaacagtt gtattataag
    16981 gagaaaatta tgactacaaa tcgattacaa gtttctctac ctggtttgga tttgaaaaat
    17041 ccgattattc cagcatcagg ctgttttggc tttggacaag agtatgccaa gtactatgat
    17101 ttagaccttt taggttctat tatgatcaag gcgacaaccc ttgaaccacg ttttgggaat
    17161 ccaactccaa gagtggcaga gacgcctgct ggtatgctca atgcaattgg cttgcaaaat
    17221 cctggtttag aggttgtttt ggctgaaaag ctaccttggc tggaaagaga atatccaaat
    17281 cttcctatta ttgccaatgt agctggtttt tcaaaacaag agtatgcagc tgtttctcat
    17341 gggatttcca aggcaactaa tgtaaaagct atcgagctca atatttcttg tcccaatgtt
    17401 gaccactgta atcatggact tttgattggt caagatccag atttggctta tgatgtggtg
    17461 aaagcagctg tggaagcctc agaagtgcca gtttatgtca aattaacccc gagtgtgacc
    17521 gatatcgtta ctgtcgcaaa agctgcagaa gatgcgggag caagtggctt gaccatgatc
    17581 aatactctgg ttggaatgcg ctttgacctc aaaaccagaa aaccaatctt ggccaatgga
    17641 acaggtggaa tgtcaggtcc agcagtcttt ccagtagccc tcaaactcat ccgccaagta
    17701 gcccaaacaa cagacctgcc tatcattgga atggggggag tggattcgac tgaagctgcc
    17761 ctagaaatgt atctggctgg ggcatctgct atcggagttg gaacagctaa ctttaccaat
    17821 ccttatgcct gccctgacat catcgaaaat ttaccaaaag tcatggataa atacggtatt
    17881 agcagtctgg aagaactccg tcaggaagta aaagagtctc tgaggtaaac tgcaatcaat
    17941 ctgttcttga ttttttatta gtttgtaata tgaatttagg agaattttgg tacaataaaa
    18001 taaataagaa cagaggaaga aggttaatga agaaagtaag atttattttt ttagctctgc
    18061 tatttttctt agctagtcca gagggtgcaa tggctagtga tggtacttgg caaggaaaac
    18121 agtatctgaa agaagatggc agtcaagcag cgaatgagtg ggtttttgat actcattatc
    18181 aatcttggtt ctatataaaa gcagatgcta actatgctga aaatgaatgg ctaaagcaag
    18241 gtgacgacta tttttacctc aaatctggtg gctatatggc caaatcagaa tgggtagaag
    18301 acaagggagc cttttattat cttgaccaag atggaaagat gaaaagaaat gcttgggtag
    18361 gaacttccta tgttggtgca acaggtgcca aagtaataga agactgggtc tatgattctc
    18421 aatacgatgc ttggttttat atcaaagcag atggacagca cgcagagaaa gaatggctcc
    18481 aaattaaagg gaaggactat tatttcaaat ccggtggtta tctactgaca agtcagtgga
    18541 ttaatcaagc ttatgtgaat gctagtggtg ccaaagtaca gcaaggttgg ctttttgaca
    18601 aacaatacca atcttggttt tacatcaaag aaaatggaaa ctatgctgat aaagaatgga
    18661 ttttcgagaa tggtcactat tattatctaa aatccggtgg ctacatggca gccaatgaat
    18721 ggatttggga taaggaatct tggttttatc tcaaatttga tgggaaaata gctgaaaaag
    18781 aatgggtcta cgattctcat agtcaagctt ggtactactt caaatccggt ggctacatgg
    18841 cagccaatga atggatttgg gataaggaat cttggtttta cctcaagttt gatggcaaaa
    18901 tggctgaaaa agaatgggtt tacgattctc atagtcaagc ctggtactac ttcaaatccg
    18961 gtggttacat gacagccaat gaatggattt gggataagga atcttggttt tacctcaaat
    19021 ctgatgggaa aatagctgaa aaagaatggg tctacgattc tcatagtcaa gcttggtact
    19081 acttcaaatc cggtggttac atgacagcca atgaatggat ttgggataag gaatcttggt
    19141 tttacctcaa gtctgatggc aaaatggctg aaaaagaatg ggtctacgat tctcatagtc
    19201 aagcctggta ctacttcaaa tctggtggct acatggcgaa aaatgagaca gtagatggtt
    19261 atcagcttgg aagcgatggt aaatggcttg gaggaaaagc tacaaatgaa aatgctgctt
    19321 actatcaagt agtgcctgtt acagccaatg tttatgattc agatggtgaa aagctttcct
    19381 atatatcgca aggtagtgtc gtatggctag ataaggatag aaaaagtgat gacaagcgct
    19441 tggctattac tatttctggt ttgtcaggct atatgaaaac agaagattta caagcgctag
    19501 atgctagtaa ggactttatc ccttattatg agagtgatgg ccaccgtttt tatcactatg
    19561 tggctcagaa tgctagtatc ccagtagctt ctcatctttc tgatatggaa gtaggcaaga
    19621 aatattattc ggcagatggc ctgcattttg atggttttaa gcttgagaat cccttccttt
    19681 tcaaagattt aacagaggct acaaactaca gtgctgaaga attggataag gtatttagtt
    19741 tgctaaacat taacaatagc cttttggaga acaagggcgc tacttttaag gaagccgaag
    19801 aacattacca tatcaatgct ctttatctcc ttgcccatag tgccctagaa agtaactggg
    19861 gaagaagtaa aattgccaaa gataagaata atttctttgg aattacagcc tatgatacga
    19921 ccccttacct ttctgctaag acatttgatg atgtggataa gggaatttta ggtgcaacca
    19981 agtggattaa ggaaaattat atcgataggg gaagaacttt ccttggaaac aaggcttctg
    20041 gtatgaatgt ggaatatgct tcagaccctt attggggcga aaaaattgct agtgtgatga
    20101 tgaaaatcaa tgagaagcta ggtggcaaag attagtacta taagtgaata tgatttgagt
    20161 gaatagtaag ttaaaaatcc tgatttcaag taaaatcagg attttttcat ggatgcaatt
    20221 tttttggagt ctggtgtgac gcggagggtc ttttgtcctg tgtaagtgac aaagccgggt
    20281 tttccaccag ttggtttatt gagttttttg acttcaatca tatctacctg caccagattc
    20341 gacaggcgcc cttgagagaa gtaggcagct aactctgctg cgtctgtctt gactgcatca
    20401 gatgggtcaa gatttcctga gatgacaaca tggcttccag gaatgtcctt agcatggaac
    20461 caaagttcct ccttgcgggc cattttaaag gtcaattcct cattttgaag attgtttcgt
    20521 ccgacataga tgatggtttt gccatcgctt gctagatatt gttctagttt tttgcgtttc
    20581 tggattttct cccgttgtct tctgcggata aaacctgttt gaatcaattc ttcacggatt
    20641 tcagcgattt cttccagtcc agcttggttg aggacggttt ctacactttc cagatagaga
    20701 atagtggctt tggtttcttc aatcaaatca gtcaagtatt tgacagcttc tttgagtttc
    20761 tgataccgtt taaaatagcg ttgggcattc tggttgggag tcagagcctt atcaagcgca
    20821 atcatgatag gttggttggt atagtagttg tctaggataa cctggtcttg gtcgttaggt
    20881 acttggtgga ggaaggttgt cagcaattct cctttttgac gaaattcttc agcgttgtct
    20941 gtctccagta actctttttc ctgttttttg agtttgtgtc ggtttttctg aagttcattt
    21001 tcaacacgac gaatcagttc actggcctgc tgtttgacgc ggtcgcgctc agccttatcc
    21061 ttatagtagg tgtccaacaa atcagaaaga tttgcaaaag gctctcccac ctgatttgca
    21121 aaaggaactg gactgaagga agtctcagtc aagcatggct tggtttcttg attgaaaaaa
    21181 tttcggaaag cggaaaattt ttcactaacc agtatccttt ccaattcatt tgccgtatcg
    21241 cgtcccagac cttgaaagat gctttgaaga ttttttgctg ttagttcttg ggtttgcagg
    21301 atttcaaaga gcttttcatc cttgatagta aaaggattga gagattctgt acttggcgga
    21361 gcgatatagg tcgatcctgg aagtaaggtg cggtagctat tttgtgaaaa accgacgtgt
    21421 ttgataactt cgaggatttt atgactgctt ttatcgacca gtagaatatt actgtgtttt
    21481 cccataattt caataatcaa ggtagcctgg atatggtctc caatctcgtt tttattggaa
    21541 actgtaattt ccacaatacg gtcattttcc acttgctcaa tcgactcaat cagggccccc
    21601 tgcaaatact ttctcaaaac catgataaag gtagaaggtt gggctggatt ttcaaaagtc
    21661 gtttgggtca gctgaatgcg tccaaaaact ggatgggcag aaaggagcag gcgatggctt
    21721 tggcgattgc tgcggatttg caagaccaac tcttgttcaa aaggctgatt gattttctgg
    21781 atgcgaccat tcactaattc gcttcgcaat tcctcaacta tgtggtgtaa aaaaaatccg
    21841 tcaaatgaca tcgttctctc cttgtgattg tattccatag tattatatca aaaaggtaga
    21901 ataaaatcat ggaaatgtgg tataataaag ccaagtaaag agaaacgaga agcacatgta
    21961 tattgaaatg gtagatgaaa ctggtcaagt ttcaaaagaa atgttgcaac aaacccaaga
    22021 aattttggaa tttgcagccc aaaaattagg aaaagaagac aaggagatgg cagtcacttt
    22081 tgtgaccaat gagcgtagtc atgaacttaa tctggagtac cgtgacaccg accgtccgac
    22141 agatgtcatc agccttgagt ataaaccaga attggaaatt gcctttgacg aagaggattt
    22201 gcttgaaaat ccagaattgg cagagatgat gtctgagttt gatgcctata ttggggaatt
    22261 gttcatctct atcgataagg ctcatgagca ggccgaagaa tatggtcaca gctttgagcg
    22321 tgagatgggc ttcttggcag tacacggctt tttacatatt aacggctatg atcactatac
    22381 tccggaagaa gaagcggaga tgttcggttt acaagaagaa attttgacag cctatggact
    22441 cacaagacaa taaacgaaaa tggaaaaatc gtgacctgat atccagttta gaatttgcca
    22501 tcacagggat ttttactgct atcaaggaag aacgcaatat gcgaaaacat gcagtgacgg
    22561 ctctagtggt catccttgca ggttttggtt ttcaggtgtc acgaatcgaa tggctctttc
    22621 tcctattgag cattttcttg gtagtagcct ttgagattat caactctgct attgaaaatg
    22681 tggtggattt ggccagtcac tatcactttt ccatgctggc taaaaatgcc aaggatatgg
    22741 cggctggcgc ggtattagtg gtttctcttt ttgcagcctt aacaggcgca ttgatttttc
    22801 tcccacgaat ctgggattta ttattttaaa cagtaagagg aaattatgac ttttaaatca
    22861 ggctttgtag ccattttagg acgtcccaat gttgggaagt caaccttttt aaatcacgtt
    22921 atggggcaaa agattgccat catgagtgac aaggcgcaga caacgcgcaa taaaatcatg
    22981 ggaatttaca cgactgataa ggagcaaatt gtctttatcg acacaccagg gattcacaaa
    23041 cctaaaacag ctctcggaga tttcatggtt gagtctgcct acagtaccct tcgcgaagtg
    23101 gacactgttc ttttcatggt gcctgctgat gaagcgcgtg gtaaggggga cgatatgatt
    23161 attgagcgtc tcaaggctgc caaggttcct gtgattttgg tggtgaataa aatcgataag
    23221 gttcatccag accagctctt gtctcagatt gatgacttcc gtaatcaaat ggactttaag
    23281 gaaattgttc caatctcagc ccttcaggga aataacgtgt ctcgtctagt ggatattttg
    23341 agtgaaaatc tggatgaagg tttccaatat ttcccgtctg atcaaatcac agaccatcca
    23401 gaacgtttct tggtttcaga aatggttcgc gagaaagtct tgcatctaac tcgtgaagag
    23461 attccgcatt ctgtagcagt agttgttgac tctatgaaac gagacgaaga gacagacaag
    23521 gttcacatcc gtgcaaccat catggtcgag cgcgatagcc aaaaagggat tatcatcggt
    23581 aaaggtggcg ctatgcttaa gaaaatcggt agcatggccc gtcgtgatat cgaactcatg
    23641 ctaggagaca aggtcttcct agaaacctgg gtcaaggtca agaaaaactg gcgcgataaa
    23701 aagctagatt tggctgactt tggctataat gaaagagaat actaagtaga ggtaggctca
    23761 tgcctgcttc ttgtttttac agaaggagga cttatgcctg aattacctga ggttgaaacc
    23821 gtttgtcgtg gcttagaaaa attgattata ggaaagaaga tttcgagtat agaaattcgc
    23881 taccccaaga tgattaagac ggatttggaa gagtttcaaa gggaattgcc tagtcagatt
    23941 atcgagtcaa tgggacgtcg tggaaaatat ttgctttttt atctgacaga caaggtcttg
    24001 atttcccatt tgcggatgga gggcaagtat ttttactatc cagaccaagg acctgaacgc
    24061 aagcatgccc atgttttctt tcattttgaa gatggtggca cgcttgttta tgaggatgtt
    24121 cgcaagtttg gaaccatgga actcttggtg cctgaccttt tagacgccta ctttatttct
    24181 aaaaaattag gtcctgaacc aagcgaacaa gactttgatt tacaggtctt tcaatctgcc
    24241 cttgccaagt ccaaaaagcc tatcaaatcc catctcctag accagacctt ggtagctgga
    24301 cttggcaata tctatgtgga tgaggttctc tggcgagctc aggttcatcc agctagatct
    24361 tcccagactt tgacagcaga agaagcgaca gctattcatg accaaaccat tgctgttttg
    24421 agccaggctg ttgaaaaagg cggttccacc attcggacct ataccaatgc ctttggggaa
    24481 gatggaagca tgcaggattt tcatcaggtc tatgataaga ctggtcaagg atgtgtacgc
    24541 tgtggtacca tcattgagaa aattcaacta ggtggacgtg gaacccactt ttgtccaaac
    24601 tgtcaaagga gggactgatg ggaaaaatca tcggaatcac tgggggaatt gcctctggta
    24661 agtcaactgt gacaaatttt ctaagacagc aaggctttca agtagtggat gccgacgcag
    24721 tcgtccacca actacagaaa cctggtggtc gtctgtttga ggctctagta cagcactttg
    24781 ggcaagaaat cattcttgaa aacggagaac tcaatcgccc tctcctagct agtctcatct
    24841 tttcaaatcc tgatgaacga gaatggtcta agcaaattca aggggagatt atccgtgagg
    24901 aactggctac tttgagagaa cagttggctc agacagaaga gattttcttc atggatattc
    24961 ccctactttt tgagcaggac tacagcgatt ggtttgctga gacttggttg gtctatgtgg
    25021 accgagatgc ccaagtggaa cgcttaatga aaagggacca gttgtccaaa gatgaagctg
    25081 agtctcgtct ggcagcccag tggcctttag aaaaaaagaa agatttggcc agccaggttc
    25141 ttgataataa tggcaatcag aaccagcttc ttaatcaagt gcatatcctt cttgagggag
    25201 gtaggcaaga tgacagagat taactggaag gataatctgc gcattgcctg gtttgataat
    25261 tttctgacag gagccagtat ttctttggtt gtacctttta tgcccatctt cgtggaaaat
    25321 ctaggtgtag ggagtcagca agtcgctttt tatgcaggct tagcaatttc tgtctctgct
    25381 atttccgcgg cgctcttttc tcctatttgg ggtattcttg ctgacaaata cggccgaaaa
    25441 cccatgatga ttcgggcagg tcttgctatg actatcacta tgggaggctt ggcctttgtc
    25501 ccaaatatct attggttaat ctttcttcgt ttactaaacg gtgtatttgc aggttttgtt
    25561 cctaatgcaa cggcactgat agccagtcag gttccaaagg agaaatcagg ctctgcctta
    25621 ggtactttgt ctacaggcgt agttgcaggt actctaactg gtccctttat tggtggcttt
    25681 atcgcagaat tatttggcat tcgtacagtt ttcttactgg ttggtagttt tctattttta
    25741 gctgctattt tgactatttg ctttatcaag gaagattttc aaccagtagc caaggaaaag
    25801 gctattccaa caaaggaatt gtttacttca gttaaatatc cctatctttt gctcaatctc
    25861 tttttaacca gttttgtcat ccaattttca gctcaatcga ttggccctat tttggctctt
    25921 tatgtacgcg acttagggca gacagagaat cttctttttg tctctggttt gattgtgtcc
    25981 agtatgggct tttccagcat gatgagtgca ggagtcatgg gcaagctagg tgacaaggtg
    26041 ggcaatcatc gtctcttggt tgtcgcccag ttttattcag tcatcatcta tctcctctgt
    26101 gccaatgcct ctagccccct tcaactagga ctctatcgtt tcctctttgg attgggaacc
    26161 ggtgccttga ttcccggggt taatgcccta ctcagcaaaa tgactcccaa agccggcatt
    26221 tcgagggtct ttgccttcaa tcaggtattc ttttatctgg gaggtgttgt tggtcccatg
    26281 gcaggttctg cagtagcagg tcaatttggc taccatgctg tcttttatgc gacaagcctt
    26341 tgtgttgcct ttagttgtct ctttaacctg attcaatttc gaacattatt aaaagtaaag
    26401 gaaatctagt gcgagtaaaa attaatctca aatgctcctc ttgtggcagt atcaattacc
    26461 taaccagtaa aaattcaaaa acccatccag acaagattga ggttttaaag tattgtccca
    26521 aggaaagaaa agtaacccta catcttgaat ctaagtagat tttatggtaa aataataggg
    26581 attttaagga gtttgatatg tataacctat tattaaccat tttattagta ttatctgttg
    26641 tgattgtgat tgcaattttc atgcaaccaa ccaaaaacca atccagcaat gtatttgatg
    26701 ccagttcagg tgatttgttt gaacgcagta aagctcgcgg ttttgaagct gtaatgcagc
    26761 gtttgacagg gattttagtc tttttctggc tagccattgc cttagcattg acggtattat
    26821 caagtagata agaaaataat gggcaggact aggtctttgc ctctttttat ttttaaagga
    26881 tgtttgagaa ggttttacag taaaagaaaa ttaaaaaatc tagaaagaaa atatgaaaga
    26941 tagaataaaa gaatatttac aagacaaggg aaaggtgact gttaatgatt tggctcaggc
    27001 tttgggaaaa gacagttcca aggattttcg tgagttgatt aaaaccttgt ccttaatgga
    27061 aagaaagcac cagattcgct ttgaagaaga tggtagtctg acattagaaa ttaagaaaaa
    27121 acatgagatt accctcaagg ggatttttca tgcccataaa aatggctttg gctttgttag
    27181 tctggaaggc gaggaggacg acctttttgt agggaaaaat gatgtcaact atgctattga
    27241 tggtgatacc gtcgaggtag tgattaagaa agtcgctgac cgcaataagg gaacagcagc
    27301 agaagccaaa attattgata tcctagaaca cagtttgaca acagttgtcg ggcaaatcgt
    27361 tctggatcag gaaaagccta agtatgctgg ctatattcgt tcaaaaaatc agaaaatcag
    27421 tcaaccgatt tatgttaaga aaccagccct aaaattagaa ggaacagaag ttctcaaagt
    27481 ctttatcgat aaatacccaa gcaagaaaca tgatttcttt gtcgcgagtg ttctcgatgt
    27541 agtggggcac tcaacggatg tcggaattga tgttcttgag gtcttggaat caatggacat
    27601 tgtatctgag tttccagaag ctgttgtcaa ggaagcagaa agtgtgcctg atgctccgtc
    27661 tcaaaaggat atggaaggtc gtttggatct aagagatgaa attaccttta ccattgacgg
    27721 tgcggatgcc aaggacttgg acgatgcagt gcatatcaag gctctgaaaa atggcaatct
    27781 ggagcttggg gttcacatcg cagatgtttc ctattatgtg accgagggtt ctgcccttga
    27841 caaggaagcc cttaaccgtg cgacttctgt ttacgtgaca gaccgagtgg tgccaatgct
    27901 tccagaacga ctatcaaatg gcatctgctc tctcaatccc caagttgacc gcctgaccca
    27961 gtctgctatt atggagattg ataaacatgg tcgtgtggtc aactatacca ttacacaaac
    28021 agttatcaag accagttttc gtatgaccta tagcgatgtc aatgatatcc tagctggcga
    28081 tgaagaaaag agaaaagaat accataaaat tgtaccaagt atcgaactca tggccaagct
    28141 tcatgaaact ttagaaaaca tgcgtgtgaa acgtggagct ctcaattttg ataccaatga
    28201 agcgaagatt ttagtggata aacaaggtaa gcctgttgat atcgttcttc ggcagcgtgg
    28261 cattgccgag cggatgattg agtcttttat gttgatggct aatgaaacag ttgccgaaca
    28321 tttcagcaag ttggatttgc cttttatcta ccgaattcac gaggagccta aggctgaaaa
    28381 ggttcagaag tttattgatt atgcttcgag ttttggcttg cgcatttatg ggactgccag
    28441 tgagattagc caggaggcac ttcaagacat catgcgtgct gttgagggag aaccttatgc
    28501 agatgtattg tccatgatgc ttcttcgctc tatgcagcag gctcgttatt cggagcacaa
    28561 tcacggccac tatggactag ctgctgacta ttatactcac tttaccagtc caattcgtcg
    28621 ttatccagac cttcttgttc accgtatgat tcgggattac ggctgttcta aggaaatagc
    28681 agagcatttt gaacaagtga ttccagagat tgcgacccag tcttccaacc gtgaacgtcg
    28741 tgccatagaa gctgagcgtg aagtcgaagc catgaaaaag gctgagtata tggaagaata
    28801 cgtgggtgaa gagtatgatg cagttgtatc aagtattgtc aaattcggtc tctttgtcga
    28861 attgccaaac acagttgaag gcttgattca catcactaat ctacctgaat tttatcattt
    28921 caatgagcgt gatttgactc ttcgtggaga aaaatcaggt atcactttcc gagtgggtca
    28981 gcagatccgt atccgtgttg aaagagcgga taaaatgact ggagagattg atttttcatt
    29041 cgtacctagt gagtttgatg tgattgaaaa aggcttgaaa cagtctagtc atagtggcag
    29101 agggcgtggt tcaaatcgtc gttcggataa gaaggaagac aagagaaaat caggacgctc
    29161 aaatgataag cgtaagtatt cacaaaaaga caagaagaaa aaaggaaaga aaccttttta
    29221 caaggaagta gctaagaaag gagccaagca tggcaaaggg cgagggaaag gtcgtcgcac
    29281 acaataaaaa ggcacgccac gactatacaa tcgtagatac gctagaggca gggatggtcc
    29341 tgactggaac tgaaatcaag agtgtacgag ctgctcgaat taatctcaag gatggctttg
    29401 ctcaagtgaa aaatggagaa gtttggctga gcaatgttca tatcgcgcct tacgaagagg
    29461 gcaatatctg gaaccaggaa ccagaacgtc gtcgtaaact cctgctccat aaaaagcaaa
    29521 ttcaaaaatt ggaacaagag accaaaggga caggaatgac cttagttccc cttaaggtct
    29581 atataaaaga tggctacgct aagcttcttt taggacttgc caaagggaag catgactatg
    29641 acaaacggga gtctatcaaa cgtcgtgagc aaaatcgaga tatcgcgcgt gtgatgaaag
    29701 ctgttaatca gcgataaaaa gaggaattga aaatggaaaa attagttgcc tataaacgca
    29761 tgcctttgtg gaataaacaa acaatgcctg aagctgttca gcaaaagcac aatacaaaag
    29821 ttgggacttg ggggaaaatt actgtcttga agggagctct caagtttatt gaattgacag
    29881 aagaagggga agttctagct gaacacctct ttgaagcagg ggcagacaat ccaatggccc
    29941 aacctcaagc ctggcaccga gtggaagctg ccacagatga tgtggaatgg tacttggaat
    30001 tttattgtaa acctgaggat tattttgcta aaaaatacaa taccaatcct gttcattcag
    30061 aggtcctaga ggccatgcag acagtgaaac aagggaaagc tttggatttg ggttgtggtc
    30121 aggggcgtaa ttctcttttt ctagcccagc aagattttga tgtgacggct gtagatcaaa
    30181 atggactagc tcttgaaatc ttgcaaagca ttgtggagca ggaagatttg gacatgcctg
    30241 ttggccttta cgatatcaat tcagctagca ttgaacaaga atatgatttt atcgtttcaa
    30301 cagttgttct catgtttcta caagcggacc gcattccagc tattattcaa aatatgcagg
    30361 agaaaaccag tgttggtggt tacaacctta tcgtttgtgc catggacacg gaggattatc
    30421 cttgctcggt taacttccca ttcaccttta aagaaggaga actggcagac tattacaagg
    30481 attgggaatt ggttaagtac aatgaaaatc caggccattt gcaccgtcgc gatgagaatg
    30541 gcaatcgtat tcaactacgc tttgcgacct tactagctaa gaaaatcaag taaacataca
    30601 tgaagattag gaattttcct gatctttttt cttttttacg aatgatatag aaaaggaggg
    30661 aattcatgtt tgttgcgaga gatgctaggg gagaattggt aaatgtgtta gaggataaac
    30721 ttgagaagca agcatacacc tgcccagctt gtggaggcca gatccatttg cgtcaaggac
    30781 caagtgtacg gacgcatttt gcccataaat ccttaaaaga ctgtgatttt ttctttgaaa
    30841 atgaaagtcc agaacacctg gccaataagg aatccctcta tcactggttg aaaaaagaga
    30901 caaaggttca attagagtac ccgctttcag aacttaaaca gattgcggat gtatttgtaa
    30961 atggcaatct agctctagaa gttcagtgta gtcccttgcc tcagaaagtc cttaaagagc
    31021 gaagtgaggg ctatcgtagt cagggttacc aagtactgtg gttgctgggt caaaaactgt
    31081 ggctcaagga gcgtttgact cgtctacagc aaggttttct ttatttcagt caaaacatgg
    31141 gcttttatgt ttgggaatta gacaaggaaa aacaagtttt aagactcaaa tacctgattt
    31201 accaggatct ccgcggtaaa ctccattatc aaatcaagga attttcctat ggtcaaggta
    31261 gtttattgga aatattgcgt cttccctata agaaacaaaa aatatctcat tttacagttt
    31321 ctgaggacaa ggacatctgt cgctatatcc ggcaacaact ttattatcaa aatctctttt
    31381 ggatgaaaga acaagcagaa gcctatcaaa agggagaaaa tatcctgact tatggactga
    31441 aagaatggta tccacaaatt cgaccaatag tgggcaaatt tttccagatt gaacaagact
    31501 tgactagcta ttatcagcac ttttatacct attaccaaaa aaatcctcaa aatgattggc
    31561 aaaagcttta tccaccagcc ttttatcagc aatatttctt gaaaaatatg gtagaataga
    31621 aaggatggag gaatctaatg gtattacaaa gaaatgaaat aaatgaaaaa gatacatggg
    31681 atctatcaac gatctaccca actgaccagg cttgggaaga agccttaaaa gatttaacag
    31741 aacaattgga gacagtagcc cagtatgaag gccatctctt ggatagtgcg gataacctac
    31801 tagaaatcac tgaattttct cttgaaatgg aacgccagat ggagaagctt tacgtttatg
    31861 ctcatatgaa gaatgaccag gatacacgtg aagctaagta tcaagagtac tatgccaagg
    31921 ccatgacact ctacagccag ttagaccaag ccttttcatt ctatgagcct gaatttatgg
    31981 agattagcga aaagcagtat gctgactttt tagaagctca accaaagctg caggtttatc
    32041 aacactattt tgacaagctc ttgcaaggca aggatcacgt tctttcacaa cgtgaagaag
    32101 aattattggc tggagctgga gaaatctttg gttcagcaag tgaaaccttc gctatcttgg
    32161 acaatgcgga tattgtgttc ccttatgtac tagatgatga tggtaaagaa gttcaactat
    32221 ctcatgggac ttacacacgt ttgatggagt ctaaaaaacg tgaggttcgc cgtggtgcct
    32281 atcaagctct ttatgcgact tacgaacaat tccaacacac ctatgccaaa accttgcaaa
    32341 ccaatgttaa ggtgcaaaat taccgtgcta aagttcgtaa ctacaagagt gctcgtcatg
    32401 cagccctcgc agcgaatttt gttccagaaa gtgtttatga caatttggta gcagcagttc
    32461 gcaagcattt gccactctta catcgctatc ttgagcttcg ttcaaaaatc ttggggattt
    32521 cagatctcaa gatgtacgat gtctacacac cgctttcatc tgttgaatac agttttacct
    32581 accaagaagc cttgaaaaaa gcagaagatg ctttggcagt cttgggtgag gattacttga
    32641 gccgtgtcaa acgtgccttc agcgagcgtt ggattgatgt ttacgaaaat caaggcaagc
    32701 gttcaggtgc ctactctggt ggttcttacg ataccaatgc ctttatgctt ctcaactggc
    32761 aggacaatct ggacaatctc tttactctta ttcatgaaac aggtcacagt atgcattcaa
    32821 gctatactcg tgaaactcag ccttatgttt acggagatta ctctatcttt ttggctgaga
    32881 ttgcctcaac taccaatgaa aatatcttga cggagaaatt attggaagaa gtggaagacg
    32941 acgcaacacg ctttgctatt ctcaataatt tcctagatgg tttccgtgga acagttttcc
    33001 gccaaactca atttgctgag tttgaacacg ccattcacca agcagatcaa aatggggagg
    33061 tcttgacaag cgatttccta aataaactct acgcagactt gaaccaagag tattatggtt
    33121 tgagtaagga agacaatcct gaaatccaat acgagtgggc tcgcattcca cacttctact
    33181 ataactacta tgtatatcaa tattcaactg gctttgcggc cgcctcagcc ttggctgaaa
    33241 aaattgtcca tggtagtcaa gaagaccgtg accgctatat cgactacctc aaggcaggta
    33301 agtcggacta tccacttaat gtcatgagaa aagctggtgt tgatatggag aaggaagact
    33361 acctcaacga tgcctttgca gtctttgaac gccgtttaaa tgagtttgaa gcccttgttg
    33421 aaaaattagg attggcataa aatggttgaa tcgtatagta agaatgctaa ccataacatg
    33481 cgtcgtcctg tcgtcaaaga agaaattgta gacttgatgc gtcagcgtca aaagcaagtc
    33541 acaggtttct tgaaagaatt ggaagacttt gcccgcaagg aaaatattcc tattattccc
    33601 catgaaacgg ttgcttattt ccgttttctt atggaaacca tgcagcctaa aaatattctg
    33661 gaaattggga cggctatcgg tttttcagct ctcttgatgg ctgaacatgc gccaaatgct
    33721 aagattacaa ctattgatcg taatccagaa atgattggtt ttgccaagga aaattttgcc
    33781 cagtttgaca gtcgcaagca aatcactctc ctagagggag atgcggtgga tgtcttatct
    33841 acactgacag agtcttatga tttcgtcttt atggattctg ccaagtctaa atacatcgtc
    33901 tttctgccag aaattctcaa acatttggaa gttggtggtg tggttgtctt ggatgatatt
    33961 ttccaaggcg gtgatgttgc caaggacatt atggaagtcc gtcgaggtca gcgaaccatc
    34021 tatcgaggcc ttcaaagact atttgacgca accttagaca attcagaact caccgcaaca
    34081 ttagtgcctt taggagatgg tattctcatg cttcgtaaaa atgtagcaga tgttcaattg
    34141 cctgacagcg aatgattttc agaaaaattt aagaaaaaat agtaaaatag atagagtaac
    34201 acttatctca aaggagtaga catgaagaaa aaattattgg caggtgccat cacactatta
    34261 tcagtagcaa ctttagcagc ttgttcgaaa gggtcagaag gagcagacct tatcagcatg
    34321 aaaggggatg tcatcacaga acatcaattt tatgagcaag tgaaaaacaa cccttcagcc
    34381 caacaagtct tgttaaatat gaccatccaa aaagtttttg aaaaacaata tggctcagag
    34441 cttgatgata aagaggttga tgatactatt gccgaagaaa aaaaacaata tggcgaaaac
    34501 taccaacgtg tcttgtcaca agcaggtatg actcttgaaa cacgtaaagc tcaaattcgt
    34561 acaagtaaat tagttgagtt ggcagttaag aaggtagcag aagctgaatt gacagatgaa
    34621 gcctataaga aagcctttga tgagtacact ccagatgtaa cggctcaaat catccgtctt
    34681 aataatgaag ataaggccaa agaagttctc gaaaaagcca aggcagaagg tgctgatttt
    34741 gctcaattag ccaaagataa ttcaactgat gaaaaaacaa aagaaaatgg tggagaaatt
    34801 acctttgatt ctgcttcaac agaagtacct gagcaagtca aaaaagccgc tttcgcttta
    34861 gatgtggatg gtgtttctga tgtgattaca gcaactggca cacaagccta cagtagccaa
    34921 tattacattg taaaactcac taagaaaaca gaaaaatcat ctaatattga tgactacaaa
    34981 gaaaaattaa aaactgttat cttgactcaa aaacaaaatg attcaacatt tgttcaaagc
    35041 attatcggaa aagaattgca agcagccaat atcaaggtta aggaccaagc cttccaaaat
    35101 atctttaccc aatatatcgg tggtggagat tcaagctcaa gtagtagtac atcaaacgaa
    35161 tagtccaaat caatgaatca gggaaaaaac tcgacttcag gaaaaaatga agcaaacatt
    35221 cccacaataa aacgcgtagt acaaggtttg tactgacccc caaaagttag acaaataatt
    35281 tatccgaagg atttagttct gtattgcaca gggctaagtc cttttagttt taccttaatt
    35341 ctcttgttgt tgtaataatc aatatagtct ataatggctt gttccaattg attaagtgat
    35401 ttaaatgttt tctcatagcc ataaaacatt tcggatttta aaatgccaaa gaaagattcc
    35461 atcctaccgt tgtcttggct gtttcctttg cgtgacatag atgcttgaat tcccttactc
    35521 tctaggaagc gatgataaga atcgtgttgg tattgccagc cttggtcact atggagaatc
    35581 gtattctcgt agtgcttctc tttgaatgcc tgttccaaca ttaacgatca atcaatttaa
    35641 tcat
//
LOCUS       DAVLGK010000019        35466 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLGK010000019 DAVLGK010000000
VERSION     DAVLGK010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.019"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            176..2158
                     /locus_tag="VXE01_001051"
     CDS             176..2158
                     /locus_tag="VXE01_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0749966.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAANKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2458..7761
                     /locus_tag="VXE01_001052"
     CDS             2458..7761
                     /locus_tag="VXE01_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0749967.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKTPGNSIWYKGNRVAAPETGSINRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPLYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(7928..10087)
                     /locus_tag="VXE01_001053"
     CDS             complement(7928..10087)
                     /locus_tag="VXE01_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV0749968.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10084..10680)
                     /gene="recU"
                     /locus_tag="VXE01_001054"
     CDS             complement(10084..10680)
                     /gene="recU"
                     /locus_tag="VXE01_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV0749969.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10746..11273
                     /locus_tag="VXE01_001055"
     CDS             10746..11273
                     /locus_tag="VXE01_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV0749970.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGTLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            11343..11672
                     /gene="gpsB"
                     /locus_tag="VXE01_001056"
     CDS             11343..11672
                     /gene="gpsB"
                     /locus_tag="VXE01_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV0749971.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11693..12073
                     /gene="rnpB"
                     /locus_tag="VXE01_001057"
     ncRNA           11693..12073
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VXE01_001057"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12158..13315
                     /locus_tag="VXE01_001058"
     CDS             12158..13315
                     /locus_tag="VXE01_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV0749972.1"
                     /translation="MKKEFNLIATAAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13328..14722
                     /gene="mapZ"
                     /locus_tag="VXE01_001059"
     CDS             13328..14722
                     /gene="mapZ"
                     /locus_tag="VXE01_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV0749973.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDANAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14798..16222
                     /gene="gndA"
                     /locus_tag="VXE01_001060"
     CDS             14798..16222
                     /gene="gndA"
                     /locus_tag="VXE01_001060"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV0749974.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLNKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16234..16923
                     /locus_tag="VXE01_001061"
     CDS             16234..16923
                     /locus_tag="VXE01_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0749975.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17021..17986
                     /gene="cbpC"
                     /locus_tag="VXE01_001062"
     CDS             17021..17986
                     /gene="cbpC"
                     /locus_tag="VXE01_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV0749976.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWKYVRGKWYYLDNKNGDMKTGWYQDGSTWYYLDPS
                     NGDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            18005..19003
                     /gene="cbpJ"
                     /locus_tag="VXE01_001063"
     CDS             18005..19003
                     /gene="cbpJ"
                     /locus_tag="VXE01_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEV0749977.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKELEIKTQDSVGRKYGEKRENSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYIGGERRAGWINDASAWYYLDPATGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            19125..20003
                     /gene="mvk"
                     /locus_tag="VXE01_001064"
     CDS             19125..20003
                     /gene="mvk"
                     /locus_tag="VXE01_001064"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV0749978.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSYGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            19985..20938
                     /gene="mvaD"
                     /locus_tag="VXE01_001065"
     CDS             19985..20938
                     /gene="mvaD"
                     /locus_tag="VXE01_001065"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV0749979.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            20925..21932
                     /locus_tag="VXE01_001066"
     CDS             20925..21932
                     /locus_tag="VXE01_001066"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV0749980.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVFLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            21916..22926
                     /locus_tag="VXE01_001067"
     CDS             21916..22926
                     /locus_tag="VXE01_001067"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV0749981.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIVDLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            23003..23701
                     /locus_tag="VXE01_001068"
     CDS             23003..23701
                     /locus_tag="VXE01_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV0749982.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            23698..24693
                     /locus_tag="VXE01_001069"
     CDS             23698..24693
                     /locus_tag="VXE01_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0749983.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            24707..25339
                     /locus_tag="VXE01_001070"
     CDS             24707..25339
                     /locus_tag="VXE01_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0749984.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQADVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            25340..25581
                     /locus_tag="VXE01_001071"
                     /pseudo
     CDS             25340..25581
                     /locus_tag="VXE01_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            25506..25817
                     /locus_tag="VXE01_001072"
     CDS             25506..25817
                     /locus_tag="VXE01_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0749985.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLQLA
                     S"
     gene            25842..26108
                     /locus_tag="VXE01_001073"
                     /pseudo
     CDS             25842..26108
                     /locus_tag="VXE01_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            26258..26497
                     /locus_tag="VXE01_001074"
     CDS             26258..26497
                     /locus_tag="VXE01_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749986.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            26578..27399
                     /gene="cbpG"
                     /locus_tag="VXE01_001075"
     CDS             26578..27399
                     /gene="cbpG"
                     /locus_tag="VXE01_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV0749987.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKNAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSAVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            27418..28440
                     /gene="cbpF"
                     /locus_tag="VXE01_001076"
                     /pseudo
     CDS             27418..28440
                     /gene="cbpF"
                     /locus_tag="VXE01_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(28568..29703)
                     /locus_tag="VXE01_001077"
                     /pseudo
     CDS             complement(28568..29703)
                     /locus_tag="VXE01_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            29912..31681
                     /locus_tag="VXE01_001078"
     CDS             29912..31681
                     /locus_tag="VXE01_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV0749988.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPIANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFFVA
                     ALILHADKSTEDSLEAAQEATQAAKAQSKGQLVSTSVDAVISTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            31705..33660
                     /locus_tag="VXE01_001079"
     CDS             31705..33660
                     /locus_tag="VXE01_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0749989.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            33662..34099
                     /locus_tag="VXE01_001080"
     CDS             33662..34099
                     /locus_tag="VXE01_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0749990.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            34161..35297
                     /locus_tag="VXE01_001081"
     CDS             34161..35297
                     /locus_tag="VXE01_001081"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV0749991.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(35316..>35466)
                     /locus_tag="VXE01_001082"
     CDS             complement(35316..>35466)
                     /locus_tag="VXE01_001082"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0749992.1"
                     /translation="DRTDGVSSKHCFEVVDRTDGVSSKHCFEVVDRTDEVSNICLRQS
                     DANLI"
BASE COUNT        10823 a         6296 c         7954 g        10393 t
ORIGIN      
        1 agaaatagta ttaaaaattc cttgactatg tgatatagtt gagggatttt taaatgatat
       61 tcatattttt tgcaaagatg ttgtttgaaa aataattttc aaaaattctg aaaattctgt
      121 tgacaacttt ctgaaaagag tctataatgg agagaaagtt ttaaaggaga aaaggatgaa
      181 aagttcaaaa ctacttgccc ttgcgggcgt gacattattg gcggcgacta ctttagctgc
      241 atgctctgga tcaggttcaa gcactaaagg tgagaagaca ttctcataca tttatgagac
      301 agaccctgat aacctcaact atttgacaac tgctaaggct gcgacagcaa atattaccag
      361 taacgtggtt gatggtttgc tagaaaatga tcgctacggg aactttgtgc cgtctatggc
      421 tgaggattgg tctgtatcca aggatggatt gacttacact tatactatcc gtaaggatgc
      481 aaaatggtat acttctgaag gtgaagaata cgcggcagtc aaagctcaag actttgtaac
      541 aggactaaaa tatgctgcta ataaaaaatc agatgctctt taccttgttc aagaatcaat
      601 caaagggttg gatgcctatg taaaagggga aatcaaagat ttctcacaag taggaattaa
      661 ggctttggat gatcagacag ttcagtacac tttgaacaaa ccagaaagct tctggaattc
      721 taagacaacc atgggtgtgc ttgcgccagt taatgaagag tttttgaact caaaagggga
      781 tgattttgcc aaagcgacgg atccaagtag tctcttgtat aacggtcctt atttgttgaa
      841 atccattgtg acaaaatcct ctgttgaatt tgcgaaaaat ccgaactact gggataagga
      901 caatgtgcat gttgacaaag ttaaattgtc attctgggat ggtcaagata ccagcaaacc
      961 tgcagaaaac tttaaagatg gtagccttac agcagctcgt ctctatccaa caagtgcaag
     1021 tttcgcagag cttgagaaga gtatgaagga caatattgtc tatactcaac aagactctat
     1081 tacgtatcta gttggtacaa atattgaccg tcagtcctat aaatatacat ctaagaccag
     1141 cgacgaacaa aaggcatcga ctaaaaaggc tctcttaaac aaggatttcc gtcaggctat
     1201 tgcctttggt tttgatcgta cagcctatgc ctctcagttg aatggacaaa ctggagcaag
     1261 caaaatctta cgtaatatct ttgttccacc aacatttgtt caagcagatg gtaaaaactt
     1321 tggcgatatg gtcaaagaga aattggtcac ttatggggat gaatggaagg atgttaatct
     1381 tgcagattct caggatggtc tttacaatcc agaaaaagcc aaggctgaat ttgctaaagc
     1441 taaatcagcc ttacaagcag aaggtgtgac attcccaatt catttggata tgccagttga
     1501 ccaaacagca actacaaaag ttcagcgcgt ccaatctatg aaacaatcct tggaagcaac
     1561 tttaggagct gataatgtca ttattgatat tcaacaacta caaaaagacg aagtaaacaa
     1621 tattacatat tttgctgaaa atgctgctgg cgaagactgg gatttatcag ataatgtcgg
     1681 ttggggtcca gactttgccg atccatcaac ctaccttgat attatcaaac cttctgtagg
     1741 agaaagtact aaaacatatt tagggtttga ctcaggggaa gataatgtag ctgctaaaaa
     1801 agtaggtcta tatgactacg aaaaattggt tactgaggct ggtgatgagg ctacagatgt
     1861 tgctaaacgc tatgataaat acgctgcagc ccaagcttgg ttgacagata gtgctttgat
     1921 tattccaact acatctcgta cagggcgtcc aatcttgtct aagatggtac catttacaat
     1981 accatttgca ttgtcaggaa ataaaggtac aagtgaacca gtcttgtata aatacttgga
     2041 acttcaagac aaggcagtca ctgtagatga ataccaaaaa gctcaggaaa aatggatgaa
     2101 agaaaaagaa gagtctaata aaaaggctca agaagatctc gcaaaacatg tgaaataact
     2161 gttgcaaaat ataagaaagg atttagtatt tctcttgaat gctgaatcct tttttacatt
     2221 tgtaaagaaa gattctaaat gtactgaccc ccaaaagttg gagcctcttt ttgtcagaat
     2281 agagaaaatt tttgttaatt ttacttgttt cctattgctt tctcagttat tatttgttat
     2341 attaaaagta taattatttt tatttatcag ggttaagcat tgcactttca gaggaaggag
     2401 tattttttaa aaaggaaatg taaacgcttg ctaaaaaatg aaaggattta gaagtttatg
     2461 aataaaggat tatttgaaaa acgttgtaaa tatagtattc ggaaattttc attaggtgtt
     2521 gcttctgtta tgattggagc tgcattcttt gggacaagtc cggttcttgc agatagcgtg
     2581 cagtctggtt ccacggcgaa cttaccagct gatttagcta ctgctcttgc aacagcaaaa
     2641 gagaatgatg ggcgtgattt tgaagcgcct aaggtgggag aagaccaagg ttctccagaa
     2701 gttacagatg gacctaagac agaagaagaa ctattagcac ttgaaaaaga aaaaccggct
     2761 gaagaaaaac caaaagagga taaacctgca gctgctaaac ctgaaacacc taagacggta
     2821 actcctgaat ggcaaacggt agagaaaaaa gaacaacagg gaacagtcac tatccgagaa
     2881 gaaaaaggtg tccgctacaa ccaactatcc tcaactgctc aaaatgataa cgcaggcaaa
     2941 ccagccctgt ttgaaaagaa gggcttgacc gttgatgcca atggaaatgc aactgttgat
     3001 ttaaccttca aagaagattc tgaaaagggc aaatcacgct ttggtgtctt cctgaaattt
     3061 aaagatacca ataataatgt ttttgtcggt tatgacaagg atggctggtt ctgggaatac
     3121 aaaactccag gtaatagcat atggtataaa ggcaaccgtg ttgctgctcc tgaaacagga
     3181 tcaataaacc gtctttctat cactctcaag tcagacggtc agctaaatgc cagcaataac
     3241 gatgtcaatc tctttgacac agtgactcta ccagctgcgg tcaatgacca tcttaaaaat
     3301 gagaagaaga ttcttctcaa ggcgggctct tatgacgatg agcgaacagt tgttagcgtt
     3361 aaaacggata accaagaggg ggtaaaaaca gaggataccc ctgctgaaaa agaaacaggt
     3421 cctgaagttg atgatagcaa ggtgacttat gacacgattc agtctaaggt cctcaaagca
     3481 gtgattgacc aagccttccc tcgtgtcaag gaatacagct tgaacggaca tactttgcca
     3541 ggacaggtgc aacagttcaa ccaagtcttt atcaataacc accgaatcac ccctgaagtc
     3601 acttataaga aaatcaatga gacaacagca gagtacttga tgaagcttcg cgatgatgct
     3661 cacttaatca atgcggaaat gacagtacgc ttgcaagttg tggacaatca attgcacttt
     3721 gatgtgacca agattgtcaa ccacaatcaa gtcactccag gtcaaaagat tgatgacgaa
     3781 agaaaactac tttcttctat tagtttcctc ggcaatgctt tagtctctgt ttctagtgat
     3841 caaactggtg ctaagtttga tggggcaacc atgtcaaaca atacgcatgt cagcggagat
     3901 gatcatatcg atgtaaccaa tccaatgaag gatttggcta agggttacat gtatggattt
     3961 gtttctacag ataagcttgc tgctggtgtt tggagtaact ctcaaaacag ctatggtggt
     4021 ggttcgaatg actggactcg tttgacagct tataaagaaa cagtcggaaa tgccaactat
     4081 gtaggaatcc acagctctga atggcaatgg gaaaaagctt ataagggcat tgttttccca
     4141 gaatacacga aggaacttcc aagtgctaag gttgttatca ctgaagatgc caatgcagac
     4201 aagaacgttg attggcaaga tggtgccatt gcttatcgta gcattatgaa caatcctcaa
     4261 ggttgggaaa aagttaagga tatcacagct taccgtatcg cgatgaactt tggttctcaa
     4321 gcacaaaacc cattccttat gaccttggat ggtatcaaga aaatcaatct ccatacagat
     4381 ggtcttgggc aaggtgttct ccttaaagga tatggtagcg aaggccatga ctctggtcac
     4441 ttgaactatg ctgatattgg taagcgtatc ggtggtgtcg aagacttcaa gaccctaatt
     4501 gagaaggcta agaaatatgg agctcatcta ggtatccacg ttaacgcttc agaaacttat
     4561 cctgagtcta aatacttcaa tgaaaaaatt ctccgtaaga atccagatgg aagctatagc
     4621 tatggttgga actggctaga tcaaggtatc aacattgatg ctgcctatga cctagctcat
     4681 ggtcgtttgg cacgttggga agatttgaag aaaaaacttg gtgacggtct cgactttatc
     4741 tatgtggacg tttggggtaa tggtcaatca ggtgataacg gtgcctgggc tacccacgtt
     4801 cttgctaaag aaattaacaa acaaggctgg cgctttgcga tcgagtgggg ccatggtggt
     4861 gagtacgact ctaccttcca tcactgggca gctgacttga cctacggtgg ctacaccaat
     4921 aaaggtatca acagtgccat cacccgcttt atccgtaacc accaaaaaga tgcttgggtt
     4981 ggggactaca gaagttatgg tggtgcagcc aactatccac tgctaggtgg ctacagcatg
     5041 aaagactttg aaggctggca aggaagaagt gactacaatg gctatgtaac taacctcttt
     5101 gcccatgacg tcatgactaa gtacttccaa cacttcactg taagtaaatg ggaaaatggt
     5161 acaccggtga ctatgaccga taacggtagc acctataaat ggactccaga aatgcgagtg
     5221 gaattggtag atgctgacaa taataaagta gttgtaactc gtaagtcaaa tgatgtcaat
     5281 agcccactat accgtgaacg tacagtaacg ctcaacggac gtgtcatcca agatggttca
     5341 gcttacttga ctccttggaa ctgggatgca aatggtaaga aactttctac tgataaggaa
     5401 aagatgtact acttcaatac gcaggccggt gcaacaactt ggacccttcc aagcgattgg
     5461 gcaaagagca aggtttacct ttacaagcta actgaccaag gtaagacaga agagcaagaa
     5521 ctaactgtaa aagatggtaa aattacccta gatcttctag caaatcaacc atacgttctc
     5581 tatcgttcga aacaaaccaa tcctgaaatg tcatggagtg aaggcatgca catctatgac
     5641 caaggattta atagcggtac cttgaaacat tggaccattt caggcgatgc ttctaaggca
     5701 gaaattgtca agtctcaagg ggcaaacgat atgcttcgta ttcaaggaaa caaagaaaaa
     5761 gttagtctca cccagaaatt aactggcttg aaaccaaata ccaagtatgc cgtttatgtt
     5821 ggtgtagata accgtagtaa tgccaaggca agtatcactg tgaatactgg tgaaaaagaa
     5881 gtgactactt ataccaataa gtctctcgcg ctcaactatg ttaaggccta cgcccacaat
     5941 acacgtcgtg acaatgctac agttaacgat acaagttact tccaaaacat gtacgccttc
     6001 tttacaacag gatcggacgt ctcaaatgtt actctgacat tgagtcgtga agctggtgat
     6061 caagcaactt actttgatga aattcgtacc tttgaaaaca attcaagcat gtatggagac
     6121 aagcatgata caggtcaagg cactttcaag caagactttg aaaatgttgc tcagggtatc
     6181 ttcccatttg tagtgggtgg tgtcgaaggt gtcgaagaca accgtactca cttgtctgaa
     6241 aaacacgatc catatacaca acgtggttgg aatggtaaga aagtcgatga tgttatcgaa
     6301 ggaaattggt cactcaagac aaatggacta gtgagccgtc gtaacttggt ttaccaaact
     6361 attccgcaaa acttccgttt tgaagcaggt aagacctacc gtgtaacctt tgaatacgaa
     6421 gcaggatcag acaataccta tgcttttgta gtcggtaagg gagaattcca atcaggtcgt
     6481 cgtggtactc aagcaagcaa cttggaaatg catgaattgc caaatacttg gacagattct
     6541 aagaaagcca agaaggtaac cttccttgtg acaggtgcag aaacagggga tacttgggta
     6601 ggtatctact caactggcaa tgcaagtaat actcgtagtg attctggtgg aaatgccaac
     6661 ttccgtggtt ataacgactt catgatggat aatcttcaaa tcgaagaaat taccctaaca
     6721 ggtaagatgt tgacagaaaa tgctctgaag aactacttgc caacggttgc catgactaac
     6781 tacaccaaag agtctatgga tgctttgaaa gaggcggtct ttaacctcag tcaggccgat
     6841 gatgatatca gtgtggaaga agcgcgtgca gagattgcca agattgaagc cttgaagaat
     6901 gctttggttc agaagaaaac ggctttggta gcagaagact ttgcaagtct tacagctcct
     6961 gctcaggctc aagaaggtct tgcaaatgcc tttgatggaa acttatctag tttatggcat
     7021 acatcatggg gcggaggaga tgtaggcaag cctgcaacca tggtcttgaa agaagcaaca
     7081 gaaatcactg gacttcgtta tgttccacgt ggatcaggtt caaatggtaa cttgcgtgat
     7141 gtgaaacttg ttgtgacaga tgagtctggc aaggagcata cctttactgc aactgattgg
     7201 ccagataaca ataagccaaa agacattgat tttggtaaga caattaaggc taagaaaatt
     7261 gtccttacag gtactaagac ttacggagat ggtggcgata aataccaatc tgcagcggaa
     7321 cttatcttta ctcgtccaca ggtagcagaa acacctcttg acttgtcagg ctatgaagca
     7381 gctttggcta aggctcagaa attaacagac aaagacaatc aagaggaagt agctagcgtt
     7441 caggcaagca tgaaatatgc gacggataac catctcttga cggaaagaat ggtggaatac
     7501 tttgcagatt atctcaacca attaaaagat tctgctacga aaccagatgc tccaactgta
     7561 gagaaacctg agtttaaact tagctcttta gtttccaatc aaggtaagac gccagattat
     7621 aagcaagaaa tagatagacc agaaacacct gaacaaatct tgccagcaac aggtgagagt
     7681 caatctgaca cagccctctt cctagcaagt gttagtctag ccctatctgc tctctttgta
     7741 gtaaaaacga agaaagacta gtatttagta aaacctctta acaagattac ggaagcagtc
     7801 tctatctttt ccaatgaggt ttatagtaca gaaaaagcct gagaagatgt cttctcaggc
     7861 ttttgttaag cacataaata caatagtgct atgacaaaat cacccagaaa aatctgggtg
     7921 ataaatgtta tggttgtgct ggttgaggat tctgattttg ttgatcaggg gttgtatttg
     7981 attgttgcgt attattgtta ggattggtag tcgtactatt atttgtgctt ggagtggttg
     8041 agctagactg tgaagttgaa ctatctgatg atgagcttga actttcagtt gatgggggtt
     8101 gttgtggagc aggtgagttc cacgtagaac gagcaccatt tttaaatacg aattctccat
     8161 ttctgtagag cccctctggt atattccaat cctctggatt gcttccttca gacagatagg
     8221 tcatcataga gcggtaaact ttggcagcga ccgtaaggcc attgcctaca agtggtgtca
     8281 gacggttaga atagcctgtc catacagcca ttgaatattt acgcgtatag ccagcaaata
     8341 gttcatcagg tgctacaaat tgagaggtct tgatgtggtt ttcaatttcc tcgtctgtat
     8401 agttagaggt tcctgtttta ccagcctgag ggagccaagc aagataggca tttcgtccag
     8461 ttccataact caagactgtt ttcatcatgt cggtcatcat ataggctgtc gtttccttca
     8521 tggcacgagt tccgacatta gagaactctt tttcactccc atcactaaag acgactttat
     8581 ggatatacat tggtttatag taagttccac catttgcaaa ggcagcgtaa gcagcagcca
     8641 tcttttcact acttgctcca tattttttgt ctgattcggt tgtgttactt gaaatggcat
     8701 ttgagtagtg aatacttggg tagtcgattc cgagaccatt taggaaagtc ttggcgcggt
     8761 tgagtccgac cttgtttaga gtttccacgg ctgggacgtt tcgcgattgt tgcagggcgt
     8821 attgcaaggt gatgttgcca aagtagcccc tatcccagtt ataaacaggg gtatttgtcc
     8881 cagggtagtt atagggctca tcgtgaacga tagtagcagt tgaatcgtag ataccgtact
     8941 ccaaggcagg agcatagtct gtgatcggtt tcatagttga tccccagtcg cggtttgttt
     9001 ctactgcttg gttaattccg aaggaaacat tacttgactg atggcgtgct cctagctggg
     9061 caatgacttt accgttagaa acatcaacaa tggtagaagc gacttgcaat tcatcgtctg
     9121 gataggcaac gtattcgtct gtattgtaaa tatcccacag atgtttttga gcttcttggt
     9181 ctacatttgt gtagacatcc atcccagttg tgagcaggtt atagcctgtt tcttcttcaa
     9241 cttgattgat gacttccttg aggtaattat ccatgtaagc agggtaatta cttgctgatt
     9301 tgagactttg tagtccatca gtaattggtg tattgactgc tttctcatac tgttcagcag
     9361 agatgtagcc ttgatttttc atttcagata agaccaagtt tcggcggtct tgggctgctt
     9421 ctggatgtga ataggggtca tattggtttg gtgcctgagg cattccagcc agcaaggcta
     9481 actgaggtaa acttaaatta ttgaggtctt taccatagta gttttgagct gctgtctgca
     9541 ttccatagtt cccattagac atgtagacct tatttatata gtaggtcaag atttcttgct
     9601 tggttgcttt ttgttctaac tgaatcgcta accaagcttc ctgagcctta cgagaaatag
     9661 tctggtcgga agtcgaagtt gaaaagtaag tcaacttaat caactgttga gtgagagttg
     9721 atccaccttg gagggaattg ctttgcagat tgcgcaagaa agctcccagg atacggatgg
     9781 tatcaatccc cctgtggtcg aagaagcgat ggtcttcgat agaaacgatt gctttaacca
     9841 aatctgtggg aatatcatta gcttgggcat tgacgcggcg ttcagaaccc aagtcagcaa
     9901 tgagttgatt tttattgtcg tagattttac tagaagttgt tgcaactagt ttactctcgg
     9961 ataggctagg agccttgcta acgtagtaga aaaaaactcc tccgcctaag acaatggctg
    10021 cgataaccaa gcttaagaag ctaatgctca gatacttgat taggcgcaga atcgttggtt
    10081 tgttcatctt gttttaccac ctaataaatg ttctttgata acattgagat aaggaatttg
    10141 agggaaggca ccagccttga tttcatatcc atattctcga atatattcaa gtggcattga
    10201 tttttgtccc ttatcttgat gatagaagcg aatcaaatcg aatgccggca ataagtaggt
    10261 ttcttgctga gaagaaaagt gaagaaggac aaagcagatt ccttgttggg caaggacttg
    10321 ttccatatgc tgaatctgat gtggatgaaa atttttcatc ggaatcgcac gtttttgttt
    10381 tgtttccttg acttcaaagt cgatgtaata tccattataa acgccagaat agtccgtcgt
    10441 tgaagcttgt cgaaaatagg cttcaacaat cttggcacga cttcgttgtg gatagtccac
    10501 ttgtacgatt tgaataggag ttggtttctt atgtataaca gccaagccct gagacaaata
    10561 gtagtcgttg gtagcattga tcatcttttc aaaagacatt cctcgatttg cgaaattttt
    10621 gggttgagaa agagatgttt gtcttttttg tgatgaaact ttatgtggat agttgaccat
    10681 aattctcctt attggtacaa taacatcact ttattatacc ataatttgca cagaaagggt
    10741 taaaaatggc tacagctttg gttttaggct attctgcttt tgatttgggt ttattttctg
    10801 ataaggatcc tcgtcttaaa ttgattaaaa aagcgatacg taaagattta gaggctatgg
    10861 cagcagatgg ggtgtcttgg cttgtgttta cagggacttt gggctttgaa tattgggttt
    10921 tagaggttgc tcaggagatg aaaaccgaat acggtttcca gttggccacc atttttgctt
    10981 ttgaaaccca tggggaaaat tggaatgaag gcaatcagat gaaactgagt cgctttaagc
    11041 aggtagactt tgtcaaatat gcctatcctc gctatgaaca caaggggcag ttaagagatt
    11101 accagcagtt tttgctggaa aacacgacta gttcctatct tttttatgat gaagaaaatg
    11161 aaacaaaact agcttatttt taccaaaaga tgaaaaatca agaggactat tttataaaga
    11221 gattaacatt tgatcaatta aatgaacttg ctgaaaattt ttccgaaaat tgaagctttg
    11281 accttgattt ttgtttgcct ttttttatat aataatacta gcaagcgaga atggagagag
    11341 acatggcaag tattattttt tcagcgaaag atatttttga acaggagttt ggacgtgaag
    11401 tccgtggcta taataaagta gaagttgacg agtttttaga cgatgtcatc aaggactatg
    11461 aaacctatgc tgccttggtc aagtcacttc gtcaggaaat tgcggatttg aaggaagaat
    11521 taactcgtaa accgaaacct tcaccagttc aagcagaacc ccttgaagcg gcaattacaa
    11581 gttctatgac gaattttgat attttgaaac gcctgaatag attggaaaaa gaagtttttg
    11641 gtaaacaaat tttagataac tcagattttt aagtagttat ttgagatgtg caatttttgg
    11701 ataatcgcgt gaggagaatt gcttctcatg aggaaagtcc atgctagcac aggctgtgat
    11761 gcctgtagtg tttgtgctag gcgaaaccat aagcctaggg acgagaaatc gttacggcag
    11821 ttgaaatggc taagtccttg gataggccag agtaggcttg aaagtgccac agtgacgaag
    11881 tctttctgga aacagagaga gtggaacgcg gtaaacccct caagctagca acccaaattt
    11941 tggtcggggc atggagtacg cggaaacgaa cgtagtattc tgactgctat cagctagagc
    12001 tgttagtggt agacagatga ttatcgaagg aagtggtcct agtcacttct ggaacaaaac
    12061 atggcttata gaaaattgca tataggttgg ggctgagaaa ttttctcaac ctcatttttt
    12121 aaagtggaca tatagaaagg tcttgcaaga ctgtaacatg aaaaaagaat ttaatttaat
    12181 tgcaactgcg gcagcagggc ttgaggctgt cgttggtcgt gaagtgcgag agttgggcta
    12241 cgattgtcag attgaaaatg gacgtgttcg ttttcaagga gacgtgagag ctattatcga
    12301 aaccaacctt tggctgcggg cagcagatcg tatcaaaatt atcgtaggaa cgttccctgc
    12361 taagactttt gaagagctat ttcagggagt tttcgcttta gattgggaaa attatttacc
    12421 acttggagct cggttcccga tttcaaaagc taaatgtgtt aagtccaaac ttcacaatga
    12481 gcccagtgtt caggctattt ctaagaaagc tgttgtcaag aaattgcaga aacactatgc
    12541 tcgcccagaa ggggttcctc tgatggagaa tggcccagag tttaagattg aggtctctat
    12601 tctcaaagat gtggcaactg tcatgattga tacgaccggg tctagcctct ttaaacgtgg
    12661 ttatcgtacc gaaaaaggtg gcgctcctat caaggaaaat atggcagcag ccattttaca
    12721 actttctaac tggtatccag acaagccttt gattgatccg acctgtggtt cggggacttt
    12781 ctgtattgag gcagttatga ttgctagaaa gatggcgcca ggtcttcgtc gctcttttgc
    12841 atttgaggaa tggaactgga tcagcgatcg cttgattcaa gaagtgcgca cagaagcggc
    12901 taaaaaagta gaccgtgagc ttgagctgga tatcatgggc tgtgatattg atgctcgcat
    12961 ggtggaaatt gctaaggcca atgctcaggc agctggtgtt gcaggagaca ttacttttaa
    13021 gcagatgcgc gtgcaggatt tacgttccga taaaatcaat ggagtaatca tttccaatcc
    13081 gccttatggt gaacgtttgt cagatgatgc aggggtgacc aagctctatg ctgagatggg
    13141 gcaagtattt gcaccgctga aaacttggag caaatttatc ctgactagtg atgaagcttt
    13201 tgaaagcaag tatggtagcc aagcagataa gaagcgtaag ttatacaacg gaaccttgaa
    13261 agtggatctg tatcaatatt ttggtcagcg tgtcaaacgg caagaggtaa aatagaaagg
    13321 gatactcatg agtaaaaaaa gacgaaatcg tcaaaaaaaa gaaggtcaag aaccgcaatt
    13381 tgattttgat gaagcaaaag agctaacagt tggtcaagct attcgtaaaa atgaagaagt
    13441 ggaagcagga gtcttgcctg aggattccat tttggacaag tatgttaagc aacacagaga
    13501 tgaaattgag gcggataagt ttgcgactcg tcaatacaaa aaagaggagt tcgttgaaac
    13561 tcagagtctg gatgatttaa ttcaagagat gcgtgaggct gtagagaagt cagaagcttc
    13621 ttcggaggaa gttccatctt ctgaagacat cttactaccc ttgcctctgg acgatgagga
    13681 gcaaggcttg gatcctctat tgctagatga tgaaaatcca acagaaatga ctgaagaagt
    13741 ggaagaggag caaaaccttt ctcgtctgga tcaagaggac tcagaaaaga aaagtaaaaa
    13801 aggctttatt ttgaccgttt tggcgcttgt atcagtaatt atttgtgtca gtgcttatta
    13861 tgtctaccgt caagtggctc gttcgaccaa ggaaattgaa acttctcaat caactacagc
    13921 caatcaatcg gatgtggatg attttaatac actttatgac gccttttaca cagatagcaa
    13981 taaaacggct ttgaaaaata gccagtttga taaactgaat caactcaaga ctttacttga
    14041 taagctggaa ggtagtcgtg aacatacgct tgccaaatct aaatatgata gtctagcaac
    14101 gcaaatcaag gctattcaag atgtcaatgc tcaatttgag aaaccagcta ttgtggatgg
    14161 tgtgttggat gccaatgcca aagccaaatc ggatgctaaa tttacggata ttaaaactgg
    14221 aaatacggag cttgataaag tgctagataa ggctatcagt cttggtaaga gccagcaaac
    14281 aagtacttct agctcaagtt caagtcaaac tagcagctca agttcaagtc aagcaagctc
    14341 aaatacgaca agtgagccaa aaccaagtag ttcaaatgag actagaagta gtcgcagtga
    14401 agtcaatatg ggtctctcga gtgcaggggt tgctgttcaa agaagtgcca gtcgtgttgc
    14461 ctataatcag tctgctattg atgatagtaa taactctgcc tgggattttg cggatggtgt
    14521 cttagaacaa attctagcga cttcacgttc acgtggctat atcactggag accaatatat
    14581 ccttgaacgt gtcaatatcg ttaacggcaa tggttattac aacctctaca agccagatgg
    14641 aacctatctc tttaccctta actgtaagac aggctacttt gtcggaaatg gcgctggtca
    14701 tgcggatgac ttggactact aagcagtcgt tacaaaattc tttcttttca aaagtaaaaa
    14761 tgataaaata aaacaaatga aacaagagga gtgtcaaatg acaaaagcta actttggtgt
    14821 cgtaggtatg gccgtaatgg gtcgtaacct tgcccttaat attgaatctc gtggttacac
    14881 agttgctatc tacaaccgta gtaaagaaaa aacggaagat gtgattgctt gccatcctga
    14941 aaagaacttt gtaccaagct atgacgttga aagttttgta aactcaatcg aaaaacctcg
    15001 tcgtatcatg ctgatggttc aagctggacc tggtacagat gctactatcc aagcccttct
    15061 tccacacctt aacaaggggg atatcttgat tgacggagga aatactttct acaaagatac
    15121 catccgtcgt aatgaagaat tggcaaactc aggtatcaac tttatcggta ctggggtttc
    15181 tggtggtgaa aaaggtgccc ttgaaggtcc ttctatcatg cctggtggac aaaaagaggc
    15241 ctacgaattg gtttcggatg ttcttgaaga aatctcagct aaagcaccag aagatggcaa
    15301 accatgtgtg acttatatcg gtcctgatgg agctggtcac tatgtgaaaa tggttcacaa
    15361 cggtatcgag tacggtgata tgcaattgat cgcagaaagt tatgacttga tgcaacactt
    15421 gctaggtctt tctgcagagg atatggctga aatctttact gagtggaaca agggtgaatt
    15481 ggatagctac ttgatcgaaa tcacagctga tatcttgagc cgtaaagacg atgaaggcca
    15541 agatggacca atcgtagact acatccttga tgctgcaggt aacaagggaa ctggtaaatg
    15601 gactagccaa tcatctcttg accttggtgt accattgtca ctgattactg agtcagtgtt
    15661 tgcacgctac atttcaactt acaaagaaga acgtgtatat gctagcaagg tgcttccaaa
    15721 accagctgcc ttcaactttg aaggagacaa ggctgaattg attgaaaaga tccgtcaagc
    15781 cctttacttc tcaaaaatca tttcatacgc acaaggattt gctcaattgc gtgtagcctc
    15841 taaagaaaac aactggaact tgccatttgc agatatcgca tctatctggc gtgatggctg
    15901 tatcatccgt tctcgttttt tgcaaaagat tacagatgct tacaaccgcg atgcagatct
    15961 tgccaacctt cttttggacg agtacttctt ggatgttact gctaagtatc aacaagcagt
    16021 gcgtgatatc gtagctcttg cggttcaagc tggtgtgcca gtgccaactt tctcagcagc
    16081 tattacttac tttgatagct accgttcagc tgaccttcca gctaacttga tccaagcaca
    16141 acgtgactac tttggtgctc acacttacca acgtaaagac aaagaaggaa ccttccacta
    16201 ctcttggtat gacgaaaaat aagtaggtca gccatgggga aacggatttt attacttgag
    16261 aaagaacgaa atctagctca ttttttaagt ttggaactcc agaaagagca gtatcgggtt
    16321 gatctggtag aggaggggca aaaagccctc tccatggctc ttcagacaga ctatgatttg
    16381 atgttattga acgttaatct gggagatatg atggctcagg attttgcaga aaaattgagt
    16441 cgaactaaac ctgcctcagt catcatgatt ttagatcatt gggaagactt gcaagaagag
    16501 ctggaagttg ttcagcgttt tgcagtttca tacatttata agccagtcct tatcgaaaat
    16561 ctggtagcgc gtatttcggc gatcttccga ggtcgggact tcattgatca acactgcagt
    16621 ctgatgaaag ttccaaggac ctaccgcaat cttaggatag atgttgaaca tcacacggtt
    16681 tatcgtggtg aagagatgat tgctctgacc cgccgtgagt atgacctttt ggcgacactt
    16741 atgggaagca agaaagtatt gactcgtgag caattgttgg aaagtgtttg gaagtatgaa
    16801 agtgcgaccg agacaaatat cgtagatgtc tatatccgct atctacggag caagcttgat
    16861 gttaaaggcc aaaaaagcta cattaaaacc gtgcgtggtg ttggatatac catgcaagaa
    16921 tagataagca gttgcagttg tgtaactgct tttttgagga gtttttatat attgacatgc
    16981 agtcgggtct ttgctacaat cgttttagga ggatatatag atgaaacttt tgaaaaaaat
    17041 gatgcaagtt ctactagcag tctttttctt tggtttgcta gctacaaata cggtatttgc
    17101 gaataccaca ggtggccgat ttgttgataa ggataataga aaatattatg taaaagatga
    17161 tcataaagca atctattggc ataaaataga cggtaaaact tactattttg gtgatattgg
    17221 agagatggtt gtcggttggc aatacttaga aattcctgga acaggttatc gtgataattt
    17281 attcgataac caaccagtta atgagattgg ccttcaggag aagtggtact attttggaca
    17341 agatggtgct ttgctagaac aaacagataa acaagtacta gaggcaaaaa cgtctgaaaa
    17401 tacaggaaaa gtatacggtg aacaatatcc tctatctgct gaaaagagaa cttattattt
    17461 tgataataat tatgctgtaa agacaggctg gatttatgaa gacggcaatt ggtattattt
    17521 aaataagcta ggaaattttg gcgatgattc ttacaatcca ctaccaattg gtgaagttgc
    17581 taagggttgg actcaagatt ttcatgttac tattgacatt gatagaagca aacctgctcc
    17641 atggtactac ctagacccag aaactggcat tatgcgaaca ggatggcaat atctaggtaa
    17701 taactggtac tacctccgtt catcaggagc aatggcaaca ggttggaaat atgtacgagg
    17761 caaatggtat tacttagata ataaaaatgg tgatatgaag actggttggt atcaagatgg
    17821 ttcaacttgg tactatttag atccttctaa tggagatatg aaaataggtt ggacaaaagt
    17881 aaatggaaaa tggtattatc tcaattcaaa tggagcaatg gttacaggta gtcaaactat
    17941 cgatggtaaa gtttataact tcgcttcatc tggtgagtgg atttaatgtt ggaggatata
    18001 taaaatgaag cttttgaaaa aaactatgca agctggacta acagtaattt tctttggttt
    18061 gctagctacg aatacagtat ttgcagataa ctctgaagga tggcagtttg tccaagaaaa
    18121 cggtagaacc tattacaaaa agggggacct caaagaaacc tactggcgag tgattgatgg
    18181 taagtactat tattttgatt ctctatctgg agagatggtt gtcggctggc aatatatccc
    18241 gtttccatct aaaggtagta caattggtcc ttacccaaat ggtatcagat tagaaggttt
    18301 tccaaagtca gagtggtact actttgataa aaatggagtg ctacaagagt ttgttggttg
    18361 gaaagaatta gagattaaaa ctcaagacag tgttggaaga aagtatgggg aaaaacgtga
    18421 aaattcagaa gataaagaag agaagcgtta ttacacgaac tattacttta atcaaaatca
    18481 ttctttagag acaggttggc tttatgatca gtctaactgg tattatctag ctaaaacaga
    18541 aattaatgga gaaaactata ttggtggtga aagacgtgca ggttggataa atgatgcttc
    18601 agcttggtac tacctagatc cagcaactgg tattatgcaa acaggttggc aatatctagg
    18661 taataagtgg tactacctcc gttcctcagg agcaatggcc actggctggt atcaggaagg
    18721 taccacttgg tattatttag accacccaaa tggcgatatg aaaacaggtt ggcaaaacct
    18781 tgggaacaaa tggtactatc tccgttcatc aggagctatg gcaactggtt ggtatcaaga
    18841 tggttcaact tggtactacc taaatgcagg taatggagac atgaagacag gttggttcca
    18901 ggtcaatggc aactggtact atgcttatag ctcaggtgct ttggcagtga atacgaccgt
    18961 agatggctat tctgtcaact ataatggcga atgggttcgg taatgaaaga agcgattgtg
    19021 aatggaaaca atcgcttttt ttgtgaaaat ataataaaat agataggaaa gaattaatac
    19081 ttgtatgaaa aataagacgt tttttcgtct agtaaaagga aaaaatgaca aaaaaagttg
    19141 gtgtcggtca ggcacatagt aagataattt taatagggga acatgcggtc gtttacggtt
    19201 atcctgccat ttccctgcct cttttggagg tggaggtgac ctgtaaggta gttcctgcag
    19261 agagtccttg gcgcctttat gaggaggata ccttgtccat ggcggtttat gcctcactgg
    19321 agtatttgga tatcacagaa gcctgcattc gttgtgagat tgactcggct atccctgaga
    19381 aacgggggat gggttcgtca gcggctatca gcatagcggc cattcgtgcg gtatttgact
    19441 actatcaggc tgatctgcct catgatgtac tagaaatctt ggtcaatcga gctgaaatga
    19501 ttgcccatat gaatcctagt ggtttggatg ctaagacctg tctcagtgac caacctattc
    19561 gctttatcaa gaacgtagga tttacagaac ttgagatgga tttatccgcc tatttggtga
    19621 ttgccgatac gggtgtttat ggtcatactc gtgaagctat ccaagtggtt caaaataagg
    19681 gcaaggatgc cctaccgttt ttgcatgcct tgggagaatt aacccagcaa gcagaagttg
    19741 cgatttcaca aaaagatgct gaaggactgg gacaaatcct cagtcaagcg catttacatc
    19801 taaaagaaat tggagtcagt agccctgagg cagacttttt ggttgaaacg actcttagct
    19861 atggtgctct gggtgccaag atgagcggtg gtgggctagg aggttgtatc atagccttgg
    19921 taaccaattt gacacacgca caagaactag cagaaagatt agaagagaaa ggagctgttc
    19981 agacatggat agagagcctg taacagtacg ttcctacgca aatattgcta ttatcaaata
    20041 ttggggaaag aaaaaagaaa aagagatggt gcctgctact agcagtattt ctctaacttt
    20101 ggaaaatatg tatacagaga cgaccttgtc gcctttacca gccaatgtaa cagctgacga
    20161 attttacatc aatggtcagc tacaaaatga ggtcgagcat gccaagatga gtaagattat
    20221 tgaccgttat cgtccagctg gtgagggctt tgtccgtatc gatactcaaa acaatatgcc
    20281 tacggcagcg ggcctgtcct caagttctag tggtttgtcc gccctggtca aggcttgtaa
    20341 tgcttatttc aagcttggat tggatagaag tcagttagcg caggaagcca agtttgcctc
    20401 aggctcttct tctcggagtt tttatggacc actaggagcc tgggataagg atagtggaga
    20461 aatttaccct gtagagacag acttgaaact agctatgatt atgttggtgc tagaggacaa
    20521 gaaaaaacca atctctagcc gtgacgggat gaaactttgt gtggaaacct cgacgacttt
    20581 cgacgactgg gttcgtcagt ctgagaagga ctatcaggat atgctgattt atctcaagga
    20641 aaatgatttt gccaagattg gagaattaac ggagaaaaat gccctggcta tgcatgctac
    20701 gacaaagact gctagtccag ccttttctta tctgacggat gcctcttatg aggctatgga
    20761 ctttgttcgc cagcttcgtg agaaaggaga ggcctgctac tttaccatgg atgctggtcc
    20821 caatgttaag gtcttctgtc aggagaaaga cttggagcat ttatcagaaa ttttcggtca
    20881 tcgttatcgc ttgattgtgt caaaaacaaa ggatttgagt caagatgatt gctgttaaaa
    20941 cttgcggaaa actctattgg gcaggtgaat atgctatttt agagccaggg cagttagctt
    21001 tgataaagga tattcccatc tatatgaggg ctgagattgc tttttctgac agctaccgta
    21061 tctattcaga tatgtttgat ttcgcagtgg acttaaggcc taatcctgac tacagcttga
    21121 ttcaagaaac gattgctttg atgggagact tcctcgctgt tcgcggtcag aatttaagac
    21181 ctttttccct aaaaatctgt ggcaaaatgg aacgagaagg gaaaaagttt ggtctaggtt
    21241 ctagtggcag cgtcgttgtc ttggttgtca aggctttact ggctctgtat gatgtttctg
    21301 ttgatcagga gctcttgttc aagctgacta gcgctgtctt gctcaagcga ggagacaatg
    21361 gttccatggg cgaccttgcc tgtattgtgg cagaggattt ggttctctac cagtcatttg
    21421 atcgccagaa ggcggctgct tggttagaag aagaaaactt ggcgacagtt ctggagcgtg
    21481 attggggatt ttttatctca caagtgaaac caactttaga atgtgatttc ttagtgggat
    21541 ggaccaagga agtggctgta tcgagtcaca tggtccagca aatcaagcaa aatatcaatc
    21601 aaaatttttt aagttcctca aaagaaacgg tggttttttt ggtcgaagcc ttggagcagg
    21661 ggaaagccga aaaagttatc gagcaagtag aagtagccag caagctttta gaaggcttga
    21721 gtacagatat ttacacgcct ttgcttagac agttgaaaga agccagtcaa gatttgcagg
    21781 ccgttgccaa gagtagtggt gctggtggtg gtgactgtgg catcgccctg agttttgatg
    21841 cgcaatcaac caaaacctta aaaaatcgtt gggccgatct ggggattgag ctcttatatc
    21901 aagaaaggat aggacatgac gacaaatcgt aaggacgagc atatcctcta tgcccttgag
    21961 cagaaaagtt cctataatag ctttgatgag gtggagctga ttcattcttc cttgcctctt
    22021 tacaatctgg atgaaatcga tctttcgaca gagtttgctg gtcgaaagtg ggactttcct
    22081 ttttatatca atgccatgac tggtggaagt aataagggaa gagaaatcaa tcaaaagctg
    22141 gctcaggtgg cggaatcctg tggtatttta tttgtaacgg gttcttatag cgcagccctc
    22201 aaaaatccaa cggatgattc tttttctgtc aagtctagtc atcccaatct cctccttgga
    22261 accaatattg gattggacaa acctgtcgag ttaggacttc agactgtaga agagatgaat
    22321 cctgttctat tgcaagtgca tgtcaatgtc atgcaggaat tactcatgcc cgagggagaa
    22381 aggaagttta gaagctggca atcgcatcta gcagattata gcaagcaaat tcccgttcct
    22441 attgtcctca aggaagtggg ctttggaatg gatgccaaga caatcgaaag agcctatgaa
    22501 ttcggtgttc gtacagtgga cctatcgggt cgtggtggca ccagctttgc ctatatcgaa
    22561 aaccgtcgta gtggccagcg tgattacctc aatcaatggg gtcagtctac catgcaggcc
    22621 cttctcaatg cccaagaatg gaaagataag gtcgaactct tggttagtgg aggggttcgg
    22681 aatccgctgg atatgattaa gtgcttggtt tttggtgcta agtctgtggg attgtcacga
    22741 accgttctgg aattggttga aacctacaca gttgaagaag tgattggcat tgtccaaggc
    22801 tggaaagcag acctacgctt gattatgtgt tcccttaact gtgccaccat agtagatcta
    22861 caaaaagtag actatcttct ttatggaaaa ttaaaagaag caaaggatca gatgaaaaag
    22921 gcgtaaccag cgcctttttt ccatcctcag actgaggtga cttttttgaa ttgtgataaa
    22981 atagaaggga gaggatgaac ctatgagaaa atttaaaatc tttttattta tcgaagcctg
    23041 tcttctgaca ggagctctga ttttgatggt atcagagcat ttttcgcgtt ttctgctgat
    23101 actattcctc tttttgcttt tgattcgcta ctacactggt aaagagggaa ataatcttct
    23161 tttagtagcg gcaaccattc tcttcttttt catcgttatg ctcaatcctt ttgtgattct
    23221 agctattttt gttgcggtta tctatagtct ctttcttctt tacccgatga tgaaccagga
    23281 aaaagagcag accaatttgg tttttgaaga ggtcgtgacg gttaagaagg agaaaaatcg
    23341 ttggtttgga aatcttcatc atttttcaag ctaccagact tgccaattcg atgatatcaa
    23401 tctctttcgc ttcatgggca aggacactat tcatctggag agggtcatct taaccaatca
    23461 tgacaatgtc attatcctca gaaagatggt aggaacgacc aaaatcatcg tacctgtaga
    23521 tgtggaagtc agtctcagcg ttaactgtct ctatggggat ttgacttttt tcaaccagcc
    23581 caagcgagcc ctccgcaatg aacactatca tcaagaaaca aaagactatc tcaagagtaa
    23641 caagagtgtc aagattttct tgaccactat gattggtgat gtggaggtgg ttagaggatg
    23701 aaaaaacaag cctatgtcat tattgctctc acctccttcc tatttgtctt ttttttctcc
    23761 cacagcttgc tggaaatact tgattttgac tggtctatct ttttgcacga tgtcgaaaaa
    23821 acagaaaaat ttgtcttttt attgttggtt ttcagcatgt ccatgacctg tctcttagcc
    23881 ctgttttggc gagggatcga agagctttct ctaagaaaaa tgcaggctaa tctcaagcgt
    23941 ttattggcag ggcaagaagt agttcaggtt gtagatccag atttggatgc cagtttcaag
    24001 tccttatcag gtaaacttaa ccttttgaca gaggctcttc aaaaagctga aaatcatagc
    24061 cttgctcagg aagaggaaat catcgagaag gaacggaagc gaattgctcg ggatttgcac
    24121 gatacagtca gtcaggagtt gtttgcggcc cacatgattt tatcgggtat cagtcagcag
    24181 gctttgaaat tggatagaga aaagatgcag atccagttgc agagtgtcac agctatttta
    24241 gaaactgccc agaaggattt gcgggttttg ctcttgcatt tgcgaccagt tgaactggag
    24301 cagaagagct tgatagaagg gattcagatt ctcttaaaag agcttgagga caagagtgat
    24361 cttagggtta gtctcaagca gaatatgacg aaattgccta agaaaatcga ggagcatatc
    24421 ttccgtatcc tgcaagagtt gattagcaat accctccgcc atgcccaggc atcttgccta
    24481 gatgtctacc tctatcagac agatgttgaa ttgcaactga aggtggtgga caatgggatt
    24541 ggtttccagt tagggagctt agacgacttg agttatggac tgcgaaatat caaggagcgg
    24601 gttgaagata tggcagggac ggttcagtta ttaacagctc ccaagcaagg gctggcagtt
    24661 gatatccgta ttcccctgtt agataaggaa tgataaagga gtaaagatga aaattttact
    24721 agtagatgac catgaaatgg tccgattggg cttgaaaagc tactttgacc tccaagccga
    24781 tgtagaagtt gtgggtgagg cgtccaacgg gtctcaaggg attgacttgg ccttggaact
    24841 gcgtccggat gttattgtta tggatattgt catgcctgag atgaatggga ttgatgcgac
    24901 cttggctatc ctcaaagaat ggcctgaagc caagattttg attgtgacct cttatttgga
    24961 caatgaaaaa atcatgccag tcttagatgc tggtgccaaa ggctatatgc tcaagacttc
    25021 tagtgcagat gaattgcttc atgccgtcag taaggtagct gctggcgagc tggccattga
    25081 gcaagaggtt agcaagaagg ttgaatacca ccgcaatcat atggaacttc atgaagaatt
    25141 gactgcgcgt gagcgagatg ttctccaact catcgccaag ggctacgaaa atcagcgcat
    25201 cgcagatgac ctctttatct ctctcaagac ggtcaagacc cacgtgtcca acattcttgc
    25261 caaacttgaa gtcagcgatc gtacccaggc ggctgtctac gcctttcagc accatttggt
    25321 ggggcatgag gagttttaga tgagtttagc agatttactt taggagctag aagcagcaaa
    25381 agactctaaa aagcaaggcc catggaagcc tatatgcgcc atcaattttc ttttctaggt
    25441 attgcggtgc ctgaaagaaa taaactctat aaaaatattt accagaagcg aaaaaaacaa
    25501 agattatcga ttgggatttt gcagacactt gctgggaaaa ggagcctaga aaataccaat
    25561 atgtggctgc taactatttg aaagcaatgc agtcttatct aaaggaaacc gatttgccta
    25621 agctagagca gttagtcgtg acaaaatcct ggtgggacac ggtagatatc ctagatcgag
    25681 tagtagggag tttggtgtat gaacaccctg aactagaaga aataatctta atactcttcg
    25741 aaaatctctt caaaccacgt cagctctatc tgcaacctca aaacagtgtt ttgagcaacc
    25801 tgcagctagc ttcctagttt gctctttgat tttcattgag tataaaatgg agcctatcag
    25861 ataatatctg gctgagacgt gtcgctattg accaccagtt gttaataaaa gagaagacca
    25921 atactcaatt aatggaaaag attctacttc ataacttgaa ccaaacagaa ttttttatca
    25981 ataaagccat tggctggact ctgcgagact actccaaaac gaatcccact tgggtaacat
    26041 gctttattga gaaaaacaag gaaagaatgg ctgaacttag tatcaaagaa gcaagtaagt
    26101 acctctagcg tgattgaaaa gcgcagtcat taattgaaaa gtttacctgt ttatgtgata
    26161 atggagggta tttaaagaag gtggtagatt tcttgattct atagtagatt aagaaattta
    26221 gaatagtacg ctataattac attaggagga tacaataatg aagaaaactg tttataaaaa
    26281 attgggtatt tcaattattg cgagtacttt attggctagc cagttatcga cagtatctgc
    26341 tttgagtgtt atttctagta caggtgaaga atatgaggta agtgagacac tagaaaaagg
    26401 tccagagtct aatgattctt cattatctga gatttcacca acgtatggtt catactacca
    26461 aaagcaatca gaagtattat cggtaatgat gatttgatta aaattgataa tactttacag
    26521 tatccgtatt cgacttcagc tatggtttta tctaagtatt atggagtagc cgatggaatg
    26581 aatgtagaag ggaggggaag tgcgaatttt attaaagata atgtgttaat tacagcggct
    26641 cacaactact acagacatga ctatgggaaa gaagcggatg atatttatgt tcttccggct
    26701 gttagtccaa gtcaagaact atttggaaag atcaaagtaa aggaagttcg ttatttgaag
    26761 gaatttagaa atttaaattc taagaatgca agggaatatg acttggcttt attaattcta
    26821 gaagagccca ttggtgcaaa attagggact ttgggtcttc ctactagtca aaaaaatttg
    26881 acaggaataa ctgtgactat cacaggctat ctatcatata attttaaaat tcatcaaatg
    26941 tatacagata aaaaacaagt tttaagtgat gatggcatgt tcttggatta ccaagttgat
    27001 actttagagg ggtctagtgg atctgcagtt tatgatgcta gtcaccgcgt agtaggagtg
    27061 catactttag gagatggagc taatcaaatt aacagtgcag ttaaattaaa tgaacgaaat
    27121 ttgccattta tttattcggt tcttaaaggt tactctcttg aaggatggaa gaaaataaat
    27181 ggtagttggt actattatag acaacatgat aaacaaacgg gttggcagga gataaatgat
    27241 acttggtatt atttagacag ttccggtaag atgcttacag attggcaaaa agtaaatgga
    27301 aaatggtatt atctcaattc aaatggagca atggttacag gtagccaaac tatcgatggt
    27361 aaagtttata acttcgcttc atctggtgag tggatttaat gttggaggat atataaaatg
    27421 aagcttttga aaaaaatgat gcaagtcgca ctagccacat ttttcttcgg tttgctaggg
    27481 accagtacag tatttgcaga tgattctgaa ggatggcagt ttgtccaaga aaatggtaga
    27541 acctactaca aaaaggggga tctaaaagaa acctactgga gagtgataga tgggaagtac
    27601 tattattttg atcctttatc cggagagatg gttgtcggct ggcaatatat acctgctcca
    27661 cacaaggggg ttacgattgg tccttctcca agaatagaga tttctcttag accagattgg
    27721 ttttattttg gtcaagatgg tgtattacaa gaatttgttg gcaagcaagt tttagaagca
    27781 aaaactgcta cgaataccaa caaacatcat ggggaagaat atgatagccc agcagagaaa
    27841 tgagtctatt attttgaaga tcagcgtagt tatcatactt taaaaactgg ttggatttac
    27901 gaagagggtc attggtatta tttacagaag gatggtggct ttgattcgcg catcaacaga
    27961 ttggcggttg gagagctagc acgtggttgg gttaaggatt cccctcttac ctatgatgaa
    28021 gagaagctaa aagcagctcc atggtactat ctagatccaa caactggcat tatgcaaact
    28081 ggttggcaat ttctaggtaa tagatggtac tacctccatt cgtcaggagc tatggcaact
    28141 ggctggtata aggaaggctc aacttggtac tatctagatg ctgaaaatgg tgatatgaga
    28201 actggctggc aataccttgg taacaagtgg tactatctcc gttcatcagg agctatggca
    28261 actggttggt atcaggaagg ttcgacttgg tactatctaa atgcaagtaa tggagatatg
    28321 aaaacaggct ggttccaagt caatggtaac tggtactatg cctatgattc aggtgcttta
    28381 gctgttaata ccacagtagg tggttactac ttaaactata atggtgaatg ggttaagtaa
    28441 tgaaggctaa ttgtaaactg tgatggatac ttaactttgt ataataggtg gataaaagtc
    28501 ttcacaatca aaaaacgcat agtatcaagg tttttctgta ctgcccccca aaagttagac
    28561 aaataattta tccaaaggat ttagttctgt actgcacagg actaagtcct tttagtttta
    28621 ccttaattct cttgttgttg taataatcaa tatagtctat aatagcttgt tccaattgat
    28681 taagtgattt aaatgttttc tcatagccat aaaacatttc cgatttcaga atcccaaaga
    28741 aggactccac catagtgctt ctctgtgaat gcctgttcca accttgtttg tacttgttct
    28801 aagttgggtg aagttgaaag attataggcg ataatttcac tgttaaagcc atctaaaact
    28861 ggtgataagt aaagcttttg agtacttgct ggaatggcaa attctgtcac atctgtgtag
    28921 cacttttcca ttgttttaga gccttcaaat tggccttgaa tgagattctc tgccttctta
    28981 ccaacgtctc ctttattttc gtttctgtcg cattttagct tgtaaattga gtactttcat
    29041 caagccttga actcttttat gatttaccag ataaccacga tttcttagtt ctaaatgaac
    29101 ccggcgataa gtataatttc ccttgtgttc gataaaaatg gattgaattt cagctttaag
    29161 ctcttggtcc ttatctggtt tgtctagctg tttcaagtga tagtagtagg tccaacgagc
    29221 tagtttaatg gcttttagaa gaagatctaa cgaaaactca gtcattaatt cttgaacaat
    29281 ttctatcttt cttctttctc tttttcctcc ttcaatcgga gttctcttaa cttttttagg
    29341 atagcattct ccgctctcag gtactctctc tcttgttttc tcaacaatag tatacccgtt
    29401 tttcctgtat tgtgctagcc agttaagaag tatcgtacga cttgggaggc agtattcaag
    29461 agaaactcta tctttagtcc agccttcatg tcagacttta tgaatcattt cttgttttaa
    29521 atcaggagaa tagtaacgat ttttcccttt tttgacgaac tctattccgt aacgatcaat
    29581 caatttaatc atatacctaa gattagaatt gtttatccca aatttatttg aaagcttctc
    29641 taagttatat ccttgttttc taagttcata gatctgaact ttatcatcat aagttaattt
    29701 cataataaaa acaccccaaa agttagattt tttctgtcta acttttgggg tgtagttcat
    29761 gtacaccgga tatgatgcgt tttatcattt ttaagccttt ttgcccagcc tcgtcaaaag
    29821 taatgttttg acacaaaatt tgtgacaaaa ctttagtttt aaaggttttt aactttgtat
    29881 atactagttt taagaaaagg aggatgatct aatggaagaa aaagtatcat tgaaagtcag
    29941 ggttcaaaaa ctagggacat cgctttcaaa tatggttatg cccaatattg gagcatttat
    30001 tgcttgggga gtattgactg ccctctttat cgctgatggc tatctgccaa atgaacagtt
    30061 agctactgtt gttggtccta tgttaacgta tttattgcca atcctgattg gttacacagg
    30121 tggatatatg atccatggcc aacgtggtgc cgttgtagga gctattgcta ctgttggtgc
    30181 aatcacaggt tctagtgttc ctatgtttat cggagctatg gtaatgggcc cactgggagg
    30241 atggactatc aagaaatttg atgagaagtt ccaggaaaaa attcgtcccg gatttgaaat
    30301 gttagttaat aacttctcag ctggtctcgt tggttttgca ttattgcttt tggctttcta
    30361 cgcaatcggt ccagtcgtat cgactcttac tggagctgtt gggaatggtg ttgaggctat
    30421 tgtcaatgct cgcctccttc ctatagctaa tattatcatc gaaccggcta aagtcctttt
    30481 cctcaataat gccctcaatc atggcatttt tactcctctg ggagtagaac aggtagctca
    30541 agctggtaag tcaattctct tcctattgga agctaatcct ggaccaggcc tgggaattct
    30601 attagcttat gctgtattcg gtaaaggttc tgctaaatct tcttcttggg gggcaatggt
    30661 tattcatttc ttcggaggga ttcatgaaat ttactttcct tatgttatga tgaagcctac
    30721 tctattttta gctgctatgg caggaggtat ctctggaact tttacttttc aactcttaga
    30781 cgctggtctt aaatctccag cttcaccagg ttctattatt gcgattatgg ctacggcgcc
    30841 aaaaggtgtt tggccccatc taaatgttct tctaggtgtt ttagtggcag cagttgtttc
    30901 tttctttgta gcagccctta ttcttcatgc agacaagtca actgaggatt cgctcgaagc
    30961 tgctcaagag gctacccaag cagctaaagc tcagtctaaa ggtcagttag tatcaacttc
    31021 tgttgatgca gttatttcga cagactcagt ggaaaaaatc attttcgcct gcgatgctgg
    31081 tatgggaagc tctgctatgg gagctagtat tcttcgagat aaggttaaaa aagcaggtct
    31141 agagattcca gtatctaatc aggcaatctc aaatttgctt gatacaccaa aaacattaat
    31201 tgttactcag gaagaactga caccaagagc taaagacaag agtccaagtg ctattcatgt
    31261 ttctgttgat aatttcttag cgtcccctcg ttatgatgaa attgtagctt cattaacagg
    31321 agcttttcca atagcagaaa ttgaaggaga tataccaact tcagcaccag tagatagtca
    31381 ggaaattgac cttaaccata ttgatgctgt agtagttgct tatggtaaag cacagggaac
    31441 tgcaactatg ggctgtgaaa cgattcgggc tatctttaga aacaagaata ttcgtattcc
    31501 agtttctact gccaaaattt cagaattagg tgaatttaat tctaaaaaca taatgattgt
    31561 aacaactatt tctttacagg cagaagtgca gcaagcagca ccgaattctc aatttcttat
    31621 tgtggatagt ttagtaacaa caccagaata tgacaaaatg gctgctagaa tgtacaaata
    31681 gaactagagg tttctaaatt acgaatgcta ttaaccaaac gagaagaaca attattgaag
    31741 gctttcctac atgtagggaa gctttcaatg caagatatga ctgaaatctt acaggtttca
    31801 tctagaacaa tttatcgaac tttatcagat ttgacagata gcatggagca atatggaatc
    31861 gaaataacga agcatgggaa atactatatt ttgactggag agttggatga tttgccgaca
    31921 gaacttgaag tgttagttga gtatagtccc caagaaagac aagagttgat tacctatcgc
    31981 cttctgactg agagtggttt tgtcaccaat gaagcattgc aagagtgcac gaaagtcagt
    32041 aatgtaacta ttattcagga tatttcagat attgataagc gtcttttaga ctttgatctg
    32101 aaaattgaac gacaaaaagg ttatcggatt tctggtgatt cagttggtaa gagaagattt
    32161 ttggctattt tactgacaaa ctgtatctca gtagcagatt tttcaaccgg taattttggg
    32221 agctttgata ttttagaagc agatagaact aggctggcca gtcagattgt taataagcaa
    32281 ctgtcaggtt ttccagatat ggatgctagg atgaagatgt tttttgcgat cttgttatct
    32341 cttataggtc aggagcaaaa cattgaaaat tcacctaata ctagtaagca ggctttggaa
    32401 atttctcaaa aaatttttca agcttactct aagcagactg cacaatttta tagtattcag
    32461 gaaattatct attttgcgag catcttggat gaattaatca ttaaacgtca ggacaatccg
    32521 ctctttacgg agaaatttga tggtgaattt ttctacaata tttcaaatct gattgatacg
    32581 gtttccatgt ataccaagat tgactttttt aaggacaagg ttttattcaa ttttcttttc
    32641 catcatattc ggctcagttt aggcgtccct atcctttttc agggtgaaaa tttgccagaa
    32701 tctgtccaga ttttagttga aaggaataaa tttctttata cagtcatcag tcttttagtg
    32761 aatgatattt ttccgaaata tcttcataca gagtatgagt atggcatgat tgccctacat
    32821 tttatctcta gcttaggccg tagtccagag atttatccag tccgtgtttt gcttttaacg
    32881 gatgaacgtc gggtcactag agatttatta gtcagtaaaa ttaagagtgt tgctcctttt
    32941 gtagagttga tagatattca gtctctagta gattaccaca gtattgatct cagtcagtat
    33001 gattatattt tatctaccaa gccgctgact aatcaggaaa tcgatgtaat ttctagtttt
    33061 ccaaccgtca aagaattgct tgaattacag gaacgacttc agtatgtaca ggcacatcgt
    33121 acaattgtcg cgcgtgatgc tatcgctcca gagaaaagtt atgacttgca agattattta
    33181 atatctagta gtcagctttt gagtcaattc gagttggttc aattggagaa taatcaatca
    33241 tttgagcaca cggtagaaca aatcatccaa tatcagaaga atgtgagtga cagagattac
    33301 ctaacaagaa aattgttatc tcacttccag aatagtccta tggctattcc taatactggt
    33361 ctggtgcttt tacatagtca gtctagcaaa gtaacaacaa atagttttac tatgtttgaa
    33421 ctcaaactac ctatctccgc attgtcaatg aaacgagagg aagaagaggt caaaaggtgt
    33481 ctgctaatgc taatgtctaa agaagctagc gaggaagcga gagatttaat gacagctatt
    33541 agtcagtcga ttattgaaaa tcatctttat acagagattt acaagacggg aaatcaatcc
    33601 attatttatc agatgctaaa tactattttt aacgaaaaaa ttaagaaatt ggagaactaa
    33661 tatgaaactt gaaaaacatt tgattaagct taataaacaa ttttctaaca aggaggaagc
    33721 tatttgttat tgtgggcaag ttctttatga gggtggatat gttaatgaag actatattga
    33781 agccatgatt gagcgagata aagagctatc tgtttacatg ggtaacttta tcgcaatacc
    33841 gcatggaaca gatgcagcaa aaaaggatgt cctcaagtct ggtattacag tcgttcaagt
    33901 ccctagaggg gttgattttg ggaatgtatc taaccctcaa gtggcaacgg ttctttttgg
    33961 tattgctggt attggtaatg aacacttaga aattattcag aaaatttcta tcttctgtgc
    34021 agatgtagat aatgttctta aattagccga tgctcagtca aaagaggaag tattgcgctt
    34081 atttgatgct gttgaataat tgaatttcgt catttgccat ctagtatata tgtccctcaa
    34141 ataggaaaag gagaaattga atgaaacatt ctgttcattt tggtgccggt aatatcggtc
    34201 gtggttttat aggtgaaatt ctatttaaaa atggtttcca tattgatttt gtggatgtca
    34261 ataatcagat aattcatgct ctaaatgaaa agggcaagta tgaaattgaa attgcacaga
    34321 aaggacagtc tcgtatagaa gtaactaatg tggctggaat taatagcaaa gaacatcctg
    34381 agcaagtcat tgaagcgatt caaaagacgg atattattac tactgcaatc ggacctaata
    34441 tactcccttt tatcgctgaa cttctagcca aaggaatcga agctcgccga gttgcaggga
    34501 atacacaggt attggatgtt atggcctgtg aaaatatgat tggcgggtct caatttcttt
    34561 atcaagaagt caagaaatat ttaagtccgg aaggtttgac atttgctgat aactacatag
    34621 gttttccaaa tgctgcagta gacaggattg ttccagcaca aagtcacgaa gattcccttt
    34681 ttgttgtggt cgagcccttt aatgaatggg tcgtggaaac caagcgtctt aaaaatccag
    34741 atttacgtct aaaagatgtg cattatgaag aagatttaga accctttatt gagcgaaaac
    34801 ttttttcagt caattctgga catgcaactt cagcttacat tggtgcgcat tatggtgcca
    34861 agacaatttt ggaagctctt caaaatccta atattaaatc tcggattgaa tctgtattag
    34921 ctgaaattcg gagtctcttg attgccaaat ggaactttga taaaaaagaa ttggagaatt
    34981 atcacaaagt cattatagaa cgatttgaaa accctttcat agtggacgag gttagtcgcg
    35041 tagctcgtac tccaatccga aaattaggct ataatgaacg attcatccgg ccgatacgtg
    35101 aattgaaaga actcagtttg tcatataaaa acctacttaa aacagttggc tatgcctttg
    35161 actatcgcga tgtaaatgat gaagaaagta ttcgattagg tgaattgttg gctaaacaat
    35221 cagtcaaaga tgttgttata caagttacag gtttagacga ccaagaattg attgagcaaa
    35281 ttgtagagta tatttaatat ttttcgaaaa tctcttcaaa tcaggttagc atcgctttgt
    35341 cttaggcata tgttactgac ttcgtcagtt ctatctacaa cctcaaagca gtgctttgag
    35401 ctgactccgt cagttctatc tacaacctca aagcagtgct ttgagctgac tccgtcagtt
    35461 ctatct
//
LOCUS       DAVLGK010000020        35391 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLGK010000020 DAVLGK010000000
VERSION     DAVLGK010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35391
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.020"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            567..2582
                     /locus_tag="VXE01_001083"
     CDS             567..2582
                     /locus_tag="VXE01_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0749993.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLNIGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            2584..3216
                     /locus_tag="VXE01_001084"
     CDS             2584..3216
                     /locus_tag="VXE01_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0749994.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(4161..4574)
                     /gene="ndk"
                     /locus_tag="VXE01_001085"
     CDS             complement(4161..4574)
                     /gene="ndk"
                     /locus_tag="VXE01_001085"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV0749995.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(4685..8362)
                     /gene="rpoC"
                     /locus_tag="VXE01_001086"
     CDS             complement(4685..8362)
                     /gene="rpoC"
                     /locus_tag="VXE01_001086"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV0749996.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMENLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NKETTEVVVDTAVETVEETVE"
     gene            complement(8395..12006)
                     /gene="rpoB"
                     /locus_tag="VXE01_001087"
     CDS             complement(8395..12006)
                     /gene="rpoB"
                     /locus_tag="VXE01_001087"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0749997.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            12422..12492
                     /locus_tag="VXE01_001088"
     tRNA            12422..12492
                     /locus_tag="VXE01_001088"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12454..12456,aa:Cys,seq:gca)
     gene            complement(12690..14021)
                     /locus_tag="VXE01_001089"
     CDS             complement(12690..14021)
                     /locus_tag="VXE01_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV0749998.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(14312..15136)
                     /gene="endA"
                     /locus_tag="VXE01_001090"
     CDS             complement(14312..15136)
                     /gene="endA"
                     /locus_tag="VXE01_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV0749999.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(15175..15363)
                     /locus_tag="VXE01_001091"
     CDS             complement(15175..15363)
                     /locus_tag="VXE01_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0750000.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(15356..16639)
                     /gene="murA"
                     /locus_tag="VXE01_001092"
     CDS             complement(15356..16639)
                     /gene="murA"
                     /locus_tag="VXE01_001092"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0750001.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(16663..16893)
                     /locus_tag="VXE01_001093"
     CDS             complement(16663..16893)
                     /locus_tag="VXE01_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV0750002.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(16951..17988)
                     /locus_tag="VXE01_001094"
     CDS             complement(16951..17988)
                     /locus_tag="VXE01_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV0750003.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(17972..18460)
                     /gene="coaD"
                     /locus_tag="VXE01_001095"
     CDS             complement(17972..18460)
                     /gene="coaD"
                     /locus_tag="VXE01_001095"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV0750004.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDKLVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(18450..18989)
                     /gene="rsmD"
                     /locus_tag="VXE01_001096"
     CDS             complement(18450..18989)
                     /gene="rsmD"
                     /locus_tag="VXE01_001096"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV0750005.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19054..20046)
                     /locus_tag="VXE01_001097"
     CDS             complement(19054..20046)
                     /locus_tag="VXE01_001097"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV0750006.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(20157..20840)
                     /locus_tag="VXE01_001098"
     CDS             complement(20157..20840)
                     /locus_tag="VXE01_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV0750007.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFSELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(20896..21636)
                     /locus_tag="VXE01_001099"
     CDS             complement(20896..21636)
                     /locus_tag="VXE01_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV0750008.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            21670..21948
                     /locus_tag="VXE01_001100"
     CDS             21670..21948
                     /locus_tag="VXE01_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV0750009.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22026..22952
                     /gene="yidC"
                     /locus_tag="VXE01_001101"
     CDS             22026..22952
                     /gene="yidC"
                     /locus_tag="VXE01_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0750010.1"
                     /translation="MKSIKRFALSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(23027..23821)
                     /gene="pflA"
                     /locus_tag="VXE01_001102"
     CDS             complement(23027..23821)
                     /gene="pflA"
                     /locus_tag="VXE01_001102"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV0750011.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(23947..25197)
                     /locus_tag="VXE01_001103"
     CDS             complement(23947..25197)
                     /locus_tag="VXE01_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV0750012.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(25264..26091)
                     /gene="purR"
                     /locus_tag="VXE01_001104"
     CDS             complement(25264..26091)
                     /gene="purR"
                     /locus_tag="VXE01_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV0750013.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYNSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(26358..27299)
                     /locus_tag="VXE01_001105"
     CDS             complement(26358..27299)
                     /locus_tag="VXE01_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV0750014.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(27289..28545)
                     /locus_tag="VXE01_001106"
     CDS             complement(27289..28545)
                     /locus_tag="VXE01_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV0750015.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLYFQENEEEYED"
     gene            complement(28547..29209)
                     /locus_tag="VXE01_001107"
     CDS             complement(28547..29209)
                     /locus_tag="VXE01_001107"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV0750016.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(29172..29828)
                     /locus_tag="VXE01_001108"
     CDS             complement(29172..29828)
                     /locus_tag="VXE01_001108"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0750017.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(29839..30717)
                     /gene="rsgA"
                     /locus_tag="VXE01_001109"
     CDS             complement(29839..30717)
                     /gene="rsgA"
                     /locus_tag="VXE01_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV0750018.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(30719..31591)
                     /gene="rsmA"
                     /locus_tag="VXE01_001110"
     CDS             complement(30719..31591)
                     /gene="rsmA"
                     /locus_tag="VXE01_001110"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV0750019.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQADLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(31722..32030)
                     /locus_tag="VXE01_001111"
     CDS             complement(31722..32030)
                     /locus_tag="VXE01_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750020.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(32023..32664)
                     /locus_tag="VXE01_001112"
     CDS             complement(32023..32664)
                     /locus_tag="VXE01_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750021.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(32666..34696)
                     /locus_tag="VXE01_001113"
     CDS             complement(32666..34696)
                     /locus_tag="VXE01_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0750022.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSIYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTEIGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRDLMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(34773..35069)
                     /locus_tag="VXE01_001114"
     CDS             complement(34773..35069)
                     /locus_tag="VXE01_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0750023.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
BASE COUNT        10103 a         8024 c         6924 g        10340 t
ORIGIN      
        1 tttatgttta gtaacacaat tccttaccaa cagtttattc agaagaatag acaattggag
       61 attcgagtgc aatcacaaaa gaagtccaat ggtcttgatg ttgggaaggc tgattgattt
      121 cgtattactt taaaattcaa ctatttagag aaaggtattc tgatgagagc ttgtaacaat
      181 accagataga tataagaatg gagatgtttg ataaaatgct ttcatagcta accaactgtt
      241 gaaaattatg agttacaaaa tctaaagtat ttaagattgg tttataaaat taggtctctg
      301 cctgtagaaa ggaacgtgca gttagaaagg aggaaaaaat aggatactat aattcagact
      361 gagatttcta attaaaatat gtagttgcat ttcgctcatt ttcataatat ttcattcaga
      421 ggagtaataa tatgttaaaa tttagatttg atgcgggatg gtaaagaata attgaagaag
      481 attcttttat caatagttta gtaagcttgt tagtttatag agggcagggg tatttctgcc
      541 ctctgtttta gaataaggaa tgcactatga aaaaattatt tatactcata tccaacctgc
      601 ttgctagttt gttctttgtt tgggtattta ccatttggac tgatacatat gtctcccatt
      661 attaccccaa cgttgttgta cgtgattctt cccctgaaac aacttttcag catgttgcta
      721 cacgcttgga aaaactagca gaagaaacag atagctttat tgcgattcaa caccaagatc
      781 ctaactcaga aggtactaca gttttttctt atacgacctt tggggacgga aagttgcctg
      841 atgggcttca ggaaaaaaat ctagaagatg ctcaaagtag tagtgttgaa acaaactatt
      901 ttgtattcga tggacaccta gatattcact tgctaaggga agagctaagt caacttggct
      961 tgactaacat gcacctgaca attccatcta aactatctac gttaatggct atctttagta
     1021 acggatttca gttaatcagt ctattgattt tcatcttaac ctttgtagca ctgactttaa
     1081 ttagtcaaat tagccaatta cggtcatcgg gcattcgcct catttcagga gagaaacggt
     1141 ggtccatttt ccttagacca gttggtgagg atttgaaagc gatagctgtt ggtttcagtt
     1201 tagctggcgt gctcgccatt cttatgcaaa aaattctgtc gcttccaacg caatccctaa
     1261 tgaccatagg agcaggcttg ctcagttata atctcatctt gttgtcgatc tccctgtttt
     1321 tcgctcaact cttcgcagtt gggataaaaa agatacacct gatgcagatt ataaaagggc
     1381 aagtgcctgt cagaggaatc attagtttga ttttaatcgg tcaactatta gcgattatta
     1441 ttgtaacact gggaataggg agtagcttaa agtattccca agcctggcaa cagcatcgga
     1501 ttggacaaga ggcttggagt caggaaaggc aactgattac cctatcaatc agccgtgaag
     1561 gaacgagtcc tggttttgat gaacaagctc aaaggaaact cagaacttgg tatcaattga
     1621 tggatctggc tgtttcagaa caaaaggctt tcttatctag acaccagtta attgaccgta
     1681 ctttgcaaaa tggcatggct tcctccaaaa acttgataac ctctacagaa tggcacgatt
     1741 acaacccgaa tggcaatgtc cttatcgtca caccgcaata cttggagcgt caaaacattc
     1801 ctgtagatac aactattgag caaaagatga atcaccttaa tataggggag tttgtcttat
     1861 tgctacctga acacctccgt tcagaggaag aacattataa atctgttttt gaagacgact
     1921 taaccagtcg catgtctagt caagatgaac gacagcaaat gactgctacg gtaggttatt
     1981 tggaatcagg tcaggatcga tttgtgtata atacgacccc tatttcttac cagcagtttt
     2041 tgaaagatcc aatcatcatt gttataacac cccaatcaac tggtccacag tccattttgt
     2101 tttggataga cgcagtacag aactacgttc tctttaatca attgtctgat gcccaggagc
     2161 ttatccagag acaaggcatt gaaaattggg tctcagaaat gcaaacaggt taccacaact
     2221 acatcacatt attggataat atccagaggg aacgttgggt aatgctagca ggagctgtgc
     2281 ttgggattgc aacttcaatc ttgttgttta acactatgaa taggctctac tttgaagaat
     2341 ttagacgtgc catttttatc aaacgcattg caggtctcag gttcttagaa atccatcgca
     2401 cttatctctt tgctcaactg ggtgtgtttt tactgggatt tgttgcgagt gtatttcttc
     2461 aggtagagat aggagttgct ttcttagtct tgttactctt tactggtcta tctcttttac
     2521 agttacatgt ccaaatgcag aaagaaaaca agatgtccat gcttgttttg aagggaggtt
     2581 aatatgattg aacttaaaca ggtgagtaaa tcttttggag aacgagagtt attttcgaat
     2641 ctttcaatga catttgaggc tggaaaagtc tatgccttaa ttggttcaag tggtagcgga
     2701 aaaacaacct tgatgaacat gattgggaaa ttagaacctt atgatgggac gattttttac
     2761 cgaggtaaag acttggccaa ttataaatca agtgattttt tccgtcacga attgggctac
     2821 ctcttccaga actttggctt aattgaaaac caaagtattg aagaaaacct taagctaggt
     2881 ctcattggtc aaaagttgag tcggtcggaa cagcggttga ggcagaagca ggctttagaa
     2941 caggtcggcc tggtttatct tgacctagat aagcgcatct ttgagttatc gggcggagaa
     3001 tcgcaacggg ttgccttggc aaaaattatc ttaaagaatc caccctttat tctggcagat
     3061 gagccaacag cttcaataga cccagcaacc tctcagttga ttatggagat tttgctatct
     3121 cttcgagatg ataataggct aatcattatc gcaacacata atccggcaat ttgggagatg
     3181 gctgatgaag tgttcacgat ggatcatctg aaataaaaat ccttgttttt aattgcacga
     3241 tgagttactg aaatattatc atgaatcaag aattggagtt aatttagaat tgtactttat
     3301 taatattgag gtaacttttt cttgataaag gaagaaataa tggagaggaa gttagaatgg
     3361 agaggaagtt agaatgaaaa aattcgacaa ttatattatt gagaagcctt gcgattctaa
     3421 ttcagataaa ctgcaaaaaa tcttaataat tgaaagtttg gtagatgata ttttgcaatt
     3481 ttctctcaga atcaataata gtgtaggaga gattttcctc ctacaaccgt tttaaaagaa
     3541 aactatcttt attccatgtt attttgagga agatattgtg aaagtcaaag atgatgataa
     3601 agttgagtgg aatttgttag aatttcaaaa atttagagca tttttggctt agtaatctgt
     3661 gttgaaggct caaaacctat ggtaaaaaag tagctttgaa aacgtattgc ctccaaagat
     3721 ttagttaaat aatgatttaa cacaaaaaga aattattgaa gttctggaaa gatgttgttt
     3781 cagtattgag aaaaggtggg aaaaacttgc gattttcaca gagaaaggaa gaaaaagtat
     3841 agaaatatag tcaattgaaa caagaacagg ataaaagaac cttttgtgcc atatttttct
     3901 cctttcgctt tacaattgga ttgaacacct ttattgtatc gcgtttggag tttttttggt
     3961 ataaccttcg acgcacaccc gcatagcggg tgtttttttg tctcgcacct aacggagcga
     4021 gacaaactaa tagtcactta atcaaaaaac gcaccatatc aaaaactaaa aagtttgata
     4081 tcatgcgtca tgtcttaaac taattgacta tactttctat tcaaatgagc ttttaaccaa
     4141 ttgattgagc caatccactc ttaaaaccaa agagcaattt ctcgcttagc tgactcttct
     4201 gaatctgaac catgtacaac attttggata atctcatttt ctccagcagc ttttgcaaaa
     4261 tcacctcgaa tagtgcctgg taaagcttct tctggacgag ttgcacccat catggtccgc
     4321 caagtttcga ttactttggg accagaaatg acacccacaa gaactggacc tgaagtcatg
     4381 aattcacgaa tcggtgggta aaaactctga ccaaccaagt cctgatagtg ctggtcaatc
     4441 aactcttctg aaacctgtga acgaaactcc aatttttcga ttgtaaatcc acgttgttcg
     4501 atgcgcttta acacttcacc cactagtcct ctttttacac catctggttt gatgataaag
     4561 aatgtttgtt ccatactcgt ctcctttgtc agcttctttc ttttatttta ccacatttcg
     4621 tggaaaaatg gagaaagttt tcagaagaga gaatgagaga accctcgggt tctctcattc
     4681 tctcttattc tactgtttct tccacagttt caacggcagt atccacaact acttctgttg
     4741 tttctttatt tccttcttcc tctactggag gattaaggta ttcttcttcg ttgacagcat
     4801 gtggttcaag gttacggtaa cgggccatac cagtaccagc tgggatgatc ttaccgatga
     4861 taacattttc tttaagtcca aggagatggt ctttcttacc acggatagct gcgtcagtaa
     4921 ggacacgagt tgtttcctgg aaggaagccg ctgacaagaa actgtttgtt tcaagtgagg
     4981 ctttggtaat tcccataagg actgggcgac ctgtcgctgg aactccacct gcgataagga
     5041 catctttgtt ggcatctgta aagtcattga tatccatgag ggtacccatg agaagatctg
     5101 tatcacctgg atccatgaca cggactttac ggatcatttg acgaaccatt acctcgatgt
     5161 gtttgtcacc gatttctacc ccttggctac ggtaaacttt ttgtacttca ccgagaaggt
     5221 acgtttcaac tgacaagaca tcacgaactg caaggagacg ttttggttgg atagaacctt
     5281 ctgtcagagc agcaccacgc gctacttggc ccccaacttc gacacgcata cgagctgtaa
     5341 atggaacgac atattcacct tcgccagttt cacccttaac aaagactttc ttggtacgag
     5401 ttgatgcatc ttcttcgata gcagtaactt gtcctttaac ctctgtgata accgcttccc
     5461 ctttaggatt gcgggcttca aagatttctt ggacacgagg aagaccctga gtgatatcgg
     5521 tatttgaggc aaccccacct gtgtggaagg tacgcattgt aagctgtgta ccaggttccc
     5581 cgatagattg ggcagcgatt gtaccaactg cttcaccaac ttcaaccgca tcaccagtcg
     5641 ccaagttgat accgtaacag tgacggcaga caccgtgacg agtgttacat gtaaatacag
     5701 aacggatagt cacttcttcc acaccagcat tgacaatttc acgcgccttg tcttctgtaa
     5761 tcaattcatt tggaccaata atcactgcac cagtttctgg atgtttaaca gttttcttag
     5821 tgtaacgacc gttgagacgc tcttcgagag actcgatcat ctcttttcct tctgcgatag
     5881 aacggatcaa gagaccacgg tcagttccac agtcgtcctc acggatgata acgtcttggg
     5941 caacgtcgac caaacgacga gtcaagtaac ctgagtcggc tgtcttaagg gccgtatcgg
     6001 tcataccttt acgagcaccg tgagttgaga agaacatttc caataccgac aaaccttcgc
     6061 ggaagtttga aaggattggc aattccatga tacgtccatt cggagcagcc atcagaccac
     6121 gcataccggc aagctgtgag aagtttgaga tgttaccacg ggctccagag tccatcatca
     6181 taacgattgg gttcttagga tcttgattag caatcaagcg tttctcaagt ttttcacggg
     6241 cagcacgcca ttcagctgta acagcattgt aacgctcgtc gtctgtgatc ataccacgac
     6301 ggaattgttt ggtgatttgt tcgacacgtt tgtgtgattc ttcaatgatt tcagccttgt
     6361 catcaacgac tgggatatcg gcaataccca ctgtcaatcc tgcaagagtt gagtggtggt
     6421 aaccgaggtt ctccatgcgg tcaagtaggg cagaagtttc tgtcgtacgg aaacgtttga
     6481 agatttcagc gatgatattt ccgaggtttt tcttcttgaa tggagggttg agctcaagat
     6541 tgctgatagc ttccttgata tctccaccaa gtggcaagaa gtatttagct ggaacacctt
     6601 ctgtcaagtt ggcattgttt ggttcttgca agtatggtag cccctctggc atgatatcgt
     6661 tgaagagaat tttaccaact gttgtaagca agaccttatg tctttgctct tctgtccaag
     6721 gcttgttgag gctgtctgtt gcgataccaa cacgtgagtg gaggtgaaca taaccattgc
     6781 ggtaagccat aaccgcttcg tcacggtctt tgaagaccat tccttcacct tcgcgaccag
     6841 cttcttccat ggtcaagtag tagttaccca aaaccatgtc ctgagatgga gtaactaccg
     6901 gtttcccatc tttcgggttc aagatgtgct cagcagctag catgaggata cgagcttctg
     6961 cttgtgcttc ttctgaaagt ggtacgtgga tggccatttg gtccccgtca aagtcagcat
     7021 tgtaggcttc acagacaagt gggtgcaagc gaagagcctt accatcaatc aagactggct
     7081 cgaaggcttg gatacccaaa cggtgaaggg tcggtgcgcg gttcaaaagc actgggtgtt
     7141 ctttaatcac ttcttcaagg atatcccaga tacgctcatc tccgcgttcc accaagcgtt
     7201 tagctgcttt gacgttttgc acgatatcac gggcaacgat ttcacgcatg acaaatggtt
     7261 taaagagttc aatcgccatt tcacgtggca caccacattg gtacatctta agagttggac
     7321 caacggcgat aacggaacgt cctgagaagt caacacgttt accgagcaag ttttgacgga
     7381 agcgtccttg tttaccttta agcatgtggc tcaatgattt caatggacgg ctacctggtc
     7441 ctgtgattgg acgaccacga cgaccattgt caatcaaagc gtcaactgct tcttgaagca
     7501 tacgcttctc attttgaacg atgatacctg gtgcatttaa ctcaagcaaa cgagccaaac
     7561 ggttgttacg gttgataaca cggcggtaaa ggtcattcaa gtcagatgag gcaaaacggc
     7621 caccatccaa ctgcaacatt ggacgaagat ctggtgggat aaccggaagg atgttaagaa
     7681 tcatccattc aggtttgttt ccagacttgt aaaaggcatc caaaacatcc aaacgacgga
     7741 tggctttgac acgtttttgt ccagtagcag ttttcaattc ttctttgagt tcagcaattt
     7801 ctttttcaag atctacttgc ttcaaaaggt cttggatggc ttccgcaccc atcttagcaa
     7861 caaatgaacc ataaccatat tcacgcaagc gctctcggta ttcgcgctct gtcatgatag
     7921 acttgtgctc aagtggtgta tccttaggat caatcaccac ataagccgca aagtagataa
     7981 cttcctcgag ggcacgaggg ctcatatcaa gggtcaagcc catacggctt ggaatcccct
     8041 tgaagtacca gatgtgagat acaggagctt tcaattcgat atgtcccata cgctcacgac
     8101 gaactttcgt acgcgttact tcaaccccac agcggtcaca aacaattcct ctgtaacgaa
     8161 tgcgtttgta cttaccacaa gcacattccc agtcttttgt aggaccaaag atcacttcat
     8221 caaagagtcc ttcacgttct ggtttcaagg tacggtaatt gattgtttca ggttttttga
     8281 cttctccata agaccatgaa cggactttac ttggagaagc tagggtgatt tgcatacttt
     8341 taaaacgatt tacatcaacc actatttctt ccctttctat tctaagtgaa ctgcttattc
     8401 ttgttcagca gcttcttctg ttgcttccgc ttttgttgct ttctcagctt cttcagcttc
     8461 aaaggctgct ttagcctctt gggctgcttt ttcgcgggct ttttcaaggt catctacgtg
     8521 gatgacatct tcgtccattc cttcatccaa gtcgcgaagt tccacttctt ggtcatcttc
     8581 gtctaggaca cgcatgtcaa gaccaagaga ttgcaattct ttgacaagaa ctcggaagga
     8641 ttctggaaca cctggttttg gaattggttt gccttttgta atagcttcat aggctttcaa
     8701 acgtccgttg atatcgtccg acttgtaagt caagatttct tgaaggacat ttgacgcacc
     8761 gtaggcttca agagcccaaa cctccatctc accgaaacgt tgtccaccaa actgagcttt
     8821 acctccgagt ggttgttggg taacagttga gtaaggtccg actgaacgcg catgcaattt
     8881 atcgtcaacc atgtggtgga gtttgatcat gtacatgact ccaacagaaa cacggttatc
     8941 aaatggttca cctgtacgtc catcgtaaag gattgtcttg gcatcgctat ccatacctgc
     9001 ttctttaaca gttgaccaaa gatcttcaga acttgctcca tcaaagactg gtgtcgcaat
     9061 gtgaatacca agagtacgag ctgccatacc aaggtgaagc tccataacct gaccgatatt
     9121 catacgtgat ggcaccccaa gtgggttcaa catgatgtcg actggagttc cgtctggaag
     9181 gtaaggcatg tcttctacag gaacgatacg agagacaacc cctttgtttc cgtgacgtcc
     9241 ggccatttta tctccgacct taatcttacg tttttgagcg atgtaaacac gaaccaacat
     9301 gttaacacct gattgcaact catctccatt tacacgtgta aagatcttaa catcacgaac
     9361 gacaccatcg gcaccgtgtg gtacacgaag agaagtatca cgcacttcac gagacttgtc
     9421 tccaaagata gcgtgcaaga gacgttcttc agctgaaaga tctttctcac ccttaggtgt
     9481 tactttacct acaagaatat caccttcttt aacctcagca ccaatacgga taatccccat
     9541 ttcgtcaagg tctttgaggg catcttcacc aacgtttgga atttcgcgag tgatttcttc
     9601 aggcccaagc tttgtatcgc gcgtttctga ttcgtattct tcaaggtgaa cagatgtgta
     9661 gacatcgtcc ttcaccaagc gttcgctcat gataacggca tcctcgaagt tgtaaccttc
     9721 ccaagtcatg taggcaacga ttgggttttg tccaagcgcc atttctccat tttccataga
     9781 aggtccgtca gcgatgaaat cgcctttttc aacgacatca ccaactttta cgagagtgcg
     9841 ttggttgtaa gcagtacctg agtttgaacg acggaatttt tggatgtggt aaacatccaa
     9901 tgaaccatct tcacgacgaa cttctacctt gtcagcatct gcgtaagtaa ctttaccatc
     9961 atactgagca atcacagccg caccagaatc gtgggctgct tggtattcca taccagtacc
    10021 aacgtaaggt gcctgaggat taatcaatgg cacagcctga cgttgcatat tggctcccat
    10081 gagggcacgg ttggagtcat cgttttccaa gaaaggaata catgctgtcg caacggcaac
    10141 tacctgtttt ggtgaaacgt ccatgtagtc aacaatatta gctggatact cttggttgac
    10201 cccttggtga cgtcccatga caatcttctc agcaaaggtt ccatcttcat tcagacgaga
    10261 gttagcctga gctacagtat attcatcttc ttcatcagct gtcaaccaaa caatttcgtt
    10321 cgtgacaaca cctgtttcac ggtcaacctt acggtatggt gtttgaacaa aaccatattt
    10381 gttcaagtgt ccgtaagatg acaagttatt gatcaaaccg atgttaggtc cttcaggtgt
    10441 ctcgattgga cacatacgac catagtgagt gtagtgcacg tcacgtactt catatccggc
    10501 acggtcacga gtcaaaccac caggtcctaa ggctgacaaa cggcgtttgt gagacaactc
    10561 agaaagcggg ttgtgttggt ccatgaactg tgacaactgt gatgaaccaa agaattcttt
    10621 aactgcagct gttacaggac ggatattgat aatttgttgt ggtgtcaaga cttcattgtc
    10681 ctgaacagac atacgttcac ggacattacg ttccatacga gaaagtccca aacgtacttg
    10741 gttggcaagc aattcaccaa ccgcacggat acgacgattt ccaaggtggt cgatatcatc
    10801 tacacggcca agtccttcag ccaagttgag gaagtagctc atctcagcaa ggatatctgc
    10861 aggagtcacc gtacgaacct tgtcatctgg gttagcatta ccaatgatcg ttacgacgcg
    10921 atctggatca gttggagcaa taaccttgaa tttttgaaga acaacaggct cagtcacaac
    10981 ggctgcatcg tttgggatgt agacaatctt gttcaagtcg ccatccaaat ggctttcaat
    11041 gctttcaatc acgctacgag tcataatcgt accagcttct accaagattt ctccagtttc
    11101 agggtctacc aatggctctg caatggtttg gttgagcaaa cgtgttttaa cattgagttt
    11161 tttattgatt ttgtaacgac caactgctgc caagtcatag cgacgtgggt caaagaagcg
    11221 agccacaagc aagctacgtg agctttcagc cgtcttaggc tcacctggac gaaggcgttc
    11281 gtaaatttct ttcaaggctt cgtctgtacg agagtccatt ggattcttgt ggatatcttt
    11341 ttcaacagtg ttgcgaacca attcgctgtc accaaaaata tcaaagattt catcatcacc
    11401 tgagaaacca agagcacgaa ccaaggttgt aaatggaatc ttacgagtac ggtcgatacg
    11461 agtgtaggtg atatcttttg agtcgctttc aagttccaac caagctccac ggttagggat
    11521 aacagttgaa ccatagccca ccttaccatt tttgtctact ttgtcgttaa agtaaacacc
    11581 tggtgagcgg accaactgag aaacgataat acgttcacca ccattgatga tgaaagtacc
    11641 catttctgtc atgattggga aatcaccaaa gaaaacttct tgggtcttga tttcgcctgt
    11701 ttctttattg atcaagcgga aggttacaaa aattggtgct gagtagctag catcgtgaat
    11761 acgagcttct tctagcgtgt attttggttc cttgatttca tatccaacaa attccaactc
    11821 cattgtgtct gtgaagtttg aaattggcaa tacatcttca aacacttcct taagaccgtg
    11881 gtctaggaaa gctttgaatg agtcagtttg aatttcaatc aaatttggta agtcaagaac
    11941 ttctttgatt cttgaaaaac tacgacgggt acgatgtttc ccgtattgaa cgtcatgtcc
    12001 tgccaagatg attctccttt gtaaataagt tccaagcctt gtcaatcagg cttttctaat
    12061 cgtcatatgg ttgtaaaccc cttatcaccg tgtcctcttg acgaattttc agaatcttta
    12121 agcctctgtt acaaatgctc ataatcttga aaaaaagcac aaaaagagca gctaaatctg
    12181 actttttcag aagatttaac tgctgtgagc cttgtctgga caatatttca gacaaaacct
    12241 acgacaaatg attacccata ttatacccta tttagctaga tttttcaagg ggtttcagta
    12301 ggtttttggt aaattttttc ccatagaaaa cttggcatca cattcgaatc acgctatggt
    12361 acaaaaaact gaaaaaacta ttgactgaaa atcattttca aggtataata ataaacgtta
    12421 aggcggtata gccaagtggt aaggcacggc tctgcaaaag cttgatcgtc ggttcaaatc
    12481 cgtctaccgc cttctataac ttgatttatc aggtttcaaa tgaacagaaa gcccaatttg
    12541 aagggctttt tttattttcc ctcgaataaa tacgtataac tttaaaaact tttggagcga
    12601 gtttgtggca gagttctttc catggcataa ttcccttttg aaatcaattg aaaaaagctt
    12661 cgtcacgcct ggtgacaaaa gcctctagtt tattctgttt cttcttctat ttcgacttct
    12721 gtgatttgga cttttacctt ggtaacacgt ccattcttca ctttatcatt ggttaagata
    12781 aactgtttgt tttggctgac caattcatag ctgagtttct cagtcgttgg aatggttccc
    12841 actcctgtca aataataacc agcgatggta tcaacgtcat cactttccag ctcaacatca
    12901 aagtaattat tgaaatcatt gagggtcata gttccttgaa caatgtaggt atcctcgcca
    12961 atctgatgaa catctattgc tgctttgtcc gtttcatcat caatttcacc aacaatttcc
    13021 tctaagaggt cttccaaagt caccaaacca gccataccac cgtattcatc cagcaagatt
    13081 gccatttgtc tttgggtatt tcgcagttct tttagcaagt catccacaaa aatagtttca
    13141 ggtacaaaaa gtggatcttg taaaattctc ttccaaacaa tattgtcaaa accgtccaca
    13201 aagcctgcct taaggagact cttggtgtga atgattccaa ttacattgtc cttatcccca
    13261 tcataaactg ggatacgaga ataattttgt tttaaaatac tttggataat ggcttgacta
    13321 tcatcctgaa tatccaccat aaaggcatcc gttcgaggaa ccataacctc tcgtgccatc
    13381 agttcatcga gcgaaaagac accttgtagc atctcaatct catcagcatc caatgtttct
    13441 tcactatttg tcagcatata ggcaatttca tcacgggtca tcttttcatc cgcatcatcg
    13501 aatgacatag gagtcaaatg gctcaagaaa ttggtcgaag cagctaaaag ccaaacaaaa
    13561 ggactgacta gttttccgat cccaatgata atcggcgctg tacgaattgc caaggcatcc
    13621 tttagattaa gagcgattct cttaggatat aattccccaa aaacgatgga aatataggtc
    13681 aaaaatgcca aggatagaaa agttgccacg gcttgtgctg tttcgccatt cccaagccaa
    13741 gaggcaatca cacgtcctag agtatcagtt aaactcgccc ctgataagat tgtaatcagg
    13801 gtgattccta cctgaatggt tgataaaaag tggttaggat tttctagtac cttcagcagg
    13861 cggatgtagc gtctgtctcc ttcttccgcc ttttgttcaa ctcgggcacg attaagagaa
    13921 accatggcca tttctgtggc tgagaaaaag gcatttaata ccgtcaagat aaacaataaa
    13981 acaaattgta gcaacaaatt ctgactactt gggtcttcca tagttcttct cctaaaatag
    14041 tatcttatcc tttattatat cacaaaattt aatccaatac atattatttt tttcttagcg
    14101 taacttccat ctctctccca aaactggaag ttacgctaag acggatttcc actgatttca
    14161 cgcgtttttc tcatactaaa agctaggttg tgggaaactg gaagttagtt ttagaagtta
    14221 ctattttttc ttagtaccta ttctagccct gcttaaacta gtaaaaagaa ctcctacatc
    14281 cataagtgac ataggagttt aggcttatct tttactgagt tacagttact tctccagttc
    14341 ggtaatccag ttgaagtccc ttttgaacat tgggaactag aacattgaat tccaattctc
    14401 catccgaaga cttggcttca atctgtgaag ctgagggaac taaatcctcg tttgaagcgt
    14461 agtaaagggt tacacggtaa cggacacgct tgttttggtc caaggcttta cgcaccttgc
    14521 tttcatagta gttttgacca gtcgaatact cggcttgtgc ctgatttgcc caggctgtct
    14581 gaacagcaat gtttttagga ttgcttgttg aggcatcaaa accatccaaa ccaccgatta
    14641 aggcatagcc taacaaatga cctctatcga ctgcatgggt ataagagccc tttagattct
    14701 tgacctgatg ccaacctgga ggagtccaag aagttgaacc attcccagtt tctttacgat
    14761 tcttgtactg acgagtggcc ttagacaaga gggcattagc tacggttgga acagtttcct
    14821 tgcccactgt ctttgtttta ttgtcagcgt agggcttact tgaaaccttg gcatctagat
    14881 ttgttttatt accattgacg ataaaagcac ctgagccatt ccactccaga ctccccttta
    14941 tttgactctt gactgcgtct gttaagacac tctctgccaa tgcttgacta ggagcttcag
    15001 acgcttgttt tttctgacta agcttggttt taggactatt agctgtcgac tgcatctgct
    15061 tgatataata gctccctgta gacaaaagca ataacactag cagtccgatt agtgtctgtc
    15121 ttgttttttt gttcatattt ctccttatct ttagaaaaag gctggttctc cagcctaatt
    15181 tcctgtaaat ttatgaatca attcctgcca ttttgctgga gacaggatag cccatggatc
    15241 ttgacccttg cccaagattc cataacctac cattaaaccg attcctagag ccagagtacc
    15301 taaaatcagt actatgatga ctaaaagtaa acgcttgact acgtagcttg atttcttatt
    15361 catcttcatc acttgcctca atccgctgaa tcttagcacc tagctgcgcc aacttctcat
    15421 ggaaaccgta gtaacctcta tccaagtgaa ccaatttacc gaccacagtt tctccctgtg
    15481 ctaccaaacc tgtcaaaatc aaggctgcac tggcacgaag gtcagttgaa agaacttctg
    15541 ctccctgcaa aggctgtcca ccaacaatac gagctgtatc acggataatc tcagaatgca
    15601 agcccatgcg gcgcatctct tctaggtgtt ggaaacgatt ttcgaaaact gtctccacca
    15661 tggttgattc gccttttgca actgtcatca aggctgtaaa ttgagcctgc atatctgttg
    15721 gaaatcctgg gtggggcaag gttttcacat gaacagcttt tagattttct agttgagaac
    15781 gaacacgaat tccttcgtct tcttcaatta cttcaacacc catttcaagt aacttggcaa
    15841 tcaagggacg gttgtgctcc cagacagcgt ctcgaatcaa gacatcacca ccagtcatgg
    15901 cagcagctac cataaaggtt cctgcttcga tacggtcttg gactacattg tgagtcgtac
    15961 catgaagttt ctcaacacca gtaatggtta tagtctctgt accagcacct ttgaccttgg
    16021 ctcccatttc attaaggaga atggctaagt caacaatctc aggctcacgc gcagcattct
    16081 caatcactgt caccccatca gccagagtcg ctgccatcat caagttctgc gttgcaccaa
    16141 cacttggaaa gtccatatag atatgagcgc catgcaagcg ttctgccttg gcttcgatgt
    16201 aaccagctgt ctgactaatc ttaaccccca tagcttccag acctttcaaa tgaagatcaa
    16261 taggacggct accaatcgta caaccacctg gcatggatac cttggcatga cccacacggg
    16321 caaggattgg ccctaataca acgatggagg cacgcatctt gctgacatac ttgtaagggg
    16381 cttcctcagt gatgtcgcca gtagcatcca ccttgacaag atgagcttcc tcatcaaagt
    16441 caaccttggc attcaaacca ccaactacct gattcataat aaagacatcc gacaaaatcg
    16501 gaacattctg caagacggtc tttccttcac ttgctagaat agtcgctgcc aacaagggta
    16561 agactgcatt ttttgctccc tcgatcgtca cgcttcctac cagacgatta tcgccacctt
    16621 gaaccacaat tttatccata ctcgtttcct ttactcttga tttcataata atcctctaag
    16681 cgcttcttgc cacaaatgat acaggctaat aaagaaagaa ctcaggatgt agcctatgac
    16741 aatgctaaaa aaggctacta ataaacgaac ttttcttgta ttatcatctg tcacttttaa
    16801 aaccttctcc catctaacaa gatcctttaa aaggtaaaaa ctcacataaa taaagaacat
    16861 atgactactt agagtgaata ataattgaac catttgacta ttataccatc ttctctgttt
    16921 gtgcgctagt ttggaaactt cactcaaaaa ttagggattg tttttcaagt aatcaatcgc
    16981 atcttgtagg gttttaacgg gcacgatttt catatccgtc ttgattgttt tagccgcttc
    17041 tagggctgtt tggtagttgt ttttcgcgtc cggatgcgcc ttttgttctt cttcgctaac
    17101 agggttatca ggagcaaaga aaatagcagc acctgcccta gccgaagcta caaccttctt
    17161 atcaatacct ccaatgtctc ccacattacc atcgcggtca atggtacctg taccggcaac
    17221 aatacgacca ttacgaagat ctgggtgagc tatttgagta tagatagcta gactaaacat
    17281 gagaccagca cttggaccgc caataccagc tgttgaaaag ctaattggga cattgctgat
    17341 tacctctgta cggtcaatca agccgattcc aattccattt ttgccatttt ccaaggtgat
    17401 gatttttcct tctgcagact tggtttgccc atcctcttca taggtgacct tgacggaatc
    17461 ccctaatttt tgagaactga cgtaatcaat caagtctttg gaactatcaa aggtctgatc
    17521 attgactgct gtgactgtat cagagatatt gagaatccct ttaaaggttg aattatccgt
    17581 cacattcaaa acataaactc caaagtactt gagttcgata tccttaccag ctgtttttag
    17641 tccttgatac ttggccatat tttgcgatgt ttgcatgtag aattgattga ttcgcataaa
    17701 ttcaacatcg gaagaaccac ctgtagtctc ctgagcacta cgaatatctg taaaaggtgt
    17761 caaccaagca taaatcatat gagctaaagt ggcatgttga acaccaaccg taacgaattg
    17821 ataggcacca gcttccttat cttctgtgtc atttacttta aggacttggc gaatatcttc
    17881 cgaaccacct ggaacctcta tataataagg caagggcact acaaatgcca agaaagtcac
    17941 aatcaaggcc gcaatgacgt ataagggcca tctaatcttt tttttcattt cttatttcct
    18001 ccaaaatact ctcgggaaca tagcaggcaa tatcctgacc aaacttcaaa agctctctaa
    18061 cgcctgatga actgatatag agatgttcag gccggctatg taaataaata gtctctatat
    18121 cagaagacag ctgatgattg tagtaatcaa aactagcttc atattgcaaa tccgccgcat
    18181 tcctcaaccc ccgtactagg aaagtagccc ccagtctttt tgcaacatcg accaccaatt
    18241 tatcatgaga agccacgact tcaacatttt ccaaatgtcc caaagccttt tctagccccc
    18301 gtttacgatt ttcaagaggg agaaatcctt gtttgtgggg attaaaaaaa atacccacat
    18361 aaagcttatc aaagagtctg ctcgcccgtt caatgatatc cagatgccca tttgtcatcg
    18421 gatcaaatga gcctgtgaat aagccaatct tatctgacat agactgtcac cttactaatt
    18481 ccataaatct tttccttcca gatacccaga caggcaatct cttctggaag ttcaacggcc
    18541 ttatccgtct cgcacacaac cataacatct tcagaaaaaa gctctctctc agccattttt
    18601 tcaatatctg ctacgatttg ttccttggca tagggagggt ctaagaaaac gaggtcaaat
    18661 tccccagata cctgttccaa tgccctctct gcatccatct tgaggagttg aaattttcca
    18721 acttccttgg tcatctggat attttcagcc acgatggtct gagccttacg gtctcgctcc
    18781 accaaaacag cactggacat gccacgcgat actgcttcga tagataaacc accactacct
    18841 gcataaaggt ccaagactcg tcccccttca aagtagggac caatcatgtt aaaaatggct
    18901 cccctaacct tatccgaagt aggtcttgtc gtcttgcctt ctagtgtctt gaggggacgt
    18961 cccccataga ttcctgatac gattttcata ctgtttatta taccaaatta tagacaaaaa
    19021 gagaaagaaa accgaacctt gcggttcgat tctctacaaa atattttcgt aagtatcgcg
    19081 gacttcttga ggccaaacac ttgtttgcac ttctccgatg tgtctcttgc gaagtaggaa
    19141 catggccata cgagattgtc caattcctcc accgattgtc aatgggaata gaccattcaa
    19201 caaagacttg tgccattcca attccaagcg gtcttcatca cctgtaattt ccacctgacg
    19261 tctaagagtt tcttcatcta cacgaattcc catagaagac aactcaaagg ctccacctaa
    19321 agactcattc cagacaagaa tatcaccatt tagacccttg tagccattct cagactcgct
    19381 tgtccagtca tcatagtctg gtgcacgtcc atcgtgcggt ttaccatctg gcaactcgcc
    19441 accgatacca atcaaaaaga cggctccaaa ttctttacaa atcgcatttt cacgttcttt
    19501 cggtgtcaag tctgggtagc gttctaccaa ttcttctgta tggataaagg tgatttgttt
    19561 tggcaagata gactcgatgt catagcgggc ttcaacagct agctcagtca ggcgaatagc
    19621 cttataaatc ttctcaactg tttcttttag ataaacgatg ttacgcttac catttgggat
    19681 aaccttctcc cagtcccact ggtcaacata aacagagtgg gttgcatcca aggaatcctc
    19741 atctggacga agggctttca tgtggacaaa gagaccctct ccttcaccaa agccaaaacg
    19801 agccaaggtg tggcgtttcc atttagcaag tgagtgcacc acttcataag tagcatcagg
    19861 gatttggaga accttgacag atactggatt ttccacacca gacaggttgt cctgcattcc
    19921 gtcaccgacc ttactcaaga taggaccttg aacttcgaca acttctagct tatctttcaa
    19981 atactgggta aaagtgtttt tgacaaagga aatttcttct tgttgatgga taaaactttt
    20041 cttcatagac aactcctcaa aaatttaata aacgtattat acacctattt ccaaaaaaag
    20101 aaaagagaaa atttaaaaaa atcagtgtca ctcaaaacac tgatttcata gaccttttag
    20161 tcattgcgac cgaagatacg tagaatactt aggaaaagat tgataaaatc aagatagatg
    20221 ctgagagcca ttgacaccac ccagcctgtc gctacacgac cttgtgattg ttcataggcg
    20281 aggcgaatct tttgattatc ccaagcaatc aaccctgaaa aaaccaaaac catggctacg
    20341 ctaatcatat aatcaaagaa gccactagcc aagaaaatat tgactaccat agcaatcagt
    20401 aaaccaatga gagctgccat cattgctcga ccaatcccac tcaagtcttt cttggtaaag
    20461 ataccaactg ccgccatgac aaagaagaga agggcgctcg atacaaaggc agataaaact
    20521 gtacccggag tatagaaagc caccacaaaa ctaagggtaa agccgtttaa aacggagtaa
    20581 agtaaaaata ctggaagagc agctggacta tttcttgaag ccatgctact ggcaacgaaa
    20641 accaaagcca actccgaaaa agtagcaatg gtcaaccaga gacgcccctg catcaacaag
    20701 taaaccaact gagactgaaa gaccgtcaac ataaggcctg ataccaaagc agatagtccg
    20761 attcccagac caacaaaggc ataaacctta gcgtaaaatt gattgagacc tgcacggtca
    20821 tgtataatag tgtgattcat ccttttctcc ttttctgtga acatctttcc ttgattataa
    20881 caaaaaaagt taaaattagc ttaaatggaa gattaaaata ccggctgcaa ctgcaacatt
    20941 caaactctcg gcctgcccct tcatgctaat atggaccaac tggtctgcac tttcagccat
    21001 aaggggacta attccttgac cctcatttcc cataactagt acaaaatttt ctatagaagg
    21061 cagttctctg taatcaacag aatctttaga tagggttgtt gctagcactg ggatagctac
    21121 ctttttagtt tcgtcaagaa gcgcttgact agtcatccgg taaatgggca gatggaaatg
    21181 actaccttgc atggaacgta gggttttgag actgtagatg tctgccgact tatctgaaac
    21241 aatcactcct gtaaaacctg ctgcatccgc agttcgaatg atagttccta cattaccagg
    21301 atcttgcaca tcttccaaaa acaagaactt gccctgactc aaatcagctt gtcctacttc
    21361 ttctttttga accacggcaa caattccctg tggagtctga gaatccgcca aatctagcaa
    21421 aatatcctct gacacccaga cagtttgcga aaaagtagct aactgatctc gataattttc
    21481 tagggtaaag attttctcaa tcgtcactcc agcttgaaca gcttcttcaa acaagtgcca
    21541 gccttcaatt aaataggcag acttgcggta ttttttttgg tgtaatttct tggcattttt
    21601 taccacagaa ttggcttttg aggttataat agtcatagaa atattataac acaatcaaag
    21661 gggtttggta tgcaaaaggt tagaatgatt gcccaaggta gggtacaggg agtcggcttt
    21721 cgttggggtg tttacagctt ggcacttgaa attggtggca tcacaggtcg agtatggaat
    21781 aacgacgatg gcacagtgga aatcttagcc caagcagact catctgctat catggcaaaa
    21841 tttatccaag aaatccgaaa aggaccgaca cctttttcaa aagtaagcta cttagatgtc
    21901 aaactaagca actttcctcc ctactctgat tttaaaatcg caaattaggt ctccagaact
    21961 attgtatatt ttgtaaaaaa acagtagaat agaaaggtat aatttttaaa gaaggaataa
    22021 aaacagtgaa atctattaaa cgttttgcac tctcagctat gggagtggct atgttgcttg
    22081 tcttgactgg ctgtgtcaat gtcgataaaa ccacaggtca gccaacagga tttatttgga
    22141 atacgatcgg agcgcctatg gctgaagcca tcaagtactt cgctactgat aaaggtctag
    22201 gctttggtgt cgctatcatt atcgtaacca ttatcgtacg cttgattatc ttaccacttg
    22261 gtatctacca atcatggaag gcaacgcttc actctgaaaa gatgaacgcc ctcaagcacg
    22321 tccttgagcc acaccaaacg cgtctcaaag aagcgactac tcaagaagaa aaactcgaag
    22381 cccaacaagc tctctttgct gctcaaaaag agcacggtat cagcatgttt ggcggtgtag
    22441 gatgtttccc tatcctcctt caaatgcctt tcttctctgc tatctacttt gctgcccaac
    22501 atactgaagg ggttgctcaa gcaagctacc taggcattcc tctaggttct ccaagtatga
    22561 ttttggttgc ctgtgctggt gtcctttact atcttcaatc gctcctttca cttcacggag
    22621 tagaagatga aatgcaaaga gaacaaatca agaaaatgat ttacatgagc ccactcatga
    22681 tcgtcgtctt ctccctcttc tcaccagcta gtgtcacact ttactgggtt gtcggtggtt
    22741 tcatgatgat tctccaacag tttatcgtca actatatcgt tcgtccaaaa cttcgcaaaa
    22801 aagtccgtga agaactagcc aagaacccac caaaagcaag tgctttctct aaaccaagtg
    22861 gacgaaaaga cgttacccct gaacaaccaa ctgctatcac aagcaagaaa aaacacaaaa
    22921 atcgcaacgc tggaaaacaa cgttcgagat aagaagaaaa aggcttagct gatttgctaa
    22981 gtctttttgc aaatcaaaag cccgatgttt ccatcaggct tcttttctat ccatgtacac
    23041 gtttcatata atcttgataa ctttcggtat ccatgagttt tttagcgttc ttgacgcgat
    23101 ctgctgttgg tggtttgact ccttcgaggg aatatggaat tccaagttca cgccacttga
    23161 actcacccat ggtgtgataa ggtagaattt caaacttatc aacatttttg agggtcttga
    23221 cgaacttacc aagttcaatc aagtcatcat ctctgtctgt caatcctgga actagcacgt
    23281 ggcgaatcca gacaggtttt ccaatatctg atagatactg ggcacaagcc aagatatttt
    23341 tattagtttg gctagtgaca atcttgtgct gttcttcgtt gatttccttg atatccaaaa
    23401 gaaccaagtc agtgacagcc atgagtttgt caaacttctc aaggtaacgt ggtttattac
    23461 ggaaaggaag agcacaggta tccaaggtac agtggattcc ttgttcctta gccttggtga
    23521 agagagcaat caggaaatca atctgcaaga gagcttctcc tccactgact gtaatcccac
    23581 ccttatttcc ccagaaacca cggtagcgca aggcctctgt caagacatca tctaccgtcc
    23641 gttcacgtga cttattggac tccatagccc aagtgtctgg gttgtggcaa tactggcaac
    23701 gcatgtgaca gccctgcaaa aagacaataa agcgaatacc aggcccatct actgacccaa
    23761 agctttctgt cgaatgcacc attcctgtca cttgtccata atcaattgtt tcttcagaca
    23821 tatcgttacc ttccttgaaa acgttttata gttttattat atcacgactt gaaggaaaaa
    23881 caagattttt gcctattttt tagaaagcaa tctgtttttc aatttcattt tcaatctatt
    23941 atcagattat tcttcaaaat cgaagccata taaggttgca aaatagtcct cagggcgctc
    24001 tgcacggcgg atttgacggg ctttaccttc ttcggtatag aggatttccg cagaacgtaa
    24061 tttggcatta tactggtagc ccattgaaaa tccgtgggca cctgtatcat gaattaccag
    24121 caaatcaccg atttctgtat gaggcagttc gcgattgact gcaaatttat cattgttttc
    24181 acagagtgaa ccaaccacat ctaccgcttc agctggtcca tctggatggg tcacgttgct
    24241 aatatgatgg taagctccgt acatagctgg acgcatgagg ttgactgctg aggcatccac
    24301 acctagatag gtacggtagg tttccttctt atgagtcact cttgtgacta gagcaccgtg
    24361 aggtgccagc ataaaacgac ccaattcggt gaaaatcttg acctggccaa gacctgctga
    24421 cgtaagaact tcttcataca ccttacgaac tccctcacca atcaaggcga tatcgttcgg
    24481 ctcctggtct ggacgataat taacaccaat accgccagaa agattgataa agtctagcca
    24541 aatgcccaac ttttccttga tttcaacagc cagttcaaag agctgacgag ccaactctgg
    24601 ataatagaga tgggtcacgg tattggacgc taggaaggag tgaatcccaa aagtcttggc
    24661 tcctttttcc ttcaagatag caaaggcttc aaagagctgg tccttggtca tgccaaactt
    24721 agcctcccca ggattgtcca taatgtctgt ccccagttca aaaacgcctc caggattata
    24781 acgacaagag atgatttctg gaatgcctgc tactctctcc agatgttcaa tatcttcaaa
    24841 ggcatccaag ttaatggtcg cacccaattc acgtgcatag gcgtattcct tgtctggcgt
    24901 gttgttggaa gagaacataa tctcagaacc cagaaagtcc agtttatggc tcatcaaaag
    24961 ctctacataa ctagagcagt ccacaccaca accttcttct tggagaattt tcaaaatagc
    25021 tggagttgga gtagccttaa ctgcaaaata ttccttaaag cccttgttcc acgaaaaagc
    25081 ttggttgacg gctcttgcct tctcacgaat ccccttctca tcatacaagt gaaagggagt
    25141 cgggaactcg gcaacaatcg cttctaactc ttctctattg ataaatggtg ttttcataag
    25201 cttccttcta ttctgtttgc aaagaaaggc tgggacaatc gttccaacct ttagttctat
    25261 ctcttattta tcttcgtcaa agatattgcc aacctcaaca tcgatggctt ggttcttgac
    25321 atcaatatta gttaccttca agagtgagtt gtagtcaaac tgcttttcac gttcttcttg
    25381 ggcattgtcc gcaaagaccg ctacacctgc cagttctgag tcgaactcgc gcaagagact
    25441 aatcataccg ttgaccgttc cgccaccttt caagaagtca tccacaatca agacacggct
    25501 gcctgcctta agactacgtt ttgaaaggaa cattttctcg atacggtcac cacttgaacc
    25561 tgaaacatag ttgacgctaa cagttgaacc ttcggtaatt ttcaggtcac ggcgcacaat
    25621 gacaaaagag acattgagga cattggcaac tgcatttgca agtggcacac ccttagttgc
    25681 tacggtcata accgcgtcaa ttttttggtc cataaagctt ttggcaataa tacgaccaat
    25741 atttttcaag atggctggtg tgctaagcaa atcagacaga tagatataac cacctggcaa
    25801 gatacggtca ctttctgaca acttggtacg caagtcttca accatttcct tagcatcctg
    25861 actcgaaata gacggtgtga agatgacacc tccgccagcc ccagtcactg tctggatatg
    25921 accgatttca atttcctcaa aggcgcgttt gataatgacg atatcttctg agatggatga
    25981 tttagcagac tcatactttt cagcaaaagt attgagacta gttagtttat aaggattatt
    26041 aatcaaatag ttggaaatga caaccatccg atcacttctt cttaatttca tttctatttc
    26101 ctattccatt tttattcaaa aaatcaaaaa gcaaactaga aagctggtcg ctggtggttc
    26161 aaaacactgt tttgagattg tcgatagaac tgacaaaccc tgtaatatac ctgcatatat
    26221 acatacgaca aagcgatact accctagttt gaagagattt tcgaagagta ttcatttttg
    26281 tcttttactt attataccat attcacataa aaaaacgaac attcttatcc taaaaaatgc
    26341 tcatttttct taaattatca atctaaatct ggtttataga aggaacgatt atccatagcg
    26401 aagattttat tggtcatctc tcctttatcc accaaagcca gagctgttga catcatcatc
    26461 atgcttgcat ccagattgtc aatcatatgg ataatctctg cctccataat acgtggacgg
    26521 actggacttc catattcaag caagccgtgg tgactgagga tgacatgacg aagcaaaacg
    26581 acttcttcct tggtatcatc gatgccgagt tccataactg tcttggtaat ttcgctatca
    26641 atgagagcga tatgtccaag aagattacct cgcactgtgt actctgtctg gtctggcccc
    26701 gtcaactcga tgaccttagc caagtcatgc aacataatcc ccgcatagag caggctctta
    26761 ttgagctgag gataaacttc gctaatagcg tctgccaaac gcaccatggt cgccgtatga
    26821 taggccaagc ccgtttcaaa ggcatggtgg ttggtcttgg cagctggata ggagtagaat
    26881 tccttatcat acttggtgta gagatttcgg acaatccgtt gccagacagg attttcaatt
    26941 ttgaaaatca tttgcgacat gtagtcacga atttccttga catcaactgg tgacttgacc
    27001 ttgaaatcag ctgggtcatt gggttcacca gcttgaggca ggcggagagt aatttgattg
    27061 acttgagggg tattgttata aacttctcgg cgtcctttca tgtggacaac cttacctgcg
    27121 gtaaaggcct caatgttatg aggttgggca tcccagagct tcccatcaat ctcgccacta
    27181 tcatcttgga aggtaaaggc taggtagttt ttcccagctc gagtttgcct caggtcagct
    27241 gatttgatta ggtaaaagcc ttcaaataac tcatcttttt tcatgtgact aatcttcata
    27301 ttcttcctca ttttcttgaa aatagagtag atcaagcgca ggctcacctt ctgacaactc
    27361 aatgtgacgg agcgtccgct cgatagctat ggtacgacgg tttaataatt catcaatatt
    27421 gccagaggca tgttggagat gtttttgtgc cttgaccaga ataccaccaa acttgccaaa
    27481 ctcggtcttg acactggcaa gagtcttgct gatatggtcg gcactctttt ggatattaag
    27541 ggtcttgaaa ccaactgata gggagttaag aagggctgat agggtacttg gtcctgcaac
    27601 aataatctgt tcttcccgtc tcaaatcatc aaagaagacc ggattgcgca caatctctga
    27661 ataaagacct tctgtcggaa caaacaagat tccaaagttg gttgtccgag gcggtgctat
    27721 gtacttgctc ttgatatcct tggcaaagcg cttgacgctt gctaggagtg acttacgaca
    27781 gcgttcaatc tcatccttgt cacctgtctc ataggcttct tccaagcggt aataatctgc
    27841 cagtggaaac ttagagtcaa ttggaagata gacgtattct tggtcgcctt gtccgggtaa
    27901 cttgatggca tactccactc gttcactaga gttttcaacc gttgcgtatt ctcgttcgta
    27961 ctgggcaggt gtcatgatgt cttcaataat ttgccccagt tgcaattctc ccagaatccc
    28021 tcgcgtcttg gttccagaga gaaccttgtt aagagctccg acatcacggg caactgtctg
    28081 catttctcca agaccacgat tgacagactc cagttgttta gaaactgtct caaaggaagc
    28141 ctgtaagcgt gtctgcaagg tcttttctag tttttcctcg accgtctggc gcatttgttc
    28201 caaacgttgc tcatttgatt cctgcaaggc ttggagacgt tggtctgtct tatctctagt
    28261 ttggaggaga ttatctgtca tttcttgacg gacttgggtc aggccttggt gcaattcaat
    28321 ccgcacttct tgcaaacggt cgctgacagc cacttccaaa tctttttggt ctaactggct
    28381 ggcttgtctg gcttggtcaa agcggtaatc caactggtct gacaaatgat ctgcctgatc
    28441 ctccaagctc ttacttaagt gtttctcctg cctatcctgc ctttgccaaa tcagaaagag
    28501 accagctagg ttggcaatta ataatagaat aagtaaactt tccatcctac ctcctatcct
    28561 tgctatgcag tacgaccaca taaccatctg ggcaagttac cgacacttcc ctatctatat
    28621 attcgttaga agcgtacact tttttaaaga aaaaattttc ctctgtcaac tcatacttgg
    28681 ctccaagaat agtcagctgg ctatcccgaa ctggcataaa ggctagatag tcgtagtctg
    28741 aacgaggttc tagctgactg gtcccttctg gacaataagt aatcaagttt tgcccatcct
    28801 caatttctat ttgatgcata tagggtgcca acttaggatt gctaggcaga aagacattgg
    28861 ccaacatatg gtcaatacgg ccacccaagg caccgaaaat agtaacctga gcctgaggat
    28921 ttttctcaaa gatggttaag agagccaatt ccaaatcggt atcatctttt tctggtcggg
    28981 cttggacaaa atactgggca cgtttttgaa tcacctgtcg ctcttcttcc gtcacagaat
    29041 caaaatctcc gactgctaga gcaagaggta agtcttcttc caagacccag agcgagcctc
    29101 gatccacccc aacaaaagca tcaaaatctg tccgataatg accgcggttt ccgcctgcaa
    29161 aaactgcaac cctagtccag ttgttttctg agagtttgta ctcgctcatt gacttctccc
    29221 ttaaagacat aggaacctgc tacaaaaaca gtcgcaccag cttctttggc ttgagcaata
    29281 gtttggtcat caatcccacc atccacttcg atttcaaagt tcaaaccttt ttcctcacga
    29341 agagcaacca actcacgaac cttatccatg gtttctggca gaaaggcttg cccaccaaaa
    29401 cctggattaa ccgtcatgac taaaacttgg tcaactagat gaaggacgtg cttgatggct
    29461 tcaactggtg tgccaggatt gataacgact gaaggcttaa ctccgagtga acgaattttt
    29521 tggagggcgc catgaatatg aggtgttgct tctacatgga tactgatgat gtctgcacct
    29581 gcacgcgcaa aatcttccag atgatgctca gggtttgaca ccatcaagtg gcaatcgaaa
    29641 accatcttac tatgaggacg aaggctctcg accacacctg caccaaaact gatttgcggt
    29701 acaaaatgac tgtccatgat atcgatatgg gcatattctg ccccagttgc ttctagacgt
    29761 ttgatttcac gttcaaagtt ggcataatct gctgccagaa ttgacggagc aatcttgtat
    29821 tgagacatag gtttctcctt attttggaat ttttttgctg acttttttat aggtttctct
    29881 acgattttca atttcactaa ggaattgcag gtaattgtca aaacggaagg ttgcaataac
    29941 accctcttca acagctggtt tgacggcaca agacggctca tgggtatggg tacaagtacg
    30001 gaacttacaa tctcggctaa cagtagcaat ctctgggaaa gcctgattga ggtcttcagc
    30061 ccttgatact tcatagtcca aggatgaaaa tcctggtgta tctgcgattt tacccccgtt
    30121 gagattgtaa aaactaacag ctcgagtggt atggcgaccg cgacctagac tgtctgaaat
    30181 ttctcccgtt tcaagattga ggtctggtgc gattttattg agaagagttg acttcccaac
    30241 acctgtctgc cccataaaga ccgtaacctt gcctgttaac aaagacagga gttcctcttt
    30301 actggtcaca aagtcatagc cgatgtcacc ataggtctgc tggtaaaaat ccagttctcc
    30361 cctatcttcc aacaaatcca ttttggaaat atagacaatg ggatggatgc ccttgtgctc
    30421 caaaagaacc aagaaacgat ccagcaaatt gctgttaaaa tcaggttcct tgacggacat
    30481 gattactaca gcttggtcga tattgacaat aggcggacgg accagactgt ttttccgttc
    30541 gtgaatcttg agaatatagc cttctgaatt ttcctcggca gagaaatcta cccagtcccc
    30601 aacgtaaggg gtatgccctt ttttacggaa attcccacgc gcgcgtgttt gatagacttg
    30661 gccatcactc tctacatagt agaacccagc caaggcttta atgatttgtc cctgcatctt
    30721 agagtccttg ccctttaagt gcgtctgcta gaccggcaaa ttctgccaag ctgagagctt
    30781 ccccacgcac acttggcgac aagtctgcct ggtccaaagc cttggtcagc ttgtccttga
    30841 cttcctcagt cttgccaaag taacctgtca agttattcca caaggtctta cggcgatggg
    30901 taaaactagc cttggaaacc ttaaagaaga agttctcatc ttccactgct acagctggct
    30961 ctggacggcg caccattttc aagatggctg aatccacatt tggcgctggc acaaagaccg
    31021 tacgaggcac gataaaggca accttggctg tcatgtaata ctgcacggcg atagacaagc
    31081 taccgtaagc cttggtgtta ggctgggctg aaatgcggtc cgctacttct ttctgcatca
    31141 tgaccacaaa ctcactaaaa ggaatgccac tctcaatcaa gtgcatgaga ataggcgtcg
    31201 tgatgtagta aggcaaatta gccactacct tgattggcag gttaggattt ttaaaatttt
    31261 ggatatgttg cgccaaatca accttgagaa tatcttcgtt aactacagtc acattatcaa
    31321 aatcacgcag ggtatctgcc aaaattggca ccaaacggtg gtcaatctca aaagccatga
    31381 cttgggctgc acgctcagcc aaaaattctg tcaaggcacc aatacctggc ccgatttcga
    31441 tgacattgac ctgatcatca atttcagccg tatccacaat tttttgaagg atattggtat
    31501 ccgtcaagaa attttgccca aaggactttt taaaggtaaa accgtgacgc tccaacactg
    31561 ccttggtcac gctataatct gcaattctca tctattctct tttctattat ctgttactac
    31621 tattgtaaca cattcccctt gtattttggg aatgaaaatc ataccaaaaa actatctttc
    31681 ctcatgaaga aagatagtct tggaaatctt taaaagtggc cttaacagtt ctctcgaaac
    31741 atgcgttcaa aaaaatcagc ttcttgataa cttcgatttt cgggtagggt caaatccaca
    31801 tcctcctcca catcatccac tgtcagttca accgtctgag gtaaattttt caaacgataa
    31861 tgcttttgcc tttgcccttc aatactagca aaatcaagca aatagccatg cactcggatt
    31921 tgaaccaaaa ggagatgatt ggtcatattt tccatgatga ggatatcttc taaaccacct
    31981 ctggcactag gataatcaga taccctgcga atacggattt tttcacacat gagcaagttt
    32041 cctcatatca atgatttcat cagccttatt ccagactagg ggattatggg tcgcaatgat
    32101 gataattcga ttttcatctt tcaaatccac caagagattc ataacctcct ctgaattttc
    32161 aggatcaaga gctgctgttg gttcatctgc caaaatcaag ggtggatttt tcaaaatagt
    32221 ttttgcaagg gcaactcgtt gggcctctcc cccagataaa gtataaattt tttgttctaa
    32281 atccaaatac cctagattaa ctttttctaa agcccccact tgcctttcca aacgttctac
    32341 ttttgagatt ttctgaccaa caaaacccaa atccaaattt tctttgattg attggttttc
    32401 taagaggcca aaattttgaa agagatagcc catctgatct cgaaaatact cacgagtggg
    32461 aatggttttt aaatctttcc cctgatagag aacccttcct ccatctatct tttctagctt
    32521 tcccaagata ttcagcagcg tcgtctttcc gcttccactc tttccgatta aggcataaac
    32581 cttgcccttc tccagcttga gattcaaacc agagaaaatc gcgcggtcat taaatttctt
    32641 ttccaatcct tgaatatcaa tcatcttatt ttcctttcaa tactgccatg ctaccagctt
    32701 cttctttttt gtcctgcctt actaaaatca agagggcgtt aagcgtaaac aaagctacaa
    32761 ctagagcgct aatcaaacca tctcttgtca aaatactaga taggactagg ccaagcaaga
    32821 gaactcctcc ttgcgccagt aaatacttgc catgaagctc atagattgtc ataccagcaa
    32881 gacgtttaat cataagatcc cgtctgaact gctcaaaata gagaagattc atggaatcaa
    32941 ataacaagat agccgtagac agggtcaaaa tcgtcccaat aaggagagag taaaactcca
    33001 cccgtttgtc atttagtacc ttggcaaaaa atagctggct ttttaccaag taagaaacct
    33061 tgtgatacag accttgctct tttagagctg tgatgctgtc tccatatcga tctagtttca
    33121 aggcactatt agccgtagtt ccccacaaca tccctgcaac aggtcttgtt ccagtcgctt
    33181 gcggcgttag aactacaata atcggatctt ttaggtactg gcgtgttgtc ttgtacccat
    33241 cattatagag gaaacgttcc tgtcctattt ctgtaaaagc tagccttacc tgtgggaggt
    33301 agtgtttctg actcgtcact tctacacttt cagatgaaaa gttttgcagg taatctgtaa
    33361 acaatccttg gtagtagata gactgctctc gcaagctctc aggcaagatc agcccaaact
    33421 ctccctcaga caagttttgc atcttgtcca taaactctga agaaacggta atcttttctt
    33481 ctatcagata gcgcggtgag acatagataa cattccctga cggtgtgtag tcactgagac
    33541 gattgccatc taggtccact tctgctccat ctgagaaatt gtcaacattg ctcataatat
    33601 aaaaagagtc tgtattggct aaccgttctt cagtaaatgt ctgccactca cgattatcct
    33661 tacgcgttcc ttcttcatcg gcaaatgcac tagaccaacc aaaggataga cggtaacggt
    33721 ctgaggactg gctccattta ttgctagctc tctccatttc ctgcatttca cggtagtggg
    33781 gtaggagagc tgtcgcactc gatccgacca ccaatacagc taagagttgc cccaccatca
    33841 tcaatgtcat catacgtttg agagggagtt tccctttcaa tagatccacc agactatttt
    33901 cctgtaaacc aagtagatag acgacactta gtaaggtaga aatccctgcc aaggtcaatc
    33961 cataaagtag aagagcaatg atgaccagtt gcaccgttgc cataaacaag gcaccttgat
    34021 accagagaat ccccaatccc aaaagactgg ataccagcac tgagcagata agctgtctca
    34081 catcttctaa cactggtctg agagcaactc caaacaagct ctcaccagct attaagcgaa
    34141 tccctgcctg acgaagggat ttgatccgat aaatcagggt cagactcata aaggtcagca
    34201 gaaaaatagc taaactcagt agcaccatag gggtggccgt caatagtaag actatcgaaa
    34261 atggatcttc tccattcgaa acaaagcctt gataaccaag ctctttcaag gtggtctgta
    34321 agctcactcc atccaaactt cctgatacaa tcaagtaaga ccctaataaa tcactcgttt
    34381 ctgcactctc cttggaggaa atggtcagac cttctggaag ctttccctca ccataagtgg
    34441 cataggtaaa gcgtgtttct ccagcttcat ttggctcaac gattcgacga gcaatgagac
    34501 tattgtgctc taccgccaag tgactcaaag cctctgtcac ctcttcgcga ctagctactg
    34561 gttgatttat catcattcct gtcacatcaa cagaaggata gttaccaaat aaaatctctt
    34621 ctcgatggtc aacggaagtt atcaccatat aaagcgatac taataccatt gaaatcaaaa
    34681 taaataaacg tttcatcatt tcctccaaaa agttacttgg tcacttagtg agaaggtgac
    34741 caagtaaagc taaacaatag ggctatacca ttctaaacat tatagtagaa tgcaactttc
    34801 tctccccaag aagtacgaat ccatgcacga gaagtccctc cagcaccagc atatcccttg
    34861 tcagatgaac cagtttttct gctaacaact gttgaactat ggtattttga agggtgatag
    34921 tagtttgagt aagcaccacc gttacctgaa ccataagtcc aaacaccacc ttctgggtat
    34981 tgaacggctg cagaggcaac tgctacactt ccacctaatg ttgctgcaat gctcgctaca
    35041 agagctaatt ttttaactgt ttgtttcata ttgatactcc tctatttttg attacaagat
    35101 tgttgagtta cttgctcctc tttccattat caacgttgat actattatat taccaaatga
    35161 tattctaaaa ttatttgttt ttctctaaat tgtcaaaata gcaccctgaa atgaactttt
    35221 atagtcatta tactccatct ttatcacact atcaaggaca tcaatgtcct taaaatctaa
    35281 ctatttcata ttatttttag cttatatcta aaaaaacagt tctaaagacg aactttagaa
    35341 ctgttttgat acgaggacaa ggacattttt gtcactgatt cactatgttt a
//
LOCUS       DAVLGK010000021        34401 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLGK010000021 DAVLGK010000000
VERSION     DAVLGK010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34401
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.021"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            553..1005
                     /locus_tag="VXE01_001115"
     CDS             553..1005
                     /locus_tag="VXE01_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0750024.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1024..2361
                     /locus_tag="VXE01_001116"
     CDS             1024..2361
                     /locus_tag="VXE01_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0750025.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLGSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2440..3324
                     /locus_tag="VXE01_001117"
     CDS             2440..3324
                     /locus_tag="VXE01_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0750026.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3324..4157
                     /locus_tag="VXE01_001118"
     CDS             3324..4157
                     /locus_tag="VXE01_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0750027.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4175..6268
                     /gene="nanB"
                     /locus_tag="VXE01_001119"
     CDS             4175..6268
                     /gene="nanB"
                     /locus_tag="VXE01_001119"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV0750028.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVREKGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFENATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6280..7383
                     /locus_tag="VXE01_001120"
     CDS             6280..7383
                     /locus_tag="VXE01_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0750029.1"
                     /translation="MVKYGVVGTGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7557..8255
                     /locus_tag="VXE01_001121"
     CDS             7557..8255
                     /locus_tag="VXE01_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0750030.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8274..9791
                     /locus_tag="VXE01_001122"
     CDS             8274..9791
                     /locus_tag="VXE01_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0750031.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9916..11244
                     /locus_tag="VXE01_001123"
     CDS             9916..11244
                     /locus_tag="VXE01_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0750032.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11496..12362
                     /locus_tag="VXE01_001124"
     CDS             11496..12362
                     /locus_tag="VXE01_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0750033.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12378..13217
                     /locus_tag="VXE01_001125"
     CDS             12378..13217
                     /locus_tag="VXE01_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0750034.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13489..13941
                     /locus_tag="VXE01_001126"
     CDS             13489..13941
                     /locus_tag="VXE01_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0750035.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYASMEEKVRKYLFKILID"
     gene            14083..14391
                     /locus_tag="VXE01_001127"
     CDS             14083..14391
                     /locus_tag="VXE01_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750036.1"
                     /translation="MDGQGITVDEMAWIIRGIVNALIGRYIKLGTYAAKYGISMARSI
                     LNRAAATAAERVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDAHDKIPNNGRINF
                     "
     gene            14678..15322
                     /locus_tag="VXE01_001128"
     CDS             14678..15322
                     /locus_tag="VXE01_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0750037.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEIKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15491..16408
                     /locus_tag="VXE01_001129"
     CDS             15491..16408
                     /locus_tag="VXE01_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV0750038.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16426..17310
                     /locus_tag="VXE01_001130"
     CDS             16426..17310
                     /locus_tag="VXE01_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0750039.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17326..18177)
                     /locus_tag="VXE01_001131"
     CDS             complement(17326..18177)
                     /locus_tag="VXE01_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0750040.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18377..20434
                     /gene="pbp2b"
                     /locus_tag="VXE01_001132"
     CDS             18377..20434
                     /gene="pbp2b"
                     /locus_tag="VXE01_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV0750041.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSELTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20445..21041
                     /gene="recR"
                     /locus_tag="VXE01_001133"
     CDS             20445..21041
                     /gene="recR"
                     /locus_tag="VXE01_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV0750042.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21217..22260
                     /locus_tag="VXE01_001134"
     CDS             21217..22260
                     /locus_tag="VXE01_001134"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV0750043.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22344..23717
                     /locus_tag="VXE01_001135"
     CDS             22344..23717
                     /locus_tag="VXE01_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV0750044.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLAAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELGITDLVERKDSLTFKVNFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            23704..24315
                     /locus_tag="VXE01_001136"
     CDS             23704..24315
                     /locus_tag="VXE01_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0750045.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKFLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24406..25110
                     /locus_tag="VXE01_001137"
     CDS             24406..25110
                     /locus_tag="VXE01_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV0750046.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25329..26702
                     /gene="ftsA"
                     /locus_tag="VXE01_001138"
     CDS             25329..26702
                     /gene="ftsA"
                     /locus_tag="VXE01_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV0750047.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26719..27978
                     /gene="ftsZ"
                     /locus_tag="VXE01_001139"
     CDS             26719..27978
                     /gene="ftsZ"
                     /locus_tag="VXE01_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV0750048.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27983..28654
                     /locus_tag="VXE01_001140"
     CDS             27983..28654
                     /locus_tag="VXE01_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV0750049.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28664..29203
                     /locus_tag="VXE01_001141"
     CDS             28664..29203
                     /locus_tag="VXE01_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV0750050.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29203..29466
                     /locus_tag="VXE01_001142"
     CDS             29203..29466
                     /locus_tag="VXE01_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV0750051.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29463..30248
                     /locus_tag="VXE01_001143"
     CDS             29463..30248
                     /locus_tag="VXE01_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV0750052.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVFSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30257..31045
                     /gene="divIVA"
                     /locus_tag="VXE01_001144"
     CDS             30257..31045
                     /gene="divIVA"
                     /locus_tag="VXE01_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV0750053.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31393..34185
                     /locus_tag="VXE01_001145"
     CDS             31393..34185
                     /locus_tag="VXE01_001145"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV0750054.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAAVSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10568 a         6061 c         7489 g        10283 t
ORIGIN      
        1 ctaatttaga gaatgaaata tagagtattt ctctcttaaa agtttttggt gaaacgagat
       61 gtagaaagga gatttagcca aagagtctat tagtgctaga ataatagatt agaattattt
      121 tagaaaaacg aagtgagcag cttataaatt caagtcccca aatagattca tactagtatc
      181 ttttgcaaaa aataaagggc gacttccttc atgaatatca atttcatcta taaggaaggt
      241 agctaattga actaacttat ttattctgtt tgtcgctaga aaaatcagac ctccttgtga
      301 agattgagga gatactgaat gaaaatcaaa gaagaaacta gcaagctagt agcagattgc
      361 ccaaaacacc gctttgaggt tgtagataag actgacgtat ataatccaag gtgaagcgac
      421 tgtggtttga agagattttc aaagagtata ggctagagag tagtgttttt atgtccttct
      481 agtagaaaat gctagacaga agaatgggga acttggatag gaaaaataga ttgagaaagg
      541 aggttagaag agatgattat tacaaaaatt agccgtttag gaacttatgt gggagtaaat
      601 ccacattttg caacattaat agattttcta gaaaaaacag gactagaaaa tttaacagaa
      661 ggttcgattg ctatcgatgg taatcgattg tttgggaatt gctttactta tctagcagat
      721 ggtcaagcag gggctttctt tgaaacacac caaaaatatt tggatattca tttagttttg
      781 gaaaacgaag aagccatggc tgttacatcg ccggaaaatg taagcgttac ccaagaatat
      841 gatgaagaga aagatattga attatacaca gggaaagtgg aacagttggt tcatttgaga
      901 gctggcgaat gcctcatcac ttttccagaa gatttacatc aacccaaggt tcgtataaat
      961 gatgaacctg tgaaaaaagt tgtctttaaa gttgcgattt cttaatgtag aaagagaaga
     1021 acgatgaaaa aaatgagaaa gtttttatgt ctagctggaa ttgcgctagc ggctgttgcc
     1081 ttggtagctt gttcaggaaa aaaagaagct acaactagta ctgaaccacc aacagaatta
     1141 tctggtgaga ttacaatgtg gcactccttt actcaaggac cccgtttaga aagtattcaa
     1201 aaatcagcag atgctttcat gcaaaagcat ccaaaaacga aaatcaagat tgaaacattt
     1261 tcttggaatg acttctatac taaatggact acaggtttag caaatggaaa tgtgccagat
     1321 atcagtacag ctcttcctaa ccaagtaatg gaaatggtca actcagatgc tttggttccg
     1381 ctaaatgatt ctatcaagcg tattggacaa gataaattta acgaaactgc cttaaatgaa
     1441 gcaaaaatcg gagatgatta ctactctgtt cctctttatt cacatgcaca agtcatgtgg
     1501 gttagaacag atttgttaaa agaacataat attgaggttc ctaaaacttg ggatcaactc
     1561 tatgaagctt ctaaaaaatt gaaagaagct ggagtttatg gcttgtctgt tccgtttgga
     1621 acaaatgact taatggcaac acgtttcttg aacttctacg tacgtagtgg tggaggaagc
     1681 ctcttaacaa aagatcttaa agcagacttg acaagccaac ttgctcaaga tggtattaaa
     1741 tactgggtta aattgtataa agaaatctca cctcaagatt ctttgaactt taatgtcctt
     1801 caacaagcta ccttgttcta tcaaggaaaa acagcatttg actttaactc tggcttccat
     1861 atcggaggaa ttaatgccaa cagtcctcaa ttgattgatt cgattgatgc ttatcctatt
     1921 ccaaaaatca aagagtctga taaagaccaa ggaattgaaa cctcaaacat tccaatggtt
     1981 gtttggaaaa attcaaaaca tccagaagtt gctaaagcat tcttagaagc actttataat
     2041 gaagaagact acgttaaatt ccttggttca actccagtag gtatgttgcc aactattaag
     2101 gggattagcg attctgcagc ctataaagaa aatgaaactc gtaagaaatt taaacatgct
     2161 gaagaagtaa ttactgaagc tgttaaaaaa ggtactgcta ttggttatga aaatggacca
     2221 agtgtacaag ctggtatgtt aactaaccaa cacattattg aacaaatgtt ccaagatatc
     2281 attacaaatg gaacagatcc tatgaaagca gcaaaagaag cagaaaaaca attaaacgat
     2341 ttatttgagg ctgttcagta gatgtaaaag actagaaaat aggtgggcta gtgatctgaa
     2401 aagctctagc ccaatcttgt aaaagaaggg agaaggagaa tggttaaaga acgtaattta
     2461 actcgctgga tatttgtttt gccagctatg attatcgtag gattactctt tgtttatccg
     2521 tttttctcga gtatttttta tagctttacc aataagcatt tgattatgcc taattataaa
     2581 tttgttggtt tggctaacta taaagctgtg ctatcagatc ccaacttctt taatgcgttc
     2641 tttaattcaa ttaagtggac cgttttctca ttagttggtc aagttttagt agggtttgta
     2701 ttggctttag ctcttcacag agtacgccac ttcaagaaat tatataggac cttattgatt
     2761 gttccttggg catttcctac catcgttatt gccttttctt ggcagtggat tctaaacggg
     2821 gtttatggct acttacctaa tctaatcgta aaattaggtt taatggaaca tacacctgca
     2881 tttttgacag atagtacatg ggcattccta tgtttggtgt ttatcaacat ttggtttgga
     2941 gcaccaatga ttatggttaa tgtgctttca gctttgcaaa cagtaccaga agaacaattt
     3001 gaggctgcta agatagatgg tgcttcaagt tggcaggtgt tcaagtttat cgtctttcca
     3061 catattaaag tggttgtagg acttctagtt gttttgagaa ctgtatggat ctttaataac
     3121 tttgacatta tctacctcat tactggtggt ggaccagcca atgctacaac gacgcttcca
     3181 atttttgctt acaacctggg ctggggaact aaattgttgg gtcgtgcttc agcagttaca
     3241 gtattgctct ttatcttctt ggtggcgatt tgctttatct actttgctat catcagtaag
     3301 tgggaaaagg agggtagaaa ataatgaaga agaaatccag tatttattta gatattctct
     3361 cacatgtact tttagttggt gcgaccatcg ttgcagtttt cccattggta tggattatca
     3421 tatcttctgt caaagggaaa ggggaattaa ctcagtatcc aacacgattt tggcctgaac
     3481 agtttacatt agattatttc actcatgtta tcaacgattt gcacttcatt gataacattc
     3541 gaaacagttt aatcattgcc ttggctacaa cccttattgc gattattatt tctgctatgg
     3601 cagcctatgg tattgttcga ttctttccta aattgggagc aatcatgtcg agactactcg
     3661 tcattaccta cattttccca ccaattttgt tagcaattcc ctattcaatt gccattgcta
     3721 aagttgggtt aacaaatagt ttatttggct tgatgatggt ttatctatct tttagtgttc
     3781 catatgcagt ttggctctta gttggatttt tccaaacagt tccaattgga attgaagaag
     3841 cggctagaat tgatggtgca aataaatttg ttacgtttta taaagttgtg ctaccgattg
     3901 tagcaccagg tattgtagca acagctattt atacatttat caatgcttgg aatgaattcc
     3961 tgtatgcctt gattttgatt aacaatacag gaaagatgac agtagcagta gcccttcgtt
     4021 cacttaatgg ttcagaaata ctagactggg gagatatgat ggcagcgtct gttattgtag
     4081 ttcttccatc aattattttc ttctctatca tccaaaataa gattgcaagt ggattatcag
     4141 aaggatctgt gaagtagacg aaagaaggaa aaaaatgaat aaaagaggtc tttattcaaa
     4201 actaggaatt tctgttgtag gcattagtct tttaatggga gtccccactt tgattcatgc
     4261 gaatgaatta aactatggtc aactgtccat atctcctatt tttcaaggag gttcatatca
     4321 actgaacaat aagagtatag atatcagccc tttgttatta gataaattgt ctggagagag
     4381 tcagacagta gtaatgaaat ttaaagcaga taaaccaaac tctcttcaag ctttgtttgg
     4441 cctatctaat agtaaagcag gctttaaaaa taattacttt tcaattttca tgagagattc
     4501 tggtgagata ggtgtagaaa taagagacgc ccaaaaggga ataaattatt tattttctag
     4561 accagcttca ttatggggaa agcataaagg acaggcagtt gaaaatacac tagtatttgt
     4621 atctgattct aaagataaaa catacacaat gtatgttaat ggaatagaag tgttctctga
     4681 aacagttgat acatttttgc caatttcaaa tataaatggt atagataagg caacactagg
     4741 agctgttaat cgtgaaggta aggaacatta cctcgcaaaa ggaagtattg gtgaaatcag
     4801 tctatttaac aaagcaatta gtgatcagga agtttcaaat attcccttgt caaatccatt
     4861 tcagttaatt ttccaatcag gagattctac tcaagctaac tattttagaa taccgacact
     4921 atatacatta agtagtggaa gagttctatc aagtattgat gcacgttatg gtgggactca
     4981 tgattctaaa agtaagatta atattgccac ttcttatagt gatgataatg ggaaaacgtg
     5041 gagtgagcca atttttgcta tgaagtttaa tgactatgag gagcagttag tttactggcc
     5101 acgagataat aaattaaaga atagtcaaat tagtggaagt gcttcattca tagattcatc
     5161 cattgttgaa gataaaaaat ctgggaaaac gatattacta gctgatgtta tgcctgcggg
     5221 tattggaaat aataatgcaa ataaagccga ctcaggtttt aaagaaataa atggtcatta
     5281 ttatttaaaa ctaaagaaga atggagataa cgatttccgt tatacagtta gagaaaaggg
     5341 tgtcgtttat gatgaaacaa ctaataaacc tacaaattat actataaatg ataagtatga
     5401 agttttggag ggaggaaagt ctttaacagt cgaacaatat tcggttgatt ttgatagtgg
     5461 ctctttaaga gaaaggcata atggaaaaca ggttcctatg aatgttttct acaaagattc
     5521 gttatttaaa gtgactccta ctaattatat agcaatgaca actagtcaga atagaggaga
     5581 gagttgggaa caatttaagt tgttgcctcc gttcttagga gaaaaacata atggaactta
     5641 cttatgtccc ggacaaggtt tagcattaaa atcaagtaac agattgattt ttgcaacata
     5701 tactagtgga gaactaacct atctcatttc tgatgatagt ggtcaaacat ggaagaaatc
     5761 ctcagcttca attccgtttg aaaatgcaac agcagaagca caaatggttg aactgagaga
     5821 tggtgtgatt agaacattct ttagaaccac tacaggtaag atagcttata tgactagtag
     5881 agattctgga gaaacatggt cgaaagtttc gtatattgat ggaattcaac aaacttcata
     5941 tggcacacaa gtatctgcaa ttaaatactc tcaattaatt gatggaaaag aagcagtcat
     6001 tttgagtaca ccaaattcta gaagtggccg taagggaggc caattagttg tcggtttggt
     6061 caataaagaa gatgatagta ttgattggag ataccactat gatattgatt tgccttcgta
     6121 tggttatgcc tattctgcga ttacagaatt gccaaatcat cacataggtg tactgtttga
     6181 aaaatatgat tcgtggtcga gaaatgaatt gcatttaagc aatgtagttc agtatataga
     6241 tttggaaatt aatgatttaa caaaataaag gagaaaaaca tggttaaata cggtgttgtt
     6301 ggaacagggt attttggagc tgaattggct cgctacatgc aaaagaatga tggagcagag
     6361 attactcttc tctatgatcc agataatgca gaggcgattg cagaagaatt gggagcaaaa
     6421 gtagcaagtt ccttagatga gttggtttct agcgatgaag tagattgtgt tatcgtcgca
     6481 actccaaata atcttcataa ggaaccggtt attaaggctg cacagcatgg taaaaatgtt
     6541 ttctgtgaaa aaccaattgc gctttcttat caagattgtc gcgagatggt agatgcgtgt
     6601 aaagaaaaca atgtaacctt tatggcagga catattatga atttctttaa tggtgttcat
     6661 catgcaaaag aactcattaa tcaaggagtt atcggagacg ttctatattg tcatacagct
     6721 cgtaatggtt gggaagaaca acaaccgtca gtatcatgga aaaaaattcg tgaaaaatca
     6781 ggtggtcact tgtatcacca catccatgaa ttggattgcg ttcaattcct tatggggggc
     6841 atgcctgaaa ctgtaaccat gacaggtgga aatgtggccc atgaaggtga acatttcggt
     6901 gatgaagatg atatgatttt tgtcaatatg gaattttcta ataagcgttt tgccttgtta
     6961 gaatggggtt cagcttatcg ttggggtgaa cattatgtct taatccaagg aagcaaaggt
     7021 gccatccgct tagacttatt caactgtaaa ggaactctta agctagatgg gcaagaaagc
     7081 tatttcttga ttcacgaatc gcaagaagaa gatgatgatc ggactcgtat ctatcatagt
     7141 acagagatgg atggagcaat tgcttatggt aaaccaggta aacgtactcc attatggcta
     7201 tcatctgtca ttgataaaga aatgcgctat ctgcatgaga ttatggaagg agctccagta
     7261 tcagaagaat ttgcaaaact tttgacaggt gaagctgccc tagaagcaat tgctactgca
     7321 gatgcttgta cccagtctat gtttgaagat cgcaaagtaa aattgtcaga aattgtaaaa
     7381 taaattttgg tattctccta tttataggtc gacttgctcc tctgaaagta cttttagagg
     7441 agctgtttga ctttgctagt ttttgaaact gaaatctatt atactacaaa ctattgaaag
     7501 cgttttaatt ttaaggtata ataatctcat agaaataaag aaaaggagga aagaggatgc
     7561 cacagattag caaagaagcc ttgattgagc aaatcaaaga tggaatcatc gtttcttgtc
     7621 aggctcttcc tcatgaaccg ctttatacag aagcgggagg ggtgattccc ttgctggtca
     7681 aagcggctga gcaaggtgga gcagtcggta tccgagcaaa cagtgttcgc gatatcaagg
     7741 aaattaagga agtcactaaa cttccaatca ttgggattat caaacgtgat tatccacctc
     7801 aggaaccctt catcacggct actatgaaag aagttgatga attggcagaa ctggacatcg
     7861 aggtgattgc tctggattgt accaagcgtg aacgctacga tggtttggaa attcaagagt
     7921 tcattcgtca ggttaaggag aaatatccta atcagctttt gatggctgat actagtatct
     7981 tcgaagaagg gctagcagct gtagaagcag gaattgactt tgtcggaaca accttatcag
     8041 gctacacatc ctacagtcca aaagtagacg gtccagattt tgaattgatt aagaaactct
     8101 gtgatgctgg tgtagatgtc attgcagaag gaaaaattca tacaccagaa caagccaaac
     8161 aaatccttga atatggagtg cgaggcatcg ttgttggtgg cgccattact agaccaaaag
     8221 agattacaga acgcttcgtt gctagtctta aataagatgt gagggggagt tttatgttta
     8281 aagttttaca aaaagttgga aaagctttta tgttacctat agctatactt cctgcagcag
     8341 gtctactttt ggggattggt ggtgcacttt caaacccaac cacgatagca acttatccaa
     8401 tactagacaa tagtattttt caatcaatat tccaagtaat gagctctgca ggagaggttg
     8461 tattcagtaa tttgtcacta cttctctgtg tgggattatg tattggctta gcgaaacgag
     8521 ataaaggaac cgctgcgtta gcaggagtaa ctggttactt agttatgact gcaacgatca
     8581 aagctttggt aaaacttttt atggcagaag gatctgcaat tgatactgga gttattggag
     8641 cattagttgt cggaatagtt gccgtatatt tgcacaaccg atataacaat attcaattac
     8701 cttccgcttt aggattcttt ggaggttcac gcttcgttcc tattgttaca tcgttctctt
     8761 ctatcttgat tggctttgtc ttctttgtta tttggccacc tttccaacaa cttcttgttt
     8821 ctacaggtgg atatatttct caggcgggtc caattggaac ttttctatat ggatttttaa
     8881 tgagactttc tggagcagta ggcttacatc atataattta ccctatgttt tggtatactg
     8941 aacttggtgg tgttgaaact gttgcaggac aaacagtggt tggagctcaa aaaatatttt
     9001 ttgctcaatt agccgatttg gcccattctg gattatttac agaaggaaca aggttttttg
     9061 caggtcgttt ctcaacaatg atgttcggtt taccggctgc ctgtttagcg atgtaccata
     9121 gtgttcctaa aaatcgtcgt aaaaaatacg cgggtttgtt ttttggagtt gctttaacat
     9181 cttttattac cggtattaca gaaccaattg aatttatgtt tctattcgtc agtccggttc
     9241 tatatgttgt tcacgcattc cttgatggtg ttagcttctt tattgcagac gtcttaaata
     9301 tttcaatagg aaacacattt tcaggaggtg taatcgattt cactttattt ggaattttgc
     9361 aggggaacgc taagacgaat tgggttcttc agattccatt tggacttatt tggagtgttt
     9421 tgtattatat tatttttaga tggttcatta ctcaattcaa cgttctaacg ccagggcgag
     9481 gagaagaagt agattctaaa gaaatttctg aatccgcaga ttcaacttca aatactgcag
     9541 attatttaaa acaggatagc ctacaaatta tcagagcctt gggtggatca aataatatag
     9601 aagatgtaga tgcttgtgtg acacgtttac gtgtagctgt aaaagaagtt aatcaagttg
     9661 ataaagcact tttaaaacaa attggtgcag ttgatgtctt agaagtgaag ggtggcattc
     9721 aagcaatcta tggagcaaaa gcaatcttat ataaaaatag tattaatgaa attttaggtg
     9781 tagatgatta agtacttact gacttaataa aaaacagagg agagtgatgg atgagtagga
     9841 tgaaatgaaa tcgcatacaa gaaataaaga actcattatc caagttggat acgcttatta
     9901 cataggagaa tacaaatgaa atttagaaaa ttagcttgta cagtacttgc gggtgctgcg
     9961 gttcttggtc ttgctgcttg tggcaattct ggcggaagta aagatgctgc caaatcaggt
    10021 ggtgacggtg ccaaaacaga aatcacttgg tgggcattcc cagtatttac ccaagaaaaa
    10081 actggtgacg gtgttggaac ttatgaaaaa tcaatcatcg aagcgtttga aaaagcaaac
    10141 ccagatataa aagtgaaatt ggaaaccatc gacttcaagt caggtcctga aaaaatcaca
    10201 acagccatcg aagcaggaac agctccagac gtactctttg atgcaccagg acgtatcatc
    10261 caatacggta aaaacggtaa attggctgag ttgaatgacc tcttcacaga tgaatttgtt
    10321 aaagatgtca acaatgaaaa catcgtacaa gcaagtaaag ctggagacaa ggcttatatg
    10381 tatccgatta gttctgcccc attctacatg gcaatgaaca agaaaatgtt agaagatgct
    10441 ggagtagcaa accttgtaaa agaaggttgg acaactgatg attttgaaaa agtattgaaa
    10501 gcacttaaag acaagggtta cacaccaggt tcattgttca gttctggtca agggggagac
    10561 caaggaacac gtgcctttat ctctaacctt tatagcggtt ctgtaacaga tgaaaaagtt
    10621 agcaaatata caactgatga tcctaaattc gtcaaaggtc ttgaaaaagc aactagctgg
    10681 attaaagaca atttgatcaa taatggttca caatttgacg gtggggcaga tatccaaaac
    10741 tttgccaacg gtcaaacatc ttacacaatc ctttgggcac cagctcaaaa tggtatccaa
    10801 gctaaacttt tagaagcaag taaggtagaa gtggtagaag taccattccc atcagacgaa
    10861 ggtaagccag ctcttgagta ccttgtaaac gggtttgcag tattcaacaa taaagacgac
    10921 aagaaagtcg ctgcatctaa gaaattcatc cagtttatcg cagatgacaa ggagtgggga
    10981 cctaaagacg tagttcgtac aggtgctttc ccagtccgta cttcatttgg aaaactttat
    11041 gaagacaaac gcatggaaac aatcagcggc tggactcaat actactcacc atactacaac
    11101 actattgatg gatttgctga aatgagaaca ctttggttcc caatgttgca atctgtatca
    11161 aatggtgacg aaaaaccagc agatgctttg aaagccttca ctgaaaaagc gaacgaaaca
    11221 atcaaaaaag ctatgaaaca atagtcctta gttattctat aaaaagtagt tttttaaaga
    11281 acctaagagt gtataccccc ttttccctct acacagatag tgtaagaaaa gggggctttt
    11341 gtttaaaatg taagaaactg tcacgaaatt aaaatgaagt tcttacataa gcgaatcata
    11401 aaaaatttca ttttgatttt aaaacagttc aagaaagtca aaaaattatt ctatttgaaa
    11461 gagaggtgcc gactgtgaaa gtcaataaaa tccgtatgcg ggaaacagtg atttcctacg
    11521 ctttcctagc accagtatta ttcttctttg tcatctttgt gttggctccg atggtgatgg
    11581 gcttcattac aagtttcttt aactactcaa tgactaaatt tgagtttgta ggcttggata
    11641 actatatccg tatgtttaaa gatcctgtct ttacaaaatc tctgattaac acagttattt
    11701 tggttattgg atctgtacca gttgttgttc tattctcact ctttgtagca tctcagacct
    11761 atcatcaaaa tgtcattgcc agatccttct accgtttcgt cttcttcctt cctgttgtaa
    11821 cgggtagtgt tgccgtgaca gttgtttgga aatggattta tgacccacta tcagggattc
    11881 taaactttgt ccttaagtcc agccacatca tcagccaaaa catttcttgg ttgggagata
    11941 aaaactgggc attgatggcg attatgatta ttctcttgac cacttcagtt ggtcagccca
    12001 tcatccttta tatcgctgcc atggggaata ttgacaattc actggttgaa gcggcgcgtg
    12061 ttgatggtgc aactgagttt caagtttttt ggaagattaa atggccaagc cttcttccaa
    12121 caactcttta tattgcaatc atcacaacaa ttaactcatt ccagtgtttc gccttgattc
    12181 agcttttgac atctggtggt ccaaactact caacaagtac cttgatgtac tacctttacg
    12241 aaaaagcctt ccaattgaca gaatacggct atgccaacac aattggtgtc ttcttggcag
    12301 tcatgattgc tatcgtaagc tttgttcaat ttaaagtact tggaaacgac gtagaatact
    12361 aaagaaagga gacagctatg caatctacag aaaaaaaacc attaacagcc tttactgtta
    12421 tttcaacaat cattttgctc ttgttgactg tgctgttcat ctttccattc tactggattt
    12481 tgacaggggc attcaaatca caacctgata caattgttat tcctcctcag tggttcccta
    12541 aaatgccaac catggaaaac ttccaacaac tcatggtgca gaaccctgcc ttgcaatgga
    12601 tgtggaactc agtatttatc tcattggtaa ccatgttctt agtttgtgca acctcatctc
    12661 tagcaggtta tgtattggct aaaaaacgtt tctatggtca acgcattcta tttgctatct
    12721 ttatcgctgc tatggcgctt ccaaaacaag ttgtccttgt accattggta cgtatcgtca
    12781 acttcatggg aatccacgat actctctggg cagttatctt gcctttgatt ggatggccat
    12841 tcggtgtctt cctcatgaaa caatttagtg aaaatattcc tacagagttg cttgaatcag
    12901 ctaaaatcga cggttgtggt gagattcgta ccttctggag tgtagccttc ccgattgtga
    12961 aaccagggtt tgcagccctt gcaatcttta ccttcatcaa tacttggaat gactacttca
    13021 tgcaattggt aatgttgact tcacgtaaca atttgaccat ctcacttggg gttgcgacca
    13081 tgcaggctga aatggcaacc aactatggtt tgattatggc aggagctgcc cttgctgctg
    13141 ttccaatcgt cacagtcttc cttgtcttcc aaaaatcctt cacacagggt attactatgg
    13201 gagcggtcaa aggataatac tctgcgaaaa tctcttcaaa ctacgtcagc ttcaccttgc
    13261 catacttaag tattgcctgc ggttagcttc ctagtttgtt cttcaatttt cattgagtat
    13321 aggaaaatca atctatcaag atacagaagt atattttata gatttagaga atatagaggt
    13381 tataagtgtc tacaaaatgg agggtatgca gttactttat gaagttttgt cagacactta
    13441 taaacttaag aatggtttta gttaactatc agaaacgaag gaaagagtat gatttttgac
    13501 gatttgaaaa acatcacctt ttacaaaggg attcatccca atttagacaa ggctatcgac
    13561 tacctctacc aacatcgtaa agattcattc gaattaggaa agtatgagat tgatggggat
    13621 aaagtctttc tagttgttca ggaaaatgtc ctcaatcaag ttgagaataa tcaatttgaa
    13681 caccataaga actatgcaga tttgcatttg ctgatagaag ggcatgaata ttcgagctac
    13741 ggttcacgta tcaaagacga ggcagtagca ttcgacgaag cgactgacat tggctttgtt
    13801 cattgtcatg aacactaccc cctcttgttg ggttatcaca attttgcgat tttcttccca
    13861 ggtgagccac atcagccaaa tggttatgca agcatggaag aaaaggttcg gaaatatctc
    13921 tttaaaattt tgattgatta aaaataggat gaattgtttt tttgtaaagc tttgacaata
    13981 ctctaccatg aaattgatct ttgtgaggta gggaaatgag aataaaatat ttaaaaattg
    14041 gtatcttctt gtcagtctgt gtatgctaca agagctagtt tcttggatgg acagggaatt
    14101 acagttgatg agatggcttg gataattagg ggcattgtga atgcattgat tggtagatac
    14161 ataaaattag gtacttatgc ggctaagtat ggtattagta tggcgcgttc tatcttaaat
    14221 agagcagctg caactgcggc agaaagagta ggattattga ctaagatttt tggatggatt
    14281 ttacgaatag ctgtgctcgc agctgatgta tatggtaatt ttgccaacaa tattgctgta
    14341 gcttgggatg cacatgataa aatccctaac aatggtcgta taaactttta aaatgcgaga
    14401 atgaaagcac tttgtatttt tttattgaat atgttagctt ggacagtgct tgcaatgata
    14461 attcgtggag ggctagatgg atttgatagg catacttgga gtaatatttt agctagtgcg
    14521 ttgtcctcgc tatacataca ttatatatcc atagatagaa aaagaaaaaa gtccaaaaga
    14581 aaaaagaaaa aatagatttg ttcatggtag ggacttatga aagctttact aacaaaaaag
    14641 aaaacagttt acaaagaaaa atgatggagg agtaaacatg gcacaaaaag gagtaagcct
    14701 tatcaaggca gcatttgata cagataactt tcttatgcgt tttagtgaga aagtcttgga
    14761 catcgtgaca gccaatcttc tttttgtcgt ctcttgtttg cccatcgtga cgattggagt
    14821 ggctaaaatc agcctctacg agaccatgtt tgagattaag aagagcagac gggtgcctgt
    14881 ttttaaaatc tatctaagat ctttcaagca aaatctgaaa ctaggtcttc agttaggtct
    14941 gcttgagttg ggcattgttt cattaagcct cctagatctt tatctctttt ggggtcaaac
    15001 agctctgccc tttcaattgc tgaaagctat ttgtctaggc attctgattt tccttacgat
    15061 tgtgatgttg gctagctatc caatcgcggc acgttatgat ttaacttgga aagaagtgtt
    15121 acaaaaaggg cttatcttgg caagttttaa ctttccttgg ttcttcctca tgttagccat
    15181 tcttgtcctc attgtgatgg ttctttatct gtctgccttc agtctacttt taggtggctc
    15241 agtcttcctg ctttttgggt ttggactatt ggtttttatc cagactggat tgatggagaa
    15301 aattttcgca aaataccaat aggagcctta tttctgaaac tactttcaaa ggctccaaac
    15361 gctattctat aagcgagaaa ctaaaatcta agtgtctata agatattgaa agccttttcg
    15421 gtaaagtgta tactaaagaa gtaaagaaaa atctgcttta gcagaaaata aaaataatag
    15481 gagaaaatct atgtcagatt tgaaaaaata cgaaggtgtc attccagcct tctacgcatg
    15541 ttatgatgat caaggagaag taagcccaga acgtacgcgt gccttggttc aatacttcat
    15601 tgataaaggt gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta tctaccaaag
    15661 cgttgaagat cgcaagttga ttttggaaga agtcatggcg gtagccaaag gtaaattgac
    15721 cattattgcc catgttgctt gcaataatac taaagatagt atggaacttg ctcgccatgc
    15781 tgaaagcttg ggagtagatg ctattgcaac gattccacca atttatttcc gcttgccaga
    15841 atactcagtt gccaaatact ggaacgatat cagttctgca gctccaaaca cagactacgt
    15901 gatttacaac attcctcaat tggcaggggt tgctttgact ccaagccttt acacagaaat
    15961 gttgaaaaat cctcgtgtta tcggtgtgaa gaactcttct atgccagttc aagatatcca
    16021 aacctttgtg agccttggtg gggaagacca tatcgtcttt aacggtccag atgaacagtt
    16081 cctaggtggt cgcctcatgg gtgccaaagc tggtatcggt ggtacttatg gtgctatgcc
    16141 agaactcttc ttgaaactca accaattgat tgcggataag gacctagaaa cagcgcgtga
    16201 attgcagtat gctatcaacg caatcattgg taaactcact tctgctcatg gaaatatgta
    16261 cggtgtcatt aaagaagtct tgaaaatcaa tgaaggcttg aatattggat ctgttcgttc
    16321 accattgaca ccagtgactg aagaagatcg tccagttgta gaagcggctg ctgccttgat
    16381 tcgtgaaacc aaggagcgct tcctctaatc taaaaggagg tatttatgac atactacgtt
    16441 gcaattgata tcggtggaac caacatcaag tatggtttgg ttgatcaaga ggggcaactt
    16501 cttgaatcgc atgaaatgcc aactgaggcg cataagggtg gacctcatat cttacaaaag
    16561 accaaagata tcgtagctag ttatttagaa aaaggcccag tagcaggtgt tgccatatct
    16621 tctgctggga tggtggatcc ggataagggt gagattttct atgctgggcc tcaaatccct
    16681 aactacgcag gcacccagtt caaaaaggaa atcgaagaaa gctttactat tccttgtgag
    16741 attgaaaatg atgtcaactg tgcaggtctt gctgaggcag tatctggttc aggcaaggga
    16801 gcaagtgtga cactttgctt gaccattgga accggtatcg gtggttgctt gattatggat
    16861 aggaaagtct tccatggttt tagcaattca gcctgtgaag tcgggtatat gcatatgcag
    16921 gatggagctt ttcaggatct cgcttctaca acagctttag tgaaatatgt agctgaagcc
    16981 catggagaag atgttgatca gtggaatggc cgacgtatct ttaaggaagc tactgaagga
    17041 aacaaaatct gcatggaagg tattgaccgt atggttgact atctaggaaa aggtctggca
    17101 aatatttgtt atgtggccaa tccagaagta gttattcttg gtggtggtat catggggcaa
    17161 gaggctatcc tcaaacctaa gatccgcaca gccttgaaag aggcattggt accaagttta
    17221 gcagaaaaaa cacgattaga atttgcccat caccaaaata cagcagggat gttgggtgca
    17281 tattatcatt ttaagacaaa acaatcctag tttggctcag ccaaactagg attttcttac
    17341 acgtttttgt ctacgatagc cgttgagttt tttattttcc cagtagctat taaagatttt
    17401 ttccttgctt tcgcgattga tttccaaaaa gtaggcataa atcaaatcga taaagaagag
    17461 cataggaagt tgagcggata ttcgttggat gtaggagggt tggctgtggg tggctacaag
    17521 aacagtctct gtataggtct ggctatcttt attgggaaca cttgtaaaga gtacagtctt
    17581 tgcccccatc tccttggcat ctaatagact atctaaaata gaaggagttg agcctgaaag
    17641 tgagaaaccc agtactagac aattttcatc catgatgctg gttgtccagg caaagccgtc
    17701 ttggtctgtc aaagcttcgc agaccacacc tagtcgcata aaacgtaatt tcatttcacg
    17761 ggcgacgagg ccagaactcc ctgttccaaa gaagtagata cgctcagcat cttcgattag
    17821 ctgggcaatt cgctctagtt ggatttcgtc aatcaagtct tgtgtttgtt ccctcatatt
    17881 gctataactt ctgaggactc gtttggtcag tggactatgc ttggagactt ggttggcttg
    17941 attttctgcc tgatgttggt attggaaaat aaattctcgg tagccagtaa agccacactt
    18001 tttagcaaag cgggtcaaag cagcttgaga aatatgtaat ttttgggtga cttgttgaga
    18061 agataaatca tctgtaatcg tttcagcttg caaaaaatag cgagcgattt cttgctctag
    18121 gtctgtcatt tcttcaaaat gtgaatcaat gatagttgcg atatctggtt tgtccatagg
    18181 gaaagctcct ttacatgggt catactggaa gactagatca gggaatagtc acacttcatt
    18241 ataacacata atataaggat agataaataa aaacgcattt ctgttttaaa aacgaaaaaa
    18301 tcgaaaaagc ttctttcttt tccataattt tctactcaaa ttgtggtaca attaagagta
    18361 agattttaag ttagaaatga gactgatttg tatgagaaaa tttaacagcc attcgattcc
    18421 gattcggctt aatttattgt tttcaatcgt cattttactc tttatgacca ttattggtcg
    18481 tttgttgtat atgcaggttt tgaacaagga tttttacgaa aaaaagctag cctcagctag
    18541 tcagaccaag attacaagca gttcagcccg tggggaaatt tatgatgcta gtggaaaacc
    18601 tttggtagaa aatacgttaa agcaggttgt ttcctttacg cgtagcaata aaatgacggc
    18661 tacagactta aaagaaacag ctaaaaagtt actgacttat gtgagcatca gttctccaaa
    18721 tttgacagaa cgccagctgg cggattacta tttggctgat cctgaaatct ataaaaaaac
    18781 agtggaagct ctcccaagtg agaaacgctt ggattcagat ggcaatcgtc tatccgaatc
    18841 agaactgtat aacaatgcgg tcgatagtgt ccaaacaagt caactaaact atacagagga
    18901 tgaaaagaaa gaaatctatc tttttagtca gttaaatgct gttggaaact ttgcgacagg
    18961 aaccattgct acagatcctc taaatgattc tcaggtggct gttattgcct ctatttcaaa
    19021 ggagatgcct ggcattagta tttctacttc ttgggataga aaggttttgg aaacttccct
    19081 ttcttctata gttgggagtg tatccagtga aaaagctggt ctcccagcgg aagaagcaga
    19141 agcctatctt aaaaaaggct attctctaaa tgatcgtgta ggaacctcct atttggaaaa
    19201 gcaatatgaa gagaccttac aaggaaaacg ctcggtaaaa gaaatccatc tggataaata
    19261 tggcaatatg gaaagcgtgg atacaattga ggaaggtagt aagggaaaca atatcaaact
    19321 gaccattgat ttggctttcc aagatagcgt ggatgcttta ctgaaaagtt atttcaattc
    19381 cgagctagaa aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg cccttaaccc
    19441 aaaaacaggt gcggttttgt ctatgtcagg gattaaacat gacttgaaaa cgggagagtt
    19501 gacgcctgat tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg ttgtcaaggc
    19561 ggcgaccatc agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga ccttgacaga
    19621 ccagtccatt gtcttccaag gttcagctcc catcaattct tggtatactc aggcttacgg
    19681 ttcattccct atcacagcgg tccaagctct ggagtattca tcaaatacct atatggtcca
    19741 aacagcctta ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg gcaccagcaa
    19801 tctagagtct gctatggaga aactgcgttc aacctttggc gaatatggct tgggtactgc
    19861 gacaggaatt gacctaccag atgaatctac tggatttgtt cccaaagagt atagctttgc
    19921 taattacatt actaatgcct ttgggcagtt tgataactat acgccgatgc agttggctca
    19981 gtatgtagca actattgcaa ataatggtgt tcgtgtggct cctcgtattg ttgaaggcat
    20041 ttatggtaat aatgataagg gaggactggg tgacttgatt cagcaactgc aaccgacaga
    20101 gatgaataag gtcaatatat ccgactccga tatgagcatc ttgcaccaag gtttttatca
    20161 ggttgcccat ggtactagtg aattgacaac tggacgtgcc ttttcaaatg gcgccttggt
    20221 atccattagc ggaaaaacag gtacagccga aagctatgtg gcagatggtc agcaagcaac
    20281 caataccaat gcggtggcct atgccccatc tgataatccc caaatcgctg ttgcagtggt
    20341 ctttcctcat aataccaatc taacaaatgg tgtaggacct tccattgcgc gtgacattat
    20401 caatctgtat caaaaatacc atccaatgaa ctagaaagga aattatgctt tatccaacac
    20461 ctattgccaa gttgattgac agttattcta agttaccagg tatcgggatt aagacggcta
    20521 cgcgtctggc cttttatacg attgggatgt ctgctgatga tgtcaatgaa tttgcaaaaa
    20581 atctcctttc tgctaagaga gaattgacat attgttctat ttgtggacgt ttgacagacg
    20641 acgatccttg ttctatctgt actgatccga ctcgtgacca gacaacaatt ttagttcttg
    20701 aggatagtag agatgtggca gccatggaaa atatccaaga ataccatgga ctctatcatg
    20761 tccttcatgg cctcatttct cctatgaatg gtatcagtcc ggacgatatc aatctcaaga
    20821 gccttatgac tcgtcttatg gatagtgaag tttcagaagt gattgtggcg actaatgcta
    20881 cagcggatgg tgaagcgact tccatgtatc tttcacgttt gctcaagccg gctggtatca
    20941 aggttacgcg tctagcacga ggtctcgctg tgggagcgga cattgagtat gcggacgaag
    21001 tgacactctt acgagcgatt gaaaatcgga cagagttgta agtgtaggca aatttacgaa
    21061 ctccattcat ttataaaaaa tcaaagaggc tgaaaatcgt tcctatcggc ctctttttgt
    21121 atagtgtgat gagtaggatc aggttcaagt tttaaaaaac caagcaaata tgatatacta
    21181 aagagcgagt attctagtag aattaggaca aataatatga aacaaacgat tattctttta
    21241 tatggtggac ggagtgcgga acgcgaagtc tctgtccttt cagctgagag tgtcatgcgt
    21301 gcggtcaatt acgaccgttt cacagtcaag actttcttta tcagtcagtc aggtgacttt
    21361 atcaaaacac aggaatttag tcatgctccg gggcaagaag accgtctcat gaccaatgaa
    21421 accattgatt gggataagaa agttgcacca agtgctatct acgaagaagg tgcagtggtc
    21481 tttccagtcc ttcacgggcc aatgggagaa gatggctctg ttcaaggatt cttggaagtt
    21541 ttgaaaatgc cttacgttgg ttgcaacatt ttgtcatcaa gtcttgccat ggataaaatc
    21601 acgactaagc gtgttctgga atctgctggt attgcccaag ttccttatgt ggctatcgtt
    21661 gaaggcgatg atgtgactgc taaaatcgct gaagtggaag aaaaattggc ttatccagtc
    21721 ttcactaagc cgtcaaacat ggggtctagt gtcggtattt ctaagtctga aaaccaagaa
    21781 gaactccgtc aagccttaaa acttgccttc cgatatgaca gccgtgtctt ggttgagcaa
    21841 ggagtgaatg cccgtgaaat tgaggttggc ctcttgggta actacgatgt caagagcacg
    21901 ctacctggag aagttgtcaa ggacgttgcc ttttatgact acgatgccaa gtatattgat
    21961 aacaagatta ctatggatat tcctgccaaa atcagtgatg atgtggtggc tgtcatgcgt
    22021 caaaatgcag aaacagcctt ccgtgccatt ggtggccttg gtctatctcg ttgcgatttc
    22081 ttctatacag ataagggaga gatttttctc aacgagctca ataccatgcc aggttttacc
    22141 cagtggtcta tgtacccact actttgggac aatatgggga tcagctaccc agaactaatc
    22201 gagcgtttgg ttgaccttgc caaggaaagt tttgacaagc gcgaagcgca tttgatataa
    22261 aatgaaagag agggtagaag ccagaaccat cactgcacgg tgactagagt tctcggactt
    22321 cagccctttt taaaggagta gaaatgaaat taacaatcca tgaaattgcc caagttgttg
    22381 gagccaaaaa tgatatcagt atctttgagg acacccagtt agaaaaagct gagtttgata
    22441 gtcgtttgat tggaactgga gatttatttg tgccacttaa aggtgcgcgt gatggccatg
    22501 actttattga aacagccttt gaaaatggtg cagcagtaac cttgtctgag aaagaggtct
    22561 caaatcatcc ttacattcta gtagatgatg ttttggcagc ctttcaatcc ctagcatcct
    22621 actatcttga aaaaacgact gttgatgtct ttgctgttac aggttcaaat ggcaagacaa
    22681 cgactaagga tatgttggcg catttactgt caacaagata caagacctac aaaacacaag
    22741 gcaattacaa taatgagatt ggccttcctt acacagttct tcatatgcct gaaggaacag
    22801 aaaagttggt tttggagatg ggacaggatc acttgggaga tattcatctc ttgtctgaat
    22861 tggctcgtcc aaaaacagcc atcgtgacct tggttggaga agctcatttg gcctttttca
    22921 aagaccgttc tgagattgct aaaggaaaaa tgcaaattgc agacggaatg gcttcaggtt
    22981 ccttgctttt agcgccggct gaccctatcg tagaggacta tttgccaact gataaaaagg
    23041 tggttcgttt tggtcaagga gcagagctgg gaattaccga cttggttgag cgcaaagata
    23101 gtctgacctt caaggtcaat ttcttagagc aagcccttga tttgccagta actggcaagt
    23161 acaatgcgac aaatgctatg attgcatcct atgttgcctt gcaagaagga gtttcagagg
    23221 agcaaattcg tttggccttc caacatcttg aattgacgcg taaccgtacc gagtggaaga
    23281 aagcagccaa tggagcagat atcctgtcag atgtttataa tgccaatcca actgctatga
    23341 aactgatttt agagactttc tctgccattc cagccaatga aggtggcaag aaaattgcag
    23401 tgttggcgga tatgaaggag cttggtgacc agtctgttca acttcataat cagatgattt
    23461 tgagcctctc cccagatgtg cttgatatcg ttattttcta tggagaagat attgctcagt
    23521 tggctcaatt ggccagtcaa atgtttccaa tcggccacgt ttactacttc aagaaaacag
    23581 aagaccagga tcaatttgaa gacctagtca agcaggttaa ggaaagcctt ggagctcatg
    23641 accaaatcct gctcaaaggc tctaactcta tgaatctagc caagttggta gaaagtttag
    23701 aaaatgaaga caagtgattt tgtcaagtat ttgcaaagaa tgattgccat tacagatact
    23761 ggcttaacct ttacaaaaga tccgtttgac cgtgagcgct acgaagactt gcgaagtctg
    23821 ttatctgaaa tgttgaatca ggtatcagac ctggatgcag aagaagtagc agaagtcttg
    23881 aaaccaactt cagcttatgc gactccctta atggacgtcc gtgcttggat tgttgaggat
    23941 gagaagattt gtctggttag gggacaagga gaggatagtt gggctttgcc aggtggcttt
    24001 ggtgaagtcg gctattctcc aactgaaaat attctcaagg aaattgaaga agaaaccggt
    24061 tttaaagcca aagttgaaag actgctagct gtttttgata ccaatcgttt ccaactacag
    24121 agtaaacaat atgcaaagtt tgtttttgaa tgtaagtttc tcgatggaca attccaagaa
    24181 aatcaagaaa ttgcagatct tcaatttttt gccattgacc aactgccgaa cttatctgaa
    24241 aaacgcatta ccaaggagca aatagagctt ctttggcagg tttatcaagg tcataggggg
    24301 caatatcttg actaagaaga tgattatcgt atttttaaat ccatttttaa caactagcat
    24361 ggtataataa tatgcaggaa aattttgaat tatgaggaag actagatgaa tttatgggat
    24421 attttcttta cgactcaggc aaccgagccg cccaaatttg accttttttg gtatgttagc
    24481 ctatttacgc tcttagcctt aaccttttat acagcccatc gctatcgtga aaagaaggtt
    24541 taccaacgat ttttccaaat cttgcagact gttcagttaa tccttcttta tggttggtac
    24601 tgggtcaatc atatgccact gtcagaaagc ctaccctttt accattgccg tatggctatg
    24661 tttgtggtac tcttgcttcc tggtcagtcc aaatataaac aatactttgc attattggga
    24721 acatttggga cattagcagc ctttgtttat ccagtgccag atgcttaccc ttttccacat
    24781 atcaccattc tatcctttat ctttggtcat ttagcactct tggggaactc tctagtttat
    24841 ctattgagac agtataatgc gcgattgctg gatgtgaagg gaatttttct catgaccttt
    24901 gccctaaatg ccttgatttt tgtggtcaat ttggtgacag gtggcgatta cggatttttg
    24961 acaaaaccgc cattggttgg ggatcacggt ctagtagcta attatttact tgtttcaatt
    25021 gtgctggtag ctactatcag tttgactaag aaaatcttag aattcttttt agctcaagaa
    25081 gcagaaaaaa tgattgcaaa ggaagcttaa cacagagctt tcttttttgc tcttagagag
    25141 tttttacaag cagcttataa aataagaatt tctgaataga caaactcaaa aaatggctgg
    25201 gaaatttagg aaaaaagcaa gcacgattaa attttttgtg ttataatatt ttgtgaatag
    25261 ctatgcctat gtttagctat ggaataatac gaagtgcgaa acttggaaga tagagaggaa
    25321 gcgatgtaat ggctagagaa ggctttttta caggtctaga tattggaaca agctctgtca
    25381 aggtgcttgt ggccgagcag agaaatggtg aattaaatgt aattggcgtg agtaatgcca
    25441 aaagtaaagg tgtaaaggat ggaattattg ttgatattga tgcagcagca actgctatca
    25501 agtcagccat ttcccaagcg gaagaaaagg caggcatttc gattaaatca gtgaatgtcg
    25561 gcttgcctgg taatcttttg caggtagaac caactcaggg gatgattcca gtaacatctg
    25621 atactaagga aattacggat caagatgttg aaaatgttgt caaatcagct ttgacaaaga
    25681 gtatgacacc tgaccgtgaa gtcattacct ttattcctga agaatttatt gtggatggtt
    25741 tccaagggat tcgtgaccca cgtggtatga tgggggttcg ccttgaaatg cgtggtttgc
    25801 tttatacagg acctcgtact atcttgcaca atttgcgtaa gacggttgag cgtgcaggtg
    25861 ttcaggttga aaatgttatc atttcaccac tagcaatggt tcagtctgtt ttgaacgaag
    25921 gggaacgtga atttggtgct acagtgattg atatgggggc aggtcaaacg actgtcgcta
    25981 caatccgtaa tcaagaactc cagttcacac atattctcca agaaggtgga gattatgtaa
    26041 ctaaagatat ctccaaggtt ttgaaaacct ctcgcaaatt agcggaaggc ttgaaactga
    26101 attacgggga agcctatccg cctcttgcaa gcaaagaaac cttccaagta gaggttattg
    26161 gagaagtgga agcagtcgaa gtgacggaag cctacttgtc agaaattatt tctgcacgaa
    26221 tcaagcacat ccttgaacaa atcaagcaag aattagatag aaggcgtcta ttggacctcc
    26281 ctggtggtat tgtcttaatc ggtgggaatg ccattttacc aggtatggtt gagcttgctc
    26341 aggaagtctt tggcgtccgt gtcaagcttt atgttccaaa tcaagttggt atccgtaatc
    26401 cagcctttgc gcatgtgatt agtttatcag aatttgcggg tcaattaaca gaagttaatc
    26461 ttttggctca gggagcgata aaaggtgaga atgacttaag tcatcagcca attagttttg
    26521 gtgggatgct gcaaaaaaca gctcagtttg tacaatcaac gcctgttcaa ccagctcctg
    26581 ctccagaagt agagccggtg gcgcctacag aaccaatggc ggatttccaa caagcttcac
    26641 aaaataaacc gaaattagca gatcgtttcc gtggcttgat cggaagcatg tttgacgaat
    26701 aaagaggaaa aataaattat gacattttca tttgatacag ctgctgctca aggggcagtg
    26761 attaaagtaa ttggtgtcgg tggaggtggt ggcaatgcca tcaaccgtat ggtcgacgaa
    26821 ggtgttacag gcgtagaatt tatcgcagca aacacagatg tacaagcatt gagtagtaca
    26881 aaagctgaga ctgttattca gttgggacct aaattgactc gtggtttggg tgcaggaggt
    26941 caacctgagg ttggtcgtaa agccgctgaa gaaagcgaag aaacactgac ggaagctatt
    27001 agtggtgccg atatggtctt catcactgct ggtatgggag gaggctctgg aactggagct
    27061 gctcctgtta ttgctcgtat cgccaaagat ttaggtgcgc ttacagttgg tgttgtaaca
    27121 cgtccctttg gttttgaagg aagtaagcgt ggacaatttg ctgtagaagg aatcaatcaa
    27181 cttcgtgagc atgtagacac tctattgatt atctcaaaca acaatttgct tgaaattgtt
    27241 gataagaaaa caccgctttt ggaggctctt agcgaagcgg ataacgttct tcgtcaaggt
    27301 gttcaaggga ttaccgattt gattaccaat ccaggattga ttaaccttga ctttgccgat
    27361 gtgaaaacgg taatggcaaa caaagggaat gctcttatgg gtattggtat cggtagtgga
    27421 gaagaacgtg tggtagaagc ggcacgtaag gcaatctatt caccacttct tgaaacaact
    27481 attgacggtg ctgaggatgt tatcgtcaac gttactggtg gtcttgactt aaccttgatt
    27541 gaggcagaag aggcttcaca aattgtgaac caggcagcag gtcaaggagt gaacatctgg
    27601 ctcggtactt caattgatga aagtatgcgt gatgaaattc gtgtaacagt tgtcgcaacg
    27661 ggtgttcgtc aagaccgcgt agaaaaggtt gtggctccac aagctagaac tgctactaac
    27721 taccgtgaga cagtgaaacc agctcattca catggctttg atcgtcattt tgatatggca
    27781 gaaacagttg aattgccaaa acaaaatcca cgtcgtttgg aaccaactca ggcatctgct
    27841 tttggtgatt gggatcttcg ccgtgaatcg attgttcgta caacagattc agtcgtttct
    27901 ccagtcgagc gctttgaagc cccaatttca caagatgaag atgaattgga tacacctcca
    27961 tttttcaaaa atcgttaagt aaatgaatgt aaaagaaaat acagaacttg tttttcgaga
    28021 agttgcagag gctagtctga gtgctcatcg agagagtggt tcggtctctg tcattgcagt
    28081 taccaagtat gtagatgtac cgacagcgga agccttgctt ccgctaggtg ttcatcatat
    28141 cggtgaaaat cgtgtagata agtttctgga aaaatatgaa gctttaaaag atcgagatgt
    28201 gacttggcat ttgattggta ccttgcaaag acgtaaggtg aaagatatca ttcaatacgt
    28261 tgattatttc catgcattgg actcagtaaa gctagcaggg gaaattcaaa aaagaagtga
    28321 ccgagtcatc aagtgtttcc ttcaagtaaa tatttctaaa gaagaaagca aacacggttt
    28381 ttcgagagag gaactgctgg aaatcttgcc agagttagcc agactagata agattgaata
    28441 tgttggttta atgacgatgg caccttttga ggctagcagt gagcagttga aagagatttt
    28501 caaggcggcc caagatttac aaagagaaat tcaagagaaa caaattccaa atatgcctat
    28561 gaccgagtta agtatgggaa tgagtcgtga ttataaagaa gcgattcaat tcggttccac
    28621 ttttgttcgt ataggtacat cattttttaa gtaggagaga accatgtctt taaaagatag
    28681 attcgataga tttatagatt attttacgga ggatgaggat tcaagtctcc cttatgaaaa
    28741 aagagatgag cctgtgttta ctccagtaaa ttcttcacag gaaccggctc tcccaatgaa
    28801 tcaaccttca cagtcggctg gtacaaaaga gaacaatatc accagacttc atgcaagaca
    28861 acaggaattg gcaaatcaga gtcagcgtgc aacggataag gtcattatag atgttcgtta
    28921 tcctagaaaa tatgaggatg caacagaaat tgttgattta ttggcaggaa acgaaagtat
    28981 cttgattgat tttcagtata tgacagaggt gcaggctcgt cgttgtttgg actatttgga
    29041 tggagcttgt catgttttag ctggaaattt gaaaaaggta gcttctacca tgtatttgtt
    29101 gacaccagtg aatgttattg taaatgttga agatatccgt ttaccagatg aagatcaaca
    29161 gggtgagttc ggttttgata tgaagcgaaa tagagtacga taatgatttt tttaattcgt
    29221 atgatttata atgcagtgga tatttactcc ctgattttgg tagccttcgc tgtcatgtct
    29281 tggtttccag gtgcctacga atccagttta ggtcgttgga ttgtagcgtt ggtgaaacca
    29341 gtgcttgctc ccttgcaacg cctgccttta cagatagcgg gtcttgattt atctgtttgg
    29401 gtcgcgattg ttttggttcg atttttagga gaaaacctag tgcgttttct ggcgatgata
    29461 ggatgaataa agggatttat cagcatttct ccatagaaga tcgtccattt cttgacaagg
    29521 gaatggaatg gataaagaag gtagaagata gctatgctcc ttttttaact ccttttatca
    29581 atcctcatca ggagaagcta ttaaagattt tggccaaaac ctatggtctt gcttgtagca
    29641 gtagtgggga attcgtctcg agtgagtatg ttcgagtttt attataccca gattatttcc
    29701 aaccagagtt ttcagatttt gaaatatctc tccaggaaat tgtgtattcc aataaatttg
    29761 aacatttaac gcatgctaag attttaggga cagtcatcaa tcaattaggg attgaacgga
    29821 aactttttgg agatatccta gtagatgaag aacgggcgca gattatgatt aatcagcagt
    29881 ttcttcttct ctttcaagat ggactaaaga aaattggtcg tatacctgtt tcgctggagg
    29941 aacgtccttt caccgagaaa atagataagc tagaacagta tcgagaactg gatttatctg
    30001 tgtttagttt tcgattagat gttcttttat caaatgtttt gaaactatct aggaatcaag
    30061 caaaccagtt gattgaaaag aaacttgtcc aagtaaatta tcatgtggta gacaaatcag
    30121 attacactgt tcaagttgga gacttgatta gtgtgagaaa atttggccgc ttgagattac
    30181 ttcaagataa gggacaaacg aaaaaagaga agaaaaaaat aaccgtccag ttattattaa
    30241 gtaagtgagg aatagaatgc caattacatc attagaaata aaggacaaga cttttggaac
    30301 tcgattcaga ggttttgatc cagaagaagt cgatgaattt ttagatattg tggttcgtga
    30361 ttacgaagat cttgtgcgtg cgaatcatga taaaaatttg cgtattaaga gtttagaaga
    30421 gcgtttgtct tactttgatg aaataaaaga ttcattgagc cagtctgtat tgattgctca
    30481 ggatacagct gagagagtga aacaggcggc gcatgaacgt tcaaacaata tcattcatca
    30541 agcagagcaa gatgcgcaac gcttgttgga agaagctaaa tataaggcaa acgagattct
    30601 tcgtcaagca actgataatg ctaagaaagt cgctgttgaa acagaagaat tgaagaacaa
    30661 gagccgtgtc ttccaccaac gtctcaaatc tacaattgag agtcagttgg ctattgttga
    30721 atcttcagat tgggaagata ttctccgtcc aacagctact tatcttcaaa ccagtgatga
    30781 agcctttaaa gaagtggtta gcgaagtact tggagaaccg attccagctc caattgaaga
    30841 agaaccaatt gatatgacac gtcagttctc tcaagcagaa atggaagaat tacaagctcg
    30901 tattgaggta gccgataaag aattgtctga atttgaagct cagattaaac aggaagtgga
    30961 aactccaact cctgtagtga gtcctcaagt tgaagaagag cctctgctca tccagttggc
    31021 ccaatgtatg aagaaccaga agtagctcca gtgcatccga caggtccaac accagctaca
    31081 gaaactgttg attcagcacc gggatttgaa gcaccgcaag aatctgttac aattttataa
    31141 gaaatattct gagaacaata tcttatcctt atattcccag cgagcaggag atggtgtgag
    31201 tcctgcattc cctatcgata agattatcct ctcaaaaact caagtctgaa gctagtaaga
    31261 tttgacgttc cccacgttac gggataagag ggagaaagac taaaactttt tccgaataaa
    31321 ggtggtacca cgattttcgt cctttttgga agtcgtggtt tttaatttgt tattatttat
    31381 aaaggagata ccatgaaact caaagacacc cttaatcttg ggaaaactga attcccaatg
    31441 cgtgcaggcc ttcctaccaa agagccagtt tggcaaaagg aatgggaaga tgcaaaactt
    31501 tatcaacgtc gtcaagaatt gaaccaagga aaacctcatt tcaccttgca tgatggccct
    31561 ccatacgcta acggaaatat ccacgttgga catgctatga acaagatttc aaaagatatc
    31621 attgttcgtt ctaagtctat gtcaggattt tacgcaccat ttattcctgg ttgggatact
    31681 catggtctgc caatcgagca agtattgtca aaacaaggtg tcaaacgtaa agaaatggac
    31741 ttggttgagt acttgaaact ttgccgtgag tacgctcttt ctcaagtaga taaacaacgt
    31801 gaagatttta aacgtttggg tgtttctggt gactgggaaa atccatatgt gaccttgact
    31861 cctgactatg aagcagctca aattcgtgta tttggtgaga tggctaataa gggttatatc
    31921 taccgtggtg ccaagccagt ttactggtca tggtcatctg agtcagccct tgctgaagca
    31981 gagattgaat accatgattt ggtttcaact tccctttact atgccaacaa ggtaaaagat
    32041 ggcaaaggag ttctagatac agatacttat atcgttgtct ggacaacgac tccatttacc
    32101 atcacagctt ctcgtggttt gacggttggt gcagatattg attacgtttt ggttcaacct
    32161 gctggtgaag ctcgtaagtt tgtcgttgct gctgaattat tgactagctt gtctgagaaa
    32221 tttggctggg ctgatgttca agttttggaa acttaccgtg gccaagaact caaccacatc
    32281 gtaacagaac acccatggga tacagctgta gaagagttgg taattcttgg tgaccacgtt
    32341 acgactgact ctggtacagg tattgtccat acagcccctg gttttggtga ggacgattac
    32401 aatgttggta ttgctaataa tcttgaagtc gcagtgactg ttgatgaacg tggtatcatg
    32461 atgaagaatg ctggtcctga atttgaaggt caattctatg aaaaggtagt tccaactgtt
    32521 attgaaaaac ttggtaacct ccttcttgcc caagaagaaa tctctcactc atatccattt
    32581 gactggcgta ctaagaaacc aatcatctgg cgtgcagttc cacaatggtt tgcctcagtt
    32641 tctaaattcc gtcaagaaat cttggacgaa attgaaaaag tgaaattcca ctcagaatgg
    32701 ggtaaagtcc gtctttacaa tatgatccgt gaccgtggtg actgggttat ctctcgtcaa
    32761 cgtgcttggg gtgttccact tcctatcttc tacgctgaag atggtacagc tatcatggta
    32821 gctgaaacta ttgaacacgt agctcaactt tttgaggaac atggttcaag catttggtgg
    32881 gaacgtgatg ccaaagacct cttgccagaa ggatttactc atccaggttc accaaacggc
    32941 gagttcaaaa aagaaactga tatcatggac gtttggtttg actcaggttc atcatggaat
    33001 ggagtggtgg taaaccgtcc tgaattgact tatccagctg acctttacct tgaaggttct
    33061 gaccaatacc gtggttggtt caactcatca ctcattacat ctgttgccaa ccatggcgta
    33121 gcaccttaca aacaaatctt gtcacaaggt tttacccttg atggtaaagg tgagaagatg
    33181 tctaaatcac ttggaaatac cattgctcca agtgatgttg aaaaacaatt tggtgcagaa
    33241 atcttgcgtc tctgggtaac aagtgttgac tcaagcaatg acgtgcgtat ctctatggat
    33301 attttgagcc aagtttctga aacttaccgt aagattcgta acactcttcg tttcttgatt
    33361 gccaatacat ctgactttaa cccagctcaa gatgtagtcg cttacgatga acttcgttca
    33421 gttgataagt acatgactat tcgctttaac cagcttgtca agaccattcg tgatgcctat
    33481 gcggactttg aattcttgac aatctacaag gccttggtga actttatcaa cgttgacttg
    33541 tcagccttct accttgattt tgccaaagat gttgtttaca ttgaaggtgc caaatcattg
    33601 gaacgccgtc aaatgcagac tgttttctat gacattcttg tcaaaatcac caaactcttg
    33661 acaccaatcc ttcctcacac tgcggaagaa atctggtcat atcttgagtt tgaagctgaa
    33721 gacttcgttc aattgtcaga attgccagaa gctcaaactt ttgctaatca agaagaagtc
    33781 ttggatacat gggcagcctt catggacttc cgtggacaag ctcaaaaagc cttggaagaa
    33841 gctcgtaatg caaaagttat cgggaaatcg cttgaagcac acttgacagt ttatccaaat
    33901 gaagttgtga aaactctact cgaagcagta aacagcaatg tggctcaact tttgatcgtg
    33961 tcagacttga ccatcgcaga agggccagct ccagaagctg ctgttagctt cgaagatgta
    34021 gccttcacag ttgaacgcgc tgcaggtcaa gtatgtgacc gttgccgtcg tatcgaccca
    34081 acaacagcag aacgcagcta ccaggcagtc atctgtgacc actgtgcaag catcgtagaa
    34141 gaaaactttg cggaagcagt cgcagaagga tttgaagaga aataaggttg aaaagtctag
    34201 gcaaaattca atttgagaag aaaagacaac taattttata gtctattaaa cgcattgtat
    34261 cacgtttttg aatacctgat atgatgcgtt ttttatttat tttaaaaatt tgcgaggtat
    34321 gactttttat actcaacaag aatcaaagag aaacttagca agctaacagt agtaagataa
    34381 aataggaatt tgatattagg g
//
LOCUS       DAVLGK010000022        31583 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLGK010000022 DAVLGK010000000
VERSION     DAVLGK010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.022"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            700..1504
                     /locus_tag="VXE01_001146"
                     /pseudo
     CDS             700..1504
                     /locus_tag="VXE01_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; incomplete;
                     partial in the middle of a contig; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1657..1911
                     /gene="blpM"
                     /locus_tag="VXE01_001147"
     CDS             1657..1911
                     /gene="blpM"
                     /locus_tag="VXE01_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV0750055.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATSGF"
     gene            1927..2130
                     /gene="blpN"
                     /locus_tag="VXE01_001148"
     CDS             1927..2130
                     /gene="blpN"
                     /locus_tag="VXE01_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV0750056.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            2374..2607
                     /locus_tag="VXE01_001149"
     CDS             2374..2607
                     /locus_tag="VXE01_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family peptide pheromone/bacteriocin"
                     /protein_id="HEV0750057.1"
                     /translation="MDTKMMSQFSVMDNEMLVRTEDGDVSDIYRGYANQRSPFASYPS
                     ILKNSGPFPVSGYCLRGYHDRGYIGAGFHLCGI"
     gene            2639..3328
                     /locus_tag="VXE01_001150"
     CDS             2639..3328
                     /locus_tag="VXE01_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0750058.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFSGVMIWILVKTGHGYLFRIPRKKWLWYSILTVLVVVLHISFNVQTAKH
                     VQSTAEGWNVLIGYSGTNFAELGIYVTLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFLSLPSLLDIFVFATFGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3370..3603
                     /locus_tag="VXE01_001151"
     CDS             3370..3603
                     /locus_tag="VXE01_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750059.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            3754..4365
                     /locus_tag="VXE01_001152"
     CDS             3754..4365
                     /locus_tag="VXE01_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0750060.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            4526..5320
                     /locus_tag="VXE01_001153"
     CDS             4526..5320
                     /locus_tag="VXE01_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV0750061.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5317..5952
                     /gene="trmB"
                     /locus_tag="VXE01_001154"
     CDS             5317..5952
                     /gene="trmB"
                     /locus_tag="VXE01_001154"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV0750062.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6078..6557
                     /gene="rimP"
                     /locus_tag="VXE01_001155"
     CDS             6078..6557
                     /gene="rimP"
                     /locus_tag="VXE01_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV0750063.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTHKKTVRIPYSLVSKARLAVKL"
     gene            6601..7737
                     /gene="nusA"
                     /locus_tag="VXE01_001156"
     CDS             6601..7737
                     /gene="nusA"
                     /locus_tag="VXE01_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV0750064.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VTIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7759..8052
                     /locus_tag="VXE01_001157"
     CDS             7759..8052
                     /locus_tag="VXE01_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV0750065.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8045..8344
                     /locus_tag="VXE01_001158"
     CDS             8045..8344
                     /locus_tag="VXE01_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV0750066.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLAKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8361..11153
                     /gene="infB"
                     /locus_tag="VXE01_001159"
     CDS             8361..11153
                     /gene="infB"
                     /locus_tag="VXE01_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV0750067.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMMDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11404..11754
                     /gene="rbfA"
                     /locus_tag="VXE01_001160"
     CDS             11404..11754
                     /gene="rbfA"
                     /locus_tag="VXE01_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV0750068.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            12033..12812
                     /locus_tag="VXE01_001161"
     CDS             12033..12812
                     /locus_tag="VXE01_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750069.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDSSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWVSREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            12814..12996
                     /locus_tag="VXE01_001162"
     CDS             12814..12996
                     /locus_tag="VXE01_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750070.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(13336..13413)
                     /locus_tag="VXE01_001163"
                     /pseudo
     CDS             complement(13336..13413)
                     /locus_tag="VXE01_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            13444..13677
                     /locus_tag="VXE01_001164"
     CDS             13444..13677
                     /locus_tag="VXE01_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV0750071.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            13677..15011
                     /locus_tag="VXE01_001165"
     CDS             13677..15011
                     /locus_tag="VXE01_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV0750072.1"
                     /translation="MTDERIHVLRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            15021..15275
                     /locus_tag="VXE01_001166"
     CDS             15021..15275
                     /locus_tag="VXE01_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV0750073.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            15371..15766
                     /locus_tag="VXE01_001167"
     CDS             15371..15766
                     /locus_tag="VXE01_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0750074.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            16179..16628
                     /locus_tag="VXE01_001168"
     CDS             16179..16628
                     /locus_tag="VXE01_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HEV0750075.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQISILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPEFLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            16615..17172
                     /locus_tag="VXE01_001169"
     CDS             16615..17172
                     /locus_tag="VXE01_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0750076.1"
                     /translation="MARTELSDKIETERLVLRVRTVADAEDIHAYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIAGSVDFNHRYGDDVLELGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEE"
     gene            17174..18136
                     /locus_tag="VXE01_001170"
     CDS             17174..18136
                     /locus_tag="VXE01_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV0750077.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDINFTYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            18148..20799
                     /locus_tag="VXE01_001171"
     CDS             18148..20799
                     /locus_tag="VXE01_001171"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV0750078.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKNLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            20869..21624
                     /locus_tag="VXE01_001172"
     CDS             20869..21624
                     /locus_tag="VXE01_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV0750079.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            21907..22710
                     /locus_tag="VXE01_001173"
     CDS             21907..22710
                     /locus_tag="VXE01_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV0750080.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(22826..24085)
                     /locus_tag="VXE01_001174"
                     /pseudo
     CDS             complement(22826..24085)
                     /locus_tag="VXE01_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            24332..27010
                     /locus_tag="VXE01_001175"
     CDS             24332..27010
                     /locus_tag="VXE01_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0750081.1"
                     /translation="MAVFVSLDGIVVEVLDVFSSFNGDSEFFLCKRLKDKSQFVMERS
                     QFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKSFINDQGKIQYFPSYDCGWKQLL
                     PEKRSFQTLTDSVLKSHFRGETAIGIFPMHLDDSCHFLVLDFDEGDWKEAGLTIRRIA
                     RERQMEAHLEISRSGHGLHIWFFFEEAIPSREARLFGKKLIELAMQESMQLSFDSFDR
                     MFPNQDVLPKGGFGNLIALPFQGEAYHQVRTVFVDEQFQPYEDQWRYLQEIQRVSTAK
                     VALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFFLKNMASFSNPEFYLKQAM
                     RQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSVEDRRKVQRSISVEFKGEL
                     TFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKTKTIILVHNKQLLDQWLDR
                     LNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSL
                     LDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILH
                     TADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWIATDSARNQLILKDILAQV
                     AEGRNILVLVNRIQQIDVFEKLLKEKEVDDCYIISGKTKVRERTSLLETLEQLDKGFV
                     LLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIH
                     VPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKVLREDLAGERQECLLILPY
                     VHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKIKVSFTQSKIVTPILLVNK
                     TIVWYGAMPLLGKVDEMTILRLESASIASELVAGLR"
     gene            27310..28149
                     /locus_tag="VXE01_001176"
     CDS             27310..28149
                     /locus_tag="VXE01_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0750082.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKKALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            28167..30005
                     /locus_tag="VXE01_001177"
     CDS             28167..30005
                     /locus_tag="VXE01_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0750083.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            30018..31433
                     /locus_tag="VXE01_001178"
     CDS             30018..31433
                     /locus_tag="VXE01_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0750084.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSAIPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
BASE COUNT         9796 a         5396 c         6863 g         9528 t
ORIGIN      
        1 gggatgggaa gtactaccac agatttatta ttaattttat cagtattgtt tgaaatccaa
       61 aaaaagtatg ttaagctata tttatttggt tctttagttt gattgttgtt gagtataact
      121 atttttgtat agatgaaaat cttgttattg ttcaagatgt tttgatgacc attcatgatt
      181 tgagtaatcc aaggtcaaaa tgagtgctat actagcagtg taaagattct tgttcaacta
      241 agataaatca cacatttagg aggaaatttt atgaagaaaa aaatacttat cattttcatc
      301 ttgtatctaa tcatgtccat ctttctttat ccgcttaggg aaagtatttg gtatcagcta
      361 ttttatacca tagcctatgt gattgcagtt atgatctatt ttgctttaac taaaaagaaa
      421 ggagcaaaga aatgaaaact tttcttgcta aaaaacggaa catcttcctt tcgtttgggg
      481 gttgaagtat tataaaaagt agaagttaat gaagtataaa agggtaagtg tttttgcaat
      541 acttaccctt ttataataga ttccctgcga aacaaaatat ggtatagtat agtagattga
      601 aactagaata gtacgcctct acttctaaaa cattgttaga aatcgatttg actgtcctga
      661 ttgatttatc ctgttcttat ttcattttac tatagttcta tgaattatga aggaagtaaa
      721 caactaactg atgcacgatt taaatgtctt gttggtgttc aacgcacgac ttttgaagag
      781 atgttagctg tattaaaaac agcttatcaa cttaaacacg caaaaggtgg acgaaaacct
      841 aaattaagcc tagaagacct tcttatggcc actcttcact atgtgcgaga atatcgaact
      901 tatgaagaaa ttgcggctga ttttggtatc cacgaaagca acttactccg tcggagccaa
      961 tgggttgaag taactcttgt tcaaagtggt gttacgattt caagaactcc tctcagctct
     1021 gaggacacgg taatgattat tgatgcgacg gaagtataaa tcaatcgccc taaaaaaaga
     1081 attagcgaat gattctggta aaaagaaatg ccacgctatg aaggctcaag cgattgtcac
     1141 aagtcaaggg agaattgttt ctttggatat cactgtgaac tattgtcatg atatgaagtt
     1201 gttcaaaatg agtcgcagaa atatcggaca agctggtaaa atcttgactg acagtgatta
     1261 tcaagggccc atgaagatat atcctcaagc acaaattcca cgtaaatcca gcaaactcaa
     1321 gccactaaca gctgaagata aagcctataa ccatgcgcta tctaaggaga gaagcaaggt
     1381 tgagaacatc tttgccaaag taaaaacgtt taaaatgttt tcaacaacct atcgaaatca
     1441 tcgtaaacgc ttcggattac gaatgaattt gattgctggt attatcaatc atgaactagg
     1501 attttggttt cgcaggaagt ctaatgtaat ttttgcaatt caagacgttt cgatgactat
     1561 tcaagatctg gatgaaaaat tttaaaaaac gatgatatac taaacttgtc aaagttacaa
     1621 caagacaaaa attaaaaata aaaaagagta tttgtcatgg atacaaaaat tatggaacaa
     1681 tttcatgaaa tggatataac tatgttatct agtattgaag gaggcaagaa taattggcaa
     1741 actaatgtct tagaaggtgg tggtgctgct tttggtggct gggggttagg gacagctatt
     1801 tgtgctgcga gtggtgttgg agcgccattt atgggagcat gtggatacat aggagctaaa
     1861 tttggtgtgg ctctttgggc aggagtaaca ggggcaacga gtggatttta acaaaaggag
     1921 acttgtatga atacttattg taatataaat gaaacaatgc tgagtgaggt ttatggaggt
     1981 aattccggag gagcagctgt agttgctgct ttaggttgtg cagcgggtgg agtgaaatat
     2041 gggagacttc taggaccatg gggcgctgca ataggaggaa ttggaggagc agtggtttgt
     2101 ggatatttag cctataccgc tacatcataa aaatgaaagc taaattttat gaaggctata
     2161 ttctttatta ttctcttcgc ttttcaaacc tatcttattt atctatccat aagtatctcc
     2221 gataaaaaac aaaagactat tgaattaaca tcattgaatt gttttgtcat attatttcta
     2281 atctatgata aattaatttt tctctttatt gcttatgttt ttttgataat ttttatatta
     2341 aacttgttcc gtaactgaaa agtgatatac tatatggata caaaaatgat gtcacaattt
     2401 tctgttatgg ataatgaaat gcttgttcgt acagaggatg gggatgtctc tgatatttat
     2461 agagggtacg ctaatcagag aagtccattc gcttcttacc cttctatatt aaaaaattca
     2521 ggtccttttc cagtaagtgg gtactgcctg cgtggttatc atgaccgtgg ttatatagga
     2581 gcaggttttc atttatgtgg aatataggct gaaatacaag aaatgaggga ggatttctat
     2641 gaaaaagtat caacttctat tcaaaataag tgcagtcttc tcttacttat ttttcgtatt
     2701 tggtctttct cagctgacgc ttatcgtcca aaattattgg caattttctt cccagattgg
     2761 caatttcgtc tggattcaaa atatcttgag tttactattt agcggagtca tgatttggat
     2821 tctggttaag acaggccatg gctatctctt tcgcattcca agaaaaaaat ggctttggta
     2881 ttctattttg acagtattag tggtagtgct ccatatctct tttaacgttc agacagctaa
     2941 acatgttcag tcaactgctg agggttggaa cgtattgatt ggttatagtg ggaccaactt
     3001 tgctgagcta ggtatctatg taaccctgtt tttcctgact ccactaatgg aagagttgat
     3061 ttatagggga ttacttcaac acgccttctt taagcattcg cgatttggcc ttgatttgct
     3121 tcttccttcc attttgtttg ctcttcctca ttttttgagt ctgcctagtc tgttagatat
     3181 cttcgtcttt gcaacatttg gaatcatctt tgccggtttg acccgctata ccaagagtat
     3241 ttatccatcc tatgcggtgc atgtgatcaa taatattgta gcgaccttcc cgtttttgct
     3301 cacttttcta catagggtct tggggtaaaa aaacaaaagg cttgcttttc agccatagag
     3361 gaggtcatca tgtataaaca cttatttttc ctagattcca aaactttaga tcggttgaca
     3421 ccctatattc tagtcttggc ttctgacacc attgctttta atgtttttgt gctaaccttt
     3481 gtatctgcgg tggtttttaa tttcctaaat tccatgctag ctttaatggc tatattcata
     3541 ggggctggct atgtggtcgg attttggtta ctaatactca atgaaaatca aagagcaaac
     3601 taggaaacta gccgcaggct gtacttgagt acggcaaggc gacgttgacg tggtttgaat
     3661 ttgattttcg aagagtataa aatggtttgt tttggaaagg ctagaactaa agaatgacgt
     3721 gtaggaagtc tgtttgttga ggaggataat tttatggagt tttttgataa atttcatgcc
     3781 ttgtgttttg gatttttagt actaataatt gtcattacag ttccttatac gattaaccat
     3841 ggggattttt ttcaaaatga atctgcattg attattgtaa gtcttcttgt aacctcgctg
     3901 agtgttgctt atgctagaaa gtttgaaatg atttcttttg ggatgttaag caagaaacaa
     3961 cttttgcttt tcattgcaat ctttcttcta agtgtacttg agacgctggt ttatattcat
     4021 ttcttcgctg tttcttctgg ctcaggggtc caacacttgg cggaagtcag cagaggaatt
     4081 tccctgtctt tgattttgac tacctcagtt tttggcccca tccaggagga actcattttc
     4141 agaggacttc ttcaaggtgc ggtttttgac aattcttggt tagggcttgt gctaacttcc
     4201 tctctctttt ctttcatgca tggaccttct aatgtccctt cgtttatttt ttatctactt
     4261 gggggcttgt tgctgggcct tgcttataaa aagagccaaa acctatgggt ttctactcta
     4321 gtccacatgt tttacaacag ttggccactc ctatattatt tataaaaatt atgaaaaggt
     4381 aagcagaaga cggtgcttac ctttttcaag ctataatgat acccaagcca atccagaggc
     4441 ttttctttga gaatcgggtt agagtggttg acgaataggc caaaaactag tagaatagta
     4501 aggaaacttt atacggagga aagaaatgga tttgggtgat aatgagctaa cactgactcc
     4561 catacctggg aaaagtggca aggcttatat gggtagctat cctgatggga agcgcatctt
     4621 tgtaaaaatg aacacctctc caatcctacc tggtctagct agagaacaaa ttgctccaca
     4681 attattatgg agtcgtcgtt tggcagatgg gcgtgatatg tgtgctcaag aatggttgac
     4741 aggcaagata ttgaccccct atgatatgaa tcgtaagcaa atcgtcaata ttttaacccg
     4801 tcttcatcgc tcacgtccgt tgatgacaca attgagtcgt ttgggctatg ccatggaaac
     4861 acctgtagat ttactacagt cttggcaaga aacggctcca gatgctttgc gtaaaaatca
     4921 ttttatcagt gaagtgatgg ctgatttgcg tcagactatt ccaggattta gagaggacca
     4981 tgcgaccatt gtccatggag atgtacgaca tagtaattgg attgagacag atagtggctt
     5041 gatttattta gtagattggg attcggttcg cttgaccgat cgcatgtttg atgtggccca
     5101 tatgctctgc cattatattt cagaacatca gtggaaggaa tggttgacct actacggtta
     5161 caagtacaat caaacggtat taagtaaatt gtattggtat ggtcaattgt cttatttgag
     5221 tcagatttcc aagtattata tgaaccaaga tttagaaaat gtcaatcggg agattcatgg
     5281 tttgcgtcat ttccgagaca agtatggaaa gagaagatga gagttagaaa tcgtaaaggg
     5341 gcaacagaat tactagaggc aaatccccag tatgtggtcc tcaatccctt ggaagccaag
     5401 gcaaaatggc gggacttgtt tggcaatgat aatcccattc atgtggaagt tggaagtgga
     5461 aagggtgcct ttgtttcagg tatggccaag caaaaccctg acatcaacta tatcgggatt
     5521 gatattcaaa agtctgtttt gagctacgct ttggacaagg tgcttgaagt tggagtgcct
     5581 aacatcaagc tcttgtgggt agatggttct gacttgactg actactttga agacggtgag
     5641 attgatcgct tgtatctgaa cttttcagat ccatggccga aaaaacgcca tgaaaagcgt
     5701 cgtttgacct acaagacctt tttggacacc ttcaaacgta tcttgcctga aaatggagaa
     5761 attcatttca aaacggataa ccgtggcttg tttgagtaca gtttagtgag cttttctcaa
     5821 tatggcatga aactcaatgg tgtctggcta gatttgcatg ccagtgattt tgaaggcaat
     5881 gtcatgacag aatacgagca aaaattctca aacaaggggc aagttatcta ccgagttgag
     5941 gcagaatttt aagagatagc ctaaaattag gctgtacaag tgcttttgct ttacataagt
     6001 tggcaaacgt gctatactga tagtaagaat atgaaaagtg aggcggggaa atatcttcgc
     6061 ctcttgctta tgaggaggtg gacgcaatcg caacaatcgt agaattagtc agagaagttg
     6121 tagaacctgt catagaagct ccttttgaac tcgtggatat cgagtatgga aagattggca
     6181 gtgacatgat tctcagtatt tttgtagata aacccgaagg aattaccttg aacgacacgg
     6241 cagacttgac agaaattatc agtcctgtcc tagacaccat caagccagat cccttcccag
     6301 aacaatattt cctagaaatt accagtccag gcttggaacg tcctttgaaa accaaggatg
     6361 ccgtcgctgg agcggttgga aaatacatcc atgtcggact ctaccaagcc atcgataagc
     6421 aaaaggtctt tgaaggaact ttgttggcct tcgaagagga cgagttgact atggaatata
     6481 tggacaagac gcataagaaa accgtccgaa ttccatacag tttagtatca aaagcacgtt
     6541 tagcagttaa attatagaaa aagaaaggat agcttttgag gattcaaaag tgaagaaaac
     6601 atgagtaaag aaatgctaga ggccttccgc attttggaag aagacaaggg aatcaaaaaa
     6661 gaagatatca tcgacgcagt agtagagtcg cttcgttccg cttatcgcag acgctatggt
     6721 cagtcagaca gcgtaactat tgacttcaac gaaaaaacag gtgactttac agtttatact
     6781 gtccgtgaag ttgttgatga agtatttgat agccgtttgg aaatcagctt gaaagatgct
     6841 cttgccatta attcagctta tgaacttgga gacaaaatca agtttgaaga agcaccagct
     6901 gagtttggtc gtgtagcagc ccaatctgcc aaacaaacca tcatggaaaa aatgcgcaag
     6961 caaacacgtg ccatcactta caatacttac aaagaacatg agcaagaaat catgtctggt
     7021 acagtagaac gctttgacaa ccgctttatc tatgtcaacc ttggtagcat cgaagcccaa
     7081 ttgtcaaaac aagaccaaat tcctggagaa gtttttgctt ctcatgatcg tatcgaagtt
     7141 tatgtttaca aggttgaaga caaccctcgt ggtgtgaacg tctttgttag ccgtagccat
     7201 ccagaaatga tcaaacgttt gatggagcaa gaaattccag aagtttatga tggaactgtt
     7261 gaaatcatga gcgtggctcg tgaagcaggt gaccgtacga aggttgctgt tcgtagccac
     7321 aatccaaacg tggatgctat cggtacaatc gttggacgtg gtggtgctaa tatcaagaag
     7381 attactagca aattccaccc agctcgttac gatgctaaaa atgaccgcat ggtaccaatc
     7441 gaagaaaata tcgatgttat cgagtgggta gcagatccag ctgaatttat ctacaatgcc
     7501 atcgctcctg ctgaggttga ccaagttatc tttgatgaaa acgacagcaa acgtgccttg
     7561 gtggttgttc cagataacaa gctttctctt gccattggtc gtcgtggaca aaacgtgcgc
     7621 ttggcggctc acttgactgg ttaccgtatc gatatcaagt ctgctagcga atttgaagcc
     7681 atggaagacg ctgcttcagt agagttggaa gtagaaaacg atactgtaga agaataaaag
     7741 ctgctagagg agggaaagat gaaaacaaga aaaatccctt tgcgcaagtc tgttgtgtct
     7801 aacgaagtga ttgataagcg tgatttgctc cgcattgtta agaacaagga aggacaagtc
     7861 tttattgatc ctacgggcaa ggccaatggc cgcggcgctt atatcaaact agacaatgca
     7921 gaagccctag aggcgaaaaa gaagaaggtc tttaaccgca gctttagcat ggaagtggaa
     7981 gaaagctttt atgacgagtt gatcgcttat gtggatcaca aagtgaaaag aagagagttg
     8041 ggacttgaat aagcaaaaga taagtaatct cttggggctt gctcagcgag cagggcgcat
     8101 catatcgggt gaagaattgg tggtcaaggc cattcaagac ggcaaggcca agttggtctt
     8161 tctagctcat gatgctggac ccaatctggc caagaagatt caagataaaa gtcattatta
     8221 tcaagtagaa attgtaaccg tgttttcaac actggaatta agcatagcag tcgggaaatc
     8281 gagaaaggtt ttggctgtaa cagatgctgg atttacaaag aaaatgaggt ctcttatgga
     8341 atagaagagg aggacatgat ttgtctaaga aaagattgta cgaaatcgca aaagaacttg
     8401 gaaaagaaag taaagaagtt gtagcgcgtg caaaagagtt gggcttggat gtgaaaagcc
     8461 actcatcaag tgtggaagaa gctgtcgctg caaaaattgc tgccagcttt aagcctgcag
     8521 ctgctccgaa agtagaagca aaacctgcag caccaaaagt aagtgcagaa aagaaagccg
     8581 aaaaatctga gccagctaaa ccagctgtag ctaaggaaga ggcaaaaccg gctgagccag
     8641 ttgctccgaa aacagaaaaa gtagcagcga aaccgcaaag ccgtaatttc aaggctgagc
     8701 gtgaagcccg tgctaaagag caggcagaac gacgtaagca aaataagggc aataaccgtg
     8761 accaacaaca aaacggaaac cgtcagaaaa acgacggacg taatggtgga aaacaaggtc
     8821 aaagcaaccg cgacaatcgt cgctttaatg accaagctaa gaagcagcaa ggtcagcaaa
     8881 aacgtagaaa tgagcgccgt cagcaagagg acaaacgttc aaatcaagtg gctccacgta
     8941 ttgactttaa agcccgtgca gcagccctaa aagcagagca aaatgcagag tacgctcgtt
     9001 caagtgagga acgcttcaag cagtatcagg ctgctaaaga agccttggct caagctaaca
     9061 aacgcaagga accagaggaa atctttgaag aagcggctaa gttagctgaa caagcacagc
     9121 aagttcaagc agtggttgaa gtcgtccctg agaaaaaaga acctgcagtg gatacacgtc
     9181 gtaaaaaaca agctcgacca gacaaaaatc gtgacgatta tgatcatgaa gaagatggtc
     9241 ctagaaaaca acaaaagaat cgaagtagtc aaaatcaagt gagaaatcaa aagaatagta
     9301 actggaataa caacaaaaag aacaaaaaag gcaataacaa gaacaaccgt aatcagactc
     9361 caaaacctgt tacggagcgt aaattccatg aattgccaac agaatttgaa tatacagatg
     9421 gtatgaccgt tgcggaaatc gcaaaacgta tcaaacgtga accagctgaa attgttaaga
     9481 aacttttcat gatgggtgtc atggccacac aaaaccaatc cttggatggg gaaacaattg
     9541 aactcctcat gatggattac ggtatcgaag ccaaacaaaa ggttgaagtg gataatgctg
     9601 acatcgaacg tttctttgtc gaagatggtt atctcaatga agatgaattg gttgagcgtc
     9661 caccagttgt tactatcatg ggacacgttg accacggtaa aacaaccctt ttggatactc
     9721 ttcgtaactc acgtgttgcg acaggtgaag caggtggtat tactcagcat atcggtgcct
     9781 accaaatcgt ggaaaatggt aagaagatta ccttccttga tacaccagga cacgcggcct
     9841 ttacatcaat gcgtgcgcgt ggtgcttctg ttaccgatat tacgatcttg gtcgtagcgg
     9901 cagatgacgg ggttatgcct cagactattg aagccatcaa ccactcaaaa gcagctaacg
     9961 ttccaatcat cgtagctatt aacaagattg ataaaccagg tgctaaccca gaacgcgtta
    10021 tcggtgaatt ggcagagcat ggtgtgatgt caaccgcttg gggtggagat tctgaatttg
    10081 ttgaaatctc ggctaaattc aaccaaaata tcgaagaatt gttggaaaca gtccttcttg
    10141 tggctgaaat ccaagaactc aaagcagacc caacagttcg tgcgatcggt acggttatcg
    10201 aagcgcgctt ggataaagga aaaggtgcgg tcgcaaccct tcttgtacaa caaggtacct
    10261 tgaatgttca agacccaatc gttgtcggaa ataccttcgg tcgtgtccgt gctatgacca
    10321 acgaccttgg tcgtcgtgtt aaagttgctg gaccatcaac accagtctct atcacaggtt
    10381 tgaacgaagc accgatggcg ggtgaccact ttgccgttta cgaggatgaa aaatctgcgc
    10441 gtgcagcagg tgaagagcgt gccaaacgtg ccctcatgaa acaacgtcaa gctacccaac
    10501 gtgttagcct tgaaaacctc tttgataccc ttaaagctgg ggaactcaaa tctgttaatg
    10561 ttatcatcaa ggccgatgta caaggttctg ttgaagccct ttctgcctca cttcaaaaga
    10621 ttgacgtgga aggtgtcaaa gtgactatcg tccactcagc ggtcggtgct atcaacgaat
    10681 cagatgtgac ccttgccgaa gcttcaaatg cctttatcgt tggtttcaac gtacgcccta
    10741 caccacaagc tcgtcaacaa gcagaagctg acgatgtgga aatccgtctt cacagcatta
    10801 tctacaaggt tatcgaagag atggaagaag ctatgaaagg gatgcttgat ccagaatttg
    10861 aagaaaaagt tattggtgaa gcggttatcc gtgaaacctt caaggtgtct aaagtcggaa
    10921 ctatcggtgg atttatggtt atcaacggta aggttgcccg tgactctaaa gtccgtgtta
    10981 tccgtgatgg tgtcgttatc tatgatggtg aactcgcaag cttgaaacac tataaagacg
    11041 acgtgaaaga agtgacaaac ggtcgtgaag gtggattgat gatcgacggc tacaatgata
    11101 ttaagatgga tgatgtgatt gaggcgtatg tcatggaaga aatcaagaga taagattttt
    11161 tgctcctttc ttaggtggtg agggacgcaa gcaaaccgat ggtttcattg cttatttttg
    11221 agcctagggt ctcaaaaatc ccctgtgatg ggactgataa atcagttcca tcactttcac
    11281 cacggcgaaa gaagcagatg acttcaaatt gaacttcgtt tcaatttaaa ctgaaaatca
    11341 agaagtttaa aatagctagg tctgctggcc tagcttttgg ttcaaagtag agaaaggaat
    11401 atcatggcaa atcatttccg tacggatcgt gtgggcatgg aaatcaagcg tgaagtcaat
    11461 gagattttgc aaaagaaagt ccgtgatcca cgtgtccaag gtgtgaccat cacagatgtt
    11521 cagatgctgg gtgacttgtc tgttgccaag gtttattaca ccattttgag taaccttgct
    11581 tcggataacc aaaaagccca aatcgggctt gaaaaagcaa ctggtaccat caaacgtgaa
    11641 cttggtcgca atttgaaatt gtacaaaatc ccagatttga ccttcgtcaa agacgagtcc
    11701 atcgagtatg gaaacaagat tgacgagatg ctacgcaatc tggataagaa ctaaagaaga
    11761 ggggttgccc ctcttttttg gtggaggaaa ataggttgaa tttgaaatgg aaaaatattc
    11821 ttttaaaata tattgaaact agaatagtac gcctttactt ctaaaaaatt gttagaaatc
    11881 gatttgactg tcctgatcga tttgtcctgt tcttgtttca ttttactata aaaaaggggt
    11941 tctgtatttt ttaatgttat ctaattagaa aatgcttttt ttgtaggaaa tataatatga
    12001 taaggtgtaa aaaagaaata aggagtttgt atatggctga acaagactta gctatgcaag
    12061 tattacaaca agtggtaaaa ctaccagttg ttaaggttga tagttcgaaa tttttagtgg
    12121 ataagttttc caaagaattg ggtccacagg acattcctac cttattggaa caaggtccaa
    12181 cgtctctctt atctcaagaa atcttagatc gagtagctaa tgcttgtatt cgggacaatg
    12241 tattattagc gagtgggact tctgttttgg caggattacc tggagggctt gctatggcaa
    12301 ttaccattcc agctgatgtg gctcaatttt atgctttctc tctgaaattg gctcaagaat
    12361 taggttatat ttatggttat gaggatcttt gggtttcacg agaggagttg agtgaagatg
    12421 ctcaaaatac cctcttgctt tatctaggcg taatgttagg ggtgaatgga actgctgctt
    12481 tgctacgtgc tggtggtata acaattgcca aacaggtaat gaaaacagtg cctaataaag
    12541 ctttaacaaa gacgctttgg taccctattt tgaaaaaagt cttaaaaata tttggtgtga
    12601 atcttaccaa gggagggttg gccaaaggaa tggggaaatt tattcctatc ttgggtggta
    12661 tcatttcagg tggtttaacc tttgcaacta tgaaaccaat gggggaaagc ttgcagaaag
    12721 aattatccaa gctagtcaac tatagtgaag ttcaatatca agaagatgtt gaaacaatcc
    12781 gaaaagaggc tgaaatcatc gaaggagagt aatatgggac tcataaaaac tctagctaaa
    12841 atttatggta attacttttt gaccgtgcaa ggtgtaaaag tgatgaaaac gataaagaaa
    12901 gctgaccatg tcgttgttgg tctgggcaaa ctttttattg cagataagct aatggatacg
    12961 gctcggtggc tcattaagcc agaggagaga gaatgaaatt tttttggtct tcttgctatt
    13021 ctttttatca aaccgattat tgggattgtg aaattctttt ggatgatcat ttcttttgca
    13081 gttcaattgc tgttttacaa gatattggat tggttcttta aacttatcta gatggtaatc
    13141 caagtcgcag aaaactagca ggaaccccac tgctagtttt ttaatctctc tccatatggt
    13201 ataatataag cagtaaaatc attttatact cttcgaaaat ctcttcaaac cacgtcagct
    13261 tcaccttgca gtatatatgt tactgacttc gtcagttcta tccacaacct caaaacggtg
    13321 ttttgagctg acttcgtcag ttctatccac aacctcaaaa cactgtttta agcaacctgc
    13381 ggctagcttc ctagtttgct ctttgatttt cattgagtat tagaacatac aatggaggtc
    13441 gtcatggaca atatcatcga tgtgtcaatt cctgttgcag aagtggtgga caagcatcca
    13501 gaagtcttgg aaattctagt ggagttgggt tttaaacccc ttgccaatcc cttaatgcgc
    13561 aatacagttg gtcgtaaagt atcacttaaa cagggttcta agctagcagg aactcctatg
    13621 gacaagattg tacgcacact ggaagcgaat ggctacgaag tgattggatt agactaatga
    13681 cagatgaacg gattcatgtc ctacgggata ttttgttaga attgcacaat ggcgcctctc
    13741 ctgagtcggt tcaagatcgc tttgatgcga cctttacggg cgtgtcagcc atcgagattt
    13801 cccttatgga gcacgagctg atgaactcgg attcgggcgt cacttttgaa gatgttatgg
    13861 aactctgtga tgtccatgcc aatcttttta aaaatgctat caaaggtgtc gaagtttcag
    13921 atactgagca tccaggtcac ccagttcgtg tcttcaaaga agaaaatctg gctctccgtg
    13981 cggccttgat tcgcattcgt agattgttag atacctatga gtctatggaa gacgaggaaa
    14041 tgctggcgga gatgcgtaag ggtttggtgc gtcagatggg acttgtgggt caatttgaca
    14101 tccattacca acgtaaggaa gaactcttct ttcctatcat ggagcgctat ggacacgatt
    14161 cacctcccaa agttatgtgg ggagtggatg atcagattag ggaactcttt caaacagctc
    14221 taacgacagc caagtcacta ccagaagtgt caattagcag tgtaaaggaa gcttttgaag
    14281 cttttgcgac agagtttgaa agtatgattt tcaaggaaga gtccatcctg ctcatgattc
    14341 tccttgagtc ttttactcag gatgactggc ttcagattgc ggaggagagt gatgcctatg
    14401 gctatgccat catccgtccg tcagagaaat gggtgccaga acgacagatc tttattgagg
    14461 aaaagattgc agaggagcct gtacagctag atacggcaga aggtcaagtt caacaagtca
    14521 tagatacgcc agaaggccat tttaccatta cctttacccc taaggaaaag gaagctgtgc
    14581 tggaccgcca tagtcaacag gcttttggta atggctatct ttcagtcgag caggccaatc
    14641 tcatcctcaa tcatctccct atggagatta cctttgtcaa taaagaagat attttccagt
    14701 attacaatga caatacgcca gctgatgaga tgattttcaa acggacgccg tcccaagtcg
    14761 ggcgcaatgt cgaactctgt catccgccta agtatttgga caaggtcaag gctatcatga
    14821 agggacttcg tgaggggacc aaggacaagt atgaaatgtg gttcaagtct gagtcgcgag
    14881 gaaagtttgt ccacatcacc tatgctgcag tacacgatga aaacggagaa ttccaaggtg
    14941 tactggaata cgttcaggat atccagccct accgtgagat tgatacggac tatttccgtg
    15001 gattagaata aggagaaaaa atgagttacg aacaagaatt tatgaaggaa tttgaagctt
    15061 gggtcaatac ccaaatcatg attaacgaca tggcgcacaa ggaaagccaa aaagtttacg
    15121 aagaagacca ggacgagcgt gccaaagatg ccatgattcg ctacgagagt cgcttggatg
    15181 cttatcagtt cttgcttggt aagtttgaaa acttcaaagt aggcaaggga ttccatgatt
    15241 tgccagaagg cttgtttggt gagcgaaatt attaaacgag aaagattctt gatttttcac
    15301 taaaatcttg atagaatgtt tatgttaaat ccttgtcaga gcagggattt tttattgaaa
    15361 ggattttatc atgtcaaaga aactcaatcg taaaaaacaa ttacgaaatg gcctccgtcg
    15421 cgcaggtgcc ttttcaagta ctgtgactaa ggttgtagat gagacaaaaa aagtcgtgaa
    15481 gcgtgcagaa cagtcagcaa gcgcagctgg taaggctgtt tctaaaaaag ttgaacaagc
    15541 agtagaagct accaaagagc aagctcaaaa agtagctaat tctgtagaag attttgcagc
    15601 aaatttgggt ggacttccac ttgatcgtgc caagactttc tatgatgaag gaatcaagtc
    15661 tgcttcagat ttcaaaaact ggactgaaaa agaactcctt gccttgaaag gaatcggccc
    15721 agctaccatc aagaaattga aagaaaatgg catcaagttc aagtaatttt tcttgagcct
    15781 tgcatttccg aaaaaatctt gctacaatag agccattaga ggtgttttga atcccacatt
    15841 ttacagaaag tggcggcgct gagaagtcca caaatgtgtc aaaactggtt gctaatggat
    15901 gaaaaattga aataaaagtg tctttttgct ttaaagacga gagttgcggg caactgcccg
    15961 aaattgggtg gtaccgcgga taaacacatt cgtccctgtc atgtagatgg cagggctttt
    16021 cttttacgtc ttagtcaaag ggggttgtta tgaagcaatc ttttaacaca agtaaactat
    16081 attatggttt tcctgttttt attttaggat atcaagatta gaattttggc tataacatca
    16141 cgacctgtag ttcctcttat agtctaggag attgggttgt gattggagtc gttgcgagag
    16201 agaatgccgc agagcagatc aaacagtatc aaaaatttac tgtgaatatt tctgatgaaa
    16261 cttctatgct tgcgatggag caggctggtt ttatcagtca tcaggagaaa ttggaacgtt
    16321 tgggagtgca ttatgaaatt tctgaacgaa ctcagatttc tattttagac gcctgtccac
    16381 ttgttttaga ttgtcgggta gataggattg ttgaggaaga cggtatttgc cacatctttg
    16441 ccaagattct tgagcgactt gttgccccag aattcctgga tgaaaaggga cattttaaaa
    16501 atcaactgtt tgccccaacc tatttcatgg gagatggata tcagcgcgtt tatcgctatc
    16561 tggacaagcg tgtagatatg aagggcagtt tcatcaaaaa agcgaggaag aaggatggca
    16621 agaactgagc tgtcagataa aatcgaaaca gaacgtctcg ttttacgagt ccgtactgtg
    16681 gcggatgctg aggatatcca tgcctacgct agtttgccag aggtcgccta tccagcaggt
    16741 tttcctccag tcaagacctt ggaagatgag atttattatc tggagcacat tcttccggag
    16801 cgtaatcaaa aggaaaatct cccagcaggc tacgggattg tcgtcaaagg aacggataag
    16861 atcgctggct ctgtcgattt caaccatcgc tatggggacg atgtgctaga gcttggctat
    16921 accttacact cagactactg gggtcgaggt tatgttccag aagctgcgcg tgccttgatt
    16981 gacttagcct ttaaagattt gggtcttcac aagattgaac taacttgctt tggatataac
    17041 cttcaaagta aacgagtcgc ggaaaagctt ggctttaccc tcgaagctcg cataagagac
    17101 cgcaaagatg ctcaaggcaa ctgctgtgat gatttaagat atgccttgct gaagagtgaa
    17161 tgggaggaat aagatgagcg atgtaaaaga ggaagtaagc tctctatctg agaagcagtt
    17221 acgccaaatt gatgttgagt atgctgaatt aaatgatagt gatattatcg agcgattagc
    17281 ttatttagaa attaacaaca atgaaaaacg tattgtcatc tctgatattg aaccaaccaa
    17341 ggaaataatg tcagtctcgg accaaatttt tgagattcaa aagaattttc aaaaaatcaa
    17401 gaatatgttc gaattgttta tttcagatgt ctcggatttt ttaagtatta aaaataaact
    17461 tgagtcaaag gaattagaaa ttgaagaggc agatgtaaat cgtttcatga ttcatttatt
    17521 atccagtgga aaattgtttg tcgattttaa cgaaaaccaa attaaacaaa aatattccaa
    17581 agatagtgag gagtttgatt gtatacatgg ttttgcaagc tatcagtatg atatcaattt
    17641 tacttatcga ttttgccatt ctttgagaaa ttattcgcaa catactgact taccaataaa
    17701 tgaggtaaaa gctgttagcc cagatgatga gactgttata atagatttct atattgattt
    17761 agattatctt ttaaattcca actttaaatg gaaaaaattg aaaggggagt tgataaaact
    17821 aaaccaagaa acatctaaga ttgacgctat agctctagtg aaagaatact ttaatgctct
    17881 tacagagctc tatggtaatt ataataagtt gtttttaaag ttaaaccata atacattagt
    17941 agatattaaa tcaaagttgg aatcattaaa attgaaacac tctaggtatt atatttcaaa
    18001 gataagcaag tatgatctta aatataatcc tggaaattat actatgtcac cacttgcagc
    18061 atttgctgaa attgaagaga tttatattga actttcaaaa attggtttgg ttaaaattgt
    18121 caataaaagt aattaaggag aacacacatg tctaaagaac tttcatctaa atacaatcca
    18181 gccgaggttg aggctggtcg ttaccaaaaa tggcttgatg ctgatgtttt caagccttca
    18241 ggcgatcaaa aggctaagcc ttattcaatc gttattccac caccaaacgt tacaggtaaa
    18301 cttcaccttg gtcacgcttg ggatacaact ttgcaagata ttatcatccg tcaaaaacgc
    18361 atgcaaggtt ttgataccct ttggcttcct gggatggacc acgcagggat tgccactcag
    18421 gctaaggtag aggagcgctt gcgtggtgag ggcatttccc gctatgacct tggtcgtgag
    18481 tctttcttga cgaaagtctg ggaatggaaa gacgaatatg ccactactat caaggaacaa
    18541 tggggcaaga tggggctctc tgtagactac tctcgtgagc gtttcactct tgacgaaggt
    18601 ttgtcaaaag ctgttcgtaa ggtctttgtg gacctttaca agaaaggctg gatctaccgt
    18661 ggtgagttta tcatcaactg ggacccagca gctcgcacag ccctttctga tattgaggtg
    18721 attcacaagg atgtcgaagg tgccttctac cacatgaact acatgctgga agatggttca
    18781 cgcgcccttg aagttgctac aactcgtcct gagactatgt ttggggacgt tgcggttgcg
    18841 gttaatccag aagacccgcg ctacaaggac ttgattggta aaaacgtcat ccttccaatc
    18901 gctaataaac tcatcccaat cgttggagat gagcacgcag atcctgagtt tggtactggt
    18961 gtcgtgaaaa tcacacctgc ccacgatcca aatgacttct tggttggcca acgtcataac
    19021 ttgccacaag tcaacgtcat gaacgacgac ggaactatga atgagcttgc ctttgaattt
    19081 tcaggcatgg atcgttttga agctcgtaag gcagtcgttg ctaagttgga agaaatcggt
    19141 gcccttgtca aaatcgaaaa acgtgtccat tcagtcggtc actcagaacg gacaggtgtc
    19201 gtagttgagc cacgcttgtc tactcaatgg ttcgtcaaga tggaccaatt ggctaagaac
    19261 gccattgcca accaagacac agaggacaag gtcgaattct acccacctcg tttcaacgat
    19321 accttccttc aatggatgga aaatgtccac gactgggtta tctctcgtca gctttggtgg
    19381 ggtcaccaaa tccctgcctg gtacaatgct gatggtgaaa tgtatgtcgg cgaagaagct
    19441 ccagaaggtg acggatggac tcaggacgaa gacgtcttgg atacttggtt cagttctgcc
    19501 ctctggccat tttcaaccat gggctggcct gaagtcgact cagaagactt taaacgttat
    19561 ttcccaactt caaccttggt aacaggttac gacatcatct tcttctgggt gtctcgtatg
    19621 atcttccagt cattggaatt cacaggccgt caaccattcc aaaacgtcct tatccatggt
    19681 ctaattcgtg atgaagaagg acgtaagatg tctaaatctc ttggaaatgg cattgaccca
    19741 atggatgtta ttgataaata tggtacagat agtcttcgtt ggttcttgtc aaacggctca
    19801 gctcctggtc aagacgttcg tttctcttac gagaaaatgg atgcttcatg gaactttatt
    19861 aacaagattt ggaacatttc tcgctatatc ctcatgaaca atggaggttt gacgctggat
    19921 gtggcgcatg acaatgtcac aaaagttgca acaggtgagg ctggtaatgt gacggaccgc
    19981 tggattctcc acaatctcaa cgaaaccatt gcaaaagtta ctgaaaactt tgataagttt
    20041 gagtttggtg tggctggtca tatcctttac aacttcattt gggaagaatt tgccaactgg
    20101 tatgttgagt tgaccaagga agttctttac agcgacaatg aagacgataa ggtaattact
    20161 cgatctgttc tcctctatac gctggataaa atccttcgtc tccttcaccc aatcatgccg
    20221 ttcgtgacag aagaaatctt tggtcagtac gctgaaggct ctatcgtgac agcagcatac
    20281 ccaactgtca acccagcctt tgaagacctt gctgcccaca ctggtgtgga aagtctcaaa
    20341 aacttgattc gtgctgttcg gaatgcgcgt gcggaagtaa atgtagcacc aagcaaacct
    20401 atcacaatcc ttgttaagac tagcgatagt gacttggaag ccttctttaa cagcaatgtc
    20461 aactacatca agcgctttac aaatccagaa catttggaaa tcgcatcaac catccctgca
    20521 cctgaactgg ctatgtcaag cgtcatcaca ggagcagaaa tctacttgcc actggcagac
    20581 cttctcaatg tcgaagaaga actggctcgt ctcgacaagg aactcgctaa atggcaaaaa
    20641 gaactggata tggtcggtaa gaaactctct aacgaacgct tcgtagccaa cgccaaacca
    20701 gaagtcgtcc aaaaagaacg cgacaaacaa gctgactacc aagccaagta tgatgcgacc
    20761 gtagcacgta ttgatgagat gaagaagttg gtgaaataaa cacagaaaca cggtgatgag
    20821 ccgtgttttt tggtataatg aaatcaatat ctattgatgg agaaagtgat gtccaaacac
    20881 cctcattatg aattgttaaa tttaattggc tacggtcttg ccaagtttga caagcttttt
    20941 ataaaagaat ttcaatgctc tagcaagtcg gagttttatc gctatgtggt ttctctggga
    21001 attgctgaaa caactggagt tgtaaaaaat agaatggatt tatttgatcc ttattttgac
    21061 aataatcgaa aaggttggtg gcagaaagct gaagtttatc gttttcgtaa agatttaatt
    21121 gatatgatgt ttggaaatga agatgttcat agttatgctg aaatagttaa aatgttactt
    21181 gccagtgaag ggaagaaaac aggcataacc atcgttgaaa aaccaatagt tcgaactaaa
    21241 ttcaaacgtc tacaggaaac gggaatggag gctgagaatt attttatcct tcattttgat
    21301 aaagaagaaa aattccaagg tggacagtta accgatgccc gtctttatgg tgatggatat
    21361 gactttcagg tagatgtcca agagtattct taccttgccg aagtaaaagg tatccgaaaa
    21421 tctaaggggc gtgtgcgttt aactgcaaaa gaatttgaaa aagtcaagga gtttcaatcg
    21481 gattttattt tatccttggt cacaaatcta gatgatattc caaagttagt gttaatcgat
    21541 aatcctttaa aacattttga gtttaaaaag aatattatca aaaatgaaat cattgaatat
    21601 agaagcgtag aggatttgta ttagttcccc cttaactttt ccagttgaag gaacgagaag
    21661 tcttgacagg tcaacgactt aatgaactgg aaatcaacgg tattcgtttg actaagtttt
    21721 aagatggcga aatcggtatt gaatttatca gtagtgctga ttataactct tttattattt
    21781 acatgaagta tatatatata tatatatcat agaacctatt gtgaggactt tttatagttt
    21841 aagccagttt ccaaccaatt tcgtgattta ctggtaatga agaaaaacaa ttgaaaggat
    21901 atttctatgc aaccaactta caacattgac aatccaaact tgtcttatga agcgaagcgt
    21961 gatttatggc ggataggttt tggtctgcag aaagttgaca atctagtgcc atcagcgtat
    22021 atggaatctt tggctgagaa acagtcccgg ggagaactga cttatgagca ggtttatgag
    22081 gatgcaacgg cttatcacca tactattgat gcaagtacgg aagaggcaga cttggtttct
    22141 ctacgtattg tagaactatt gtctcgaaga ggctttagct ttagtcctgc gaccttactt
    22201 gctattcata aggagttgtt tcaagatata tttgaaccct ctattccggt ggggcaattt
    22261 cgtcagacca atatcacaaa gaatgaacct gttttgaatg gtgaaagtgt tgtgtactct
    22321 gattactcca tgattcaaat gaccttagat tatgatttta atcaggaaaa acaagttgca
    22381 tatgcgacac taactcaggc ggatgtggtt aaacaaatcc agcattttat ttcaggaatc
    22441 tggcagattc atccatttcg cgaaggaaac actcggacag taacggtctt tttgattcag
    22501 tatcttcgtg agtttggttt tgatattgat aatacaccat ttcagcaaca ttccaaatat
    22561 tttcgtgatg ccttggtatt agataatgca aagattttac agcgacgttc tgagttttta
    22621 acagcttttt ttgaaaatct cttgctcggt ggtcaaaatg atttgtcttc agaaaaaatg
    22681 tatctagatt tagacctcga tttttcataa tccaaatact gagtaaacat tgaattttag
    22741 gcaaaaatga agtaaatatt ctcacaagaa aacgtatatc atcaaagttt taggtgtact
    22801 gaccccaaaa agttagacaa ataatttatc cgaaggattt agttctgtat tgcacaaggc
    22861 taagtccttt tagttttacc ttaattcgtt tattgttgta gtaatcaata tagtctacaa
    22921 tagcttgttc caattgatta agtgatttaa atgttttctc atagccataa aacatttccg
    22981 atttcagaat cccaaagaag gactccatca taccgttgtc ttggctgttt cccttgcgtg
    23041 acatagatgc ttgaattccc ttactcttag gaaccgatga taagaatcgt gtcggtattg
    23101 ccagccttgg tcactatgga gaatcgtatt ctcgtagtac ttctctgtga atgcctgttc
    23161 caacattgtt tgtacttgtt ctaagttggg tgaagttgaa agattatagg cgataatttc
    23221 gctgttaaag ccatctaaaa ctggtgataa gtaaagcttt tgagtacttg ctggaatggc
    23281 aaattctgtc acatctgtgt agcacttttc cattgtttta gatccttcaa attggccttg
    23341 aatgagattc tctgccttct taccaacgtc tcctttattt tcgtttctgt cgcattttag
    23401 cttgtaaatt gagtactttc atcaagcctt gaactctttt atgatttacc agataaccac
    23461 gatttcttag ttctaaatga atacagcgat aagcataatt tcccttgtgt tcgataaaaa
    23521 tggattgaat ttcagcttta agctcttggt ccttatctgg tttgtctagc tgtttcaagt
    23581 gatagtagta ggtcgaacga gctagtttaa tggcttttag aagaagatct aacgaaaact
    23641 cagtcattaa ttcttgaaca atttctgtct ttcttctttc tctttttcct ccttcaatcg
    23701 gagttctctt aactttttta ggatggcatt ctccgatctc aggtactctc tctcttgttt
    23761 tctcaacaat agtatacccg tttttcctgt attgtgctag ccagttaaga agtatcgtac
    23821 gacttgggag gcagtattca agagaaactc tatctttagt ccagccttca tgtcagactt
    23881 tattaatcat ttcttgtttt aaatcaggag aatagtaacg atttttccct tttttgacga
    23941 actctattcc gtaacgatca atcaatttaa tcatgtacct aatattagaa ttgtttatcc
    24001 caaatttatt tgaaagcttc tctaagctat atccttgttt tctaagttca tagatctgaa
    24061 ctttatcatc ataagttaat ttcataataa aaacacccca aaagttagat tttttctgtc
    24121 taacttttgg ggtgtagttc atgtacacct gatatgatgc gttttttgaa ttttatagac
    24181 tgctcgttta aactctattt acctcgtaca ttccggagcg agacggaata ttagccacat
    24241 acaaaatgag tactattagg attttatttt cgtgtacaat ttcagctatt cttgttataa
    24301 tcagcctata ggaatcaagg aggtgactct tatggctgtt tttgtgtctt tggatggaat
    24361 tgtggtagaa gtacttgatg tcttttcttc ttttaatggg gatagtgagt ttttcttgtg
    24421 taaacgtctt aaagacaaga gtcagtttgt tatggaacgc tctcagttcg aggagatgtt
    24481 ccaacttcaa agtagtcgct tgacgacgca agaaaaatta caattgttta cctctgtgtt
    24541 tgctggccgt tatgatgttt atgctaagag ttttatcaat gatcaaggga aaattcagta
    24601 ttttccttcc tatgattgtg gttggaagca gttgctacct gaaaaacgga gtttccagac
    24661 attgacggat tccgttttga aatctcattt tcgtggggag acagctatcg gtatctttcc
    24721 tatgcactta gatgatagct gtcatttttt ggtactggat tttgatgaag gagattggaa
    24781 agaagctggt ttaaccattc gaagaatagc cagggaacgc cagatggaag cccatttaga
    24841 gatttctcgt tcgggtcacg gactccatat ttggttcttc tttgaggaag cgattccgag
    24901 tcgagaggct cgcttgtttg gaaagaaact gatagaactg gcaatgcagg aaagtatgca
    24961 actgtccttt gattcttttg atcgcatgtt tccaaatcag gatgtccttc ctaagggggg
    25021 atttggaaat ttgattgcct tgccttttca aggagaagct taccatcaag tgcgaacggt
    25081 ctttgtggat gaacagtttc agccttatga agaccaatgg aggtatctac aagaaattca
    25141 gagggtttca actgctaaag tggcactgtt aatccaagaa gagttaggca agcaagaatt
    25201 ggacaaggag ttgaagatcg tcttatccaa tatgatccaa cttgaaaaat cgtctgtgac
    25261 acccaagaca ctgtttttct tgaaaaatat ggcttcattt tctaatcccg aattttattt
    25321 aaagcaggct atgcgacagc caacctatca aattcctgag agaatgtatt tatttggaga
    25381 atccgatcat tatttatggt tgccaagagg tttgctgtat ccattgcaag ataaatttaa
    25441 gcaggtatct gtggaagata ggagaaaggt acaaaggtct attagcgtgg aatttaaggg
    25501 agaactcact tttgagcaag agttagccct gtcagatatg acttctaaag aaaatggttt
    25561 acttcatgcg gagactggtt ttgggaagac cgttttaggt gctgctctta tctctgaacg
    25621 gaaaacaaaa acaattattc tagtccataa taagcaactc ttagaccaat ggctagatcg
    25681 cttaaactgc tttttgactt tcgaagagga ggaggctatc cgttatacgg catcaggtcg
    25741 tgaaaaggta atcggctatg ttggacagta cggtgggact aagaaatggc tgagtaaact
    25801 ggttgatgtc gttatgattc aatctctatt taagttggaa aatagtcaaa gtcttttgga
    25861 tgagtatgag atgatgattg tggatgagtg tcatcatgtc tctgccttga tgtttgaaaa
    25921 agttgttgct cagtttagag ggaagtatct ttacggtttg acggctacgc ctgagcgtaa
    25981 gaatggtcat gagcctattg tttttcagag aattggtgag atactccata ctgctgataa
    26041 gagggaaacg gattttaaac ggcaattgca attaagattc acttcttttg gtcatttgga
    26101 gattgaaaag accaaagcaa gtaattttat acagcttagt gattggattg ctactgactc
    26161 agcgaggaat cagttgattc tcaaggatat tctagcccaa gtggcagaag gacggaatat
    26221 cttggtttta gttaatcgaa ttcaacagat agatgtcttt gaaaagttat tgaaagagaa
    26281 agaggttgat gactgttaca ttattagcgg aaaaaccaaa gtccgagaaa gaacgagttt
    26341 actggagacg ttagaacagt tagataaagg gtttgttttg ttgtctactg gaaaatacat
    26401 tggcgaaggt tttgacttac ctcagttgga cacgcttatc ttggcagcac ccttttcttg
    26461 gaaaaataat ttaattcagt atgcaggtcg gattcataga aactacaagg ataagtcttt
    26521 ggtgcgtatt ttcgattatg tggatattca tgttccttat ttagaaaaga tgtttcagaa
    26581 acgacaagta gcttatcgaa agatggatta tcgtgtcatc gagggtgagg agaaacaatt
    26641 cgtttatgtt gatagtagat atgagaaggt gttgagagag gacttagcag gggaaagaca
    26701 ggaatgtctg cttattttac cttatgtgca ccagacaaaa ctgatgaatt ttctaaaaga
    26761 atttaggatt agtcaaattg agatatgtat accagagacg gttgcaaata aagcatggct
    26821 agaccagttg aagagccaga aaattaaagt gtcttttact caatcaaaaa tagtaacgcc
    26881 tattcttttg gtgaataaga ctattgtttg gtatggtgca atgccattat tagggaaggt
    26941 agatgaaatg accatactac gtttggaatc agctagtata gcttctgaac tagtggcagg
    27001 tttacgatag agaaaatttt taaaaatttc tatgtatgac tttcgttttt tagtgagact
    27061 gttgccattg tcacattcga agcacacaaa ataaaaaaat ttctataagt acttgacaaa
    27121 tagattgaaa tatcataaaa taaaaacggt tacagagtta ttaattattt aagcttcatg
    27181 tcaccattaa aaattgaaat aaaaggatgt tatcactaat acaagtgagc aggaacctat
    27241 ttaatcacat cagaagaagt ttcttgatgt tttttaagta ggttcctttt attttaaaag
    27301 ggaaatttta tgatcataaa acgaatacta aaccacaatg ccgtaattgc gcaaagtaaa
    27361 aaagatatcg atattcttct ttttggaagg ggaatagctt ttggaagaaa aattggagat
    27421 aaagtaaatc caattgatat tgagaaaagt ttttttctca aaaatagaga taatatgacc
    27481 cgttttacag agatgtttat taacgttcct ttggagttgg tgtacatcac cgaaaaaata
    27541 attaacctag gtaaaataac attgggtaat aattttgatg agattatcta tataaatcta
    27601 acggatcata tttcttcgag tatagaacgt tataaagaag gagttattat ttcgaatccc
    27661 ctacgctggg aaatctcgaa atattataaa gaagaatttg agcttgggaa aaaggcttta
    27721 caaataataa aaaaagagtt aggtattgaa cttccaattg acgaagctgc attcatagcg
    27781 ctacattttg ttaatgctaa tttagaaaat aattttcaag agtcgtataa aatcactgaa
    27841 ataattatgg gaattgagaa aatcattcaa gatttctatt gtactgagtt taaccaagat
    27901 tctattgatt attatagatt cataactcat ataaaattat ttgcccatcg cttggttgaa
    27961 aatacaactt attgtgacga tgatgatgaa gacttgttag cattaatgaa aaataaatat
    28021 cctagagaat atgaatgtgg tgaacaggtg gcaatgttta tacaaactga gtacaattat
    28081 ttgctgactt ctagtgaatt agtttatttg atggctcata ttcgtcgctt aacaaaaaat
    28141 ttagattaat agaataggag aataccatga gttataaaga tacggtacaa aaaatcctcg
    28201 atgtaattgg aggtgaaaaa aatgtcaata gagttaccca ttgtgtaaca cgtttaagat
    28261 tagaattaaa agatgaaaat ttagtcaatg atgatgatgt gaagaagata ccaggtgtaa
    28321 taggtattat gaaaaagaat ggacaatatc aaattatact tggtaatgat gtagctaatt
    28381 attataaaga attcgttaaa cttggcaatt ttgaatccga ttcagttgtt caagggcaca
    28441 aagggaatat tttagaaaga atcattgagt atatcgctgg ttccatgact ccaatcattc
    28501 cagcaatgtt agggggaggt atgctgaaag tcttggtaat tattttacca atgcttggta
    28561 tattgcaatc agattctcag actattgctt ttttgacatt ttttggggat gctccatatt
    28621 atttcttacc gctgttatta gcttattctg catcacaaaa attaaaagta acatctacat
    28681 tagctatgtc tgtagcaggt gtacttctcc atccaaattt tgttcaaatg gtgcaatcag
    28741 ggaatcctct tagtttattt ggtgcacctg tgacaccagc tagttatggt tcgtcagtcg
    28801 ttccaattct tattatggtt tggttgatga aatatattga aaaaatgatt gctaaattaa
    28861 caccagctgt tactaagagt tttttgcaac ctacgctagt attattagta tcaagctgta
    28921 ttgccttagt tgtagtcgga cctattggag taattgttgg tgaaggatta tcaaatctag
    28981 ttgggcaaat gtatggtgta gctggatggc ttacattagc tattcttggt gctattatgc
    29041 catttattgt tatgactgga atgcattggg cttttgcacc tatttttttg gcggcatcta
    29101 ttgctactcc agacgtatta attcttccag caatgttagg gtcaaactta gctcaagggg
    29161 ctgcttcgat ggctgttgca ttaaagagta aaaataataa tacaaaacaa attgcttttg
    29221 cagcaggttt ctcagcctta cttgcaggga ttaccgaacc tgcattatat ggtgtgactt
    29281 taaaatataa aaaaccgctt tatgcagcta tgattggtgg tggattagcg ggattatttg
    29341 caggtcttac tagtgttaaa gcatatctat ttgctgtccc atctttgata gcgttgcctc
    29401 aatttattta ttctgatgtg ccatcaaata ttgtaaatgc tttaattgtg gcggtcattt
    29461 cggttgttat tacctttgta ttagcttata tatttggaat cgatgaagaa gagagttcta
    29521 gcaatttaga agttaaagct ggagtttcaa ataaaaaaat gatattttct cctatatcag
    29581 gagaaatcat tccgttaagc gatgtccagg ataaaacatt ttcagataaa ctaattggag
    29641 acggagtagc gattatccca agtgaaggta aggtttatgc accatttgat gggaaaatta
    29701 caaatatttt tccgactaag cacgcaattg gattgaagag tgatgagggt gttgagttac
    29761 taattcatat tggattagat actgttgagc taaaaggtca aggttttatt agtcatgtag
    29821 aagaaggaga cagagttttc aaaaatcagt tgatttttga aatggacttg aatttaatca
    29881 agactaaagg ctacgaaaca gttacaccag taattgtaac gaataccaat gattttctag
    29941 atgtattagt attacctaat aatcagacaa tcgagcattc taaggaatta ctggtaatat
    30001 tataatggag gaaagttatg accatttttc cagatgattt tctttggggt ggagctgttg
    30061 cagctaatca agtagaggga gcatataatg aagatggtaa gggcttatca gttcaggatg
    30121 tgttacccaa aggtggatta ggagaagcaa cagaaaatcc tacagaagat aacttaaaat
    30181 tgataggtat tgatttttat cataaatata aggaagatat atccttgttt tctgaaatgg
    30241 gctttaatgt ttttcgtact tctattgcat ggagtagaat ttttccaaaa ggagatgaag
    30301 aagaacctaa cgaagctggt ttgaaatatt atgatgaatt gtttgatgaa ctacatgctc
    30361 acgggataga gccacttgta actctttcac actatgagac tccattatat ttagcaagaa
    30421 aatatcatgg atgggttgat aggagaatga ttcattttta tgaaaaattt gctcgaacag
    30481 ttttagaaag gtataaagat aaagttaaat attggcttac atttaacgaa gtaaactctg
    30541 ttttggaatt accatttact agtggaggaa tagatatacc taaggagaat ctttcgaaac
    30601 aagaattata tcaagctata catcatgaat tagtcgcctc aagtttggtt acaaaaattg
    30661 ctcgtgagat taattcagag tttaaggtgg gatgtatggt attagctatg ccagcttatc
    30721 caatgactcc aaatccaaaa gatgtatggg cgactcatga gtatgagaat ctaaattatc
    30781 tattttcaga tgtgcatgtt agaggttatt atccgaatta tgcaaaaaga tattttaagg
    30841 aaaatgacat taacatagag tttgcagctg aagatgcaga gttattaaaa aattatactg
    30901 tagatttttt atcctttagc tattacatga gtgtgactca atctgctatt ccaacacagt
    30961 ataattcagg agaagggaat attattggtg gtttagtaaa tccttattta gagtcttcag
    31021 agtggggatg gcaaattgat ccaattggac tacgtataat tttaaataga tattatgacc
    31081 gttatcaaat cccattattt atagtagaaa atggattagg tgctaaagat caactaataa
    31141 aagatgaact taataactta accgtccaag atgattatag aattcagtat atgaaagaac
    31201 atttattgca agttgctgaa gctctacagg atggtgttga aattatgggc tatacgtctt
    31261 ggggatgtat tgactgtgtt tctatgtcca ctgcacaact ttctaaaagg tacggtctca
    31321 tttatgttga tcgaaatgat gatggaaatg gcacattcaa tcgatataag aaaatgtcct
    31381 ttacttggta taaaggagtg attgaatcaa atggagaatc cttattcaaa tagtttgttt
    31441 attgatgatt agatattatc acggttaagg caacatctca ttaaatatga aataaagagg
    31501 tttggaagac atcaaattct aaacctcttt attttatagg gggattaatt aatttaattt
    31561 tgttacagag agccgattat aaa
//
LOCUS       DAVLGK010000023        30720 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLGK010000023 DAVLGK010000000
VERSION     DAVLGK010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.023"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            49..981
                     /locus_tag="VXE01_001179"
     CDS             49..981
                     /locus_tag="VXE01_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750085.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDDKFKDKATLENNVKEINKQIDFIKKVDETFKQKKLDE
                     TVKSLTDIADKFQKQIDVLKKEEEQKASDKAKEDKKKEESTSSQSSNSSSQASSSSFS
                     SYSGNSDYAPEQTYTADNSQSYSGSTGGDNSNYKAPAATDNGGNDGYILGHVTGADGS
                     QRDFYFNRSNGDVRDTSGNHVGNFGGGITDFRQR"
     gene            complement(1084..1761)
                     /locus_tag="VXE01_001180"
     CDS             complement(1084..1761)
                     /locus_tag="VXE01_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV0750086.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGL"
     gene            complement(1745..2284)
                     /locus_tag="VXE01_001181"
     CDS             complement(1745..2284)
                     /locus_tag="VXE01_001181"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV0750087.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(2296..3426)
                     /locus_tag="VXE01_001182"
     CDS             complement(2296..3426)
                     /locus_tag="VXE01_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV0750088.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGIFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(3494..4192)
                     /gene="dapD"
                     /locus_tag="VXE01_001183"
     CDS             complement(3494..4192)
                     /gene="dapD"
                     /locus_tag="VXE01_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV0750089.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGSVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(4422..5333)
                     /locus_tag="VXE01_001184"
     CDS             complement(4422..5333)
                     /locus_tag="VXE01_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0750090.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(5398..7863)
                     /locus_tag="VXE01_001185"
     CDS             complement(5398..7863)
                     /locus_tag="VXE01_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0750091.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            8005..9261
                     /locus_tag="VXE01_001186"
     CDS             8005..9261
                     /locus_tag="VXE01_001186"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV0750092.1"
                     /translation="MHIFDELKDRGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(9339..11402)
                     /locus_tag="VXE01_001187"
     CDS             complement(9339..11402)
                     /locus_tag="VXE01_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0750093.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(11404..11682)
                     /locus_tag="VXE01_001188"
     CDS             complement(11404..11682)
                     /locus_tag="VXE01_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750094.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            11834..12682
                     /locus_tag="VXE01_001189"
     CDS             11834..12682
                     /locus_tag="VXE01_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0750095.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTITILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAS
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13481..14053
                     /locus_tag="VXE01_001190"
     CDS             13481..14053
                     /locus_tag="VXE01_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750096.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNRRINF"
     gene            complement(15098..17356)
                     /gene="glgP"
                     /locus_tag="VXE01_001191"
     CDS             complement(15098..17356)
                     /gene="glgP"
                     /locus_tag="VXE01_001191"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV0750097.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTSTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGDENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(17382..18899)
                     /gene="malQ"
                     /locus_tag="VXE01_001192"
     CDS             complement(17382..18899)
                     /gene="malQ"
                     /locus_tag="VXE01_001192"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV0750098.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLGASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            19450..20721
                     /locus_tag="VXE01_001193"
     CDS             19450..20721
                     /locus_tag="VXE01_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0750099.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            20832..22124
                     /locus_tag="VXE01_001194"
     CDS             20832..22124
                     /locus_tag="VXE01_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0750100.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            22126..22968
                     /locus_tag="VXE01_001195"
     CDS             22126..22968
                     /locus_tag="VXE01_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0750101.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            23221..24021
                     /locus_tag="VXE01_001196"
     CDS             23221..24021
                     /locus_tag="VXE01_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV0750102.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQTPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            24031..25017
                     /locus_tag="VXE01_001197"
     CDS             24031..25017
                     /locus_tag="VXE01_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0750103.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNGNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            25153..25233
                     /locus_tag="VXE01_001198"
                     /pseudo
     CDS             25153..25233
                     /locus_tag="VXE01_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(25354..26295)
                     /locus_tag="VXE01_001199"
     CDS             complement(25354..26295)
                     /locus_tag="VXE01_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0750104.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(26273..28036)
                     /gene="aspS"
                     /locus_tag="VXE01_001200"
     CDS             complement(26273..28036)
                     /gene="aspS"
                     /locus_tag="VXE01_001200"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV0750105.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVRGVDFKVFSEAPAVKAIVVTGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALVLEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            complement(28271..28351)
                     /locus_tag="VXE01_001201"
                     /pseudo
     CDS             complement(28271..28351)
                     /locus_tag="VXE01_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(28387..28617)
                     /locus_tag="VXE01_001202"
     CDS             complement(28387..28617)
                     /locus_tag="VXE01_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750106.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(28635..29276)
                     /locus_tag="VXE01_001203"
     CDS             complement(28635..29276)
                     /locus_tag="VXE01_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0750107.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(29288..29968)
                     /locus_tag="VXE01_001204"
     CDS             complement(29288..29968)
                     /locus_tag="VXE01_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV0750108.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVAIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            complement(30024..30221)
                     /locus_tag="VXE01_001205"
     CDS             complement(30024..30221)
                     /locus_tag="VXE01_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750109.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(30221..30427)
                     /locus_tag="VXE01_001206"
     CDS             complement(30221..30427)
                     /locus_tag="VXE01_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0750110.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(30437..30691)
                     /locus_tag="VXE01_001207"
     CDS             complement(30437..30691)
                     /locus_tag="VXE01_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750111.1"
                     /translation="MKKLENKIKRLERKEKGNAEMSRLLQEMIGKEPIITGVYIGPDN
                     WEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFDGE"
BASE COUNT         9471 a         6698 c         5648 g         8903 t
ORIGIN      
        1 gtaattttaa ttttaaagta attgcggaca ctatcaaagt aaaagattat ggagaacaaa
       61 tttgtagaat ttatcgaaaa caataaaaaa gtaatcattt catcagttgc agttggtgtt
      121 gtattggtat tagggtttgg atggtattca tataaccaac aacaagcaga acaacaagca
      181 aaaattgtac aattagaaaa agatagcaaa tcagacaaag aacaagttga taaactattt
      241 gaatcatttg atgcatcttc agatgaatct atttctaaat taaaagaact atctgaaact
      301 tcacttaaaa ccgatgcagg taaagactat cttaataaca aagtcaaaga atcatctaaa
      361 gcaattgtag attttcattt gcaaaaaggt ttggcttatg atgttaaaga ttcagatgac
      421 aaatttaaag ataaagcaac cttagaaaat aatgtaaaag aaatcaataa acaaattgat
      481 tttatcaaga aagttgatga aactttcaaa caaaaaaaat tggatgaaac tgtaaaatct
      541 cttacagata ttgcagacaa attccaaaaa caaattgatg ttctgaagaa agaagaagaa
      601 caaaaagcat ctgacaaagc taaagaagat aagaagaaag aagaatcaac ttcatctcaa
      661 tcttcaaata gttcatctca agcatcaagc agttctttta gttcatattc tggtaattca
      721 gattatgctc cagaacaaac atacacagct gataatagcc aatcttattc aggttcaact
      781 ggtggagaca atagtaacta taaagcacca gctgctacag acaacggagg aaatgatggc
      841 tatattcttg ggcacgtaac tggtgcagat ggatcgcaaa gagattttta ttttaaccgt
      901 tcaaacggag atgttcgtga tacaagcggc aatcacgtag gaaactttgg agggggcatt
      961 acagatttta gacaacgtta ataactattt tagggctgtg ttgtttcgaa tggttccaaa
     1021 acacattaaa agctactcat tttttaagta gcttttttct tattcaagtt tacatattag
     1081 ttgtcacaac cccattccct tgtagaaaag caaaatggcg agtcctacga acaagactac
     1141 cgctcctaat ctctggctgg tattatacat ccgtttttct cctctaactg gaaagataac
     1201 tgctagaaat gcgccaccaa ctgcaccacc gatatggcct gctaggctga ttcctggaat
     1261 cagaacactt ccaataatgt taaccacaaa aagtgtcaga taggattgcc ctagctgttg
     1321 gatataagga ttgcgagttg catagcgaag aacaataatc gcggcaaata gcccataaag
     1381 agaggtagag gcgcctgctg ctaaggattt aggactaaat acaaaaacaa agagattgcc
     1441 catcattcct gataagagat agagaaaaaa gaactgctta gagccgaaaa tctcctctac
     1501 ctgccttcca agataataaa gtgaaagcat attaacaatg aaatgttccc acccaatatg
     1561 aacaaaaatg gcagacaaga gacgccaaac ctgctcggga aagaggcgaa tagctggccc
     1621 atacatggct ccaaatcgaa ataatgtatc tgccctgtca aagtttccgc ctgcagtgac
     1681 caacattagt aaaaatacca aggccgtcac taagaggaag aaactcgtca cagggtaacg
     1741 tctatcaaag atttccttca tcaattaata cctcctgaac aggaatatca tggttttcag
     1801 gtataaagtc ctgaatttga caaggatata tcgtactcaa agtacgacca gaaaaatgtt
     1861 ccaaatagcg gtcataatag cctccaccgt atcctatccg atatcctttc gtcgtaaaag
     1921 ccagaccagg aacatgaatc aaatcaatct gagatgcatc caccacttcc acatctccct
     1981 gtggctccag taaggcaaag gcagttttta ccaactgttg cggatcatag accacaaagt
     2041 ccatgcgccc cttgggataa gttttgggta ttaaaacctt cttgccgtcc ttcagcgcct
     2101 gctcaatcag ttcccgcgtt tgaaactcat gagaaaaaga gaggtaggtt gcgatgacct
     2161 tggcttcttg gtagaaggga tggtgtaaaa gccgctcggt taaagcttgg tctatagcct
     2221 gtttttgctc ttgagatata gccttcattt catgcaagac ttgcttgcgt aattccgatt
     2281 tcatagacaa gccctctatt ctgctgcctt ctttttcagg aaactagaca ccgcagccac
     2341 cccaatagct aagacttctt ccttaggact catttgaggg tgatgaagag cgtagggact
     2401 atcgataccc agccaaaaca tcacgccatc aacctttgaa aggagataac caaagtcctc
     2461 gcctgtcata gcaggttcga tatcaatcaa ctcgattccg tctttttcgt caaagaagtc
     2521 catcagttca cgcgccaagg ctggattgtt ctcaacaggt aggtatccac cttgtttgag
     2581 ttccacttcg acttccatat caaaggcagc tgcaacccct tctgcaactg tttttaccct
     2641 cttttgcacc aagagactca tgtcctgtgt caaggcacga atagttccat gtaaaaaagc
     2701 tgtgtctgtg atgacattgt tggtggttcc agcttgaaaa atgccgaagg tcaccactgc
     2761 tccctcgatt gggttgacat tgcggctaac aactgactgc acttgggtca caaagtaact
     2821 agccgccacc aaggcgtcat tggcttcatg aggaaaagct gcgtggccac ctttgccttt
     2881 gaaacggatc ttcacctcgc aagttcctgc aaagagtgta tgagtattag tcgcaatctg
     2941 gccgactttc aaatctggac gaacatggag accatagaat tggtttggca accaatctcc
     3001 aaaagcaccg tcctcataca tgagcatacc accagcttca ttttcttcag caggctgaaa
     3061 tagaaagagc agattattct tgggttgctc ctcaagggcg cgctcaagac agcctaaggc
     3121 aatggtcata tgaaaatcat gaccacaggc atgcatgcga ccttggtgtt gagaagcaaa
     3181 aggtagacct gtttgttcga cgataggcag gccatcaata tctgtccgcc aaccaatggt
     3241 tcgctccggc tgacttccct gcaggtagac caaaatccct gtccgccaag tacgaatttg
     3301 aacaaaatcc ttgcccgtag tcaatttctc aatcacatcc agcaaataag cctgagtctt
     3361 gaactcctcc aagccaatct ctggtatctg gtgtaaatct cgtctagtct gaatcaaatc
     3421 taacatctat ctgtcctccg atatagcaga aagaggctgg aaaaagggtt ccgcctcttt
     3481 tttactttta caattacaag gtacgaagcg catcctctag cgctgttttt tgttgggttt
     3541 gggcatcaat ttctttgatg atacgagctg gaacacctgc tactaccacg ttttctggga
     3601 catcttgggt aacgatagct cctgcagcga caactgaacc actaccgatt tggactcctt
     3661 cgataaccac tgcattagca ccgataagaa cattgtctcc gacacggact ggttcagcac
     3721 tagctggctc aatcacacct gccaaaactg cacctgcacc aacgtggcta ttttttccaa
     3781 cgatggcacg gccaccaagg atggcaccca tgtcaatcat ggttccagca ccgatttcag
     3841 caccgatatt gataacagat cccatcatga taacagcatt gtcaccaatt tccacctggt
     3901 cacggataat agcacctggc tcgatacgag cgttgatagc acgcttatct agcaaaggaa
     3961 ctgcagaatt acgagcatct tgctcgacaa cataatcttg attttctacc aaaccttcaa
     4021 gaagcggagc cacgtccttc cagtctccga ataggacatt tcctagtttg acaacagagc
     4081 taggcacagc agttgcgagt tgcccctcaa aggttacttt gacactggtt ttcttttcag
     4141 cattggcgat aaattggata atttcttgag cgttcatttt tgtagcagtc ataggtgcct
     4201 cctggttcgt tataatgata cctattctac caaaaaaggc ctcaaatttg aaaccttttt
     4261 gtctgttttt aggtatgatt ttttagggat gtgagataaa acgtgctgtc ggtaaaagca
     4321 agcccctacc gatacaacct aaaaacactc ttcacaacta tctccccgtg ttttattgac
     4381 tattctagta tagcacactt ttagaattaa gaaaagactt tttatctact ttctttcgct
     4441 tcttctatag acaaaaatat catgggtaaa ataatcaagg ctatagctag aaggagggac
     4501 caatccacta ctaatcctaa gaacaaaaca ctcaagagag cagaagagag aggttcactg
     4561 gcactgataa cggcaaccac caaaggagaa accaaggaca cagccttcat ggaaatgaaa
     4621 aaagcaaaag ccgttccaaa gaaagcgata atgaggcaaa tcaagatact ccaaatatca
     4681 agagtaaagg aaagctgata aaccggcgag aggacattgc taaacaaacc ggccaaaatc
     4741 atcccccacc caaccgtagg aacaaaacca taacgcttag caaaaggttg gggcaagata
     4801 acattaaaca taacacccat ggcactcagc aaacctgtta taagagctag cggcgtcatg
     4861 gataactgag agagatctcc ctttgtcgcc atcaagcaaa cacccagcat ggcaaccaaa
     4921 acatagaaaa cagcgctttt tgacgctcgt ttttgataaa ccaagcgatt gtaaaagagg
     4981 ataaagacag ggctaataaa ctgtaaaata gttgctgtcg tagcatttga gtattctaca
     5041 cagagataga aaaaatactg gactgaaaaa atccccaaaa tagcataggc taaaaagggc
     5101 aggtaatttt tcttgtctcg ccaaatatct agcacttgcg attttaattg tattgcagac
     5161 caaatgagta caagactccc tgccagtgtc aaacgcatag aggtaatcca gcccgaagac
     5221 acctgataat gagtaaagaa gtactctcct aaaattccac agattcccca tattaagccg
     5281 gataggagcg aataaatttt tccgttaaca atctttttct gatactgatt cataccctta
     5341 ttgtaacacg aaaggaaaaa agtggcaatc cattgattgg ccacttcatt tagagaatta
     5401 tcgtctcgcc cttgaagaag aaggtcgtgt agtacttgag ttactgctat cgctagaact
     5461 actacttgaa ctgctggagc tggatggagt tggtagactc cccacaatac tagaccaagc
     5521 attctgataa tccgcatcac ttccgccaat agcaaagcga taacttgtcg ctggcgctcc
     5581 tgacttatta gcccaatagc tggtaacagt cgaacctgtg acctctacct cttttccttc
     5641 aacagaaacc ttccctggtt tttgacctgt tgatttcaag acttccgatt tcactacact
     5701 aggatctaaa gcaaagcgct cgtttcccca aatgcttggg gaagcttgct gaatcgcatt
     5761 tactagatga gccatgtaat tagagttatt agaataacct gctctacgtg acaatgaatg
     5821 attatcatca tgcccaatcc agccacctag ggttaatcta ggtgtcgaaa gcatgagcca
     5881 catattttcg tcttggttgg ttgtaccagt cttcccaatc caatctgcat tagccagagt
     5941 aggatttaaa gaagtcaggt tagacttgaa ggttgttgtc acacgagagg atagaacttc
     6001 tcgtagcaat ccctgcataa tcgtcgcagt agcttttgaa tagacttgaa ccggtttatc
     6061 ctgatactca tacaccactc taccatctgc tgcttcaatc tttgaaatca catgcttctg
     6121 atgataaact ccattattag ctaaggtctg atagccattg gtatgctggg caactgtgac
     6181 ttcaatacca ccacccattg gcaagctctc aataccgtac tcaggaatct cgtaacccat
     6241 cttttccata taacccttga catcaacacc cttttcacga agcatacgat aggtccagta
     6301 agcagggata ttccatgaat agttcagagc ttctcccaag gtcatcattc ctgttccctt
     6361 gctattagca tacataatcg gattgccatt agcaaagttt gttggatagt tagatagaat
     6421 cgtttcactt cccatcaagc cctggtcaat agcaataccg taggccagca agggcttggt
     6481 agtagaagct ggcgaacgtt tggtatcaaa ggcatgatta ttttgatttt cttgataatt
     6541 acgaccacct acaaagccta gaatagcacc tgtttggttg tccatcaaga cattccctac
     6601 ttctacacga cctgttccat cgtctaaaag atagccataa tcagcaaccg cactttgcat
     6661 ggcagaatga attttctgat ctatggtagt agtaatctta taaccaccat tttcaatttc
     6721 cttggctgcc aaatctcgat aaaacttctg agttgcctca tttttcaact ccttagcgga
     6781 gacattgtct ctctgagcta gatagtcata catacgttct tgagcttctg ccaaagttgt
     6841 aaagtataaa tagtctcgtg aaattcctgt aaccgtgccc gatggtaaaa agtcctgttt
     6901 aaggtcataa tccttgtact gagaatactc gtctttgctt aatgcacctg tacgatacat
     6961 actgtaaaga actgccttag cccgtcttaa gccaatttct aggtcttcat cactcttcaa
     7021 ctccccagta ttttcataag gagagtaagt aatgggactc tgtggaagtc ctgctaaaaa
     7081 tgctgcttga ggaacagtca actgactggc atctacaccg aaaattccct cagctgcttg
     7141 ccgagcccct gcaatattct gtcccttatt atttcggcca aagggagcca cattgagata
     7201 ggtcgttaaa atctcatctt tattcatggc gcgttccaag gcaagagcat ccacaatctc
     7261 tgccgcctta cgagccaagg tcggcgcatc cccaacaacc tgctgtttaa ttagttgctg
     7321 ggtcaaggtt gaacccccac tagaggaacc caaacctaca aatttcccca aggtcgcacg
     7381 aatcaccgcc ttgggtacta cacccttatg ttctttaaag tgttcatctt ctgtcgcaat
     7441 gatagccttc ttcagatttt ccgaaatttg ctcagatgag atagaagtgc gcaacaaatc
     7501 actctctatg gaagcaatca ccgtcccgtc cgaataggta atctctgaaa tagaagagat
     7561 gtccttgacc tgattcacca attcttctgt ctgaggcacc cgaaccttgt caaataaggc
     7621 cactccgtat cccaaagcaa tcccagctcc caacattcct cctagaaaac cgagtacaaa
     7681 gagtaagtta aataaggctt ttatactcag taaaatagct gggaaaatgg ctgacttatc
     7741 taaggtttta gattttttgg tacttgaacc tttcttgcca ggtctagctg attttttatt
     7801 tttttgtttt tgctggaaaa attccagcat ttttcgtttt aattcattta attgattttg
     7861 catggatttc ctcactctat ctattatacc acaaaaggga aattttcaat aaaatagcca
     7921 ctttcttccc tattctgcta ggctattgcc caagtttgtg atacaatagg tagaaacaat
     7981 aattttaaaa aggagaaaag acacatgcac atttttgatg agctaaaaga tcgtggtttg
     8041 atatttcaaa cgactgatga agaagctttg cgtaaagccc tagaagaagg tcaagtttct
     8101 tattatactg gctacgatcc aactgctgac agccttcacc taggccacct tgtcgcaatc
     8161 ttgacaagtc gtcgcttgca actagcaggt cacaaacctt atgcgctcgt tggcggtgct
     8221 acaggtctca tcggagatcc gtccttcaaa gatgctgaac gtagtctcca aacaaaagac
     8281 acagtagatg gctgggtcaa gtctatccaa ggacaacttt ctcgttttct tgactttgaa
     8341 aatggcgaaa acaaggctgt catggtcaac aactacgact ggtttggcag catcagcttc
     8401 attgacttcc tccgtgacat tggaaaatac ttcacggtca actacatgat gagtaaggaa
     8461 tctgttaaaa aacggatcga aacaggaatt tcttacactg agttcgctta ccaaatcatg
     8521 caagggtacg acttcttcgt ccttaaccaa gaccataatg tcactcttca aatcggtggt
     8581 tctgaccagt ggggaaatat gacagctggt accgaattgc ttcgtcgtaa ggcggacaag
     8641 actggtcacg ttatcactgt tccactaatc acagatgcaa ctggtaaaaa atttggtaaa
     8701 tcagaaggaa atgccgtctg gctcaatccc gaaaagactt ctccatacga aatgtaccaa
     8761 ttctggatga acgtgatgga cgctgacgct gttcgcttct tgaaaatctt tactttcttg
     8821 tcacttgatg agattgaaga tattcgtaaa caatttgaag cagcgccaca cgaacgcttg
     8881 gctcaaaaag tcttggctcg tgaagttgtt acacttgttc acggagaaga agcctacaaa
     8941 gaagcactta acatcactga gcaactcttt gcaggaaaca tcaaaaacct ttctgtcaaa
     9001 gagctcaaac aaggacttcg tggtgtgcca aactaccaag tacaggcaga cgaaaacaac
     9061 aatatcgtgg aactgctcgt ctcatctggt atagttaact caaaacgcca agcccgtgaa
     9121 gacgtccaaa acggagccat ctacgtaaac ggcgaccgca tccaagacct tgactatgtc
     9181 ttgagtgacg ctgataagtt agaaaatgaa ctgactgtta tccgtcgtgg gaagaaaaaa
     9241 tactttgtat tgacttacta aactattcaa catttatcta taaacaaagg agttaacctc
     9301 gagaaaggta actccttttt gctgttaata actctcatct atctattttt aatagacagg
     9361 ctacgcagga caatgcgcaa ggttgttaga ttatgtaaga tagagagatt tgaaggactg
     9421 aaccaattaa ataagccaaa gccaatcaaa ctactattta cgacaacggt atcctgaata
     9481 tttttcttga tgagtgtttg caaagatgat gataacgaat ccaactcttg gaagaaatcc
     9541 aaacgattat ctaacaataa gatatcactc atctgcttag aaatatctgc actctcattc
     9601 atcaccacac cgatatctga tagagttaaa gccgctgagt cattcaatcc atctccgacc
     9661 atcaaaatag tgtgacctgc tttctgcagt ttctctacta actcaaattt cccatcaggt
     9721 ttcaagtctg tatagacctg atcaaagggc aaatctttga ctaattcctc tgtcctaatc
     9781 aaggtgtctc ctgttgccag aatcaatttt ttcccctgtg ccttaagttt atccaaggct
     9841 gtttttgctt cttttctcaa aggagtatga atgcagaaca ttccaatcaa ttcattttga
     9901 taagccaaga ataagagatt gtagtgactc ttgtactctt caattaaagc attttgttct
     9961 gaactgatat gaatctgctc atcctgcatc aagacataat tcccaataag aactggttgg
    10021 ccatctatat gagatttgat ccccttgctt gcgatatatt ggagtttccc atgcatttcc
    10081 tcatgttcaa ttccctctat ctcagcttgc ttgacgatgg cattagcaat aggatgataa
    10141 atgtgttcct caagacaggc actgattctg agaatatctt cctcactata gtctccaaaa
    10201 ggtaacacct tttcaactat aggataacta gttgtgattg ttcctgtctt atcaaacaag
    10261 aaagtatcaa cttccagata tttctccaga acatctccat ccttaatcac catttcacgg
    10321 ttcaaccctt ccttgataac tgtcaaataa gctacaggag tagagatttt caaagcgcag
    10381 gagaaatcga ccaataggaa agaaatagcc ttagaaaaag aacctgtcaa taggtaagtc
    10441 agcccagccc ccaagaaatt atatttgacg actttatccg ccatcttgat gaaatagcgt
    10501 tgtttcgttt tcttgttttc ttcagatttc ttcatcaact caatcagctg taaaatacgg
    10561 ctgttcatct gattatctgt tacacgaatg cgtaactctc cagtttctaa tactgtattt
    10621 gcacaaacca aatcagactc tcttttttca actggaaaac tctctcctgt caaggaactt
    10681 tcgttgacca tacctaaacc tgaaactact tgtccatcaa acagaatttc atttccttga
    10741 gataagatca agacatctcc tatttgaaca tcggaactct tgatactaac aaccgtatcg
    10801 ccctgtacta ggaatacatc gctctctttt gcaagaagac tctgttctaa atctgttgca
    10861 gtttttttca aggaccactg atctaaatga ttccccaaat caagcataaa catgatattg
    10921 ctagctgtct ttgattggtt cataaacaaa gacaataaaa tagccgaaca gtccaagact
    10981 tccatcgtta gttccttacg cgctagtgtt tgataggctt ctctaatata acccaaagcc
    11041 tgataacaag tccatatata gcgaatagga tacggcacaa aactacgaaa aagtacacgc
    11101 ttaaccgctg cacctgaaac aatagaataa gcactctctt ctctacgaat gggaagagtc
    11161 atcaactcag aaactttccc tttatcaatt ctttttaaaa aggcttctgc attatctaat
    11221 acagaaaagc cttcttttat gcgtagagta aagtgctgtt gatccatgta aaactggata
    11281 gactcaatcc ccttttcatc tctcgccaag gaacgaagat agtcttgaat atccaaggta
    11341 agtgaaaaag aagatgatag tcggatatgt tggtatcctc tatgtagcac tttaaaagac
    11401 atattattca cctataaggc tatctaattg ctcttctttt ttctcttgct cgtacaaata
    11461 tttggcatct tgcaagacat cgtctccatg ttgcttcaca acagaaacag atgcatctag
    11521 ctcgtctttc aacttgtaag ccttagccaa agctttagaa taaccttttt tagcttcctt
    11581 acttgctaag attttcaaac caagggtacc aaatgcgaca ccacccaaaa ataatgaaga
    11641 ttttttcgca acttttgcaa cggttaatac ttcttttaac atacttattt cctccttatc
    11701 attattatat agcaatttag atataaaagc aatttcattc tataaattgg agaattagtt
    11761 ttatttctac tgaatctccc atctacttat tcctaaagtt gctttcattt gcctcttttg
    11821 atacacttaa actatgaata caaatctcaa gcccaaactt cagcgttttg cttctgcgac
    11881 tgcctttgcc tgtcctatct gtcaagaaaa tctgactctg ttagagacta atttcaagtg
    11941 ctgcaaccgt cattcttttg acttggcgaa atttggctat gtcaatctag cacctcaaat
    12001 caagcaatct gctaactatg acaaggaaaa ttttcaaaac cgtcaacaaa tcctagaagc
    12061 cggcttttac caagctatct tagatgctgt atctgacttg cttgcaagct caaaaactac
    12121 cataacaatt ttggatatcg gttgtggtga aggattctat tctcgcaaac tacaagaaag
    12181 tcactctgaa aaaactttct atgcctttga catctccaaa gattcagtcc aaatcgctgc
    12241 taaaagtgaa cccaactggg cagtcaattg gttcgttggc gacttggcac gccttcctat
    12301 aaaagacgct agcatggata tcctgcttga tatcttctca cctgccaact atggagaatt
    12361 tcgtcgcgtt ttatccaaag atggtatctt gataaaggtt atcccaactg aaaatcacct
    12421 caaagaaatc cgtcaaagag tacaggacca gctgacaaac aaggagtatt ctaaccaaga
    12481 tatcaaggag catttccagg aacactttac catcctatct agtcaaactg cctctctgac
    12541 taagactatc acagcagaac aactccaagc cctactcagt atgactcctc tcctctttca
    12601 cgttgaccag agcaagattg actggagcca actgacagag attaccatcg aagcagagat
    12661 tttggttggg aaagcattct aatactcttc aaaccacgtc aacgtcgcct tgccgtacgt
    12721 atggttactg acttcgtcag tttcatctac aacctcaaaa ccatgttttg agctgacttc
    12781 gtcagtttta tctgcaacct caaagctgta ctttgagcaa cctacggcta gtttactctt
    12841 taattttcat tgagtataaa ctagacttcg caaaagtaga aaacttaccg aaaatcttca
    12901 atatgacaaa aacgtataag aacaggtaca caaaccttaa tcttatgcgt tttgttatag
    12961 tttccataca cattaagggg aaatagttga aatcagttct tttaataacc attgaatacc
    13021 atatactaca tttaccccaa atatgatata ggccgtataa atcaagtatt tcgatttttc
    13081 ccgcctcaaa gaatagatct tatacaaaat aaataaattt aaaataataa ataatagaga
    13141 caaaatcttc ctccaaaatc aatcctaaaa gtagccagtc aagcatagct ctaatcttta
    13201 ttttcgattc gatataacaa acttatcaat gaatagtaag tgatataagg ccagtaccag
    13261 accccaaacg ctaccacgaa aagagaattc ttgatgattg agagtaaaca aatcatggtt
    13321 accaatatag aggcaggtca aaataacaaa taaaatccaa aataaatccg tccatttata
    13381 ttttgaaaaa tattttttta acataatagc atattttttt gactataata acagtatatg
    13441 ataaaatgta agcagataca aataaaaagg agaaaagttc atgaacaaat taatgaaatt
    13501 tatttcggtt tttttgacgt caattgtgtt aattgtatca gcgattccaa gtgtttcagc
    13561 tgtatacgct tctgaacaag tatcacaaat tgaaacaaat atggaacttc aacctgtcac
    13621 ttctctaaca gaagaacaaa tcaatacact tgcaaacgaa atccaatctt ttcatccaga
    13681 cgtctcacaa caatggatca aagaagtaat taaccgacaa ttacaaggcg attatacaat
    13741 cccacctaca tactctccat ttagagcagc ttggcaaggt attacagtta atcaaatggg
    13801 tgctctatta gatactgcaa tagctttagc attaggagga actactgcag gccttgcaaa
    13861 tctaattaaa gtaaaaggaa aacatgcagc aaaaagtgct attcgttcag caatttctag
    13921 atatctaggt agttggtttg taaatgatgt tgctttagaa ttcgctatga atttattatc
    13981 accggggact tatttagcac aattatggga taaaaatgat gccattccta acaacagaag
    14041 gattaacttt taatcatgag atatacaata aaattaattg ggtataacgt attttcgttg
    14101 tttatattct ttatcttatc aatgttgttt aaagttccct ttaggtggtg gatcagcatt
    14161 gcaatgacga cttcgtcgta cattgtatat aattacttaa agaaaaagag agaaaaggaa
    14221 tgatcttata ccagatcatt ccttttctgc tttctgtaaa tccctcggag tgtgtttggc
    14281 gctttgatac gaagtgtcaa agctgtataa acgttactat ttccaaaaaa gtaacagaaa
    14341 attcctgctt tgtaggactg ctttgggtga gtaatagaca cgtcgactca ccctatctcc
    14401 tgatggcgaa aagaatttag caatggtgca agttgttctg aactcgagaa aaaacatgcc
    14461 gaaatcgaag aaaagcgtgc agaacttgaa gcgaagaagc aagaaatgtt gaagcgcttg
    14521 gataaataga atttagaaaa cagaaaaaac taaaaagaat gtagggttta tttccctaca
    14581 ttcttaaaat aacttagtac ataaatgaca atgctgccac tgccgtcaat attgcaaaaa
    14641 ctattttcca aattttttta ttttttccaa aaatcttatc aggtaacaag cttattacaa
    14701 gaaaggtaat aaacaacacc aatttaagtg tgtatatcat aaaaacacct tctttcctac
    14761 aattatatta taatacttta tgtaagcgaa tacaagagat atgaggtaac caactacgaa
    14821 aaaatataag gctgaagaca gtaaaaacca gcatttaaag ccttcactgt atctaggatt
    14881 tccctatttt tagacaagat tgacccaaat ccacagcatt taaaaaagcg aatttcaatc
    14941 gaaactcgct tttttacaaa atgtattagt ataaatttgt atcttatact caatgaaaat
    15001 caaagagcaa actaggaagc tagccgcagg ttgctcaaag caccgctttg aggttgcaga
    15061 taaagctgac gtggtttgaa gagattttcg aagagtatta gttcaagtgc cagatgtctt
    15121 cgttatactg agcgattgta cggtcagatg agaagaatcc tgctttagaa atgttaacga
    15181 tgactttatc caaccatgcg tcacggtctt cgtagtcagc aagcatttgc tctttgactt
    15241 tgatgtagtc ttccaagtca agaagagtca tgaaccagtc tttgttgatc aattcattgt
    15301 aaagacgttc caagcgctct ttgtttccag ctgcaagaac tgcatcgcta acaatgaagt
    15361 caaccaatgg tttgatagct tcacgagcgt agaattcgct tgatttatat gctgcttttg
    15421 cgtaaaggtc gataacagtt tctgaatctt caccaaagat gtagatgttt tcgtcaccaa
    15481 ccaactcagc gatttccacg ttagctccgt ccatagtacc aagtgtcaaa gctccgttca
    15541 acatgaattt catgttacca gtacctgaag cttctttaga agcaagtgag atttgttctg
    15601 agatatcaca tgctgggata aggaaacttg ctgcagtaac gttgtagttt tcaaccataa
    15661 ctacttgcaa gtgtggagct actgctggat cgttagcaat aacttctgac atgcaaagga
    15721 ttaaatggat aatgtcttga gcgattgtgt aggctggagc tgctttacca ccaaagaaga
    15781 ttgtgattgg acgagcaggg atgttaccag ctttgatgtc aaggtatttg tggatcacgt
    15841 acaaagcgtt catttgttgg cgtttgtact cgtgaagacg tttgatttgg atatcaaaga
    15901 tagaatttgg attgatttcc acaccttggt gttctttcaa gtgacgagcc aatttacgtt
    15961 tgttgtgagc cttgatgctt tccaattttt ctttgacagc tgctttgtct tcataagaca
    16021 aaagtttttc aagctcatct gcttcatggt gccaaccatc tccaagaatc tcatccaagt
    16081 agtgagacaa tcttgggtta gcatgcataa gccaacgacg gaaagtgata ccgtttgttt
    16141 tgttgttgaa cttttctggg taaaggtcgt agaaggcttt caactcagaa tttttcaaga
    16201 tttcagtatg aagtgctgca accccgttaa cactgtatcc gtagtggata tccatgtgag
    16261 ccatgtgaac acgtccgctc tcatcgatga tttgaacagc tggatctttg tactctgcct
    16321 tcacacgacg gtccaattct tcgatgattg gtaccaagtg aggaaccact tcttgcaaga
    16381 attcaagagg ccatttttca agcgcctcag caaggattgt gtggttagtg taggcagtca
    16441 tgctacgaac aattgagatt gcttcgtcaa gctcgatacc acgtgcagtc aaaagacgaa
    16501 tcaattcagg aatcaccatt gatgggtgag tatcgttgat ttggacaact gcgtagtcag
    16561 caaggtcatg caagttgctt cctttttcga ttgcttcgtc gatgatcaat tgcgcaccgt
    16621 ttgaaaccat gaagtattgt tgaaagatac ggagcaattc accttgacgg tcactatcat
    16681 ctgggtaaag gaagagagtc aagttgcgag cgatatctgt cttgtcaaag ttgataccat
    16741 ctttaataat agaagaatca actgaatcca agtcaaacaa acgcaagcgg tttttagtcg
    16801 ctgtttcata accagtaaca tcaatatcgt aaagagttga tgtcgaagta aagtctgcaa
    16861 atggtacttg gtagctacgg cttgagcgaa ccaaccagtt ttgctctgtc aaccatgcat
    16921 ttggaattgt ttcttgttgg ttgtttttaa gaacttgttg gaaaagacca aagtggtagt
    16981 taagaccaac accgtcacca ttcaaaccaa gagtagcaat tgagtcgata aagcaggcag
    17041 ccaaacgtcc caaaccacca ttaccaagag atggttccaa ttcaacttct tcaacttcga
    17101 tcaagtcttt acctgcagct gcaagttctt ttttaacatc gtcgtaaaga ccaaggttaa
    17161 tcaagttgtt tgacaagagt ttaccaatca agaactcagc tgagatgtag taaacttttt
    17221 tcttaccagt gttgactggt ttttggctgc ttgcaagctt gctgtagtta agaagagcaa
    17281 ggtaaagctc ttcattgcta cattctgcaa tggttttatt gtaacgattt tgtacaaatt
    17341 cttgtagtga taacatgttt agttgtctcc tgattattgt cttatttctt taaatctacc
    17401 aaattttcat taattcggcg ataaattgtt gtcaagtcaa gcaaaccttc ctcgacagct
    17461 ggtgtcaatt gatcttcagt catacgccaa gaccagtttc caccaagggt agatgggaag
    17521 ttcatacgag ctgcctcatc caattctagt aaatcttgca tagttgcaat tgccataaag
    17581 ctaactgatg aaaatactgt acgaagcata gcgtgtacca ctgtttcgta ttctttacgg
    17641 ttcgtgtaac gagccatgta ctcacgagtc gcatcatcaa tctcattacg gtaccaacca
    17701 agaaccgtat tgttatcgtg tgttcctgtg tacataactg agttagcagg tgccaagtgt
    17761 gggctatcaa tgctttcgtc ttctgggttg aaggcaaatt gaagaatctt cattcctggg
    17821 aagccagtac gttcacgtaa ttcgatcact tcatctgtca tgaagccaag gtcttctgcg
    17881 atgatgttta gctcaccaag ttcttcctta acggctgcaa aaagcttgta gcctggacct
    17941 ttcacccact caccaggtgc tgctgtatcg gaaccagcag ggatttccca ataagattcg
    18001 aagccacgga agtggtcgat acgaacgata tcgtagattt tgaagctttc acgcaagcgt
    18061 tcaatccacc atttgtagcc gtctttgtcc attgcttccc agtcatagat tgggttaccc
    18121 caaagctgac cagttacaga aaactcatct ggtgggcatc ctgcgataca agtagcctta
    18181 ccattgacat ctgttttgaa gagatgtgga tttgcccaca tatcacttga atcttccgct
    18241 acgtagattg gcatgtcccc aacgatttca atgtggttgt cgttagcgta agctttcaat
    18301 ttcaaccatt gttggaagaa gaagtattga gtcacacggt ggtaaaccaa cttgtctgcc
    18361 aattgctcac gatagctttc aagtgctgaa gctttacgag cacgagcatc tgcatctggc
    18421 cattcagtcc aagcaagatt gtcaaaatgc tctttgatag ccatatactc agcaaagagc
    18481 tcaagccatg attggttgtc ttgagcaaat ttctcaaaat ctttaacatc tccgacttca
    18541 aagaaacgtt tcaccgcttt ttctaaaaga ggacgacgtg catagtagat tttagcatag
    18601 tcaacttcag acgcatcgct accaaagtca actccttcaa ggtcactcgc tcccaacaaa
    18661 ccttgctcca ccaagatatc taaatcgata aaatgagtgt ttcctgcgaa ggctgagaaa
    18721 gattggtaag gagaatcccc gtaactagtt gctcctaatg gaaggatttg ccagtaacgt
    18781 tgttttgtac ggaccaagaa atcaacgaag tcgtaagcac tttgaccaaa tgatccgatt
    18841 ccgtaagctc ctggaagaga agagatgtgc atcaacacac cactttgacg ttttttcata
    18901 atagcacctc gtgtgttaaa ataatggaac gttgcgtatt ttgcagacgc aaacgtttgc
    18961 gttacttata agtatactcc ttttcaagca taattgcaag cgtttttaaa aaactttttt
    19021 gattattttt aaggagacta actcatttta gcaaagataa cttaaaacta tctaatccta
    19081 aagtttgact ctcacgagac agtctacaaa gtacaaaacc tccttaggga gcttgaattt
    19141 atatgcaaca aagcacaaac gtctatagaa aatagatagg gattagaaac agggaggtag
    19201 cccctcctga tttccctctt tagacagatt ccatatattt ttattaaaaa tactgtattc
    19261 ttatctattt catacttttc ttctatataa aatgcaaaat tatgctatca aatcaagctt
    19321 aaaaattttt taaaattttt acaaaaaata cttgcaaccg ttttctattt gtgctatact
    19381 aagctcataa aggaaaacgt ttgcgtttcc ttatcaataa aacttgctat tctttgggag
    19441 gaatacacta tgtcatctaa atttatgaag agcactgcgg tgcttggaac tgctacactt
    19501 gctagcttgc ttttggtagc ttgcggaagc aaaactgctg ataagcctgc tgattctggt
    19561 tcatctgaag tcaaagaact cactgtatat gtagacgagg gatataagag ctatattgaa
    19621 gaggttgcta aagcttatga aaaagaagct ggagtaaaag tcactcttaa aactggtgat
    19681 gctctaggag gtcttgataa actttctctt gacaaccaat ctggtaatgt ccctgatgtt
    19741 atgatggctc catacgaccg tgtaggtagc cttggttctg acggacaact ttcagaagtg
    19801 aaattgagcg atggtgctaa aacagacgac acaactaaat ctcttgtaac agctgctaat
    19861 ggtaaagttt acggtgctcc tgccgttatc gagtcacttg ttatgtacta caacaaagac
    19921 ttggtgaaag atgctccaaa aacatttgct gacttggaaa accttgctaa agatagcaaa
    19981 tacgcattcg ctggtgaaga tggtaaaact actgccttcc tagctgactg gacaaacttc
    20041 tactatacat atggacttct tgccggtaac ggtgcttacg tctttggcca aaacggtaaa
    20101 gacgctaaag acatcggtct tgcaaacgac ggttctatcg caggtatcaa ctacgctaaa
    20161 tcttggtacg aaaaatggcc taaaggtatg caagatacag aaggtgctgg aaacttaatc
    20221 caaactcaat tccaagaagg taaaacagct gctatcatcg acggaccttg gaaagctcaa
    20281 gcctttaaag atgctaaagt aaactacgga gttgcaacta tcccaactct tccaaatgga
    20341 aaagaatatg ctgcattcgg tggtggtaaa gcttgggtca ttcctcaagc cgttaagaac
    20401 cttgaagctt ctcaaaaatt tgtagacttc cttgttgcaa ctgaacaaca aaaagtatta
    20461 tatgataaga ctaacgaaat cccagctaat actgaggctc gttcatacgc tgaaggtaaa
    20521 aacgatgagt tgacaacagc tgttatcaaa cagttcaaga acactcaacc actgccaaac
    20581 atctctcaaa tgtctgcagt ttgggatcca gcgaaaaata tgctctttga tgctgtaagt
    20641 ggtcaaaaag atgctaaaac agctgctaac gatgctgtaa cattgatcaa agaaacaatc
    20701 aaacaaaaat ttggtgaata aaaaatttgt tcaagggggg tggaaatcaa atcccccttt
    20761 gaatttatca atagagacac aaataattta gctttcttat aaaaaagtag tatcctatga
    20821 aaggagttaa tatggaaaag caacaaccta gtaaagcagc cctgctgtct atcattcctg
    20881 ggttaggaca gatttacaat aaacaaaaag ccaaaggttt tatcttcctt ggtgtaacca
    20941 tcgtatttgt cctttacttc ctagcacttg caacccctga attgagcaac ctcatcactc
    21001 ttggtgacaa accaggtcgt gataattccc tctttatgct gattcgtggt gccttccatc
    21061 taatctttgt aatcgtttat gtactctttt atttctcaaa tatcaaagat gcacatacga
    21121 ttgcaaaacg cattaacaat ggaattccag ttccacgcac actcaaagac atgatcaaag
    21181 ggatttatga aaatggcttc ccttacctct tgatcattcc atcttatgtt gccatgacct
    21241 tcgcgattat cttcccagtt atcgtaacct tgatgatcgc ctttaccaac tacgacttcc
    21301 aacacttgcc accaaacaag ttgttggact gggttggttt gaccaacttt acaaacattt
    21361 ggagcttgag taccttccgt tctgcctttg gttctgttct ttcttggact atcatttggg
    21421 ctttggcagc ttctacttta caaatcgtaa ttggtatctt cacagctatc attgccaacc
    21481 aaccatttat caaaggaaaa cgtatctttg gtgttatttt ccttcttcct tgggctgtcc
    21541 cagccttcat cactatcttg acattctcaa acatgtttaa cgatagtgtc ggtgctatca
    21601 acactcaagt attgccaatc ttggctaaat tccttccttt ccttgatgga gctcttattc
    21661 cttggaaaac agacccaact tggactaaga ttgccttgat tatgatgcaa ggttggctcg
    21721 gattcccata catctacgtt ttgactttgg gtatcttgca atctattcct aacgaccttt
    21781 acgaagcagc ttatattgac ggtgccaacg cttggcaaaa attccgcaac atcactttcc
    21841 caatgatttt ggctgttgcg gcacctactt tgattagcca atacaccttc aactttaaca
    21901 acttctctat catgtacctc ttcaatggtg gaggacctgg tagtgtcgga ggtggagctg
    21961 gttcaaccga tatcttgatc tcatggatct accgtttgac aacaggtaca tctcctcaat
    22021 actcaatggc ggcagctgtt accttgatta tctctatcat tgtcatctca atctctatga
    22081 tcgcattcaa gaaactacac gcatttgata tggaggacgt ctaagatgaa taactcaatt
    22141 aaactcaaac gtagactgac tcaaagcctt acttaccttt acctgattgg tctatcaatt
    22201 gtaattatct atccactgtt gattaccatt atgtcagcct ttaaagcagg taacgtctca
    22261 gcctttaaac tagatactaa tatcgacctc aattttgata actttaaagg cctcttcact
    22321 gaaaccttgt acggtacttg gtacctcaac actttgatta tcgccttaat taccatggct
    22381 gttcaaacaa gtatcatcgt acttgctggt tatgcttaca gccgttacaa cttcttggct
    22441 cgtaaacaaa gtttggtctt cttcttgatc atccaaatgg tgccaactat ggccgctttg
    22501 acagccttct tcgttatggc gcttatgttg aacgccctta accacaactg gttcctcatc
    22561 ttcctctacg ttggtggtgg tatcccgatg aatgcttggc tcatgaaagg ctacttcgat
    22621 acagtgccaa tgtctttaga cgaatctgca aaactagacg gtgcaggaca cttccgccgc
    22681 ttctggcaaa ttgttctacc acttgttcgc ccaatggttg ccgtacaagc tctctgggcc
    22741 ttcatgggac ctttcgggga ctacatcctc tctagtttct tgcttcgtga gaaagaatac
    22801 tttactgttg ccgtaggtct ccaaaccttc gttaacaatg cgaaaaactt gaagattgcc
    22861 tacttctcag caggtgctat cctcatcgcc cttccaatct gtattctctt cttcttccta
    22921 caaaagaact ttgtttcagg acttacaagt ggtggcgaca agggataatt tatccccgcc
    22981 accctttttc attttatact cttcgaaaat ctcttcaaac cacgtcagct ttatctccaa
    23041 cctcaaagtt gtgctttgag caacctgtgg ctagtttgca ctttgatttt cattgattat
    23101 tagcaattgt cactgtaaat aatatccttg tagcaagcaa tttttctcct agacttgaaa
    23161 taaagcgcat ttctctatat aataatactc atatagaaaa caccttttag aaagatacct
    23221 atgcttccat atccattttc ctatttttca agtatttggg ggtttcgtaa gcccctgtcc
    23281 aaacgtttcg agctcaactg gtttcaactt ctctttacca gtatcttcct tatcagcttg
    23341 tctatggtac ccattgctat ccaaaacagc tcccaggaga cctatccgct agaaactttt
    23401 atcgataatg tctatgaacc tctgacaaat gaggttgtcc aggatctctc tgaacatgct
    23461 acaattgtcg atggcacatt aacttatact ggaacagcta gtcaaacccc ttctgttgtg
    23521 attggtccaa gtcaaatcaa ggaattacct aaggacttgc aactgcattt cgatacaaat
    23581 gagctagtca tcagcaagga aagcaaggag ctgacccgca tctcttaccg agccattcag
    23641 actgagagtt tcaaaagcaa agacagcttg acccaagcaa tttctaaaga ctggtaccaa
    23701 caaaatcgtg tctatatcag cctcttccta gttctcggtg cgagcttcct ctttggtttg
    23761 aatttcttta tcgtctctct aggagctagt cttctccttt atatcactaa gaaatcacgc
    23821 ctcttttcat ttagaacctt taaagagtgc tatcacttta tcttgaactg tttaggattg
    23881 ccgactctga ttacacttat tttgggatta tttggccaaa atatgacaac cctgattact
    23941 gtacaaaata ttctttttgt tctgtatctg gtcactatct tttataaaac acatttccgt
    24001 gatccaaatt accataaata ggagattttt atgcccgtta cgattaaaga cgtggccaag
    24061 gctgctggtg tttcgccttc aaccgtaacc cgtgttattc aaaataaatc aaccattagc
    24121 gacgaaacaa aaaaacgcgt tcgcaaagct atgaaggaac tcaactacca cccaaacctc
    24181 aacgctcgta gcttggtaag cagctatact caggttatcg gattagttct tcctgatgac
    24241 tcagacgcct tctaccagaa tcctttcttt ccatcggttc tacgtggcat ctctcaagtc
    24301 gcatctgaaa accactatgc cattcagata gcaacaggga aagatgagaa ggagcgtctc
    24361 aacgctattt cacaaatggt ctacggcaag cgtgtagatg ggctaatctt tctctatgcc
    24421 caagaagaag accctctcgt aaaactcgtc gcagaagaac agttcccctt ccttatctta
    24481 ggtaaatctc tatctccttt catcccactt gtcgacaacg gcaatgttca agctggtttt
    24541 gatgcgactg aatatttcat caaaaaaggc tgcaaacgca ttgcctttat cggaggaagt
    24601 aaaaagctct tcgtgaccaa agaccgttta acaggctatg aacaggcgct taaacattac
    24661 aaacttacca ctgacaacaa tcgcatctac tttgccgacg agtttctgga agaaaagggc
    24721 tataaattta gcaagcgatt attcaagcac gatccacaaa ttgatgctat catcacaacc
    24781 gatagcctcc tagctgaagg tgtttgtaac tatattgcca aacaccagct ggatgtccct
    24841 gttctcagct ttgactcggt taatcccaag ctcaacttgg cagcctatgt cgatatcaat
    24901 agtttagagc ttggtcgtgt ttcccttgaa actattctcc agattattaa tgataataaa
    24961 aacaataaac aaatttgtta ccgtcaattg atcgcccaca aaattatcga aaaataagag
    25021 actgggcaaa aagtcgttaa aagcaaaaac gcatactatc aggtattgaa aaaacttgat
    25081 actatgcgtt ttaatgtggg aagatttact tccttttcta ctgaaattga gtcttttccc
    25141 aagatctttt tatactcaat gaaaatcaaa gtgcaaacta ggaagctagc cgcaggttgc
    25201 tcaaaacact gttttgaggt tgtagatgaa actgacgaag tcagctcaaa acatggtttt
    25261 gaggttgtag atgaaactga cgaagtcagt aaccatacct acggcaaggt gaagctgacg
    25321 tggtttgaag agattttcga agagtattaa tcactaatta tctatctcaa caaatcttcc
    25381 tagaatatga acattttccg agacagagac aaaggagctt ggatccactt gtgtcataat
    25441 ctgtttaaat tcattaaact ctgcacgtgt aatgacagtg attaaaactg cctttctctc
    25501 gtgattatag gttccttctg catcgtggat catggttgct ccgcggtgca attttttatg
    25561 gattttttca attaccttct ctggatgatt tgtcacaatc atggcctgca tacgcttttg
    25621 cttagtaaag actgcgtctg tcacacggct agagacaaag atggtaatca tagaataaag
    25681 agcgtatttc caaccaaagg ttaaacctgc tatcagcatg atagttccat ttaccaagaa
    25741 agaaatacta ccgacattct tacccgtttt cttgcgaata gtcaggctga cgatatccgt
    25801 cccaccactg gagatattgt ttcgaagagc aaaaccaatc cccaaaccca taacaacacc
    25861 cccaaaaagg gaattgataa tgggatcctc cgtcaaggtt gccacaggga caaactggat
    25921 aaagaaggaa ctcatagata ccgtgataaa ggtaaagacg gtgaacttat ggccaatctg
    25981 ataccaagct aagaccatca aagggaagtt aatggcgtag aagcttagcg aaatcggaat
    26041 atgaaaacca aaccagtgat tactcaaggc agagataatc tgtgccagac ctgttgcacc
    26101 actcgaatac acatgccctg gttggaaaaa gaaattaact gctactgctg ataaaaaacc
    26161 atagaccaga gaggccgaaa tcttctcatc atacttttct cgagagatac tttgtaagac
    26221 acgtaaaatt tttatctgat aagcaaagcg gcgcagataa tagcgccacc gcttaattcg
    26281 ttttgcttgt ttcatcttct tctacttgta agctgagttc ctctagttgt ttgagagcga
    26341 ctgttgatgg agcttgtgtc attgggtcag ttgccttgtt gttcttagga aaggcaatga
    26401 cttcacggat attttcttct ccagcaagca acatgacaaa acggtcaagc ccgatagcca
    26461 aaccaccgtg tggtgggaaa ccatagtcca tggcttcaag aaggaaacca aactggtcat
    26521 tggcttcttc agttgagaaa ccaagagcct tgaacatgcg ttcttgaagg tctttttggt
    26581 tgatacgaag gctaccacca ccaagctcat aaccgttcaa gacgatatca taagcaatgg
    26641 cacgaacctt agccaaatca ccttctaatt cgtgagcagt ctcttcctgt ggaagggtga
    26701 aaggatggtg ggcgctcatg tagcggcctt cttcttcaga ccattcaaac atcggccagt
    26761 caaccaccca aaggaagttg aacttatcat tatcaatcaa gccaagctct ttagcaatac
    26821 gtccacgaag ggcacccagt gttgcattag ccacttcaag cgtatccgcc acaaagagaa
    26881 ccaagtcctt atcttcaaga acaagcgctg ttgtcaattc ttcttggata ccagtcaaga
    26941 acttggcaac tggtccgttt aattctccat caaccacctt gacccaagca agacctttgg
    27001 caccatactg tttggctact tccgtcatct tgtcgatgtc tttacgtgaa tagttgtccg
    27061 cagctcctgt gaccacaatc gcttttacag caggtgcttc tgaaaagact ttaaagtcta
    27121 cacctcggac cacttctgtc aagtcctgaa gcaacatgtc aaaacgagta tctggcttgt
    27181 cagaaccgta aagagccata gcatcatcgt atttcatacg agggaatggt agcgttactt
    27241 cgatgccttt tgtttccttc atcacgcgcg cgatcaagcc ttctgtaata tcttggattt
    27301 cttgctcagt aaggaaggac gtttccaagt cgacctgagt aaattcaggc tggcggtctc
    27361 cacgcaagtc ctcgtcacgg aaacatttaa cgatttggta gtaacggtca aaaccagcat
    27421 tcatcaagag ctgtttcgtg atttgtggac tttgaggaag agcgtaaaaa tgccccttat
    27481 taacacgaga cggcactaaa taatcacgcg ccccttcagg cgttgactta gaaaggaatg
    27541 gtgtctccac gtcgataaac tccaactcat ccaagtagtt gcggatagag tgggtcacct
    27601 tggcacgaag tttaagattt tccaacattt ctggacgacg aaggtcaagg taacggtaac
    27661 gcaaacgtgt atcgtcattt gcctcaatgc catccttaat ctcaaatggt gttgtcttag
    27721 ctgtgttaag cacaataaga gctgtcacgt ttaactcaac cgcaccagtt ggcaacttat
    27781 cattggcttg ctcacgcgca gcgacctgac cagtcacctc aataacaaat tcgctacgaa
    27841 ggctttcagc tgttgccata acctctgcag atactttttc agggttgata accaactgca
    27901 tgattccttc acggtcacga agatcgataa agatcaaacc accaaggtca cgacgacggc
    27961 caacccatcc tttcaaggtt atttcttgtc cgatgtgttc ctcacgaaca cgaccagcat
    28021 acatactacg tttcattatt tctctcctct tttattctgt tactatttta ccataaaagc
    28081 gcaggctctt catgaaaatc atcagaaaag tttgccagtc tttaaaagtc aggtgaaagc
    28141 cctaaaaatt agcgctaata ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta
    28201 ccgtagtacg gttactgact tcgtcagttt catctacaat ctcaaaacca tgttttgagc
    28261 tgacttcgtc agtttcatcc acaacctcaa aacagtgttt tgagcaacct gcggctagct
    28321 tcctagtttg ctctttgatt ttcattgagt ataatacaaa aatccgatga acttcaccgg
    28381 actcttttat tttgaatttt tgcctgcttt acgcttttca gcgatttcgg ctgcctttcg
    28441 aggcaagaca atttccgtta tgtaagccgt cccaaaacgc agtacacctg caataggagc
    28501 aaagacaact gctagatagt tatagaagaa atcgcctttg aaggcataag ctagcgctcc
    28561 aatgatgaaa aatagaacga ctgcctgaat cactgccaat aaaattactc gtttcatgtg
    28621 acctcctgac tctattatag catgagaatc atcaaaaagc cgactaaatt attcaaagcg
    28681 tgaagagaaa tactgtagac cagacctttt ctgctaatgt aagccaaacc caaactaaaa
    28741 ccaaggctaa aatagacaaa aaattgttgc acatcacctg gaaaatgaat caaggcaaat
    28801 agaagactag ataccagaag aaaaatcagg gttcgtttac tattgtcctg cttaggaaag
    28861 agatagcgtg ctaacatccc tctaaaaaca atctcttccg tcaaaggagc aaaaataacc
    28921 acagcaaaga atgagaaaag tggttgagac aaggtcaagt ctgtcgctat ttgctgattt
    28981 actgaaggat catctggcaa gaagaattga acgaccagag ataagaacca aaccaagaca
    29041 ggaagccaaa taaatcgatt aaagccgctc ttctcaatat gaacaggagc cttctgatac
    29101 catttgtaaa tgccgtacac atatactcca gccaaggcca catagagtag agtaacagca
    29161 tagggtgaag cgcctaaagc aagcgacgca gtcgcgagcc cctgaataaa gccatagata
    29221 aataaaaagg atagaagggc tagaagaatc cagccaaggt ttttaagtaa tttcatagat
    29281 aactccttta tttgaaataa cgttttacca taggtaactg catcacattg atataaacat
    29341 ggatggctcc tacaagcaag aaagctagta actgaatctc tcctgtcaag aaagaaatga
    29401 taataagaaa aatatataag gctggtaaga catattggtg taattggaat aaaattcgaa
    29461 aactctgttc caaattagcc tgacgctccc cttcatcata agaatttata tagttcaaga
    29521 catcctttgg tgtagcgaaa aattccaaat caaactgacg aacaatcgca atggttttaa
    29581 aaagagattt ttgagcgact aagaatacca caaagagtaa gaaagaaagg aaaaatgttt
    29641 gagggtttgt atgcaatata atcacctcac ttaatgaaat aaaaatagcc aatggaatcg
    29701 ctacacctgt aatattaaaa gcaatggttc caaactcaag attccgatac atttgcacat
    29761 aataggtttc attcagatcg tcatccattt cctcttgata caaggaatga aattttctgc
    29821 ttttctttaa gaaattgaaa gtcaaaaaca tactaatgaa acctatcagt aaacaaatag
    29881 ctgatatcca tggcatcaag gcttttacat ctaaaataat ttcgtgggat tcgacacgtg
    29941 ccttaaacat ccctacaaac atgcccaaga accccccaag acaatagaca tcaaaaataa
    30001 caatctacgt ttctttttca tattcattct cctttttcac ttgctagatt tttggatttc
    30061 ttttcaatcc attcaattac tgggatgaga gcaaagtaga cccaaacaaa ttggtcgctt
    30121 tgatagggat taaaccagct taggtccatc ccaatcagta gaaatacgct gactaataaa
    30181 gctatgacca ctacataata aatcacttta tacttgttca tcactcgtcc tcctccaaac
    30241 gaaataccga ttcgactgtt tcgttgaaaa tttgagatat tttcagggca atgataatgg
    30301 atggggtgta ctcatcccgt tctagtaggc taatggtctg tctggaaacc cctgccagtt
    30361 tggctaggtc ggtttgattg agaccatcgc gagctcgaag ctcttttaga cgatttttta
    30421 gttgcacgtt acacacctac tctccgtcaa attcaacggt ttggatatct tcaatacgtt
    30481 gcaacttgaa tttttctttt cccgtattat ctacacgtcg tagctttacc cattcctcat
    30541 caacatccac aacttcccag ttatctggcc caatatacac tcccgttata attggttcct
    30601 ttccaatcat ttcttgtaat aatctcgaca tttctgcgtt tcctttctct tttcgctcaa
    30661 gtcttttgat tttattctct agtttcttga tttttttaga attattagaa taaaagaaaa
//
LOCUS       DAVLGK010000024        30667 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLGK010000024 DAVLGK010000000
VERSION     DAVLGK010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.024"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            182..835
                     /locus_tag="VXE01_001208"
     CDS             182..835
                     /locus_tag="VXE01_001208"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV0750112.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            845..1309
                     /locus_tag="VXE01_001209"
     CDS             845..1309
                     /locus_tag="VXE01_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0750113.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1322..2590
                     /locus_tag="VXE01_001210"
     CDS             1322..2590
                     /locus_tag="VXE01_001210"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV0750114.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2604..2864
                     /locus_tag="VXE01_001211"
     CDS             2604..2864
                     /locus_tag="VXE01_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750115.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2875..4236
                     /gene="pdrM"
                     /locus_tag="VXE01_001212"
     CDS             2875..4236
                     /gene="pdrM"
                     /locus_tag="VXE01_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV0750116.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKPKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            4390..5358
                     /locus_tag="VXE01_001213"
     CDS             4390..5358
                     /locus_tag="VXE01_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV0750117.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5374..6366
                     /locus_tag="VXE01_001214"
     CDS             5374..6366
                     /locus_tag="VXE01_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV0750118.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6584..7627
                     /locus_tag="VXE01_001215"
     CDS             6584..7627
                     /locus_tag="VXE01_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV0750119.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVITQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7691..9376
                     /gene="lpdA"
                     /locus_tag="VXE01_001216"
     CDS             7691..9376
                     /gene="lpdA"
                     /locus_tag="VXE01_001216"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV0750120.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKGDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9440..10429
                     /locus_tag="VXE01_001217"
     CDS             9440..10429
                     /locus_tag="VXE01_001217"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV0750121.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLTQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10502..11572)
                     /gene="xerS"
                     /locus_tag="VXE01_001218"
     CDS             complement(10502..11572)
                     /gene="xerS"
                     /locus_tag="VXE01_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV0750122.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKIMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(12147..13697)
                     /locus_tag="VXE01_001219"
     CDS             complement(12147..13697)
                     /locus_tag="VXE01_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV0750123.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMSDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQILGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVRNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13713..14492)
                     /locus_tag="VXE01_001220"
     CDS             complement(13713..14492)
                     /locus_tag="VXE01_001220"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV0750124.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(14479..15330)
                     /gene="ylqF"
                     /locus_tag="VXE01_001221"
     CDS             complement(14479..15330)
                     /gene="ylqF"
                     /locus_tag="VXE01_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV0750125.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15523..15726)
                     /locus_tag="VXE01_001222"
     CDS             complement(15523..15726)
                     /locus_tag="VXE01_001222"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0750126.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVRNSFLLPLKSHHLMAFFYIG"
     gene            complement(15778..21669)
                     /gene="iga"
                     /locus_tag="VXE01_001223"
     CDS             complement(15778..21669)
                     /gene="iga"
                     /locus_tag="VXE01_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HEV0750127.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLTEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDSYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     SPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPAVKLTELY
                     LEEQFSKTKQNLGGSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     HHGTTDLFSALETYRKVFLPNTSNNDWFKKQTKAFIVEEKSTIAEVKAKQKQAGTKYS
                     IGVYDRITSNTWKYRNMVLPLLTLPERSVFVISTLSSLGFGAYDRYRNSEHKAGKDLN
                     NFVEENASETAKRQRDHYDYWYRILDNEGREKLYRTILLYDAYKFGDDTTSGKATVEA
                     KFDSSNPAMKNFFGPVGNKVVHNHHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPYDATITINSILKHSKSDSLEGSRLQVL
                     DPTERFQNSADLQNYVHNMFDLIYMLEYLEGQSIVKKLNVSQKMEALRKIENQYLTDP
                     ADGNEVYATNVVKELTEEEARNLNSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAP
                     IFSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEGIAKQNGQTINLYGK
                     KQGLVTDKLVLEKIFSGKYPSWTAFKKAMYQERIAQFDHLTKVIFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYNPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            complement(21878..23056)
                     /locus_tag="VXE01_001224"
     CDS             complement(21878..23056)
                     /locus_tag="VXE01_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750128.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSFIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSNFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(23271..26921)
                     /gene="addA"
                     /locus_tag="VXE01_001225"
     CDS             complement(23271..26921)
                     /gene="addA"
                     /locus_tag="VXE01_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV0750129.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGIEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIDSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEAYRQCKRQENAFEFTDIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMNILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWVISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFLTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(26918..30193)
                     /gene="rexB"
                     /locus_tag="VXE01_001226"
     CDS             complement(26918..30193)
                     /gene="rexB"
                     /locus_tag="VXE01_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV0750130.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LEILFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLEQQGLENPAIPTSPSSKTLAKDTLQALY
                     PDKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(30393..30548)
                     /locus_tag="VXE01_001227"
                     /pseudo
     CDS             complement(30393..30548)
                     /locus_tag="VXE01_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         8643 a         6105 c         6335 g         9584 t
ORIGIN      
        1 gtagtaaaat gcttaatgat ttaaaaagta attataaaaa atagccagtc tttataaact
       61 gtattcacgt attcaaatcg tatatatagt cgatttatta aatctttaga taaactgtaa
      121 aaagtggttt ccatagccac tttttgctat aatagaggca gtaaaaatga aggagtcggc
      181 tatggaacac tcgtcttggc atgctttgat taaggcgcaa ttacctgagg gttatttcgg
      241 gaaaatcaat cagtttatgg agcaggtcta ttctcagggg attatttatc cacccaagga
      301 aaaggttttt caggctctct tgacaacact gcttgaagaa gttaaggtgg taattctagg
      361 gcaagacccc tatcacggac caggtcaagc gcagggcttg agtttttctg tacctgactc
      421 tatcccagct ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg atatcggagt
      481 taagaaatct catgatttga cagcttgggc tgagcaagga gtcttgcttc ttaatgcttg
      541 tttgactgtt cctgctggac aggccaatgg tcatgctggt caaatctggg agccttttac
      601 tgatgctgtg attcaggtgg tcaatcatct agatagacca gtcgtttttg tactctgggg
      661 agcttatgca cgtaagaaga aggcattagt taccaatcct catcacttga ttatcgaatc
      721 agcccatcca agtcctttgt cggtttatag aggattttgg ggttccaagc ccttttccaa
      781 ggccaatgca ttcttaaaag agacaggaca agagccaatc gattggctta gataaggaga
      841 aaatatgcct cagttagcga cgatttgcta cattgataat gggaaagaac tgctcatgct
      901 ccatcgtaat aagaaaccca atgatgtcca tgaagggaaa tggattggtg tgggtggtaa
      961 gctagagaga ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg aagaaacagg
     1021 gctcaaagcc aagccagttc taaaaggtgt catcactttt cctgaattta caccagattt
     1081 agactggtac acctatgttt ttaaggtgac ggagtttgag ggcgacttga ttgactgcaa
     1141 tgaggggacg ctagaatggg ttccctatga cgaggttttg agcaagccga cttgggaagg
     1201 tgaccacacc tttgttgagt ggcttttaga ggataaaccc ttcttttcag ccaagtttgt
     1261 ttatgatggg gataaattgt tggataccca agttgatttc tatgaataaa ggagaaagca
     1321 gatgctacta atcaaaaatg gtcgtgtaat ggatcctaag tctggtttgg atcaagtttg
     1381 tgatgtctta gttcaagatg ggaaaattat caaaattgcg cctgagatca cggaagaagg
     1441 agcagaaacg attgatgcta ctggtcttgt ggttgctcct ggtttggtcg atattcatgt
     1501 gcatttccgt gaacctggtc aaacacataa agaagacatt catactggtg ccctggcagc
     1561 cgctgcaggt ggttttacta ctgtcgtcat gatggctaat accagtccaa ccatttcaga
     1621 tgtggagact ttgcaagcag ttctccagtc agctgccaaa gagaagatta atgtcaagac
     1681 agttgcgacc attactaaaa actttaatgg taaaaacttg actgacttta aggcgctctt
     1741 agaagctggt gcggttggtt tctctgatga cggtattccg cttgagagca gtaagattgt
     1801 caaggaagcc atggaggaag ccaaaaaact caataccttt atcagccttc atgaggaaga
     1861 tccaggtttg aacggtgttc ttggctttaa tgaaaatatt gctagagaac atttccatat
     1921 ctgcggtgct actggggtgg ctgagtacgc tatgatggcg cgtgatgtca tgattgccta
     1981 tgcaactaaa gcccatgttc acatccagca tttgtctaag gaagaaagtg ttaaagtagt
     2041 ggagtttgct caggggttag gtgcagaagt cacagcagaa gtagcgccac agcatttctc
     2101 taagacagaa gcacttcttt taacacaagg tagcaatgct aagatgaatc caccgcttcg
     2161 tttggaatca gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca tcacagttat
     2221 tgcgactgac cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata ttaccaaagc
     2281 gccatctggt atgactggct tagaaacatc cctgtctctc ggcttgacct atttagtaga
     2341 agctggtgag ttgagcttga tggaattact tgaaaaaatg acatacaacc cagccaagct
     2401 ttacaacttt gaagcaggtt acttggctga gaatggtcca gcagatatca ctatttttga
     2461 tgccaaggct gaccgccttg tggactccca ttttgcttcc aaagcagcta attcaccatt
     2521 catcggtgaa accttaaaag ggcaggttaa atataccatc tgtaagggac aaatcgtcta
     2581 tcaagcttga taggagttag aatatgaatt attttcgaaa acgtagggag aggcaagcga
     2641 aatctaatag tggaatttac tgtcccgcag ctaatcgttc caaaattcaa tatgaaacta
     2701 aagaaaaagc tgaccatgcg gttcaatatg ataacggagg tttagttaga agctattatt
     2761 gtcgtacatg tgcgtgttgg catactactt caaaatctaa taaacctccg ctaagtttga
     2821 aaaactatgg tctgaaactc tttggtttag ataaatcaga atagaaagag aagtatgtat
     2881 aagacaaagt gtttacgaga gaagttagta ttatttttaa aaattttctt cccaatcctg
     2941 atttaccaat ttgccaatta ttctgcctct tttgttgata ctgcaatgac aggtcaatac
     3001 aacactatgg acttggctgg tgtatctatg gcaaccagta tctggaatcc tttctttaca
     3061 tttctaacag ggattgtgtc agccttggtg cctatcattg gtcaccatct tggtcgagga
     3121 aaaaaggaag aagttgcgtc tgatttttac caatttattt atttggcctt gggcctatct
     3181 gtggtattgc tggggatggt acttttcttg gcaccaacaa tcttgaatca tattgggtta
     3241 gaagcagcag tagcggcagt agcggttcgc tatctttggt ttttatctat cgggattatc
     3301 cccttgttgc tctttagcgt cattcgttcc ttgctggatt cgctgggctt gaccaaactg
     3361 tccatgtacc tcatgctttt gttactccct ctcaatagcg gatttaacta tctcttgatt
     3421 tacggtgcct ttggtgttcc agaactggga ggggctggtg ctggtttagg aacatccttg
     3481 gcctactggg tcttgcttgg gatttctgtt ctggttttat ttaaacagga gaagcccaaa
     3541 gccttacacc ttgagaaacg aattccactt aatatggata aaattaagga aggagttcgt
     3601 ttaggtctgc ctattggggg aactgtcttc gcggaagtgg ctatcttttc agtggttggc
     3661 ttgattatgg ctaagttttc gtccttgatt atagctagtc accagtcagc tatgaacttt
     3721 tcaagtctta tgtacgcctt tcctatgagt atctcatcgg ctatggctat tgtcgtttcc
     3781 tatgaagtgg gagccaagcg atttgatgat gcgaaaacct atattggtct aggaagatgg
     3841 actgccctca tttttgcggc cttcacctta accttccttt acatttttag gggaaatgtg
     3901 gccagtcttt atggtaacga cccaaaattt atcgatttga cagtgcgttt tttaacttat
     3961 agtcttttct tccagttagc agataccttt gcggcgccgc ttcagggaat tttgcggggg
     4021 tataaggata cagttattcc tttttacctt ggtttgcttg gttattgggg cgtagcaatc
     4081 cctgtggcta cgctatttga ttctctaaca gattttggag cttattctta ctggatcggc
     4141 ttgattatta gtttgattgt gagtggggcg ctctaccgtt ggcgtttaac tgtgattatg
     4201 aagagatttg aatctttagc aaaatccaaa tgctaaaaag tttgtgaaaa aatattcttg
     4261 acaagaaaat cccttgtttt cacggggttt tcttttttat tttgtgaaat ttcttttaga
     4321 aaaactttga cagtatttgc caaaagcggt aaaatagtaa ggtaagaaga aagttagaaa
     4381 ggcaagaaga tgtcaacttt agataaaaat cttttgctag aaatgttccg taagatggaa
     4441 gaaatccgtc gcatggactt aaaaattgca caattagtaa agaaagggaa agtgccagga
     4501 atgacgcact tttctgttgg tgaagaggca gctaacgtgg gggctatgtt agctctcaat
     4561 ccagatgatc tgattacctc aaaccaccgt ggacacgggc aagctattgc taaagggatt
     4621 gacctcaacg gaatgatggc tgaaatcctt ggtaaataca ctggaacctg taaagggaaa
     4681 ggtggatcta tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa tggtattgta
     4741 ggtggtggta tggggatcgc tgtcggtgca gccctcagtc agcaaatgca aaataccggt
     4801 aaaatcgttg tctgcttctt tggagatggt gcgaccaatg aaggtgtttt ccacgaagca
     4861 gtgaacatgg cttctatctg gaacctgcca gtcattttct attgcattaa caacggttac
     4921 ggtatctctg cggatatcaa gaaaatgacc aatatagaac atatccatca acgtagcgcc
     4981 gcttatggaa ttcctggaat gttcatcgaa gatggtaaca atgtcatcga tgtctatgaa
     5041 ggatttcaga aagctgtgga ccatgttcgc agtggcaatg gtccagtctt gattgaaagt
     5101 gtaacttatc gctggctcgg tcactcatca tctgaccctg gtaaatatcg tacgcgtgaa
     5161 gaagtggaat tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta ccttattgaa
     5221 aataacattg caagtgccga agaattggaa gaaatccaag cgcaagtaaa ggaagcagta
     5281 gaagcttctg ttaaatttgc agaggaaagc ccattcccac cgcttgaatc agcctttgaa
     5341 gatatttacg cagactaagg agaaagagat aaaatggaaa caaaaacaat gtccttccgt
     5401 gacaccatta tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt gttcttgatg
     5461 ggagaagacg tcggtgtctt cggaggagac ttcggtactt ctgttggaat gcttgaagaa
     5521 tttggtccag aacgcgtccg tgactgtccg atttctgaag ctgccatctc tggagcagca
     5581 gcaggagcag ccatgacagg acttcgtcca atcgtcgata tgaccttcat ggacttctct
     5641 gttattgcca tggacaatat cgtcaaccaa gctgctaaaa cacgttacat gtttggtggt
     5701 aaaggtcagg ttccaatgac tgttcgttgt gcagctggta acggagttgg ctctgccgcc
     5761 cagcactcac aatctctaga gtcttggttt actcacattc caggacttaa ggttgtggca
     5821 cctggaacac ctgcggacat gaaaggcctg cttaagtctt ctatccgtga taaaaaccca
     5881 gttattatac ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc agttgatcca
     5941 gactacacaa ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga tgtaacagtt
     6001 gttacttatg gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt agcagaagaa
     6061 ggaatttcag ttgaaattgt tgacccacgt acccttgttc cgcttgataa ggatatcatc
     6121 ataaactcag tgaagaagac tggtaaggtt gttctggtca acgatgccca caaaacaagt
     6181 ggctatatcg gtgaaatttc agctattatt tcagaatcag aagcatttga ctatctagat
     6241 gcaccaattc gccgttgtgc aggagaagat gtgccgatgc cttatgcaca aaacctagaa
     6301 aatgcaatga ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac ttataacaaa
     6361 gaatagagtt acataagata agttatgtaa ataaaataaa gctgacgaga aactttgtat
     6421 cttttaggtg cagagctctt cgtcattaat atcttagatt agagcacggg ctaaaagctc
     6481 ggaaaaaaga taaatctcct tggcttcatc gaagccatcg tcgatttcct atttttcagt
     6541 cgcttttgac gccctttgta tcataaatag aattggagag gtcatggctg atgacaagct
     6601 aagagcgact cctgcagcta gaaagttagc ggatgattta gggataaacc tctacgacgt
     6661 ttctggctca ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt ataaagacac
     6721 aaacgtggtt cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata acattgcttg
     6781 gcaggaaatc caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg ttttggccct
     6841 gcttcctgaa aatatcgaaa acgatagcat caaatctcct gctcagattg aaaaagtgga
     6901 agaagtccct gataacgtaa caccatatgg tgaaatcgag cgtattccaa tgacacccat
     6961 gcgtaaggtt attacccaac gcatggttga atcttacttg actgcgccaa ccttcaccct
     7021 aaactatgaa gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc ttgagccaat
     7081 catggaagca actgggaaga agactactgt aacagacctt ctttcacttg cagttgttaa
     7141 gactcttatg aaacacccat acatcaacgc ttcattgaca gaagatggca agactattat
     7201 cactcacaac tatgtcaatc ttgccatggc agttgggatg gataatggat tgatgacacc
     7261 tgttgtttac aatgctgaga agatgagtct ttcagaactg gttgtagcct ttaaggatgt
     7321 tattggtcgt accttggatg gtaaattggc tccaagtgag ttacaaaatt caacattcac
     7381 aatcagtaat ttgggaatgt ttggtgttca gtcctttggt ccgattatta accaacccaa
     7441 ctcagctatc cttggtgtca gttcgacaat cgagaagcca gttgtcgtca atggtgaaat
     7501 tgtgattcgc ccaatcatga gtttaggatt aaccattgac caccgtgtcg tagatggtat
     7561 ggctggtgct aagtttatga aggacttgaa agagttgatt gaaacgccaa tctcaatgtt
     7621 aatttaagag caagagtatt catttttaag atatagataa aggaaggaag acatggcctt
     7681 agaagtaatt atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg tccaatggaa
     7741 taaaaaagtc ggagaatttg taaaagaagg agaaatcctt ttggaaatca tgactgataa
     7801 agtcagcatg gaattggaag ccgaagaaga tgggtacttg attgccattc tcaaaggaga
     7861 tggtgaaact gtccctgtaa cggaagttat cggttacctt ggtgaagaaa gggaaaacat
     7921 cccaacagct ggagcagcat cgccagaagc tagccctgta cctgtagcaa gtacctcaaa
     7981 cgatgatggt aagagcgatg atgcttttga tatcgttgtg attggtggag gtcctgctgg
     8041 ttatgttgca gccattaaag ctgcccaact cggcggtaag gttgcccttg ttgagaaatc
     8101 tgaacttggt ggaacctgct taaaccgtgg atgtattcca accaagacct accttcataa
     8161 cgctgaaatt attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga ttgaaaatcc
     8221 taacttcact gttgatatgg aaaaactttt agaaactaaa tctaaagttg ttaatactct
     8281 tgttggtggt gttgcaggac ttcttcgtag ctacggagtt actgttcata aaggaattgg
     8341 tacaatcact aaagacaaga acgtcttggt aaatggttct gaattgcttg aaaccaagaa
     8401 aatcattctt gctggtggtt caaaagtcag caagatcaac gtccctggta tggaatctcc
     8461 acttgtcatg actagtgatg acattcttga aatgaacgaa gtgccagaaa gccttgttat
     8521 catcggtggt ggagttgtcg gtatcgaact cggtcaggcc ttcatgacgt ttggttcaaa
     8581 agtgactgtt atcgaaatga tggaccgtat agttccagct atggatgcgg aagtttctaa
     8641 gaaccttcgc ttgatccttg agcgtaaagg aatgaccatc ttgactggta ctaaactgca
     8701 agaaatcatt gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag gcgatatcat
     8761 cgcaagcaaa gctcttcttt caattggtcg tatgccagac cttgaaggta ttggagaggt
     8821 tgagtttgaa ttggatcgtg gttgtatcaa ggtcaatgaa tacatggaaa cttcagttcc
     8881 aggcatttat gcaccaggtg acatcaacgg tactaagatg ttggctcacg cagctttccg
     8941 catgggtgaa gtttccgctg aaaatgccct taaaggaaat catgcagttg ccaaattgaa
     9001 tttgactcct gcagccatct acactctccc tgaagtagca gcagtaggtt tgacagaaga
     9061 acaagcccgt gagaaatacg atgttgccat cggtaagttt aactttgctg ctaacggtcg
     9121 tgctattgca tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata agaaatacgg
     9181 agaaatcctt ggtgtacaca ttattggtcc tgcagccgca gaattaataa acgaagcatc
     9241 aagcatcatc gaaatggaaa tcactgttga ggaaatgctg aagaccatcc acgggcaccc
     9301 aacttactct gaagtgatgt acgaagcgtt tgcagatgtt ctaggaatgg ccatccattc
     9361 acctaagaaa aaataaaacg aagatagatt agactggaag gttatttcca gtttctatca
     9421 tataaagtaa agggatatca tgaaatacat tatcaatcat tcaaatgaca ctgcttttaa
     9481 tattgccttg gaagaatacg cctttaaaca ccttttggat gaggatcaaa tcttcctact
     9541 ttggattaac aagccatcta tcattgttgg tcgtcaccag aacactatcg aagaaatcaa
     9601 ccgtgattat gttcgcgaaa atggtattga ggtagttcgc cgtattagtg gtggtggagc
     9661 tgtttaccac gatttaaata acctcaacta cacgatcatc tccaaagaag atgaaaataa
     9721 ggcatttgac ttcaagagct tctcaactcc ggttatcaat accctgactc aacttggggt
     9781 taaagctgag ttcacaggtc gtaatgacct tgagattgat ggtaagaagt tctgtggcaa
     9841 tgcccaagcc tatatcaacg gccgtatcat gcaccacggt tgcttgctct ttgacgttga
     9901 tttgtcagtc ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat caaaaggtgt
     9961 gaaatccgtc cgtgcccgtg taactaatat tatcaatgaa ttaccaaaaa aaatcacagt
    10021 cgaaaaattc cgtgatttac tcttggaata catgaaaaaa gagtacccag agatgactga
    10081 atacgtcttt tcagaagaag aattggccga aatcaatcac atcaaggata ctaagtttgg
    10141 aacttgggac tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg gaaccaaatt
    10201 cactagtggt aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc aagacatcaa
    10261 gatttatggt gacttctttg gtattgaaga cgttgctgca gtagaagatg tccttcgtgg
    10321 ggtgaaatac gaacgcgaag atgttcttaa ggcgctaaaa accattgata tcacacgcta
    10381 cttcgctggt attagccgtg aagaaatcgc tgaagcggta gttggataaa tcaaaaagaa
    10441 gttggccaac taaccaactt ctttttttga tatttattta cataatttaa aatacgtaaa
    10501 atcataaact atctagagca ttcttttgtt catcattaac aatatgggta tagaggtcgg
    10561 tgacttgtgt gctggcatgt cctagttggt gactgactaa aacttgtgat ttagtcgcat
    10621 catagagcct agttgctagt gtatggcgca gtttatgggg tgttacacgc actttaaaat
    10681 cctctgagta tttagcaacc attttctcaa cgctagaagc atcgatacga ttaggaacac
    10741 ctctgtagag agttaaaaaa agggctgtat ctgttttttc cgttttatag cgttgattcc
    10801 gaatggccag ataattctct aaataaggtt tagcaaaagc agcgacattg actgagtcac
    10861 gtttgccacc ttttcgagta acatcaataa ccattatttt tagattgaga tctcttagat
    10921 ctagattaac agcttcagat aagcgaacac cagatgccaa gagaagggca ataatggcta
    10981 aatctcgttc tttatttttg ttgaatgatg agagagctcg atttgaaagc tgttgtgggt
    11041 gctcttgatc gatataagtt agaaaacctt ctgtttcatc acctagaaag agtttttgct
    11101 tgatattttc agctctggca gcaagggttt ctttcttttt cttggttgaa acttttttca
    11161 ttacattacg atagaaataa ggttccccct gatcgttttc aacctcctcg gttagatact
    11221 tgtaaagact agaaagtgct gataaggttc gattgatagt tgtctgtgaa acaccttgtt
    11281 ttgttgtatt agcattcagc aagggacgtt cacgtagata aaggataaag gattccatgt
    11341 ctttcttaga catattttcc aaaactgata aaggaatatc ggatatttta tcagcgtttg
    11401 aaataccaga ctccaaaacc cagctgaaaa atcggtcata ttccttaagg tattcgtaca
    11461 gggttgtaaa actgtagggc acagccagct tagattggta gtattccaga acataccagg
    11521 gcatgagttg ttttagtttg tcgattcgtt ccagtaaaat ctcacgtttc atgtattttc
    11581 tccataagta agtatactag tagtatagca tagacttgta tatttttcaa gaaaattata
    11641 gtttttcaga aagatgttat aggagttttt caaagtgata aaaagactta gacctacaaa
    11701 caaaacagaa taaggaaaat ctcacccact aaacttctgt taatactaca taactgaaga
    11761 gctatataag gagctatgag atacaaaaca cattgtataa tagattgaaa ctagaatagt
    11821 acatctggac ttctaaaaca ttgctagaaa ttgatttgat tgtcctgatt gttttatcct
    11881 atttctattt catttcacta tataattgct attgttttct ttttcatgat tttaatctta
    11941 ctgtacagat ttgatacagt aaactccttt ccagctttat gctttatcat ttctaactta
    12001 attatagtct tatttttaat aaagttcaat tatttatatg taaaattcct catcagtaaa
    12061 aaataaccga tctcatttct gagaatcggt tttctaaata aatcaaactg atcatttaca
    12121 taacataaat tatgtgaatg atcatactac aacaacaaat ctttgacttt tccaatttca
    12181 ctttttggaa taaccaggtg aatcatatca cccagataca ttctggttga gccgttaact
    12241 gtttggctct tgccattacg gacttgagtt gtgatgagga cgttgtgtgg taagttgagt
    12301 tcatgaactt gtttcccagc aattttatca gaaactggta tttcgataag tgtaacttct
    12361 ccttcgctag atacttcttc tggaagcatt ttttccagca tggcttcata gactggcgta
    12421 cctttgagca aatccatgat aatataagaa acaagagtga caagaccaag tggcatgagg
    12481 ttgcgaatat ctcctaccat ctcagttacg aggatcatag cggttaaggg agcttttgat
    12541 atggctccaa aatagccact cattcctaga atgacaaata tagggaattg ctcttgactg
    12601 acaagtccaa gattgacaca gataacacca actaaggcac caagcaaaga accaagagct
    12661 aaaatgggta ggaaaattcc tcctggcagt ccacttccat agctaatcat actccaaata
    12721 aagcggatca aaaagtaagc taataaaact tggaaactaa aattttgttc agttaaagaa
    12781 aggacaagct gatttccgcc accaaggatt tgaggtaaga agattccgac tggtatgata
    12841 aggataaaag ccaagatggg ataataagcc ctatccaaat ggattttttg accaatcaag
    12901 tcataaactc ttccaacgtt taatacagct ttctcataga gaaaacctga aaatccaagg
    12961 aaaattccca tgacgagata tatccaatac tggtctaggg tcatgggagg aatgttatct
    13021 gacatatcca atactggtgt caaaccgaac atgagtagag acacaaagtt tgctacgatg
    13081 ctggctgcta gagttgagac ccagaaaaag cgcgaaaaat ggtgatagac ttcttctaca
    13141 acaaagagaa gtgctgcaat aggagcatta aaggctgcgg ctaaacctgc tgcagctcca
    13201 ctggcaatca aggaacgttc ctctactgga ctggatttga gccacttggc aattccttta
    13261 ccaccaactg ctccaagttg aatgctgggt ccctctcgac ccagcatgag tccactggca
    13321 atagcaagaa tacctagcac atattttttc caaagaatgc cccaccagtt gagggacatg
    13381 aggcctttca gttcggcttc gacttgagga attcctgagc ctttaatatc tttttctgac
    13441 cgtgttagtt tggcactgag ccaacagatg agtatataaa acaaaaccag tacaaaaaga
    13501 ttgcgcacta agtacccttg atcttgataa actccttgta tcaggtggaa gcccttttca
    13561 attaagaaac gaaaggatcc gacgataatt ccaacgatga ggccgacaat gattcctcga
    13621 ccaacttggg atagtatagt gctggatgca aaggcgaatt ctttcttaga acggactatt
    13681 tccgactgtt cctccatggt atttcctttc aattaacttt cttttttacc taaaaccagt
    13741 gatttaacgg gttcaaagct ggttcggtga attggggtaa ctcctagttt tgtgaggcct
    13801 tccagatgtt tagctgtgcc atatcctgca ttagtagcga aatcatagcc agagaactgc
    13861 tgatcgtatt ctttcatcaa ttcatcacgt gttaccttgg ctactataga tgctgctgcg
    13921 atagagaggg agttggcatc tcctttgata atggaggttt gtgaaatggg caagtccagt
    13981 ttcatggcat caatcaaaag gtgctctggt tgagggctga gctgggagat tgcttcttgc
    14041 atggctagtt tggttgcttc atagatgttg acttggtcga tgacctgatt atctatgata
    14101 ccaattccaa tcgacaaggc ttggtcttga acggcttgga aaatctccag atgtttcttt
    14161 ttaggaattt tcttgctgtc gttgagacct ttaatcttac aatttttagg taaaataacg
    14221 gccgcagcga ctacaggacc agcaagagga ccacgaccaa cctcatcaat acctgcaatt
    14281 aaggtcaatc cttgcttata aagttctttt tcataagaaa gcatggattc caagcgcaaa
    14341 ttttcatcta attcagcttg aatggctctt ttacgcttgc tgatttcctt ttgaactcct
    14401 gagcgattat ccttttcaag atctaaaaaa atagggcttt ctaactcctt gactgtcaca
    14461 aggagttctt tgatttcttt aatcgttgcc atcgaggtct tccaatgtat ctaaggtata
    14521 gttaccgagt ttgccatcac ggacttcctt cacgaagaga ctgtaaaaac ggtcatagtc
    14581 atcacggaaa ccgagggcgc gggtcatatc cataataatc acaggcgctt cttcttcaat
    14641 tttcatttgt ttgaagcgtt cagccagctt ttctggataa tgttctttga aataattgat
    14701 accaaaaatg gtaacctcat ccataggaag caactgatcc ttgatagctc cagtcaatgc
    14761 caacttaagt gcaacagttt catcctcaaa cttaggccag agaatccccg gtgtatccaa
    14821 gatttccaga tctttattgg ttttaagcca ttgttgacct tttgtgaccc ctggcttgtt
    14881 tccaacaaca gcaatctttt taccagccaa acggttcatc agagtggatt taccagcgtt
    14941 tggaatcccg ataatcatgg tacgcaaggt ttcaatctga atcccacgtt ctttctggcg
    15001 agcaatctta tcagccatga gcttcttggc cgcatctgtt acaactttta cagtcacttg
    15061 ctctttggag ttgatagcta gcgtctggat tccttgtgat tcaaaatact gacgccattc
    15121 cttggtcatt gctggatcag ccaagtcggc cttgtttaaa atcaagagtt ttggtttatc
    15181 accaacaatc ttggtcaaca taggattttg actagataga ggcaagcgtg catctactaa
    15241 aatcgtcaca aaatcaacaa attttaaatt ctcctgcacc tgtcgacgag ctttagacat
    15301 gtgaccagga aaccattgaa tagtagccat tgagtttttt cctttcatag caaggattta
    15361 gatcccctat tttattttac tatagtttga acatagagag ttttcaaatg aatgatgtcc
    15421 aaacagttct tgttttatga catagaaatc tactttatat tatatcatgc cttctttatt
    15481 ttgtccgatg atagcctttt accctatctt ttaccctata ccctatccta tatagaaaaa
    15541 agccatcaaa tgatgacttt tcagagggag caaaaaactg ttccgaacca aaagaactaa
    15601 actaccaaca gctaataggc ctaaagctgt aagcgcagaa gttgatgaac ctgttgcagg
    15661 aagagtttcc tgctgataaa taagagcata acttacttca ttatcagtag gaattcctgc
    15721 ttgaatcttg gtttgttctt catcaccttt ttaaacttta tttcctaata gtaaacacta
    15781 ttttttattc tcaaaaattg aacttctaaa atcatttgtt tggtcaagat aggctttaaa
    15841 gattgctctc ttcaacttat gaacggcact gtcgatttct ggattataat tactccaacg
    15901 tggaccttca gcatccttga gaacagcttg gtccatgagg gcttgcaatt catccacatt
    15961 attgatagtc tttgtgccat agcttggcca tggttttgtc ggatctttaa aaataacttt
    16021 agtcaaatga tcaaactgag caatacgctc ttgatacata gcttttttaa aggctgtcca
    16081 agatggatac ttgccagaga atatcttttc caaaacaagc ttatctgtca ctaatccttg
    16141 ctttttaccg taaaggttga ttgtctgacc attttgttta gcaattcctt catattggtt
    16201 ggaaatatat ggtaccatac catctttaaa tcctttagca gctaagagtt cataagctat
    16261 ccttcgtccc ataagatctc caggagtacc tttctcactg ctcaatgctg aaaagattgg
    16321 tgcaaagagt tttatagtaa agtagccatt tctctcatat gtaccagcct tatactcacg
    16381 agctgaaaga atattattgt caatcaaact atcaaaacta ttcaggtttc gggcctcttc
    16441 ttctgtcaat tctttgacta cgttagtagc gtaaacctca tttccatcag caggatctgt
    16501 tagatattga ttctcgattt ttctgagagc ttccattttc tgagaaacat tcagtttctt
    16561 aacaatcgat tgcccttcta gatattccaa catatagatg aggtcaaaca tgttgtgaac
    16621 atagttttga agatctgctg agttttggaa tctttctgtc ggatccaaga cttgcagacg
    16681 cgatccttct aagctatctg attttgaatg tttcaagata gagttaatgg taatggtcgc
    16741 atcatatgga tggtctggcg cttgtaataa acctttagca aagaactcag gaccaagacc
    16801 acttcttcga ccatagccgc caaggtaaat atcttgatcc gaatcatggg tcatctcatg
    16861 ggtataggta atggctccat ccttgtcgag catgcggtaa gacatatagt agacaccatc
    16921 tcctgttgcg taggcaccgt gatgattatg aacaacctta ttaccaactg gaccaaagaa
    16981 attcttcatg gctggattgg agctatcaaa cttagcctcc actgtagctt ttccagatgt
    17041 tgtgtcatca ccaaacttat aggcatcata aaggagaatc gtacgatata gtttttcacg
    17101 tccctcatta tctaaaatgc gataccaata atcgtagtga tctcgctgac gtttggcagt
    17161 ttcactcgca ttttcttcaa cgaaattatt gaggtccttg cctgctttat gttcactatt
    17221 acggtagcga tcgtaagcac caaatcctag actagacaag gttgagatga caaatacaga
    17281 tctttctggc aaggtaagga gaggcaagac catattccgg tacttccaag tattactagt
    17341 aattcggtca taaacaccga tagagtactt agttcctgct tgcttttgct tggctttgac
    17401 ctctgcaata gtggattttt cttcgacaat gaaagctttg gtctgttttt taaaccagtc
    17461 attgttgcta gtgtttggta aaaagacttt tcggtaagtt tcaagtgcgc taaacaaatc
    17521 tgtcgttcca tgatggctgg ctagactgat accataagta tcgacattgt tcttggcaag
    17581 aagattgtta aagccagatt tacctaactc aatcagagta tctagtgggg aagtatttcc
    17641 tttaccaaag aagtctggat gatacataac taggtctttg acattcactt gaccatagtt
    17701 aaagttatac caacgttcta aataagttaa accgagtagc aaggcttcct tattattctt
    17761 gattttatct acaagatagc ctctggtgac tgagttatcg ctagctagac cggcatctgc
    17821 tgacaaaagt tttttcaagc tgcctcccag attttgtttt gttttggaga actgctcttc
    17881 taaatagagc tcggttaact taactgctgg agaaatacca agtgtctttc tgatagcatc
    17941 tgactggtaa tcaagcttct gcaactcagg caagacttcc ttaacaatag agtctcgatc
    18001 atataagaat tggttaggag tgtagagaag tcccgtatta cctagattat attctgctag
    18061 attggcaaaa tcagtctggt acttgagatc aaatttctca gatgaatggt cattatagtg
    18121 aagtaagagt ttgtttgcag tctgtttgtt ggaaacaata tctgtgatta cttggtcatc
    18181 cttcatcata actgcagata agagttcttt ttggtataag agactgttct ccttaaccag
    18241 gtttccgtat ttcacgatgg ttgacttatt ataaaaaggt aacaattttt caatgttctt
    18301 ataaaccaaa gcacggttag cttgataatg ggctatctta gaaaaatcac tgtctttctt
    18361 gccacttgtt gagaggggtt ccaccgttgg tagagtgaga ggacttattt ctgctttttt
    18421 gcttacaatt tgagaagcat ctagcattgt tcctctttct tcaaaggatt ccttgctgac
    18481 gacctcatcc ttctctaaag tgacattgaa aactctatta gccttactac taaatgtatt
    18541 agctaccttc attcctgtat agtggtatcc agtgatggca tttccgtttg ttacattaac
    18601 atcgctgaga acatttgtca aacttccagc atgcctaaca tcaccagaag ttcgatccca
    18661 caaattgcct gccactccag cgactctacc aaagtgcttg acattgttga tatcaccttc
    18721 agcatagcta tcttggatct gtgcatctcg gtctactaga cctgcaagac caccgacagt
    18781 ctgatctgac ctattggtgt ttgacgaaat ggttactgtc gctttggatt tagcaataga
    18841 cgcatttttt cctgttaaat gaccgaccag accgccaata ttgtaggaat cagtcgtttc
    18901 ataggtattg acaattcttc ccttgaaact gctctctgcg atgcttgatt ggtctgcctt
    18961 agccaacaaa ccaccgacac cacgttctcc agccagaaca ccatcaacat gaacttgttt
    19021 aatctttgtg ccattcgtag cttcatttgc cagtgaacca atatcatttt tccctgaaat
    19081 agcaacattt tttagactca gtttttctac tgtagcacca ctcaagtttt caaacagagg
    19141 ttttttcaaa ttatagatag cataattctt gccatctttt tcaccgatta aacgaccagt
    19201 aaaggtgtcc ttgatatagg atctttcatc aggaccaagc tccacttcgt tagcattcag
    19261 gctggccgct aaatgatagg ttccagaggg attttggttt atagctttga ccaggttgct
    19321 aaaggaagta aagtttgtat tttcctcttt agccttctta tcgaggtaga aggtgaaatt
    19381 gtcgacatat ttattttcta gttcttgctg gagtttctca gctttggctg tgattttata
    19441 aactgactgc ccatttcttt tctcttcggt tattgaagct actggtatat agacatcttt
    19501 aaatgctgaa gattttacct tgacaaagta agtatccgta ttctctggaa ttccatccaa
    19561 tgaaacatgt tgtctgtagg ttccattcgt ctgactatac aactcaatat cagaaacatt
    19621 tcttaattcg agttttttct ctggttctgt ttgtccattc tctgatgttg tattacctga
    19681 attttctggt tttgttgcag ttccgttttt ttctggttga tttgattctt caactggtgg
    19741 ttttgaatca ctaggtttat tggatacttc tccagtattt tcgttagcta ttttcccaga
    19801 gtttgtttgt gtttcttctg caggttgaac tggtttttct gtttcttgat ttgaggtacc
    19861 ttctactgtg ccttcatttg gatttactgg aacttcttct acagtttttt ctgaattttc
    19921 atttttagag tcattatgtt ctggtttatt tgattctcca actgaggttg tcgaatcact
    19981 aggattactg gacacttccc cagtattttc gctagatgta tctggtgata ctttctctga
    20041 attcgttgtt gattcttctg caggttgaac tggattttct gcttcttgaa ttgaggttcc
    20101 ttctgtagta ccttcatttg gatttactgg tgtttcttct gttggtttta ctggaacttc
    20161 ttcagttttt tctggacctt gttctttggt cttctcaacc ggagtttcag gttttacttg
    20221 ctcaatatta cccttatatt ctgtcaatgg ggctacctgc tctggttcac ctttatcact
    20281 taccacagta tctggcgact ctggttgaac ctcagtctca cctttgtcgg tcacaactgc
    20341 ttcgggtaat gtcggttgaa cttctggttc gcctttatca cttactacag cttcgggcaa
    20401 ctcaggctga attgcgggtt caacaatagc tccagactgt acgtccttat gttctacacc
    20461 agtctcaggt tgttccttta taacttgagt ttttttagta cctttttcga ctattcttgg
    20521 actaggcgca gtcgttgaag ttgaaacaat ttctcgcgaa acttcttcct tgtttacaga
    20581 gaatattctg acgatttcaa ctttcttacc taatttacct tcttgtttta ctcttacagt
    20641 tccttcagct aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtctctat
    20701 agtttcctca cgatataaga gttcaggttt gttcaattga cctgataaaa cttcatcctg
    20761 tggatttaat gtatttaccc cagtcttttc ttttggagaa atcttctcct ctttcttcgt
    20821 ttctagattc ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt
    20881 tcttggattg attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt
    20941 agttgaagaa acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa
    21001 atttggtgta acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc
    21061 ttgattactt acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt
    21121 gtaacctgaa atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt
    21181 attgtaattt agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc
    21241 cattcccgca accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac
    21301 agcaaaaatt aaaattccca gagcagctaa gctagcacca gcaactaggg cttgcctctc
    21361 attcttgctt ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac
    21421 aagataataa gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt
    21481 cttttcttct gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc
    21541 ttgagcatcc acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc
    21601 agatacaagt cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata
    21661 cttttccatt attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat
    21721 tagtgtatta tctattatct atagaaaagg cagtatacct taattatact cttaatttac
    21781 aaaaaagtct taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca
    21841 ataacaccta ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa
    21901 atggtttgag gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat
    21961 ggtcttcctg caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt
    22021 caaaggcttt cattttatag aaaaagtcga tgagatgatc tgacaggtat tcagttgaaa
    22081 agggtacttc accacttttt cgatattcta ataagagtct agaaaatcga gctttttctt
    22141 caggaagctc acgaaaatag gaattgagga tccaagtctg cttctgtttt ctttcaattg
    22201 gatcctgact ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga
    22261 tagctcgttc tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag
    22321 tcagggtctc tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta
    22381 gaaccagatt gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg
    22441 cctggatacg gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga
    22501 gttggtcatc cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca
    22561 tccgagcctt tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga
    22621 aaagctggta gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt
    22681 tttcccagag ccattttaga agtcgctcgt caaagttact tttattgacc ttgatttttt
    22741 cctttttctg agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt
    22801 ccaattgctg gtcaagggac aatcgatgaa aatgacgaac acagtcgcta ccaattggaa
    22861 agaggcgttg gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttccac
    22921 agacacaatt gctacggccg ataccgttaa aaataaagga aacttcattc cattccttgg
    22981 tagcttgttc ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc
    23041 taactggaag tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta
    23101 gaaagctagc cgcagtcagc tcaaaacact gttttgaggt tgtagataga actgacgaag
    23161 tcagctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagt aaccatatat
    23221 acagcaaggc gaagctgacg tggtttgaag agattttcaa agagtataag ttatactttt
    23281 acaacttgaa cctcgtcttt accgagtaaa atcaagtatt tttcaatatt ttcaatcgaa
    23341 taggctcgtg ataaagcctc ttcgtataga gctaactgac cacgatagcg gtctacgagt
    23401 tgacttggtt catcatagcg gtctgtcttg tagtcgaaca gaacaatttt gttttcgtaa
    23461 agcagatagc catcaaggat accacggaca acaaagtctt cctgactctt ttggtctcgt
    23521 ttgagcatgg agaaaggttg ctcgcgataa agatggtcgg tattagcaag aatttcctga
    23581 ccgagtactg tgtcaaagaa agcaagaatt ttatcaagat tgatcttgtc tctgacagct
    23641 tggctagttt gaacttgttt gagtgtttct gttaggctag caagggttag ttgctggctg
    23701 aggtcaattc tctgcatgag ttcgtgagta gcactaccaa tctcagctcc agttaccttt
    23761 tctttggtta aaaaatctgg caaatcgaag ctgattttct tgcctactga ctgaccttga
    23821 ccagcaatct cgacaccttc catatccata actggttcgt agaatttctt gatttgactt
    23881 ggggtttgaa cactaggaag ttcaatagct gcgcggtgaa gagtattata aacttccacc
    23941 tccttcagca tttccagagc ttctttgatg gtatctgact gacgattgtc tgcttgggag
    24001 ctatcttgga gaggactctt ggtttccaac tctccgatag cttctctggt caactgatct
    24061 tcgccaataa aacgataact aaagttgagc ttgtccttag taaacacttt actgataacc
    24121 caaagccaat cttggaaatt ccgtgcttgc agtctagtat tgctatttag tttcccattt
    24181 ttggctgctg ggtattcctt ggattccagc ttttcacgag aacccttgcc gacaagatag
    24241 agctttttct cagcccgcgt catagcaaca tacagcaaac gcatctgctc agaatagctt
    24301 gctagctgta attcctcttc gttctgccta taggtcagac taggaatgga gagtttgatg
    24361 gttttaggat agtggtcttc tactgcccct gtctccatct tggcaatata tttgacacca
    24421 agaccattct gacgactgag aatgacttct gacatagagt cttgcttgtt gaaatcttga
    24481 tccatattga ggataaagac gtaaggaaac tccagccctt tactcttgtg gatggtcatg
    24541 agctctactg catcttttgg cggtgcgacg gccacgcttg ccaaatcgtg ctgggcttct
    24601 aagacttggt caatcatacg aataaaacgc gacaaacctt tgaaattgct cttttcaaat
    24661 tgatcagcac gcagtgctag ggcatagaga ttggcctgcc tagcaggacc attcggcaaa
    24721 gccccaacat agtcataata aaaacggtcg ttgtaaatct tccaaatcaa gtcatagaga
    24781 gagtgggttt tggcatacaa gcgccaagaa gctaggatat tcatgaattg ctttagtttt
    24841 tcagctagag ctgtgtgaat caagcctttt tgactacttg ccattttttg tgcattgacc
    24901 agtttctcat agagattttc gtggacttta tcctctgctt tctgaaggga caaacgtgct
    24961 agctcatcct catcaaaacc aaacattgga gacttcataa gggcaaccaa ggcgtagtct
    25021 tgcaggggat tgtgaatgac acgaagagtg tctagcatga cttgcacttc tagggattgg
    25081 agataattgt tttgctctcc gtcagttttg acaggaatcc cgtactcaga cagggcgagg
    25141 agaatctggt cattacgact gcggctggag gtcagaaggg caatttcctt aaaggcaaca
    25201 cctttttctt gatgaagttt cagaatctcc ttgataacta agcgcatttc gcctgttagt
    25261 ttcgtttctg tttgactctc ttcttcctca cctgtatcgt ccttgtcgta gaggagaaat
    25321 tctgccttgt tgtctggatt gggagtcagt ttggtattgg caaaaacaag ctggtgcttg
    25381 ttatcatagt tgatttcgcc gacctcttgg tccatgagac gttcaaagac atcattggtt
    25441 gctgacagca cttctgaact actacggaaa ttttccttga ggagaatgag cttgccttct
    25501 tggggatttt gcgcatagcg ttggaatttc tcattgaaaa tctgcgggtc tgcctgacgg
    25561 aaacgataga tggattgctt gatatctccc accataaagc gattgtggcc attagacaac
    25621 aattccagca tccgttcttg aatatggttg gtatcctgat actcatcgac catgacttca
    25681 tggaagcgct cctgataaga ctcacgaact tgtgggaaat tctctaaaat ctcaatggtg
    25741 taatggctga tatcagtgaa ttcaaaggca ttttcctggc gtttgcactg acgataagcc
    25801 tccacaaaat gactcataaa ggtttggaag gttttagcta gttcccatgt gtcttgatga
    25861 taacgttctt gatagtcgag aatggttatc tggtctgata attgtcctag tttagcaaac
    25921 tgggtctttc tctcttcgtt gtaggcatca gccaggggct tcaaatcagc cttacgactg
    25981 gcattagtca gagctcgacc gtttttctcc ttagagatgg cgacaacacg cgcaagcact
    26041 gcctgataag cctgactatc ggactcctga tttagggagt caatttcatc cagaattaac
    26101 tgaacatttt ctaaataggc agcctttgca aactccttgg catcgttatc cagatggtaa
    26161 cggaaaaagc tttccaaatc ccaaagggct tgtttgatct gctcagtcag tttttctttt
    26221 tcactggtaa aatcagcttt ctcaaatcct ttgaggaaag attcactcag ccacttttga
    26281 ggattactgg tggattggag gaagtcatag attttataga cctgctggcg cagaccccgt
    26341 tcgtccttgc cacgcccagc aaagtttttc agcaaatgac taaaggtctc tttctgttta
    26401 ccttggtaat gcgcttcaaa gacctcatga aagacttcgt tttcgagcag aagttgctcg
    26461 ctttggtttt gtaaaatacg gaaattaggt gcaatatcaa gcagataacc atgtttgcca
    26521 aggaattttt gtgtgaaaga gtccatggtt ccgatggcag cgttgggtag gtctgccaac
    26581 tggcgaccca agtgttgttt gaggtcgaca tcatctgttt cttggatttt cttgctgatt
    26641 tttttctcta aacgttcttt aagttcagtt gcagccttga cggtaaaggt tgagataaag
    26701 agttgagaaa tttcgatacc acgcgccaat tggtccagaa tgcgctctgc catgacaaag
    26761 gtctttccag aaccagccga tgctgagacc aggatattct gaccagaagt gtagatagct
    26821 tcgatttgct cggcagtttt cttctgttct ttgctcgaat ttgcttctgc ttcttgcagt
    26881 ttttgaatct cctcctcact taaaaaggga ataagcttca tcgattcaac tcctctctta
    26941 ttttttcaag ccaagcttgc ttgagttttt ctccgaccag acgcttgcca tcagctaggt
    27001 ccaacttttc taggaaacgg gcttggccca gatggtaatt ggcttcaaag cctgtaatag
    27061 cctgatgttg ctggacgtat ggggcaatgc ttctgccatt ttcagtataa ggattgatgg
    27121 cgaaccggcc tgctaaaatc ttctcagcag ctttcttgta aagataggca ttgtagtcca
    27181 gtaggagctg aaattcctca tctgtcagtt gattagcctt gtttttgtta taaaattcgc
    27241 ctaaataact gctttctttt tccaagaaga gcccttggta tttcatagat ttgctggctt
    27301 ctaccactgc tcctgccaga ctttttaccg ccatcagaga ttggacaggt tcagccattt
    27361 ccaagtacat ggcgccgaaa aagttctgct ccccttctct ttttagggca gcaagatagg
    27421 ttggtaactg agaattgagc ccattaaaga aatgaggaaa ctggaactga gtcagactgg
    27481 atttgtagtc tactactcct atcgctccat tagctttcaa acggtcaatc cggtccacct
    27541 tgcctcgtac aaagacactg cgtccattgt ctaattgaat aaaggcttgg tcttttccac
    27601 caaaatttgc ttcttctttg atggtttcga tggctggatt gtgtcggaga atatgtccag
    27661 ttgtccgtgc aacatcaagc aaaacttcct tggtaaactg ggcttccaaa ctttcttgat
    27721 aaatagcttc aaattcgcgt tcttgactgg tttcttgaat agcttgttct agacgttggt
    27781 caaaggaatc ttcattaggc aactgcaagg cgcgttcaaa gatacgatgc aagaaattcc
    27841 cgtgactacg ggcatcagga cgcaaacgta attcctcctg caagcctaaa acgtagcgta
    27901 ggaaataact gtattcattg cgataaaact ctgtcaaacc cgacgtagac aggtaaaact
    27961 cctgtttgtc aggatagaga gcttgcaagg tgtccttggc taaggtcttg ctgcttggac
    28021 tggttgggat ggctggattt tccagacctt gctgctctag ttttttacct ataacacgcg
    28081 acaaaacctt gacaaaagtc aaatcttgct cagtatcgct catctcaccc tgctggtgat
    28141 aggcaaccag actagacaaa agactgtgat aggaccccat atcctcctta gacagtcctt
    28201 tgtgattcat cctcttctct ctccgcctaa atccaaaatg gatcaactct tgaagatagg
    28261 cagattcctt actttcactt tcgttaaaaa ggcttggagc cgacaagaac aactgcttac
    28321 gagcagaatt gaccaaggaa agcatagtgt agcgattttt cttgagattt tcactgctgg
    28381 caatcagtaa ttgaacgcct tcttcggtcg cttggtttag attttgcctt tcttcatctg
    28441 tcagaagact ggtgttttga gaaatttttg gtaaattgtc ctgagttagt ccaatagcat
    28501 agacaaagtc agcagtcaat ggtgcaatca aatcgtaact ctgcaccaga acagtgtcca
    28561 ctgttgctgg aatggtacgg tattgggaca aactcattcc agaatggagc aaggctagga
    28621 agtcttccag actaacctgt gaaccagcaa aaacagtcgc aaattgttct aaaacatggc
    28681 agaaagcctt ccaaacttcg gcttgtcttt cctgttctac agcttccaaa gtggttgtca
    28741 aatcttgtaa ctgcttggtc acagctcctt cttttagaaa gacactccat ttttgtagga
    28801 gtttttcagc cttttgtttt cggctggcaa agaggatttc aagaggtgct aaaattctca
    28861 ggcggaggac attcaaacgc tcaagattaa attttccatg gtgggatttg gtgaaggttt
    28921 gctgaaaggc tggcaagcca ttgataccaa gatagcggat atattgctca aaagcatcaa
    28981 tatcagactg actgaggtca gtatacaaat cagttctaag aagattaatc aaatcctcct
    29041 gacgaaaacg gtaacgtttt aaagctaaaa tagactcgac aaactgagtc aagggatgat
    29101 gagccatggc ttcgcttcta ccaagataaa aaggaatctg atactggtca aaaatggttt
    29161 tgagagataa ctggtaagaa gctacatccc ccaagagaat acgaaaatgc ttgtagctca
    29221 ggtctgagtt ctcatgtaat ttctgacgaa tactacgggc tactagctcc aactcctcct
    29281 tttgcgtcaa acaagaccag atttgtaaat tttcacggtc tttctcatcg acatccaaag
    29341 cgagttctga aaagtcataa gaagactcca acaaacgaga ggccttgtca aaactatcca
    29401 tcttctcatg agtttgagaa cagtcctgag caggcgtttg gtatttagaa gccagatgat
    29461 ggagaaattt tacgctggct tggtagagat tgccctcgct aaaaggactg gtataggctt
    29521 tcttactagc ataagccccg ataacaatct caacaccttt gccgtgaagt aagtccacaa
    29581 cccgctcttc ctcagcagaa aaacgagtaa agccgtcaat gaccaaggcg atttgattaa
    29641 aatcactact taccttgtca ttctcaatag cctcaatcaa atgggacaac tgacttccct
    29701 gggctaactg accttgatta agataggctg ttactttctc aaaaatcaag agtaaatccg
    29761 ccctcttatc ctcatctgtt aaattctcca agtccaaaaa actcatctga gatttggtca
    29821 tctcatggta aagctcaatt aactgctgga tcaattgagg atcctgctta atagcgccat
    29881 aaacacgcaa gtccttggga tcgagttcgg caaggcattt gtaaaaggcc aacccaagac
    29941 cgatatcatc aagagtagtt ttagctggta aatcattcaa gaccagatag cgagccattt
    30001 gagcaaagcg cgtgacggta atcgaaaaag aagcctgctg ggacaagtat tccagcacgg
    30061 cgcgttcctt ttcaaaagaa agagagttgg gggcaatgta gaagacccgc ttgccagctg
    30121 caactagctc ttctgcctct cttgttagaa tttctgtcaa agaagtccga atatcagtat
    30181 aaagtaattt catctcagcc tcgttggaat ttttcatcac cctatattat accatgatta
    30241 gcctcgtaaa tctgttaaaa tatttaggcc atcctttctt ttcttcatca tctgctaaat
    30301 cttaaatact tagctttact tgtattagat agaataagtc tggctactga aaatcacata
    30361 ataaaaaagc ctcggtaaca aggctttgag ttttatgatt gtttcttagg tacggaatac
    30421 acttcaatgt gttgtcccag tatcttaatg tcgacgggta gattgtctga tttatcgcaa
    30481 tcaacatcgg actctaattc gatatcagaa gaagttttaa tattacgtgc ctttatatat
    30541 tcaatattct tgatagaatg attgaactat agtaaattga aactataaca gtacaccgtg
    30601 gatgctaaaa tatttctaga aattaatttg atttccctaa tcaagctgtt cgtatcttat
    30661 ttcaatc
//
LOCUS       DAVLGK010000025        30637 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLGK010000025 DAVLGK010000000
VERSION     DAVLGK010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30637
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.025"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(196..1056)
                     /locus_tag="VXE01_001228"
     CDS             complement(196..1056)
                     /locus_tag="VXE01_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV0750131.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDITKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1072..2349)
                     /locus_tag="VXE01_001229"
     CDS             complement(1072..2349)
                     /locus_tag="VXE01_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0750132.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2342..2893)
                     /locus_tag="VXE01_001230"
     CDS             complement(2342..2893)
                     /locus_tag="VXE01_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0750133.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(2909..4168)
                     /locus_tag="VXE01_001231"
     CDS             complement(2909..4168)
                     /locus_tag="VXE01_001231"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0750134.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(5361..5519)
                     /locus_tag="VXE01_001232"
     CDS             complement(5361..5519)
                     /locus_tag="VXE01_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750135.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(5529..6839)
                     /gene="obgE"
                     /locus_tag="VXE01_001233"
     CDS             complement(5529..6839)
                     /gene="obgE"
                     /locus_tag="VXE01_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0750136.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENIEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(6903..7037)
                     /locus_tag="VXE01_001234"
     CDS             complement(6903..7037)
                     /locus_tag="VXE01_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0750137.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(7096..7272)
                     /locus_tag="VXE01_001235"
     CDS             complement(7096..7272)
                     /locus_tag="VXE01_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0750138.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(7303..8628)
                     /locus_tag="VXE01_001236"
     CDS             complement(7303..8628)
                     /locus_tag="VXE01_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0750139.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(8644..9687)
                     /gene="cpoA"
                     /locus_tag="VXE01_001237"
     CDS             complement(8644..9687)
                     /gene="cpoA"
                     /locus_tag="VXE01_001237"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0750140.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(9802..10131)
                     /locus_tag="VXE01_001238"
     CDS             complement(9802..10131)
                     /locus_tag="VXE01_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0750141.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10145..11254)
                     /gene="rpoD"
                     /locus_tag="VXE01_001239"
     CDS             complement(10145..11254)
                     /gene="rpoD"
                     /locus_tag="VXE01_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0750142.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(11257..13017)
                     /gene="dnaG"
                     /locus_tag="VXE01_001240"
     CDS             complement(11257..13017)
                     /gene="dnaG"
                     /locus_tag="VXE01_001240"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0750143.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLTQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(13107..13865)
                     /locus_tag="VXE01_001241"
     CDS             complement(13107..13865)
                     /locus_tag="VXE01_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750144.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMGLTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(13862..14728)
                     /locus_tag="VXE01_001242"
     CDS             complement(13862..14728)
                     /locus_tag="VXE01_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0750145.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPIF
                     KQTILKGAKLSK"
     gene            complement(14797..15801)
                     /locus_tag="VXE01_001243"
     CDS             complement(14797..15801)
                     /locus_tag="VXE01_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0750146.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(15914..16131)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16214..18910)
                     /gene="ppc"
                     /locus_tag="VXE01_001244"
     CDS             complement(16214..18910)
                     /gene="ppc"
                     /locus_tag="VXE01_001244"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0750147.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDKEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(18930..20159)
                     /locus_tag="VXE01_001245"
     CDS             complement(18930..20159)
                     /locus_tag="VXE01_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0750148.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(20315..20617)
                     /locus_tag="VXE01_001246"
                     /pseudo
     CDS             complement(20315..20617)
                     /locus_tag="VXE01_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(20722..21011)
                     /locus_tag="VXE01_001247"
                     /pseudo
     CDS             complement(20722..21011)
                     /locus_tag="VXE01_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821711.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            complement(21260..21847)
                     /locus_tag="VXE01_001248"
     CDS             complement(21260..21847)
                     /locus_tag="VXE01_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEV0750149.1"
                     /translation="MGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            complement(21926..22353)
                     /locus_tag="VXE01_001249"
                     /pseudo
     CDS             complement(21926..22353)
                     /locus_tag="VXE01_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(22409..22711)
                     /locus_tag="VXE01_001250"
     CDS             complement(22409..22711)
                     /locus_tag="VXE01_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750150.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            complement(22986..24725)
                     /locus_tag="VXE01_001251"
     CDS             complement(22986..24725)
                     /locus_tag="VXE01_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV0750151.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKIPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            complement(24888..25772)
                     /locus_tag="VXE01_001252"
     CDS             complement(24888..25772)
                     /locus_tag="VXE01_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0750152.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(25884..26738)
                     /locus_tag="VXE01_001253"
     CDS             complement(25884..26738)
                     /locus_tag="VXE01_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0750153.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(26796..27554)
                     /locus_tag="VXE01_001254"
     CDS             complement(26796..27554)
                     /locus_tag="VXE01_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0750154.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            complement(27616..27804)
                     /locus_tag="VXE01_001255"
     CDS             complement(27616..27804)
                     /locus_tag="VXE01_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0750155.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(28125..28691)
                     /locus_tag="VXE01_001256"
     CDS             complement(28125..28691)
                     /locus_tag="VXE01_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750156.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(28959..>30637)
                     /locus_tag="VXE01_001257"
     CDS             complement(28959..>30637)
                     /locus_tag="VXE01_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0750157.1"
                     /translation="SKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIVG
                     EYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIMQ
                     DYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEDRIQKAREGKWNGG
                     FAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNGK
                     NPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAIV
                     SDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKDG
                     TKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEKI
                     NMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYRM
                     YDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISALI
                     SEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
BASE COUNT         9113 a         6761 c         4940 g         9823 t
ORIGIN      
        1 taatagtata taggaggaga gccctgaatc ctagaccctt tgttatgatg cgcttacaaa
       61 cagagttgga aaaaatctta aaagcagaaa aacgcatgat atcagctcct aacacttgat
      121 acaatgcgtt ttattatgaa aagatctact ggatttttta tcaaaataaa cttccagtag
      181 tcttttcact ttttattaat aagttccttc ttcaccttgg ctagtcaaga taacaggtcc
      241 atctttcgta atgacaaatt ggtgttcata ctgacatgac aatccaccgt caatggtctt
      301 atgcgcccaa ccagttttca tatctgtatc aatttcccaa tcgcctgtat tgatcattgg
      361 ttcaatggtt aagaccattc cttcacgaag acggagtcca cgacctgcaa taccatagtt
      421 aggaaccatt ggttcttcgt gcatagttgg gccaacacca tgaccaacca aatcacgcac
      481 tacaccgtaa ccacgacttt cagcgtattc ttgaatagcc gcaccgatat caccgatacg
      541 atttccaaca acagcttgct caataccctt gtacatagct tctttggtta tatccatcaa
      601 gtttttgact tcttcggacg gtgtaccaac agcataagcc caacatgagt ctgctaaacc
      661 accagaatag ctctgagtgt attttttcat ttgttcaaca ttgttgaagt ttaattttga
      721 gacattcagg tcggatttag caatgggacc tcccaaaacc atatcaactt tgagcaaatc
      781 accatctttc aagatataat gacgagggaa agcgtgagcc acttcatcgt taagagagca
      841 acaggtagca taaggatagt ccatcatggc accgtcaacc ccaatctgaa gtggaaggaa
      901 attttcttct ttacaacgac ggcggacata ttcttcaact tcccacatat ctacgcctgg
      961 tttaatcaaa tcacgtaagc ctatatgaat acttgctaga aaatcaccag ccttgtccat
     1021 agcttcgatt tcacgagctg attttaatgt tatcatcttt tctcctagtt tctaattaat
     1081 tttaacagtc acatttgctt ttgaaacaat ctggtgacca tgataaatat cgtaatcaat
     1141 tatagctgac cgtctcgtat gatgaataat ccgtgcctga atgcgcaata tatcatctat
     1201 ctgaacagcc tgcaaaaagt agatcagcat ctgctcgata atgagattgc gaccactatt
     1261 aacaactaaa tcttgggtca tgtgggtcag aatttctgcc aatacaccat tagccaaaac
     1321 tccatttttt tctagcataa agggttccac tgtaataact acttcatcat ggtgataaga
     1381 gagcttttgt ccaatctgct cagaaaaagt tggtagagcc gaaacttggg aacggctcat
     1441 cttctccatg acatctcgtc gcgtcacaac gccaagcaaa gtttgattgc ttcgaacaac
     1501 tggtaccatt tcaaagtctt ctgcgatcat ccgttgactc acattggcaa tatttgtcga
     1561 taatccaacc aaaaatagac tacgagacat aaccttatca attgtcgtgc ttggtgattt
     1621 atcaccagcg tctctcatgg ttacaacgcc aacaacgacc tgatgttgat tgataacagg
     1681 gaaacggctg ctacgattct tacgaaccaa gtccaaataa tctttaactg tatctgtctc
     1741 tctcagaaaa ccatactcat gactagggcg ataaagtttc tcaactgtca gaatatcagt
     1801 cttgatttgg acatttgaca aggctttatt gatcatggtc gcgacggtaa aggtatcatg
     1861 cttacttctt agaacaggaa tccctttttg attggccagt ttaagcacat catcatgaac
     1921 ctgaaatccc cctgtaacca gaactgcatt ttcattttcc aaggctagca actgaatacg
     1981 ggttcggtct ccgacaatca agagcccccc atcatgaagg taagacaaga tattttgttc
     2041 agtcatggca ccaattgaaa acttactaaa ttctctctct aaaccttctt gcccagccag
     2101 aacctcagaa gaagtcactt ctgcaatttc agcaaacgtt aatctctcta tagcaacttt
     2161 ctgggattta acacgaattg ttccacttct aggacgggtc tccacaattc cacggttttc
     2221 agcttcttta atagcccgat aggctgttcc atcactaact cctagatgat tcgaaatgct
     2281 acgaacactg acccttttac ctactggtaa ttcctccaaa tagcttagaa tttcctgatg
     2341 cttactcatt gaactctcct tttacatacc gaaattcaag ataatcccgc atttttcttg
     2401 tgtaacgatc acttccctta aactgacgga acaaactaaa tccagactta agagcaactc
     2461 tttggctagc tttattttca aggtgggtaa tgatagataa ttgttttaag ccaaattcct
     2521 caaaagaaag ctgacaaatt tttctaacaa cctctgtcat aaatccttgc gaccaagcat
     2581 cttttctcaa aaaatagcca agctcagctt cttttttgat ttcatctaac ttctcaaatt
     2641 taatagaacc aatcatttgt tgatttttct ggtcacaaat tgcccacact cccaaagggg
     2701 acttcataaa gtaattggcc agtgcatatt gactttcttc cagacttgcc tgcgttggga
     2761 aaataaattg aagattttct ggatttgaag ctatctcgcg gaagtcctga ctatcactaa
     2821 aaaagaaagg acgcaaatac aagcgatccg tttcaaaaaa agaaaacatt gctaatttgg
     2881 tccaaatatt cataaacacc tctacggttt aatcctcaac aagtctaata tccgctccta
     2941 aattacgtaa tttttcgata atatcagaat aaccacgtaa gataaactcg atattggtaa
     3001 tttcagtttt accttcagcc ataagcccag caatgactag tgcagcccca gctcttaagt
     3061 cggtcgcttt aacactggcc ccacgtaaat cacgtccacc cgtgtacaaa atatgaccat
     3121 ttgttgtcga aatatccgca tccatctttg ctagttcaaa aacatgattt acacgttttt
     3181 cgtaaatcgt atcgacaatt gtaccacgac cattcgctct tagtaaaaga ggggtaagcg
     3241 gttgttgcaa atcagttgca aagcctgggt aaggagctgt cttaatattg attgctttca
     3301 aattagactg ttcctcgaca aaaatgctgt cttcagatac agtcattctc actcccattt
     3361 cttccaactt agcaataaac ccttccaggt gttcgtaaag aacattattt atacgaattc
     3421 ctttaccaac tgcagcagct aaagatatat atgttccagc ttcaatgcgg tctggaatca
     3481 cctgatgacg tgtcccatgt aatctttcaa caccatcaat aatgatgata ttagttcctg
     3541 ccccacggat atgggcaccc atattattca agagagtagc tacatcaata atctcaggtt
     3601 cacgggctgc attttcaata atagtacgac catttgcttt aaccgcagca atcatcgtat
     3661 taatcgttgc tcccacacta accgtatcca tgtaaatact tgcaccatga agtcctgtat
     3721 ctttagcaga taacttcatg ttatctccct cgtagctagc agtggcaccc atagcttcaa
     3781 acgccttaag gtgtaagtca atcggacgag gaccaagatc acatcctccc ggtagaccaa
     3841 ctgtcgcttc accaaaacgg cctaagaggc tcccataaaa atagtaagat gcacgaagac
     3901 tgttaatttt accataaggc attggaatat tttgaacacc tcttggatca atctccaaga
     3961 catcgtcata acgcttaaca gtagctccca tcaattccat gatttcgaca agactggcta
     4021 catccgaaat atctggaaca caatccaaag tcaccacatc atcagccaat ataatagctg
     4081 gaattaaggc cacaacacta tttttagcac cactaatagt aatttcacct tgcagtggta
     4141 atccaccatt gataacaatt tttctcattc taagttttca atactctttc aagatttcta
     4201 ataaggtctt caaaataaag tatatcataa atttatcctt ttttccatcc ttttcaattt
     4261 tattggataa atcagagttg acgagttagt aactgaatta ctaatactca ataaaaatca
     4321 aagatcaaac taggaaacta gccgcaggtt gctcaaaaca ctgttttgag gttgtagatg
     4381 gaactgacgt agtcagtatc ctacacgtac ggcaaggcga tattgacgtg atttgaagag
     4441 attttcgaag agtataatct ttctcgaatc gctattgccc cttttttatc ctctgaaacc
     4501 gagtaggagc taagactaga tctcttatct aagtatcgga atacggctgt tcaactaaat
     4561 tttatcaaga acttctcccc cttctctcag ttcacagaag cgttttatac ataccgtccc
     4621 tatatttcat gaacaagacg ttttcaggct agcatcctat cagacaatct attttaaaga
     4681 taaccgtgac tcaggatcgc ttctatctgt cgttttctct ttatagtgat agacctcacg
     4741 ggataagtcg tacatctttc ctcgtgtata gaagatatga ggacgttaaa aggttacagt
     4801 gaaaatagaa aatcttagta cgaattcaat tactctcgtg atttacgcat ataggttacg
     4861 actacctttt tggactttag tgcttttggc ccccttatcc gctatataca ccttattatc
     4921 acgttcttgt tcgtagagcc acgatttcgc tattccttct tctgacaatt cttatttcca
     4981 gcgtcagact taaaacggtc tatccccaga ccattttaat ccgctacctc acgatagtca
     5041 ggcttgggaa tcgctatttg actcgccgag aactttgaca tcagatatac tataacaaat
     5101 tgaaataaga ataaaacaat ttaattttga aattcaaatc aatttataac aatatagttg
     5161 attgaaacta gaatagtaca tctctgcttc taaaacattg ttagaaatcg attttactgt
     5221 cctgatcgat ttgtcctgtt ctcatttcat tttactatat tttagaagat atgctgtgct
     5281 attccagatt cagttcgcta tacatgcccg tcgtaccaca aaatcccgtg tctgatgagg
     5341 cacgggattt tttagcttct ttactgagat ggattttcct ttttagttcg tgccaatctc
     5401 aaggcacgat ttggattgag acgattaaat agttcttcca atttcttttc attccaaacg
     5461 tctgcggcgg aaacaaaatt accatccgca tctcggaaag atatcggttt atctcccata
     5521 ccagtctcct agtctacaaa ttcaaactca aatttaccaa tgcggaccaa atccccatct
     5581 ttagctccac gcgcacgaag ggcttcatca acccccatac cacgaagctg acgggcaaat
     5641 ttcatgacag attcatcacg atcaaagttg gtcatattaa agagtttcat gagtttttca
     5701 ccagaaagta cccatgtcgc atcgtcatca cgactaattt caaaggcttt ttcttcttcg
     5761 tcaaatccat agtaagcttc ttcttccata tcggactcgt cgtagagcaa aaattctggt
     5821 gtcttgtcta acaattcagc tgtagcatct aaaagtgttg ccagaccttg cttggtcaat
     5881 ccagaaattg ggaagatagc tggtaactct tcaaattcat cataattttc agccaatttt
     5941 ttcttaaagt cttcaatatt ttcctgactc tcaggcatgt ccatcttatt agctacaata
     6001 atctgtggac gctccatgag gcgaagattg taagactcca gctctttatt gatagctagg
     6061 taatcctcat atggatcacg gccttcgcta gctgacatat caatgatgtg aaggataaca
     6121 cgtgtacgct cgatgtgacg gaggaactga gttcccaaac caacaccttg actagcccct
     6181 tcaatcaaac ctggcaagtc ggctactgca aaggattcac ctgattgggt gcgaaccata
     6241 cctaaatttg gtacaatagt ggtaaagtgg taggcaccaa ttttaggctt agctgaggta
     6301 ataacactta aaagtgttga cttccctaca gatgggaatc ctactaaacc gacatctgcc
     6361 aagattttta gttccaattg taactcacgt tcctgacctg gttctccatt ttcagagatt
     6421 tccggtgcag gattttttgg tgtcgcgaaa cgaatatttc cacgtccacc acgaccaccg
     6481 tgggcaacga taaattcttg cccatgttca atcaaatctg ttaaaacctt gccagtctcc
     6541 gcatcacgaa cagtcgtacc ttgtggtact cgaactctaa ggtcctcagc accacgacca
     6601 tgcatccctt tggtcatccc tttttcacca gaatcagcct tgaaatgacg attgtagcgg
     6661 aaatccatca aggtacgtag tccttcgtct acaacgaaga ccacattgcc tccacgacca
     6721 ccatcaccac cccaagggcc tccattaggg acatattttt cacgacgaaa ggcaaccata
     6781 ccatcgccac cattaccagc cttgacctta atcttagctg tatctaaaaa catactcatt
     6841 atttcttctc actttaaaaa agggctggga aatcccagtc actaaatttt cttgaatcta
     6901 ttttatagat tactgagggc accaattgca gttgcaaaaa ttcccaataa acttgctact
     6961 agcatgataa tcacgataaa caaggttatt ttctcaaaca tagttttttt acgatttcca
     7021 ttatctccaa atgccatttt tctctccttc gttacattct attttctatt atcttagcat
     7081 gaattgagct agttttcaat agtcagttgc tactggtgcg ataatccata aaataatgta
     7141 agctacaatt ccagctccgt aacagcaagt aagaacaccc caaatgactt gaacgatagt
     7201 cggatccata tccagataat gggccacccc agcacaaaca cccgcaatct ttttatcacg
     7261 accgcttctc attaattgtt tttttcatag ctgttcctct ttctattctt catggtcttt
     7321 ccaatagtct ctcatactga tcaactgtgt ttttgaagcc ttcaacatgc gtctagatcc
     7381 ttttacaggt acagcaacca cctgttgctg aagatacaaa actgtcttaa agatacgctg
     7441 actgaccgta tcatctttag ccaaatcttt ctggaagtta tttgaaataa tggcatccag
     7501 ataaaactca tgcactcgtt tcccaaagtt ctcagctgaa atctcataca atttctctga
     7561 taaggtatgc tcgttcatgt ctggtgttgc aatcagggct tccaaaatag caccagccaa
     7621 atcatgttct ccatagtaca aggttccaaa cattttatca ctgatgaggt tgttcaaata
     7681 aggatttccg tgagcaatga caggtgttcc actggctaag ctttccaagt aggtcaaacc
     7741 ttgcgtttcg cttgtcgatg ctgaaatgaa gaaatccgcc gctttatagt aaagagccgt
     7801 ctcactagga gcaatcatcc ctgtaaagat gactgagtct tgaatctcta ggttctgggc
     7861 ttgctctttg aggtcattca gataagggcc atccccagct actaccagtt taaccttgtc
     7921 ttcctctttc agaacatcag caaaggctgc taaaactgct tgaatatttt tttcatagga
     7981 gattctcgaa agactaagca acgtcttttc accatcttga atccctagtt tactacgcag
     8041 ttctttcaaa ttttcctgct tgatttccgg acgctcaaac ttggctaatt caatcccagt
     8101 aggaatgacc cgtttttcaa ccttgacctt ataatcagat agcaagtcac ggacaatctc
     8161 actagggcaa ataaccccat ccacatcatg caggaaacct ctaaccagat acttgaccat
     8221 actcggccgg atcaacatcc ccttagcaat ataatggaca tagtcttcat actgggtgtg
     8281 ataggtatgg atgactggaa ttttcaattc acgcgcaatc caaatcccca acaggccaag
     8341 agaaaattct gtctgagtat ggataatatc tagctgatac tgtttagcaa tttcaagtgc
     8401 cttgctaaaa cctcggtagg caaagcgacg atccttaaaa gcaaagaaag gaacacttgg
     8461 aatgcggata atttgccaat cttcgtagcg attgacatcc ttatctgtcg tcgtaaagat
     8521 aaaaacagca tgtccctgct tttcaagttc tgttttcaag gttcgaatac tggtcgcaac
     8581 accagaaacc tgaggaaaat aggtatctgt aaataaacca attcgcatag attacctcac
     8641 tttttacttt ctccctaaag cggcttgttt ctcataaaaa tccaaccaga tttgtaacag
     8701 atgctcttca gaatactctc tggaaatatt cttagccttt tctttgagat cttttaaggc
     8761 agcaggattt gcttgatatt ccaaaatagc ctctttcatc tcttctctac ccgctgtcgc
     8821 ccgataattt ccctccaaaa tcaccttata gagatctaaa tcacgcaaca taataggagc
     8881 ctcacaactc gcagcttcta aaatagtcat aggaaagagc tcattgtaac taggcaacaa
     8941 gaaaagatcc gctagagcat acaattcgcg catccgctct ggcgatacaa tgcctggaaa
     9001 aatcaaattt ttagggggat tttccataat tttcttatag tgttcataac catctgtcat
     9061 accaccaaaa gagaagccac cagcccagat aaaggtaatc tgaggcaatt cctcagccag
     9121 acggataaag tcatcaatcc ctttacgttt ctgaacttgc ccagcaccta ctacgataaa
     9181 ctgattgtca ctaagaccaa gatctgtgcg cagtctgact acctcttctt gtggtagagg
     9241 atgccatttt tccttgttga caaagttagg aatataggtc actttttcac gtggaatacc
     9301 agctgctacc aaatcctcaa taaacatagg attgaccaca accaagtgct ccatccggtt
     9361 gtaaaaagaa aatacatagc gtttcacaat tccctttaag aaaaatggaa ttttcaaact
     9421 tccctcaagt gtagctggca agaaatgcac atagccaatc tttctccctg agcgtttctt
     9481 ttggaaggtt gataaataat agggaaaatc aatcgtatga aagtgagtca catctgcctc
     9541 gattggaaga ttttctgtaa caatcaattg gtccttggca gcacggtgaa gaagacgaac
     9601 taattcacgg taagcacctg aaactccctg tcctgctact ttctcacttg aactcaacat
     9661 attgatgcgt aatttctttt tctccataac tactattata tcattttctt tgaataaaat
     9721 cagcaaaaga aaggagagac tagaggaaaa gaggggaaat ttcctcgctt ttccaacagt
     9781 ctctcacatg cttttatatg tttacttaat gcctagggca atgcgggcat agcgactcat
     9841 tttttcaact gtccaggctg gataccagac taatttaacc tcagtatccg ttacttctgg
     9901 aacctctatc atagcatcat aaatctggtc tgtcaaaagg tctgctaagg gacaacccat
     9961 agttgtcaaa gtcatgtcaa tctctgtttg ccctgtgtca ccgtcaaaac gaatctcata
    10021 gatcaaacca agattgacaa tatcgattcc caactcaggg tcgatgactt cttccaaggc
    10081 tgttaaaatc cgtgttttga tgttttcaat ttgctcttct gtataagcca tattttcctc
    10141 actcttagtc ttcaataaaa tcacgaagcg gtttgctacg acttggttgg cgtagttttc
    10201 tcaaagcctt tgcttcaatc tgacggatac gctcacgagt tacgttaaag actttcccca
    10261 catcttcaag tgtgcgcatt tttccatcat ctagtccaaa acgtagacgc agaacatttt
    10321 cttcacggtc tgtaagagta tctaagattt catccaattg ctcacgcaag acgatacgag
    10381 tcgtataatc cactggattt tcaatcactt catcttcgat aaagtctcca aggtggctat
    10441 cgtcctcttc accgatagga gtttcgagag atactggttc ttgggcaatc ttcaagattt
    10501 cacgaacctt atcaggtgtc atatccattc gttcagcaat ctgttctggt gtcggatctt
    10561 gccccaattc ttgaaggaga ttccgctgtt cacgaaccaa tttattgata gtttcaacca
    10621 tgtgaactgg gatacggatg gtacgagctt ggtccgcaat agcacgagtg atagcctgac
    10681 gaatccacca agttgcataa gttgaaaact tgaacccttt agaatagtca aacttgtcaa
    10741 ccgccttcat caagcccata tttccttctt gaatcaagtc aaggaactgc ataccacgac
    10801 cgacatagcg tttggcaatg gaaacaacca aacgaagatt ggcttccgca agacgttgtt
    10861 tggcttcgat atcaccagct tcaacagcca gtgccaactc tttctcctct tcattggtca
    10921 agagaggaac gacccctatt tctttcaagt acatacggac agggtcattg accttagcag
    10981 aagttgaccc aatcaagtcc tcatcgctga gttctggttc ttcttcattg ctaagaacac
    11041 gcgcacttgg atttccttcg ttatctgtga tagaaattcc tgcatcctga atccgttgca
    11101 agagatcttc aatcccatca gcgtccaagg taaaaggaat aaccaaactt gcattgattt
    11161 catcatctgt tgctgtccct ttttgcttat gattacggat aaattctgct acctgtacgt
    11221 caaatgttgt tacttctttt tgttttgttg ccattattac tccattcttc tcttttggga
    11281 aattaaacgt tccaattctt ctagggctgt atctgtatct cctacatggc tagcttcctg
    11341 caccttcttt ttgattctca tattgtcctg attcaagaga gccttgtttc gagtcatctc
    11401 tacttcacta agttcctgcg gcgatatctc agcaggcaaa tcctgagtta aaacttggta
    11461 ccaagctctt tcaacttcct ctgtctgctc tgctaaaact tctggaggaa gatttccata
    11521 ctggccaagc aagtcatata agacctgaaa ttcaggtgta gcaaatgcaa agtcttctcg
    11581 caaacggtaa tcgttcaaaa caagagggga ttccatcatc cgatagagta gatgggcttc
    11641 tgccctcata atagccgata actgcttggt gataggcatg gtgattggcg tcggtctgga
    11701 aattccttcc atgcgattct gcctttgcac ctgacgactc tcattaacaa tctgctcaat
    11761 ctgggtataa tcaaaggacg ccagactgtc agctaaaata tgaatatagc tgttttgagc
    11821 agcgatggac ttttcttgaa caatcaaggg agctattttt tcaataaact caatctgagc
    11881 ctgcagattt tcactgtttt caggtttgta ctgatgaatg tagaactcaa tcggactaat
    11941 acgagttttt gttaatagat aggccaagtc ttctggacca tttttttgta gatactcatc
    12001 aggatccaag ttatcaggca tgctaacgat ttgcacaggc atatcaccaa tttcatccaa
    12061 tgctttcaat atcgcggctt gcccagcctt atctccatcg taaacaagaa ccaatttctt
    12121 ggttaacctt ttcagatgct caacatgctc tcgactcaag gccgttccca tcgacgccac
    12181 agcattttcg attccagccc gataggctgc aataacatcc atgaatcctt ccatcaggta
    12241 aatctcacta gcttttccag aagatctttt tgccctatcc atatgatata attcgtaact
    12301 tttgttaaaa attgcagtcg atcggctgtt tttatactta gaagtttgtg aatccgtttt
    12361 ttgccagata cgacctgaga aggcaatgac ctttccttgg tcatttgtca ggggaaacat
    12421 aatgcgattg tgaaaggtgt ctacaaattg attggcatcc gagagataaa acaggcctga
    12481 atccagtaaa tcctcttcac gatactgatc agacaaacgt tgatagagat agtttcgttc
    12541 tggaggtgct aaaccaatcc aaaaatgttt aagcacttca tctgtcaaac cccgctgata
    12601 aaggtaattt ctggcctctt ctcccatagt cgttgtcatg agaatagcat ggtaaaattt
    12661 ggctgcatct tcgtgcatat cataaagagc ttggtgaggc gaggctggct tctgttcact
    12721 ataaagcggt ttttcaacct caatcccgac acgctgacct aagatttgga cagcctccat
    12781 aaaggtaacc ccttggtact cctcgatgaa tttaaagaca tcacctgagc gaccacaacc
    12841 aaaacagtgg taaaactgct tgtcctctac aacgttgaaa gaaggtgttt tttcaccatg
    12901 aaaaggacag agccctagat agttccgtcc tgccttttgt aaagaaatca catctcctat
    12961 gacttccaca atgttggcat tgtttttgat ttcttcaatg acttgtttgt caaccataca
    13021 caatacctcc atgttatcat agtttacttt atatagtata ctttatttca gaaaaaaagt
    13081 aaaccatttc actcattttc cctactttat tcaaagagtt gataataatc agagattttc
    13141 atttttgctt tttcttcttg gtttaaatct tggataatcc gtccttcttt catgacaatc
    13201 aagcgattgc cgtatttgag agcatcttcc atatgatgag taatcataag ggctgttagc
    13261 tgatctttct taacaaattc atctgtcaat cccatcaaag caacactagt ctttggatcc
    13321 agggcagcag tatgctcgtc taacaagagt aattcaggtc gcttcaaggt tgccatcaag
    13381 agactcaaag cctgtctttg tccacctgat aagaactcaa tcggtgtatt caagtgtttc
    13441 tcaagaccat ttcctacttt ttcaatggtt gcctgaaatt catccttata gctagtcaag
    13501 cgtcgtggta acaatccacg cttttcacca cgaaacttgg cgattaaaag attttcagcg
    13561 accgtcatac ggggagctgt ccccatcttt ggatcttgga agacacgaga caggtacttg
    13621 gcacgcttct cgggtgaaaa cttagtgagt tcttcaccta aaatacggat agttccacta
    13681 gttagtgata aggtccctgc tatagtgtta aagagggttg attttccagc accatttccg
    13741 cccaaaatcg tgataaagtc ccgttcaaaa atttctaagg aaacatcatt taaaataatc
    13801 ttttcttcat caaagccatt tttaacgatt ttggttgcat tttttaattc tacaattgct
    13861 gtcatttgct taacttggct cctttcaaga ttgtttgctt aaatattgga atcatgaggc
    13921 agactgctaa aatcaaggca ctgtataaac gaaggtaact tgtattaaag ccaagtgcga
    13981 taactgccca cactaaaaat tgataagcga tagaacctac aacgatagta accaaacgct
    14041 ctgccaagct caaactcttg aaaataactt ctccaataat caaacttgca agtcccacaa
    14101 cgataacccc gatccctcga gacacatcgg catagccttc ttgctgagca atgagggcac
    14161 ctgcaagggc aatcacacca tttgataaga ccaagcccat gagctccatg cgtccagtat
    14221 gaatcccgaa acttctagcc atatcaggat tatcccctgt agcaatatag gcttgtccga
    14281 gtttagtgtc caagaaaaag agcatgagag caataacaat gctcacaaag atgagacctg
    14341 tcaagagttg attcaaatcc gaatcaaaag gcaaaacatc ctgaatttgc ttggttccaa
    14401 gcaggcctaa atttgcacgt cccataatca agagcatgat tgagtgacaa gaagtcatca
    14461 ccaaaatccc tgagagcaag gttgggatct tcccttttgt ataaagaagg cctgctgcca
    14521 ttccagccaa acaacctgct cctacagcaa caagtgtcgc taaaaatggg ttcacgcctt
    14581 tggttatcaa agtgacagca acagctcccc caagagggaa ggaaccttct gtcgtcatat
    14641 ctggaaagtt taaaatccta aatgtcataa agattcccag acctagaata gcccagacaa
    14701 atccttgaga aataatggaa acaatcatat tttatttaat cctttctata ttcatctttt
    14761 taaaaaatgg gaagagtctc ctcctcccta ccttatttat tcgatgactt gtcctgcttc
    14821 tttgagaaca gactcaggaa tagtaatacc tagttcttgt gctatttttt tattgatgac
    14881 tgacttacca gttgaaaaga cattgactgg ggtatcggct ggttttgcac ctttcaagac
    14941 ttgcacaatc attttacctg ttgccacacc aaggtcatgt tggtcaatta caactgatgc
    15001 caaaccacct acttctacca tagctgtcgc actgggataa attggtttct tagaactttg
    15061 attgctagag acaaccgttg gaaatcctga tgcaatggtg ttatcaattg gaacccaaat
    15121 agcatctacc ttgctagtca taacagtgac agttgaggca atttcatttg ttgaaggaac
    15181 tgcaaatgtt tccactgtca gacctgcttt ttcagcataa gccttaaatt cttcgacctg
    15241 tgtttttgaa ttgtcttcgc tacttgagta aagagctccg attgttttca cattcggtgt
    15301 cagagccttg atgagttcaa tttgttgttg agctggattg tggtcagata cccctgtaac
    15361 gttgccacct ggttttttca aatctttaac caagttagca ccaattgggt ctgtaatagc
    15421 ggccatgata actggtaggt cttttgttgc actagccaac ccttgggctg ctggtgttgc
    15481 gataccaacc acaaggtcat tcccatttgc aaccaattgt ttactcattg tcgcaacctt
    15541 actttggtca ccttctgagt tcataaaatc aattttaact tgatcatctt tatatccttc
    15601 ttctgcaagt ccatcttgga tccctttata aatcaaatca agggatggat ggctcacaaa
    15661 ttgaagcaca ccaatcttag ttattttctt ctcatcctta ttattctgag cttctgattt
    15721 attcattgaa gaataaatca agcttcctgc tactaagact gctaatgcag caataattcc
    15781 aattaaacgt ttatttttca ttctgtttct cctttttatt tcctttaaca tatttcactt
    15841 atctaaacaa gcgacgccat tgttttcttt ccatactaac ctccatcaaa aaaatcctca
    15901 cacaaaaaac ttgtgtgagg acgtcgatgc gcggtaccac ctcaattata gggaatttcc
    15961 ctatcgctca gtctcgcaat aacgagatgc actgtaaggt gtgcttaccg aatttttata
    16021 atttcaaatt ctaaatagca ttcagcccaa ttttcatcat tgccacttat ctgttttcag
    16081 ctaccacaga ctctctaaaa agtttgtatg attacttttc tgaatggtta aattatatca
    16141 tttttaaact acttgtcaat agtctattag aatttttttg atattcactt ttagcattca
    16201 ctcttgaaaa ttatcaacct gaattacgca atcctgtcgc aattccgttg atggtgatat
    16261 gaatcaatcg ttcttgatca ctggacaatt ctccacgacg ttggcgttta atcaactcta
    16321 actgaatata gttgagaata ttaaagtaag gcatacggta atccagacta gcttttagat
    16381 atggattgtc agctaagagt tcgtcatgtc cttcaatagc caagataacg ttcttagtaa
    16441 cttgccattc atttaaaata gtctcataga tggccttaac ttgctcgtct tcacaaagtt
    16501 tagcatattc aaaagcaata ttcatatttg attttgacaa aaccatatca acatttgaaa
    16561 gaagcgattg gaagaaaggc caattttggt acatatctcg taagatagca atattctctg
    16621 gatttttatt gataaattcc ttgaagcttg aaccaacccc gtaccatcca gggaacataa
    16681 cacgactctg tgaccatgag aatacccaag ggatggcacg caatccaccg atttcagtaa
    16741 tagtcttacg agcggctgga cgagaaccaa tattaaaact tgaaatagcc ttgattggac
    16801 ttgactcgaa gaaataatca tagaaatgct cattaccaaa gaccaaatca cggtagatat
    16861 cgtaactacg gtccactact tgatccataa tggcttcata acgatttggg gtattggtat
    16921 cgctcttctt ctgagtaatc atacggttaa tagctgccga tactagcatt tcaaggttat
    16981 agtaagcggc gtctttgtta ccgtatttat tcccaattac ttcaccctgc tccgtcaagc
    17041 ggatacgatc cttgatagac ttgagcggtt gagacgtaat ggcttcatag gttggcccac
    17101 caccacgacc gacagtacca ccacgaccat ggaagaaggt aaccttaacg ccaaattcat
    17161 ctccaatagc agtcaattgt tgttgagcct tgtagagggt ccaacatgat gacaagtaac
    17221 cgccatcttt attactgtca gagtagccaa gcatgatttc ttggtagtta tttcgtgagt
    17281 caatccattt tttggcaagg ctaagagaaa gatattttct cattgtttcc tctgaatgat
    17341 ccaagtcttc aattgtttca aaaaggggaa caatctgaac acgcgccctt tccgtatcca
    17401 ccagtcctac ttcttttaac agaatagcta attctagcat atcagaaagg ctggttgcat
    17461 gtgaaatgat ggtctgacgg atgacatcat ctcccaactt atctttcaaa acacgagccg
    17521 tcttaaaaat agctaattct tttgctaata attctgattt ttctgcgtga gtcgcagaaa
    17581 gaattcgggg atcttcttct aattctttca agagaaggtc acacttttct tcttcgctca
    17641 actcgctata acgagaatga attcctgctg atttcaagag ttctgccaca caggcttcat
    17701 agacgctaga gtcttgtcgc atatcaattg atgctaagta aaaaccaaat atctctactg
    17761 cctgcaataa ttccacaaaa tcacctgaaa tcaaggactc gcccttattt tctagtagag
    17821 aatctcgaat ggcaatcaaa tccttgtaga aatcattggc ggtttcataa cgagtcccaa
    17881 cttctttatc ctcaatcaga taggttttag ttgcctgaat ttttgattga atatcaaaca
    17941 aggcacgacg gtaaagctct ttttcgcggt aaatcgagtt atccttggat tgacgagcca
    18001 tttctctgac ttgcttgctg acgttgacaa tgctagttga aagagaaaat tcacgataaa
    18061 gttggtaaat ctttttatca tagtagttca tgatgacttc acactgagtg agtgcagact
    18121 gcttcaaggt ctttgctgta acaaatggat ttccatcacg gtcaccacct atccacatac
    18181 ccatggtgat tggtttagcc tgttttaaat tcagaccatg cgcttgcgct aagcgcttat
    18241 actccgtcgt caaatgaggt acagctttca aaaaggagct gttataatat tccatagcat
    18301 tcgtgatttc gttagtcact tttaattttt tctcacgaat catgtctgtc tgcatgataa
    18361 tttcgatgta acgacgcaaa tcattgtacc atttatcttt attgatcaac cccaacttaa
    18421 catcacggta tttacgcaaa agactatgaa tatgatttgt taaatccaac atacttttgc
    18481 gttgcacttg tgttggatgg gctgtcaaaa cagggacaac attcaagtgt tctaggatct
    18541 caacggcatt ttccttttct gctaccaatt taatcgttgt agataattta cctaaatagt
    18601 cctgatcaat attattttga tgattgattt cataagctaa atccacatcc tctgaaatat
    18661 taatcaaaag aggcaagata gagaaatagc gtgaaatata gaccatttca tcatttgata
    18721 agctagtcac tagacggttt agaccttgat aatcttcctg cgttgataat tctttcaact
    18781 gtattatttt ttcaaaggtc tctggggcaa gcatattttt agtaatatct tccagtaatt
    18841 ctgttagaat caagacttct tcttgcacaa cacttttatt actataattt tctaattttt
    18901 gaagagacat aaactatcct ttctttatcc tacttcaaca gaaggttcat tggttgattt
    18961 tccaattctc ggtacaactt agcgcgtttt tcactggcat caatatttaa gacaaaggct
    19021 actgccactg ataagactag aagactattt ccaccctggg ataagaaagg gaaagtcact
    19081 cctgtagatg gaatcaagcc cgaaatccct ccgatattga caaatacctg aaccaacatc
    19141 atccctccga caccgagtgc aaccatggca ttgaaaggat tctccgctcg gataccgacc
    19201 aagataatcc gcaaaatcat gaaaaacaag agagctaaaa taagactggc accaacaaag
    19261 ccaaattctt caatcacgat agaaaagaca aagtctgtat gagcttctgg caaataacct
    19321 cgtttttcaa tcgagtttcc aagacctaga ccaaaccaac caccattgac catggcaaaa
    19381 taagaattag ctaactggtg acctgcatca gcacgatcgg caaaaggatt aaaaaaggca
    19441 ctaaagcgct tggctacata gccaaatact ggaatttttg aaaaggtctc aacaccgatt
    19501 aggctgatag tggtcaagac aaagacagaa gtggcagata cgagcgccag aatggttgaa
    19561 aaccagcgat aagcgattcc actaactgta tacataatca aggaaaccaa gactaaaata
    19621 gtcgcatttc ctaaatcagg gaaaattccc aaacttccaa tcagaactag gagaacgaat
    19681 cgccaatcat taaaagcacg gggaagccat tgattttgag tcaaaacttg aaaatcataa
    19741 gtagctattt cttcttgctg tttggagaat cggtgagcta aataccaaat aataatgatt
    19801 tttaagtact cagctggctg aatagttact cctgcaaccg aaatccaacc gtatgccccg
    19861 tttactgaaa taccaataaa acgagccaag aacaataaaa gcatttctat taatataact
    19921 aaaatgatta gtcgctcatt tctcaaaaaa tctagtctca atttataaat taaggcaatc
    19981 agtatcaaac taacaatcca aaagattcct tggtttcgaa ccaactgcaa ggcgctcttg
    20041 ccttcttcaa ttaaaatagc actggtggtc gaatagacca caatcaagcc caaaatagat
    20101 aaaagcaagt agggaatcaa gatggaataa tttaataagt gcctcttact aatcttcata
    20161 gtatcaccac tctactagga tacagacaaa tctgttccaa attccgtttt attttctagt
    20221 tttgattgct attataccat tttttcagaa agaaaaaaac tcttacctta caatccttcg
    20281 aattttactg tttttacaga attaaggcag aatttgaaat cgtaaaacca ttttgaataa
    20341 gagttgcttc aacccattga ctccgacgaa ttaagttgct ttcgtgaatg ccaaaatcag
    20401 ccgcaatttg ttcataagtg ctctattctc gcatgtattg aatagttacc ataaggagat
    20461 cgtctaggct taatttgctt tttcgtccac cttttgcgcg tttacgttga taagctgttt
    20521 ttaacacagc taacatctct tcaaaagtcg tgcgctgaac acctacaagg atcttgaaac
    20581 ggctatcgct taattgttta cttgcttcat catccatagt tttattgtat tgtatttttg
    20641 tttcgcagga agtctattat tcctttcgtt ccaaggtttt tacgctttta gcaacaagct
    20701 tacacactga gcgtttcgga cttaccatat catttcgttg gagattttat catcaatttt
    20761 tagattaaaa aaaatttccc aatcttcaca aacttctgta gcaggaattg tatgaatctt
    20821 tctaagtatc tttgtatctt tcctgcttct acaccatatg tgtattgttg gttttctgaa
    20881 taagctaaaa tgctatctat tgcatctctt ccgtctatcc attcgtgtaa agaatgtact
    20941 tcgtcatcgc agagttcaat gctaattggt ttacacatcg gaactccaag agaagctact
    21001 ttctccatca tatcaaattc aaattttttt ataatctaac ttcgacttat cagaaacacg
    21061 caagaaatat ttttactgat tttgatctgt cacacaatat tttttatcat ctgaccagcc
    21121 tttatttatg gctatcttac tactaaaatc catcaagcac actccgattc actttacaac
    21181 actttttgca gttttcacta gtaacctatc cagttcgtct acacttttat ttcctagatc
    21241 catttttaca ttatgaaagt tagtcaattt tctctatgat gtttccaagt ttatccaata
    21301 caagacaaga atgatcattt agtggaatta tgggaacatt aacgagttct tcagctctat
    21361 ccttatttgc tttatcattc caggaatcat aatggacact aattaaaaac tgactaaaga
    21421 gtcctaatcc attttttatc tttatctgat gatctgaatt atcattaggt gagacataga
    21481 ctttttctcc taatagtagg gctcctgcag aaaatcctat aatttttgcc tctttattaa
    21541 gcatatgatc gatataactt ttgaactcct gattaacata agtagcaata tatttttccg
    21601 tatttccacc accgatgata attatgtcag catctagata gctatcaaga tcaatctgct
    21661 cagtgtccag gagcaagtaa tcaatgttta gattaggaaa ttgactttga aaaacttccg
    21721 tgtacttttt catgtacggt tcccaatttt ctcgaaaaac tgtaaaaatg ataattcttt
    21781 taatcttggt tgataataca attttatcaa caatactata tttcttcatt gggggattcc
    21841 cacccatcaa aaaaatttgt tctttcaagt taacacactt tctaaagata cataaagttt
    21901 aaacaagttt attcacgttt ctaaattata attttttctt aaaatgaata attctatttg
    21961 cctcctgaaa tccaatattg agatgaaatc ttatagaatc cgtattcgtt aaagtacagt
    22021 cacttgcaaa ttccttacat cctttatttt tcgcacattc ctcacatttt gtacagagat
    22081 ttttagcaat atcctttaaa cgatattcct cgtcaacaat aatcccttct aagaatccaa
    22141 caggactata tttacaacct tcaacataat caaatctgag tgaacatagt gctagaccta
    22201 caattgtgtc accttcaact tcagtaaaga ttgcagtatt tttgccattc gtatattttt
    22261 tacttcatca atagcttctt tatcggtcaa ttggggccat aattgtttca ttagtttagc
    22321 cgtttttata aaatcttttg ttattccatc catattgatg ttcctccgca aattacaagt
    22381 aaatgtttcg aatcatgctg atactttgtt actcattgat tgataccaat tttatactgc
    22441 tttcaaaagg ctcatatgtt ttatacttaa ttacttcgtc tttaaaatta aataaaggtg
    22501 tatccggctt agcattccat aaaataatca accacattat agcattataa agctgctttg
    22561 cagtttcatt ccacttttca ggttgtaaat ttccactccc tgtattgtca tattcttgtc
    22621 tattatttac atgagaatca cctacaagcg gattaaaaag aggtagccct ttgtgattaa
    22681 ttagttctaa aaaatccctt gccgcaccca tgcaacactg aataacttcc ttcttgtcat
    22741 caattttact ctcagcgata aatacataat attcatcttc aatagttgct cctgcatcac
    22801 tatgtttttg ttgatttgct aacagcttaa tatgtgcttt aggctaaact tcaaaatctc
    22861 taacaattct ttgtcttgtt tcatgtcctc tacaattcat ttaagttctc ctttacaagt
    22921 ttagtaacta gccttattat actatataag atatgaaatg taccataatc ttcatcaact
    22981 agtttttaga aaatcacaaa tccatctgga gagatgacaa gctgattctc caattcttgg
    23041 caattgcttg ctagtgctac tgcttctttc tctaaaagat aatcttctgt tgattggttg
    23101 aatattgctt tgaggatccg tccttcgtat ttccattcca gagctactag atcagatttg
    23161 atttcttgaa ggctatactt gccatgcgaa atgattactg acgcgtattt ccgaatctta
    23221 atcagcctct tcataaagtt cagcatatca ttgtcacttg atacacgttc ccaaggcata
    23281 caacgacgac aatctggatc tggtcctcca gtcaaggcta actcggttcc gtaataaatg
    23341 cacggtgttc ctttttgtaa aaagagaaag gctaaggctg atttaaccag ttgaacatct
    23401 tcattggccg tccacaggat tcgctctgta tcatgtgaat ccaagagatt aaacatgacc
    23461 tctgaaatct gctgcttgta atacatagac tctccattga tttcatcgat gaactggtct
    23521 gtcttcttaa ttcctcgtaa gaaatagtcc ttgatactat cagataaagg ataattcatg
    23581 acggcatgga actcatctcc atttagccaa ggctgagatg tatgccagac ttctcctagg
    23641 atataaagat caggattttt agctaaaact gccttacgaa aatccttcca gaactgatgg
    23701 tcaatctcat tagccacatc caaacgccaa gcatcgatat taaactcttc aatccaataa
    23761 gtcgcaacct ttaaaagata attcttgacc tctggattgg ctgtatttag cttaggcata
    23821 tagtcctcga aaccaaaaac atgatagggt aagtctctct tattaactag cttttcagtt
    23881 gtcactggga attgttgaat atggaaccaa tccttataag cagactgttc accatttttg
    23941 acgacatttt tccattgaag agattgcgaa ccaatatgat taaataccgc atccagcatg
    24001 actttcatgc cacgatgatg cgcttgatcc accagttccc gaaaggtctc cttgtctcca
    24061 aaatgacggt caatttcaaa gtaatctgtc gtattgtact tgtgattgct tgtagattca
    24121 aagatgggac aaagatatag tccagtaata cccaagtctt gcaagtaatc catatgatca
    24181 ataatcccct gtaaatcacc accaaagaaa tcatcgctct taggtgtgac agatgaatcc
    24241 cagtctaaag tcccttctgg gtttaataga gcattgccat tggcaaatct ttcaggaaat
    24301 atctgatacc ataccgtatt tgaaacccag tcaggaatct tgcaggcatc aatctcatga
    24361 agataaggca acttaaatcc attcccaatt gcatgaagat tttctagaga attttccaca
    24421 caccctttat cgccatacaa aatattttga ccttctgtat ctctgagctc aaagagatac
    24481 tggatacgtg caaagtcaac tgacacttca acctgccaat ggtcaaataa ggtaccagaa
    24541 gttatcttga ccatttcttt tgtatcctga taaaactcct ccataaagat aaaagggtcc
    24601 ccatagtgca agttgatgct ttcaatgtcc cctttcttag ttcgaattcg aatatggagt
    24661 ttcttatcct tataaagata ggcatactcc gactcaggcc tatggtaaat agcactcaat
    24721 tccatcaatt tgtctcctaa agtattcatt caaattttac gcaaacgttt tcaaactcaa
    24781 taaatccagt atactatttt tgtgaactat ttgcaaggaa tgtccgttgt taaaggaact
    24841 atcttttaaa gtatacaaaa agccttaaaa aaggctttct ctatatacta atcctctttc
    24901 ggttttgaaa atacttctac tcgctgagct aggactttga tttctacagg taggttatct
    24961 gatttatctc cgtcaacatc tgactccaat tcactatctg aagagatttt aatattacgc
    25021 gctttgatat actcgatatt atcatttgcg acaacatccc cttttaataa atcaggaatg
    25081 acggataatt tggagaatat agaggcatct ttcagaatca aaatgttggc atagccgtcc
    25141 ttgttttctt caaagatttt cttatcagcg aagtaatttg tcaaaaggac caaaacatgg
    25201 ctagcttcac caacataatt tccattttct gtctcaacct taatgttaaa gacctgatct
    25261 gtcatgacag acttcatggt atttacagca taggttaaaa taccgaattt tgttttgtcc
    25321 tctatttcaa cattgtgaat cgcctcaggc agagaaccga tactaaagat ataaccaaaa
    25381 tagttgtcat ttgctttacc gatatcaatc ttattggtta aatcaaaatc cagttcgtca
    25441 attgcgccat cgatgtcttg attgatttcc aaaagttttg taatgaggtt acccgtaccg
    25501 cctgggataa tccctaactt aggaatgtag tctctctcat caatacctga aatgacttca
    25561 ttgacagttc catctccacc aaacacaacc actgcatcat actgctcacg agaagcttct
    25621 tcagcaaaat gtgttgcatc cagcgctttt tcggtaattt tggtttcaac atattcaaag
    25681 tattcttttg ctttattctc cagcttttct ttgtaatcca aagccttctc gccaccagaa
    25741 gtagggttga taattaccat tgcttttttc attgatttta tccttaattt taaacagaaa
    25801 tgtttacatt tcgtcgtatg caagtaaatg taatcctatt atacaatgaa aatacagaaa
    25861 agagaaatct gacgtactgg agattaatac gcttttattc tattttccca tcgcctaact
    25921 acatccttta agggttcatc caagtaagaa taggccttat ccttgatcca atcaggaata
    25981 ccgtaagctg cctctgctat gctacaagtg attgctgcga gagtatcact gtcgccacca
    26041 agtgagatgg catttcttat cgcatcttcg aagtctctac tttcaagaaa ggcgataatg
    26101 gcttgaggga cagtttcctg acatgtttcg ttaaaacgat agttaggacg gatttcatct
    26161 aaagtttgag atagattgta atcgtattct ttttctatat aatccttaat tcgtctttta
    26221 cactctgtag gattgtcgtt aattgattgc tcgtactctc tacaataacc accaaagtaa
    26281 aaacgacata gaaagatagc atcagctgta gccatagcgc ctttgacacc ttctggatga
    26341 ttatgagtta cctctgcaga aagactcgta agtcctctag atgatggcca cataccagtt
    26401 ttcgcataaa aaccacagtc catgatccaa gcacatggag aaatacgcat agctgatcca
    26461 ttcccaaagc tattataagg ctcacggtta tcgctgttta gccatgcatt aaaccgagca
    26521 ccgtaatcag cattcggata cattctgcca tatttcttca tcgcgtcaat gaaatcgtct
    26581 ttttgtccac cattcataat tgcttctgca acagcacagg tcataaccgt gtcatctgta
    26641 aaaaagcagt ccttccgaaa taaaggaaag tcctttgttt tgatattgtt ccattcgtaa
    26701 acagaaccga caatatctcc aataattgct ccaagcatca gattcctcct tgttcatttt
    26761 gatgcttttt atattggtta tataccatat ttattttaga aaacaacatc ctgttggatt
    26821 ttaaaaattt catttttttc aaaatagggt tttaccattt ctttccacct agctctatga
    26881 aaattgattg attttaaagg agataggcca taatttccca atgcataacc atcatttact
    26941 tcaacaacaa gtgttctgcc atcgcgagta acaccgatat ctagtccata agctattggc
    27001 gcatctttcc aacatgatat cgcttcatca attacacttg catcaaattg tgcatgataa
    27061 tcacctgtat agggtcgaac atctaatacg cgaccatcta acacaaaaca acgccattca
    27121 gctatgaatt ctacaacctc actaatccat ataggatagt cgaaaggtag accaatacct
    27181 attaaatcat gggttccatt aacaactctt ccagtaaaga cttttgaacc agctttaggc
    27241 ttaataaatt ttccccaatt atcaggtata ttcacaatct ctcctaaaat accagcataa
    27301 atctttcgac cataaaactc tttaagctca ataggatagt catgaaccgg aacgtttaag
    27361 cccatcattt ttagtaatgc tctagtctcc attatataat ctacaactat atcttcactt
    27421 gttaactctt ttatttcaga aaaagattga tataaaacag cttcttctcc ttgtaagtag
    27481 gcacctactt gagcattgta tttattaatt gaaacctcac ttggtaattt actttgtcta
    27541 atataaacaa ccatttcatc actcctatat cactagtgtt acaccaattt gtaaaaaata
    27601 atagcaattt tgctcttatt tttttgagta aatagccccc ataatatcat cgaaataatc
    27661 aacggtattt aggagtaatt caataacctg ggactttgtt agtcgcattc cccttctatc
    27721 tctagcatct tctactaaat tttcaagttt ctctagattt ttatcatcca agctaatcat
    27781 tattctattt ttatcggttg ccattttcat cacctcaagt taattctatc acaggtgtaa
    27841 cacttgtgtc aactggcttt tataatacat tagtttaaaa gtggagagga tttttaacac
    27901 agtaacttta aatctttggt attaaaaaat tttcacaata tttatagaaa taaaatctgt
    27961 ctcaaatcag ttatcaaatc tagtataaat tatgagcggc tactctaata ctttccctct
    28021 aaacaagaaa aagacttaca ctcaagggtt ttcttccccc cttcgttata acgttttgac
    28081 tcttttacta gcaaaggtat atactcacaa ggaactttgg ttgactattg aatctctcca
    28141 acttcttctt taacatatcc ttctacatct tcaatctcta caaacattgg gtctaagtga
    28201 cacaagaaat gccaaacttc gatccctttt tttctgtaaa gaatcgcttc accgtcttca
    28261 cttccgaaaa agcttctgtc gatttcatat ccgcggcttt ctaagaagtc ttttgcttta
    28321 cgatagttcg tttctcttgt ttcgacatag gctttaactt catggttgtt aacgacatat
    28381 gcatcaattt ttgaatatcc ttcgatcact ctatcatttt tgagggataa atttgaaatc
    28441 tctttccaaa taatgtttac attttcctca ggatcgaaca taaatttaga taaaggaaca
    28501 atatttccgt taaaaataat ttccatataa tccggtatgt ttttaggatt aaaatactcc
    28561 acttcaaaac catcttctgt ttccagagtg tatcccggga tttgagctac aaaggctttc
    28621 ccatcttcta tggaatcaaa tgctactaaa tctttagaat aatcattttg gtacaattcc
    28681 aatataacca tcgataatct ctccattttc attatcaggc taatgtaaat aagcacgtca
    28741 cctgaccaat tcaggctctc tgtatcatct catcatattt cctacttact ttacgagtcc
    28801 tatacccaga acacacctta tcgaccttcg gtctcacctc gtcgcattgg ctgaacatct
    28861 acttttactt cgctgatgct tcaactcgta caagcagtga taccgcctca gcgtgatgcg
    28921 tcagtgggac tcaaaaggtt tggggaacct tttgaggatt aactacgttt ctctaataaa
    28981 cttacacatt caacttgttc atcattatcc aaacctatgt tgagattttc ttctataatt
    29041 ggtagtttaa aagtaatgga ttttagccat tgtccgttag attgtttttc ttcataaact
    29101 tgaatttcag aaatcaaagc tgaaattaac tgcctacgct ctacatcatt catgacttta
    29161 tagagcttat caaaatagat cagaacctta tatatgttat ctcctgtaag tttttcagct
    29221 tcaatagtct gtttctttgc tttcgcatca attagtgatg attctaattc atctattttg
    29281 tcatacatac gatatagtct atcatctaaa tcctgtttcc ttctcttata gtgcttatct
    29341 tcaacatcta aattatctat ttcctcaatt agcttaaact ttgtagaatg actctttctc
    29401 aattcctttt ggtaattatc tatttctttt tctatttcag aggtatccac cttcatgttg
    29461 attttttctt gcatcataga agcaaatttc ggattactta ctatcttgac aatcacctct
    29521 gcaacagcat catctaacaa ttcttctcta atttgcttac tgaatgtaca cttatgacct
    29581 cttatcatct gcctatgttt acaaccatag taataaaaat ctttatactt tgtgccatct
    29641 ttctttttct tgatacactt gttcccaaac attcccactc cacatatcgg gcattttaca
    29701 attccagaaa gcaagtgtgt gcgtgtatct tttcctttat tcacatgctc atatttcttt
    29761 gcttgagatt ttagcttaac ctgagcagct tgccaaactt catcggaaac tatagcttca
    29821 tgtatccctt cagatattag atattcatct tgttcaacct gcttatattc atttcttgta
    29881 ccatgaactt tttctaaagt tcttcttcca aatgctattt tcccattata tacaggattc
    29941 tttaatatct ttcttataag acctgcatca aacaaaggat tcttaccatt ctgtcttggg
    30001 atttttctaa ttccatgatt ctctaagtat ttagatatcc cattggctcc tatcgtagta
    30061 tttacatact ggtcgaaaat cgttcttatt gcaactgcct cttcctcatt tataaacagc
    30121 ttgccgtctt caagtttata tccatacgga gcaaagccac cattccattt tccttccctt
    30181 gctttttgaa tgcgatcttc cattgtttga atacggatgt tttctctttc tatttcagcc
    30241 acagctgata aaacagaaat cattagtttc ccagcatctt tagatgaatc aatgccatct
    30301 tcaacgcaga taagattaac tccataatcc tgcattatct gaagtgtaga aagaacatca
    30361 gcggcatttc ttgcaaatct tgataactta aacacaagaa caaaagatac tccatctttt
    30421 ccagatttta tatcttccat cattcgattg aactgtattc taccttcaat agacttgcca
    30481 gacttcccgg catcttcata ctctccaaca atttcataat cattgtaaat agcaaaagct
    30541 ttcattcgtg atttttgtgc ctctaacgaa tacccctcta tctgtattga cgtagatact
    30601 cgtgtataga ggtatacttt tattttttct tttgaca
//
LOCUS       DAVLGK010000026        29517 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLGK010000026 DAVLGK010000000
VERSION     DAVLGK010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.026"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..3698)
                     /locus_tag="VXE01_001258"
     CDS             complement(<1..3698)
                     /locus_tag="VXE01_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0750158.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKETMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALSRMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIAGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKDYQRTKNSQNVVTRIHARSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQAKFSNEGIDKISDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDVFKKAIAYEFDALKEEYISLILDDKAGAGG
                     SRTSGGLSSAAYAILGVTESAQEVALEKALQNADLDFDHKAGLLRQEISDGIELAKAK
                     AEEVKQELSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIVNDIRPKQAQVEAEIAKQVEALVQTKKELAGA
                     STLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAETE
                     IAKQVEALSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELAS
                     RIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDV
                     TFPVALVNDIPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNNVF
                     IRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQRADSLEA
                     GVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQ
                     EILNATKDKASKSELTQTAEELASKIASVQASGRNLFLNSLFKQDIPKTGIWTTSTYT
                     AAIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFY
                     AKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQ
                     EGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRANSLDAGVSRLTEGLRT
                     KADISALNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKAD
                     KTLVVSEAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPENHVTGQKECYRLENNST
                     LTFNLEPDFSSRLYQKVTFSAWIKYENVV"
     gene            complement(3699..4421)
                     /locus_tag="VXE01_001259"
     CDS             complement(3699..4421)
                     /locus_tag="VXE01_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0750159.1"
                     /translation="MTKINELTIDGVKTSSFKCEILVETRPQIIVSSSKTSLLEHDGI
                     SGAIVQSNRHRRLIEKSYHISLINPTDEDLYRFSSLLNREKFWLENEQEPSVKYWCYK
                     VDDFKIIKDDFGAWTVDVKFTCHPTKYFKGSDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSAVETSFTIAGQVIRLEKLSESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            complement(4418..7156)
                     /locus_tag="VXE01_001260"
     CDS             complement(4418..7156)
                     /locus_tag="VXE01_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEV0750160.1"
                     /translation="MAETFEGLYVKFGANTVEFDRSVKGINNALSSLKKDFNNINRQL
                     KMDPDNVDLLNRKLLNLQEQARVGAMKIAELKKQQKELGESEVGSAQWNKLQLEISKV
                     ESQMKVVDQTMNSTKKHIEDVGNPKSILNLNKEINNVAKELDIVNQKLELDPKNVELS
                     EEKMKLLGKQSSLAKDKVQELKRKQEELGKEKIGTEEWRQLQNEIGQAEVEVLKIDKA
                     MGNLGDSSRSATGNIKEATGYLKADVMMNIAEKAGQLGQKMVDAGKKTVDAWSEIDEA
                     MDTVTTKTGLTGEALLGLQEIAKGIATSLPSATFQESADAVGELNTQFGLTGDTLQSA
                     AEYLLKYSKITGEDISNSAINAKKAIDAYGLSNEDLARVLDSVTKVGQDTGQSYDSIF
                     QKAIDGAPQIKMLGLSFKEGATLIGRFEKSGIDSSAALASLSKATVNYAKDGKTLTEG
                     LNETVNAIQNATSKTEAIRIASEVFGNRAAPKMVDAIQRGAFSFNDLAEAAQNSSGTV
                     ATTFAETKDPFDDLTTYSNKAKEGLAEIGGTLLETVIPALEPLMGMLESAVNWFTSLN
                     ETDQQTIVILGLVTTAVMLLLGAIAPLVIAIGAIGAPVGIVVAAIVAAIAAITLIIQA
                     IMNWGTISEWLQSTWDACAAWLSELWTNIVTTATTAWSSFTAWLSEIWSSVVSTGQSL
                     WSSFTSTLSNIFSSLISGAQSLWSSFTSTLSNLWSGLVSTGSNLFNNLSSTISGIFNG
                     ILSTASNIWNSIKSTISNAIDGAKNAVSNAIQAIKNLFNFNISWPHIPLPHFYVSGSA
                     NPLDWLSQGVPSIGIEWYAKGGIMTKPTLFGMNGNRAMVGGEAGAEAILPLNKSTLGA
                     IGQSIANTMNTSNSINVNFSGVTIREEADLNRLADVVGTRIAEELQRKTNLRGGFA"
     gene            complement(7343..7819)
                     /locus_tag="VXE01_001261"
     CDS             complement(7343..7819)
                     /locus_tag="VXE01_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750161.1"
                     /translation="MIKKELSFTAFDSYGEEREYTVTVRFLYSLPAIKMYEQRTGRNF
                     FDDNQKALTAYTQLALATGVNGRLSALTDEEKVKLMPLLMEPDFMNFLTEVIPCLYGE
                     VENGRLVQNELTAETASLAPWFGDLIDIGFFSDLFYEFNRSRAKVPQDRKKPQQKS"
     gene            complement(7821..8489)
                     /locus_tag="VXE01_001262"
     CDS             complement(7821..8489)
                     /locus_tag="VXE01_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0750162.1"
                     /translation="MTYKYDTREVTHGNTTGFFAKISKTESGTLDLKKPYPFTGLRKT
                     SFETSQESNAYYADNVEHVRLQGKKSTEGSITTYQIPKQFMIDHLGKKLTTSTPPALI
                     DTGVNANFIWGYAETVTDEFGSEVEEFHIWTNVKASAPKGSTTTDESSATPKEIEIPC
                     TASPNNFILDSDKKPVSEIVWRDTDKGVVRAKFDKLFASSTPMKLIDFINEALGTTAI
                     VSGG"
     gene            complement(8503..8847)
                     /locus_tag="VXE01_001263"
     CDS             complement(8503..8847)
                     /locus_tag="VXE01_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000534622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV0750163.1"
                     /translation="MGSGSVNVKTLKIDIQNQVLEIIEKAGKSTAGDIRDGSPRRNGV
                     YEKGWTHETIEDIAVVYNNGKEKSLAHLLENGHATKNGGFVAPQEHIRPAYLKNKEIF
                     LNNMKSIKIRPN"
     gene            complement(8834..9181)
                     /locus_tag="VXE01_001264"
     CDS             complement(8834..9181)
                     /locus_tag="VXE01_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750164.1"
                     /translation="MAKKFFTRQEIQEILEKNTLKSKVFYMEREEKSSPDNVILYYRL
                     TPGSSITADDTVHMRKVTIQISHYHKKKLDSIEELMLSNFMCEPSQLNLKQPDTDYLL
                     TTYRIEVFTSGKW"
     gene            complement(9181..9486)
                     /locus_tag="VXE01_001265"
     CDS             complement(9181..9486)
                     /locus_tag="VXE01_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HEV0750165.1"
                     /translation="MKSSRVSIILCYDERTEVEKGVFEKQVVEKKVKAEKEKIYQRRL
                     DKALADGQVLTARFRIRSNYVTDSLDYVKYKGKEYKVNVGTESDDDHYTIIELGELK"
     gene            complement(9483..9818)
                     /locus_tag="VXE01_001266"
     CDS             complement(9483..9818)
                     /locus_tag="VXE01_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000154006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750166.1"
                     /translation="MTILNQIKEMVEVDVEEEIFDTQFLSYINSGISYLTRNNIPINR
                     IDKESELTEWNEIEEDDKETILDWLHLRCVQRFDKSLMTGNSTTRSWIDEELTNILYQ
                     LKAIYGVKS"
     gene            complement(9844..11097)
                     /locus_tag="VXE01_001267"
     CDS             complement(9844..11097)
                     /locus_tag="VXE01_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000855225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEV0750167.1"
                     /translation="MKTLVELMEERQKYADELSEIKLKKASIEEKLKSATIGEEELAQ
                     LKSDAEELVPKAEELKKTISKLDVEIEEKEDNLNKAAKSIKEVQKGKTQMEYLKTKES
                     ALDFARILMDNEGSSNSARKAWEANLVEKGVTDINKILPEPVLIAIQNAFNDYDGILN
                     HVTKDPRYAVRVALQTKQAKAKGHQNGKTKKDESFVFIDYTINSAAVYIKYSFEYADL
                     KKDTTGAYFNYVMNELAQGFIRAVERAVVIGDGKNSDDDDKITEIKSIAEETLDQLFD
                     TQEISVDGEFDSTVLETLVKGIDKLAANTTPILVTSKTIARKLKMVKDGEKRYIDPQP
                     FAPISQTGNVIAGYQVYVYDWMEDATNPIIAFADKAYKMIGDDVSADRFEDYDVTMNR
                     RHIELASVLGGRLGQYKSAVKFTKG"
     gene            complement(11112..11654)
                     /locus_tag="VXE01_001268"
     CDS             complement(11112..11654)
                     /locus_tag="VXE01_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HEV0750168.1"
                     /translation="MEKLKTFVVKSVEEESADFHFEAYASTYGNTDRDGDVMAKGCFD
                     NTLKTKAVVPMCLNHDRNRVIGKHELSVDEKGLRTRSTFNLSDPEAKKTYDLMKMGAL
                     DSLSIGFFINDYESVDAKQPYGGWIFKEVEIFEISVVTVPANPQATIDNIKGFDMSVV
                     DKRIAQANMKQDIMSKLATI"
     gene            complement(11701..12843)
                     /locus_tag="VXE01_001269"
     CDS             complement(11701..12843)
                     /locus_tag="VXE01_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0750169.1"
                     /translation="MNKYINNLREVFARIFRPSNRKSTRTYLQRNLNYWRRNSIYLDN
                     IYNKISTDTAQVRFKHVRITRNPTGVDKMEWFENSDLANVLSFSPNPLEIPVVFWANV
                     TRAMLKDGVAVVVPRWENGRLIEIWLAKKTISWTAERVEIMIDDVEIELPLSDVWVFE
                     NPKLNVTSQLNQITELIDINLDALTEKLGRGNSKLRGFLKLPTKAADEHLKKQAKSRV
                     DSMMELAENGGIAYLEQGEEFMELNKDYSTASKEEMEFLKSQLYHAHGINEKLFTCDY
                     TEEQYRAYYSSVMKLYQRVFSEEINRKYFTKTARTQGNKLLVFFDMADMISFKDLVEG
                     GFKSKYAGLMNSNEFRETYLGLPGYEGGEVFETNLNAVRIEPSESN"
     gene            complement(12852..14564)
                     /locus_tag="VXE01_001270"
     CDS             complement(12852..14564)
                     /locus_tag="VXE01_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEV0750170.1"
                     /translation="MVEMKYFDKYAQLVYSGKIRVCELTMKSIKRVERYKEQYIFKQE
                     EVDKRIEFIEEECSNTKGLAGKLRLALPQKVWLETTWGFYHTVEVTKTDPDTLEEYKD
                     FEERRLIHEVPIIVPRGTGKTTLGSAIGEVGQIIDGEWGADIQLLAYSREQAGYLFNA
                     SRAMLSNEESLLHYMREADILRSTKQGILYETTNSLMSIKTSDYEILDGTNAHYNIFD
                     EVHTYDDDFIKVVNDGSSRKRKNWITWYISTNGTKRDKLFDKYYNIWVDILDEKIVND
                     SVMPWIYQLDDVSEIHNPDMWQKAMPLLGITTEKETIAKDIEMSKNDPAQQAELMAKT
                     FNLPVNNYLAYFSNEECKGWLDKFDKSLFVGNEERSARCVLGVDLSDVNDICSVSFMV
                     VRGEERQYLNKKFMPRHTIEGLPKELRDKYAEWELSGQLHVHELDYNDQAYIFEELRQ
                     FMSENRILPVAVGYDRWNAKELIRLINDYYGDICHDIPQTVKSLSNPLKVYKEKAKMG
                     KIIFDDPVATWNHANVRVKIDANNNVFPNKEKAKEKIDVFASQLDAFICYENFKEDLS
                     YYFD"
     gene            complement(14557..15042)
                     /locus_tag="VXE01_001271"
     CDS             complement(14557..15042)
                     /locus_tag="VXE01_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750171.1"
                     /translation="MILKINEVLEKLGISRATLTRYRKKLGIFEETRSNITKSQFKEL
                     EKLANQRQKYTREERVELSRKTFKLIPKEKMLEINDNDSVGLKNLKTQYNHNQKVIEN
                     FQLEINKVINNGELPDKYLLDGMEKYQKLNMQIMSTIEKQSPQGDSLKEMIQEKLARY
                     G"
     gene            complement(15179..15496)
                     /locus_tag="VXE01_001272"
     CDS             complement(15179..15496)
                     /locus_tag="VXE01_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV0750172.1"
                     /translation="MTFKNPKHSDWFRTWQIKFYNSRHWRTLRNRIRTTKRMRCDMCG
                     RLIHGKSIVDHIIEIDETNYQDESITLNEDNLQLLCLECHNTKTFQSKINLNLENRNI
                     NLF"
     gene            complement(15926..16468)
                     /locus_tag="VXE01_001273"
     CDS             complement(15926..16468)
                     /locus_tag="VXE01_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0750173.1"
                     /translation="MNIVEPLRDKDDIQAMKDYLSSWNEKYYMLFLLGINTGFRVGDI
                     LKLKVKDVQGWHIKVREQKTGKYKSIKMTRPLKNELREFVKDKELHEYLFQSRVGKNK
                     ALSYKTVYWFLKRAAEDLGIDNVGTHTMRKTFGYHYYKKYKNVADLMSLFNHSSPAVT
                     LIYICVRQDELDTKMSNFSL"
     gene            complement(16577..17041)
                     /locus_tag="VXE01_001274"
     CDS             complement(16577..17041)
                     /locus_tag="VXE01_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750174.1"
                     /translation="MGKKNLITARRDYLEFELNDKYLQIDKLIGQRRHELERLYEVKH
                     LTVPGIDDTGASGSGTFVNRSENLAVAYASDPMVLRLENFQTAISKLLDVLEPDDKKI
                     FHLKWGEHTRYDWIQVWHKMENGDTGYLYRHSKQIYRRREIILDTLAKLLFM"
     gene            complement(17185..17472)
                     /locus_tag="VXE01_001275"
     CDS             complement(17185..17472)
                     /locus_tag="VXE01_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750175.1"
                     /translation="MTQTLEEGMKNQSKCIKIPMEIRPFDVGYRIVNKHGQALALKNG
                     ASIFALPSLAEKAIKKEFGKNDPDFDIEKHFVEEVAIVNLSKFHSYFEEVE"
     gene            complement(17472..17972)
                     /locus_tag="VXE01_001276"
     CDS             complement(17472..17972)
                     /locus_tag="VXE01_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0750176.1"
                     /translation="MEEAKMNKQELIDYCNVLKESKSRFINCIDVDRIIDTIKQLDEP
                     EKVKVPRFVAEWIEEARKACKDVVELFEFDFTNDEVRKWFMQERPFDLVARAWLDGYE
                     VEEEKRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEDANFGWVFDCEGI
                     EIEEVE"
     gene            complement(17950..18276)
                     /locus_tag="VXE01_001277"
     CDS             complement(17950..18276)
                     /locus_tag="VXE01_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750177.1"
                     /translation="MMEELKKKVNAVYNWTVEDGKPQPPQQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMAQVVIAVYLIY
                     GGSEDE"
     gene            complement(18248..18457)
                     /locus_tag="VXE01_001278"
     CDS             complement(18248..18457)
                     /locus_tag="VXE01_001278"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750178.1"
                     /translation="MNYDKRTVIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LKKKNKELRRKAEELEDDGRVKEKS"
     gene            complement(18447..18611)
                     /locus_tag="VXE01_001279"
     CDS             complement(18447..18611)
                     /locus_tag="VXE01_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750179.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEL"
     gene            complement(18738..18965)
                     /locus_tag="VXE01_001280"
     CDS             complement(18738..18965)
                     /locus_tag="VXE01_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750180.1"
                     /translation="MLELYFVYNGHCKFYLGTFDNVDDLIEQMEDHQWVFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            complement(18965..19159)
                     /locus_tag="VXE01_001281"
     CDS             complement(18965..19159)
                     /locus_tag="VXE01_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750181.1"
                     /translation="MFILRHGTREDKPFLRSVVIGVTGLDISCSEEKKAMRFVSRGAA
                     VQVGKALRGSFGNFYPVEVE"
     gene            complement(19174..19944)
                     /locus_tag="VXE01_001282"
     CDS             complement(19174..19944)
                     /locus_tag="VXE01_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0750182.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQARVNELADAENERERKYYLEKFSLYDEVLKNATLDNFETPTEKEAEK
                     LVFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLTS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            complement(19938..20096)
                     /locus_tag="VXE01_001283"
     CDS             complement(19938..20096)
                     /locus_tag="VXE01_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750183.1"
                     /translation="MGVLELIEQFEIDYYPLSYEKKTLLADQPIHQVVACLSEMASWH
                     ECGGRLVW"
     gene            complement(20084..20890)
                     /locus_tag="VXE01_001284"
     CDS             complement(20084..20890)
                     /locus_tag="VXE01_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV0750184.1"
                     /translation="MSEIKWIKITTDIFDDEKICLIDALPDPDAILVIWFKILTLAGK
                     HNSNGLLMMTDKVHYTDEMLATIFRRPLNTVRMAIGVFEQFGMIEIIDGIISLPNWEK
                     HQNVDGMEKIKEQTRNRVAKYRKKQKNLALGNVTGNVTVTDGNALEEDKDKNKNRLDK
                     DKNKKRITTTSSGSEENILELFQSEFRRLLSGFEIEEINHLLNENNVDLVKEALKTAI
                     NSGKPNIKYIGGILRNWQMNNVTTVEQVRQSEKKNKDKKEEQEAKDEWGY"
     gene            complement(20883..21179)
                     /locus_tag="VXE01_001285"
     CDS             complement(20883..21179)
                     /locus_tag="VXE01_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750185.1"
                     /translation="MEELIESLDNLIMIAKELEGRESTSRHFITIWENDYKNLLLVKE
                     YLTDYEKLAKDYRDVELKNKLLKIEKMELEGRYIYEDMRMKYRANRRKWGARYV"
     gene            complement(21195..21515)
                     /locus_tag="VXE01_001286"
     CDS             complement(21195..21515)
                     /locus_tag="VXE01_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750186.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIRGYNHAYERGREAERQEIRKNIRRPFKGFTYDNEPPVGLRPEPLALPESKQSA
                     IRLL"
     gene            complement(21601..21858)
                     /locus_tag="VXE01_001287"
     CDS             complement(21601..21858)
                     /locus_tag="VXE01_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0750187.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCE
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            complement(21870..22577)
                     /locus_tag="VXE01_001288"
     CDS             complement(21870..22577)
                     /locus_tag="VXE01_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HEV0750188.1"
                     /translation="MNEIFNFHGQEVRTLTIDDEPWFVGKDVADILGYQNGSRDINRH
                     VDDEDRQNYQNGTFGNRGVTVINESGLYSLILSSKLLQAKEFKRWVTSEVLPAIRKQG
                     GFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAQSLLKKRKARV
                     VACLGGIDSPAYADKIFAQSVFRQAEIDFKDHFDISRYDLLPKKHADAALAYWMTWEP
                     STNTKMKIMKLNSFDEV"
     gene            22631..23056
                     /locus_tag="VXE01_001289"
     CDS             22631..23056
                     /locus_tag="VXE01_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750189.1"
                     /translation="MDYQILIQPAISVILAIISGLWSYIASKANNKAEIEKQAKEHSH
                     IVEKLEKEFHYQIDTLKQQHTLELEKVKQAHELRLQELEKVSQIDTETDKAMKMNDLI
                     YKTFTGEVDLDKALKLADKANNHKQKLNKKFIQKTSKKS"
     gene            complement(23051..23212)
                     /locus_tag="VXE01_001290"
     CDS             complement(23051..23212)
                     /locus_tag="VXE01_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750190.1"
                     /translation="MNEIVWFYFVVIINLIIGFATYYASKRDRKKRINEYKKIQDDEL
                     ERIRNKFNL"
     gene            complement(23223..23420)
                     /locus_tag="VXE01_001291"
     CDS             complement(23223..23420)
                     /locus_tag="VXE01_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750191.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            complement(23437..23640)
                     /locus_tag="VXE01_001292"
     CDS             complement(23437..23640)
                     /locus_tag="VXE01_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0750192.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQAELAKQVSVASSVISELLKYG
                     KGSESVKEKVADVLGIENPWENS"
     gene            complement(23652..23798)
                     /locus_tag="VXE01_001293"
     CDS             complement(23652..23798)
                     /locus_tag="VXE01_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750193.1"
                     /translation="MEDKIIELADYFISENTTYREAKIACEKLFKQASHEIELRALES
                     ETKK"
     gene            23917..24138
                     /locus_tag="VXE01_001294"
     CDS             23917..24138
                     /locus_tag="VXE01_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750194.1"
                     /translation="MSKLTKEDVLQVSQEIINDAIPVIKDMLDEVFKEYPIDMEIRKA
                     ILNSVLVAHKLSTETTVSLLTELVNAQEN"
     gene            24515..24880
                     /locus_tag="VXE01_001295"
     CDS             24515..24880
                     /locus_tag="VXE01_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0750195.1"
                     /translation="MFSLFEKIKELCQNRGISINSLEETLGYSRNTIYSMKNKKPNAE
                     RLQEIADYFNVSTDYLLGRTDNPAIAGDSKEYTWQGKALNVEEMASNVMMFGGRELTD
                     EKKKIIQSIIEGYLKEAGD"
     gene            24893..25276
                     /locus_tag="VXE01_001296"
     CDS             24893..25276
                     /locus_tag="VXE01_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV0750196.1"
                     /translation="MTEKEIISHFQVRIVDFDGELIPDELGFYEKETNTAFLSNKLSK
                     KERVKVLLHELGHKDHTRLEYQNARLRCENEADRNMIHHLVKDAIESLDDPTEFDYLK
                     FMSYYNLKTMTNEVMVKEEYFALME"
     gene            25289..26212
                     /locus_tag="VXE01_001297"
     CDS             25289..26212
                     /locus_tag="VXE01_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HEV0750197.1"
                     /translation="MSYSYVALDVETANDFRGSVCSIGLVKFKDGNIVDAFYTLINPE
                     EEFDDFNIFIHGITPEDVLDSPTFPEVRKAIVDFIGSDIVVAHFAQFDMGALKDVYQK
                     YELDFDNIEYICSYRLAKVALPGQLNYKLKRLAKNLNIELDHHNALSDARASGLILEY
                     LLSTNSFSDLNAFLKEYSYNKTGLLGQYGFKRKKSYQYKENLIYQPTEEEKAAMNPDH
                     YFYGLYFCFTGKLERMTRKEANKTTALVGGIPEKGVTKHTNILVVGEQDWRVVGTDGL
                     SSKMKKAQTLLEKGQDIEIMTENDFIRLLEE"
     gene            26401..27549
                     /locus_tag="VXE01_001298"
     CDS             26401..27549
                     /locus_tag="VXE01_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0750198.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(27791..29077)
                     /locus_tag="VXE01_001299"
     CDS             complement(27791..29077)
                     /locus_tag="VXE01_001299"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV0750199.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(29308..>29517)
                     /locus_tag="VXE01_001300"
     CDS             complement(29308..>29517)
                     /locus_tag="VXE01_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV0750200.1"
                     /translation="TNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDF
                     IVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT         8482 a         6456 c         4900 g         9679 t
ORIGIN      
        1 actacatttt cgtacttgat ccaagcgcta aaagtaactt tttggtacaa ccttgagctg
       61 aaatctggtt caaggttgaa cgttaaagta gagttgttct ctagcctata gcattctttt
      121 tgacctgtga cgtggttttc aggtaatttt tcaattacag ctccaaccgt cttggatttt
      181 atccatagat tccggcctcc caccttcatt tttgaaaatt cttcacgcaa tttcccggct
      241 tcagatacaa ctaaagtctt atctgcttta tccttggttg cgttcaagat ttcctgacgg
      301 atagagccgg ctcgcacctc aaattcagcc tgactcaact tctgatttag cttgttctgc
      361 gtgtctgtct caagactctt caccgattgc cggatatttt cagcagtcac attgagtgcg
      421 ctgatatcgg ctttggttct aaggccttca gtcagacggc ttacaccagc gtcgagtgag
      481 ttggctcgtt gtttgaaggt cgattctact gttgaaatct gaccttctat atcttcagga
      541 gcttctgaat aagaagtatc tacatcgctt atttcaaact tcggcatcca aatccaaacg
      601 gttccttcct ggttgaaatt gaacaaccat tcatttgtgg tctgcttaga ttcgtttgtc
      661 caaccttttg gaatatggac aacatatcgt ttaatttctg tcgacaatgt cacatttcca
      721 gttttatatc cgatattccc taatcgagat cttagcatta ttccattttt atttgcctta
      781 gcataaaaac taatggttac atcttgatta gtcgtacttc cgggaattac tttcccgaat
      841 tgacccagag ctggataagt aaccttggga ttacctccat cacggccaga tggattcaga
      901 cctataattt taagagcctt gtgtccaaga tacttacttt cgctatcgat agcagccgta
      961 tatgtactcg ttgtccaaat tcctgttttt ggaatatcct gcttgaatag tgagttcaag
     1021 aatagatttc gaccggatgc ctgcacactc gctatcttac tagccagctc ctcagctgtc
     1081 tgcgtgagtt ctgacttgct ggctttatcc ttggttgcgt tcaggatttc ctgacggata
     1141 gagccagctc gcacctcaaa ttcagcctga ctcaacttct gatttagctt gttctgcgtg
     1201 tctgtctcaa gactcttcac agattgccgg atattttcag cagtcacatt gagtgagctg
     1261 atatcggctt tggttctaag gccttcagtc agacggctta caccagcttc gagtgaatca
     1321 gcacgctgtt taaagttgga ttcgactact gagacacggt cttcttggtc ttcatacgct
     1381 ggttgatagg ctggaaaata attaccaacc gataacatag cgttctcaat gacgacctgc
     1441 agaccagcag gaaatccata attagtacca aaacgaatga acacattatt agtctgatag
     1501 tcctcagaag aactagacaa gtcaatcgta aactcaaaat gttggcgttc gacagttcca
     1561 cctttaaaaa ttaagtttct gtaggcatac catggatgag cactaaaatg caccatagca
     1621 ggtatgtcat ttactagggc gacagggaaa gtcacatcaa aagatatgcg aacataatca
     1681 cgcttgaacc tgtcactgtt cttccagaaa tcaggaacta tgaatgttcg atagtcgtat
     1741 accgcttgac ctcctgttgt gaacgttctt gaacgtgaat tcctgaagta attccgtgaa
     1801 ctacctgcct gcacactcgc aatccgacta gccagctcct cagctgtttg cgtgagttct
     1861 gacttgctgg ctttaccatt ggccaagttg gtcagttctg acagtctacg agtcgtcgtc
     1921 tcctcatacg tcgcttgcgc tgacttcacg ccagccagtt catttttagt ccggctaagt
     1981 gcttcaactt gcttggcaat ctcagtttca gcctgtgctt gcttcggtcg aatatcattc
     2041 gcgatagtcc gtttcagagc gtccaagtca cccgacagag ccgtttgtgc gctcgtagtc
     2101 tgcgacttaa acgcttcaag tctagcaaca gaatccagct caatccgctt agcttcctgt
     2161 gcaagcaggg tacttgcgcc agccagttct tttttggtct gaacaagtgc ttcaacttgc
     2221 ttggcaatct cagcttcaac ctgtgcttgc ttcggtcgaa tatcattcac gatagtccgt
     2281 ttcagagcgt ccaagtcacc tgacagagcc gtttgtgcgc tcgtagtctg cgacttaaac
     2341 gcttcaagtc tagcaacaga atccagccca atccgcttgg attcctgagc aagagaacta
     2401 cttgcgccag catttcgcaa agcttcctca gccttgcgct tagcttcttt caatggcccg
     2461 ttgtcaaagc tattaaagcg ctgattgata gtgtcagaca gttcttgctt gacttcttcc
     2521 gccttggcct tggcaagttc gatgccgtca gaaatttcct gtctaagcaa tccagcctta
     2581 tgatcaaagt ctaagtcagc attttgaaga gccttttcaa gggcaacttc ttgtgcagat
     2641 tctgttactc caagaatggc atacgctgcg ctagataagc caccagatgt tctagaacca
     2701 ccagctcctg ccttatcatc gagaatcaga gagatatatt cttcttttaa ggcatcgaac
     2761 tcataagcaa tagctttctt aaatacatca acattatgtt tccagctctt gagattgacc
     2821 gtatcaccca tgtgaacaac ttgcccatca agttcataag cttcaatctt gatagcgtca
     2881 gagatcttgt caatgccctc atttgagaac ttagcctgtg cccacttctg caactcttca
     2941 acagattttg cgttgttgtt ctcatactct ttttcgttta tgtaaggata agaattaata
     3001 agaggactat caacagtcac tctgatagtt gtttcctttt cagcaccttc aggcttaaat
     3061 gtggatcgag catgaatcct tgtaacaaca ttttgactgt ttttggttcg ttggtagtcc
     3121 ttcagattct tatgtgttgt aataacaaca ccacgattct ccccacgact cttcttgaca
     3181 gtcatcgcaa agttatcacg caccagctcg ccttcccacg ttccggcgat actatgcttg
     3241 ccgtccagca atacagagta cagggtttct gtctcagtcg tgttgaatgt cctacggtcc
     3301 tggatatcac tgttgaatga gaagtctcca agagccgttt tggtgttttg taccatgcga
     3361 gaaagagcca tgccacaact ctgactagtc acactcattt gtgtgataga tcgttgcatc
     3421 acatcatctg aaatgtgata ggctgtgatt tccagatggt cattgtgctc aacaggtttc
     3481 ttgatacgaa atagctgcgc tcctaagaca ggagtcggag cctttatcag catatcttct
     3541 tggatgagct ggtaaatacc agaatcagaa ataggatatt tcacagtcaa ggtaaaatcg
     3601 ccattcatag tttctttcac aatcgccgaa gtcgcttcat gaagtggctc cccgttccat
     3661 cgaacggttc ttacatcttt attaagtaga taaagcaatt atgcccaccc ccaaaccgtt
     3721 tcgatttcaa tcgattgaat acctgggcct aaaacaaccc caatattctt aactttcgct
     3781 ggatcaactg tgataaaatc ccctgaccat ttcactggct tccctgttgt cgttttaaag
     3841 ctaggattgt caggattatt aaccatcaca agcgattctg agagtttttc aagcctaatg
     3901 acctgaccag cgattgtaaa tgaagtctca acagcgctct gaccaacgat tgtgatttta
     3961 ggaaaagcaa gagcagaacc ttgaacggtc aaggttccac ttcttgtcaa tctctgtgta
     4021 tcggagcctt taaagtattt tgtaggatgg caagtgaatt ttacatccac cgtccatgca
     4081 ccaaaatcat ctttaataat tttgaaatca tccactttat agcaccaata tttcacgctt
     4141 ggctcttgtt cattctctaa ccaaaatttt tcacgattta acagagaaga aaaacggtat
     4201 aagtcttcat ccgttgggtt aatcaagcta atgtggtagc ttttttcaat caacctacga
     4261 tgcctatttg attgaacaat tgcaccacta atcccatcat gttctaaaag actagttttt
     4321 gaggaggata cgatgatttg tggtcgtgtt tcaaccagaa tctcacattt aaatgatgat
     4381 gttttcactc catcaatggt taactcatta atttttgtca tgcgaaacct cctctcaaat
     4441 tagtttttct ttgtagttct tcagcaatac gtgttccgac tacgtcagct agtctattca
     4501 aatccgcttc ttctcggatg gtcactcctg agaagttgac attgatgcta ttcgatgtat
     4561 tcatcgtatt agcaatgctt tgtccaattg caccaagagt tgacttattg agtggaagga
     4621 ttgcttctgc accagcttct ccaccaacca ttgctctatt tccattcatt ccaaataaag
     4681 ttggtttggt catgatacca cccttcgcat accactcaat accgatgctt ggaacgccct
     4741 gacttaacca gtctaatgga ttggctgaac cacttacata gaagtgtggt aatggaatgt
     4801 gcggccaact gatattgaaa ttaaatagat tcttaatagc ttggatagcg ttagatactg
     4861 catttttagc accatcaata gcatttgaaa tagttgattt gatagagttc caaatattgc
     4921 tagcagtgga taagatacca ttaaaaattc ctgaaatcgt gctactcaaa ttattaaaca
     4981 aatttgaccc ggttgagacc aggccagacc ataaattgga aagggtagaa gtaaaacttg
     5041 accacagtga ctgagctcct gaaatcaaac ttgagaaaat attggacaag gtgctagtaa
     5101 agctagacca caaagactgt cccgttgaga ctactgaaga ccaaatttca gaaagccaag
     5161 cagtgaaact tgaccacgct gtagtagcag tcgtaacaat attagtccac aattcagaaa
     5221 gccaagcggc gcaagcatcc cacgtcgact gaagccattc agatatggtc ccccagttca
     5281 tgatggcctg aatgatgagt gtaatagcgg caatagcagc aactattgcc gctacgacaa
     5341 ttccgacagg cgcacctatt gcacctatag caatgactag cggtgctatt gcaccaagca
     5401 gtagcattac agcagttgta acgaggccaa gaatcacgat agtctgttga tcagtttcat
     5461 ttaagctggt aaaccaattg acagcagatt caagcatgcc catcaaaggt tctaaagctg
     5521 gtataacagt ctcaagtagt gtaccaccta tctcggcaag cccttctttt gctttgttgg
     5581 aataggttgt taggtcatca aatggatctt ttgtctcagc aaatgttgtt gctacagttc
     5641 ctgatgagtt ttgtgctgct tcagctaaat cattaaaact aaatgcccca cgttggatag
     5701 catctaccat tttaggagcg gctctatttc cgaaaacttc agaagcaatt cttattgctt
     5761 ctgtcttact agtagcattc tgaattgcat tgacagtctc gttcaacccc tcagtcaatg
     5821 tctttccgtc tttagcatag tttactgtag cctttgaaag tgaagctaaa gctgcagaag
     5881 agtcaatccc acttttttca aatctaccaa ttaatgtcgc cccctcttta aaagataatc
     5941 ctagcatctt aatctgtgga gctccatcaa ttgctttttg aaagatggag tcataagatt
     6001 gaccagtatc ctggccgacc tttgttactg agtccaatac tctcgctaga tcctcattag
     6061 ataaaccgta agcatcaatt gctttcttgg catttattgc ggaatttgaa atatcttctc
     6121 cagttatttt cgaatatttc aataggtact ctgctgcaga ttgcaaagta tcaccagtaa
     6181 gtccaaattg tgtatttaac tcaccaactg cgtcagcaga ttcttgaaat gtagccgatg
     6241 gtaaggatgt agcgattcct tttgcaattt cctgaagtcc taacaaggct tcgccagtaa
     6301 gtccagtctt cgtcgtaaca gtatccatcg cttcgtcgat ttcagaccat gcatctactg
     6361 tttttttacc agcatcaacc attttttgac ctagttgtcc tgccttttca gcaatgttca
     6421 tcattacatc ggcttttaag tatcctgtag cttccttgat gtttcctgtt gctgaacggc
     6481 tcgaatcccc taaattcccc atggctttat ctatctttaa cacctcgact tctgcttgcc
     6541 caatttcatt ttgaagttgt cgccattcct ctgttccgat tttttccttt cctaattcct
     6601 cttgtttccg tttcaactcc tggaccttat ccttggctaa tgaagattgt ttacctaata
     6661 acttcatttt ttcttcggac aactctacat ttttaggatc taattcaagc ttctggttga
     6721 cgatatcaag ttcttttgca acattgttga tttctttgtt gagatttaaa atagactttg
     6781 gatttcctac atcttcgata tgttttttgg ttgaattcat tgtctggtca acaaccttca
     6841 tctgtgattc aactttagaa atttcaagtt gaagcttatt ccactgtgct gacccaactt
     6901 cagattctcc cagttccttt tgttgctttt tgagttcagc aattttcata gcaccaacac
     6961 gagcttgttc ttgtaagttg agcaacttac gattcagcaa gtcgacattg tctggatcca
     7021 tcttcaattg tctattgatg ttgttgaaat cttttttcag actagataaa gcattattga
     7081 taccttttac agatctgtca aattcaacag tattagcacc aaatttgaca tataagcctt
     7141 caaatgtttc agccatagat ttcctccttt cagttttagt cagacattac atttagtaat
     7201 tctgcgtttg ataaagtttt cttctcattt tcattgatac tcatctgatg tagtgttccc
     7261 atcagataat taaagtgttg actttctgcc caaaaaacat ccatccgatt ttcaaaaaca
     7321 accttataaa ttttttcaga agttatgact tctgttgagg cttttttcta tcttgaggaa
     7381 cctttgctct acttcggtta aattcataaa agaggtctga aaaaaaacca atatcaatca
     7441 aatcaccaaa ccaaggagca agagaggctg tttcagcagt cagctcattc tgtaccaagc
     7501 gaccattctc aacctcaccg tacagacaag ggatgacttc agttaggaag ttcatgaaat
     7561 ctggctccat aagtaatggc attagtttga ccttttcttc atcagttaaa gcagataaac
     7621 gaccatttac accagttgca agagcaagct gtgtgtaagc tgtgagtgct ttttggttgt
     7681 catcaaagaa gttgcgacct gtccgctgtt catacatctt gatagctggt aaagagtaaa
     7741 gaaagcgcac tgttacagtg tactctcttt cttcaccata actatcaaac gctgtgaatg
     7801 atagttcttt tttaatcatt ttatcctcct gacacgatgg ctgttgttcc taaagcttca
     7861 ttgataaaat caatcaattt cattggggta cttgaagcga acaatttatc aaatttagca
     7921 cggacaacac ccttgtctgt atcacgccat acaatttctg aaacaggttt tttatctgaa
     7981 tctagaataa aattgttggg tgacgcagta catggaattt caatttcttt tggtgtagca
     8041 gagctttcat ctgttgtagt gctgcctttt ggagctgatg cttttacatt ggtccagatg
     8101 tggaactctt caacctcaga accaaactcg tctgtaaccg tttcagcata tccccaaata
     8161 aaattcgcat tcacaccagt atcgatgagc gctggaggag ttgaagttgt cagcttttta
     8221 cccaagtgat caatcatgaa ttgtttagga atttgataag tcgtgatgga tccctcagtt
     8281 gatttcttac cttgaagacg gacgtgctcc acgttatctg cgtagtatgc atttgattct
     8341 tgtgaagttt caaaagatgt ttttcgcaat cctgtaaatg gatacggttt ttttaaatcg
     8401 agtgtgccag attctgtttt ggaaatcttg gcaaagaatc ccgtggtatt accatgagtt
     8461 acctctcgtg tgtcatattt ataagtcatt gtgactcctt ccttaatttg gtctgatttt
     8521 tattgatttc atattattga gaaagatttc tttatttttg aggtatgctg gtctgatgtg
     8581 ttcttgaggt gctacaaatc caccattttt tgttgcatgg ccattttcta acaagtgagc
     8641 aagcgacttc tctttcccat tgttatatac tacagcgata tcttcaatgg tctcgtgagt
     8701 ccatcctttt tcatatactc cgtttcttct aggacttccg tctctaatgt ctccagcggt
     8761 gctttttcct gctttttcta tgatttctaa aacttgattc tggatatcga tttttaatgt
     8821 tttcacatta acgctaccac ttcccacttg tgaatacctc gattctgtag gttgtaagta
     8881 agtaatctgt atcaggctgt tttagattca actgactagg ttcacacata aaattagaca
     8941 acatcaattc ctcaatgctg tctaatttct tcttgtgata gtgactgatt tgaatagtca
     9001 cttttctcat gtgtactgtg tcatcagcag taatactact acccggagtt aaacgatagt
     9061 aaagaataac gttgtcagga gaggactttt cctcacgttc catatagaac acttttgatt
     9121 ttaaagtgtt tttttctagg atttcttgaa tttcttgcct ggtgaagaac ttcttagcca
     9181 ttatttcaat tctcctaatt caattatcgt gtagtggtca tcatcagatt cagttccaac
     9241 atttaccttg tactctttcc ctttgtactt cacgtagtct aaggaatctg tcacatagtt
     9301 agaacgtatc cgaaatcttg ctgtcaaaac ttgaccatct gccaaagctt tatcaagtct
     9361 acgttggtag atcttctctt tttcagcttt gactttcttt tctacaactt gtttttcaaa
     9421 aacacctttt tcgacctctg tacgctcatc gtaacaaagt atgattgata ctctagatga
     9481 tttcatgatt taactccgta aatagctttt aattgataaa gaatatttgt caattcttca
     9541 tcaatccagc tccttgttgt tgaatttcct gtcatcaagg atttatcaaa tctctgaaca
     9601 catctcaaat gtaaccaatc taaaattgtt tctttatcat cctcttcaat ctcattccat
     9661 tctgtcaatt cgctttcttt atcgatgcga ttgataggaa tgttgtttct cgttagatat
     9721 gaaatcccac tatttatgta gcttaaaaat tgagtgtcaa agatttcttc ttcgacatca
     9781 acttcaacca tttctttaat ttggttaagg attgtcattt tagactcccc tttctattta
     9841 aaatcaacct tttgtgaatt tcacagctga tttgtactga ccaagtcggc caccaagcac
     9901 gctagcaagt tcgatatgac ggcgattcat cgttacatca taatcttcaa agcgatcagc
     9961 agaaacatca tcaccaatca tcttataagc cttgtcagca aatgcgataa ttgggttagt
    10021 cgcatcttcc atccagtcat agacatatac ttggtaacca gcaatgacat ttcctgtttg
    10081 tgaaattggt gcgaatggtt gtggatcaat gtagcgtttt tcgccatcct taaccatttt
    10141 aagtttacgg gcaatggttt ttgaagttac caaaattgga gttgtatttg cagcaagttt
    10201 atcaatccct ttgacgaggg tttctaaaac agtactgtca aattccccgt caacactgat
    10261 ttcttgtgta tcaaatagtt gatcaagtgt ttcttctgca atagatttaa tttcagtgat
    10321 tttgtcatca tcatcactat ttttaccatc gccgataaca acagcacgtt caactgcacg
    10381 gataaagcct tgtgctaatt cattcatcac atagttgaag taagcacctg ttgtatcctt
    10441 cttcaagtca gcatactcaa aactgtactt gatgtagaca gctgcagagt tgattgtata
    10501 atcgataaat acaaaagatt catctttctt tgttttgcca ttctgatggc ctttagcttt
    10561 tgcttgtttc gtttgaagtg caacacgtac tgcataacga ggatctttgg ttacatggtt
    10621 caggataccg tcgtaatcat taaatgcatt ttggattgca atcaatactg gttcaggtaa
    10681 gattttgtta atatcagtta cacctttttc aaccagattt gcttcccacg ctttacgggc
    10741 actgtttgag cttccttcgt tatccatgag aattcgagcg aaatcaagtg cagattcttt
    10801 ggtttttaag tattccattt gtgtcttacc tttctgtact tccttgatag atttagcagc
    10861 tttgttgaga ttatcctctt tttcttcaat ctcaacatct aacttagaaa ttgttttctt
    10921 gagttcctct gctttgggta ccaattcttc tgcatccgat ttcaactgtg caagttcttc
    10981 ttctccaata gttgctgact tcaatttctc ttcgattgaa gcttttttta atttgatctc
    11041 agataactca tctgcatatt tttgtcgttc ttccatcaat tcgactagtg ttttcatttt
    11101 ttgctccttt tttaaattgt tgcaagttta ctcatgatat cttgcttcat gttcgcctga
    11161 gcgattcgct tgtcaaccac agacatatca aatcccttaa tattatcaat ggttgcttga
    11221 ggattggctg gcacggtcac gacagatatt tcaaagattt caacttcttt aaaaatccat
    11281 ccaccgtaag gttgcttagc gtcaactgac tcataatcat taataaaaaa tccaatgctc
    11341 agactatcca gtgcccccat cttcatgagg tcataggttt tcttagcttc tggatcgctt
    11401 agattgaatg ttgaccgtgt tcgcagacct ttttcatcta ccgacagctc atgcttaccg
    11461 atgacacgat tgcgatcgtg atttaagcac atagggacga cggccttagt tttcagggta
    11521 ttgtcaaaac accccttggc catcacatcg ccatctctgt cggtattgcc ataggtggag
    11581 gcataagcct caaagtgaaa gtcagctgac tcttcctcaa ctgacttgac gacaaaggtt
    11641 tttaactttt ccatagccta cctcctttct taaaatttct gccaaccgcc caccctattt
    11701 ttaattactt tcgctcggct cgatacggac tgcatttaga ttggtttcga atacttctcc
    11761 accttcatat cctggaagcc ctagataggt ttcacggaat tcatttgaat tcatcaaacc
    11821 tgcgtattta gatttaaatc caccttctac tagatccttg aatgaaatca tgtcagccat
    11881 atcaaagaag accaagagct tgtttccttg tgtccttgcc gtcttcgtga aatattttct
    11941 attaatttct tcagagaata cacgttgata taatttcatg acgctagaat agtaagctct
    12001 atattgttct tctgtgtagt cacaagtaaa caatttttca ttaatcccat gagcatgata
    12061 aagttgagat ttcagaaact ccatttcttc tttagaagcg gttgagtaat ctttgtttaa
    12121 ttccataaac tcttcacctt gctcgagata ggcaatgcca ccattttcag caagttccat
    12181 catgctatca actcgactct tagcttgttt cttcaaatgt tcatctgctg ctttagttgg
    12241 tagttttaag aatcctctca actttgaatt ccctctgcct aacttctcgg ttaacgcatc
    12301 aaggttgata tcaattaatt ctgtgatttg gtttagttga cttgtcacgt ttaatttagg
    12361 attctcaaaa acccagacat cgctaagagg tagctcaatc tctacatcat caatcatgat
    12421 ttcaactctc tctgcagtcc atgatattgt tttctttgca agccaaattt caatcagtcg
    12481 accattttcc caacgtggaa caacgactgc aacaccatct ttcagcatag ctcttgttac
    12541 atttgcccaa aatacaactg gtatttcaag aggatttgga gagaaagata aaacatttgc
    12601 aagatcacta ttttcaaacc actccatctt atcaactcct gtcggatttc gagtgattct
    12661 cacatgctta aatcgaactt gtgcagtatc tgttgaaatc ttattgtaga tattatctaa
    12721 gtaaatcgaa tttcttctcc aataattcaa atttctttgt aaataggtcc ttgtggattt
    12781 tctattactt ggtctgaaaa tcctagcaaa gacctctctt agattattta tatatttgtt
    12841 cattcttcac ctcaatcaaa ataataactc aagtcttcct tgaaattttc gtagcaaata
    12901 aaagcatcta actgactagc aaatacgtca atcttttctt ttgccttttc tttatttgga
    12961 aatacattgt tattcgcatc gattttaaca cgaacatttg catggttcca agttgccaca
    13021 ggatcgtcaa agatgatttt ccccatctta gctttttctt tatacacttt taaaggattg
    13081 gataagctct tgaccgtttg tggaatgtcg tgacatatat ctccatagta gtcattaatt
    13141 aatcgaataa gctcttttgc attccagcgg tcatatccga ctgcaactgg taagattcta
    13201 ttctcgctca taaactgcct taactcttca aaaatatagg cttggtcatt gtagtccaac
    13261 tcatgaacat gaagctgtcc actaagctcc cactcagcgt atttgtccct tagttctttt
    13321 ggaagtcctt caatcgtatg acgtggcatg aatttcttgt tcaaatactg acgctcttcg
    13381 ccacgcacca ccataaatga gaccgaacaa atgtcattga catccgacaa gtcaacacca
    13441 agtacacagc gagcactccg ttcctcattt ccgacaaaca aactcttatc aaacttatct
    13501 aaccaaccct tacactcttc attactgaag taagcaagat agttattaac agggagatta
    13561 aatgttttag ccatcagctc agcctgttgt gctggatcat tcttgctcat ttcaatatcc
    13621 ttggcaatcg tctccttctc agtcgttata ccaagtaaag gcatagcttt ctgccacata
    13681 tctggattgt gaatttcaga aacatcatcc agctgataaa tccaaggcat gaccgaatca
    13741 ttgacaatct tttcatcaag aatatctacc cagatgttgt aatatttatc aaaaagcttg
    13801 tcccgtttcg ttccattggt ggagatatac caggttatcc aattttttcg cttacgactc
    13861 gaaccatcat tcacaacctt gatgaagtca tcatcataag tgtgcacttc atcaaaaata
    13921 ttgtagtgag cattagtacc atcaaggatt tcatagtcgg aagtcttgat tgacataaga
    13981 ctattagttg tctcgtacaa gataccttgt ttagttgacc gtagtatgtc agcctcacgc
    14041 atatagtgta gtaagctctc ttcgttcgac agcatagctc tagaagcatt aaacagatag
    14101 ccagcttgtt cacgactgta agctagaagc tgaatatcag caccccactc accgtcaata
    14161 atctgaccaa cctcaccaat ggcagaacca agggtggttt ttcctgtacc acgaggtaca
    14221 ataataggca cctcatgaat gagacgcctt tcttcaaaat ctttatattc ttcaagtgta
    14281 tcgggatctg tttttgtaac ttcaactgta tgataaaaac cccacgttgt ttctagccaa
    14341 accttctgag gtaaagccaa acgtaacttg ccagcaagac ctttagtgtt gctgcactct
    14401 tcctcaatga actcaatccg tttgtcaact tcttcttgtt taaagatgta ttgttccttg
    14461 tacctctcta cacgtttaat cgatttcatc gtaagttcac aaacacgaat cttacctgag
    14521 tagaccagct gagcatattt atcaaaatat ttcatctcaa ccatatcgag ccaacttctc
    14581 ctgaatcatt tctttgagac tatcaccctg tggactctgc ttttcaatcg ttgacataat
    14641 ctgcatgttt agcttttgat acttttccat tccatcaagt agatacttat caggtagctc
    14701 accgttattg atgactttat tgatttctag ctggaagttt tcaatcactt tttgattatg
    14761 attgtattga gtttttaaat ttttcaaacc tactgaatca ttatcattga tttcaagcat
    14821 tttttctttt ggaatcaact tgaaagtctt acgagataat tcaacgcgtt cttctcttgt
    14881 atacttttgc cgttgatttg ccagcttttc taactctttg aactgacttt ttgtgatatt
    14941 tgaccgagtt tcttcaaata tgcctagctt ttttcgatac ctggtgaggg tagcacgact
    15001 tattcctagc ttttctaaaa cttcattgat tttcaaaatc atgctccttt cttgtatcaa
    15061 ttttcgttat ttttggggga gaggtatata agaggattga caccgttatt attttgggtg
    15121 tgtgaaaatt ttaaataggg gggatctgac aaaaataaaa aattcaaaaa ataaaaaatc
    15181 aaaataaatt aatattccga ttttctaaat ttaaatttat tttactttga aatgtttttg
    15241 tattatgaca ctcgagacaa agtaattgca gattatcttc gttgagagta atagactcat
    15301 cttgataatt agtttcatca atctctataa tatggtcaac aatgctcttg ccatgaatta
    15361 agcgtccaca catatcgcag cgcatacgct ttgtagttct gattctattt ctcagagttc
    15421 tccaatgtct cgagttgtag aatttaatct gccaagttct aaaccagtca gagtgtttag
    15481 gattcttgaa tgtcatagct tgaatgattc aactcggatt tttcttgtgt atctgttcat
    15541 gaacgaaatc atcttataca ttggcttgtc ccatgcataa attattgatg tgtcaactag
    15601 aatctcacta gtcaacgaat acggatacct ttttggtctc atgcttacct ccaacaaaaa
    15661 gagaacatat ctagacttgc tctccgaatt tttcgcatga tacaaatata tcagatccat
    15721 tttgtcaatt ctatatcttt ttttgacaag atttattttt gagttttgaa tttatgtaaa
    15781 atatctctgt tgaattagtt atatcttata ttttatccaa ttttgtttca tactaaaaaa
    15841 ctagcacgga caacgcttca ggccctcttc aaaatataaa ctagaaacct cctcgttatg
    15901 gatagttgaa aaaatcaaaa aaatattaga ggctaaaatt actcatctta gtatcaagtt
    15961 catcttgcct tacacaaata taaattagtg taactgctgg acttgaatga ttgaataatg
    16021 acatcaagtc tgcaacgttc ttgtacttct tgtagtaatg atagccaaat gtttttcgca
    16081 tcgtgtgagt tccgacatta tcgattccta agtcttcagc agctctttta agaaaccagt
    16141 ataccgtctt atagctgagc gccttattct ttccgacacg actctgaaat agatactcat
    16201 gtaattcttt atctttgaca aattccctca attcattctt gagtggcctt gtcattttaa
    16261 tgctcttgta tttccctgtt ttctgttccc taactttaat atgccaacct tgaacatctt
    16321 taacctttag tttgagaata tctccgacac gaaaacctgt attgattccc aaaagaaata
    16381 acatgtaata cttttcattc caagatgata gatagtcctt catggcttgg atatcatcct
    16441 tatctcgtaa cggttcaaca atattcatag ttttactcct ttcacaaaaa aataaagcac
    16501 taagattttc tcagtgcttt gtatagtatc aatctatcat attctttttg tcaatgctat
    16561 actttttttt gacaagttac atgaacaata actttgcaag tgtatcaaga atgatttcac
    16621 gtcttctgta aatctgctta ctgtgcctgt atagataccc agtgtcacca ttctccattt
    16681 tatgccaaac ttgaatccaa tcgtacctag tgtgttctcc ccatttcaaa tgaaagattt
    16741 ttttatcatc aggttcaagt acatcgagta gctttgaaat tgctgtttga aagttttcca
    16801 gtcttaaaac catcggatcg cttgcataag caactgctag gttctcagac ctatttacga
    16861 acgtgccact tccgcttgca ccagtatcat caataccagg aacagtgaga tgtttcactt
    16921 cgtacaatcg ttctaattca tgtcttcttt gaccaatcaa tttgtcaatc tgtaagtatt
    16981 tatcattgag ttcaaactcg agataatctc ttcgtgctgt tattaggttc tttttgccca
    17041 aaccttacct cccatatatc ttttagtttt gacccagtag aactacccct gtttttgaat
    17101 cgtcttttag caaatccaat acaatttcta aaacttgctt acctaaaatc aattgtgtct
    17161 ctaaaatatt ttgctcatct tccatcactc cacctcctca aaataactat gaaatttact
    17221 taaattgaca atagcgacct cttcaacaaa atgtttttca atgtcaaagt ctggatcatt
    17281 ttttccaaac tctttcttta tcgctttttc ggccagcgaa ggtaaagcga atatacttgc
    17341 tccgtttttt aaggcaagcg cttgaccgtg tttatttact attcgataac ccacatcaaa
    17401 cggtctgatt tccattggga tttttatgca tttactttga ttcttcattc cttcttcaag
    17461 tgtttgtgtc atcactccac ctcctcaatc tcaattcctt cacaatcaaa cacccagccg
    17521 aagtttgcgt cttctagttc tttttgagta cctttataat tcctagctgt tatatcttga
    17581 ctaaaataaa gagtactccc tgattgcgat ttgaccaaag gctgcctatt ttttaaagtc
    17641 accaaatacc gcttctcttc ctcgacctcg tagccatcaa gccatgctct agctactaaa
    17701 tcaaatggtc tttcttgcat aaaccatttt ctaacttcat cgttcgtgaa atcaaattcg
    17761 aataattcta ccacgtcttt acaagctttt ctagcttcct caatccattc agccacaaac
    17821 cgcggaactt tgactttttc tggttcgtct agttgtttga ttgtatctat gattctgtct
    17881 acatcaatac aattgataaa tctactttta ctttctttta aaacgttaca ataatcaatc
    17941 aattcctgct tattcatctt cgcttcctcc ataaatcaaa taaactgcaa taactacctg
    18001 agccatgctt ggcgaatagc caacccaatc atcaaactcc ttagattttg gcaaccaacc
    18061 cttagtagct cccaaatcat agtctgtagg cttttcatca gcgaagatgc attccatcgc
    18121 tcccataaac gtcataccat cttctgccat ttcccaaaaa tagtccgccc ggtctttcac
    18181 tgcttgtggt aaatcttgct ggggaggttg cggcttcccg tcttctaccg tccagttgta
    18241 tactgcatta acttttttct ttaactcttc catcatcttc caactcctcc gctttccgtc
    18301 ttaattcttt attctttttc ttcaacaaat cgcgctccag cgctctaatc cgtctcttgc
    18361 gtgcatcaca cggcttcgaa tactcgatta tcttctcttc gttttgctcg attgtgcgtt
    18421 tcagtccatc aatgactgtt cgtttatcat aattcatctt ctaaaaatct ttcaatagct
    18481 tctctgtagg agacttccac cagaccgtct aagtcgttca gggcttcaat atagtctgga
    18541 cgcccttgtc catactgctc tttcaaaaat tcaacaaaga gatgaatttc ctgataggtt
    18601 actccaacca tatttcttac ctcccactaa aaatgtaacg ttattgatca tctttctttt
    18661 cctttcttgc tgcacgttcc ccgactaaat agccgagaaa taaccacaga atagccattc
    18721 caaattcttt aataagttca atcatttttt tctcctcctg aaaaagtcgc taaatagtaa
    18781 caatccttcg aaccgtagtc aaaccgtgtc gtccgctgac caatgtgctt ctgaaatctt
    18841 ggatgagtga tagccgagaa aacccactga tgatcttcca tctgttcaat gagatcatcg
    18901 acattgtcaa acgttccaag gtaaaacttg cagtgcccgt tgtagacgaa gtaaagctct
    18961 aacatcactc cacctcaacg ggataaaaat tcccaaagga acccctcaaa gccttaccaa
    19021 cctgtacggc tgccccacga gaaacaaacc gcatggcttt cttctcctct gaacatgaaa
    19081 tgtccaagcc agtcacacca ataactacgg acctcagaaa cggcttatcc tctcttgtcc
    19141 catgtcttaa aataaacatc agccacctcc attctaaaaa tattgcttcc gcttgtttgt
    19201 caagtcgttg aaaaccatta aatggtcttt atccacaccc ttcatcagtc tggacataaa
    19261 gggtctgcca tatcttttct gaatatcagc agaagtcaaa ttggtggtaa tgattgtatt
    19321 tgaacgctta ttcaggatat tgtagagaat agtaaacgac cattcgctat ccttttccat
    19381 tcccaaatca tccaaaacca agaacttagc actggcaatt ttattgacca gaaactcctc
    19441 ctgactaaaa tcagctttaa tcttcatcaa caagtccgtc acgttgatga agatagcaat
    19501 ctctttcgtg tactcagata gagccttaac catcgcaaag gccaaatggc tcttacctgt
    19561 tccagcttct ccttgtaaca cgatgttgtt cctagcaccc tcagaccact cacgacaaat
    19621 cctctttgca aaaactagct tttctgcttc tttttcagtt ggtgtttcaa aattgtccaa
    19681 agtcgcattt ttcaaaacct catcataaag agaaaacttc tcaagatagt atttcctctc
    19741 tcgctcattc tcagcgtcgg ccaattcatt cactcttgct tgattttcct catgaatccg
    19801 ctcagattca cacatgcgac atacaacact ctcggtcctc aatatcttta tcaaagggat
    19861 gttatgcttt tcgcagaact cttcttgttg ttctgtattc ctacgataag ataaggcgat
    19921 ttcctcaaac acattgtcta ccatactagc cgacctccgc attcatgcca gctagccatt
    19981 tcagacaagc aggcaaccac ttgatgaatt ggttggtctg ctaaaagagt tttcttctcg
    20041 tagcttaacg gataatagtc aatctcgaat tgttcaatta gttctagtac ccccattcgt
    20101 ccttggcctc ctgttcttct ttcttatcct tgttcttctt ttccgattga cgaacctgtt
    20161 caacagtggt aacattgttc atctgccaat ttcttaaaat cccaccaata tatttgatgt
    20221 tcggctttcc tgagttaata gcagtcttca atgcttcttt caccaaatcc acattattct
    20281 catttagtag atggttgatt tcttcaattt caaatccaga taagagtcta cgaaactcag
    20341 attgaaaaag ttctaagata ttttcttcac taccactact agtagtagtt attcttttct
    20401 tattcttatc tttatctaat ctattcttat tcttatcttt atcttcttct agtgcgttac
    20461 cgtccgttac tgtaacgtta cctgtaacgt taccaagagc aagatttttc tgttttttac
    20521 ggtatttggc tacacggtta cgtgtctgtt ccttgatttt ctccattccg tcaacgtttt
    20581 gatgtttttc ccaatttggc aagctaataa taccatcgat aatctcaatc atcccaaact
    20641 gttcaaaaac tccaatagcc attcttactg tattcaatgg tctacgaaaa atagtagcta
    20701 acatttcatc tgtatagtga accttatcag tcatcatcaa caaaccatta ctgttatgtt
    20761 ttccagcaag tgtcaaaatc ttgaaccata tcactaagat ggcatcagga tcaggcaagg
    20821 catcaatcag gcaaatcttt tcatcgtcaa aaatatcggt tgtgattttt atccacttaa
    20881 tttcagacat acctagcacc ccacttccta cggttagcgc gatacttcat ccgcatatct
    20941 tcatagatgt acctgccttc cagctccatt ttttcaatct ttagcagctt atttttaagc
    21001 tccacatcac gatagtcctt agctagtttt tcatagtctg ttaggtattc tttgactagt
    21061 aatagatttt tataatcgtt ttcccatatc gtaataaaat gtcttgaagt tgattccctt
    21121 ccttccagtt ctttagcaat cataatcagg ttatccagcg attcaatcaa ttcttccatt
    21181 tcctgccctc ctcattacag aagtctgatt gcagactgtt tagattctgg caaagccaat
    21241 ggttcaggac gcaagcctac aggcggttca ttgtcgtagg taaagccctt gaacggacga
    21301 cgaatattct tgcggatttc ttgacgttca gcctctctac cacgttcgta agcatggtta
    21361 tagcctcgaa taatcataga cgcaaattct tgctcttctc gtctttcttc ttccttgcgt
    21421 tgttcctgca atttgatatg acggcaagcc cctgcaaatc caagcagtaa ggctccaacc
    21481 cccatcagct ggtctaaaat cggtggttca aacattttta tctccttatc ctctttttgt
    21541 gctataatat agtcaaataa ttttgctaag accttgtcca gaagcctttt agtaaagtta
    21601 ttatatttga ttagagagcc attctttgat ggctcttttt gaccatttct taccaggtaa
    21661 ttcctttgga aatcccttta agtaacgata attatctgaa aatgtggcat acttaattcc
    21721 tagaaattcg caggtagtgt tcacatccat caactctgga tagtggtcac tatctttttc
    21781 gatttcaacc aatctagtga ttgtgtcctt gataatggat ttaatccatt cagatagtga
    21841 aagtagaaca ttgtccatct ttttccctcc tacacttcgt cgaatgagtt caatttcatg
    21901 attttcatct tggtattggt gcttggctcc caagtcatcc agtaagctag agcggcatcc
    21961 gcatgcttct tgggtagcaa gtcatagcga ctaatatcga agtggtcttt aaagtcaatc
    22021 tcagcttgtc taaagactga ctgagcaaaa atcttatccg cataagcagg gctatcaata
    22081 ccacccaggc aagccacaac cctagcctta cgcttcttca agagcgattg agcatagcta
    22141 ggatgaatcg gttgctcact ctttagatag tcgatatctt ccagcatggt agcctgttgc
    22201 tcacgcaatt tcttttgacc agtgaataga gcgataaagg catcctcgtc caagtcctcg
    22261 cgaatgaaac cgccctgctt gcgaatagct ggcaagactt ctgatgtcac ccagcgcttg
    22321 aattccttag cctgaagcaa cttgctggat aagataagag agtagagacc agattcgttg
    22381 ataacggtaa cacctctatt tccaaaagta ccgttttggt agttttgacg atcttcatca
    22441 tctacgtgac ggttaatatc tcgactaccg ttttggtacc ccagaatatc cgctacatcc
    22501 ttcccgacaa accacggctc gtcatcaatt gtcaaagtac ggacttcctg cccgtgaaaa
    22561 ttaaaaattt cgttcataat attcctttct aaatttggta tactgaaaat aaaacgattg
    22621 gagaaatctt atggattatc aaattcttat tcaacctgca attagtgtca ttcttgcaat
    22681 aatctcaggt ttatggtcat atattgcatc aaaagctaac aataaagctg agattgaaaa
    22741 acaggccaaa gaacattcac atatcgtaga gaaacttgaa aaagaatttc attatcagat
    22801 agatactctc aaacaacaac acaccttgga acttgaaaaa gtcaaacaag ctcatgaatt
    22861 acggttacaa gaacttgaaa aggtatctca gattgatact gaaaccgaca aggctatgaa
    22921 gatgaatgat cttatctaca aaacttttac aggcgaagtt gatttggaca aagctttaaa
    22981 attagctgat aaagctaaca atcacaaaca aaaactaaat aaaaaattta ttcaaaagac
    23041 ttctaaaaaa tcataaatta aatttatttc taattctttc aagctcatca tcttgtattt
    23101 ttttatactc gttgatgcgc ttttttctgt ctcttttgct agcgtagtat gtagcaaaac
    23161 caatgataag attgattatg acaacaaagt aaaaccatac tatttcattc atctccaccc
    23221 tcctactcca gcaccttact gccgactacc aatcgtttaa cgacaacgtc catctcctta
    23281 aattcggcat tctctgcaca gtagcggacg ctctcgctga tgatgtgaca aatagatacg
    23341 ccgtactcgt tcgccagctc cgtagcaatc tcccaggcat ctttgtcaat ccgtgttact
    23401 ttttgcgctg cgttgttcat actatttcct catgctctaa ctattttccc aagggttctc
    23461 aatccctaaa acatctgcaa ctttttcctt aacagactca ctacctttgc catacttcag
    23521 caactctgaa ataactgatg atgctacaga tacttgtttt gctaactcag cttgagtcat
    23581 atcaagctca atcaaacgag ttttgatttt agccttgatt atctttagtt ctttactcat
    23641 ctttctcctt tctatttctt cgtttcactt tccagcgctc tgagttctat ctcatggctg
    23701 gcttgtttaa atagcttctc acacgctatt ttagcttctc tgtacgttgt gttctcgctg
    23761 atgaagtaat cagcaagttc gatgatttta tcttccattc aacctcctat atcagtctca
    23821 agactgaggt aatatcttcc taaattgcta taataatctt gattaggacc tctcaccgtt
    23881 ttagtcaaaa ttccaataga aaggaggaaa ttttatatgt caaaactcac taaagaagat
    23941 gttttacaag tttctcaaga aattatcaac gatgctattc cagttatcaa agatatgtta
    24001 gatgaggtat ttaaagaata cccaatcgac atggaaatta gaaaggctat tcttaatagc
    24061 gtccttgtcg ctcataaact cagtacagaa actacggttt cgttgctaac agaacttgta
    24121 aatgctcaag aaaactagtg tttcttagaa ttttttctac taattcaggg tctgccttta
    24181 cgagggtgga ctcttttttc ccactatacg gatatcgtct tggtctcatt tcctcacctc
    24241 cttttaaaaa attatctaaa aagttagcga atttcttgac aaaaaacaat ctatagttta
    24301 gaatttaatc atagagaaaa gacctactaa aagtaaggtt ctacctagaa aacggacgcc
    24361 aatcagtttc attaggcttt attttttagt tgtcttgttc gctaactctt tagcttacaa
    24421 ataatattct aaactataga ttgcgttttg tcaacatatt tacaatcaaa agtttaaata
    24481 ttttttgtca tgccttagaa aggttgataa atcaatgttt tctttgttcg aaaaaataaa
    24541 agaactttgc caaaatcgtg gaatttctat aaattctctt gaagaaacat taggatatag
    24601 tagaaataca atctatagta tgaaaaacaa aaaaccaaat gctgaacgtc ttcaagaaat
    24661 tgctgactac ttcaacgtgt ccacagatta tttacttggt cgcacggata atcctgctat
    24721 tgctggtgat tcaaaagagt acacttggca aggaaaggca ctaaatgttg aagagatggc
    24781 atctaatgtc atgatgttcg gcggtcgaga attaacagac gaaaagaaga aaatcatcca
    24841 gtctatcatt gaaggttatc tcaaagaagc tggtgattag aggtattgct tagtgactga
    24901 aaaagaaatt ataagtcatt ttcaggttcg cattgtcgat tttgacggtg agctaatacc
    24961 tgacgaactt ggattttacg aaaaagaaac caacacagct ttcttatcta ataaactcag
    25021 caaaaaagag agagttaagg tactactgca tgaactcgga cacaaagacc acacacgctt
    25081 agagtaccag aacgctcgcc tacgctgtga aaacgaagct gataggaata tgatccatca
    25141 tctcgtaaaa gacgcgatag aaagcttaga cgaccccaca gagtttgatt acctcaaatt
    25201 catgtcctac tacaatctaa aaaccatgac gaatgaagtc atggtaaaag aggaatactt
    25261 tgcattgatg gagtgaaagg agactcatat gtcttactcg tatgttgctt tagatgttga
    25321 aactgcgaat gactttcgcg gtagtgtttg ttctatcgga ttagtaaaat ttaaagatgg
    25381 aaatattgtt gatgcttttt acactttaat caatccagaa gaagagtttg atgatttcaa
    25441 tattttcatc catggcatta cacctgaaga tgttcttgat tcacctacat tcccagaggt
    25501 gagaaaggcg attgttgatt ttattggttc tgatatagtt gtagcccact ttgcacagtt
    25561 tgatatgggt gctcttaaag atgtatacca aaaatacgag ctggattttg ataatataga
    25621 atatatttgt tcgtatcgat tagccaaggt cgctctccct ggacaattga attacaaact
    25681 aaaaagacta gctaaaaatt tgaatattga gctagaccac cacaacgctt tatcagatgc
    25741 acgagcaagc ggattgattt tagaatactt attatctact aattcatttt ccgacctcaa
    25801 cgctttttta aaagaatata gctacaataa aactggctta cttggtcagt atggatttaa
    25861 aaggaaaaaa agttatcagt acaaagaaaa tcttatctat cagccaacag aagaagaaaa
    25921 ggcagcaatg aacccagacc attactttta cggtttgtac ttttgcttta ctggaaaact
    25981 cgagcgaatg actagaaaag aagctaacaa aactactgca ttagttggtg gtattcctga
    26041 aaaaggagtg actaaacaca ctaatatctt agttgtagga gaacaagatt ggagagtagt
    26101 cggtacagat gggttaagta gtaaaatgaa aaaagcacaa accttgttag aaaaaggtca
    26161 agatattgaa atcatgacag aaaatgattt tataagattg cttgaggagt aattaacaaa
    26221 aaataacaaa aaagctccac aatctccctc gccaaagttt gattgtgaag cccaccctta
    26281 taaaaaatca gccattaaaa aggcctcttt tctatactct attttacacc atgaaagggg
    26341 tgatgtcaat attctcaatg tttagacctt gtccagaagc tgataaacaa ggagaataca
    26401 atgaaatata ataaaacaaa atacccaaat atctattact atgagactgc taaaggcaag
    26461 cgttactatg tcagacgttc ttttttcttc cgaggtaaaa aaagagaaaa aagtaaaagt
    26521 ggtttcacaa ctctccctca agctcgcgca gccttggtag agcttgagca acaaattcaa
    26581 gaacaagaat taggtatcaa tacgaatcta acgcttgatc agtattggga tatctattct
    26641 gaaaagagat tgtcaacagg gcgctggaat gacacttcct actacctcaa tgacaatctc
    26701 tataagaacc atatcaaggc aaagtttggt tctatcctgc ttaaaaattt ggatagaaat
    26761 gagtatgaac tatttatcgc tgaaaagttg cagaaccata ccagatacac tgttcaaacc
    26821 ctcaattcca gcttcatggc attgctgaat gatgccgtga aaaatggtaa tctgctctca
    26881 aatcgcttga aaggtgtttt catcggccag agtgatatcc ctgctgcaaa caagaaagtg
    26941 actctcaaag agttcaagac ttggatagca aaggcagaag agattatgcc aaaacaattc
    27001 tacgctctga cctatctgac aatttttgga ttgagaagag gagaagtctt tggattgcgt
    27061 ccaatggaca tcactcagaa cgacagcgga cgggctatac tgcatcttag agacagtcga
    27121 agcaaccaga ccttaaaagg gaaaggaggg cttaaaacga aggattcaga gcgatatgtc
    27181 tgccttgatg atatcggaac agacctgatc tattatctga tagctgaagc ttctaagatt
    27241 aagcgaaagt taggaattat caaggaacag cacaaggatt atataactat caacgagaaa
    27301 ggtggtctca tcaatccaaa ccagctaaat agaaacttca atctagtgaa tgaagcaaca
    27361 ggattgcatg taacacctca catgatgcgc cacttcttca cgactcaaag cattattgca
    27421 ggggttccgc ttgaacaatt aagccaggcg ctgggccata caaaagtcta tatgaccgat
    27481 cgttacaatc aagtagagga cgaacttgct gaagcgacaa cagacctatt tcttagtcat
    27541 attcgctaaa aaaatccccg ccaattcccc gaccaaaatc cgaaaaatac cgaaaaatat
    27601 cgaaaaatta tttttagaat agtccccaaa agcctgaaat agagctaaaa aactccacct
    27661 gattcggtgg agttaaggga gattattatg aaaaagaaaa gtttaggata tttgttacaa
    27721 caagttagga ggtcttcttg taactgtcta tagtataccc gacctatctt aaacaaatct
    27781 taaaaatctc ttaggaccaa acactttcta aaatatttgt ttgttcacga ccaggaccta
    27841 ctgagaaagt agaaatacga acgccaacca attcactcac acgacgaaca tagttacgcg
    27901 cattctcagg aagatcttcc aaattgcgaa ctccggtaat atcttctgac caacctggca
    27961 actcttcata gataggcttg caacgtttca attgctcaag actagctgga tagtagtcaa
    28021 tacgttgacc gtcaagatca taggccacac agattttcac agtatccaaa ccgctcaaaa
    28081 catcaataga gttcaaagaa aggttagtaa taccagaaac acgacggcta tgacgcatca
    28141 caactgagtc aaaccaacct acacgacgtg gacgaccagt tgttgtacca tattcatgac
    28201 ccacttcacg gatacgttct cccacttcat caaacaactc agttgggaaa ggaccatctc
    28261 ctacacgact cgtataagct ttacatacac ctacaacctt gtcaatcttg cttggaccga
    28321 caccagaacc aattgtcaca ccaccagcta cagggtttga tgacgtaaca aatggataag
    28381 taccttggtc gatatctagc ataacacctt gtgcaccttc aaaaagcaca cgtttgccat
    28441 tatcaagcgc atcattcaag ataacagatg tatctatcac gtatttcttg atttgttgac
    28501 catattcgta atattcttca aaaatatcat cgaaaacaat cgctttactg tcatacaatt
    28561 tttcaaaaag acgattcttt tcagcaaggt tacgttctaa acgctcacgg aaaatatctt
    28621 tatctaaaag atctgcaata cgaattccaa cacgagcagc cttgtccata taagctggac
    28681 caattccctt aattgtcgta ccaatcttat tgtcgccctt agcttcttct tgcaagcgat
    28741 ccaactcgat atgataaggc aaaataacat gcgcacgatc agaaatacgc aagttatcag
    28801 ttgttacacc ttcctcatga agatagctca actcttttac aagagattta ggatttacaa
    28861 ccataccatt cccaatgaca gatatttttt cagggaagaa aatcccagat ggaatcaagt
    28921 gcaacttaaa tttcttaccg tcaatcacaa tcgtgtgacc agcattatca ccaccttggt
    28981 aacgtgcaat cacttctgca ttcgctgaaa ggaagtctgt aatcttccct ttaccttcat
    29041 caccccattg ggtacctaca acaacaactg aagtcataat tttgtctgag ccctcaggct
    29101 cttcctttct cacatacatg gcaggactct cacctgcaat tatatcttac aatttattat
    29161 aataaaaaat cgccttttta tcaagaagaa acaatagaaa gatttgctat ttccaactat
    29221 taaaaaatga tttagaaaaa ttactagcta tttactatta tctttccata aaagagtaaa
    29281 ttagttcgga aatttactaa aattacctca acaagaaata aaaccccgat tcattaccaa
    29341 tttttcaaga tacaaacgat aagcaacacg ataatggtaa acgataaaat ccttacgaca
    29401 accaatgcca tatctcacta aataataaat taaaaattta aaatgaacat gttcccagtc
    29461 aaaattatca ccaaatgtag gaccatactc ttcttcaata ctatcataga aattagt
//
LOCUS       DAVLGK010000027        29182 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLGK010000027 DAVLGK010000000
VERSION     DAVLGK010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29182
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.027"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            116..307
                     /locus_tag="VXE01_001301"
     CDS             116..307
                     /locus_tag="VXE01_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0750201.1"
                     /translation="MPDITNGREKVNDFLKDKGIKKTSLAIAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            319..1026
                     /locus_tag="VXE01_001302"
     CDS             319..1026
                     /locus_tag="VXE01_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEV0750202.1"
                     /translation="MNEVIKVTVNDNHEPIVSGRQLHEALGVKTEYKKWFSRMTEYGF
                     NENEDFLKVTQKCLTSSTGQNTTDHIIKLDMAKEIAMIQRTERGKQVRQYFIQVEKDF
                     NSPEKIMARALLMADQKVHKLEAQIEADKPKVLFADAVSASHTSILVGELAKLISQNG
                     YKIGANRLFSWMRENGYLIKRKGSDWNMPTQRSMDLKLFEIKETNVQHADGHITVNKT
                     PKVTGKGQQYFIDKFLN"
     gene            1212..1553
                     /locus_tag="VXE01_001303"
     CDS             1212..1553
                     /locus_tag="VXE01_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEV0750203.1"
                     /translation="MMVVLANHPNWQVYPDEIAKRKGVNRKTIDKYFKIFEEAGYLRK
                     IRKKPPGNGGSHIFRFFSDVKISDFQFDIMKQRLNLSIKRASMNYNSDIPKSEMSESE
                     MSESEMSDFGH"
     gene            1710..1976
                     /locus_tag="VXE01_001304"
     CDS             1710..1976
                     /locus_tag="VXE01_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750204.1"
                     /translation="METVQIVRIKDVIIEKISANDEELERIFGCSKRQAGDMRREMKK
                     LPSQQKYLRNDGQLVTIKGFDAYLQYRGSQSWKKEMAKTVKMTR"
     gene            2060..2512
                     /locus_tag="VXE01_001305"
     CDS             2060..2512
                     /locus_tag="VXE01_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750205.1"
                     /translation="MPNWAEGTLKLRGRRENVASALKEMLLGDEGATLEEEYDGTLLR
                     FKNEYDYFYINGTRRAFISSKDIEIWLDDDFVIIELEDFEQAWAALADNYTEISSKFD
                     VDIKIFTFEMGMEFTQEIEISKGEIIKNIVNENFTNYSWDVPFSRLGG"
     gene            2518..3213
                     /locus_tag="VXE01_001306"
     CDS             2518..3213
                     /locus_tag="VXE01_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEV0750206.1"
                     /translation="MADLTFAELQRKMQIEKQTKQGVKYPFRTAEDINNKFKSLDSGW
                     SVSFPEDDIIQKGDKLYYKAVAVAKRESDGTIEKAIGWAREEDVPIFHTQKGDVKQMQ
                     DPQWTGAVGSYARKYALQGLFAIGGEDVDEYPVEESQEQGQNNQQQKPNNQQAQGQNQ
                     VRYIDNIQYQEINDLINDIAKIKGMPFDTLANYVLSEKLKGLQDFHRVQVGDYEVLKN
                     YLTEQLAKAKRGN"
     gene            3216..4208
                     /locus_tag="VXE01_001307"
     CDS             3216..4208
                     /locus_tag="VXE01_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEV0750207.1"
                     /translation="MVKDVTNSLTEIKVDFQPAVINVDREAIEAQVAAAIAQYSGREV
                     TVDNYKEVYEERTRFNKLIGGLDTQRKDFNRQINEPAKDFDKWVKEKVIKPIEGVTDA
                     MSAGLNAIDEHERLMRVDVVRATFEDKCMVAGIEKSTFADKYDEYSLKKYFKTGKYEL
                     KKTTLDEMDGLVLSEFDALEEYKANKQAIQEQAQEYDLPADSYIRHLEDGKSLVDILK
                     MMKTDRDAEIARKEQKEAQEKAKAERLEEIAQSAKKNANANIKAYDAETGEILEQGTI
                     TPEPQNNAREVAKFEPSEPLVKLVRLELHGGLEQWENTQEYFEDNFIGFETLED"
     gene            4230..4406
                     /locus_tag="VXE01_001308"
     CDS             4230..4406
                     /locus_tag="VXE01_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750208.1"
                     /translation="MRCFYVSGKIADLDLGSEINAENSFMAAIEFVKRYTGLLKFGSN
                     EIKVSEVEEVQNDK"
     gene            4396..4941
                     /gene="ssb"
                     /locus_tag="VXE01_001309"
     CDS             4396..4941
                     /gene="ssb"
                     /locus_tag="VXE01_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0750209.1"
                     /translation="MINNVVLVGRLTRDAELRYTQSNIAVATFTLAVNRPFKNEAGER
                     EADFINCVIWRQSAENLVNWAKKGSLIGVTGVIQTRSYDNQQGQRVYVTEVVASNFQL
                     LESRNSQQNNQGHQDHHGGYQQQGYSNQGSSFQNGNSYGQQGSFLEGNTTNLVPDFTR
                     DNNPFGRPTNPLDISDDDLPF"
     gene            4967..6100
                     /locus_tag="VXE01_001310"
     CDS             4967..6100
                     /locus_tag="VXE01_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV0750210.1"
                     /translation="MKFLDLFAGIGGFRIGMESAGHECIGFCEIDKFARASYKAIHDT
                     KGEIELHDITTVSDDTIRGIGHVDVICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILKPRYLFLENVKGLLNHDRGNTFEVILSALDELGYDVEWQVLNSKDFGVPQNRER
                     VFIIGHSRKRGTRRVFPIGRANREFDFEPKIKIVGNTKNPNGTSQGTGSVVYDSNGLV
                     GTLCARDYKEPKQVAIPVLTPDRVNKRQNGRRLKKNGEPMFTLTAQDRHGILIKEATK
                     KGYAEATVGDSVNLSHPNSKTRRGRVGNQIANTLLTGESQGVVEPDFRIRKLTPKECW
                     RLQGFPDWAFDKAQEVNSNSQLYKQVGNSVTVNVISAIAQGLG"
     gene            6144..6347
                     /locus_tag="VXE01_001311"
     CDS             6144..6347
                     /locus_tag="VXE01_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750211.1"
                     /translation="MTKIEIVMVLTTLMSITWAAIVTIHAMQAIKKHKAKVDYYQKPQ
                     VQCEIARHVLKNKWYSDGGEVFR"
     gene            6401..6835
                     /locus_tag="VXE01_001312"
     CDS             6401..6835
                     /locus_tag="VXE01_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750212.1"
                     /translation="MDKKLIGLDLTHIADGGLQEKLDKELEKVFDNILDLNTDAKAKR
                     KVTITLTMSANEERTVVDTTMEVKSKFAPQNGVATTILIGRDFDTGQVHANELKSTVP
                     GQMYFDENGEILTDIGQPVAEIEQQAETKPDIIDFNKKKVGN"
     gene            6837..7574
                     /locus_tag="VXE01_001313"
     CDS             6837..7574
                     /locus_tag="VXE01_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750213.1"
                     /translation="MTTENLKAALEYAVELNEHGLEILTAADGTEYYDANKFNLKELD
                     PKRYPKTLELSTLTSLVDYLKTDLNNLKNQRLIVAVEKNDEVCVWSENDEIEHRTLLV
                     DVKARIPELSFGRFLSLEQFNIMLQSNFIDDNDRGTLLEFASALKIENGAEIEDNGVS
                     QVATVKTGVASLAKGKAPNPVTLRPYRTFSEVEQPASLFVFRIDKQANMALFEADGKR
                     WVADAVGNIASYLKEQLADQKHITVLA"
     gene            7591..7803
                     /locus_tag="VXE01_001314"
     CDS             7591..7803
                     /locus_tag="VXE01_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750214.1"
                     /translation="MSDYKQRMIEEYKQLKERTNKLSLMISNYYVGTLDFKLKCPIEL
                     LETQHYTMCAYLKILEQRAEIENIEF"
     gene            7814..8215
                     /locus_tag="VXE01_001315"
     CDS             7814..8215
                     /locus_tag="VXE01_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750215.1"
                     /translation="MKFEFSLPRNTKLKSLNMVINSNDRQHQTDKAKVTKRIRAFAYW
                     HTSMNKDKERAAFSPSNPCEVTVTIYSPTKSKLDPPNLYPTVKAIIDGMTDAGIWTDD
                     NHKVIKKLSFVYGGLSEEKGHYRLEFDIEEV"
     gene            8217..8423
                     /locus_tag="VXE01_001316"
     CDS             8217..8423
                     /locus_tag="VXE01_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750216.1"
                     /translation="MIEVNIKFDNFEAHGFYQDDTKLGKIRDAIISQMNNGHVVVLGE
                     DRGILLNPKVIKSVQFKVVEDNQI"
     gene            8472..8789
                     /locus_tag="VXE01_001317"
     CDS             8472..8789
                     /locus_tag="VXE01_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750217.1"
                     /translation="MMEELKQKVNAVYNWTVEDGKPKPPKQDLPQAVKDRVDYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWIGYAPSMAQVVIAVYLIY
                     GGN"
     gene            8791..9291
                     /locus_tag="VXE01_001318"
     CDS             8791..9291
                     /locus_tag="VXE01_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0750218.1"
                     /translation="MNIKALIKKYEELWNEHSPFYEPVPYTSMVELFLKELKQLDEPE
                     KVKVPQFMADWIDYFKKNGDWDLFQAMDYLFGKKEIREWLEYKNNQDLFARAWLDGYE
                     VEKEKRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEDAKFGWVFDCPGI
                     EIEEVE"
     gene            9291..9584
                     /locus_tag="VXE01_001319"
     CDS             9291..9584
                     /locus_tag="VXE01_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750219.1"
                     /translation="MTQTLEEGMKNQSKCIKIPMEIRPFDVGYRIVNKHGQALALKNG
                     ASIFDLPSLAEKAIKKEFSKDDPDFDIEKHFVEEVAIVNLSKFHSYFEEVIHD"
     gene            9584..9976
                     /locus_tag="VXE01_001320"
     CDS             9584..9976
                     /locus_tag="VXE01_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750220.1"
                     /translation="MTKKKIERLSVIHRREINWLKWYFLRDKKNPKRTILEQKIIVSH
                     IKTDRLEAKFLSNLKKSTEDFIDKSDPKYLRAIKEVYVYENMNVIGACQKILFYSPTQ
                     AYVLLNAWFNDYFRATYTELLENAILDK"
     gene            10042..11136
                     /locus_tag="VXE01_001321"
     CDS             10042..11136
                     /locus_tag="VXE01_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000425577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4417 domain-containing protein"
                     /protein_id="HEV0750221.1"
                     /translation="MEMLQIEYVDIKSIKPYHKNARHNDGEATEKVAASIKAFGFQQP
                     ILVDDNNIIITGHTRLKAALSLGIDTIPIAHAVNLTDEQIKAYRLADNRVAEYSTWDS
                     ELLNIELSQFETIDMAQFGFELSVTGFNFGNEEEQQEETENEEEDAEDFHRDTTINQY
                     NLFHYDDTRVEGFYNMPKIEGVDHIPKDFQGFNYVLNKPDYSSCVHFFLDDYQFERIW
                     QRPDFYIEKLLEFDSALAPDFSLYLDMPIAMQVWNIYRSRLIGQIMQDYGLTVIPTVS
                     WASEESFDFCFDGLPKNSTLAISTIGVKQNKEQFEVWKNGVTEMIKRLTPKRIVVYGG
                     KVEYDYKDIEVVYFENATTERMKESGTKTN"
     gene            11117..11863
                     /locus_tag="VXE01_001322"
     CDS             11117..11863
                     /locus_tag="VXE01_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750222.1"
                     /translation="MAQKLTKLKDIFKHVSSIDLGKEILFEDLELYNKETETSKQYQS
                     IEEAENDLSLMEKVNKINFTLGGGRGANFEKGKDGKYPGFRGAGGARDSGSSKALHPA
                     SLNNQGRFSSVEGTIQEFIKKHGGSRTEYSTAVDSQGFAHNYVHGGKNSVQILPISGG
                     FTAIHNHPNGSNFSSTDLHSFAALKGMNTLVATNSSKAYRITKGANFDAKGFDKAVSK
                     SRFTTKDYNKGADLWLKKNAKKYGYTYSYE"
     gene            12067..12522
                     /locus_tag="VXE01_001323"
     CDS             12067..12522
                     /locus_tag="VXE01_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein"
                     /protein_id="HEV0750223.1"
                     /translation="MPRDGTKNLKPVTERTKDEARAISSKGGKASGIARRKKADLKKA
                     FEILLSLDVTDSKIKKQLEEMGMAGNNEALLAFATFQQAVKGNQKATENIIKLTNTKD
                     KYDIQEQKERIKALKYENRERAEAEKGSSETIEIVDAWAEDVRGATDDL"
     gene            12512..13822
                     /locus_tag="VXE01_001324"
     CDS             12512..13822
                     /locus_tag="VXE01_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV0750224.1"
                     /translation="MTFNVQKNINPHFKSVWISSLPYNVLKGGRNSFKSSVIVLKLAY
                     MMIRYIIAGEAANIVVIRKVANTIRDSVFNKVWWALNLFGIAEQFTKTVSPFKIVHKT
                     TGSTFYFYGQDDFQKLKSNDIGNIIAVWYEEAAEFNDQEDFDQSNVTFMRQKHPRAKF
                     VQFFWSYNPPRNPYSWINEWFESIKTNKNYLAHSSTYLDDELGFVTEQMLEDIERIKE
                     NDYDYYRYLYLGEAVGLGNNVYNMSMFHAIDALPSDDKLIGISFALDGGHQQSATACC
                     AFGITAKGKVILLDTWYYSPAGQVVKKAPSQLSKEIYAYMRSVIEKYRVQALQYTIDS
                     AEGALRNQMFLDFGLKWHPVAKLRKVTMIDSFQSLLAQGRFYYLNTENNKIFIEEHKM
                     YRWDEKTIKSDNPSVIKEDDHTCDTTQYFVLDNAKLLGLRVGNV"
     gene            13835..15403
                     /locus_tag="VXE01_001325"
     CDS             13835..15403
                     /locus_tag="VXE01_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0750225.1"
                     /translation="MSLFQKVKDFFSRGRYYMQTSNLNSILEHPKIAVTQEEYDRIKR
                     NLVYYQSKWDDVQYKNTDGDIKSRPMNHLPIARTASKKIASLVYNEQATITTKNEILQ
                     KFLDDMLTNDRFNKNFERYLESCLALGGLAMRPYIDGDKVRVAFIQAPVFFPLESNTQ
                     DVSSAAILTKTIKSEGRKNVYYTLVEFHEWVTADGQETGSTNDKKYYRITNELYRSDV
                     NDVLGQRVNLSELDKYKNLEPVTVFENLSRPLFTYLKTPGMNNKDINSPLGLSIFDNA
                     KTTIDFINRSYDEFMWEVRMGQRRVIVPEHLTQRQYQRPDGTIDFRPRFDVEQNVYMQ
                     IGGSSMDAGGITDLTSPIRANDYILAISEGLKLFEMQIGVSSGMFTFDGQGMKTATEI
                     VSENSDTYQMRSSIVALVEQSIKELCVSMCELGKAVGVYSGEIPELDDISVNLDDGVF
                     TDRHAELDYWAKMVAAGFSTKKRAIGKTLNISDVEAEKELNAINSELLPMNDAELAIY
                     GMHDQNEEEADDKG"
     gene            15390..15563
                     /locus_tag="VXE01_001326"
     CDS             15390..15563
                     /locus_tag="VXE01_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750226.1"
                     /translation="MTKVKFGVTSVDYSASIEDTPTIKLGLIIRGSGRLDASSVIKKL
                     IKDVSELEYELEE"
     gene            15606..16757
                     /locus_tag="VXE01_001327"
     CDS             15606..16757
                     /locus_tag="VXE01_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor capsid protein"
                     /protein_id="HEV0750227.1"
                     /translation="MKKKRKQLTFNDQQFPLQMQGVGDIYEKLQIDIFDRMIKRLKER
                     GSIDLMRNPYIWQLEKLNDMHMLNEQNLKLISERTGIAERLLRDVIENEGLKVYKDTK
                     QQLEEDLNKIPEGEISNGVTDSLEAYSRQAVSDLNLINTTLPKSLQVAYKSIVEETVA
                     QVVAGTKTSDVALHDTIMKWQKNAFTGFVDKGGRHWKADSYARAIIKSTTYKVYNEMR
                     TRPAEELGVDTFYYSMKAMARPACSPLQGQIVTKGAGREIDGITIYSLLDYGYGTAAG
                     CLGIHCGHYLTPFIVGVHELPNLPDYLKNLTPEQAEENARIEAGQRGLERLIKTHKER
                     LHYAHTLQDDKMIQAERLKVRGYQTKIRNLINQHDFLTRDYRREKLYIS"
     gene            16896..17459
                     /locus_tag="VXE01_001328"
     CDS             16896..17459
                     /locus_tag="VXE01_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HEV0750228.1"
                     /translation="MAFTTEELLNLGLTEEQAKSVFALRGKELNEDKSALETIKQERD
                     SLKSQLQKAEEQVEHLKSLENISAEQKDAIDKLQAEYDKYKNEAAAELAQTKKVSAIS
                     LALKDTNAFNPDKLMKFIDVDAIQLDDNGKPQIDEVINGLKESDPYLFKAEESKPSPN
                     ILPQGNPAGEGTSDVDPFQAIIDGYGK"
     gene            17477..18358
                     /locus_tag="VXE01_001329"
     CDS             17477..18358
                     /locus_tag="VXE01_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEV0750229.1"
                     /translation="MPSNQNNAVRRYEKQYAGILETVFGVRAAFSNALAPIQILDGVQ
                     ENSTAFSVKTNNTPVVIGEYKTGENDGDFGDNSGAQSRFGGVTEVKYENTDVNYDYTL
                     TIHEGLDRYTVNNDLNAAVADRLKLQSEAQTRTVNKRIGKYLSDNATKTEALADFTDD
                     KVKALFNKLSAFYTNNEVTAPITVYLRSEFYNAIVDMASVTSAKGATISLDENGLPKY
                     KGFTLEETPAQYFETGVIAIFSPNGIVIPFVGISTARVIEAENFDGVKLQAAAKGGTY
                     TLDDNKKAIYKVTGTIV"
     gene            18369..18602
                     /locus_tag="VXE01_001330"
     CDS             18369..18602
                     /locus_tag="VXE01_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001240344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750230.1"
                     /translation="MALYKATKNLFFEQLNMDVIVDDIIKLDEDYAKEVNKKLKNAFP
                     DVKNVLELVDKNGTLEPEDAPSVDDASQATVED"
     gene            18645..19037
                     /locus_tag="VXE01_001331"
     CDS             18645..19037
                     /locus_tag="VXE01_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013794407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750231.1"
                     /translation="MTYLTQEEFDELGFDEVTDFEKLAKRAKIAIELYTNGIYQKDID
                     FEKEIAYRKSAVKLAMAFQIAYLDASGIMSADDKQLANSVSIGRTSISYSTSQSTLAG
                     QRFNLSMDAENALRQAGFSLVVGVAYDR"
     gene            19027..19419
                     /locus_tag="VXE01_001332"
     CDS             19027..19419
                     /locus_tag="VXE01_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV0750232.1"
                     /translation="MIDKRLLKGIDKRLLKDVLTIKKVADKNDYGDEVYSEPLTIKNV
                     RFDRSVGGSGNRNSKTGTGNSKTGTGNSKSRQKQGVIYLYPSLSFVTVDNSWMGAKVN
                     DGIGDYTINGFQTNYYDGEIFSQEIEVI"
     gene            19419..19763
                     /locus_tag="VXE01_001333"
     CDS             19419..19763
                     /locus_tag="VXE01_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV0750233.1"
                     /translation="MSIAIKVDLQKAKQKLSNESMTRGKIAVASKILLNNEQYIPLRG
                     GELRASGRIVGQGDAVVYGTVYARAQFYGANGIVTFRRYTTPGTGKRWDQVATSKHAE
                     EWARAFVKGMGL"
     gene            19763..20170
                     /locus_tag="VXE01_001334"
     CDS             19763..20170
                     /locus_tag="VXE01_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV0750234.1"
                     /translation="MRENDFQNVLLKHIKTLNLPVEPRFDYFEDDKDDLVINQIPGGK
                     VDREYMDGTQEVSLPFEIAVKAKKNSVANDTIWLVTSELAKIDLVLPSDNNSYEYMGM
                     EVSRPAMKGKDEQGYYYYTIEIVAKIVIERNKQ"
     gene            20167..20616
                     /locus_tag="VXE01_001335"
     CDS             20167..20616
                     /locus_tag="VXE01_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0750235.1"
                     /translation="MTRQKNALRGHFVAPYNGGTEPSTEDTWLELAKWISDVSDDTDE
                     KTDDQAYYDGDGVEETTVVSVKGAYTFEGTYDPDDKAQALIAGMKYKTGDDRKLWHKV
                     VSSDRKKQWVGAATATEIKAGSGAASDYEAFGCKLSYNSTPKETGIG"
     gene            20681..21169
                     /locus_tag="VXE01_001336"
     CDS             20681..21169
                     /locus_tag="VXE01_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750236.1"
                     /translation="MTDIQIELKRTGFPVKIGEVELWFDTSQESLMRFYDMEEELKRR
                     LVQYELDVVSANINNKIERDGVTKEVVAGAIELEKKQLEIQYDLIFGDGTFDKLYSIY
                     PDYNALNNALEQTAIMLHDKLEEVAEQHKTVVKERASHYLNKGKVTPIKNNKKQKKNK
                     KK"
     gene            21182..21751
                     /locus_tag="VXE01_001337"
     CDS             21182..21751
                     /locus_tag="VXE01_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750237.1"
                     /translation="MSMKLNDALITNFSIADKEYDIDLSFNKVLDVFEILKEDEMTRL
                     EQAQLIVHLLTGQELYDIKEVVDCWIYIKEHFLGIEKETVQYDLLGNPMPKAKGEEEQ
                     EKLIDFEQDAEYIYASFLQAYGINLLKVQNELTWTEFKALLNALPDNTIMQQIIEIRA
                     WKPEYGGDKNKMRKLQAKYSLGKEGEDNV"
     gene            21744..25025
                     /locus_tag="VXE01_001338"
     CDS             21744..25025
                     /locus_tag="VXE01_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEV0750238.1"
                     /translation="MSDGKVTIVVDVDGNKVKVLNDELDKTAQKGDRGSSSLKKFAVG
                     SAVFQLAAKGAELLGEALGGAIQRFDTLESYPRVMQAMGHSTEDVTRSTKKLAAGIEG
                     LPTTLNEVVGTAQRLTSITGDINKSTDLTLALNNAFLASGSSSADASRGLQQFSQMLS
                     AGKVDMQSWKTLQETMPYALQKTAESFGFAGQSAQNDFYSALKEGRITFNQFSSKLVE
                     LNGGVGGFAELAKTNSKGIQTSFGNLKNAVVKGVANTIKALDDLTKAATGKTIAENFD
                     ALKVIINAAFGVIVNVIKASTPVFQTLFSILGTGASVISFLTPAIIGLVAALVTMRAI
                     NQAVKTTKDLISAWKTFKTTATGAIQIINLMTAAQATCGSVTKAQLVANLANNGALTA
                     SNLLYGVLTGSISLQTAATIAATAATTAFKAALTALTGPIGLVVAGIGLVVGVCVTLW
                     QWLTAESEETKRLKSEQEELVKSTDQLTDSVKQSAKERQKNLESVKGNTESYQKLADE
                     IVQLSQKTNKTAADKKNLKKKIDALNASVSGLNLAYDKNSDSLSHNSDQIKARISAME
                     AESTWETSQKNLLDIEQKRAEIGEQLKKIAEQRKKWNEESNVSDSVRKERLQELNDKE
                     TELKNTQTELQTEYEKTSQVQQAASEAMAAAAENGSNRQVVAYENMSKSQQKAIDDMR
                     TKYNELLETTTNMFEQIKYKSAISVDEMIANLQKNQEAVNNWATNLNTLAERGVNEGI
                     LAKLQAMGPQGGLYVQELVNASDEKLATLNEVFTQGGESAMNGLTAGMDTGALGITDK
                     IKGIVQSQVSSLQEEIAAADFSSLGQEIPNGVSQGIEQGVSTAGESSKNMANDIKESF
                     TSEMDINSPSRVFNEYGGFITTGLAEGVDKGTNQPVSSVTNLANQIKKPFDSLQSDFT
                     YIGEMAMSGLNAGLWSGSGSVMATANSIAERVKATIKSALDIHSPSRAMRDEVGRFIP
                     QGIAVGIEADAGVVEKSMLRLKESMMIDTRPEIALGLNKKLGAQVTVKQSSKQTIAEK
                     IKVTMDKSSELLEKALDVAETAVRRPNEMYLNDGTLVARTGDKFAKYQSEQLRRDNRM
                     KGVLS"
     gene            25022..26536
                     /locus_tag="VXE01_001339"
     CDS             25022..26536
                     /locus_tag="VXE01_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEV0750239.1"
                     /translation="MTKIMTFNGVDMSKFFRITDIIRPIGNKRSVSTDNAPLLGVNIQ
                     QVKIGEKEHIIKFDIKTTNAIEMEQLKHDLAGILNVLEPVKITYGDEPDKYYMGLPVD
                     EITPENLTRWFQRSELKIIIPDGVAHSTTLKNFDIDTNETSAPDRIVFNLTNTGTEPA
                     YPIIRIKHNSENGYIGVVNNRAAFELGNREEADTEKYRDSETLIDYRGTNILKGFQNG
                     TKGVAVTNDNKERLVGTLSTTSMWGRNHIELSNRGTVEKNRNNAQSLTWAIPVDSSGE
                     VGSLNDYLLWRQVFMAAVANQYGFIKVTVSDTDGNFLYGVETYKRYQTLDCEYSFFTT
                     DGKGGYKFIKWWYFTGTGAQVGKLDPFSAEKGWSELKRNDDRVQVFFDGSHYDFIIPE
                     IKDKKSAKIHITLGALRDWPLISHMYVDEFMYRKDFVTKSRDIPNRYPIGSNVVINSE
                     DDSVYIDGISKVSEVVDGSHWPAIPPGKSQLELYFSRFVKKKPTVTIEFEERWI"
     gene            26538..>29182
                     /locus_tag="VXE01_001340"
     CDS             26538..>29182
                     /locus_tag="VXE01_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0750240.1"
                     /translation="MLLTIHDANLQKVAFIDNEKQGTLNYYDDTWTRSLATGSSTFEF
                     TVFKKAVKSDLPLAKAYHHLNEHAFVSFKYKGKSFVFNIIIVEENEQTIKCYCENLNL
                     ELINELANPYKSNKAMTFKEYCEAMDLLNYTHLSIGINEISDYKRTLEWEGQETKLAR
                     LLSLAKRFDAEIEFDTQLNADSTIKKFSVNVYHENDDNHQGVGRVRNDVIVKYGKNIH
                     SITRKVDKTGIFNTIRPTGKMPTVEEEPSGDKGSKSETVKNADGSTTKTTISTASDGT
                     KSKTIVHTKVTKLADKTRITTTTTTRSDGSIEQTVTTSKKGGASTSETKVLKKPNPKE
                     KTNTTEDVLTIEGLDEWEVKNEKGIVEFYQRGQALYAPISMQLYPSTFTHSTGELDQW
                     TRKDFHFETDEPNELRRLGYLKLKKYCYPAITYEVDGFVDADIGDTVKVHDDGFAPLL
                     MIQARVTDQKISFTNPVRNKTIFDNFKALENKLSADIQSAFERLFEAAKPYTIKLSTD
                     NGVIFKNQIGQSLVTPTLYKGGKPVVVGVTWRWALDGEVTTGMTYLVRGSNVTDTVTL
                     TVAAYIGNKEVAVDEISLVNVADGKLGTPGTPGRDGRTPYVHTAWANNATGTDGFSLD
                     SSINKLYIGIYTDFEPNDSTDPKKYKWAKVKGDKGEKGDKGEPGQRGLDGLQGARGEQ
                     GLPGRNGADGRTQYTHIAYSNSADGTKDFSVSASDRAYIGMYVDFNSADSNTPSDYNW
                     TLVKGADGANGVAGKAGTDGRTPYLHIAYATSNNGSQGFSTTDSTNKTYIGTYTDYTQ
                     ADSTDYRVYKWTLIKGADGTGISNVTNYYLATTVSTGITRTSAGWTTTPQPITSDKRY
                     LWNYRVELYTNGTSKTTEPTVIGVHG"
BASE COUNT        10267 a         4752 c         6462 g         7701 t
ORIGIN      
        1 tttattatgc tttcatttta gacgaacatc taaaaaaagt caagcgaaaa gataaaaaat
       61 agttaaattt ttagttgttt cttatttaca aaataagtaa aaaggaggaa cacatatgcc
      121 agatatcaca aatggtcgtg agaaagtcaa tgattttctg aaagacaaag gtattaaaaa
      181 aacaagtcta gcgattgctt atggctttaa acgacaggaa gtaacaaaca ttctgagtgg
      241 gacgacgaag ggaccacgag cgaacagttt cattcttcaa gtgattgaag attatgggat
      301 tgagtaggag ggaataacat gaatgaagtt attaaagtga ctgtgaatga caatcacgag
      361 ccgattgtat ctggtcgtca attgcacgag gcgttgggag ttaaaacaga atataagaag
      421 tggtttagtc gcatgactga atacggcttt aatgaaaatg aggacttttt aaaggtgacc
      481 caaaaatgtc tcacctcttc aacaggtcaa aatacgactg accacatcat caagctagac
      541 atggccaagg aaattgctat gatccagcgg acggagagag gcaagcaagt ccgacaatac
      601 tttatccaag tagaaaaaga ctttaatagc cctgagaaga ttatggcaag agcattgctc
      661 atggctgatc agaaagtcca caagctggag gctcagattg aagcggacaa acccaaagtc
      721 ctctttgcag acgcagtaag tgcaagccat acatctatct tggttggcga acttgccaag
      781 ctcattagcc aaaacggcta caaaatcggt gccaatcgcc tcttttcttg gatgcgcgaa
      841 aatggctacc tgattaagcg caaaggctca gattggaaca tgccaaccca acgtagcatg
      901 gacttgaaac tctttgaaat caaggaaaca aacgtgcaac acgcagatgg acatatcact
      961 gtgaacaaga caccaaaggt cacaggcaaa ggacaacagt attttatcga taagttcctt
     1021 aattaggaat acctgacagg ttagaaagta gaaagaatga ttgaaaataa gtgaagagaa
     1081 aggagactgt atgacagact ttaaaaattt agattgtcaa tttatctttc aagaatgcga
     1141 ctgaaaatta tactgctgtt agtaatagtt ttatcaacga tcctgcgctg gattttacag
     1201 cggttggcat catgatggta gtgctggcta atcacccaaa ttggcaagtc tatccggatg
     1261 agatagctaa aagaaaaggt gttaaccgaa agacaatcga taagtatttc aaaatctttg
     1321 aagaggctgg atatttacga aaaatcagaa aaaaacctcc tggaaatgga gggagtcata
     1381 tattcagatt cttttcagat gtaaaaatat ctgatttcca attcgatatt atgaaacaga
     1441 gattgaacct atctatcaaa agggcgtcta tgaattataa ttctgacatt ccaaaaagtg
     1501 agatgtcaga aagtgagatg tcagaaagtg agatgtcaga ttttgggcac taataaatac
     1561 taactaacaa caagtattaa ataacaataa atactaacta acaacaagta ctactcttaa
     1621 taaataaaag agagtataca aaaaagtatc tgagaaactc agacactttc taaaaaaatc
     1681 taacttaatt atagcatgaa aggggaaaaa tggaaacagt tcaaatcgtg agaattaaag
     1741 atgtgatcat cgagaagatt tctgcaaacg atgaagaact agagcgcatc tttggatgtt
     1801 caaaacggca agcgggagat atgaggcgag agatgaaaaa attgcctagt cagcaaaaat
     1861 accttagaaa cgatggtcag cttgtcacaa tcaaaggttt tgatgcttat ctgcaatatc
     1921 gaggcagtca atcatggaag aaagaaatgg ctaaaaccgt taagatgaca cgatagcaga
     1981 ataataacta ctaacaaata acaaactcat acttatagat aataagggaa ttacagagtt
     2041 tttaaaggag gaaagaaata tgccaaattg ggcagaggga actcttaaat taagaggcag
     2101 acgcgaaaac gttgcatcag ctttaaaaga aatgctatta ggagatgaag gcgcaacgct
     2161 tgaagaagaa tacgatggca ctctactaag atttaaaaac gagtatgatt atttttatat
     2221 aaacggtaca agacgtgcgt ttatttctag taaagatatt gaaatttggt tggatgatga
     2281 ttttgtgatt atcgaacttg aagatttcga acaagcatgg gcagcattag ctgacaatta
     2341 cacagaaatt tctagtaagt ttgatgttga tattaaaatt ttcacttttg aaatgggtat
     2401 ggaatttaca caggaaattg aaatttcaaa aggtgaaatc atcaagaata ttgtaaacga
     2461 aaactttact aactattcat gggatgtgcc ttttagtaga cttggaggat agataatatg
     2521 gctgatttaa catttgcaga attacagcga aaaatgcaaa tcgaaaaaca aacgaaacag
     2581 ggagtgaaat atccgtttag aaccgcagag gacataaata ataaatttaa gtctttggat
     2641 agcggttgga gtgtatcatt tccagaagat gacatcattc aaaaaggtga caaactgtat
     2701 tataaagcgg tagctgttgc taaaagagaa agtgatggca cgattgaaaa agctattgga
     2761 tgggctagag aagaagatgt accaattttt cacacacaaa aaggggatgt gaaacagatg
     2821 caagatccac aatggacagg tgcggttggt tcttatgcta gaaaatatgc tttacaaggt
     2881 ttatttgcca ttggaggtga ggatgttgat gagtatccag tagaagaaag ccaagagcaa
     2941 ggacagaata atcagcaaca gaaaccaaac aaccagcaag cccaaggaca aaatcaagta
     3001 aggtatattg acaacattca gtatcaagaa attaacgacc ttataaatga tattgcaaaa
     3061 attaaaggga tgccgttcga tacgcttgct aactatgtac tatctgaaaa attaaaaggt
     3121 ttacaagatt ttcatagagt acaagttggt gactacgagg tattgaaaaa ctatttaact
     3181 gaacaactag caaaagcaaa gagaggtaat taaacatggt aaaagatgta actaatagct
     3241 tgacagaaat caaggtggat tttcaacctg cagtaattaa tgttgaccgt gaggcgatcg
     3301 aggcacaagt agccgcagcc attgcacagt atagcggtcg cgaggttact gttgataatt
     3361 acaaagaagt ttatgaagag cgaacccgct ttaataagct gattgggggc ttagacactc
     3421 aacgcaaaga ttttaaccga caaatcaatg agccggcaaa agactttgat aagtgggtca
     3481 aagaaaaagt catcaagcct attgagggcg taacagatgc tatgtcagca ggacttaatg
     3541 cgattgatga acatgaacga ttgatgcgcg tggatgtcgt gcgtgctaca tttgaggata
     3601 agtgtatggt cgcagggatt gaaaaatcca cattcgctga caaatacgat gagtacagcc
     3661 tcaagaaata ttttaaaaca ggcaagtatg agctgaaaaa gacaacactt gatgaaatgg
     3721 atggcttagt actttcagaa tttgatgccc tggaagaata caaggctaac aagcaagcta
     3781 tccaagagca agctcaagag tacgatttgc cagctgatag ctatatcaga catcttgaag
     3841 atggtaagag tcttgttgat atactcaaga tgatgaaaac tgaccgagat gctgagattg
     3901 cacgcaaaga gcagaaagag gctcaagaaa aagcaaaagc tgaacgactt gaagaaattg
     3961 ctcaatcggc caagaaaaat gctaatgcga atatcaaggc ttacgatgcc gaaacaggcg
     4021 agattttgga acagggtaca attacaccag aacctcaaaa caatgcgcga gaggtggcaa
     4081 aatttgagcc tagcgagcct ttggtcaaat tagtacgtct tgaattgcac ggtggtttag
     4141 aacagtggga aaatacacaa gaatattttg aggataactt tatcggtttt gaaactttgg
     4201 aggattaagt agaataagga gtcagaccta tgagatgttt ttatgtcagc ggtaaaattg
     4261 cagatcttga tttggggtca gaaatcaatg cagaaaattc atttatggcc gctattgagt
     4321 ttgtgaaacg atataccggc ttattaaagt ttggttcaaa tgaaatcaag gtatcagaag
     4381 tagaggaggt gcaaaatgat aaataacgtt gttttagtag ggcgacttac aagagatgcc
     4441 gaactgagat acacgcaatc taatattgcg gttgctacgt ttactcttgc tgtaaaccgt
     4501 ccatttaaga acgaggctgg agagcgtgag gctgatttta tcaattgcgt tatctggaga
     4561 cagtcagctg aaaatcttgt taattgggct aaaaaaggtt ctcttatcgg agttacagga
     4621 gtaattcaaa cacgtagcta tgataaccag caaggtcaac gtgtttatgt cacagaagtt
     4681 gttgccagta attttcaact gttggaaagt cgtaacagtc agcaaaataa tcaaggtcat
     4741 caagaccatc atggcggtta tcagcagcag ggctacagta atcaaggcag ttctttccaa
     4801 aatggaaata gttacgggca acaaggcagt ttccttgagg ggaacacaac aaatctagtt
     4861 cctgatttca cccgtgataa caatccattt ggcagaccca caaatccatt ggatattagt
     4921 gatgatgatt taccgtttta gcgaaagggg atattctagt taagttatga aattcttaga
     4981 cttatttgct ggcattggag gttttaggat cggcatggaa tcagccgggc atgaatgtat
     5041 aggattttgt gaaatagaca aattcgctag agctagttat aaagctatac acgatacgaa
     5101 aggagaaatt gaattacatg acattacaac agtatcagat gacactattc gaggaatcgg
     5161 acatgttgat gttatctgtg gaggatttcc gtgccaggct ttcagcattg caggaaacag
     5221 acgaggattt gaagatacaa gaggaactct cttctttgaa atcgcaaggt tcgcatctat
     5281 tctcaaaccc agatatctat tccttgaaaa cgtcaaggga ctcctcaacc acgacagagg
     5341 aaataccttt gaggtcatcc tctcagcgtt ggatgaactg gggtatgatg tggaatggca
     5401 agtgcttaac agcaaagatt ttggagtccc ccaaaatcgg gaacgtgtgt tcattatcgg
     5461 acattctaga aaaagaggca ccagaagagt ttttcctatc ggaagagcaa atagagaatt
     5521 tgattttgaa ccaaaaataa agattgttgg taacactaaa aatccgaacg ggacaagtca
     5581 agggactggg agcgttgttt acgactcaaa cggtttagtc ggtacgcttt gcgctagaga
     5641 ttataaagag ccaaaacaag tagctatacc agtattgaca cctgatagag taaataaacg
     5701 acagaatggt agacgtttaa aaaaaaacgg tgagcctatg tttacgctga cggcacaaga
     5761 ccgtcatggg attttaatta aagaagcaac aaaaaaaggt tatgcagagg ctacagttgg
     5821 tgatagtgta aacctatctc atccaaactc taaaacaagg cgaggtagag ttggtaatca
     5881 gatagcaaat actctcttaa ctggagagag tcaaggtgtg gttgagcctg attttaggat
     5941 taggaagcta acacctaaag aatgctggag gttacaaggt tttcctgatt gggcttttga
     6001 taaggcgcag gaggtcaact ctaacagtca attatacaag caagtaggca atagtgtaac
     6061 agtaaacgtt atttctgcaa tagcacaggg tttaggatga aattaatcct atttaaacca
     6121 atttgaaaag gaaacagaaa aaaatgacaa aaattgaaat cgttatggta cttacaactt
     6181 tgatgtctat cacatgggca gcgattgtta caattcacgc tatgcaagct attaaaaagc
     6241 acaaggcaaa agtggattat tatcagaaac cacaagtgca atgtgagatt gcacgtcatg
     6301 tacttaaaaa caaatggtac tcagatggtg gggaggtgtt tagatgaaag tatttgatgg
     6361 cgctatttca aattagctta atttaaagca ggaggacaat atggataaaa aacttattgg
     6421 gttagatcta acccacattg cagatggagg attacaggag aaactagaca aagagcttga
     6481 aaaagtcttt gataacatcc ttgacctaaa tacagatgcg aaagcaaaac gaaaagtgac
     6541 tatcacactt acaatgtcag caaatgaaga gcgtacagtt gttgatacta ccatggaggt
     6601 gaaatcaaaa tttgcgcctc aaaatggagt agctacaaca attcttattg ggcgtgattt
     6661 tgatacaggg caagtacatg ctaatgagct aaaaagtaca gtacctggtc aaatgtactt
     6721 tgatgaaaac ggagaaattc tgacggatat tgggcaacca gtggcagaaa ttgaacaaca
     6781 agcagaaaca aaaccagata ttattgattt caacaaaaag aaagtaggta actaatatga
     6841 caacagaaaa tcttaaagca gcattggaat acgcagtaga actaaatgag catggtttgg
     6901 aaattttaac agctgcagat ggaacagagt attatgatgc caacaaattc aacctcaaag
     6961 aacttgaccc taaacgctat cctaaaactc tggagctatc aaccttgaca agccttgttg
     7021 actatctcaa aacagaccta aacaatttga aaaaccaacg cttgattgta gcagttgaga
     7081 aaaacgatga ggtttgtgtg tggtctgaaa atgatgagat cgaacatcgc acattgcttg
     7141 ttgatgttaa ggcacgcatc ccagagttat cttttggccg tttcctatca ttggaacagt
     7201 tcaatatcat gttgcaatca aactttattg acgataacga tcgtggcaca ttgctagaat
     7261 ttgctagcgc attgaaaatt gagaatgggg ctgaaattga agataatgga gtatctcaag
     7321 tagcaacagt taaaacaggg gtggcaagcc ttgctaaagg caaagcacct aatccggtta
     7381 cattgcgccc atatcgtaca tttagcgagg ttgagcaacc ggcaagccta tttgtcttta
     7441 ggattgataa gcaagccaat atggctttat ttgaggcaga tggtaagcgt tgggtagctg
     7501 atgcagtagg aaacattgca tcctatctaa aagagcaact agcagaccaa aaacatatca
     7561 cagtattagc ataagaaagt ggaaattaaa atgagtgatt acaaacaacg gatgattgaa
     7621 gaatacaaac aattaaaaga gcgcaccaat aagttaagtt tgatgattag taactattac
     7681 gtaggaacac ttgattttaa actaaaatgt cctattgagt tacttgaaac tcaacactat
     7741 acaatgtgtg catatctcaa gatccttgaa cagcgtgcag aaattgaaaa cattgagttt
     7801 taaggtaatc aaaatgaaat ttgagttttc tttgcctcgg aatactaagc taaaatctct
     7861 aaacatggtt atcaatagta atgacagaca acatcaaaca gataaggcta aagttactaa
     7921 acgcattaga gcttttgctt attggcatac atcgatgaac aaggataaag agagggctgc
     7981 ttttagcccc tccaaccctt gtgaggttac agttacaatt tacagcccta ctaagtcaaa
     8041 acttgaccca cctaatttat atccaacagt caaggctatc attgatggca tgactgatgc
     8101 aggtatttgg acagatgata atcataaggt tatcaaaaag ttatcctttg tttatggtgg
     8161 attaagcgag gaaaaagggc attatagatt agagtttgat atagaggagg tttaaagtga
     8221 ttgaagttaa tataaaattc gataattttg aagcgcatgg cttttaccaa gatgatacta
     8281 aactaggaaa aattagagat gcaatcatat ctcaaatgaa taatgggcat gtggttgttt
     8341 taggggaaga tagaggtatt ctattaaatc ctaaagttat aaaaagtgta caatttaagg
     8401 ttgtagaaga taaccagatc taatcgtttt ttgaccttta gagaatctga gttattttga
     8461 ggagttggaa gatgatggaa gagttaaagc aaaaagttaa tgcagtatac aactggacgg
     8521 tagaagacgg gaaacccaaa cctcccaagc aagatttacc acaagcagtg aaagaccggg
     8581 tggactattt ttgggaaatg gcagaagatg gtatgacgtt tatgggagcg atggaatgca
     8641 tcttcgctga tgaaaagcct accgactatg atttgggagc tactaagggt tggttgccaa
     8701 aatctaagga gtttgatgat tggattggct atgcgccaag catggctcag gtagttattg
     8761 cagtttattt gatttatgga ggaaactaag atgaatatta aagcattgat taagaagtat
     8821 gaagaattgt ggaatgaaca cagccctttt tatgaacctg taccttatac ttcaatggtt
     8881 gaactttttt tgaaagagtt gaaacaacta gacgaaccag aaaaagtcaa agttccgcag
     8941 tttatggcgg attggattga ttatttcaaa aaaaatggtg actgggattt gtttcaagcg
     9001 atggattatt tgtttggaaa aaaagaaata agggaatggc ttgagtataa aaacaaccaa
     9061 gacctcttcg ctcgtgcttg gcttgacggc tacgaggtcg agaaagagaa gcggtatttg
     9121 gtgactttaa aaaataggca gcctttggtc aaatcgcaat cagggagtac tctttatttt
     9181 agtcaagata taacagctag gaattataaa ggtactcaaa aagaactaga agacgcaaag
     9241 ttcggctggg tatttgattg cccagggatt gagattgagg aggtggagtg atgacacaaa
     9301 cacttgaaga aggaatgaag aatcaaagta aatgcataaa aatcccaatg gaaatcagac
     9361 cgtttgatgt gggttatcga atagtaaata aacacggtca agcgcttgct ttaaaaaacg
     9421 gagcaagtat attcgattta ccatcactag ctgaaaaagc tattaagaaa gagtttagta
     9481 aagatgaccc agattttgat attgaaaaac atttcgttga agaggttgct attgtcaatt
     9541 taagtaaatt tcatagttat tttgaggagg tgatacatga ctgatgacga agaaaaaaat
     9601 agagcgcttg tcagttatcc atcgcaggga aatcaattgg ctaaagtggt attttttgag
     9661 ggataagaaa aatccaaaga gaaccatttt ggagcaaaaa attatagttt ctcatatcaa
     9721 aactgatagg cttgaagcta agtttttaag caacttaaaa aaatcaactg aagattttat
     9781 agataagtct gatcctaaat atttgcgggc aataaaagag gtttatgttt acgaaaacat
     9841 gaatgtcatt ggagcttgtc aaaaaatact attttatagt ccgactcaag cctatgtatt
     9901 acttaatgcg tggtttaacg attattttcg tgcgacttac acagaattac tagaaaacgc
     9961 catcttagat aaataaccgt aaaaaatcca aagcttatgt atctataatc aagatatata
    10021 agctttttcg aaaggagaga tatggagatg ttacagattg aatatgtaga tataaaatcc
    10081 attaaaccat atcacaaaaa cgctaggcat aatgacggag aggcaacaga gaaagttgct
    10141 gcatccataa aagcttttgg ttttcagcaa cctatcttag tagatgataa taacatcatt
    10201 attacaggac atactaggct aaaggctgct ctttctttag gtatagacac aatacctatc
    10261 gctcacgctg taaacctcac agatgagcag ataaaagctt atagactagc agataatcga
    10321 gttgctgagt attcaacgtg ggactcagaa ttattaaata ttgagctttc tcaatttgaa
    10381 acaatagata tggctcagtt tggttttgag ttatcagtta cagggttcaa ctttggtaac
    10441 gaggaggagc agcaagagga aactgaaaac gaggaggaag atgctgagga ttttcacaga
    10501 gacacaacta taaatcagta caatcttttt cattatgacg atacaagggt tgagggtttt
    10561 tataacatgc ctaaaatcga gggcgtggat catattccta aagattttca aggctttaat
    10621 tatgttttaa ataaaccaga ttacagctca tgcgtgcatt ttttcctaga tgattatcaa
    10681 tttgaaagaa tatggcaaag accagacttt tacattgaaa agctgctaga atttgatagc
    10741 gccttagctc cggattttag cttatatctt gatatgccta tcgctatgca agtatggaac
    10801 atttacaggt caaggctgat aggtcagatt atgcaagatt acggccttac agttatccct
    10861 actgtatcgt gggctagtga ggaaagcttt gatttttgtt ttgacggctt gcctaaaaac
    10921 tcaacgctag caatcagtac aataggcgta aagcaaaaca aagagcagtt tgaggtatgg
    10981 aaaaatggag ttactgagat gataaaacgg ttgactccaa aaagaattgt agtatatggc
    11041 ggaaaagtgg aatacgatta taaagatata gaggttgtat attttgaaaa tgcaacaacg
    11101 gaaaggatga aagaaagtgg cacaaaaact aactaaacta aaagatattt ttaaacatgt
    11161 ttcaagtatt gatctaggta aagagatttt atttgaagat cttgagcttt acaataaaga
    11221 aacagaaaca agcaaacaat accaatctat cgaggaggca gaaaatgacc tatctttgat
    11281 ggaaaaagta aataaaatca atttcactct aggcggtgga cgtggtgcaa attttgagaa
    11341 agggaaagac ggtaagtatc cgggttttag aggtgctggt ggtgcaagag atagtgggag
    11401 ctcaaaagcc ttacatccag catctttaaa caatcaaggg cgcttttcaa gtgttgaggg
    11461 aactatccag gaatttatta aaaaacacgg tggctctaga acagaataca gtacagcagt
    11521 tgactctcaa ggctttgctc ataattatgt acacggtggg aaaaacagcg tacaaatttt
    11581 gcctatctct ggtggattta cagcaataca taaccatccg aatggcagca atttctcaag
    11641 tacagattta catagctttg cagcattaaa aggtatgaat acactagttg caacgaatag
    11701 ctctaaagcg tatcgaatta caaaaggggc taactttgat gctaaaggct ttgataaagc
    11761 tgtgagcaag tcacgtttta ctacaaaaga ttacaataaa ggagctgacc tatggctcaa
    11821 gaaaaacgct aagaaatacg ggtacactta ctcatacgag taaaagaaaa gaggctaagg
    11881 tatgggtggt agaggagcaa aattaaactt gtcaacaacg aaaatgacaa ctcaaaatat
    11941 agagacttga ttaacaaaat cgaaaagtta ttaggaatag cgtaaaacat cccctttttt
    12001 aacatataca atgaaatcat aagtataaaa tgcttgtgat ttttttgttt gaaaggaggg
    12061 tggaaattgc ctagagatgg aactaaaaat ttaaaaccag ttacagaacg aaccaaagat
    12121 gaagcaagag ctattagctc aaaaggaggt aaagcatctg gcatagcaag aagaaaaaaa
    12181 gctgatctaa aaaaagcatt tgaaatcctc ttatctttgg atgtgacgga tagtaaaatc
    12241 aagaaacaac ttgaggagat gggtatggct ggcaataacg aggctttgct agcctttgca
    12301 acctttcagc aagctgtaaa aggcaatcag aaagcgactg agaacataat caagctgaca
    12361 aatactaaag ataaatacga tatacaagaa cagaaagagc gtattaaagc actcaaatat
    12421 gaaaatagag agcgtgctga agctgagaaa ggctcaagtg aaactatcga gatagtggat
    12481 gcatgggctg aagatgtgag gggggcaacg gatgaccttt aatgtccaga agaacatcaa
    12541 ccctcatttc aaatctgttt ggatttctag cttaccttat aatgttttga aaggtgggcg
    12601 taactctttt aaatcatcgg ttattgtact taaactagcg tatatgatga taaggtatat
    12661 tatcgctgga gaggcggcca atatcgttgt tatccgtaag gtggccaata ctattagaga
    12721 cagtgttttc aataaagttt ggtgggcatt gaaccttttt ggtatagctg agcagttcac
    12781 aaaaacagtt agcccgttta aaatcgtaca caaaacgacc ggctcaacat tttactttta
    12841 cggacaagat gactttcaaa aactcaaatc aaacgacatt ggaaatatca tagcggtttg
    12901 gtatgaagag gctgctgaat ttaatgacca agaggacttt gaccaatcaa acgtgacgtt
    12961 catgaggcag aaacacccac gcgccaagtt tgtacaattc ttttggagtt acaatccacc
    13021 tagaaatcca tatagttgga tcaatgaatg gtttgagagc atcaaaacga ataagaacta
    13081 tttagctcac tcaagcacct atcttgatga tgaactcgga ttcgttactg agcagatgct
    13141 agaagatata gagcgtatca aagagaatga ctacgattat tacagatact tatatctagg
    13201 tgaggcagtg ggattaggta acaacgtgta taacatgagt atgtttcatg ctattgatgc
    13261 tttgcctagc gatgataagc tgattggcat atcatttgcg ctagatggcg gacatcaaca
    13321 gtcagcaacc gcttgttgcg cttttggaat aacagctaaa ggtaaggtta tattattaga
    13381 tacttggtat tattcaccag ctggacaagt ggtaaagaaa gcgcctagtc agttatctaa
    13441 agagatatat gcttatatgc gatcagttat tgagaagtac agagtacaag ccttgcaata
    13501 cacaatagat agtgctgagg gagcgttaag aaaccagatg tttcttgact ttggtttgaa
    13561 atggcatcca gtcgctaaac ttagaaaagt gactatgatt gacagttttc aatctttgct
    13621 tgctcaaggt cgcttttact atctcaacac cgaaaacaac aagatattta ttgaagaaca
    13681 caagatgtat cgttgggatg aaaagactat caaatctgat aatcctagcg ttatcaaaga
    13741 agatgaccat acatgcgaca caacacagta ttttgtgtta gacaatgcaa aattgctcgg
    13801 tttgcgtgtt ggtaacgttt agaggaggac gatcatgagc ctatttcaaa aagtaaaaga
    13861 cttttttagt cgagggaggt attacatgca gacatcaaat cttaatagta ttttggaaca
    13921 tccaaaaatt gcagtgactc aagaggagta tgaccggatt aagagaaatc tagtctacta
    13981 tcaatcaaaa tgggatgatg ttcagtacaa gaatacggat ggagatatta aatcccgtcc
    14041 aatgaatcac ttgccaattg caagaacagc atcgaagaag attgctagct tagtttacaa
    14101 tgaacaggca actatcacaa caaaaaacga aattttacag aaatttttgg atgacatgct
    14161 aactaacgac cgattcaata agaattttga gcggtatcta gaaagctgtt tggcacttgg
    14221 tggcctagct atgcgccctt atattgacgg ggataaggtc agagtggcat ttattcaagc
    14281 gcctgtgttc tttccactag aaagcaacac acaagatgtt tcaagtgctg caatccttac
    14341 taagactatc aaatctgagg ggcgtaagaa cgtttactat acccttgttg aatttcacga
    14401 atgggtaaca gcagacggac aagaaacagg tagcacaaac gataaaaagt attatcgtat
    14461 tacaaatgaa ctttataggt cagatgtgaa tgatgtgtta ggtcaacgtg tgaacttgag
    14521 tgaactagac aagtacaaaa atttagagcc tgtaacagtc tttgaaaacc tatcaagacc
    14581 tctatttact tatctaaaaa ctccaggtat gaataacaaa gacatcaaca gccctcttgg
    14641 tttgtctatc tttgataacg caaagacgac tattgacttc atcaatcgtt cttacgatga
    14701 atttatgtgg gaagtgagga tgggacaaag acgagttatt gtgcccgaac atctaacaca
    14761 aagacaatat caacgtccag atggaacaat agattttaga ccacggtttg atgttgagca
    14821 gaatgtttat atgcaaattg gcggctctag tatggatgcc gggggcatta cagaccttac
    14881 ctcaccaatt cgagcaaatg attatatttt ggcgatttca gagggattga aactctttga
    14941 aatgcagatt ggtgtatcaa gtggcatgtt tacattcgat ggtcaaggaa tgaaaaccgc
    15001 aacagaaatt gtcagcgaga actcagacac ttatcagatg cgaagtagta ttgtcgcact
    15061 tgttgaacaa tctatcaagg agctttgtgt ttcaatgtgt gagctcggta aggcggtagg
    15121 ggtttacagc ggagaaattc cagaacttga tgatatttca gttaatttgg atgatggtgt
    15181 atttactgat aggcatgcag aacttgatta ttgggctaaa atggtagccg caggattctc
    15241 aaccaaaaaa cgggcaattg gtaagacatt aaatatttct gatgttgagg cagaaaaaga
    15301 actcaatgct atcaatagtg agttgctacc tatgaatgat gccgaacttg ctatttatgg
    15361 tatgcatgac caaaacgagg aggaagcaga tgacaaaggt taaattcgga gttactagtg
    15421 ttgactactc agcaagcatt gaagatacgc caacaataaa attaggttta ataattagag
    15481 ggagcgggag actagatgcc tcttcagtta ttaaaaaact aatcaaggat gtttctgaac
    15541 tagaatacga attagaagaa taaactggtc aattggccaa ttttctttca agagagggct
    15601 tttgaatgaa aaaaaagaga aaacagctca cgtttaacga ccaacaattt cctttgcaaa
    15661 tgcaaggcgt tggggatatt tacgaaaaat tacagattga tatctttgac cgtatgataa
    15721 aacgcttaaa agagcgtggg tctattgatt taatgagaaa cccttatatc tggcagttag
    15781 agaaactaaa tgatatgcac atgctcaatg aacagaatct aaagcttatt tcagagcgta
    15841 caggaattgc tgaaagattg ttgcgtgatg taattgagaa tgaaggtttg aaagtctata
    15901 aggacactaa acagcaactt gaagaagatt tgaataaaat acctgaggga gagatttcaa
    15961 atggcgttac ggacagctta gaggcttatt cgaggcaagc agttagtgat ttaaacctta
    16021 tcaatacaac attgcctaag agcttgcaag tagcttataa atcgattgtg gaggagacag
    16081 tcgcacaggt agttgcagga actaaaacaa gcgatgttgc tttgcatgat accatcatga
    16141 aatggcagaa gaacgctttt acgggctttg tcgataaagg tgggaggcat tggaaagctg
    16201 atagctatgc gagggctatt atcaagagca caacatacaa agtttataac gaaatgcgta
    16261 ctagacctgc tgaggagtta ggagtagata ctttttacta ttcgatgaaa gcaatggcta
    16321 gaccagcttg tagtccgtta caagggcaga tagttacaaa aggggctggt agggagatag
    16381 atgggataac tatctattca ttattggatt atgggtatgg aacagcagca ggatgtttag
    16441 gaatccattg tggtcattat ctgacaccgt ttattgttgg agttcatgag ttaccgaact
    16501 taccagacta tctgaagaat ctaacaccag aacaagctga agaaaatgca cgcattgaag
    16561 caggtcaaag aggccttgag agacttatca agacacataa agagcggttg cattacgctc
    16621 ataccttgca agatgacaag atgatacaag ctgagcgttt gaaagttaga gggtatcaaa
    16681 ctaagatccg caacttgata aatcagcatg atttcttaac aagagattac agacgagaga
    16741 aattatatat ttcataaagg atttgtgttt cacaagtcct tttttgtgtt taaaaccgta
    16801 aaaaatccct atccatcaaa ggtatattga gagagtaaat aatattttgc tttaggtggg
    16861 agttatccac ctaaaaaaga actaggaggg tacaaatggc atttacaact gaagaactac
    16921 tcaatcttgg gttgacagaa gaacaggcta agtcagtctt tgctttgcga ggaaaagagc
    16981 tgaatgagga caaatcagcc ttagaaacta tcaaacaaga gcgagatagt ctcaaatcac
    17041 agttgcaaaa agcagaggag caagttgaac acttgaaatc acttgagaat atcagcgctg
    17101 aacaaaaaga tgcgattgat aaattgcaag ctgaatatga caagtataaa aacgaagctg
    17161 cagctgaact tgcacagaca aaaaaggtta gtgctatcag tctagctctg aaagatacaa
    17221 atgctttcaa tccagacaaa ttgatgaaat tcattgatgt tgatgctatc cagttagacg
    17281 acaacgggaa acctcagatt gatgaagtaa tcaacggttt aaaagaaagt gatccatatc
    17341 tgttcaaagc tgaagaaagt aagcctagcc ccaatatttt acctcaaggt aatccggcag
    17401 gagagggtac aagtgatgtt gatccgttcc aagcgattat tgacgggtat ggcaaataac
    17461 agaaaggaga ttacaaatgc caagtaatca aaacaacgca gtgcgccgct atgagaaaca
    17521 atatgcgggc attcttgaga cagtttttgg agtgcgggca gcattttcaa acgctctagc
    17581 acctattcag attttggatg gggtacaaga aaactctacg gctttctcag ttaaaacaaa
    17641 caacacacca gttgtaatcg gtgagtacaa aaccggtgaa aatgatggtg attttggtga
    17701 taactcaggg gctcagtcac gctttggtgg tgtgacagaa gttaaatatg aaaatacaga
    17761 tgtcaactat gactataccc ttacaatcca tgagggtctt gaccgttaca cagtaaacaa
    17821 tgatcttaac gctgctgttg ccgaccgctt gaagttgcaa tccgaggcac aaactcgaac
    17881 agtgaacaag cgaattggta aatacttgtc tgacaacgct actaagacgg aagcccttgc
    17941 tgattttaca gatgacaaag taaaagcttt attcaataag ttgtcggctt tttacacaaa
    18001 caacgaagtt acagcgccga ttactgttta cttgcgttct gaattttaca acgccatcgt
    18061 agatatggca tcagttacaa gcgccaaagg ggcaactatc tcccttgatg aaaacgggct
    18121 accaaaatat aagggcttta ccttggaaga aacgccagcg cagtactttg agacaggagt
    18181 tatcgctatc ttctcaccaa acggtattgt cattccgttt gttggtatct caacagcccg
    18241 tgtaattgag gctgaaaact ttgatggtgt gaaattgcaa gctgctgcta agggtggtac
    18301 ttacactctt gatgacaata agaaagcaat ttacaaagtt acaggaacta ttgtatagga
    18361 ggtagaacat ggcactttac aaagcaacaa aaaatctttt ctttgagcaa ctcaacatgg
    18421 atgtgattgt cgatgacatt attaaacttg atgaagatta tgctaaagaa gtcaacaaga
    18481 aactaaaaaa tgcttttcca gatgtgaaaa atgttttaga acttgttgac aaaaatggaa
    18541 cgcttgaacc agaagatgcc ccatctgtag atgatgcatc tcaggcaact gttgaagatt
    18601 aaataagggg tggcaacacc ctttattttt aagggaggtt acacatgact tatttgacac
    18661 aagaggagtt cgatgagtta ggttttgatg aagttacaga ctttgaaaaa ttggcaaaac
    18721 gggcaaagat agcgattgag ctatacacaa acggtattta tcagaaagac attgattttg
    18781 aaaaagaaat tgcctatcgc aaatctgctg taaagcttgc tatggcattc caaatagcct
    18841 atctcgatgc ctctggtatt atgtcagccg atgacaaaca gctagccaat agtgtctcta
    18901 ttggccgtac atcaatctct tatagcacct cacaaagcac attagcaggt cagcgattta
    18961 atttgtctat ggatgctgaa aatgctttga gacaagccgg ctttagccta gttgttggag
    19021 ttgcctatga tcgataagcg gttattaaaa gggattgaca agcgtttgtt aaaggatgtc
    19081 ctaaccataa aaaaagtagc tgataaaaac gattatgggg atgaagtata ttcagaaccg
    19141 ttgactatta aaaatgtacg ttttgataga tcagtggggg gatctggtaa tcgtaattca
    19201 aaaactggta caggtaattc aaaaactggt acaggaaatt caaaatcaag gcaaaaacaa
    19261 ggggttatat acctctatcc ctcgctatct tttgtgacag ttgataacag ttggatgggt
    19321 gcaaaagtaa acgatgggat aggagattat acaattaatg gatttcaaac taactattat
    19381 gatggtgaga tattcagtca agaaattgag gtgatctaat gagtatcgcc attaaagttg
    19441 acttgcagaa agctaaacag aaactttcga acgaatccat gacaagagga aagattgcag
    19501 tcgctagcaa aatcttgcta aacaatgagc aatatatccc cttgaggggt ggagagttga
    19561 gagcttctgg ccgaatcgtt ggacaaggtg atgctgttgt ctatggaaca gtttatgcta
    19621 gagcgcaatt ttacggggca aacggcattg tcacctttag gagatatacc actccaggta
    19681 caggaaaacg atgggatcaa gttgctacta gtaaacatgc tgaagaatgg gctagagctt
    19741 ttgtgaaagg aatgggactt tgatgcgaga gaatgacttt caaaatgtac ttttaaagca
    19801 tatcaagact ttaaatttac cagttgaacc acgctttgat tactttgagg atgacaaaga
    19861 tgatctggtt atcaatcaga taccaggcgg gaaagtggat agagagtata tggatggcac
    19921 acaagaagtt tctttgccgt ttgaaatcgc cgtaaaggca aaaaagaact cagtagccaa
    19981 tgacactatt tggttagtca cctcagaact agcaaagata gacttagttt taccaagtga
    20041 caataattct tatgaatata tgggaatgga agtcagcagg cctgccatga aaggcaagga
    20101 tgagcaaggc tattattatt acacaattga aattgtggcg aaaatcgtaa tagagaggaa
    20161 caaacaatga caagacaaaa aaacgcccta cgtggccatt ttgtagctcc atacaatgga
    20221 ggaactgaac catcaacaga agatacatgg ttggaacttg ctaaatggat ctcagacgta
    20281 tcagatgata cagacgagaa aacagatgat caagcatact atgacggtga tggagttgaa
    20341 gaaacaaccg tggtcagcgt aaaaggtgct tatacctttg agggtactta cgatccagac
    20401 gataaagcac aggctcttat tgctgggatg aagtacaaga caggggatga ccgtaagcta
    20461 tggcacaagg ttgtttcttc tgacaggaag aaacaatggg tgggagctgc aactgcaaca
    20521 gaaatcaaag caggttctgg cgctgcctct gactatgagg cgtttggatg taagctttct
    20581 tacaactcaa cgccaaaaga gactggtatt gggtaatagc ttttgataag ggcgggcatt
    20641 gagccttgcc ctttttaaca acaggaaaag gagtaaagac atgacagata ttcagattga
    20701 actaaaacgt acaggatttc cagtaaaaat cggagaagta gagctatggt ttgatacaag
    20761 tcaagagagc ttaatgcgct tttatgacat ggaagaagaa ctaaaacgtc gccttgtcca
    20821 atatgaatta gatgtggtat ctgcaaatat caataacaaa attgagcgtg atggagtaac
    20881 taaagaagta gttgctgggg ctattgaatt ggagaagaaa cagcttgaga ttcaatatga
    20941 tcttattttt ggcgacggta catttgacaa gttatattct atatatccag attataacgc
    21001 cctaaataac gctctagaac agaccgcaat catgttgcat gacaagttgg aagaagttgc
    21061 tgagcaacac aaaacggtgg tgaaagagcg tgctagtcac tatttaaaca agggaaaagt
    21121 cactccaatc aagaacaaca agaaacaaaa aaagaacaaa aagaaatagc aggtaaaaaa
    21181 tatgtctatg aaattaaatg atgccttaat cacaaatttt tctattgctg ataaagagta
    21241 cgacatagac ctgtctttta ataaagttct agatgtcttt gaaatcctaa aagaggatga
    21301 aatgacgcgt ctagaacaag ctcagttgat tgtccatttg ctaactggcc aagaattata
    21361 cgacatcaaa gaggttgtag attgttggat ttacataaaa gaacactttc tagggatcga
    21421 aaaagaaact gttcagtatg atttgctagg caatcccatg ccaaaggcaa aaggtgaaga
    21481 agaacaagaa aaattgattg attttgaaca agatgcagag tacatttatg ctagtttttt
    21541 acaagcctac ggcatcaatc ttttgaaagt tcaaaatgag ttgacatgga cagaatttaa
    21601 agcacttttg aacgctttgc cagataacac aatcatgcaa cagattatag aaatccgagc
    21661 atggaaacca gaatatggtg gggataaaaa taaaatgcgc aaattacaag ctaaatatag
    21721 tttaggaaag gagggagaag ataatgtctg atggaaaagt gactatcgtt gtcgatgtgg
    21781 atggtaataa agtcaaggtt ctaaacgatg agttagataa aacggcacag aaaggtgata
    21841 gagggagcag ttccctaaag aaatttgcgg taggcagtgc agttttccaa cttgccgcta
    21901 aaggtgctga acttttggga gaggctttag gaggcgctat tcagcgtttt gacacgttag
    21961 aaagttatcc aagagtgatg caagctatgg ggcatagtac agaagatgtc acgcgctcaa
    22021 ctaagaaact agcggcaggt attgagggtt tgcctacgac tttaaatgaa gtggtaggca
    22081 cagctcaacg ccttacctcg attactggcg atataaacaa atcaacagat ttaacacttg
    22141 ctcttaataa tgcctttctt gcttctggat cttctagtgc tgatgcaagc cgtggtttac
    22201 aacagttcag tcagatgtta tcagctggta aggttgacat gcaaagttgg aaaacgttac
    22261 aggaaaccat gccttatgct ttgcaaaaga ctgctgaatc attcggtttt gctggccaat
    22321 ctgctcagaa tgatttctat tctgcattaa aagaggggcg tatcactttc aaccaatttt
    22381 caagcaaatt ggttgaattg aatggtggcg ttggtggttt tgcagaactt gctaaaacta
    22441 acagtaaagg gatccagaca tcttttggga acttaaagaa tgcggttgtt aaaggtgtag
    22501 ctaatactat caaggctctt gacgatttaa caaaggcagc aacaggtaag acgattgctg
    22561 agaacttcga tgcattgaaa gtaatcatca atgcggcttt tggtgttatt gtcaacgtaa
    22621 ttaaagctag cacacctgtt tttcagactt tgtttagtat tttgggtact ggagcttctg
    22681 taatctcatt tttgacaccg gctattatcg gtttagttgc tgctttggta actatgcgtg
    22741 ccatcaatca agcggtaaaa acgactaagg acttgataag cgcgtggaaa acattcaaaa
    22801 caacagccac aggagcgatt cagatcatca atctaatgac agctgcccaa gctacttgtg
    22861 gctcagtaac aaaggctcaa ctggttgcta acttggccaa taacggagct ttgacagcat
    22921 ccaatttgct ttatggggtt ctaactggct ctatcagctt acagactgct gctactattg
    22981 ctgcgactgc tgcaactacc gcatttaaag cagcgctgac agctttaacc ggcccgattg
    23041 gtttggttgt tgctgggatt ggtttggttg tgggagtatg tgtgactttg tggcaatggc
    23101 taactgccga gagtgaggag accaaacgcc tcaaatcaga acaagaggag ttagtcaaga
    23161 gtacggatca attaacggat tctgttaaac aaagcgcaaa agaacgtcaa aaaaatcttg
    23221 agtctgtaaa aggtaataca gaatcttacc aaaaattggc tgacgaaatt gtccagttat
    23281 cacaaaagac aaataagaca gcagcagaca agaaaaatct taagaaaaag attgatgctt
    23341 tgaacgcctc agttagcggt ttaaatctag cctatgataa gaactctgat tctttgtctc
    23401 ataacagtga ccaaatcaaa gctcgtatat cagcgatgga ggcagaatca acatgggaga
    23461 catcccagaa gaacctgctt gatatcgaac aaaagcgtgc tgaaattggc gaacagctaa
    23521 agaagatagc tgaacaacgc aaaaaatgga atgaagaatc caatgttagc gatagtgtcc
    23581 gtaaagaaag actgcaagaa ctcaacgaca aggaaactga gctaaaaaat actcagacag
    23641 aattgcaaac tgagtacgaa aaaacgtctc aagttcaaca ggcggcatct gaagcgatgg
    23701 ctgctgctgc cgaaaatggt tcaaatagac aagttgtagc atacgaaaat atgtctaaat
    23761 ctcaacaaaa agcaatagac gatatgcgta ctaagtacaa tgaattactt gagacaacta
    23821 cgaacatgtt tgaacaaatc aagtataagt ctgctattag tgtcgatgaa atgattgcca
    23881 acctccaaaa aaaccaagag gcggttaata attgggcaac aaacctcaat acattggccg
    23941 aacgtggggt aaacgagggg attttagcta aattacaagc gatggggcct caaggtgggt
    24001 tgtacgttca agaactcgtt aatgcatcag acgaaaaatt ggcaacattg aacgaagtct
    24061 ttactcaagg tggtgagtca gctatgaatg gcttaactgc tggtatggat acgggtgctt
    24121 tgggtatcac agacaaaatc aagggtattg tacaaagtca agtttcaagc ttacaagagg
    24181 aaattgcagc tgctgacttt tctagtttgg gacaagaaat ccccaacggg gtcagtcaag
    24241 ggatagaaca aggagtttct actgccggag aatcttctaa aaacatggct aatgatataa
    24301 aagaatcctt tacgagcgaa atggatatta attccccatc tcgtgttttc aatgagtatg
    24361 gtggttttat cactactggt ttagctgagg gggtagataa aggtaccaat caacctgtat
    24421 catctgttac taatttagcc aatcaaatta agaaaccatt tgatagtctg cagagtgatt
    24481 tcacgtacat tggtgaaatg gcgatgtctg gtcttaatgc agggctttgg agtggctctg
    24541 gttctgttat ggcaacagct aattcaattg ctgaaagggt aaaagcgacc atcaagagcg
    24601 cactagatat tcactcgcca tctagagcaa tgcgtgatga agtcggacgt ttcattcctc
    24661 aaggtatcgc tgttggtatt gaagcagatg caggggttgt tgaaaaatca atgttgcgat
    24721 taaaagaaag catgatgatt gatactagac cagaaattgc acttggctta aacaagaaac
    24781 taggtgctca agtgactgtt aaacaaagta gtaagcagac aatagctgaa aaaatcaaag
    24841 ttactatgga caagtctagc gaactactcg aaaaagccct ggatgtagct gagacggccg
    24901 ttagacgacc aaatgaaatg tacttaaacg atggtacttt agtcgccaga acaggcgata
    24961 aatttgctaa atatcaatcg gaacaactaa gacgagataa taggatgaaa ggggtattgt
    25021 catgacaaag ataatgactt tcaacggagt tgatatgtct aaattctttc gtataacaga
    25081 tattatccgc cctatcggga acaagaggag cgtatcaact gataacgctc ccttattggg
    25141 cgtgaatatc caacaggtta agattggaga aaaagagcat atcataaaat ttgacatcaa
    25201 aaccacaaat gcaattgaaa tggaacaatt aaagcatgat ttggcaggca ttctaaacgt
    25261 tttagagcca gtaaagatta cttatggcga tgagccagac aaatactata tggggttgcc
    25321 ggtagatgag attactccag aaaatttgac aagatggttc cagcgctcag agttaaaaat
    25381 aataattcct gatggcgtgg ctcacagcac gactttaaaa aattttgata tcgatacaaa
    25441 tgaaacaagc gcaccggata ggatagtatt taatttaaca aatacaggaa cagagccagc
    25501 ttatccaatt attagaatta aacacaactc agagaatgga tatattggag ttgttaacaa
    25561 cagagcggcg tttgagttag gaaatcgtga agaggctgat actgaaaaat acagagactc
    25621 tgaaacattg atagattata gagggactaa tattctaaaa ggatttcaaa atggcactaa
    25681 aggagtagct gtaacaaatg ataataagga gcgtcttgtt ggcactttga gtacaacaag
    25741 tatgtggggg cgtaatcata tcgaattatc aaaccgtggt acagttgaaa aaaatcgaaa
    25801 taatgcacaa agtttgacat gggctattcc tgttgatagt agtggagaag ttggttcatt
    25861 gaatgactat ctgctttgga gacaagtttt tatggcagca gtcgctaatc aatatggttt
    25921 cataaaggtt actgtatcgg atacagacgg caatttcttg tatggggtgg aaacttacaa
    25981 acgctatcag acacttgatt gtgagtatag ttttttcacc actgacggca aaggtggata
    26041 caagtttatc aaatggtggt attttactgg gacaggggct caagtaggca aacttgatcc
    26101 atttagcgcg gaaaagggct ggtcagagtt aaaaagaaac gatgatagag ttcaagtgtt
    26161 ttttgatggc tctcattatg actttattat tccggagata aaagacaaaa aatcagcaaa
    26221 aatccatatc acgcttggag cactcagaga ctggcctctt atatcacata tgtatgttga
    26281 tgagttcatg tatagaaaag actttgtgac aaagagtaga gatattccta atcgctatcc
    26341 aataggttca aatgttgtaa tcaacagtga ggacgatagt gtgtatattg acgggatatc
    26401 taaagtaagc gaagttgtag acggttcaca ttggccagca attcctccag gaaaatctca
    26461 actagagttg tatttttcac gttttgttaa gaaaaaacca actgtaacaa tcgaatttga
    26521 agaaaggtgg atataagatg cttttgacaa tccatgatgc aaatttacaa aaggtagcat
    26581 ttattgataa cgaaaaacaa ggtacgttaa attattacga tgatacttgg acaagaagtc
    26641 ttgcaacagg ttcgtcaacg tttgagttta cggtatttaa aaaggctgta aagtctgatt
    26701 tacctcttgc taaagcctat catcatttga atgagcatgc atttgtctca tttaagtaca
    26761 agggtaaaag ctttgtgttt aatatcatta ttgttgaaga aaatgagcag acaatcaaat
    26821 gttattgtga aaatctcaat cttgagttaa tcaatgagct tgcgaaccct tataaatcta
    26881 acaaagcgat gactttcaaa gagtattgtg aggcgatgga tcttttaaat tatactcacc
    26941 tttctattgg tatcaatgaa atatcagatt ataagcgtac tctggaatgg gaggggcaag
    27001 aaaccaaact agcccgtcta ttaagcctag ccaaacgatt tgatgctgag attgaatttg
    27061 atacacagtt aaatgctgat agcactatca aaaagtttag tgttaatgtt tatcatgaaa
    27121 acgatgacaa ccatcaaggg gtgggacgtg taagaaatga tgtcattgtt aaatacggaa
    27181 aaaacatcca ctctattaca agaaaagtgg ataagactgg tattttcaat acaatcagac
    27241 cgactggtaa aatgccaacg gttgaagaag aaccgagcgg agataagggc tccaaaagcg
    27301 aaactgtaaa aaatgcagat ggttcaacga cgaaaaccac aatctctaca gcctcagatg
    27361 ggactaagag caaaactatt gtccacacta aagttacaaa gttagcggac aagacacgga
    27421 tcacaacgac cacaacgact cgttctgatg gttccataga acaaactgtt acaaccagca
    27481 aaaaaggcgg agcatcaacg tctgaaacaa aagtcttgaa aaaaccaaat ccaaaagaaa
    27541 aaacaaatac aactgaggat gttttgacga ttgagggatt ggatgaatgg gaagtaaaga
    27601 acgagaaagg gatagttgaa ttttatcaaa gagggcaagc actgtatgcg cctatttcaa
    27661 tgcaactata tccctcaacc tttactcatt caacagggga gcttgaccag tggacaagaa
    27721 aagattttca ttttgaaaca gatgagccaa acgagttaag acgtttaggt tatctcaaat
    27781 tgaaaaagta ttgttatcca gctatcactt atgaagttga tggctttgtc gatgctgata
    27841 ttggagatac tgttaaagtc catgatgacg gttttgcccc tctattgatg attcaagcac
    27901 gggttactga tcaaaaaatc agtttcacaa atccagtgag aaataagaca atatttgaca
    27961 atttcaaggc acttgaaaac aaactatcag ctgatatcca gtcagccttt gagagattgt
    28021 ttgaagctgc taaaccatat actatcaaat tgtcaacgga caatggtgtt atctttaaaa
    28081 atcagatcgg ccagagtcta gtaaccccaa ccttatacaa gggaggaaaa ccagtcgttg
    28141 ttggtgttac ttggcgatgg gcacttgatg gagaagtaac aacagggatg acttacttag
    28201 ttagaggctc aaatgtaact gatacagtta ctctgacagt tgcagcttac attggaaata
    28261 aagaggttgc tgttgatgag atatcgcttg ttaatgttgc tgatggaaaa cttggtacac
    28321 ctggaactcc agggcgagat ggccgtactc cttatgtcca tacagcatgg gctaataatg
    28381 caacaggaac agatggattt agtcttgata gctcaatcaa taaactctat attggtattt
    28441 atacagactt tgaaccaaac gatagcacag accctaaaaa atacaagtgg gctaaagtaa
    28501 aaggagacaa gggagaaaaa ggagataaag gagaaccggg acaacgtggt ttagatggct
    28561 tgcaaggtgc acgaggtgaa caaggattac ctggtcgcaa tggtgcagat ggccgtactc
    28621 aatacactca catagcttac agcaatagcg ctgatggaac taaggatttt tctgtaagcg
    28681 cctctgatag agcttatatc ggtatgtatg ttgattttaa tagtgctgat agtaatactc
    28741 catctgatta caattggaca cttgtaaaag gagctgatgg cgcaaacggc gtggcaggta
    28801 aggctggtac agatggtagg acaccatact tacacatagc ttacgccaca tcaaataatg
    28861 gatcacaagg tttttcaact actgacagta caaataaaac gtatatcgga acatacacag
    28921 attacactca ggcagatagc acagattaca gagtgtataa gtggacgttg ataaaagggg
    28981 cagatggtac tggtatttct aatgtaacta attattattt agctactaca gtctcaacag
    29041 gtatcacaag aacaagcgca gggtggacaa ctacgccaca gcctatcaca tcagacaagc
    29101 gttatttatg gaattatcga gttgagctat acacaaacgg tacaagtaag acaacagagc
    29161 ctactgttat tggtgtgcac gg
//
LOCUS       DAVLGK010000028        28137 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLGK010000028 DAVLGK010000000
VERSION     DAVLGK010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28137
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.028"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            1..984
                     /locus_tag="VXE01_001341"
                     /pseudo
     CDS             1..984
                     /locus_tag="VXE01_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1113..1316)
                     /locus_tag="VXE01_001342"
     CDS             complement(1113..1316)
                     /locus_tag="VXE01_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0750241.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1309..2391)
                     /locus_tag="VXE01_001343"
     CDS             complement(1309..2391)
                     /locus_tag="VXE01_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0750242.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2517..3299)
                     /locus_tag="VXE01_001344"
     CDS             complement(2517..3299)
                     /locus_tag="VXE01_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV0750243.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILNQEIAEEYSDVKSKADFS"
     gene            complement(3299..4642)
                     /locus_tag="VXE01_001345"
     CDS             complement(3299..4642)
                     /locus_tag="VXE01_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV0750244.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLAIRQIVRKEMN"
     gene            complement(4741..6057)
                     /locus_tag="VXE01_001346"
     CDS             complement(4741..6057)
                     /locus_tag="VXE01_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV0750245.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6251..7477
                     /locus_tag="VXE01_001347"
     CDS             6251..7477
                     /locus_tag="VXE01_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV0750246.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILAGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7676..9250
                     /locus_tag="VXE01_001348"
     CDS             7676..9250
                     /locus_tag="VXE01_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0750247.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVSPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            9514..10302
                     /gene="codY"
                     /locus_tag="VXE01_001349"
     CDS             9514..10302
                     /gene="codY"
                     /locus_tag="VXE01_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV0750248.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10302..10877
                     /locus_tag="VXE01_001350"
     CDS             10302..10877
                     /locus_tag="VXE01_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0750249.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10959..11044
                     /locus_tag="VXE01_001351"
     tRNA            10959..11044
                     /locus_tag="VXE01_001351"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10993..10995,aa:Leu,seq:aag)
     gene            11327..12457
                     /gene="ugpC"
                     /locus_tag="VXE01_001352"
     CDS             11327..12457
                     /gene="ugpC"
                     /locus_tag="VXE01_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV0750250.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(12604..12750)
                     /locus_tag="VXE01_001353"
     CDS             complement(12604..12750)
                     /locus_tag="VXE01_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750251.1"
                     /translation="MEIKEQTRKLAVSCSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEY"
     gene            12958..13716
                     /locus_tag="VXE01_001354"
     CDS             12958..13716
                     /locus_tag="VXE01_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0750252.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13803..14315
                     /locus_tag="VXE01_001355"
     CDS             13803..14315
                     /locus_tag="VXE01_001355"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV0750253.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            14497..15441
                     /locus_tag="VXE01_001356"
     CDS             14497..15441
                     /locus_tag="VXE01_001356"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV0750254.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYRYL"
     gene            15450..16127
                     /locus_tag="VXE01_001357"
     CDS             15450..16127
                     /locus_tag="VXE01_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV0750255.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEISPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            16225..16983
                     /locus_tag="VXE01_001358"
     CDS             16225..16983
                     /locus_tag="VXE01_001358"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV0750256.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            17021..18525
                     /gene="lytC"
                     /locus_tag="VXE01_001359"
                     /pseudo
     CDS             17021..18525
                     /gene="lytC"
                     /locus_tag="VXE01_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            19031..19549
                     /locus_tag="VXE01_001360"
     CDS             19031..19549
                     /locus_tag="VXE01_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV0750257.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            19679..20185
                     /locus_tag="VXE01_001361"
     CDS             19679..20185
                     /locus_tag="VXE01_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV0750258.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAEFQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            20185..20355
                     /locus_tag="VXE01_001362"
     CDS             20185..20355
                     /locus_tag="VXE01_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750259.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAVYMTLF"
     gene            20387..21619
                     /gene="clpX"
                     /locus_tag="VXE01_001363"
     CDS             20387..21619
                     /gene="clpX"
                     /locus_tag="VXE01_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV0750260.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21628..22215
                     /locus_tag="VXE01_001364"
     CDS             21628..22215
                     /locus_tag="VXE01_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV0750261.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            22226..22606
                     /locus_tag="VXE01_001365"
     CDS             22226..22606
                     /locus_tag="VXE01_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV0750262.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22658..23548
                     /gene="rapZ"
                     /locus_tag="VXE01_001366"
     CDS             22658..23548
                     /gene="rapZ"
                     /locus_tag="VXE01_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV0750263.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKCLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            23545..24522
                     /locus_tag="VXE01_001367"
     CDS             23545..24522
                     /locus_tag="VXE01_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV0750264.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIVDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            24519..25430
                     /gene="whiA"
                     /locus_tag="VXE01_001368"
     CDS             24519..25430
                     /gene="whiA"
                     /locus_tag="VXE01_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV0750265.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(25518..26645)
                     /locus_tag="VXE01_001369"
     CDS             complement(25518..26645)
                     /locus_tag="VXE01_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0750266.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(26762..27277)
                     /locus_tag="VXE01_001370"
     CDS             complement(26762..27277)
                     /locus_tag="VXE01_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750267.1"
                     /translation="MKRIFSISSVLLCALVISTACTNQTQKSSSEPTTQASSSDDISV
                     EEYFDKLLTKVDKVTKDNYKSDDYKIYDYKTVLREPEKFFSLKMRIDNLEIVQIFKEG
                     KYTKMLVTQPSGDFYMLFMETKRIEKRFLEKDHLTVNGRYLLSYEYTTNSNKEKSVPL
                     IYVDAYLLLKN"
     gene            complement(27295..27675)
                     /locus_tag="VXE01_001371"
     CDS             complement(27295..27675)
                     /locus_tag="VXE01_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV0750268.1"
                     /translation="MTEKEFSQNLGIDIEIFEDGLFPDEAFYIPALKTMFLSDAISDE
                     KRVQVALHEIGHRNHAPDTYQLFREKCELEANRNMIHHLMKAELGIAEDATTFNYLVF
                     MEKYNLKTIADEIMVKEEYLALLN"
     gene            complement(27697..28059)
                     /locus_tag="VXE01_001372"
     CDS             complement(27697..28059)
                     /locus_tag="VXE01_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0750269.1"
                     /translation="MFETFEKIKSLAKKQGISLNTLEDRVGLGKNYIYSLKNKKTPSA
                     EHISKIADYFNVSTDYLLGRTDNPTIANKKEQFFFEGKEVDVEELASTAMRFNGKPLT
                     EEDKKAIQNIIEIYLRKQ"
BASE COUNT         8416 a         5129 c         6170 g         8422 t
ORIGIN      
        1 cgtaagccaa aaacgagacc tgaagagagg acagaattag aacgtcttca atcagaaaat
       61 gagtacctga gagcggagaa tgccatccta aaaaagttaa gagaactccg attgaaggag
      121 gaaaaagaga aagaagaaag acagaaattg ttcaagaatt aatgactgag ttttcgttag
      181 atcttcttct aaaagccatt aaactagctc gttggaccta ctactatcac ttgaaacagc
      241 tagataaacc agataaggac caagagctta aagctgaaat tcaatccatc tttatcgaac
      301 acaagggaaa ttatgcttat cgtcgaattt atttagaact aagaaatcgt ggttatctgg
      361 taaatcataa aagagttcaa gacttgatga aagtactcaa tttacaagct aaaatgtgac
      421 agaaacgaaa ataaaggaga cgttggtaag aaggcagaga atctcattca aggccaattt
      481 gaaggctcta aaacaatgga aaagtgctac acagatgtga cagaatttgc cattccagca
      541 agtactcaaa agctttactt atcaccagtt ttagatggct ttaatagcga aattatcgcc
      601 tataatcttt caacttcacc caacttagaa caagtacaaa caatgttgga acaggccttt
      661 acagagaaat actatgagaa tacgattctc catagtgacc aaggctggca ataccaacac
      721 gattcttatc atcagtttct tgagggtaag ggaattcaag catccatgtc acgcaaggga
      781 aacagccaag acaacggtat gatggagtcc ttctttggga ttctgaaatc ggaaatgttt
      841 tatggctatg agaaaacatt taaatcactt aatcaattgg aacaagctat tgtagactat
      901 attgattact acaacaataa acgaattaag gtaaaactaa aaggacttag ccttgtgcaa
      961 tacagaacta aatccttcgg ataaattaat tgtctaactt ttggggggca gtacatattc
     1021 aacacctgat actatgcgtt ttattgtggg aagattttcc tcattttcta gtgaaattga
     1081 actttttcta acatcttttg atagatgact tcttaatcaa ttatcatttc cattgttgtt
     1141 tcttggggtt tcatcccttg tctttgataa aagcggagag caccctcgtt atcattccag
     1201 acacttaggg ttagattatt gcagccaatt tctttagcat aatagcagaa aaatgacaat
     1261 aaaatagccc ctagatattt tgaaaggaaa gcataggggc tatatagttt aatcaaaata
     1321 aagcaaatct ttgctggtgc ttgtaaagag gtcgaagcca tccttggtaa caacaccgca
     1381 gtcttcaata cgaacaccga ctttaccagg gatatagata cctggttcaa cagagaagca
     1441 catgccttct tcgatgacca tgtcgtttcc ttccatgata gatgggaatt catggacatc
     1501 cataccgata ccatgcccga gacggtggtt gaagtactca ccataaccag ctttttcgat
     1561 gacctcacgg gcagcgcggt ccacttcatg agcagtcaca cctggcttga taaagtcaag
     1621 agcagcttgt tgggcttcaa gagtcaagtt gtaaatatct ttcttgaatt ggtctggttt
     1681 gccgacagcg actgtacgag tcatatctga cgcatagcca ttgaccagaa cacccaggtc
     1741 aaagaggaga agagcatcat tttcaacctt attagctgct ggaatgccgt gtggattcgc
     1801 agcattatca ccagtcaaga ccatggtatc aaagctcatt tcgtaacctt cacgtttcat
     1861 ggcaaagtca atttgtgcga tgatatctgt ctcagtctta tcaagagaaa tattgtcaaa
     1921 accaacatga acagccttgt cagcataaag acctgcaacc atcatttttt gcacttcatc
     1981 agctgatttg atgaggcgca tgcgttggat acgaggagtg aggttgtcaa actcagcagt
     2041 ctcaaaaact gttttcaaac catggtattt ggtcaagatg agattgtcaa actcaacagc
     2101 gacacgtttg aagtcaagtt gtggaagagc atgtttgatt ttttgccatg gattttcaga
     2161 atcgacatag cccactactg ggaaggaaac ggtgctactt gcacgttcta cttcaagagc
     2221 tgggacaaag aggagaggtt cctgatccgc taggacaaag aggaacattt ggcgttcatg
     2281 gggatcactg taaaaaccag tgaggtaatt gattgtgacg gggtcagata cgacagcgac
     2341 gtctagtttt tctgattcaa gatatgttag gatttgttgt aatttagaca tatgctacct
     2401 tctttctacc cctctatttt ggcaaaaaat gagagaaaat gcaagggaga agggtaaaag
     2461 aaaagacaaa aaactccgac aagataacgg agttctttga tatcattttc ctttgtttaa
     2521 gaaaagtcag ccttgctttt gacgtcactg tactcttcag cgatttcttg gttgaggata
     2581 tcctcatagg cagggagttg gatatcctga ccatatttct tcttgagggc agtagtaact
     2641 aggcgataag ccagattggc attacgagag aggataggcc cgtggaagta ggaaccaaag
     2701 acattcttat aatgaacccc ttcaccgacc ttttcttcgt tgtttccatt tccatagaca
     2761 acctgtccca gcggtttttg gtcatcagag aggaaggtac ggccttggtg attttcaaat
     2821 ccatagtagg tttcatcgaa atcttcattg tgaatcttga tgtcaccgat aaaacggtta
     2881 ttggtctggt tgagcgtgta gtgtcccatg acccctagcc cttcgatacg ttttcctgaa
     2941 gcttcaacat aatattgacc caatagttgg aaaccaccgc agatagccag aactacaccg
     3001 tcgttttgga tgtagttgtc aatgctctct tttttagcag gtaggtcgtc tgcaatgata
     3061 ctttgttcaa agtcttgacc accaccgaaa aaggcgatgt cgtagtgatt ttcatcaaag
     3121 tcatcatgga gagaaacgat gtcaacggtc acatgggctc ccagtttttc agccacatac
     3181 ttgagcatga ggatgtttcc attgtccccg taggtattca tgagatttcc gtagaggtgg
     3241 gcaatgttga gctgataggg gtaattacca tcttttgagg aaagtgaagt ataaaccatt
     3301 agttcatctc ctttctaaca atctgacgaa tagccagcag ttcacgaaat tccagcatgg
     3361 cagtataagt tgccagaata taggcatgct tgcagtcttg attctcaatg gtcttgagaa
     3421 cttgctccag attactcgtt tcagtgattt tctcagctgg atagccagtc actcggaggc
     3481 gacgagcgat ttcagaatga cgaacaccgc cagcgttgat ttcaggaatg tccatgtcag
     3541 tgatttgctc aaagtctgca tcccagatcc agctagtgtc aattccatct gcatagttgg
     3601 cattaaggag gacagatagg ctaaatggat aaggtgctag tttgatcatt tcgatagctt
     3661 gggttgcacc gactggattt ttaatcaaga caagggtaca ttccttgtca ccgatatgaa
     3721 aggtttcttg gcgtccaaag acagcacggc tcttgtcaaa tccctgtttg atgagttgcg
     3781 aatcggcacc taggaaacgg gcgatggcca cagcagctag ggcgttatat atattataga
     3841 gcccgccgat ttggataccg tattcttggc cgtctatgac aaagcgagag cgattgttgg
     3901 tcaactcaac caattttgtc aaacgatagt cgagatcagg acgtttacat ccacaacctt
     3961 cacagatata ggcacccaag tttgcatagg tattatgctc atatttgagg atgccttggc
     4021 agtcaggaca gagaatccct tcggtattgt agtgagccag ttgggctggt cctttttcca
     4081 agtcaaaacc aaaatactct atagggtttg gaatagttgg cttgtagaaa agtggactgt
     4141 ctccgttaag gagaacagta gcagttggaa ctttccgaat ggcatccaat atcatgttat
     4201 aggtagtata gatttcaccg aaacggtcca tctggtcacg gaagatatta gtaatgacaa
     4261 aaagactagg ctggatatag tcacagatac gagatagact ggcttcgtca atttcgagga
     4321 cggcaatatt ttttccagtt ttagaagatt tggctgttag gaaggttgtt gcaatccctg
     4381 taatcatgtt ggcaccgctt gggttggtta gaacttgacc ataaacctct tttaaaatgc
     4441 cgacagtgag ggcagttgtc agggtttttc catttgttcc agtgacaacg acaatctcgt
     4501 agttcttagc taggttttgt aaaatatctt tatcaaattg aagggcgact ttacctggga
     4561 gcgtacttcc acgtccaaga cggcttaaaa cgaagtggga agaacgccca gcaagaaggc
     4621 ccaaagtagt ttttaagttc atgtttctat tatatcacaa aagagggaaa agacagattt
     4681 ggtgtttcgt agaagtaaaa acagcccaaa gagggctgtc agttaagatg agatttcaac
     4741 ttaaatcgca aacaagtcat tcaagttctc agccaaggtt gggtgagtga agatttgttt
     4801 tgtgaagtaa gtgtaaggaa tcttgttgtc catagcaaca gtaatgatgt tgatgatttc
     4861 ttgagaacct tctgagaaga tgcttgcacc aagaatttct tttgtttcag tattaacaac
     4921 agctttgaaa gctccgcgaa ggtctccatt tacgtgacca cgaggcatgg ctgcaacagg
     4981 gatttctttc actgcgtatg gaagtttcaa atcagctgct tggctttcag tcaaaccaac
     5041 ttgtgaaagt gcaggtgtga tgaacatagt atttggcaca ttgagacggt cctcaagtgt
     5101 gtagctgcca tctccagcaa ggtagctgta aacaacacgg aagtcatcaa gtgaaatgta
     5161 agtaaattga agaccaccgt tgacatctcc aactgcaaag acaccaggaa cgtttgtttg
     5221 acagtgttta tctactttaa tagcgccacg ttcagttagt tcaatatctg tattttcaag
     5281 ttgaagtggt tctacatttg gtttgcgtcc agttgcgtag agaagggcgt cgaaacggta
     5341 agtttcgtct tcagttacga caagcacttg gtcaccgtcg tttttaattt cagtagtatg
     5401 gatattttga agcaattcaa taccgtcttc ttccatgtat tgtttagcaa gagctgcgat
     5461 ggaaggttct gcacgaggta ggaatgtatc caaggcatct aggactgtga ccttgcttcc
     5521 aagtttgttg taaaggccgg caaattcaag accgatattt ccgccaccaa ggactccaag
     5581 tttttcaggc aatttatcca agctttggat acctgttgag tcaaagacgt ttttgcttgt
     5641 agcaagtcca gggattggca agacgtttga aacagcacca gtgttgatga cgatagtttc
     5701 agcagtcaat tcttgttttt catcaccagc ttggatttcg atgactttat ttgaaaggaa
     5761 gtgagcttca gcatcaaaga tatcgacgcc agtaccagca acagtcgtat agtttttacc
     5821 gttgaggcga ccagtgatcg tgtttttggt agcaatgact tcttcaaaag acaagtcttt
     5881 ctcagcagca accagcaaag ttttagttgg gatacaaccg atgttgatac aagttccacc
     5941 gtacatagct ttgctacgtt caacgagggc aacttttttg ccagctgaag ccaatttacc
     6001 agctagtgtt ttaccagctt taccaaatcc gataacgatt aaatcataag ttaacattta
     6061 gaattcctcc tattcgcatt tcattctagc acaagaaaaa aacttttgca caattctgct
     6121 acgaaaaaga cagaaaaaga taaaaacgct ttccagacaa aaaactagta attttttaac
     6181 aagcttgata aactaaaatc ctatctattt ttatataaga tagaataaat gttcgaaaat
     6241 aggaggtttt atgaaatcga atcgttatat tattgccttt gctggggtca ttttacactt
     6301 aatgctgggt tcgacttatg cctggagtgt ttatcgtaac cctattattg aaaaaacggg
     6361 atgggatcag gcttctgttg ccttcgcctt tagtctagca atcttttgtt tgggcttatc
     6421 ggctgcattt atggggcgtt tggtagaaaa atttggtccg aaagtcatgg gaagtctatc
     6481 tgcttttcta tacgcaggtg gaaatatctt agcaggattt gcaatagacc gtcaggagct
     6541 gtggttgttg tatctcgctt atggcatttt aggtgggctt ggtttgggag caggctatat
     6601 tacccctgtg tcgacgatta taaaatggtt tcctgataaa cgtggtctcg caacaggttt
     6661 agcgattatg gggtttggtt ttgcttcttt attgactagt cccatagcgc aacacctcat
     6721 cgcaggggta gggattgtag aaacttttta tattttagga gcaagttact ttattatcat
     6781 gctcctagct tcacaattca ttaagcgtcc aaatgagcaa gagcttgcaa ttttatcttc
     6841 ttcagggaaa gaaaaaacag cctctttgac gcaaggaatg gctgcaaatc aggctctaaa
     6901 aagcaatcgg ttttatatgc tttggattat tttctttatc aacatagctt gtggtttagg
     6961 cttaatttca gcggcatcgc caatggcaca ggagatggct ggcttgtcta caagtcatgc
     7021 agcagtaatg gtgggtgttt tggggatttt caatggattt ggtcgcttgc tctgggcgag
     7081 tttgtctgac tatatcggtc gccctctaac ctttagtata ttactgcttg tcaatctttt
     7141 cttttctctc tcactttggc tctttacaga ttccgtttta tttgtagttg ctatgtctat
     7201 tttgatgact tgctatggag ctggtttttc tttgattcca gcttatctca gtgatatttt
     7261 tggaaccaag gaattggccg ctctgcatgg ttatatttta acagcttggg caatggctgg
     7321 tttagcggga cctattttat tagcagagac ttataaaatg gctcattcgt acacacaaac
     7381 cttgttcgtt tttctcattt tatacagtat cgccttggct ttgtcttatt atctaggtcg
     7441 ttcaatcaaa aaagaaagtc aaaaaccgct tacatgattt tctgtagaaa tggggctatc
     7501 ttttgctctg gtcttgtgtt atactagata ggttgcaaag aaaacagtac ttttcttttg
     7561 tggaaaagaa gcaacacgat tttatatcta gttatatgaa aatacgtcat aaaaagaaaa
     7621 gtataaacta agccctatag ggtggcttcg caccaccttt agaaagaaga ataacgtgaa
     7681 atttaatgaa ttaaacttgt ctgctgattt gctagcagaa attgaaaaag ctggttttgt
     7741 agaagctagt cctatccaag aacaaactat tcctttggcc cttgaaggca aggatgttat
     7801 cggtcaagct cagactggta caggaaaaac tgcagccttt ggcttgccta cccttgaaaa
     7861 aatccgtaca gaagaagcga ctatccaagc cttggtcatc gctccaactc gtgaactagc
     7921 tgtccaaagt caagaagaac tcttccgctt tggtcgtagt aagggagtca aagtccgttc
     7981 agtatatggc ggatcaagca ttgaaaaaca aattaaggct cttaaatctg gtgcccatat
     8041 cgtggtggga actccaggtc gcctcttgga cttgattaaa cgcaaggcct tgaaattaca
     8101 agacattgaa acccttatcc ttgacgaagc ggatgaaatg cttaacatgg gcttccttga
     8161 agacatcgaa gccattattt cccgtgtacc tgagaaccgt caaactttgc ttttctcagc
     8221 aactatgcca gatgccatca aacgtatcgg tgttcagttt atgaaagccc ctgaacatgt
     8281 caagattgcg gctaaggaat tgacaacaga attggttgac cagtactata tccgtgttaa
     8341 ggaacaagaa aaatttgaca ccatgactcg tctcatggat gtggcacaac cagaactcgc
     8401 tattgtattt ggtcgtacca aacgccgtgt ggatgaattg actcgtggtt tgaaaattcg
     8461 tggcttccgt gcagaaggaa ttcatggcga cctagaccaa aacaaacgtc ttcgtgtcct
     8521 tcgtgacttt aaaaatggca atcttgatgt tttggttgcg acagacgttg cagcgcgtgg
     8581 tttggatatt tcaggtgtga cccatgtcta caactacgat attccacaag atcctgagag
     8641 ttatgttcac cgtatcggtc gtacaggtcg tgctggtaag tcaggtcaat ctattacttt
     8701 tgtttctcca aacgaaatgg gttaccttca aatcattgaa aacttgacta agaaacgcat
     8761 gaaaggtctc aaacctgcaa gtgtagaaga atccttccaa tcaaaaaaac aggtagctct
     8821 caagaaaatc gaacgtgatt ttgcagatga aaccattcgt gccaactttg agaaatttgg
     8881 taaggatgct cgcaaattgg ctgctgagtt tactccagaa gaattggcaa tgtatatctt
     8941 gagtctgaca gtccaagatc cagatagcct tccagaagtg gagattgcac gtgaaaaacc
     9001 actaccgttt aaaccatcag gtaatggttt cggtggtaaa gctaagggag gtcgtggagg
     9061 ccgtcgtggg gacgaccgtc gagagcgtga tcgccgtggc aatggtcgcc gtgatgagtt
     9121 caaaaaagga agtcgtggca acgatcgttt tgataaggaa aaacgttacc gtaaggataa
     9181 taaaaaacca cgcaatactt taagcgaaaa gcaaacaggc tttgttattc gtaacaaggg
     9241 cgataaataa gaaaaagcgg ttcaaaatga atcgcttttt tatataagga gaccgaatgt
     9301 gaaaagacaa ataaaattat tatattatct tttataatgt tatgatacac aaaaataggc
     9361 aacttgtcaa tagaaaagga acaatttaat taaaaatatt ctggttttta attaaattgt
     9421 aagtcaatgc aagtcaataa ggaattttca gataattatt gaaaaagaga cgtttttatg
     9481 ttataatgat agcgattaaa ttcgaggtga aaaatggcac atttattaga aaaaactaga
     9541 aaaattacat caattttgaa acgctcagag gagcagttgc aggatgagct tccttacaac
     9601 gctattacgc gtcagttagc ggatattatt cattgcaatg cctgcattat caatagtaag
     9661 ggacgtctgc ttggctattt tatgcgttat aaaacaaata cagatcgcgt agagcaattc
     9721 ttccaaacta agattttccc agatgactac gttcaagggg ctaatatgat ttacgaaaca
     9781 gaagcaaact tgcctgttga gcatgatatg agtattttcc ctgttgagag tagagatgat
     9841 tttccagatg gcttgacgac tattgcaccg attcatgtat cggggattcg ccttggttct
     9901 ttgattattt ggcgtaatga taaaaaattc gaagatgagg acttggttct tgttgagatt
     9961 gccagtaccg ttgttgggat tcagcttctt aacttccaac gtgaagaaga tgagaaaaat
    10021 attcgtcgtc gtactgctgt caccatggcg gtcaataccc tttcttactc cgaactccgt
    10081 gctgtttcag caattttagg ggaattaaat ggaaatgaag ggaagttgac tgcgtcagtg
    10141 attgcagatc gtatcggaat cactcgctct gtgattgtca atgctcttcg taaacttgag
    10201 tctgcgggga ttattgaaag tcgctcactt ggaatgaagg gaacctatct taaggtcttg
    10261 atttcagata tttttgaaga agtgaagaaa agagattact aatgacaaag gctttaattt
    10321 cgattgatta tacagaagat tttgttgctg atagtgggaa actaacagca ggtgctccag
    10381 ctcaggcgat ttcggatgcc atcagcaagg taactcgatt agcttttgaa cgaggagatt
    10441 atatcttctt tactattgat gctcatgaag aaaacgattg tttccatccg gaaagtaagt
    10501 tatttcctcc tcataatctg attgggacga gtggacggaa tttatatgga gatttgggga
    10561 tcttttatca agagcatggt tcagacagtc gtgtcttttg gatggataaa cgccattact
    10621 cagctttttc agggactgac ctagatattc gtttgagaga gcgtagagtg tctaccgtta
    10681 tcttaacagg tgtcttgacg gatatctgtg tcctacatac agctatagat gcctataatc
    10741 taggatatga catcgagatt gttaaaccag ctgttgcttc catctggcct gaaaatcatc
    10801 aatttgccct aggtcatttc aaaaatacac tcggagctaa gttagtagat gaaaatctaa
    10861 atgaactttc tgagtaacct ggttggtgaa aatgaaaaaa tttgaaaaaa agtgttgaca
    10921 agcatcccaa aagttgatat actagtaaag taatcgatgc ggggatggcg gaattggcag
    10981 acgcgcagga ctaaggatcc tgtgaccgct ttaggtcgtg agggttcaag tccctctctc
    11041 cgcataggaa aagagctagc taaagctagc tcttttgtat ttctctaaaa aattagaatc
    11101 cagtcaaatg tagtggagaa tcagcgaaaa tatgggaaaa ctgatccttg tttctgcttt
    11161 tgtcatagaa gaataataaa gattatcttc ttcaaattct ccgatattct ctaaagtttt
    11221 gtgcaagttg cacagaactt ttttattttt ttggtcatct tgccatagaa atataaagcg
    11281 ttttcatcta taatataatt atcaaaagac aaaaggagtt cacctcatgg tagaattgaa
    11341 tcttaaaaat atttacaaaa aatatccaaa cagcgaacac tattcagttg aagatttcaa
    11401 cttgaacatc aaagataaag aatttatcgt tttcgtagga ccttcaggat gtggtaaatc
    11461 aactacactc cgtatgattg ctggtcttga agacattaca gaaggtactg catctatcga
    11521 tggcgtggtt gtcaacgacg tagctccaaa agaccgtgat atcgccatgg tattccaaaa
    11581 ctacgctctt tacccacaca tgactgttta tgacaacatg gctttcggtt tgaaattgcg
    11641 taaatacagc aaagaagaca ttaacaaacg tgttcaagaa gcagctgaaa tacttggatt
    11701 gaaagaattc ttggaacgta aaccagctga cctttcaggt ggtcaacgtc aacgtgttgc
    11761 catggggcgt gcgattgtcc gtgatgcgaa agtattcttg atggacgaac ctttgtcaaa
    11821 cttggatgcc aaacttcgtg tatcaatgcg tgctgaaatc gctaaaattc accgtcgtat
    11881 cggagctaca actatctatg taactcacga ccaaacagaa gcgatgacac ttgcagaccg
    11941 tatcgttatt atgtcagcta ctaagaaccc tgctggtaca ggtactatcg gacgtgtaga
    12001 acaaatcggt actcctcaag aagtttacaa aaatccagtt aacaaattcg ttgcaggatt
    12061 catcggaagc ccagctatga acttcatcaa cgtgaaattg gttggtagcg aaattgtttc
    12121 tgacggtttc cgtttgaaag tgccagaagg agcattgaaa gttcttcgtg aaaaaggcta
    12181 cgaaggaaaa gaattgatct ttggtatccg tccagaagac gtgaatgcag aacctgcttt
    12241 ccttgaaaca ttcccagact gtgttgtaaa agcgactatc tctgtatcag aactgcttgg
    12301 ttcagaatct cacctttact gccaagttgg taaagacgag tttgttgcaa aagttgatgc
    12361 tcgtgactac ttgcaaacag gtgcaacagt tgagcttgga tttgacttga acaaagcaca
    12421 cttcttcgat gtagaaactg aaaaaacaat ctactaaaat aaataaaatt caaagcacta
    12481 caagaaaaga tatctcttta tcaattgtag tggagagata tcagttaatc tagggagaga
    12541 aacaaaatgc ttctctcctt tttgctaggg aagtcatatt atgcatctat attgtgatgc
    12601 tctttaatac tcttcgaaaa tctcttcaaa ccacgtcaac gtcgccttgc cgtacgtatg
    12661 attactgact tcgtcagttt tatctgcaac ctcaaagctg tactttgagc agcttacggc
    12721 tagtttccta gtttgctctt tgatttccat tgagtattat ttgtgggtac catctacaag
    12781 tgaagctata tgcgtaaact acgtgagcaa ttgaattcga actagagagg taataataaa
    12841 tttatgctat agttatggtg acttgtatgc ttttgattct agtttatcaa ataatagatt
    12901 agaattgtca gataatatca ttttgtgtta taatgaagaa aaaacagagg tgttcaaatg
    12961 tcagaagcag gtcataagtt tttagcaaaa ttggggaaaa aacgcttacg tccaggtgga
    13021 aagcgtgcca cagattggtt aattgcagaa ggaggatttt caaaagaaaa gagaatacta
    13081 gaggttgcgt gtaatagggg aactacagca attgagttgg cacagcgttt tggttgcaag
    13141 ataactgctg ttgatatgga tgctcaagct ttagaagtgg ctaaaaaatc tgctggaacg
    13201 gcaggtgttg ctcatttaat cagttttgaa agagcaaatg caatgaaact tccttatcaa
    13261 gatgctagtt ttgatattgt tataaatgaa gctatgctga ctatgcaagc cgatcaagct
    13321 aagaaaaaat gtgtaatgga atatctaagg gtattaaaac ctggaggtct tctcttgaca
    13381 catgatgtgc ttcttaagga agctaaagag tctatcagac aggaattatc acaagcaatt
    13441 catgtaaatg taggtccttt aactcaagat ggttgggaac aggtgatgat agaatcaggt
    13501 tattgtgatg tgaaagcatt gactggtgaa atgacattaa tgaaattatc gggtatgatt
    13561 tatgacgaag gtttgctagg aactttgaaa atttgtgtaa atgcttgtaa aaaggagaat
    13621 agaaagcagt ttttaactat gtataaaatg tttgctaaga ataaacagaa attgggcttt
    13681 attgcgatgg ctagttataa atcgtcaaaa cgttagataa ttattgaagt taacttttcc
    13741 ttttttcttt cttaaaaaat atgctataat agagagtaaa aaactttgaa agaaagaaaa
    13801 agatgaattt aaaagattac attgcaacaa ttgaaaatta tccaaaggaa ggcattacct
    13861 tccgtgatat tagtcctttg atggctgatg gaaatgctta tagctacgct gttcgtgaaa
    13921 tcgttcagta tgctactgac aagaaagtcg acatgatcgt gggacctgaa gctcgtggat
    13981 ttatcgtggg ttgtccagtt gcctttgagt tgggaattgg ttttgcgcct gttcgtaagc
    14041 caggtaaatt gccacgcgaa gttatttctg ctgactatga aaaagagtac ggtgtcgata
    14101 ctttgactat gcacgcggat gccattaagc caggtcaacg tgttcttatt gtagatgacc
    14161 ttttggcgac aggtggaact gttaaggcaa ctatcgagat gattgaaaaa cttggtggtg
    14221 ttatggcagg ttgtgccttc cttgttgaat tggatgaatt gaacggccgt gaaaaaattg
    14281 gtgactacga ctacaaagtt cttatgcatt attaatgaaa acagtcccta gggctgtttt
    14341 ctctacacta ggatataaaa atagactata actagttaga gaaaaactat aattgaaaac
    14401 tatatcttct tgcagtataa taaaaggact aagtgtttga gatttgtctt caaacatatg
    14461 caattattcc tgaaagagta cagttaggag agggttatgc cgattcgaat tgataaaaaa
    14521 ttgccagctg ttgagatttt acggacagag aatatctttg tcatggatga tcaacgtgct
    14581 gcccaccaag atatccgtcc tttgaagatt ttaattttaa atctcatgcc acagaaaatg
    14641 gtcacagaga cccagttgtt gcgccacttg gctaatacac ccctacaact ggatattgat
    14701 tttctctata tggagagcca ccgttctaaa acaactcgtt cagagcacat ggagaccttc
    14761 tataaaactt ttcctgaagt caaggatgag tattttgatg ggatgatcat cacgggtgct
    14821 ccagttgagc atttaccatt tgaggaagtg gactattggg aggaatttag acagatgctt
    14881 gagtggtcta agactcatgt ctattcgacc cttcatatct gttggggggc tcaggctggg
    14941 ctttatctgc gctatggtgt agaaaaatac cagatggaca gtaagctatc aggtatttat
    15001 cctcaggaca ccctaaaaga gggtcacctt ctatttagag gctttgatga tagctatgta
    15061 tcccctcatt cacggcacac ggagatttct aaggaagagg tcttaaacaa gaccaatctc
    15121 gagattttat cagaaggacc tcaggttggg gtttctattt tggccagtcg tgatttacga
    15181 gaaatttata gttttggtca tttggagtat gaccgtgata ccttggcaaa agagtatttt
    15241 cgagatcgtg atgcaggttt cgacccacat attccagaaa attactttaa agatgatgat
    15301 gttaatcagg taccttgtct ttgttggtct tcatctgcag ccctcttttt cagtaattgg
    15361 gtaaaccatg cggtctatca ggagacgcct tttgactgga gaaagataga agatgatgca
    15421 tctgcatata ggtatttata agaggaatta tgacatattt agacgctttt aaatcaggta
    15481 ccttggtttt accgagtgcc ctgctcttgc attttaagga actctttcct tctagcgacg
    15541 attttctggt ttggcaattt ttctatttgc aaaatacgac aggcttagaa gaaatatcgc
    15601 caagccagat tgctgaaagg attggcaagg aaatttcgga tgtcaaccag tccatttcta
    15661 atctgacgga aaggggactg ctccagtatc gtactatcga attaaatggc gaaattgaat
    15721 tgctctttga tgctagtttg gccttggaac gtttggatga cctgtttgga gcagttcatt
    15781 caagttcaga ccagctaaca ccacaaaacc agctcaagga tttggtggaa accttccagc
    15841 aggagttggg acgattgttg acgccttttg agattgagga tttgaccaag acactaaagg
    15901 aagatggaac cagtgctgac ttgattaagg aggctcttcg tgaagctgtt ttgaacggaa
    15961 aaccaaactg gaagtacatt caggcgattt tgagaaactg gcgccatgaa ggaatcaaga
    16021 gtgtggctca aattgaggcc aagagagcag aaagagaagc aagcaatcct cagttgacac
    16081 aggtatctgc agatttcata aatgccatgg atctctggaa ggattaatcc atgcaagtag
    16141 gcttgaaatc cgagtaagat ttgcaagctg tgtataattg tgatagaata aatagaaaat
    16201 aaattgaaaa aagaggtatg tgaaatgtca cgtaaaccat ttatcgctgg taactggaaa
    16261 atgaacaaaa atccagaaga agctaaagca ttcgttgaag cagttgcatc aaaacttcct
    16321 tcatcagatc ttgttgaagc aggtatcgct gctccagctc ttgatttgac aactgttctt
    16381 gctgttgcaa aaggctcaaa ccttaaagtt gctgctcaaa actgctactt tgaaaatgca
    16441 ggtgctttca ctggtgaaac tagcccacaa gttttgaaag aaatcggtac tgactacgtt
    16501 gttatcggtc actcagaacg ccgtgactac ttccatgaaa ctgatgaaga tatcaacaaa
    16561 aaagcaaaag caatctttgc gaacggtatg ctcccaatca tctgttgtgg tgaatcactt
    16621 gaaacttacg aagctggtaa agctgctgaa ttcgtaggtg ctcaagtatc tgctgcattg
    16681 gctggattga ctgctgaaca agttgctgcc tcagttatcg cttatgagcc aatctgggct
    16741 atcggtactg gtaaatcagc ttcacaagac gatgcacaaa aaatgtgtaa agttgttcgt
    16801 gacgttgtag ctgctgactt tggtcaagaa gtcgcagaca aagttcgtgt tcaatacggt
    16861 ggttctgtta aacctgaaaa tgttgcttca tacatggctt gcccagacgt tgacggtgcc
    16921 cttgtaggtg gtgcgtcact tgaagctgaa agcttcttgg ctttgcttga ctttgtaaaa
    16981 taatcagtaa gtagcaaaag ctaggtggaa cagcattcag atgtctgtta cattttttat
    17041 aggagagaaa gattgaaaac aaaaattgga ttagcaagta tctgtttact aggcttggca
    17101 actagtcatg tcgctgcaaa tgaaactgaa gtagcaaaaa cttcgcagga tacaacgaca
    17161 gcttcaagta gttcagagca aaatcagtct tctaataaaa cgcaaacgag cgcagaagta
    17221 cagactaatg ctgctgccca ctgggatggg gattattatg taaaggatga tggttctaaa
    17281 gctcaaagtg aatggatttt tgacaactac tataaggctt ggttttatat taattcagat
    17341 ggtcgttact cgcagaatga atggcatgga aattactacc tgaaatcagg tggatatatg
    17401 gcccaaaacg agtggatcta tgacagtaat tacaagagtt ggttttatct caagtcagat
    17461 ggggcttatg ctcatcaaga atggcaattg attggaaata agtggtacta cttcaagaag
    17521 tggggttaca tggctaaaag ccaatggcaa ggaagttatt tcttgaatgg tcaaggagct
    17581 atgatgcaaa atgaatggct ctatgatcca gcctattctg cttattttta tctaaaatcc
    17641 gatggaactt atgctaacca agagtggcaa aaagtgggcg gcaaatggta ctatttcaag
    17701 aagtggggct atatggctcg gaatgagtgg caaggcaact actatttgac tggaagtggt
    17761 gccatggcga ctgacgaagt gattatggat ggtactcgct atatctttgc ggcctctggt
    17821 gagctcaaag aaaagaaaga tttgaatgtc ggctgggttc acagagatgg taaacgctat
    17881 ttctttaata atagagaaga acaagtggga accgaacatg ctaagaaaat cattgatatt
    17941 agtgagcaca atggtcgtat caatgattgg aaaaaggtta ttgatgagaa cgaggtggat
    18001 ggtgtcattg ttcgtctagg ttatagcggt aaagaagaca aggaattggc gcataacatt
    18061 aaggagttaa accgtctggg aattccttat ggtgtctatc tctataccta tgctgaaaat
    18121 gagaccgatg ctgagaatga cgctaaacag accattgaac ttataaagaa atacaatatg
    18181 aacctgtctt accctatcta ttatgatgtt gagaactggg aatatgtaaa taagagcaag
    18241 agagctccaa gtgatacaga tacttgggtt aaaatcatca acaagtacat ggacacgatg
    18301 aagcaggcgg gttatcaaaa tgtgtatgtc tatagctatc gtagtttatt acagacgcgt
    18361 ttaaaacacc cagatatttt aaaacatgta aactgggtag cggcctatac gaatgcttta
    18421 gaatgggaaa acccttatta ttcaggagaa aaaggttggc aatatacctc ttctgaatac
    18481 atgaaaggaa tccaagggcg cgtagatgtc agcgtttggt attaagcgat gatttgaaag
    18541 agggatgtga tagtagcacc ctctttttct ttgttttatg atagttcatc ctcgagtaaa
    18601 ttcaagatct tgctcggaaa tgaagcttat gaagcttata tagtagattg aatatagata
    18661 aagaccttgt gattggtaaa acattttaga aattcattta cctttcctaa tcgacttggt
    18721 ttcatcttat ttcaatctat tatagtattg gggaatttct tcaaaccaca tcagcttggt
    18781 cagttctacc tgcgacctca aaacttgtgc tttggtcaag ctgggtttag tttcctagtt
    18841 tgctgatgga tttccattga ctataagcat ccaaccctct ttttgtcttc taaagaattc
    18901 ttaaattatc agtctattgc aacttttctc atataagttc tttgtcttgc tattggtttt
    18961 ccttagtagt atactaaggt agtaatcatt aagaagtggt tacaaaaaat aatgaatgag
    19021 gtaaaataaa atggtagaat tgaaaaaaga agcagcaaaa gatgtcgcaa cattgacaaa
    19081 agcagcgcca gtagcattgg caaaaacaaa ggaagtcttg aaccaagctg ttgctgattt
    19141 gtatgtagct cacgttgctt tgcaccaagt gcactggtat atgcatggtc gtggtttcct
    19201 tgtatggcat ccaaaaatgg atgagtacat ggaagctctt gacggtcaat tggatgaaat
    19261 cagcgaacgc ttgattacac tcggtggaag cccattctct actttgacag agttccttca
    19321 aaacagtgaa atcgaagaag aagctggtga ataccgtaat gttgaagaaa gcttggaacg
    19381 tgttctagct atttatcgct acctcatcac tcttttccaa aaagcgttgg atgtgactga
    19441 cgaagaaggc gatgatgtta caaacgatat ttttgttggt gctaaggctg aacttgagaa
    19501 aacagtttgg atgcttgccg cagaacttgg acaagcacct ggtttgtaag aaacaagaca
    19561 acatagataa atctgtagga aatttcttac agattttttc tattttgtaa gctattccaa
    19621 accagtcttt ttttgagttt tttgataaaa tagtactatc agtgaaaagg atggaagcat
    19681 gactaagaaa atcgtagcta tttgggccca ggatgaagag ggtgtgattg gtaaggacaa
    19741 tcgtctgcct tggcatttgc cagcagaatt tcagcacttt aaagaaacaa ctctgaatca
    19801 tgctatcttg atggggcggg taacctttga tggaatgggg cgtcgcttgc ttccaaaacg
    19861 ggagaccctg attttgacgc gtaatccgga agaaaagata gatggggttg ctacttttca
    19921 ggacgtccag tctgttcttg actggtatca ggctcaagaa aagaatctct acattatcgg
    19981 tgggaagcaa atttttcagg cttttgaagc ttaccttgat gaagtgattg tcactcacat
    20041 tcatgctcgg gtggaaggag atacctattt ccctgaagag cttgacttgt ctctttttga
    20101 gacagtttca agcaaatttt acgccaaaga tgagaagaat ccttatgatt ttaccatcca
    20161 ataccgcaag agaaaggaag tttaatggaa cggagtttat ttggtctatt cacggctttt
    20221 ctgtgtttca tctgctttct ggcaggagca caagcttttc gtaaaaagcg ttacgggctt
    20281 tctatcctcc tttggttaaa tgcctttacc aatctggtca atagtattca tgctgtttac
    20341 atgaccttat tttagataga atgacagtat agaatggaag gaaatcatgt ctacaaatag
    20401 aaaaaatgat atgatggttt attgctcatt ttgtggcaaa aaccaagaag aagtacaaaa
    20461 aataattgct ggcaacaatg cttttatttg taatgaatgc gtggagttag ctcaggaaat
    20521 cattcgagaa gaattggttg aggaagtctt ggcagacttg tctgaggtgc caaaaccaat
    20581 tgaactcctc catatcttga accactatgt aattggtcaa gatcgtgcca agcgtgcctt
    20641 ggcagtggcg gtttataacc actacaaacg catcaatttc cacgatacac gcgaagagtc
    20701 agaagatgtg gatttgcaga agtcaaacat tttgatgatt ggcccaactg gttcagggaa
    20761 aactttcctt gcccagacct tggctaagag cttaaatgta ccttttgcta ttgcggatgc
    20821 gacagctctg acggaggctg gttatgtggg tgaggatgtg gaaaatatac tcctcaaact
    20881 cttgcaggtt gctgacttta acatcgaacg tgcagagcgt ggcattatct atgtggatga
    20941 aattgacaag attgccaaga agagtgagaa tgtgtctatc acacgtgatg tttctggtga
    21001 aggggtgcaa caagcccttc tcaagattat cgagggaact gttgctagcg taccgcctca
    21061 aggtggacgc aaacatccac aacaagagat gattcaagtg gatacaaaaa atatcctctt
    21121 catcgtgggt ggtgcttttg atggtattga agaaattgtc aaacaacgtc tgggtgaaaa
    21181 agtcatcgga tttggtcaaa acaataaggc gattgacgaa aacagctcat acatgcaaga
    21241 aatcatcgct gaagacattc aaaaatttgg tattatccct gagttgattg gacgcttgcc
    21301 tgtttttgcg gctcttgagc aattgaccgt tgatgacttg gttcgcatct tgaaagagcc
    21361 aagaaatgcc ttggtgaaac aataccaaac tttgctttct tatgatgatg ttgagttgga
    21421 atttgacgac gaagcccttc aagagattgc taataaagca atcgaacgga agacaggggc
    21481 gcgtggactt cgctccatta tcgaagaaac catgctagat gttatgtttg aggtgccgag
    21541 tcaggaaaat gtgaaattgg ttcgcatcac taaagaaact gtcgatggaa cggataaacc
    21601 gatcctagaa acagcctaga ggtgactatg gaacttaata cacacaatgc tgaaatcttg
    21661 ctcagtgcag ctaataagtc ccactatccg caggatgaac tgccagagat tgccctagca
    21721 gggcgttcaa atgttggtaa atccagcttt atcaacacta tgttgaaccg taagaatctc
    21781 gcccgtacat caggaaaacc tggtaaaacc cagctcctga acttttttaa cattgatgac
    21841 aagatgcgct ttgtggatgt gcctggttat ggctatgctc gtgtttctaa aaaggaacgt
    21901 gaaaagtggg ggtgcatgat tgaggagtac ttaacgactc gggaaaatct ccgtgcggtt
    21961 gtcagtctag ttgaccttcg tcatgacccg tcagcagatg atgtgcagat gtacgaattt
    22021 ctcaagtatt atgagattcc agtcatcatt gtggcgacca aggcggacaa gattcctcgt
    22081 ggtaaatgga acaagcatga atcagcaatc aaaaagaaat taaactttga cccaagtgac
    22141 gatttcatcc tcttttcatc tgtcagcaag gcagggatgg atgaggcttg ggatgcaatc
    22201 ttagaaaaat tgtgaggaaa agaaaatggc aaaaacaatt catacagata aggccccaaa
    22261 ggctatcgga ccctatgttc aaggaaaaat cgttggcaac cttttgtttg ctagcggtca
    22321 agttccccta tcccctgaaa ctggggaaat tgtaggagag aatatccaag aacagacaga
    22381 gcaagtcttg aaaaacatcg gtgctatttt ggcagaagca ggaacagact ttgaccatgt
    22441 tgtcaaaaca acttgtttct tgagcgatat gaacgacttt gttcctttta atgaggttta
    22501 ccaaacggcc ttcaaagagg aattcccagc tcgttcagct gtggaggtag ctcgtcttcc
    22561 tcgtgatgta aaagtcgaaa ttgaagtcat cgcagagatt ggataagcta gttgaagttt
    22621 ggtgttgcca aacttctttt gatataagga gaaaaagatg acaaagaaac aacttcactt
    22681 ggtgattgtg acagggatga gtggcgcagg gaaaactgta gccattcagt ccttcgagga
    22741 tctaggttat ttcaccattg ataatatgcc gccagctctc ttgcctaagt ttttgcagct
    22801 ggttgaaatt aaggaagaca atcctaagtt ggccttggta gtggatatgc gtagccgttc
    22861 tttcttttca gagattcaag ctgttttgga tgagttggaa aatcaagatg gtttggattt
    22921 caaaatcctc tttttggatg cggctgataa ggaattggtc gctcgttaca aggaaaccag
    22981 acggagtcac ccactagcag cagacggtcg tattttagat ggaatcaagt tggaacgtga
    23041 actcttggca cctttgaaaa atatgagcca aaatgtggtg gatacgactg aactcactcc
    23101 acgtgagctg cgcaaaaccc ttgcagagca gttttcagac caagaacaag ctcagtcttt
    23161 ccgtatcgaa gtcatgtctt tcggatttaa gtatggaatc ccgattgatg cggacttggt
    23221 ctttgatgtc cgtttcttgc caaatcccta ttatttacca gaactgagaa accaaacggg
    23281 tgtggatgaa cctgtttatg attatgtcat gaaccatcct gagtcagaag acttttatca
    23341 acatttattg gccttgattg agccgattct gccaagttac caaaaggaag gtaagtccgt
    23401 tttgaccatt gccatgggat gtacgggtgg acaacaccgt agtgtggcat ttgctaaatg
    23461 cttggcgcag gacttatcca agaattggtc tgttaatgaa gggcatcgcg acaaagaccg
    23521 cagaaaggaa acggtaaacc gttcatgaga aaaccaaaga taacggtgat tggtggaggg
    23581 actggaattc ccgtcattct aaaaagtctg cgggaaaaag atgtggaaat cgcagctatc
    23641 gtgacggtgg cagatgatgg tggttcttca ggtgaactcc gaaaaaatat gcaacagttg
    23701 acaccgccag gtgatcttcg taatgtcctt gtggccatgt cggatatgcc taagttttat
    23761 gagaaggtct ttcagtatcg gttctctgag gatgccggag cctttgctgg ccatccattg
    23821 ggaaatctca tcattgctgg cttgtcagaa atgcagggtt caacctataa tgccatgcag
    23881 ttattgagca aatttttcca tacaacaggg aaaatttatc cttccagtga ccatcctttg
    23941 acccttcatg cagtctttca ggatgggaca gaagtggttg gagagagtca tattgtagac
    24001 catcgaggca tagttgacaa tgtctatgtg actaatgctc taaacgatga tacgcctctg
    24061 gccagccgtc gagtagtgca gaccatcctt gaaagtgaca tgattgtcct agggccaggt
    24121 tccctcttta cctctatttt gcccaatatc gtgattaagg aaattgggcg ggctcttttg
    24181 gaaaccaagg cagaaattgc ctatgtctgc aatatcatga cccaacgtgg ggagacggaa
    24241 cactttacag atagcgacca cgtggaagtc ttgcatcgtc accttggtcg cccttttatc
    24301 gacactgtct tggtgaatat tgaaaaagtg cctcaggaat acatgaattc caaccgtttt
    24361 gatgaatact tagtgcaagt ggaacacgat tttgtaggtc tttgtaagca agtttcgcgc
    24421 gtgatttcat ctaacttcct tcgtctggaa aatggcggtg ccttccacga tggagatttg
    24481 attgtggacg agttgatgcg cattatacag gtgaaaaaat gagtttcaca gtagcagtaa
    24541 aagaagaaat cctgggccaa caccatctga gctggcatga attatctgcc attatcaaaa
    24601 tgtctggtag catcggtctc tcgacttcgg gcttgacttt gtcagttgtg acagaaaatg
    24661 ccaaactggc ccgtcacctc tatgagtcct ttcttcattt ctatgaaatc aaatctgaaa
    24721 ttcgtcacca ccaacgtagc aatcttcgca agaatcgcgt ctataccgtt tttacagatg
    24781 aaaaggtgca ggatttgtta agtgatttgc acttggcaga ctctttcttt ggcctggaaa
    24841 caggtattga tgaggcgatt ttatcggatg aggaagcagg tcgtgcctat ctctgtggcg
    24901 ctttcttggc aaatgggagc attcgtgacc ctgagtcagg caagtaccag ttggaaatca
    24961 gttctgttta tctggaccac gcgcaaggaa ttgcctccct tctccaacag tttttactgg
    25021 atgccaaggt gcttgagcgc aagaaggggg ctgtgaccta tctccagcga gcagaagaca
    25081 ttatggactt cttgatagta atcggagcca tgcaggcacg tgatgatttt gagcgggtta
    25141 agattttgcg agaaacccgt aacgacctca atcgggctaa taatgccgag acagctaata
    25201 tcgctcggac agtttctgcc agcatgaaga ccattaacaa tatcagtaaa atcaaagata
    25261 tcatgggctt agaaaatttg ccagtagatt tgcaggaagt ggcgcaactg aggattcagc
    25321 acccagacta ctctatccag cagttagcag atagtctcag cacccctctg accaaaagtg
    25381 gtgtcaatca cagactcaga aaaatcaata agatagcgga tgaattataa cgatataaag
    25441 caaccccttg aattatcaat atcttcaagg ggttttgttg tgttatgaaa tcaaaaaggg
    25501 gcaaccaagg ggcagaatta aaaaatagta tctaatttat tgaccagttt atcctccata
    25561 tcctcagtag tatgagaata gatttccaaa gtcatttttg catttgagtg cccaactcga
    25621 tccattattg attttattgg gaggccagac tctgctaaaa acgaaatatg agaatgccta
    25681 aaaatatggc tagataagtt tttttctatt ttggcctgtt ttccatattt ttttaatatc
    25741 tgtatgaagc aagctattgt tgtaggttga ttccattttt caaaacagaa aatataatca
    25801 tcgcttgaca atggctggaa acgttcgcta agtcgtacta tttgtctttg aatagcttct
    25861 atgacactct ctgatacttt gattgtccgt attgaatttg tagtctttgg tagcgtcttg
    25921 attttgttta ctgaatcaaa attacctgtg atctcaattt tgttgttttc gaagtctata
    25981 ttcttcagtt gtaaggcagt taactcacca tatctcatac cagttaatgt cagcacaaga
    26041 accatatcag cgtacttttg gtgatattct cgacgattaa ggacatcgac aagtgctttt
    26101 atttcttgca tggtgagaaa gttgttacgc tttttttcca gttcttctaa agtctttggt
    26161 ttttgaggaa tcgtagtata atcgacctcg ttgttttcaa tgtaagagta ttgaacagcg
    26221 taattaaaga tacctctgag cctatgccgt acttttttag ctgtaatata tccgttgctt
    26281 tcaataattt tttcaatagc ctcttgaaga aaacgcctgt caagattagc aagtatggta
    26341 tcggatggta tgacttcctt catcttctta tcaactgatt tacaattatg ttttgttgat
    26401 tcctttactg tttgcgccca tgatttatag aaaaggttat agatttcttc aaatgtaatg
    26461 ctttctactt gttttgtgct gagtttttta tttatcttct cttgtaacaa gatagcagct
    26521 tgatttcttg cctggggagt tttcttctcc atggtcactg aaactttttt taatttctca
    26581 gtatatggat ctttatatcg ctcaaaaaat ttgtattttc cgttgggaag ttcttccatc
    26641 cacattgcgt ttacctcact tttttgataa aatgggtata gtaaagaggg ctttttaatg
    26701 ccttttacta tacaggatat cctcacactc tccttggcca aaatttgagt gtggggattt
    26761 tttaattttt cagcagcaaa tacgcatcga cgtaaattaa aggtacgctt ttctctttat
    26821 tactatttgt agtgtattcg taagaaagca agtaacgccc gtttacagtc aaatgatctt
    26881 tttctaaaaa tcttttttcg atacgtttag tctccatgaa cagcatatag aaatcaccgc
    26941 tgggttgtgt aacaagcatt ttcgtgtact tgccttcttt aaaaatttgt acgatctcca
    27001 gattgtcgat tctcattttt aaagagaaga atttttctgg ctctctgaga actgttttgt
    27061 aatcgtagat tttataatcg tctgacttgt aattgtcctt tgtgacctta tcaactttag
    27121 tcaatagctt atcaaaatat tcttctacgc taatatcatc agatgatgat gcctgagtgg
    27181 tcggttcgct ggatgacttt tgcgtttgat ttgtacaagc ggttgaaata acaagtgcac
    27241 aaagcaaaac agatgatatg gaaaatattc ttttcatttt atcctactcc tttttcaatt
    27301 aagtaaagcc aaatattctt cttttaccat tatttcatcg gcaatggttt ttaaattata
    27361 cttttccata aataccaggt aattaaatgt agtggcatct tcggctatac ccaactcagc
    27421 tttcataagg tgatggatca tattcctatt agcctcaagc tcacactttt cccgaaaaag
    27481 ctgataagta tctggcgcgt ggtttctatg gcctatctca tgtaaagcga cttgtaccct
    27541 tttttcatca gatatagcat cactcaaaaa catagttttg agggctggga tgtaaaaggc
    27601 ttcatctgga aatagaccat cttcaaaaat ctctatatct atgcctagat tttgagaaaa
    27661 ttctttttca gtcataaaca atccaacctt tgattattat tgttttctga gatagatctc
    27721 tattatgttt tgaattgctt ttttatcttc ttcagttagt ggtttaccat tgaagcgcat
    27781 agcagtagag gcaagttcct caacatcgac ttctttgcct tcgaaaaaga attgttcttt
    27841 tttattagcg atggtaggat tatctgtgcg accaagtaag tagtctgtag atacattgaa
    27901 gtagtcagcg attttggata tatgttcagc agatggagtc tttttatttt taagactgta
    27961 aatgtaattt ttccccaaac caaccctatc ttctaaagtg tttagagaaa ttccctgttt
    28021 tttagctaaa cttttaattt tttcgaatgt ctcaaacatt gatacatcaa cctttctgaa
    28081 gcattacaaa aaaatatttt attttttcgc ctaaaacact tgacaaaaat tagacga
//
LOCUS       DAVLGK010000029        27584 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLGK010000029 DAVLGK010000000
VERSION     DAVLGK010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27584
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.029"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(47..205)
                     /locus_tag="VXE01_001373"
     CDS             complement(47..205)
                     /locus_tag="VXE01_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV0750270.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(276..722)
                     /locus_tag="VXE01_001374"
                     /pseudo
     CDS             complement(276..722)
                     /locus_tag="VXE01_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(798..1388)
                     /locus_tag="VXE01_001375"
                     /pseudo
     CDS             complement(798..1388)
                     /locus_tag="VXE01_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1312..1506)
                     /locus_tag="VXE01_001376"
     CDS             complement(1312..1506)
                     /locus_tag="VXE01_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0750271.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEEDGDVPS"
     gene            complement(1739..2026)
                     /gene="tnpB"
                     /locus_tag="VXE01_001377"
     CDS             complement(1739..2026)
                     /gene="tnpB"
                     /locus_tag="VXE01_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV0750272.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWLSTEKDVKALAPEQVD"
     gene            complement(2007..2192)
                     /locus_tag="VXE01_001378"
     CDS             complement(2007..2192)
                     /locus_tag="VXE01_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750273.1"
                     /translation="MPQPIVPVEIPQSRLFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2496..4058)
                     /gene="guaA"
                     /locus_tag="VXE01_001379"
     CDS             complement(2496..4058)
                     /gene="guaA"
                     /locus_tag="VXE01_001379"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV0750274.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4200..4898
                     /locus_tag="VXE01_001380"
     CDS             4200..4898
                     /locus_tag="VXE01_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0750275.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4941..5837)
                     /locus_tag="VXE01_001381"
     CDS             complement(4941..5837)
                     /locus_tag="VXE01_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0750276.1"
                     /translation="MSNSLKGTLLTVVAGIAWGVSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMILAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQANIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5846..6781)
                     /locus_tag="VXE01_001382"
     CDS             complement(5846..6781)
                     /locus_tag="VXE01_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV0750277.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6778..7503)
                     /locus_tag="VXE01_001383"
     CDS             complement(6778..7503)
                     /locus_tag="VXE01_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV0750278.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(7587..8222)
                     /locus_tag="VXE01_001384"
     CDS             complement(7587..8222)
                     /locus_tag="VXE01_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV0750279.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(8224..9051)
                     /locus_tag="VXE01_001385"
     CDS             complement(8224..9051)
                     /locus_tag="VXE01_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0750280.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINTLFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9073..10390)
                     /locus_tag="VXE01_001386"
                     /pseudo
     CDS             complement(9073..10390)
                     /locus_tag="VXE01_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001189734.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10638..11249
                     /locus_tag="VXE01_001387"
     CDS             10638..11249
                     /locus_tag="VXE01_001387"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0750281.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11294..12022
                     /gene="rlmB"
                     /locus_tag="VXE01_001388"
     CDS             11294..12022
                     /gene="rlmB"
                     /locus_tag="VXE01_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV0750282.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(12061..12972)
                     /gene="trxB"
                     /locus_tag="VXE01_001389"
     CDS             complement(12061..12972)
                     /gene="trxB"
                     /locus_tag="VXE01_001389"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0750283.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELSEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLNPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13038..13262)
                     /locus_tag="VXE01_001390"
     CDS             complement(13038..13262)
                     /locus_tag="VXE01_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV0750284.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13340..14083)
                     /locus_tag="VXE01_001391"
     CDS             complement(13340..14083)
                     /locus_tag="VXE01_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0750285.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14083..14883)
                     /locus_tag="VXE01_001392"
     CDS             complement(14083..14883)
                     /locus_tag="VXE01_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0750286.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15041..15397)
                     /locus_tag="VXE01_001393"
     CDS             complement(15041..15397)
                     /locus_tag="VXE01_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0750287.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15410..15922)
                     /locus_tag="VXE01_001394"
     CDS             complement(15410..15922)
                     /locus_tag="VXE01_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV0750288.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15922..16416)
                     /locus_tag="VXE01_001395"
     CDS             complement(15922..16416)
                     /locus_tag="VXE01_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0750289.1"
                     /translation="MEIRLAFPNEVGAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16551..16997
                     /locus_tag="VXE01_001396"
     CDS             16551..16997
                     /locus_tag="VXE01_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV0750290.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGINPANPIIQTSCQTIKLYHQTLDLIDHTQEEVIQ"
     gene            16994..17641
                     /locus_tag="VXE01_001397"
     CDS             16994..17641
                     /locus_tag="VXE01_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV0750291.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17662..18243)
                     /gene="pdxT"
                     /locus_tag="VXE01_001398"
     CDS             complement(17662..18243)
                     /gene="pdxT"
                     /locus_tag="VXE01_001398"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV0750292.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18244..19119)
                     /gene="pdxS"
                     /locus_tag="VXE01_001399"
     CDS             complement(18244..19119)
                     /gene="pdxS"
                     /locus_tag="VXE01_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV0750293.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19271..20650)
                     /locus_tag="VXE01_001400"
     CDS             complement(19271..20650)
                     /locus_tag="VXE01_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0750294.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20944..21867
                     /locus_tag="VXE01_001401"
     CDS             20944..21867
                     /locus_tag="VXE01_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV0750295.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21927..22532
                     /locus_tag="VXE01_001402"
     CDS             21927..22532
                     /locus_tag="VXE01_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0750296.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22551..23795
                     /locus_tag="VXE01_001403"
     CDS             22551..23795
                     /locus_tag="VXE01_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0750297.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(24018..24275)
                     /locus_tag="VXE01_001404"
     CDS             complement(24018..24275)
                     /locus_tag="VXE01_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV0750298.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24317..26353)
                     /locus_tag="VXE01_001405"
     CDS             complement(24317..26353)
                     /locus_tag="VXE01_001405"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV0750299.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26613..27530)
                     /gene="glyQ"
                     /locus_tag="VXE01_001406"
     CDS             complement(26613..27530)
                     /gene="glyQ"
                     /locus_tag="VXE01_001406"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV0750300.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWANGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
BASE COUNT         8131 a         6185 c         5033 g         8235 t
ORIGIN      
        1 tctccagact agagaactca tatatagttc ctaatctgga gatttctcat ttgcactttt
       61 cttgtacaac tttagtccat ggtaaatagg cctctaaaac ctctttgttt acgagagttt
      121 cctcgtttgg aagacattct agaagatagg atagatattt ctcactattt agttgatgac
      181 gtttagctgt ttccaacaaa ctcataataa tagctcttgc tttagctcct tcaaaacttt
      241 gagaaaataa ccaccctcgc ttttttaaac tgagcttagg ctaaaagagt ccactggact
      301 cttttactcc gtcccataac caatgattta atggcgcatt cagctagatt attggaaagg
      361 accagatgtc cgtctttcaa aatggtctta aaggtttctt catacttgag gctgtattca
      421 attgcccttc ctagttttga acctgctaaa actgactgac ggcggcacca agcaaagaag
      481 tcttctatta ggggttggag ctcttcttga cgtttctgta gtcgttcatc agctggcaaa
      541 gcctcccagt ctctttccaa ggaaaataac tgatcacaat aggctaatcc tttagctcct
      601 aaagatgatt tatctgcttg cttgggggtc gcttcaaaaa acttccttct cacatgcgcc
      661 caacatccaa caagtgcagc ttcttccagt tgacgataag cttctagcgg ctcgcagttt
      721 accaagctta gcgtcgcctt gctcctaagc cttggactgc tatcgcatag acagaactag
      781 aggactaaag tcctaagtta ctgccgcaac atatcacaat gcacatagcc agaataatct
      841 cctaggaatt cttgtactac taaaccactc cgacgctgat catggtggta cagcgtgatt
      901 gcttgattct cagctttccc agacaaaaag gtccaatagt aggtcagctg actatcactc
      961 tctagcaccc tataagaagt ttcatctgca tgaagtaagg gcttgagtca atagtctcgt
     1021 tataaagggg ctttaggaat aggagctttc acgattttat cactcggatt tttatcactg
     1081 catgcttggc atttgtaagc gtgttggata tgatctatgc gttttaattg cgcaggaata
     1141 aagaccaatt cttgtccttg aagactccct ccaatctctt ttagatctcc ctgacaatca
     1201 gggcaaatcc tctcttctac ttgatgatga acttcttctg aatcaaattg ggcaagaaga
     1261 gcttggcgtt tccctttaga tttcttacgt ttgtaggtaa tttcctctgt ttcaactggg
     1321 aacatctcca tcttcctcag atggagactc ttcctcaaaa aggttgagtt gtccagaggg
     1381 gcaaacactt ttctcagagg attttccata gagcttttga gtcagataag ccacttgttc
     1441 acgcagaagg gcaagttcat tggtgagact atcaattgta gcactctgtt gttgaatgat
     1501 tttcaatctt cttccatgag cttccctctc tgttttctaa ctttattata ctaaaaagaa
     1561 agtcctcatt tcaatagaaa tcacgacttt ctgatggatt tatagtaaaa tgaaataaga
     1621 ataggacaaa tcgatcagga cagtaaaatc gatttctaac aatgttttag aagcagaggt
     1681 gtactattct agtttcaatc tactatattt ttggagtgat agaaaagccc ttcataagct
     1741 agtctacttg ttcaggtgcg agagctttga catccttttc tgtacttagc caagtcagtc
     1801 tgccgttctc aaagcgttta tatagtagcc aaaatccttg accatcccag taaagggctt
     1861 taaagcggtc tttacgtcca ccacaaaaga gaaaaacttg acctgagaaa ggatctaatt
     1921 caaagtgggt tttaaccaga taagccagtg aatcaatgcc ttgcctcata tccgttttcc
     1981 cacatacgag atagacctgt cctaggctag atagatgaat tgtcatagag caacacctta
     2041 tccaaaagct gttctaccat ttcgagattg agagattgaa aaaaacttac ttcaagcttg
     2101 ccaatacgaa ttttaagcag aatatcattt ctctttttag aatcaaaaag acgagattgt
     2161 ggaatctcta caggaacaat aggttgtggc attaaaatat cctccaatag ttttacttta
     2221 ctaatagtat acaggaggag ctccatgaat gatagatacc ttgttatgac gcgcttacta
     2281 tattagaaag ttggctctct aattaaatta attctcatta tatatatcaa aagaccgcag
     2341 cttgaaaact acggtctaat tttttgtcca aatgtaaacc acttggaact attattcaat
     2401 ttattctttt tagtaaatgt tcccgtttta atcccagtta cagtttttaa tcctctgtaa
     2461 ccgttgattt tacaaagctt ttaatttttt tgcgattact cccactcaac tgttgcaggt
     2521 ggtttacttg taatatcgta gacgatacgg ttaacatgat ccacttcatt tacgatacgt
     2581 actgagattt tttgaagtac ttcccatgga attttggcaa aatcagcagt cataccatcg
     2641 atagaagtga tagcacggat tgcaatcgtg tagtcatacg tacgaccgtc acccataaca
     2701 ccgactgaac gaacgcctgt gttaacagtg aagtattgcc aaatatcgcg gtcaagtcca
     2761 gctttagcga tttcttcacg aagaatagcg tctgattcac gaacggtttc aagtttctct
     2821 tcagtgattt cacccatgac acggatagca agtcctggtc ctgggaatgg ttggcgccat
     2881 acgatatggt ctggcatacc aagctctgta ccaagagcac gaacttcatc cttgtaaaga
     2941 gtattgagtg gttcaatcaa ttcaaactgc atatcttctg gaagaccacc cacgttgtgg
     3001 tgtgacttga tagtttgagc tgtatccgta ccagactcga taacatctgt atataaagta
     3061 ccttgagcaa ggaatttcac atctttgagc ttgcttgctt cgtcatcgaa tacatagaca
     3121 aactcgttac cgatgatttt acgtttttgt tcaggatcag aaacgccagc aagtttgtca
     3181 aggaaacgtt tagcagcgtc tgctttgacg atattcaaac caaacttacc accgagcatg
     3241 tccataactt gatcagcttc gcctttacga agaagaccgt ggtctacgaa gatacagatc
     3301 aattgatcgc caatcgcttt ttggagaaga accccaacga cagatgagtc aacaccacct
     3361 gatagaccaa gaaggacacg tttatcaccg acggtttcac gaattttttt gatctgcatg
     3421 tcaatgaaat tatccattga ccagtcacct ttagccttac aaatgttaag ggcaaagtta
     3481 cgaaggatat catttccgta tacagaatga cgaacttctg ggtggaattg gataccgtaa
     3541 atgtgtttat ctgggttttc gatggctgcg tatgggcagt cagctgatgt acctgtacga
     3601 acaaagtcag caggaatctc agtaaccgca tcaccatggc tcatcaaaac agtctgttca
     3661 tcaggtgttg attcaaaaag cgctgatggt gtgtgagtta gggttgattg accgtattca
     3721 cgatttccag catcacctgc aggaacaact tttcctccaa gtttatgggt caataactgc
     3781 ataccataac agattcccaa aattggaatt ccgagttcga agatttctgg gtcaatatca
     3841 aatgaaccat cttcatatac agaatttgga ccacctgata gaataattcc tacaggattg
     3901 acttcacgaa cttcagcagc tgaaatttta tggcttttta gttctgaaaa aacaccaatc
     3961 tcacggatac ggcgtgaaat cagctggttg tactggctac catagtccaa tacgatgatt
     4021 ttttctacat cttgcaaatc agttgaaatg ttgctcatct ttttcctttc tcaaaagaaa
     4081 tatcttttct caatattcta tcacaaataa gggcgaatta ccaactaaac aaggcgaagt
     4141 ttgacttttt ctagtttatt ggggtacaat agagaaaaga tagaaatgaa gtgaaaaata
     4201 tgctacctgc ttatatgaaa atccatgatc agataaaaaa ggatattgac gagcaccgtt
     4261 gggctattgg tgagaggctt cccagtgaaa gagatttagc tgagcagttt gcggtcagtc
     4321 gcatgaccct ccgccaagcc gtatctctat tagtcgaaga aggcgtctta gagcgccgtg
     4381 taggaagcgg cacctttgtt tccagtactc gagtacaaga aaagatgcga gggacaacca
     4441 gttttactga aattgtcaaa tcccaaggta aagttccctc tagccagctc atttcctaca
     4501 aaaaaaccat tcccaatgag caagaagttg ccaagctagg aatttttcca acggacaata
     4561 ttatccgaat ggagcgggtc cgctatgccg accaagttcc cctagtttat gaagttgctt
     4621 ctattcctga aaaattcatt aaggacttta aaaaagaaga aatcaccagt catttcttcc
     4681 aaaccttgca aaaacatggc tatcgtatcg gcaaatctca acagaccatc tatgctcgcc
     4741 ttgctaaaga aaagattgcc cactatttgg aagttgaaaa aggacatgct attcttggat
     4801 tgacacaggt ttcctaccta gaagatggta ctgcttttga atacgtaaaa agtcaatatg
     4861 taggcgaacg ctttgaattt tatcttgaaa ataattagat taccacgcaa aaactctctg
     4921 tcacagacaa agagtctttt ttatttttct aagaataaat ctttcaaaga aatcaaagtt
     4981 acagcaaaca atatcattgc cataccaaga aaatcaatgg gataaaattg ttcattcatt
     5041 attaagaagg caaagaaaac cgccgatatt ggctcaattg aagccaacaa gcttgacttg
     5101 accggtccta tcagactggc tcctttaagg aaagctgtat aggcaaagac agtcccgata
     5161 aggataatac ctgcaaacgc aaggagaaaa tcaagactag tcgggatatt ggcctgtaga
     5221 acccctgtaa aaggaagggc gaccaaacct gctataacca ttcccacacc aatgaccaag
     5281 ctgctccccc actttttaat caaggctatg ggtaaaatga tatatagagc ataagtcaag
     5341 gcagaaaaga gaccccagaa caggccagca ggtgtcatgg ataactggtc caactgccca
     5401 tgtgttgcga tcaggaaggt tcctccgatg gcgaatatga tggaaactat ctctcccagt
     5461 gtcggtgcca ccctatcctt gatacagcta taaattaaaa ttccgacagg acaaacatac
     5521 tgaagcaccg tcgctgttcc cgcattggtc tcctgaatag cagacagata ggcgaattgg
     5581 ttgagaaaaa gaccaatcag agcaaaaata agaagagaca gcaaactctt tctatccttt
     5641 aaaaagacca gtattttatc ctttgcagta gcataagcca agatcatgag aattccacca
     5701 gcgattaaaa gacgcaagtt ggtcaagacc agagccgaaa ttccgtgtgc cattaggtat
     5761 tggccactcg ttcctgacac cccccaagca ataccagcca caactgttag taaagtccct
     5821 tttaaactat ttgacatgtc tctccttact cttctttacg aatcaagttc atcacttgat
     5881 tgcggtctaa tatccattga gctctctcgt ccttttcata ggtacgattc gataggaaaa
     5941 tagtggcttc ttgcttctga cgattccaca tgataaaggt acctgtatag cccgtatggt
     6001 ctagccaatc tccttccaaa ttccatgcta aagaacgttc cttgtcatcc aaaggagaaa
     6061 aattttgatt taagtctctt gcaaaatcat ctgctaaata gtgttctaaa aagatttgta
     6121 aatcctttat agtcgaaaat aaaccagcac tcccagcatg tctacccagg agacgagcct
     6181 tgggatcatg cactatgcct gcctctacac ctctaactgt tggaacagca agctcaactg
     6241 gcccaaactt ggtttccgtc attccccaag gtttccagac ttgatccttt aaaatcacat
     6301 ccaaatcttg attaaaaatt ctttccaaaa taaagcccaa cagcaaaaaa tggacatccg
     6361 aataaagaaa ggctggctga cttcgtctgt tgagatgaaa catcgcttcc tttaattcag
     6421 gggctgttaa aagatcacga ttaggaataa aaggatcaag gtctgttgca tgagtcaaga
     6481 gctggcgaat agtgatgtct ggataatcac tctcaggtaa aaaatctatt accagtctat
     6541 caatatctaa ttgacctatt tcccacaaga aggtacaaac tgtgccaacc ccaacaacct
     6601 tgctgacact agctaggtca taaactagtc ctgcctcagt ctgcaagcca tgctctgggt
     6661 cactctggcc taaatagaac tctgtccatt gattgtcctt aaaatacgca aaagaggctc
     6721 cgggataaat tcctgcctcg atttgttctt ctattttttt aataatcttg gtccacttca
     6781 tacttcttca aaccacaatt caacattatt tctatcttta caaaggaaga atttttcaga
     6841 cttaggaata aaatattcag tagactcaaa cttctggcga agacttgcta tgtctaattc
     6901 attgaccaag aacttgagca tagataagtc ccaggtaacc gtattgtcca cagtcaaatc
     6961 ctgcccctga gctggaataa aatcaaggga tgccccaatt tcagatgatt ccaagaaact
     7021 ttcgatatca gttgggagat gtaattccat agaaatctca aatttactta aagaaattga
     7081 tgccaaatct gtttgaaatt caggcttttc tcctacttct actagacttg ctatgtcatc
     7141 ttccgcatga atcaaaatca aatcatcttc tggtgagaaa atttcaaaag cgtagccatt
     7201 ttgaccttta tataatcgat gaatcgaatc tgttttagat aagattcctt caatttctaa
     7261 gggattttcc accttgacaa tcaatctagc tagttttttt cttccctcta ccttacgagt
     7321 acgcatactg ggagcttctt ctaaaaccag cttttcaaga cccgtttggt cacctagtga
     7381 cagaaaggcc gattcttcta acaaggcctt cattccaagg gtttcaatat aaaatgtttc
     7441 atttaatttt ctattattag cttttaaagt aggaataatc cgtacaatct gatttacatt
     7501 cataaattcc tccgtcactt tttattttaa aggattttag aattttttac aagatattat
     7561 gctcaaattt aacattattt agctatttag taaagatagt ctttcaagga ttttgacaaa
     7621 gcctgataac cagcaatact gaggtgcagt ccatcagttg tatattcttt tttgagttgg
     7681 cctgcttggt ctgtcaaaca atcaaatact ggcacaaatt ccacctgcat ataggcagat
     7741 gcaagctctt gataggcttg attccagttc tgaatttttt cattcgagcg gatatagact
     7801 gcctgctggt actcctctcc ctcattgaca ggcaaaatgg aaagcaattt aatctctgtc
     7861 aatggataat cgcgagcaac ggattgaatg atagcttcga gattattgag agcctcattc
     7921 acaggaacat cctttccgat atcatttgtc ccaatcagaa gaaaaatttt atctactgct
     7981 ccaccatata gatgagcatc aaggttctct agtaacagtc ctgtctgata gccacgaatt
     8041 cctcgattga caatcgtctt tgaagtccca aatagctcct gtagaggata atactcgaca
     8101 atggaatccc caataaaaag aatgtttggt tctacaacag aaatgtgatt taggtgacga
     8161 tacttggttt gaattttttc ttgttccttt aggagccaat tttctaataa ctgtactgcc
     8221 acttcattct cctttttcta accagttttc caagacttga taaactcctc cttggctgtt
     8281 ggctggtgct agagcagtcg ccacagcttt ggctttctca tcagcatttt ccatcgcata
     8341 ggcaattcca gccatttcaa gcatttcaac atcattttca ctatcaccaa aagccatgat
     8401 ttcttgggat ttcaagtccc agcgcttgag taattcctcc aagccccatg ctttatgaat
     8461 cccagcttgg aggatatcaa tgcaaccata gccactggat acagctcgga cacggccatc
     8521 aaagagagta ttgatttctt ccaaaaccga actcaaacgt tcctcaccaa caaccatgct
     8581 catcttgagc acaccaccaa agaggtcaga tgttaattca tccacaaatt gcatccgttg
     8641 gtagaatttt tcaatcattt ctggagtcat aaaactttca agatctgtaa aaatcgtacc
     8701 ttccttgaca aaatcaccct tcatccccgt tacaacaaac tggtcctgac acgctcgacc
     8761 cttgaaatga gccaaagcct tgttgacaat ggcgtcatcc catgtctgag cctgaatcaa
     8821 ttcattgttt tcaaaaatac gagcgccatt agcaacaacc agaaccactc gatccaccaa
     8881 gggactcagt agttgtctca tgcggtgaat ttcattgccc gtcgcaatga caaaacgaat
     8941 gcccctttga tccaactgat ctaaaatctt ttccaatcgt gggagatcaa gctgacctct
     9001 agcatccagc aaggtcccat ccatatctgt cgcaattacc ttaatcatca tttactttcc
     9061 tctggattca agctaatacc acttcaatcc cacatgttca ttcatttctt tataggctgt
     9121 atcaattcgt tccttagtcg cttcatctaa ctggtcacga tgactgccat cctctataaa
     9181 atcttccaaa atataagttt ggtaatgata caagggatat ccttctggtg aaaaggttcc
     9241 ctttggtgtt cgattgaccc aagtaggatg atctttagct gttccgatag ttgtttttcc
     9301 atcattcttc ttgatggtga catccatgag aacaccacgt tcagtccact tagcattctc
     9361 ttcatctccc atagattcaa ttcgttgatt ggaaatgaag ttccccattg aatagataat
     9421 gagtttctta tctccatctt tttcaaccgt ttcagatggt tcaacaacgt gaggatgccc
     9481 tccaaagata atatccgctc cccaatcgat catcttgtga taaagagctt tttgttcttc
     9541 agttggttcc aatcgatact caacacccat ctgaggcatg ataatggtga tatctgcttc
     9601 cttctctgcc cgttcaactt cagccttcat cttatcttcg tttaaatcta aaagataacg
     9661 attatagtct tcctgagaaa tatactgctc aattccattg aaaccatagg aataggctga
     9721 caatgcaacc ttgataccat tcacttcctt aatgaccagc ggaacctgat cacgtggttc
     9781 gtgcgtataa actccgattg gagtgattcc agctttctca ataatatcgg ccgttgaaat
     9841 aactccctca atttgcgaat ccaaaatatg attatgagct aaatccagca catgataacc
     9901 tgcctcctta atagcatcca taacttcagc aggagcatta aagagaggat aacccgctaa
     9961 ataatgatcc ttattaatgg tttcttcaaa atcaccaata gctaaatctg cttgcttgaa
    10021 ccaaggagtc acatactcaa aattttcatg aaagtcatag gtaccgtctt cttttttagc
    10081 tgaaaagaaa agtccatcgt ggtagagcaa atccccgtgg gccataattc tggcagtttt
    10141 ttcctcttcc tactcctgag acttttgctt agttccctct tgagaaatag tatctcgttt
    10201 ttgactagta aagagattcc ttggaagctt tcaaacaaca agaccaagcc cattgataaa
    10261 ccaactgcta gcaagagtat cgccacaaat cccttattgc tccacttgcg ataactccta
    10321 aaaagtttac caagcccttc ataaaacgaa aagctaaacc accctgattt cgattttgtc
    10381 ttctttgtat cttcgttctc cctactttct tatgcaagcc ttttcttttt attatatcac
    10441 agataagtat ttctttcaca attgaattga acttcccatc tattttctat aaatcctaaa
    10501 tgccataatg ctttcaattc ttgtcatttt gtgatatcat gtagaggaaa tgaactaatc
    10561 cacagtggct tattccaagt ataccacttg ggctttggca gtagctaact gcactaaaca
    10621 taatataagg agagaaaatg tctgcaatag aacgtattac aaaagctgct cacttaattg
    10681 atatgaacga tattatccgc gagggaaatc ctactctacg cgcgattgct gaggaagtca
    10741 ctttccccct atctgaccag gaaatcatcc taggcgaaaa gatgatgcaa ttccttaaac
    10801 attcccaaga tcctgtcatg gctgaaaaaa tgggactccg cggtggtgtt ggactggctg
    10861 ctccccagtt agatatctca aaacgcatta tcgctgtttt ggtacctaat attgttgaag
    10921 aaggcgaaac tccacaggaa gcctacgatt tggaagccat tatgtacaat ccaaaaatcg
    10981 tctctcactc tgttcaagat gctgctcttg gcgaaggaga aggttgcctg tctgttgacc
    11041 gtaacgtgcc tggctatgtt gttcgccatg cccgcgttac tgttgactac tttgacaaag
    11101 atggagaaaa acaccgtatc aaactcaaag gctacaactc cattgttgtt cagcatgaaa
    11161 ttgaccacat taacggtatc atgttttacg atcgcatcaa tgaaaaagac ccatttgcag
    11221 ttaaagatgg tttactgatt cttgaataaa gaaaatcccg ttgcaagacg gggttttgtg
    11281 ttataataga ggcatgaaaa caaatgatat tgtctatggt gtccacgccg ttaccgaagc
    11341 tctccttgca aatacaggaa acaaactcta cctccaagaa gatctccgag gtaagaatgt
    11401 tgagaaagtc aaggaactag ctacagaaaa gaaggtgtcc atttcttgga catcaaaaaa
    11461 atctctctct gagatgactg aaggtgctgt tcatcaaggt tttgttctac gagtgtctga
    11521 atttgcctat agcgagctag attacatcct tgcaaaaaca cgccaagaag aaaatccact
    11581 tctattgatt ctagatggtc taaccgatcc ccataatctg ggttctatct tgcgaacagc
    11641 cgatgcgacc aatgtttcag gtgtcatcat tcccaagcac cgtgctgtcg gagtaactcc
    11701 tgtcgttgcc aaaacagcca caggtgctat tgaacacgtt ccaattgccc gagtgacaaa
    11761 cctcagtcaa accttagata aactcaagga tgaaggcttc tggacctttg gaacggatat
    11821 gaacggtact ccttgccaca agtggaatac aaaagggaaa atcgccctca tcattggaaa
    11881 tgaaggaaaa ggtatctcta gcaacatcaa aaaacaagtc gatgagatga ttaccattcc
    11941 gatgaatgga catgttcaaa gccttaatgc cagtgttgct gcggccattc tcatgtacga
    12001 agttttccga aatagactat aaaaaagttt ccagtcatct gattggaaac ttttttatga
    12061 ttaactatgt tctgtgataa acttgtaggc ttcttgacca gcgatagctc catctccaac
    12121 tgctgttgtt acttggcgaa ggtctttcaa gcgaacatct ccaactgcaa agataccgtc
    12181 gactgcagtt ttcatgtggt tatctgtcac aatccatcct gcctgatctt ggatattcaa
    12241 ttctttaaca aaatcgctaa gagggttcaa accaacatag ataaagacac caccgaaggc
    12301 ttgttctgtc acttgacctg ttttcacatt ttcaaatacg actgattcta ctcggttttc
    12361 acccttgatt tcccttacta cagaatccca gataaagctg attttttcat tcgcaaaggc
    12421 gcgatcttgt aaaacctttt gggcacgaag ttggtcacga cggtgaacaa tggtaacagt
    12481 cttagcaaaa cgagtcaaga agagggcttc ttcaacagct gaatctccac caccaactac
    12541 caataaatct tggtcacgga agaaagcacc atcacacaca gcacagtaag aaacaccacg
    12601 actgttcagt tcttcttctc caggcactcc caaaggacgg tgtttagaac cagttgctac
    12661 gataactgta cgtgtttcat atgtttggtc atcagtcatc actttcttaa aatcaccatg
    12721 gtcttcgaca ttttcaacat aaccataaat gtgctcaaca ccaagatttt caagtggttc
    12781 aaacatcttt tcagacaatt caggtccact aatattagcg tatcctgggt aattttcgat
    12841 atcagatgta ttattcatct gaccacctgg cagaccacct tcaatcaaag ctacttttag
    12901 attgcttcga gcagcataca aggccgcagt catccctgca ggtccagcac cgataataat
    12961 agtatcgtac atatagattc cttctttctt gttgtaacta tctttattct aactctttct
    13021 tgtcaatcac gcaaggatta tgccttgaaa acaagaatta aactcataac cgcaaaggat
    13081 aatactggga caaccaagac tccaatcata atcatatcat agagatgggc ttggcgagcc
    13141 ctggctgtct tatcaactcc cgacatggct ctcagaccaa tccaaatccc taaaaaaatc
    13201 agaacaagga tggtggtcaa gatcaaactc tcgaaatata aagaaaatag ttgcagtagc
    13261 atgatttctc tcatttctat cttttttaaa gagtaaactc agctagtcca actaactgag
    13321 ttttccttta tctattatat caaatataag tccgtttgta actagcgaag aattcttttg
    13381 tccgctcttc tttaggggtg tggataatct catccggagt tccagactct atgattttcc
    13441 ccttatctaa gaagagaatt ttatccgcaa cttgggctac aaaggacatg tcatgactga
    13501 ccaaaatcat ggtctgacct gacttagcag catctgcaat agacttttct acttcaccga
    13561 ccaattctgg gtcaagggct gaagttggtt cgtctaagag caaaacatct ggtttcatag
    13621 caagcgcacg cgctagggca acccgttgct tctgtccacc tgataaatgg cgaggataat
    13681 ggttttcacg gtccgaaagc ccaaccttag ccaactcttc cttggcaatc ttagtcgctt
    13741 cttggtcaga taatttcttg acaacaacca agccttcttt cacattatca agtgctgttc
    13801 ggcgttcaaa caaattaaac tgttggaaaa ccatagacaa cttacgacgt agggcaagga
    13861 tttcttcttg agtgatttta gaaaaatcaa ctgaaaaacc atcaatctga atagagccac
    13921 tgtcaggtgt ttcaagataa ttgagactgc gaagaaaggt tgattttcca gctcctgaag
    13981 aaccaatcaa ggctacaact tccccttttt gaatatccaa gtccagatga tccaagacag
    14041 tctgtcctga aaaggatttg cttaaattcg aaatcttaat cattaacgaa ggtctccttt
    14101 cacatctgtt tgcactgtat caggtgcaga aatagccatt tttctctcga tgaaacgacc
    14161 gaggctttca attccgatat tgactaccca ataaacaagg gcaacggaga tgaagcgttc
    14221 aaaatagcga taatcagctc cacctagaat ctgagcttgg gcaaagactt ccacaacacc
    14281 cgcactaaaa gctagagatg ttcccttggt caaaccgatg agggaattaa tcaaggttgg
    14341 agtagctacc accgctgcat taggaataat cactcgtcga taaacttgcg ctcgggtcat
    14401 acccagactg cgtgccgcct caatctcacc aggattaact gagagaatgg ctgcacgaat
    14461 ggtttcacta gcataagctg cctcattaaa ggcaaaggcg acaatcgcaa aagctgcagc
    14521 tggaatcgca ttgatattga gaccagttcc ccattgctga ttgagggctt tcaaagccaa
    14581 agggattccg tagtaggtca acatgagttg caccaaaatc ggtgtccctt ttaagaaact
    14641 aacaaagaag gcctgcaagg gatataaaat cttgacacga ttgatcttca caatggcaaa
    14701 aagaagcgcc aaaaccaagc caaaaagggc accaccaatt gtcaacataa ttgttgttgg
    14761 aagttgttgg acaattctag ggattccatc aaagaccgaa cgtaggctaa acagcttgcc
    14821 atccggaatc aattgcatca agttttggta ccaatctgat gctaaaatcg ttgtaacatt
    14881 cataaaaaca tcctcttctg ataatgattc attctaccat gcttctgccg tcaatgaaat
    14941 tatttgctac ggtcagatac agactttgtc tacctactag tttatcatac tttgaaacag
    15001 ggaagttata tattttatct atcaaagaga tagataaaaa ctatttcagt cccagttctt
    15061 cataagattt tcgataaccg atttgcttaa cagttccatt ttctactaaa atgggccgtt
    15121 ttaacaacat accgtcactt gctagcaact cagccgcttc ttggtttgac aaacttccta
    15181 ccttatcttt tagccctaat tcacggtatt tgataccact ggtgttgaaa aattgcttca
    15241 attcaaatcc tgaggtttct agccaattca aaatgacttc ttggctaggt gtttcttcca
    15301 cgatatggac ggctttatag tccacaccta attgatttaa ttcttgtttt gcttttttac
    15361 aagttgaaca tttggggtat tcgataaatt ctaacatgtg cttctccttc tatttgttta
    15421 tatctttaaa atctacgcct tcatgctcca agagccaagc tttcttttcc actcctgcag
    15481 catagcctgt cagacgcttg cctgctccca acacacgatg acaaggtact aggatagacc
    15541 aaggattgcg tcccactgct ccaccaattg cttgagcaga agccacttgc aggtcttgag
    15601 caatttgtcc ataggtcact gtctgaccat aaggaatgcc ctgtaaatag tcccaaactc
    15661 tcttttcaaa attcgttccg attggcgcca agagcaagtt ggataaatcc tgaggcttgc
    15721 ctttaaagta atcatctaag caagcaataa ctgggtctaa aataggatga ctaacaactt
    15781 cttctatcgt ttcatctcct agtcccctct caaaatgctt ctgctcctga acccaaattc
    15841 catacaaata atggtcatca gctacaagtg atagaatacc aattggtgag gagtagagga
    15901 tttttacata cttcttttgc attatttctt taatttttga taggccaagc gttcgccatc
    15961 tactggcacc ttaccaactt gtttaaaacc aagtttttca aaaatatgtt gcataacctt
    16021 gttttcagca tgcgtatctg agcgaaaatc aagataatca aaaccttcaa tcaagccctc
    16081 taagaaggtt tgagcaactc cttttccctg cacatctgct gccacagcaa tacggtgaaa
    16141 gactagatac tctgactctc cagcttgcca gtttccctca taaatagctt cataggcctc
    16201 ctctggactc ttggtcacag cagcataggc tagcagttct ccctcttcca aggctacgta
    16261 ggcttgccct gagatgatat catcgataat aacatctgca tttggatagc cattttgcca
    16321 ctggttacta ccagcatctg ctaaacattt tttggcatcc tctatcacct gcatgatggc
    16381 acctacttca tttggaaaag ctaaacgaat ttccatcttt tttcctcatt tctgactagt
    16441 ttctcccatc atagcataat ttaagtcttt ctacaagcag ttaaaacttg actttgtatt
    16501 tttgttattt tataatctag ttatcaaaac tatataaaaa ggagttgaaa atgaaaacta
    16561 ccttttccta cccaaaatgg gcagaaattc caaacattga cctctatctg gaccaggttt
    16621 tgctctatgt caatcaggtc tgcgccccta tctctcctaa taaagacaag ggcctaacag
    16681 catctatggt caacaattat gtgaaaaatg gttacctgac aaagcctgac aaaaaaaaat
    16741 accaacgcca acagattgcc cgtttgattg ctatcacaac cctcaagtct gtattttcta
    16801 ttcaagaaat agcccagaca cttaatactc tacaaactca agcaagttca gaccaactct
    16861 acgatgcttt tgtggactac atgaaccaag gaattaaccc agctaaccct attatccaaa
    16921 ccagctgcca aaccattaaa ctctatcatc aaactctaga cttaatcgat catactcaag
    16981 aggaggtaat ccaatgaaca ctagtcttaa actcagcaaa caactcagtt ttggagagga
    17041 gattgctaat agcgtgaccc atgctgtagg tgcagtcatc atgcttatct tgctgcctat
    17101 ttcatccatc tatagttatg aagcacacgg atttttatcc tctatcggcg tttccatttt
    17161 cgtcatcagt ctctttctca tgttcctatc atccaccatt tatcactcta tggcctatgg
    17221 ttcgacccac aaatatgttt tgcgaatcat tgaccattct atgatttacg ttgccattgc
    17281 cggctcatac acgcccgttg tcttgacctt gatgaataac tggtttggct atctgattat
    17341 tgtcatccaa tggggaacga ccatctttgg tattctctat aaaatctttg ctaaaaaggt
    17401 caatgagaaa tttagccttg ctctttacct gattatgggc tggttggttc tggctatcat
    17461 tcctgccatt atcagtcaaa cgacacccgt tttctggagt ctcatggtaa ctggcggact
    17521 ctgttataca gttggagctg gattttatgc caagaaaaaa ccttatttcc acatgatttg
    17581 gcatctcttt atcctagctg cgtccgcact ccaatacatc gctattgttt attacatgta
    17641 aaaaagttga gaagttcaat ctcaactttt ttctttacac atattgataa agtactggtg
    17701 caagcgcaca tcatcagtca attctggatg aaaagaactt accaacatat ttttttcttg
    17761 ggctgcaaca atttgattgt tcactgttgc tagaatttct acaccctcac caacactact
    17821 gataatcgga ccacggataa aggtcattgg aatcttgcca actcccttac attctgcttc
    17881 cgtgtagaaa cttcctaatt ggcgcccata agcattacgc tcgaccacca tatccatagt
    17941 tcctagatga ctctctttct gagaagtgat ttccttagcc agcaaaatta agcccgcaca
    18001 ggtcccaaac actggtaagc cagatagaat ggcttctcgg atgggaagta gcatgttctg
    18061 gtcacgtaag agcttgccca tggttgtaga ctcaccacca ggcaaaatca aacccgacaa
    18121 gtcactctga tcttgctgaa aatcatctag atttctgagt tctacactct cgacacctaa
    18181 ttgatctagc acttttgcat gttctgcaaa ggccccttgc aaggccaata ttccgatttt
    18241 catctatttt cctcgttcag ccatgagaat ttggatttca ttttcattaa taccaaccat
    18301 ggcttctcct aaatcttcag agatttgagc taggatttga ggattacgga agttagtcac
    18361 agccttaaca atggcactcg ctcgtttaac aggatctcct gacttgaaaa tacctgaacc
    18421 gacaaagacc ccctctgccc ctagttgcat cattaacgca gcatctgctg gcgttgcaac
    18481 acctccagca gcgaaattta caactggcaa ttttccatgt tcatgaacat attggaccaa
    18541 ttctacaggg acttgcaaat ccttggcagc aacataaagc tcgtcctcac gtaagttttg
    18601 aatgcggcga atttcctgat tcatcatacg catatgacga acagcttgga cgatatcccc
    18661 tgtccctggt tctcctttgg tacgaatcat ggaagcacct tcagcgatac gacgcaaggc
    18721 ttcacccaaa tccttagcac cacagacaaa aggaacttgg aattctttct tgtccacatg
    18781 gaaacggtca tcagctggag atagaacttc actctcgtcg atataatcaa tttcaatagc
    18841 ctctaaaatc tgagcttcaa caaaatgccc gattctgacc ttagccatta ctggaatact
    18901 aaccgcttct tggatttcct taatcatctt tgggtcgctc atgcgggaaa ctcctccagc
    18961 tgcacgaata tcagccggaa ttcgttccaa ggccatcaca gctgccgcac cagcagcttc
    19021 tgcgatacga gcctgttcag gattctgcac atccataata acaccaccct tgagcatctg
    19081 tgccaagttt ttatttagtt cataacgatt ttcagtcatt tgttttatcc tcatcatttg
    19141 tattggtagc taccttttca ttttaagtca gaacagaatg aagcacaaga taaaaaaact
    19201 ataattgtat ggggacaaat tagctaaaaa ctatctgacc ttaacttaag gccagatagc
    19261 tcattcattt ttatttttca gccgtaaggg cagccattgt gatgtagttg tatggtttgt
    19321 tgaagtgtgg caagaagaag aggtctgtca atgccaattt atcaattgtc acatgctctt
    19381 ggatagcaag tgagaacatg tggattccca tgctaattgc aatatcatgt gaaaccattt
    19441 gggcaccaag aatttcacgg ctatctttgt caaagacaat cttaattgct acttcatggt
    19501 tgtcatgttt catgaattct ggtttttgaa gatcgttaaa gcctgtttca gttgcgttgt
    19561 aaccagcagc tttcgctttt tcaagagtca aaccagttga aaccatgtga agaccgtaga
    19621 ttgagatacc atttgaacct tgaacaccga ttccttccaa ttcatgtcca caagcattgt
    19681 aggcaccaac gataccagtg cgaacagcat ttgaagcaag agcgatatag cttgtatctt
    19741 tacgagcatt gtcataaaca gtcgcacagt caccaacagc gtaaacgcct gggatagatg
    19801 tttcttgttt cttgtctaca aggaaggcac cgttgcggaa gagttcgatc ttaccatctg
    19861 caagggctgt gtttggacgg aaaccaactg caaggataac catatccacg tcaaagcttt
    19921 ctttgtcagt aatcaagcgt tcaactttac cgtcaccttc gattgcttta acagtttgac
    19981 ctagagccaa gcggatgttg tgatcttcca agttcttcgc catcatttgt gtgaagtctt
    20041 tgtcatagta accgttcaag acagtatcaa cgatatcaac aaggacaact tcttttccaa
    20101 gacgttcaaa ggcttcagca agttcaacac cgatgtaacc accaccaaca acggcgatac
    20161 ggtcgaggtg ttggctcttg tcagaaagtt tattgataac ttcttcagca ttttggtaca
    20221 atttcacgaa ttgtacgttt tcaagagttg ctttaaattc gcggtttcct ttaacaattt
    20281 caacaccttc gattggtggc aagattggtg tagaacctgt agcgaaaatc aatttttcgt
    20341 atgattcttt gtgctctttt ccttcaactt ccgctgtaac tactttgtta tcatagtcga
    20401 ttgaaagaac aggtgagttc atgtaaactt tagcaccttt agcttccaat ttttctttat
    20461 cagaatagaa caagccttca gcaccgtcaa tttgttcacc aatccaaaga gccattccac
    20521 atcctaggaa agagatgtta gagttttggt caaatacaac aatttcgttc tcatttccaa
    20581 aattatccaa catggtattg atacatgctg taccagcgtg gttagcaccg actacaacga
    20641 ttttactcat aaaaatttcc tgccttcatt ctaaatttac cttactagta taccatttac
    20701 cgttagcgtt tacaaggggg gtactattat ttcagcattt tttatcaaaa ataattcccc
    20761 atttatcctg ttttcaagcc tcatgaattt tatgagcata tttcttgact ttttccaaat
    20821 tttgtttgtg aaaattctaa ctttatggta ttataataac atgaaaatga aatgtaaggg
    20881 cttcaattta gataattatt ttatattaca acttattttc tataagagaa aggagttggt
    20941 agcttgactc ttcgttcaca ttctgaacgg ctaatgggga ctactatcac tatttcatta
    21001 gtggatgagc aagccgatat ctttctccaa aaatcctttg acttgctcaa agagcttgaa
    21061 taccgcttca acgccaatag tcaagaatct gagttgatgg aaatcaatta tcaagcagga
    21121 atatcccccg tcacggttca tccagacctg tttgagctga tttcacttgg gttagagcat
    21181 agcctagcgc tctctagcca cctcaatatc agcattggtc ccttaattca aacctggcgt
    21241 atcggttttt cagatgccaa ggtcgcccag cctcaagaaa ttgaatcggt gctgcctcta
    21301 atcaatcctc atggtatcga gttagattct tctacttcta ctgtgttttt aaaacagaaa
    21361 ggaatgaaga tcgatctagg ttgtttagcc aaaggataca gtgcggataa ggttgcccaa
    21421 tttcttagga aagagggggt gacttctgcc ttgatcaatc tgggagggaa tatcctgacc
    21481 attggaaaaa atcaggcaag aggggataac ccatggcaaa tcgggattca agacccagcc
    21541 aatccgaggg gaaatcattt aatgaccatc cctgttgtca ataaatctgt cgtgacttca
    21601 ggcatttatg aacgtcacct gaccgtcgat ggacaagatt accatcacat ttttgacagt
    21661 caaacaggat atcctgttga aacggaacta gcgagtctaa caatcatctc tgataaatca
    21721 gtcgatggcg aaatctggac gactcgactc tttggagaaa gacctgcttc tatcctctgg
    21781 caagtcgaaa gtttggaggg catcgaagtc atcctcatcg ataaagaagg ccacctaagc
    21841 tgttcttcag gaattcctac tctatagaga caactgtttc aatggaattt taaaattgta
    21901 ttatgtaaaa agagaaagga aatctcatgt taaaacttat tgctattgtt ggaacaaatt
    21961 caaaacgttc tacaaaccgt caattgcttc aatacatgca aaaacacttt gctgacaaag
    22021 ctgaaattga gcttgttgaa atcaaggcca ttcctgtctt caacaaacca gctgacaagc
    22081 aagtacctgc tgaaatattg gaaattgctg ctaaaatcga agaggcagat ggcgttatta
    22141 tcggtactcc tgagtatgat cactctattc cagctgtttt gatgagcgct cttgcttggt
    22201 tgtcttatgg tatttaccca cttttgaaca aaccaatcat gattacaggt gcttcttacg
    22261 gtacgcttgg ttcatctcgt gcccaattgc aacttcgtca aatcttgaat gctcctgaaa
    22321 tcaaggcaaa tgttcttcca gatgaattct tgctctcaca ctctcttcaa gcatttaacc
    22381 caagtggcga cttggttgac cttgatgtta tcaagaaatt ggatgccatc tttgatgact
    22441 tccgtatctt tgtaaaaatc acagaaaaat tacgtaatgc acaagaatta cttcgcaaag
    22501 atgctgaaga ctttgactgg gaaaatttgt aagataggag accaaaaaga atgaaatttg
    22561 ttggacttgt tggatcaaac tacgatcaat catataaccg taagctcttg gaatttatcc
    22621 gtcgctactt caaactcaaa tttgaattag aagttcttga aattgacgaa gttccaatgt
    22681 ttaaccaaga tgaaaaatgg gatgaaagtt tccaattacg tttcttgtat aacaagatta
    22741 cacgtgcaga tggtgttatc attgctactc ctgagcataa ccacactatc tcagcttcac
    22801 tcaaatctgt acttgaatgg ctttcatacg aagttcatcc atttgaaaac aagcctgtta
    22861 tgattgtggg tgcatcatac tatgaccaag gaacatcacg tgctcaagtt caccttcgta
    22921 aaatccttga tgctccaggt gttaatgcct acacgcttcc aggtaacgaa ttccttcttg
    22981 gtaaagctaa ggaagctttt gataacaacg gaaatatcac caacgaaggc actgttaaat
    23041 tccttgaaac ttgcttagat aactttgtta aatacgtagg agtcgtttcg aaattgaaaa
    23101 aaccaaaacc aatcgaatca gaagacttgg attgtggaaa accaatcgct acaaccatca
    23161 cagaagttga ccctgacgat ccagaatggg tagaaaaagt tgcagcaatc actggtgctg
    23221 tttctggtga tacctatgtc aaattggacc acggtatcct aacagttaac caaattgata
    23281 tgttcttgaa agctatgcca tttgaattga catacgctga cgacaacaac caattcctct
    23341 actacaacaa cgctcaccaa gatccagaca ctatgttcgc taaacgtgta ccacctcaat
    23401 caggtagccg tatgtcgact gttcatggtt ctcttccacc agcacgtatg aagaacgtag
    23461 agtgggttat cggaacactt cgcaacggaa accaagaata cgtccgtacg atcgttccag
    23521 gttctcctgc aggtgttatc aacactcaca actaccaagc aatgtactat cctgatggat
    23581 catacgctgg tatcaatgaa atcgtcttta acttccaacc atggcttgac tggtacctaa
    23641 aagagactgg tcaacgtttg gtgggtggta gcggaccatt tgctcctgct gccggaggtc
    23701 atggagacgc cgatgctact tctggcgctt ctgattcagg ggatgctgga ggccacggtg
    23761 gtgacgcaga cgctacagcc ggtgcaagtt actaatgata gtttttagga accattatgg
    23821 ttcctttttt agcgaaaaaa gactagcaaa cacaaactgc tagtctcttt gttatcgttt
    23881 catctatctt tgttaaaaga aagaatacat atactcaatg aaaatcaaag agcaaactag
    23941 gaagctagcc gcaggctgta cttaagtacg gcaaggtgaa gctgacgtgg tttgaatttg
    24001 attttcgaag agtattatta tgaatttgga tcatcaagac tacggccatg taatcctttt
    24061 tcacgttgta cttggcgtag tttttctggt gtaacatcgt ttccttcttc gtccacaatt
    24121 ttgattcctt caatgtggtg acgaacagcg cggcgataac cttcgatgta ctcctcacgt
    24181 agtttggctt gttccacttt ttcttctgat gttaagcctt ctgttttttt ctttttagca
    24241 agctcattga tacgagcaat ttttttcgga tccatttctt ctcctttgta ataagataaa
    24301 gtctgtttat caaattttat ttagtgttaa tttggttaaa acaagcaaac ttagctgctt
    24361 tcttggttag ttgtgacaag attgccaaac gattttgacg gacagcctga tcttcagcca
    24421 ttaccatagt attttcaaag aaagcatcaa tgactgggct aagcgcaaag agttgtttca
    24481 attgctgact tgcaggtcct gataaaacga gtgtttctac tgcttctgcc aaagcttttt
    24541 cttggtcatt ctcaaatagt gctgaatcaa ctgtagcaac cccttctgcc ttctcagcca
    24601 ggttaaaggc acgagaaagt gattcaacag atggtttaaa atcttcttcc ttgcttactt
    24661 ctacgagagc acttgctgct tccaacatat ctgccacaac aaagtttgaa cctgcaagaa
    24721 ctgcttcttt gatatctttt ggagtagagc ccatcatctt atcaacacga gccttgataa
    24781 agtccataac ctctgcttta ttttcataag tcaaactgtc aaatttcaat gcataaaggc
    24841 tatcaatcag ctcatccata gcaatgtgcc aaccaaaggc atccaagata cgaaccacac
    24901 cttgagttgc acgacgaagg gcataagggt cattagaacc tgatggaatc aatcctactg
    24961 agaagaaact caaaatcgta tccaatttgt ctgcaatggc tagaactgcg ccgaccttgc
    25021 tctctggaag ttctccttca gctgatgtag gcatgtagtg ttcacgaata gcagctgcca
    25081 ccgctggagt ttcaccagca agaagggtgt atttttcacc cataattcct tggagttcgt
    25141 caaattcacc aaccatacct gtcaacaagt caaacttgta aatggctgct gcacgagcaa
    25201 ggtcaactgt ttcatccact gacaaaccag ctttttctgc caaaagtaca gtgatttgac
    25261 ccgtacgaat catgtgttca cgaagggaac caatcttctc atggaaggtg acattgttta
    25321 atttttcaac aagatctgaa atcaccaatt tttggtcttc acgccagaag aattctccgt
    25381 cttccaagcg ggctaccaag actttttcat ttcctttgat gacatttttc aaacgctctg
    25441 cgtttccgtt acgaacagaa atgaagtttg gcaagagttt tccatcttga tcacgaacaa
    25501 caaagtaacg ctggtgttcc ttcatagaag tcaccaagac ttcttctgga acttcaaggt
    25561 atttagcatc aaaacttccc atgaaggcag ttgggtattc aaccaaattc aagacttcat
    25621 tcagcaaatc cgcatcaatt tcgatacgta caccatgttt tgcctcaatt tccttgattt
    25681 ggtcaacaat catttgctca cgttcacatg gatctgcgat tacaaactgc ttacgaaggt
    25741 cttcttcata gctcaatgct gactgaattt tggtttcttt ccccaagaaa cgatggccac
    25801 ggctcacacg acttcccttg atatcaagga aatccaagtc aaactcttgc tcatccaaga
    25861 gaacagttaa agtgtgaaca gggcggatgt attcaaagct atttccagcc cagtgcatgc
    25921 tgacagggaa agtcaatgac ttcaagacat ctacaacacc aggaacaatg gcttcaactg
    25981 attgaccaac ttcttcctta gtgacataga catattcttc acccttgatt tcacggaatt
    26041 cgatatcttc aacagtcaaa cctttcccac ggacaaatcc ttgagctgct ttggtgaagt
    26101 ttccatcact atccaaggca attttctttg ctggtccctt gaaatcttct gtcaaatcag
    26161 actgtttgtc tgataaacca gtcacacgaa cagccaaacg acgtggtgtt gagaaggttt
    26221 gaatggcttc aaaagacagg cggttttcct tgaggaaggc tgccattttt tcgcctagtt
    26281 gtttttcact tggtgtgaca acataggctg gtaattcttc aagaccgagt tctactaata
    26341 agttttttgt catgtttttt cctttacatt ttcttcaatc ttttttgata tgcaccttag
    26401 gtactgggga cgtcgctaac taactctgtg agtctgtatg gaaatccaat gctaaattta
    26461 tcaagatttc caacaatctc atcaaagtgg atttagctga ctgatttttg aacctaaggt
    26521 ttcaaaaatc cccacataac agtacggcgg tgcatatccc tctagcaagt cttcgacttg
    26581 cctctaacga ttttagagta cagtattact cactattctg cgtcttctgc taaaagttta
    26641 actcgtgttt cttcatccaa aagtgggtaa cctaggcgtt tgcgttctgc aacaaaggtt
    26701 ttggctacaa cacgggccaa gttacggata cgagcgatat agcctgcacg ctctgttaca
    26761 gatacggcac cacgcgcgtc aagcagatta aaggtatgtg aacatttgag aacatagtca
    26821 taggcagggt gtaccaagcc ttcttctaat gcacgaccag cttctttttc aaacttatca
    26881 aagttttcaa gcaacatttc ttggtccgaa atttcaaatg aatattttga gtgctcatac
    26941 tcaggctgga taaagatttc tccgtatttt acaccattag cccactcgat atcatagaca
    27001 gagtctactt cttgaatgta agaagccaag cgctccaaac cataggtaac ttccgcagtc
    27061 acagggccag ttgccaatcc accgacttgt tggaaataag tgaactgagt gatttccatt
    27121 ccgtcaagcc aaacttccca accaagacca gctgaaccag ttgatgggtt ttcccagttg
    27181 tcctcaacaa aacgaatatc gtgctccaaa ggattgattc ccaatttttc caaagactca
    27241 aggtaaagtt cttggatatt tgatggagaa ggcttcatga ccacctggaa ttggtggtgt
    27301 tggtagagac ggttagggtt ttccccataa cgaccgtcag caggacgacg tgatggctct
    27361 acataagctg cattccatgg ctcaggtccg atagcacgaa ggaaagtgta aggactcatt
    27421 gttcccgcac ctttttcatt atcataagcc tgcataagca tacaaccttg gtcattccaa
    27481 aattgttgca aagtcaaaat aatttcttga aatgttaatt tcttagacat tgaatactcc
    27541 ttaataaaaa ataattactt gcgacacgag tctgcctcgt cgat
//
LOCUS       DAVLGK010000030        27481 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLGK010000030 DAVLGK010000000
VERSION     DAVLGK010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.030"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            71..1849
                     /locus_tag="VXE01_001407"
     CDS             71..1849
                     /locus_tag="VXE01_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV0750301.1"
                     /translation="MSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIY
                     WNKKTNKYKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIG
                     RSAMVTKLLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYP
                     ELEPSKVGTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGK
                     TYLAKEIAKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKD
                     FCQKAKETQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSG
                     VPGWSLPSKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKF
                     VFIIDEINRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIG
                     TMNDIDRSVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIEN
                     VQELNSHYHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAF
                     ELTNNEQKDQAVADDNEGDENDDADY"
     gene            1836..3152
                     /locus_tag="VXE01_001408"
     CDS             1836..3152
                     /locus_tag="VXE01_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV0750302.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            3327..4313
                     /locus_tag="VXE01_001409"
     CDS             3327..4313
                     /locus_tag="VXE01_001409"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV0750303.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENIAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            4377..4448
                     /locus_tag="VXE01_001410"
     tRNA            4377..4448
                     /locus_tag="VXE01_001410"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4410..4412,aa:Arg,seq:ccg)
     gene            4631..5329
                     /locus_tag="VXE01_001411"
     CDS             4631..5329
                     /locus_tag="VXE01_001411"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV0750304.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRETILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            5320..8859
                     /gene="smc"
                     /locus_tag="VXE01_001412"
     CDS             5320..8859
                     /gene="smc"
                     /locus_tag="VXE01_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV0750305.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKDRTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDEMARLIESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQERLATIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            8856..9650
                     /locus_tag="VXE01_001413"
     CDS             8856..9650
                     /locus_tag="VXE01_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0750306.1"
                     /translation="MTIKLVATDMDGTFLDENGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYI
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            9650..10468
                     /locus_tag="VXE01_001414"
     CDS             9650..10468
                     /locus_tag="VXE01_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0750307.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYADVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGINQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            10472..11761
                     /gene="ftsY"
                     /locus_tag="VXE01_001415"
     CDS             10472..11761
                     /gene="ftsY"
                     /locus_tag="VXE01_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV0750308.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTIEENNSEVLEPERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(11805..13292)
                     /locus_tag="VXE01_001416"
     CDS             complement(11805..13292)
                     /locus_tag="VXE01_001416"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV0750309.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(13441..14181)
                     /locus_tag="VXE01_001417"
     CDS             complement(13441..14181)
                     /locus_tag="VXE01_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0750310.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(14181..16346)
                     /locus_tag="VXE01_001418"
     CDS             complement(14181..16346)
                     /locus_tag="VXE01_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0750311.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQSQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            16516..17469
                     /locus_tag="VXE01_001419"
     CDS             16516..17469
                     /locus_tag="VXE01_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0750312.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLEFIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            17546..19534
                     /gene="uvrB"
                     /locus_tag="VXE01_001420"
     CDS             17546..19534
                     /gene="uvrB"
                     /locus_tag="VXE01_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV0750313.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDVNSLNKQE
                     RKDLVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            19557..20024
                     /locus_tag="VXE01_001421"
     CDS             19557..20024
                     /locus_tag="VXE01_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0750314.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENGESFVESVIREIYEETGLTIQNPQLVGVKNWPLDTGGRYIVFCYRATEFSGTLQS
                     SEEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(20021..20107)
                     /locus_tag="VXE01_001422"
                     /pseudo
     CDS             complement(20021..20107)
                     /locus_tag="VXE01_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
     gene            20338..21315
                     /locus_tag="VXE01_001423"
     CDS             20338..21315
                     /locus_tag="VXE01_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0750315.1"
                     /translation="MTTIKQVAEEAGVSKSTVSRYISKKGYVGDDAREKIKNAIKKLN
                     YTPNVLAQSLKTKKNQMVGLLLPDISNPFFPRLVRGAESYLKDKGYRIMVGTISDHDS
                     LEEYINLLLKTNAAGIITTLDFTKEFPNLTLPVVVVDRISKDTGYGVFSDNQLGGRLA
                     AKAIWNAGAEQVMIIKVLDDKAENIVERFEASLNYLRNKNLEICIEESETFDFEKIQK
                     EAKENLKRNPNIDSIIAPSDIHAIAYIHEILAIGKKIPDDIQIIGYDDIVLSQFIYPS
                     LSTIHQSSYKMGEQAAKLIYNMANKFSIDEAKIKLPVRYIERNTLRRKK"
     gene            21312..22223
                     /gene="rbsK"
                     /locus_tag="VXE01_001424"
     CDS             21312..22223
                     /gene="rbsK"
                     /locus_tag="VXE01_001424"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HEV0750316.1"
                     /translation="MSKIVVVGSISMDLVMRTKRIPEGGETIFGDSFNIVPGGKGANQ
                     AVAIGRLSSVEDNIYIFGNVGEDIFSADLLSNLQNNDISTAYVGTVPQSTGVAQITLY
                     GGDNRIIYYPGANNLVKTNDWKNEWKLLSDASIVVLQNEIPHEANLSIAKFCQENQVK
                     VLYNPAPARETDKEMIPFCDFITPNEHECSELFPDKKLEEIIKIYPNKMIVTLGVEGS
                     IYYDGTAVKKIPAIKAEVVDTTGAGDTFNGAFAYAISKGKEMNVALSFATIASHLSVQ
                     RFGAQGGMPSLKEIKEHSGYEEIWDFK"
     gene            22198..22596
                     /gene="rbsD"
                     /locus_tag="VXE01_001425"
     CDS             22198..22596
                     /gene="rbsD"
                     /locus_tag="VXE01_001425"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HEV0750317.1"
                     /translation="MKKYGILNSNIAKLADDLGHMDWVCIGDLGLPVPKGVDKIDLAL
                     RKGSPSFLEVLKEYSDHVLIEKIFLAEEIKEQNTEQWQAVLDLLGSNIIIEYISHEEL
                     KAMNTKVKAVIRTGEDTPYSNIILQSGVII"
     gene            22610..24088
                     /locus_tag="VXE01_001426"
     CDS             22610..24088
                     /locus_tag="VXE01_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HEV0750318.1"
                     /translation="MKIEMKNISKSFGNNRVLESIDLVLNSGEVHALMGENGAGKSTL
                     MNILTGLFPATSGTIFIDGKEKTFSNPQEAERFGLSFIHQEMNTWPDMTVLDNLFLGR
                     EIKNSIGFLDKASMEKKAKEAFKRLNISIPLDAIIGQLSVGQQQMIEIAKCLLSEVSL
                     LIMDEPTAALTDRETETLFKVIEGLKSDGVGIVYISHRMEEIFKITDLITVMRDGFVI
                     DTKKTKLTNADELVQKMVGRELEDYYPEKKAEIGNIVFQAKNLSGNSFTDVSFYVRQG
                     EILGFSGLMGAGRTEIMRAIFGIDSLKSGQIIINEEELIIKNPFEAIKHGIGFLTEDR
                     KDEGLILDFSIKDNMTLPSTRDFVKNGIFDNKTSDIFVQRLIDRLQIKSGYPDKEVGT
                     LSGGNQQKVVLAKWIGIAPKVLILDEPTRGVDVGAKREIYQLMNELAERGVPIIMVSS
                     DLPEVIGVSDRIMVMHEGRISGELTRQEATQEKVMQLATGGQ"
     gene            24090..25031
                     /gene="rbsC"
                     /locus_tag="VXE01_001427"
     CDS             24090..25031
                     /gene="rbsC"
                     /locus_tag="VXE01_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771495.1"
                     /note="functions to transport ribose at high affinity;
                     forms a complex with RbsA2C2B; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HEV0750319.1"
                     /translation="MKNTMKYMSELTTVIALIILMAVITIINSNFLTANNLLNLLLQV
                     TSNALIAFGMTFVILTGGIDLSVGSILALSSALTAGLLGSGMPVTLAILISLILGCIL
                     GMMNGLLISYGKLAPFIVTLATMTIFRGATLVYTNGNPITKGLSDTFLFQFLGQGYIV
                     GIPFPVIIMFIVFIVLYVLLHKTAFGKSVYAIGGNEKAAYISGVKLNKVKIIIYSISG
                     IMASISGLIITSRLSSAQPTAGASYEMDAIAAVVLGGTSLSGGKGRILGTLIGALIIG
                     VLNNGLNIIGVSAFWQQVVKGVVILIAVLIDRFKVVK"
     gene            25139..26104
                     /locus_tag="VXE01_001428"
     CDS             25139..26104
                     /locus_tag="VXE01_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEV0750320.1"
                     /translation="MKIIKKISIFALFVTFIFALVACGKTGLGNSSNDNKSTTQKSAK
                     ELKLGVSISTTNNPYFVAMKDGLEKAAGEKEVTLKIADAQDDAARQADDIQNFISQNV
                     DALLINPVDSDAIVTSIKAANNANIPVILIDRGSNGGEVLTTVASDNVEAGKMAAEFI
                     TKQLGEKAKTFELSGVPGASATVDRGKGFEQISKTNLDVLSSQSANFDRAKALNTAQN
                     MIQGNKEVQAIFAQNDEMALGAAQAVKAAGLSNVLIVGIDGQPDAHDAIAKGDITATI
                     AQQPAKMGEIAIQSAIDHYQGKKLEKETVSPIYLVTKDNVDQHNW"
     gene            26179..26322
                     /locus_tag="VXE01_001429"
                     /pseudo
     CDS             26179..26322
                     /locus_tag="VXE01_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            complement(26319..26834)
                     /locus_tag="VXE01_001430"
     CDS             complement(26319..26834)
                     /locus_tag="VXE01_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV0750321.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLTIVDNGGRVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(26846..27373)
                     /locus_tag="VXE01_001431"
     CDS             complement(26846..27373)
                     /locus_tag="VXE01_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0750322.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHIVFGTLGALYLRKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVVFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT         8755 a         4657 c         5943 g         8126 t
ORIGIN      
        1 tggtgaaaag tttaatgata aattaaaaga agagtttctc caggaatggc ctttggatag
       61 gattttaaca atgtcaatcg atgaatatgt aataggaaag ggacagcaaa ataagtcttt
      121 atgctacgct cttgagaagg gaaaatacaa aaatctattt cttggaattt ctggtggctc
      181 agcttcaaaa tttggtattt attggaataa aaaaacaaac aaatataaag atcaagctaa
      241 taatgagatt tcagagttgg atcagcgatt ttcaaaatta aaatcagatt tgtatgaaat
      301 tatcaaagaa ggtattcgtt ttaactttga aaatcctatt tttgatatga aaagatcaac
      361 aaatgaattt attggtcgtt ctgctatggt gacaaaatta ctttgtatct attctgaggg
      421 agatcctttc tttggtgtaa atattaatag tcagaaagaa ttttggaacc actttgtttc
      481 tcagacaaat caaggtggac cttatctgca aaatcataaa ataattgaac tggtgtccaa
      541 aacttatcct gagttggagc catcgaaagt aggaactatg ctttttgagt attctaagct
      601 ttttatggaa aataaggaag acaatagtac aatggattca tcaaacaatt ttcgtcatca
      661 attaactcaa tctctattaa agtctccaaa ccttatcctt cgtggtgctc ctggcacagg
      721 aaagacttat cttgctaaag aaattgccaa agaattaacg gatggcaacg aagaccaaat
      781 cggatttgta caatttcacc catcatatga ttatacggat tttgtagaag gtttaagacc
      841 agtatcaaat ggggatggag ctattgagtt taggctacag gacggtattt ttaaagattt
      901 ttgtcagaaa gcaaaagaaa cccaattgat tggaggacaa gataattttg atgaggcttg
      961 ggattcttac ttagaatata taaatgttgc tgaagaaaaa gaatatataa caaaaacatc
     1021 ttacttatct gttaatagta gacaaaattt gtcagtaaat tatgatagtg gtgttccagg
     1081 atggtcacta cctagcaaat atgtttacga gttgtataaa gataaaaatt ataataagca
     1141 agaatactac aaaagtggtg gaaaaactgt cctagaaaca ttgagaaaga gatttggttt
     1201 gaaagactat gtttccccaa cagaaattga tactgataag aaattcgtct tcatcatcga
     1261 tgaaatcaat cgtggggaga tttctaagat ttttggcgaa ctctttttct ctatcgaccc
     1321 tggctatcgt ggtgaaaaag gaagtgtttc tacccaatat gcaaatctac acgaaactga
     1381 tgaaaagttc tatatccccg aaaatgttta catcatcgga actatgaatg atattgatcg
     1441 ttcagtggat acctttgatt ttgctatgcg tcgtcgtttt cgttttgttg aagttactgc
     1501 cgagggtcaa gttggcatgt tggataaaga gctgaatatc catgcagaag aagcaaaaat
     1561 tcgtctaaga aacttgaacg ctgctatcga aaatgttcag gaattaaaca gtcattatca
     1621 tattggacca agttattttc ttaagttgaa ggatgtagat tttgactatg aattactctg
     1681 gtctgattat attaagcctc tcctagaaga ctacttgcga ggttcttatg atgaggttga
     1741 aactttggaa actttgaaaa aagcatttga actgacaaat aatgagcaaa aagatcaggc
     1801 agtagctgat gacaatgaag gtgatgaaaa cgatgatgcg gattactgat aatcaacaca
     1861 agattattaa agaaaaattt gttgaagaat atcctaaact aagcaatctt cttttagaca
     1921 gaaccttgga aagtctatcc caagatgaac gtattttcat ttttccaaat gatttgactc
     1981 atactcctga tttggataag gaccaaaaga tttttgaaac agtcaatcag aaaatcaaga
     2041 cagggaacgt gattggtttt cttggatatg gtcaggaaag attaacgatt tcctcacgat
     2101 tttctgatga gagtaatgac cattttttgc attatctctt aaacaaggtt cttcatatca
     2161 atctcactag tttagatgtt gctttgtctc gtgaagagag gctttatcaa cttttggtgt
     2221 atctctttcc caagtatcta caagctgcta ttcgaaaagg tctttataag gaatatcatc
     2281 gattttctca taacgacagt catgttaagg gagtgattga tgtaagaaac catctcaaga
     2341 aaaatcttcc tttcacggga aatattgcct acgcaacgag agagttcacc tatgataatc
     2401 ccctcatgca gttggtccgt cacactattg aatacattaa gaatcagaaa agcattggtc
     2461 aaggggtact agataatctc tcaactagtc gtgaaaacgt atctgaaatc gtgcgtgtaa
     2521 cgccctctta taaactagct gatcgtgcta agattattcg gggaaatcaa tctaaaccta
     2581 tacgtcatgc atactttcac gagtacagaa acttacaaga actttgtctg atgatcctaa
     2641 accaagaaaa gcacggttta gggtatcaag atcaaaaaat ctatggtatt ctctttgatg
     2701 ttgcctggct ttgggaagag tatgtttaca ccttgttgcc aaaaggtttt gtacatccca
     2761 gaaataagga taagacggat ggaatttcag tattttctgt tgggaaacga aaagtatatc
     2821 cagattttta tgacagagaa cgaaagattg ttctagatgc aaaatataaa aaactggaat
     2881 tgactgaaaa aggaatcaac cgtgaggact tattccagct gatttcctat tcttatattt
     2941 taaaagctga gaaggctgga cttgtttttc cgagcaagga caaggttatt gataatgaga
     3001 tgggaaacct agcaggttat ggagctttgt tgaagaaatg gtctatccaa attcctcaga
     3061 agtcttcatc ttatagtgca ttttgtaaaa tgatggaaaa ttcagaagaa aattttaaag
     3121 cgattattga tgaagaagtg gggagaaaat aatttcctct ctttctttta tttttaacac
     3181 aagtaaaacc cgaacaatat atttcaattc ataaaataat ttgacaaaaa ctgtactttg
     3241 gtttataata aattaaggaa acgtcggaaa aggcgtagtg atgcaagagc ataggtaggt
     3301 cattacaaaa gaaacgagac atcgatatgt taaatgaatt tccaattttt gattacgaag
     3361 atattcaatt gattccaaat aaatgtgtca ttaaaagccg tgcagaagcg gatacaagtg
     3421 tcactttagg aaatcacacc tttaaactac ctgttgtgcc agcgaatatg cagacgattt
     3481 tggatgaaaa tatagcagag caactggcta aaggtggtta cttctacatt atgcaccgtt
     3541 ttgatgaggc aggacgcatt ccttttatta aacgaatgca cgatcaaggg ctcattgctt
     3601 ccatatctgt cggtgttaag gactatgagt atgattttgt tagccagctc aaggctgatg
     3661 ctcctgagta tatcactatt gatattgctc atggtcatgc ggatagcgtg atttctatga
     3721 ttcaacacat caagaaagaa ttgccagata cctttgtcat tgctggaaat gtgggaacac
     3781 cagaagctgt gcgtgaattg gaaaatgctg gtgcggatgc tactaaggtc ggaatcggtc
     3841 ctggtaaggt ttgtatcaca aaggttaaga ctggttttgg tacaggtggt tggcagttgg
     3901 ctgctctacg ctggtgtgcc aaggctgcgc gtaaaccgat tatcgctgat ggaggaattc
     3961 gtactcacgg tgatattgcc aagtctatcc gcttcggtgc tagcatgatc atgattggtt
     4021 ccctctttgc aggacacatt gaaagtccag ggaaaacgat tgaagtcgat ggtgaacagt
     4081 tcaaagaata ttatggttca gcctcacaat atcaaaaagg tgcttacaaa aatgtggaag
     4141 gcaaacgtat cttgcttcct gctaaaggtc atctgcaaga cactttaact gagatggaac
     4201 aagaccttca aagtgctatt tcttatgcag gtggacgtca ggttgctgac cttaaacacg
     4261 ttgattatgt gatcgtgaaa aactccatct ggaatgggga tgcttcccac taagacgggg
     4321 tctttgacca aaaaacttgt tattagagca aatttctgtt ataataaaac aagtttccac
     4381 ccttagtgta atggatatca cgtaagattc cggttcttga gatgggggtt cgattccctc
     4441 agggtggatg taaacatcct aaaaagcctt taatagggct tttttcttta tcctgaccca
     4501 aatttgccgc taaaactgag aatctctgtc taaagaattc ccaaatgctt tccagtcccg
     4561 ttttagagtg actcaggggg ctttttttga tataataaaa aggactatta tcagttagaa
     4621 agaggttggt atgaaagaat tacaaactgt actaaagaat cattttgcaa tcgaatttgc
     4681 agacaaaaat ttactggaaa ctgcctttac tcatacgagt tatgccaatg agcaccgcct
     4741 cttaaaaatt tcacacaatg aacgcttgga atttttagga gacgctgttc tacagttatt
     4801 gatttcagaa tatctatata aaaaatatcc taaaaagcct gaaggtgacc tatcaaaact
     4861 ccgtgctatg attgtccgtg aggagagttt agctggtttt gcgcgtgatt gccagtttga
     4921 ccagtttatc aagttgggta aaggggaaga aaaatcaggt ggtcgcaatc gtgaaaccat
     4981 tcttggtgat gcctttgaag cctttcttgg tgcccttctt ttggataagg atgtggccaa
     5041 ggtcaaggaa tttatctacc aagttatgat tcctaaggta gaagcaggcg aatttgagat
     5101 gattacagac tataaaaccc atctccaaga gttacttcag gtcaatggtg atgtggctat
     5161 tcgttatcag gtgatttctg aaacagggcc tgctcacgat aaggtctttg atgtagaagt
     5221 tcttgttgaa ggtaagagca tcggtcaagg ccaaggtcgt tctaagaaat tagcagagca
     5281 ggaagctgcc aaaaatgccg ttgagaaggg gctggattca tgtatttaaa ggaaatcgaa
     5341 attcaggggt tcaagtcttt tgctgataag accaaggtcg tttttgacca aggtgtgacg
     5401 gcagttgttg gacccaatgg atctggaaag tccaatatta cagaaagtct gcgttgggct
     5461 ttgggggagt ctagtgtcaa gagtctccgt gggggcaaga tgccggatgt catctttgct
     5521 ggaacagaaa gtcgcaaacc gctcaattat gcttctgtag ttgtgactct ggataatcat
     5581 gacggattta tcaaggatgc aggtcaagaa atcagggtgg aacgccatat ctatcgtagt
     5641 ggagatagcg aatacaagat tgacggcaag aaagtccgtc tgcgtgatat tcatgacctc
     5701 ttcttggata ctggattggg acgagattcc ttctctatca tttcccaagg gaaggttgag
     5761 gagattttta attctaagcc tgaggaacgc cgagctattt ttgaagaagc tgcaggagtt
     5821 ttaaaataca agactcgcag aaaagaaacc gagagtaaac tgcagcaaac tcaggataat
     5881 ctggaccgct tagaggacat tatctacgag ttggataatc aaatcaagcc tcttgagaag
     5941 caagctgaga atgcccgtaa gtttttagac ttggaaggac aacgtaaggc tatttattta
     6001 gatgttctgg ttgctcaaat caaggaaaat aaggctgaac tagagtcgac agaagaagag
     6061 ttggctcagg ttcaagaact cttgatgagt tattaccaaa agcgtgaaaa attagaagaa
     6121 gaaaatcaaa ctcttaaaaa gcaacgccaa gatttacagg ctgaaatggc caaagaccaa
     6181 ggcagtttga tggacttgac tagtctgatt agtgatttag aaagaaaatt agccctatcg
     6241 aaactggagt ccgagcaagt ggccttgaat caacaggagg cacaagcccg tttggctgct
     6301 ttggaggata agagaaattc actcagcaaa gaaaagtctg ataaagaaag ctctttagct
     6361 ctgttagagg gaaatctagt ccaaaataat caaaaactca atcgtttaga agctgaattg
     6421 ctggctttct cagacgatcc tgatcagatg attgagctct tacgtgaacg ctttgtagct
     6481 cttttacaag aagaagcgga tgtctcaaac cagttgaccc gtattgagaa tgagttggaa
     6541 aatagtcgtc agctttctca aaaacaagca gatcaactag aaaagctgaa agagcaatta
     6601 gctatagcta aagagaaggc tagtcagcaa aaggaagagc ttgaaactgc caaggagcag
     6661 gttcagaaat tattggctga ctaccaagct attgccaagg agcaagagga gcagaaaact
     6721 tcctatcaag ctcaacaaag ccaactcttt gaccgtctgg ataatctcaa aaacaagcag
     6781 gccagagctc aaagtttgga aaatatcctg agaaatcata gtaactttta tgcaggtgtt
     6841 aagagtgttc tccaagaaaa agatcgccta ggtgggatta ttggtgcagt cagtgagcat
     6901 ctgacctttg atgtttatta tcaaactgcc ctagagattg ccttaggggc aagtagccag
     6961 catatcatcg tagaagatga agagtcggca accaaagcta ttgatttcct taaacgaaac
     7021 agagccggtc gtgcaacctt ccttccgttg acaacaatca aggatcgtac gatttctagc
     7081 cagaatcaag atgctatcgc tgtaagtcca ggtttccttg ggatggcaga tgagttggtg
     7141 acttttgata ctagactgga agccattttc aagaatttgc tagctacaac ggctatcttt
     7201 gataccgtgg agcatgcgcg tgcagcagcg cgccaggttc gttatcaggt tcgtatggtg
     7261 acattggacg gaacagagct gcgcacaggt ggttcttatg caggtggagc taatcgccag
     7321 aataacagta ttttcatcaa gccagaactg gagcaattac aaaaagaaat tgctgcagat
     7381 gaagcaagct tgggttcaga agaagcggct ttgaagacct tgcaagatga gatggccaga
     7441 ttgatcgagt cattagaagc tattaaatct caaggagagc aggcacgcat tcaggagcaa
     7501 ggcttgttcc tcgcttatca gcaaactagt cagcaagttg aagaactgga aactctttgg
     7561 aaactccaag aagaggaaat agatcgtctt tccgagggag attggcaagc agacaaggaa
     7621 aaatgccaag aacgccttgc tactatcgcc agtgacaagc aaaatctgga agctgagatt
     7681 gaagagatta agtctaacaa aaatgccatc caagaacgct atcaaaactt gcaggaagag
     7741 ctagcgcaag ctcgtttgct taagacagaa ctgcaagggc aaaaacgtta tgaagttgct
     7801 gatattgaac gcttaggcaa ggaattggac aatcttaata tcgaacaaga agaaatccag
     7861 cgcatgctcc aagaaaaagt tgacaatctt gagaaggttg atacagaatt gctcagtcaa
     7921 caggcggaag aatccaaaac tcagaaaaca aatctccaac aaggtttgat tcgcaagcag
     7981 tttgagttgg atgatataga aggtcaactg gatgatattg ccagtcactt ggatcaagct
     8041 cgccagcaga atgaggagtg gattcgcaag caaacacgtg ctgaagccaa gaaagaaaag
     8101 gtcagcgagc gcttgcgcca tctacaaaat caattaacag accagtacca gattagctat
     8161 actgaagcac tagaaaaggc acatgaattg gaaaacctca atctggcaga gcaagaggtg
     8221 caggatttag agaaggctat tcgctcattg ggacctgtca acttggaagc tattgaccag
     8281 tacgaagaag ttcacaaccg tctggacttt ctaaatagtc agcgagatga tattttgtca
     8341 gcgaaaaatc tgctccttga aaccattaca gagatgaatg atgaggtcaa ggaacgcttt
     8401 aaatcaacct ttgaagctat tcgtgagtcc tttaaagtga ccttcaagca gatgtttggc
     8461 ggaggtcagg cagacttgat attgactgag ggcgaccttt taacagctgg tgtggagatt
     8521 tctgttcaac ctccaggtaa gaaaatccag tcgcttaacc tcatgagtgg tggtgaaaaa
     8581 gctctatcgg ctcttgcctt gcttttctcc attattcgtg tcaagaccat tccttttgtc
     8641 atcttggatg aggtggaagc tgcgctggat gaagccaatg ttaaacgttt tggggattac
     8701 ctcaaccgct ttgacaagga cagccagttt atcgtcgtaa cccaccgtaa gggaaccatg
     8761 gcagcggctg attccatcta tggagtgacc atgcaagaat cgggtgtttc aaagattgtt
     8821 tcagttaagt taaaagattt agaaagtatt gaaggatgac aattaaacta gtagcaacgg
     8881 atatggacgg aaccttccta gatgagaatg ggcgctttga tatggaccgc ctcaagtctc
     8941 tcttggtttc ctacaaggaa aaagggattt actttgcggt ggcttcgggt cggggatttc
     9001 tgtctctgga aaaattattt gctggtgttc gtgatgacat tattttcatc gcggaaaatg
     9061 gcagtttggt agagtatcaa ggtcaggact tgtatgaagc gactatgtct cgtgactttt
     9121 atctggcaac ttttgaaaag ctgaaaacgt caccttatat agatatcaat aaactgctct
     9181 tgacgggtaa gaagggttca tatgttctag atacggttga tgagacctat ttgaaagtga
     9241 gtcagcatta taatgaaaat atccaaaaag tagcgagttt ggaagatatc acagatgaca
     9301 ttttcaaatt tacaaccaac ttcacagaag aaacgctaga agctggtgaa gcttgggtca
     9361 atgataatgt ccctggtgtc aaggctatga caactggctt tgaatctatt gatattgttc
     9421 tggactatgt cgataagggt gtagctattg ttgaattagc taaaaaactt ggcatcacaa
     9481 tggatcaggt catggctttt ggagacaatc ttaatgactt acatatgatg caggttgtgg
     9541 gacatcctgt agctcctgaa aatgcacgac cagagatttt agaattagca aagactgtga
     9601 ttggtcacca taaggaccag tcggttatag cttatatgga gggcttataa tggcagatat
     9661 aaaattaatc gcattggact tggacggtac cttgctgact actgataaaa ggctgacgga
     9721 tcgcaccaag gcaactttga aagctgcgcg tgatcgtggt atcaaggtcg tattgacaac
     9781 tggtcgtccc ttaaaagcca tggacttctt tctccatgag ttagggactg acggtcagga
     9841 agatgagtat accattactt ttaatggtgg tttggttcag aaaaatacag gtgaaatcct
     9901 tgataaaaca gtcttttcat atgctgatgt ggcacgtttg tatgaagaaa cagagaaatt
     9961 atcactgcca cttgatgcca tctcagaagg aacagtttat caaatccaat cggaccaaga
    10021 aagtctttat gccaaattca atccagcttt gacttttgtt ccagttgact ttgaagacct
    10081 gtctagtcaa atgacctaca acaaatgcgt gactgccttt gctcaagaac ccttggatgc
    10141 agccattcag aagatttctc cagaattgtt tgaccaatat gaaatcttta aatcacgtga
    10201 aatgttgcta gagtggtcac caaagaatgt tcataaagca acaggtttgg caaaactaat
    10261 cagccatctt ggaatcaacc aaagccaagt tatggcctgt ggtgacgagg ccaatgacct
    10321 ttctatgatt gaatgggcag gtcttggtgt tgctatgcaa aacgctgttc ctgaagtaaa
    10381 ggcagccgca aatgtagtaa cgccgatgac caacgatgag gaagctgtcg cctgggctat
    10441 cgaagaatat gtgctaaagg agaactaaga tatgggattg tttgaccgtc tattcggaaa
    10501 aaaagaagaa cctaaaatcg aagaagttgt aaaagaagct ctggaaaatc ttgatttgtc
    10561 tgaagatgtt gatcctacct tcacagaagt tgaggaagtt cctcaggaag aagcagaggt
    10621 tgaaattgtt gaacaagctg tgttccaaga ggaggaaatc caagacacag ttgaagaaag
    10681 tcaggattca gagccagctg taggggtttc tcaagaagaa atagaagaat taccaaactc
    10741 agaagaatta ccagaggaag agaagcttga gcacgaagga actatagaag aaaataattc
    10801 tgaagttctt gaaccagaaa ggcctcaaac agaagaaact gttcaggaaa aatatgaccg
    10861 cagtctcaag aagactcgta cgggcttcgg tgctcgcttg aacgccttct ttgctaactt
    10921 ccgctctgtt gacgaagaat ttttcgagga actggaagaa ctgctgatta tgagtgatgt
    10981 tggtgtccaa gtcgcttcta acttaacgga ggaactacgt tacgaagcca agcttgaaaa
    11041 tgccaagaaa cctgatgcac ttcgtcgtgt catcattgag aaattggttg agctttatga
    11101 aaaggatggt agctacgatg aaagcatcca cttccaagat aacttgacag ttatgctctt
    11161 tgttggtgtg aatggtgttg ggaaaacaac ttctattgga aaactagccc accgctacaa
    11221 acgaactggt aagaaggtca tgctggttgc agcagatacc ttccgtgcgg gtgcagtagc
    11281 tcagctagct gaatggggcc gacgagtaga tgttccagta gtaactggac ctgaaaaagc
    11341 tgatccagcc agcgtggtct ttgatggtat ggaacgtgcc gtggctgaag gtatcgatat
    11401 tctcatgatt gatactgctg gtcgtctgca aaataaggat aaccttatgg ctgagttgga
    11461 aaagattggt cgtattatca aacgtgttgt gccagaagca ccacatgaaa ccttcttggc
    11521 acttgatgca tcaacaggtc aaaatgccct agtacaggcc aaagaatttt cgaaaatcac
    11581 acctttaacg ggaattgttt tgactaagat tgatggaact gctcgaggag gtgtggttct
    11641 agccattcgt gaagaactca atattcctgt aaaattgatt ggttttggtg aaaaaatcga
    11701 tgatattgga gagtttaact cagaaaactt tatgaaaggt ctcttggaag gcttaatcta
    11761 atcagaagca aaaatcctgc aaggtacaaa cttgcaggat ttttttattc gaaacgacca
    11821 tcttgacgat aggcgatatc tggttgccaa gtccatttgg catcgaattt ttcaagtagg
    11881 tcaaagctgg cttgaggtcc catgcttcca gctttatagt catgaagtgg ggcaccattt
    11941 tcggcccaga gctcttcaat acggtcaatc aacttccatg acgcaccaac ctcatcccag
    12001 tggctaaagt tagttgagtt gttatttagg acatcataaa tcaatttctc gtatggttct
    12061 ggagaagcac cagttgcagt cgcgtctgta cgataatcaa gtgagttagg agccaagtta
    12121 aattcttctc ctacttgctt cccatttagg ctaagagaga agccttctgt tggttgaata
    12181 tagatggtca aaatatttgg agcaagtggt tctccaaaga tagaatccat ttgtttaaag
    12241 acgatgttga catgagttcc tttttcagtc agtcgtttac ctgtacggaa aaagaaagga
    12301 acaccacgga atcgatcgct gtctacaaag aaggcaccag atgtaaaggt ttcagttgtt
    12361 gattctggat tcacatttgg ttcgctacga taagagatgt atttcatgcc atcaatctta
    12421 ccagagcggt attgtccacg gataaagtgt tctttgagtt cttcatcagt tggatgatag
    12481 aggtttttaa agaccttaat cttttcagca cgaatctcgt cttttgtgaa gcttgctggt
    12541 ttgtccatgg cgaggagcga aagaagttgt agagtgtggt tttggaccat gtcacggagg
    12601 gcaccggatt ggtcatagta gccaccacgt tcttctacac ccaagcgctc cgcaaaggta
    12661 atttgaacat tgtcgataaa atccttgttc caaacgtttt caaaaatcaa gtttgcaaag
    12721 cgaactgcaa agatgctttg gatcatttcc ttaccaagat aatggtcaat acggaaaatt
    12781 tgttcttcgt caaatgttgc taggagttcg tcattcaact tacttgcagt tgcgtaatct
    12841 gtaccaaatg gtttttcaac gatcaagcgc tcaaaacctt tgccatcgac aatgttttca
    12901 gatttgaggt gtttggcaat ggttccaaag aactgaggtg ccatagacaa gaagaagagc
    12961 ttattgtgtt cagcttggta tttttcatta agctcagctt gtaattgacg caaagcaata
    13021 taatgttccg aatcattgac atcatggctt tgatagtaga agtggctagc aaattcttgg
    13081 gcttgctcgg tactatctgc caaatcaagg atggactcga caactacaga ttcaaaatat
    13141 tccttactcc aaggtctacg ggcagttcca ataacggcaa agtgcttgga aagattgccg
    13201 gatttatata gtctaaaaag ggaagggtag agcttgcgtt tagccaggtc tccactcgca
    13261 ccgaaaattg taacaataac cttagatgac atctagctac ctaatttcta tttttattcc
    13321 tagtcttgct aggtatgagg aaacctcatt tcataaactt aattctaaca taattttccg
    13381 aaaaatcaaa aattccaata cgaggtagaa aaactgcaag gaaatcctta cagtttgagt
    13441 ttagacgttt aagaccttat ctaagaactc tttcagacga gggtgttgtg ggttatcaaa
    13501 gatttggtca ggtgttccgt cttcaaggaa ctcgccatct gcagtaaaga taacgcggtt
    13561 ggcaacctga cgagcaaatc ccatctcatg ggttacgata atcatggtca tgccttgctc
    13621 agccaattcc ttcataacgt taagtacgtc tccaaccatc tcagggtcaa gggcagaagt
    13681 tggttcatcg aagagcatga tgtctggatt cattgctagg ccacgagcga tggccacacg
    13741 ttgtttttga ccacctgata ggctatctgg attggcatta gctttatctg ctagtccaac
    13801 cttttcaagc aactccattc ccaattcctc agcttcttcc ttagtcatca acttgtgctc
    13861 aataggagca aaggtgatgt tgtccaatac agacatatga gggaagaggt tgaagtgttg
    13921 gaataccatg ccgatatttt cacggacgtg gtcaacattg gttgtttttt cagttaaatc
    13981 atagccgttc acagtgatgt gaccgctagt gacttcttct aaaagattga ggctacggag
    14041 gaaagttgac ttaccagaac ctgaaggacc gatgatacaa acaacatctc cttcatagaa
    14101 cttagtcgta attcctttta ggacttcatt ttttccatag tgcttgtgta aatcatttac
    14161 atcaattttt aattttgcca ttaacgaatc ctcttttcta agcgtttcgc tagtctagtc
    14221 aaaagtgtga taattacaag atagaagata gcaaggattg catacatctt gaaactttgg
    14281 tagttacgag caatgataat cttaccagtt tggaagagtt caaccaaacc gatagcagat
    14341 acgatagttg tatctttaag agcgataacg aattggttga caaagtttgg caacatcaat
    14401 ttagttgctt gtggcaagat aatcttacgc atggtttttc cataagagat acccaagctt
    14461 cggctggctt ccatttggcc aactggaacg gcctgaatac caccacgaac gatttcagcg
    14521 atataagcag ccgcattgag tgagagggca attgttccag ctacaaagtc gttaattggg
    14581 ctttgttggc ctgtgataga ctcgatgaag tttggaattc cccagaagat gaaggctgca
    14641 agaatcatca atggaatacc acgaataacg tcaacgaaaa tctcagagat gacgcgaaga
    14701 gatttgtatg ggctaacgct aaacataccg aagataattc cgatgacaat ggcaatagca
    14761 aatgagataa gagctagagc aagagtgata ccaagaccgc taaggagttg tttgtagttg
    14821 ttttgaagca agccccagag cgttgtttcg tcaacagtac ttgttgaagc agttgaagat
    14881 tcgctagcta ggtatttgtc aagaatcttt tggaattcac cgtttgcttt aaggtttgca
    14941 agtccgttgt tgaacatttc aatcagttct ggatttgctc cttttttaac ggcaaaggct
    15001 gtttcaccga ttggagttcc agagattgga gttttcaatt tttgactttg gctgatagaa
    15061 tatttgagaa caggttcatc atccataacg gcatcaatgg caccagtgtt taaactgtca
    15121 tacattgaag aaccatcagc aaaggttttg attttgtaac cgtatttgct ttgattttct
    15181 gttaggaagg tttgagaagc agttccgttt ttaacaccga ctgtctttcc ttttagatct
    15241 tcataagaag caatattgct tgattctttg acaccaagaa tggtattagc agtgtagtat
    15301 gattctgaga agtcaaaagt tgccttacga gcatctgtga cagacatacc agcaatgata
    15361 ccatcggctt gaccagcttg gacagcactg atagcagcat caaaaccagg gttggtgatt
    15421 tcaatttcaa aaccttggtc tttagcgatt gccttaatca attccatatc aataccagtg
    15481 tattggttgc ttgaattttg gaaaacaaaa ggtgcaaaag aagaatcgct ggcaatgata
    15541 tatttagcct taacaggaat agcttttaat cctgcgagag tagttgtagt tggcactgct
    15601 gaagatgatg aagcagtcca tttcttgata attttatcaa gactaccatc ttttttcatt
    15661 tcagacaagg cttggttaaa ttcagtaacc aggtgctcgt atttacttcc ttttttcaca
    15721 ccgaaagcaa aacttcctac agcttcacca tccatttcaa tatggaggtc ttgaccttgg
    15781 ttaatggcat attcgataac aggtttgtca tccatcatgg catcgatggc accagcactc
    15841 aagctgttgt tcattaaatc accagtgtca aatgttttaa tagtaaagcc gtatttatct
    15901 ttgattgttt caaggaaacg ttgagcggca gttccgtttt taacaccaac ggttttgcca
    15961 gttaattggt cgtacttgct aattttgtgt gactttgtag tagcaatgac aacttttgta
    16021 tcatagtaag tatcagacat ggtgaagact ttttcacgtt ctttagtctt tgtcatccct
    16081 gccatgatag cgtcggcttg cccagcttga accgcattga ctgctgcgtc aaatccagga
    16141 taggacatct gaatgttcca gcctttaatc tcagcgactt tgttaataat gtcaacatca
    16201 attcctttat aagtttgatc tgaatcttta aactcaaaag gtgcataggc ggtatcagaa
    16261 acaatcttaa tcgtttctgc tttggcaata cctaatgaga aaattgggaa taaaattagc
    16321 aaaaatgcta gaaatttttt cttcattttt agtctccttt tccgaatatt ctctcattat
    16381 atcagaaaaa gtaaaaaaag gcaaattttt atatttttcg tgtcagaaaa tataacattg
    16441 attttttcct ttccttgaat tgctattaaa aagtgctata ataatagtat atatagaaga
    16501 aaagaggacg gggatatgaa gaacaaaaga atatttaaag acttccaagc ttcaaaaatg
    16561 agtttaaaca tttacacaag ccccttgtta gcctttgttt ttgtcttcat aggagagttt
    16621 gtggctttta ctttgtatgg tattggcttg ttagctctca tcggacttgc tagaaatttt
    16681 ggagaggctg gtcaaaatct tgcaagctac ttgcagacct tgcatcagag cttgacggat
    16741 aaaacaagtg actttcgttt aattttagga ttactggcct ttggttttat tcttaacact
    16801 gtgttcagat ggacaagaaa agttgagaaa agacctattc gaaccttggg attttataga
    16861 gagaatttcc tcagcaatct tctgaaagga tttagtctag gtctggcact ttttcttctg
    16921 accttgttag gtttggtggt cttaggtcaa tatcgtttgg aattcattca cttgaatcct
    16981 tattctcttg cctttgtcgt ctttactatc ccattttgga ttttacaggg gacagcagaa
    17041 gaagtggtgg cccgtgcttg gctacttcct caattggcct caagaaccaa tctaaaacta
    17101 gctattctta tatctagcct gttctttacc ctgcttcata tgggcaattc tggcctcacc
    17161 cctctatctc tagtaaatct ctttttattc ggagttgcca tggctcttta ccttctcaaa
    17221 actgatacag tttggggtgt tgcaggtatt catggtgctt ggaattttgc tcagggtaat
    17281 ctctttggga ttttagttag tggtcaaccg tcaggaacgt ctctgatgac ctttttacca
    17341 caaggcaatc aagattggct atcaggtggt tcttttggca tagaaggttc cattatgaca
    17401 agtctggtat tactactgct gattgtctat cttgctaata aattaaagaa agaaaatgaa
    17461 aggatgtgac ttcggtccat ccttttcttc gtgaaaatac tataagtatg ctaaaatagg
    17521 aatagcacat ggagagagga ttcttatgat caatcacatt acagataatc aatttaaact
    17581 agtatcaaaa tatcaaccat caggagatca accccaagct atcgagcagt tggtggataa
    17641 cattgagggg ggagaaaaag cacagattct gatgggggcg actggaacag ggaagaccta
    17701 tactatgagt caggtcattt ctaaagtcaa taaaccaact ctggttattg cccacaataa
    17761 aactctggct ggtcagctct atggggagtt taaggaattt ttccctgaaa atgcagttga
    17821 gtatttcgta tcctactatg attattacca gccagaggcc tatgtccctt ctagcgatac
    17881 ctatattgag aaggatagtt ctgtcaatga cgagattgac aagcttcgcc actcagctac
    17941 ctcagccctt ttggagcgta atgatgttat tgtcgtggcc tcagtctctt gtatctatgg
    18001 tttgggttcg cccaaggaat acgctgatag tgtcgttagt ctccgtcctg gtctagagat
    18061 ttctcgtgat aaactcttga atgacttggt cgatattcag tttgaacgca atgatattga
    18121 tttccaacgc ggaagatttc gcgttcgtgg ggatgtggta gagattttcc cagcttcccg
    18181 agatgaacat gcctttcgag tagaattttt tggagacgaa attgaccgta ttcgtgaagt
    18241 tgaggctctg acaggtcagg tgttgggaga agtggatcat ttagcgattt tcccagcgac
    18301 acactttgtg accaatgacg accacatgga agttgccatt gcaaagattc aggccgagtt
    18361 ggaagaacaa ttagctgtct ttgaaaagga aggtaaactg cttgaagccc agcgtttgaa
    18421 acagcggaca gagtatgata tcgaaatgtt gcgtgagatg ggctatacca acggggttga
    18481 gaactattca cgacacatgg atggacggag cgaaggagag cctccttata cgctcttaga
    18541 tttcttccca gatgattttt taattatgat tgacgagagt cacatgacca tggggcaaat
    18601 caagggcatg tacaatggag accgttcgcg taaagaaatg ctggttaatt atggtttccg
    18661 tttgccgtct gctttggaca atcgtcctct ccgtcgggag gagtttgaga gtcacgttca
    18721 tcagattgtt tacgtttcag cgacacctgg tgactatgaa aatgaacaga ccgagacagt
    18781 gattgagcaa atcattcgtc caacgggact cttggatcca gaggtggaag tccgtccgac
    18841 tatgggacag attgatgacc tcttgggtga aatcaatgcc cgcgttgaaa aaaatgagcg
    18901 tacctttatc acaactttga ccaagaaaat ggcagaggac ttgaccgact acttcaagga
    18961 aatgggtatc aaggtcaagt acatgcactc ggatatcaag accttggaac ggacggagat
    19021 tatccgtgac ctgcgcttgg gtgtctttga tgtcttggtc ggaattaacc tgctccgtga
    19081 aggaattgac gttcctgaag tgagcctcgt agctattctc gatgctgaca aggaaggttt
    19141 cctacgtaac gagcgtggac tcattcagac tattggtcgt gctgcccgta acagtgaagg
    19201 tcatgtcatc atgtatgctg acacggttac ccagtctatg caacgtgcta tcgatgaaac
    19261 tgcccgccgt cggaaaatcc agatggccta taatgaagaa catggtatcg ttccacaaac
    19321 cattaagaaa gaaatccgtg acctgattgc cgtaactaag gcagttgcta aggaagaaga
    19381 caaggaagtt gatgttaata gcctcaacaa acaagaacgt aaagatcttg ttaagaaact
    19441 cgaaaaacaa atgcaagaag ccgtcgaagt gcttgacttt gaactagcag cacagattcg
    19501 tgatatgatg ttggaagtca aggcgttaga ttagaataat atctaaagga gaaaatatgt
    19561 cccgttccca attaacgatt ttaacaaaca tttgtctgat tgaagacctc gaaactcagc
    19621 gcgtggtgat gcagtatcgc gcccctgaaa acaatcgctg gtctggttat gcctttccag
    19681 gaggccatgt agaaaatggc gaatctttcg tagagtctgt cattcgtgaa atctatgaag
    19741 agacaggatt gactatccaa aatccacaac tggtaggcgt taaaaattgg cctctggata
    19801 caggcgggcg ctacattgtc ttttgttata gggcgaccga gttttctgga actcttcaat
    19861 cttcagaaga gggagaagtt tcttgggtgc aaaaagacca gattccaaac ttggatctgg
    19921 cctatgatat gttacccttg atggagatga tggaagctcc tgacaaatca gagtttttct
    19981 accctcgccg tacagaagat gattgggaga agaaaatctt ctagtctttt actaaataac
    20041 ctagctgatc caagacctcc tcaatatagt ggaggtcttg ttgtgtttcg tatctaatag
    20101 tatagtagat tgaaataaga tataaacaaa tcaatcagga aagtaaaatt aatttctaga
    20161 aatattttag cagtcacgac gtactattct ggtttcaatc aattataata gaagattagt
    20221 aaaaacatgt gtactctgaa ataaatttaa aatatttcta aaaaagtatt gacaaaataa
    20281 aagaaaacgc ttactatata aataagggaa cggttccaca ataaaaaagg aggagtgatg
    20341 actacaataa aacaggttgc tgaagaagct ggagtatcaa agtcaacagt ttcaagatat
    20401 atttcgaaaa aaggctatgt cggagatgat gcgagagaaa agataaaaaa tgctatcaag
    20461 aaattaaatt acacaccaaa tgtattagca caatctttaa aaactaaaaa aaatcaaatg
    20521 gtaggactct tattgccaga tatttctaat cccttcttcc caagattggt tcgaggagcc
    20581 gaatcatatt tgaaagataa aggttatagg attatggttg gtactatttc agatcatgat
    20641 tcgttagaag aatatataaa ccttttgtta aaaacaaatg cagctggtat tataacaaca
    20701 cttgacttta caaaggaatt tccaaatcta acattacctg ttgttgtggt tgaccggatt
    20761 agtaaagata caggctatgg tgttttttct gataatcagt tgggtggacg tttggctgct
    20821 aaagcaattt ggaatgctgg cgctgagcag gttatgatca tcaaagtttt agatgataaa
    20881 gctgagaata ttgtggaacg atttgaagca agtttaaact acttgaggaa taaaaattta
    20941 gaaatttgta ttgaagaaag tgaaacgttt gactttgaaa aaattcaaaa agaagctaaa
    21001 gagaatctaa aaagaaatcc aaatattgat agtattatag caccttctga tattcatgcg
    21061 atagcttata ttcatgaaat tttagcaatt gggaaaaaaa ttccagatga tattcaaatc
    21121 attggttatg atgatattgt acttagtcaa tttatttatc cttctttatc aactatccac
    21181 caatcatcat ataaaatggg agaacaggct gcaaagctaa tctataatat ggcaaataag
    21241 ttctctatag atgaagctaa aattaaactc cctgttaggt acatagaaag aaatacatta
    21301 aggagaaaga aatgagtaaa attgttgttg ttggaagcat ttcaatggac ttagttatga
    21361 gaacaaaaag gattccagaa ggaggtgaaa cgatttttgg cgattcattt aatatagttc
    21421 caggtggaaa aggtgcaaat caagctgtag ctattggtag attatccagt gttgaagata
    21481 atatttacat atttgggaac gtaggagaag atattttttc agcagattta ttaagtaatc
    21541 tgcaaaataa tgatatttct acagcatatg tgggaacggt accacagtct acaggagttg
    21601 cacaaattac tttatatgga ggtgataata ggattattta ttatcccgga gctaataatt
    21661 tagttaaaac aaatgattgg aaaaatgagt ggaaattact tagtgatgca agtattgttg
    21721 tattacagaa tgaaatacca catgaagcca acttatctat agctaaattt tgccaagaaa
    21781 atcaagttaa ggttctttac aatcctgcac cagctagaga aacagacaaa gagatgattc
    21841 ctttttgtga ttttattact cctaatgagc atgaatgttc agagcttttt ccagataaga
    21901 aattagagga aattattaaa atttatccta ataaaatgat tgtaacatta ggagttgaag
    21961 gctctattta ttatgatggg acagcagtta agaaaattcc tgctataaaa gctgaagtag
    22021 ttgatactac aggagcagga gatacgttta atggtgcttt tgcttatgct atctcaaaag
    22081 gaaaagagat gaatgttgca ttgtcctttg caacgattgc ttcacatctt tctgttcaaa
    22141 gatttggagc acaaggaggt atgcctagtt tgaaagaaat aaaggagcat tcaggatatg
    22201 aagaaatatg ggattttaaa tagtaatata gcaaaactag ctgatgattt aggtcatatg
    22261 gattgggttt gtatcggaga tttgggattg ccagtcccaa aaggtgttga taaaattgat
    22321 ttagcattaa gaaaaggtag tccaagtttt ttagaagttt taaaagaata ttcagatcat
    22381 gtacttattg aaaaaatttt cttagcagaa gaaattaaag aacaaaacac agaacagtgg
    22441 caagcagttt tagacctttt aggatcgaat ataattattg aatatattag tcacgaagaa
    22501 ttgaaagcta tgaatactaa agtaaaggca gttattcgca ctggggaaga tacaccatat
    22561 tcgaatataa tcttgcaatc aggagttatt atttagaagg gggttaccta tgaaaattga
    22621 aatgaagaac atttcaaaat cttttgggaa taatcgtgtt ttagaaagta ttgatttggt
    22681 tcttaattca ggagaagttc atgctttaat gggagaaaat ggtgcaggca agtcaacctt
    22741 aatgaatatt ttaactggtc tttttccagc tacttcagga actattttta ttgatggaaa
    22801 agaaaaaaca ttttctaatc ctcaagaagc agaacggttt ggactgagtt ttattcatca
    22861 agaaatgaat acttggccag atatgactgt acttgataat ctttttttag gaagagaaat
    22921 taaaaattcg attggctttc tagataaagc tagtatggaa aagaaagcta aagaagcatt
    22981 taaacgtctt aatatctcta ttcctctcga tgcaattatt ggtcaattat cagttggaca
    23041 acaacaaatg atagaaatag caaaatgttt attatcagaa gtttccttgt taattatgga
    23101 tgaacctaca gcagctttaa ctgatcgtga aactgaaaca cttttcaaag tgatagaagg
    23161 attaaaatct gatggtgtag gtattgtgta tatttcacat cgcatggaag aaatctttaa
    23221 gatcacagat cttataactg taatgagaga tgggtttgta attgatacca agaaaacgaa
    23281 gttaactaat gcggatgaat tagttcaaaa gatggtaggt cgtgaattag aagattatta
    23341 tccagaaaaa aaggctgaga ttgggaatat tgtttttcaa gctaagaatc tttctggtaa
    23401 ttcttttacg gatgtttctt tctatgtacg tcaaggggaa attcttggtt tttctggttt
    23461 gatgggggct ggtcgtactg aaataatgcg agcaattttt ggaattgatt ctttaaaatc
    23521 tggtcaaatt ataataaacg aagaagaact gataattaaa aatccttttg aagcaattaa
    23581 gcatggaatt ggtttcttaa cagaagatcg taaagatgag ggattgattt tagatttttc
    23641 tatcaaagat aatatgactt tacctagtac tcgtgatttt gttaaaaatg gcatttttga
    23701 taataaaaca agtgatatat ttgtacaacg cttaattgat aggttacaaa ttaaatcagg
    23761 ttatccagat aaagaagttg ggacactttc tggtggtaat caacagaaag tagttttagc
    23821 aaaatggata ggtattgcac caaaagtact gattttagat gagccaactc gtggggtaga
    23881 tgttggagct aagcgtgaaa tttaccaatt aatgaatgaa ttggctgaac gaggtgtacc
    23941 gattattatg gtctcttcag atttaccaga agtgattgga gtcagtgatc gtattatggt
    24001 catgcatgaa ggtagaatta gtggagaatt aacacgtcaa gaagctacac aagaaaaagt
    24061 tatgcaacta gctacaggag gacaatagtg tgaaaaatac tatgaagtat atgtcagaat
    24121 tgacaacagt aatagcattg ataattttaa tggctgtcat cactattatc aattcaaatt
    24181 ttttaacagc aaataatctg ttaaatttac tattgcaagt aacatcaaat gcactgattg
    24241 cttttggaat gacctttgtt attctaacag gtggaattga tttatcagtt ggatcaattt
    24301 tagccttatc cagtgcgcta acagctggcc tattaggatc tggaatgcct gttacattag
    24361 caattctcat ctctttaatt ttgggttgca ttctaggtat gatgaatgga ttattgattt
    24421 cctacgggaa attagctcca tttatcgtca ctttagcgac tatgactatt tttaggggag
    24481 caacacttgt ttatacaaat ggaaatccta ttacaaaagg attaagtgat acattcttat
    24541 ttcaattttt ggggcaaggt tacatagtag gaattccatt tcctgtaatt attatgttta
    24601 ttgtatttat tgttttatat gttttacttc ataaaacagc atttggtaaa tctgtatatg
    24661 ctataggggg gaatgaaaaa gcagcatata tatcaggtgt aaaattaaat aaagtgaaaa
    24721 ttatcattta ttcaatatca ggtattatgg cttcaatttc tggattgatt ataacatcac
    24781 gcttaagttc tgctcaacca acagcaggtg ctagttatga aatggatgct attgcagctg
    24841 ttgttcttgg gggaacctct ttatctggag gtaaaggtcg tatattgggg actctaatag
    24901 gtgctttaat tattggagtt ttgaataatg gacttaatat tattggtgtt tcagcatttt
    24961 ggcaacaagt agtaaaagga gttgtaatct taattgctgt tttgattgat cgttttaaag
    25021 ttgtaaaata gtagaataat ttttcaagtt ttttggaaat agtaacaatt tattagatga
    25081 cgaacaatag tcgggatgga aactatccct gtagatatat attacgagga gtaataacat
    25141 gaaaattatt aaaaaaatta gcatttttgc tttgtttgta acatttattt ttgctttagt
    25201 agcttgtgga aaaactggtt taggaaattc atcaaatgat aataaatcta cgacacaaaa
    25261 gtcggcaaaa gaattaaaat taggagtttc tatttctact actaacaatc cttattttgt
    25321 ggctatgaaa gatggtcttg aaaaagctgc aggggaaaaa gaagtaactt tgaagatagc
    25381 agatgcacaa gatgatgctg ctagacaagc agatgatatt caaaatttta ttagtcaaaa
    25441 tgtagatgct ttgctaatta atccagttga ttctgatgca attgtgacat ctattaaagc
    25501 tgctaataat gcaaacattc cagtaatctt aattgaccgc ggtagtaatg gtggtgaagt
    25561 cttgacaact gttgcttctg ataatgtaga agcgggtaaa atggctgctg aatttattac
    25621 caagcaattg ggagaaaaag caaaaacttt tgaattatca ggggtcccag gcgcttctgc
    25681 aacagtagat agaggtaaag gatttgaaca aatttcaaag acaaatttag atgttctttc
    25741 tagtcaatct gctaattttg atcgtgcaaa agctttgaat acagcgcaaa atatgattca
    25801 aggaaacaaa gaagtacaag cgattttcgc acagaatgat gagatggcat tgggagctgc
    25861 acaagcagta aaagcagctg gtcttagcaa tgtattaatt gttggtatcg atggtcaacc
    25921 agatgcacat gatgctattg caaaaggtga tattactgcc actattgctc agcaaccagc
    25981 taagatgggt gaaatcgcca ttcaatcagc aattgatcat tatcaaggaa aaaaactaga
    26041 aaaagaaaca gtttctccaa tttatcttgt gactaaggat aatgttgatc aacataactg
    26101 gtgatatatt tttaataagt agatacttat tcatcttcat tcaatgtagt ttttaaatat
    26161 cattgctact atttgaactc ttgggtgcaa aaagaccaga ttccaaactt ggatctggcc
    26221 tatgatatgt tacccttgat ggatatgatg gaagctcctg acaaatctga atttttctac
    26281 cctcgccgta cagaagatga ttgggaaaag aaaattttct aatcctttac taaataacct
    26341 agctgatcca aggcctcctc gatatagtgg aggtcttgtt gtgtttcggc ttcgactagg
    26401 tggtaatgga tgccatctgt taattcagac agaggtctaa aatctgaatg ctcgacttgt
    26461 tctagaaaat gttgcacatc tctacgacaa gacagtttca gcaaggtttc aatttctcca
    26521 tagacaggat ggtcaatcaa agtgttttga acacgtccac cattatctac gatagtaagg
    26581 agttcctgac cgatttcttc aacttcatgt ttcactttga atagtttgtg aacataagga
    26641 ttggtatcaa tttgcttata gatgtagcca cgattagtgg ataggatagg agcgccatcg
    26701 gctcttaaaa ttgcaatgtc ttgtacaatg acctgacgtg tgacatgaaa atgttcagct
    26761 aaactttggc cattaagggc tttaggagct tctttcaaga gttggagcag ggcttgtttg
    26821 cgatcttttg tcatagttct tccttttaac ggcgttttcg aagcacttta tagacagcta
    26881 gtgctaatgt atagtctacc atactatgga taattgtgcc aaatccaact agcacaaaga
    26941 gaacataaaa catattttct acattggtac cagaagttgc gtaaaaaacg acacaggcta
    27001 atacttcagc aagtgcatga acaacagcca aaacaaagtt gaaaacccag gaagattttg
    27061 gtttatctag ggtatcgggg aattttcgta ggtaaagagc tcctagggta ccaaaaacga
    27121 tatgagagaa agctctaaaa acaataacca tgggatagcc agccatcaaa aatccaaaac
    27181 tagaagctag gatgacaaaa actgccatca agggcgacaa gaacatggct ataaaaatag
    27241 cgatgtggct ccccaaagta taggaagcag gtggaatgac aatcttgaaa ggcataacaa
    27301 ttggaatcaa aatcgcaata gccgttaaaa gggctgtcat tgtcataaat tgtgtctttt
    27361 tccgtgtatt cacaagaatc tcctttttaa ctgcatatac actagtatgg tacaataaac
    27421 cagacaataa agcaagaatt tacttgggtt tatagatcat tttttagtta aaagttatag
    27481 t
//
LOCUS       DAVLGK010000031        26646 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLGK010000031 DAVLGK010000000
VERSION     DAVLGK010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.031"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(136..903)
                     /locus_tag="VXE01_001432"
     CDS             complement(136..903)
                     /locus_tag="VXE01_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV0750323.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKHAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGSRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(900..1766)
                     /locus_tag="VXE01_001433"
     CDS             complement(900..1766)
                     /locus_tag="VXE01_001433"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV0750324.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(1803..3170)
                     /gene="accC"
                     /locus_tag="VXE01_001434"
     CDS             complement(1803..3170)
                     /gene="accC"
                     /locus_tag="VXE01_001434"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV0750325.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(3182..3604)
                     /gene="fabZ"
                     /locus_tag="VXE01_001435"
     CDS             complement(3182..3604)
                     /gene="fabZ"
                     /locus_tag="VXE01_001435"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV0750326.1"
                     /translation="MIDIQEIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKCRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(3601..4086)
                     /locus_tag="VXE01_001436"
     CDS             complement(3601..4086)
                     /locus_tag="VXE01_001436"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV0750327.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(4089..5324)
                     /gene="fabF"
                     /locus_tag="VXE01_001437"
     CDS             complement(4089..5324)
                     /gene="fabF"
                     /locus_tag="VXE01_001437"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV0750328.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(5346..6077)
                     /gene="fabG"
                     /locus_tag="VXE01_001438"
     CDS             complement(5346..6077)
                     /gene="fabG"
                     /locus_tag="VXE01_001438"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV0750329.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(6111..7031)
                     /gene="fabD"
                     /locus_tag="VXE01_001439"
     CDS             complement(6111..7031)
                     /gene="fabD"
                     /locus_tag="VXE01_001439"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV0750330.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(7024..7998)
                     /gene="fabK"
                     /locus_tag="VXE01_001440"
     CDS             complement(7024..7998)
                     /gene="fabK"
                     /locus_tag="VXE01_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV0750331.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(8117..8341)
                     /locus_tag="VXE01_001441"
     CDS             complement(8117..8341)
                     /locus_tag="VXE01_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0750332.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(8401..9375)
                     /locus_tag="VXE01_001442"
     CDS             complement(8401..9375)
                     /locus_tag="VXE01_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV0750333.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(9375..9809)
                     /locus_tag="VXE01_001443"
     CDS             complement(9375..9809)
                     /locus_tag="VXE01_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0750334.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(9903..10688)
                     /locus_tag="VXE01_001444"
     CDS             complement(9903..10688)
                     /locus_tag="VXE01_001444"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV0750335.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            11013..12377
                     /locus_tag="VXE01_001445"
     CDS             11013..12377
                     /locus_tag="VXE01_001445"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV0750336.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            12380..12751
                     /locus_tag="VXE01_001446"
     CDS             12380..12751
                     /locus_tag="VXE01_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV0750337.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            12965..14239
                     /gene="serS"
                     /locus_tag="VXE01_001447"
     CDS             12965..14239
                     /gene="serS"
                     /locus_tag="VXE01_001447"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV0750338.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILIK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDASVTIPEALRPYMGGAEVIKP"
     gene            complement(14264..15163)
                     /locus_tag="VXE01_001448"
     CDS             complement(14264..15163)
                     /locus_tag="VXE01_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV0750339.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(15273..15821)
                     /locus_tag="VXE01_001449"
     CDS             complement(15273..15821)
                     /locus_tag="VXE01_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV0750340.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(16039..17361)
                     /locus_tag="VXE01_001450"
     CDS             complement(16039..17361)
                     /locus_tag="VXE01_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV0750341.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(17452..17540)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(17704..20040)
                     /locus_tag="VXE01_001451"
     CDS             complement(17704..20040)
                     /locus_tag="VXE01_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV0750342.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKEIELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(20144..20692)
                     /locus_tag="VXE01_001452"
     CDS             complement(20144..20692)
                     /locus_tag="VXE01_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV0750343.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(20689..20991)
                     /gene="zapA"
                     /locus_tag="VXE01_001453"
     CDS             complement(20689..20991)
                     /gene="zapA"
                     /locus_tag="VXE01_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV0750344.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            21078..21998
                     /locus_tag="VXE01_001454"
     CDS             21078..21998
                     /locus_tag="VXE01_001454"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV0750345.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISNPISNPI
                     SNPISNPISLEEKAEGKYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKV
                     ASQILQAYGMQGLNFCAKLHFKNTEKAKNA"
     gene            22010..22624
                     /gene="lepB"
                     /locus_tag="VXE01_001455"
     CDS             22010..22624
                     /gene="lepB"
                     /locus_tag="VXE01_001455"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV0750346.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            22752..25118
                     /locus_tag="VXE01_001456"
     CDS             22752..25118
                     /locus_tag="VXE01_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV0750347.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEKELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSSISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(25166..26449)
                     /locus_tag="VXE01_001457"
     CDS             complement(25166..26449)
                     /locus_tag="VXE01_001457"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV0750348.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT         7668 a         6183 c         5179 g         7616 t
ORIGIN      
        1 atttttgtaa gcttacatct acagtataca tcttttttgt ctattttata gtctatctcc
       61 tcaactgtca atttttcaac ctgaattgca tttttccata aaaaatgaga cctttctagt
      121 ctcatttagt cattcttagt attttctaaa tcgttgatag cgttcttcca gcaactcttc
      181 tagcggtttt tgtgaaagtc tagccagctc cgtttggagt tcttttttga cactcttaat
      241 cagttcttta ctagaaagtc ctacttcaga aatcacctta tccaccacgt ccatttctag
      301 cagctcatgc gaagtgattt tcatcaattc tgccgcttcc atggcacgac tgccatcctt
      361 ccatagaatg gaagcaaagc cttctggact tagaatggca taaatagaat tttccagcat
      421 ccagacacgg tccgcgactg ctagagccag agccccacct gaaccacctt caccgataat
      481 gatagcaata atcggaactt tcaggtcact catttccatg agattgcgag cgatagcttc
      541 cccttgacca cgttcttccg ctccgacacc aggataagca cctgctgtat tgataaaggt
      601 cacaactgga cggccaaatt tctcagcatg tttcatcaac cgcagtgcct ttcggtagcc
      661 ttctggatgt ggttggccaa aattccgttt gaggttgtct tgcaaactct tgcctttttg
      721 gataccaacc actgttacag cttgatctcc aagccaacca ataccaccaa caactgcacc
      781 atcatcacga aaagaacggt caccatgtaa ttggataaat tcatcaaaaa tgcctgtcgc
      841 aaagtccaag gttgtcaagc gactctgctc acgcgcttct ctgactattt ttgcaatatt
      901 catctaggac tccctccatg caatctgact aggctagcaa tcgtatctgg taagtctctt
      961 cttttgacaa tagcatccac aaagccatgt tctaatagga attctgcctt ttggaaatcc
     1021 tcaggcaagc tttcacgaac cgtattttca atcacacgac gcccagcaaa accaaccaag
     1081 ctctgtggtt cagccagaat gatatcgcct tccatagcga aagaagctgt cacaccacca
     1141 gtcgttggat ctgtcaaaat ggtcaggtaa aagagaccag catttgaatg acgtttaacc
     1201 gccgcagaga tcttagccat ctgcatgaga ctcatgattc cttcctgcat acgggctcca
     1261 ccagaggctg tgaataggac aactggcaat ttttcgacag tcgcatactc aaacaaacga
     1321 gtgatttttt cacctacaac cgtacccata gaagccatga taaagttaga atccataatc
     1381 ccgagagcca cagtctgacc tttaataaga gcagttcctg tcacaacggc ttcatgcaga
     1441 cctgtttttt cacgcataga tgccagtttc ttttggtaac cagggaaatg caagggatcc
     1501 ttgctttcaa tccctgtaaa caattctttg aaggttccca tatcaatcgt caaagccaag
     1561 cgttcttggg cagaaatacg aaaggtatag ctacagtgcg gacagatacg ttcacttccc
     1621 agatccttct gatagatggt atgcttacag cctggacact gggaaaataa ttcatctgga
     1681 acctctggct tagcttgagg tttttcccta accgaacgat tgggattgat tcgaatatac
     1741 ttatcttttt tactaaatag agccattgat tccccttttc ggtttaaact cttaaagtca
     1801 ttttattctt tttcttgata tttaggtaag aaggtttcca tcaagaagga agtatcataa
     1861 tccccagcaa tgacattgcg atctgaaatg aggtcaagct ggaaatctgc attggtctgc
     1921 actccttcaa tctctaattc atagagggca cgttgcattt tcatcaaggc gtcaaaacga
     1981 ttttcgccgt gtactatgat tttggcaatc atactatcat aataaggcgg aatggtataa
     2041 cctggataaa ctgctgaatc cacgcgcaag ccaactccac cacttggcag atagagatta
     2101 gtaatcttac ctggacttgg agcaaagtta aaggctgggt tttctgcatt gatacgacac
     2161 tcgatggcat gaccgcgtag gacaatatct tcttgcttaa cagacaaagg ctgacctgcc
     2221 gcaatgcaaa tctgttcctt aacgatatca acacctgaaa caaactctgt tactggatgt
     2281 tctacctgaa cacgagtatt catctccatg aaatagaaat tgctacttgc ttcatcaaga
     2341 agaaattcaa tggttcctgc attctcatag ccaacaaact ctgccgctcg aacagcagca
     2401 gcacctattt catgacgcag cgtttttccg attgcaatcg agggactttc ttccaaaacc
     2461 ttttggttat tcctttgaag agaacaatcc cgctcaccca agtgaatcac atgtccatgc
     2521 tcatcaccta ggatttgaac ctcaatgtgc cgagctggat agataacccg ttctatgtac
     2581 atggcaccat tgccataatt ggccttggcc tcactagagg cagtttcaaa ggcagaaacg
     2641 aggtcatctg gtttttcaac cttacgaatc cctttaccac ctccacctgc tgaagccttg
     2701 agcataacag gatagccaat tttttcagca acaatcaaag cttcttcaga gttatgcact
     2761 tctccatctg aacctggtat aacaggcaca cctgctttaa tcatctgagc acgcgcattg
     2821 atcttatccc ccatcatatc cataacatga ccagatggac cgataaactt gatacctact
     2881 tcttcacaca tggtcgcaaa tttggaattt tcactgagaa atccaaaacc agggtgaata
     2941 gcttctgcct cagtcaagac tgcagctgat agaactgcat taatattgag ataagactct
     3001 gttgccttgc caggaccaat acaaactgct tcatctgcca aaagcgtatg aagagcttcc
     3061 ttatcagcag ttgaataaac cgctaccgtc gcaatcccca attcacgtgc cgcacggata
     3121 atacgaaccg caatttcacc acgattggca attaaaattt ttcgaaacat ggagaacctc
     3181 cttagttccc aattgcaaaa gtaaggatac cactggctgc aagcttgcca tccacttcag
     3241 cctttgcttc aaccacagct atggtgccac gacattttac aaaagtcgct gtcataacca
     3301 attggtcgcc tggtacaact tgcttcttga acttaacctt gtccatacca gcgtaaaaga
     3361 ccagttttcc tttattttca ggttttgata actccaacac accagcagtt tgcgccaagg
     3421 cttccataat cagaacacct ggcataactg ggtattgagg aaagtggccg ttaaagaaag
     3481 gttcgttaat ggtcacattt ttgatagcaa caatggtatc ctcgctcact tccaagacac
     3541 ggtccactag aagcatagga taacggtggg gaagagcttc tttgatttct tgaatatcga
     3601 tcatttgata cgtaccaatc ctttaccaaa ctcaaccatt tcttcgttag agacgagaat
     3661 ttccgttacc acaccatcct taggagctgg gatttcattc atgactttca tggcttcgat
     3721 aattaccaat gtttgacctt ttttgacact atcaccaact gtaacgaagg caggtttatc
     3781 tggtccagca gccaagtaaa ccactccaac aagtggactc tctacaagat ttccctcagt
     3841 agccacactt gcttcagctg gagctggaac ttcttctgct acagtctctg ctggagcaga
     3901 tgtaggagct actggactcg gtgttgctag aacgggtgct ggagcgactt gagttgcaac
     3961 ttcaggcaca ggtctcgctt cattcttgct aaactgcaac tcatccgtcc catttttata
     4021 agaaaattct ctcaaacttg actggtcaaa ttgagtcatc aagtctttaa tatcgtttaa
     4081 attcatactt atctattctc ccaacgtttg aaagcaagaa ctgcattgtg gcctccaaaa
     4141 ccaaaagtat ttgaaatagc gtatggaatt tctttctcca agccttgtcc ataaacgaca
     4201 ttagcttcga tataatctga tacttcactt gtcccagctg tcattggtac aaagttatgg
     4261 cgcatagctt cgatggtgac gatagcttct actgcacccg cagcccccag caaatgtcct
     4321 gtaaaagact tggttgatga tacaggtact tccttaccaa gaacagctac gatagctcca
     4381 ctttctcctt tttcattggc aggagttgac gttccgtgag cattgacata ggctacttgc
     4441 tctggagaaa tctcagcttc ttccaaggct agtttgatgg ccttgatagc tccctgacct
     4501 tctggatgtg gagaagtcat gtggtaggca tcacaagtat ttccgtaacc aaccacttca
     4561 gccaggatag tagctccacg tttttcagcg tgttcaagac tttctaaaac caacatccct
     4621 gaaccttcac ccataacaaa cccattgcga tccttatcaa atgggatcga agcacgagtt
     4681 ggatcctctg tagtagagag agctgttaag gcttggaaac cagcgatggc aaaaggtgtg
     4741 atagaagctt ctgttcctcc caccaacatc acatcttgga aaccaaactt aatggagcgg
     4801 aaggcatccc caatcgcatc atttgatgaa gagcaggcag tattgataga tttacaaaca
     4861 ccgtttgcac caaaacgcat ggctacattc ccagaagcca tatttggtaa agcttttgga
     4921 agagtcattg gtttgacacg tttgggtcct ttttcatgaa ggcgaagtac ctgatcttca
     4981 atttccttga ttccaccaat accagatgca acgataacac caaaacgatc cctattaaga
     5041 gcctctacat caagattggc atgatttaca gcctcttggg ctgcatacaa ggcatataaa
     5101 gaatagttat caaaacggtt ggtatctttt tttacaaagt atttatcgaa cggaaaatct
     5161 tggatttctg ccgcattatg cacatcaaag tcactatgat caaattttgt aatgccacca
     5221 atgccgattt tcccagttgc taaactattc caaaattctt ctggtgtatt tccgattgga
     5281 gatgttactc cataacctgt taccactact cgatttagtt tcattctttt cacctctagc
     5341 tttcgctaca tacttaagcc accatcaatg gcaatcactt gaccagttag ataatcttgg
     5401 cctgctaaaa atactgtcaa atctgcaacc tgctctgcct gcccaaattc tttcatcgga
     5461 atctgagcta gtgtagcttc cttaatctta tctgataaga tagctgtcat atcagactca
     5521 atcattcctg gagcaatcac attgactcgt atattccgac tagcgacctc gcgtgccaca
     5581 gacttggtaa agccaatcaa gccagcctta gaagcagcat agttagcttg accaatattc
     5641 cccatcaaac caacaacact agacatatta atgatagcac cttctctggc tttcatcatc
     5701 ggtttcaaga ctgattgtgt catattaaag gcaccagtca gattgacctt gagcactttt
     5761 tcaaaatctg cttctgtcat cttgagcata agagtatctt gggtaatccc tgcattgttg
     5821 accaaaacat ctactgaacc cagttctgca atagcttgat caatcatacg cttagcgtct
     5881 gcaaaatctg atacatctcc tgaaatggga accaccttga taccatagtt tgaaaactca
     5941 gcgagcaatt cttctgagat tgccccacga ctgtttaaga caatgttggc tcctgcttga
     6001 gcaaacttgt gggcgatggc aagaccaatt ccacgactcg aacctgtaat aaagatattt
     6061 ttatgttcta gtttcatttt tttcctttca aaacttctac ttattttagt ctatttttct
     6121 aaaagtgcta ctaaactcgc ttgatcttcc acatgagcta agtgagcagt ttgatcaatt
     6181 tttttaacaa aacctgacaa gactttcccc ggtccaatct cgataaagtt gcttatgcct
     6241 gcttcttgca tgaccccaat actttcatag aaacgaacgg gttccttgac ctgacgcgtc
     6301 aagagctgag caatgtcctc tttttgcatc acagcagctt ctgtattgcc gactagggga
     6361 caagtaaaat ctgaaaaact tacctgagct agagtttcag ctagtttctg gctagctggc
     6421 tcaaggagag cggtgtgaaa gggacctgac accttaagag gaatcaagcg tttggcacct
     6481 gcttcttgca aaagttcaac cgctcgatca actgcaacca cttctccagc aatgacgatt
     6541 tgtgcaggtg tgttatagtt ggctggagta accactccaa gttcagaagc tttttgacag
     6601 gcttcttcaa tgacctctac tggcgtattg agaactgcta ccatcttgcc agagtcagca
     6661 ggagccgctt cttccatata ggctccacgc ttagctacca aggcaaccgc atcttcaaaa
     6721 tccaaggcgc cgcttgccac caaggcagag tattctccaa gagacaaacc agcaaccata
     6781 tcaggctgat agcccttttc ttgcaataaa cggtagatag caaccgaagt cgctagaatg
     6841 gctggttgcg tatagcgggt ctgattgagt ttgtcttctt ccgtatcgat gagataacgc
     6901 aaatcataac ctagcacctg actcgctcga tcaatcgttt ctttaacaat cggatactga
     6961 tcatagaaat cccgtcccat ccctagatac tgggcacctt gaccagcaaa taaaaaggct
     7021 gttttagtca tttcttacaa ctcctgtcca gcgagaggct tcttcttgaa ttttcttagc
     7081 ggctccgtaa tacaaatctt ttaggatttc ttcagctgtt tcttctttag aaacaagccc
     7141 tgcgatttga cctgccatga cagagccacc ctccacatca ccgtgaacaa ctgctttggc
     7201 tagggcaccg gctcccattt gttcaaagat ttctaaatca ggatcttcct gcttaaaggc
     7261 atctttttca gccagttcaa aatctctagt caactgattt ttaatagcac gaacagcatg
     7321 accaaagtgc tgagctgaaa tcgtagtgtc aatatccctt gcttttaaaa ttttctcctt
     7381 gtagtttgga tgggcattcg actcttttgc aactacaaac cgtgtcccca cctgtacagc
     7441 ctctgcacct agcataaagc cagccgcagc accttcacca tccgcaattc ctcctgcagc
     7501 aataacagga atagatacag ctgtggctac ctgtcgcacc aaggtcatgg ttgttaattt
     7561 accgatatgc cccccagctt ccattccttc tgcaataaca gcgtctgcac cgattttttc
     7621 catgcgttta gctaaagcga cactaggaac gacaggaata acgattatcc cagcttcatg
     7681 gaaacgttcc atatacttgc ttggatttcc tgctcctgtt gtgacaactt taacaccttc
     7741 ttcaataacg agatccacga tatcttccac aaagggagat aagagcatga tgttgacccc
     7801 aaagggttta tcagtcaatg atttgatttt atcaatattg gccttgacaa cttctttcgg
     7861 ggcatttccc ccaccgataa ttcctaatcc tccagccttg gaaacagccc ctgccaaatc
     7921 accatcagca acccaggcca tccctccttg gaaaatagga tagtcaatct tcaataattc
     7981 tgtaatacgc gttttcatag tgcctccaac cttccttgct tacgtaatag ttcgatttca
     8041 ccataatttg acagtcaaac tattacctaa acaagaggga gtgggtttct ccctactcct
     8101 tctactaata ttctgcttat tttgcttgct cttcaacgta agcaaccaag tcaccaactg
     8161 ttttcaagtc attttctgct tcgatttgga tatcaaaagc atcttcgatt tctgagatta
     8221 cttggaacaa gtccaatgaa tctgcgtcca aatcatcaaa agttgattca agtgttactt
     8281 ctgatgcgtc ttttccaagt tcttcaacga taatttcttg tactttttca aatactgcca
     8341 tgataggact cctttaaaat aaatagtttt tttataacaa tgtgttcacc acatgattac
     8401 ctaaattgta agaatgagcg tgccccaggt caagcctcca ccgaagcctg atagaagaac
     8461 agtctggcta ccatctaaag ggatgagacc ttgttctaca cactctgaaa gtaaaatcgg
     8521 gatactggct gcactggtat tgccatattc catcatattg gctggaagtt tggctcggtc
     8581 aacaccaatt tttctagcca tcttatccaa aatacggtca ttggcttgat gaagtagcag
     8641 ataatccaag tctgtcacct ctataggaga ttcatcaata gtctgcttga tagacttggc
     8701 tacatctcga atggcaaaat caaagactgt gcgtccatcc atcttcaaaa atgaatctgc
     8761 actttcttga tctgaaaatg gagaatgcaa acctgaatgc ccataagtta aacactcgct
     8821 gcgacttcca tcgctattga gactctcagc taagaaatgc tcttgctcgc tagcttctaa
     8881 caagacacca ccagcaccat ctccaaacaa cacagctgtt gatcgatccg accaatcgac
     8941 tgccttagag agggtttcac taccaatcac caagcctttt tgaaagcgac cagaagcgat
     9001 aaacttttca gcagttgaaa gagcaaatac aaatccactg caagccgcgg ttaagtcaaa
     9061 agcaaaggct ttattagcac caatattagc ttgaacacga gcagctgtag agggcatcat
     9121 cgaatctgga gtaatggtag ctaggatgat aaaatccagt tcttctcctg ttattccagc
     9181 ttttgccatc agtttcttag caacctctgt agccaaatca ctggtagatt ctgttcttga
     9241 aatatgcctt tgtcgtattc ccgttcgact tgaaatccac tcatcattgg tatccataat
     9301 ctgagccaag tcgtgatttg taaccacttg ctctggcaca taatgagcaa cctgacttat
     9361 ttttgcaaaa gccattattt caaatcctcc aaaaattggt aaagattagt caagccttta
     9421 cccatgacag caatttcttc ctcgctcatg ccatcaataa ttttttctac catggccttg
     9481 tggaagcgtt tatgcagtct atgaatcaag cgacccttct ttgtcaaatg cagatgcacc
     9541 acacgacgat cctgttctga ccgaactcgc tcaatgtagc ccttacgctc taaattgttc
     9601 aaacttgtcg taacagttcc aagagttacc atcaactctt ttgacacttg acttggagtc
     9661 acatctggag ccttaccgat gacatcaatc gtatgcattt ctttgatgga gatatcctta
     9721 aaacgactac ctctcaagtt cacttcctca attacaagga cattgttaaa tatagatgtt
     9781 aaatattcat tgattcgttg gtagtccatt tttcatatcc ctccttctta aaaaaacttt
     9841 tacaatcaaa acatttgaca gaaagaatta tatcaaaatt caaagaatga tgcaagtatt
     9901 ttttattttc ctgtaaattt aggtcttctt ctctccgaat gagctcgcac tccttctttg
     9961 aaatcctctg tttgagctaa ggatttctgt aggttcagtt ctaaagtagc gtaaccctgc
    10021 cagtctttaa attggctctc ccaaaccaac ttcttaatgg cagcatagga attacttgaa
    10081 gcacgtctta attttttaag aagctgttct ctcgtctttt caagtttttc agcttcagaa
    10141 acgcggtaaa ccaaccccca ttctagggct ttttctgccg ttaaagcctc tcctgtcata
    10201 gctaattgag cagcacgcgt cacaccgata ctgcggctca agagatgaat tccccctgca
    10261 tctggagcca aaccaacacc aacaaaggct tggataaact tagccttatc cgtcgccaaa
    10321 cagaaatctg ccgcaacagc catattcgct gcggcacctg caacagcacc gtcaacttcc
    10381 attaaaacag gtttggctat ttgcttgatt ttataagaaa tcgtattgac caactctgcg
    10441 atttttgtca atgatggaat atcatcctca tccactgctc gcttcatctc taccaaatct
    10501 cccccaactg agaagacctt tccattggca ttgattaaga taaaatgcac agctggattt
    10561 tcttctgcca aagtcagagc ttctaaaatc tcctcacaca tgggaatatg aaaaccattt
    10621 gcgacctcag gacggttcaa ggtaaggatt gccaagtcct cttcaagttg ataaataatg
    10681 tgttccatca gggctccttt ttattttata agcagtttat actcttcgaa aatctcttca
    10741 aaccgcgtca gcttccatct gcaacctcaa aacagtattt tgagctgact tcgtctagct
    10801 tcctagtttg ctctttgatt ttcattgagt gttaaattat ttcactgtca aagtatatct
    10861 tttttaggat cagaaagcaa gaaaaaatcg actgaaagtg tctcagccga taagaaaagc
    10921 tcgctttagg ctagaaagca tcttattctc ttcattgaaa aaagcctttc tttctgctat
    10981 aatcgtataa aatacttact ttaggagttc ttatgaaagt tgttaaattt ggaggtagtt
    11041 ctcttgcctc tgctagtcaa ttagaaaaag ttttaaacat cgtcaaaagc gattcagagc
    11101 gtcgttttgt agtcgtttct gcgcctggta aacgcaatgc tgaagatact aaggttacgg
    11161 atgccctgat taaatactac cgcgactatg ttgcgggtaa cgatattagc aagagccaaa
    11221 gctggattat cgaccgctat gctgctatgg ttagtgaatt gggactaaaa ccagctgtgc
    11281 tagaaaaaat ttctaaaagc attcacgcct tggccactct tcctattgaa gaaaatgaat
    11341 ttctctacga tactttccta gcagccggtg aaaataacaa tgccaaattg attgctgcct
    11401 actttaacca aaatggtatc gatgcacgct atatgcaccc tagagaagct gggattgtgg
    11461 tcacaagtga acctggtcac gctcgcatca ttccatcaag ttatgacaag attgaagaat
    11521 tgacaaacac caatgaagtc cttgtcattc ctggtttctt tggtgtcact aaggaaaatc
    11581 aaatctgtac tttctcacgt ggaggttctg atattacagg ttctatcatt gctgctggtg
    11641 tcaaagctga cctctatgaa aactttacgg acgttgatgg tatctttgca gcccaccctg
    11701 gtattatcca ccaaccacac tcgattcctg agttgaccta ccgtgaaatg cgcgagttgg
    11761 cctatgcagg cttctcagtc cttcatgacg aggctcttct tcctgcctac cgtggaaaaa
    11821 ttcctctggt tatcaagaat accaacaacc ctgaccatcc aggtactcgt atcgttctaa
    11881 aacacagtaa tgatgaattt ccagttgtgg gaattgctgg tgactcaggc tttgtcagca
    11941 ttaacatgtc gaaatacctc atgaaccgtg aggttggatt tggccgcaag gttctgcaaa
    12001 tcctggaaga acttaacatc ggttgggaac atatgccaac aggtatcgac gatctttcta
    12061 tcattctccg ttctcgccaa ctaactccca tcaaggaaga agaaatcctg cgtcagttgg
    12121 ttcaaaaggc taaagtagat catgcagaaa tcgaacacga cctttctatc attatgattg
    12181 ttggtgaaaa aatgaagagc catatcggag tgactgctac tgcgacacgc gctctatctg
    12241 aaaacaaaat caacatccag atgatgtctc aaggttctag tgaagtttct attatgtttg
    12301 ttgtcaataa agaccaagag aaagcagcaa ttaaagccct ctacaatgcc ttttttggag
    12361 aaagtaagga agactaagca tggctcaatc acttaacaaa acagtactcc tcagtacgac
    12421 aggcacttcc tacctctcta tcgctgggaa agttgggaaa ttccttgtcg gagatcaggc
    12481 tttggaattt tacccagatg tcaatgtcga acaatttatc cagattcctt ggagccatat
    12541 caatcagatt ggagccaatg tcactggacg caaaatcagc cgccacttcg aagtctttac
    12601 agacaaagga aaattcctct ttgcttcaaa agactcaggt gccattctca aaattgcacg
    12661 cgaaaaacta ggcaatgaca aggtcgtcaa acttccgacc ctgattcaga caattagcca
    12721 aaaatttaaa aatctatttg caaaaaagta gaaactttag tataatcata gcaacggata
    12781 agtaggttat cttcttcttt cagaaagtct gcgggtactg cgagcagata ggagggatag
    12841 gtgaaattct accgttagta acaattacat acacaatcaa gtgcacacct gtgaagttgg
    12901 atggaaccgt ggccctgcca ctccaacgtt ttgtcaggcg tgcttttttc ataaaggagt
    12961 tcttatgtta gatatcaaac gtattcgtac agattttgaa gctgtcgcag aaaaattagc
    13021 tacacgtggt gtagatgctg ctgtcttgaa tgaaatgaaa gaaatcgatg ctaaacgtcg
    13081 taacatcttg attaaggttg aaactctcaa agcagaacgt aacacagttt ctgctgagat
    13141 tgcccaagct aagcgcaaca aggaaaatac agatgacaag attgctgcca tgcaaaatct
    13201 atctgctgag gttaaagcct tggatgctga attggcagaa atcgatgcta aattgacaga
    13261 atttacaacg actcttccaa atatcccagc tgacagcgtt cctgttgggg ctgacgaaga
    13321 cgacaatgtg gaagttcgcc gttggggtac tccacgcgag tttgacttcg aacctaaagc
    13381 tcactgggat ctcggtgaag accttggtat ccttgactgg gaacgcggtg gtaaggtaac
    13441 aggcgctcgc ttcctcttct ataaaggcct cggtgctcgt ttggaacgtg ctatctacaa
    13501 ctttatgttg gatgaacatg gaaaagaagg ctatactgaa gtcatcacac cttacatagt
    13561 caaccatgat tctatgtttg gtactggtca gtatccaaaa tttaaggaag atacttttga
    13621 actcagcgat accaactttg tcttgattcc aactgctgaa gttcctctga caaactacta
    13681 ccgtgatgaa atcttagacg gcaaagatct tccaatctac ttcactgcca tgagtccgtc
    13741 attccgttct gaggctggtt ctgccggtcg tgatacgcgt ggcttgatcc gtttgcacca
    13801 attccacaag gttgaaatgg tcaaatttgc caaaccagaa gaatcttacg aagaattgga
    13861 aaaaatgaca gccaacgctg aaaacattct tcaaaaactc aaccttccat accgtgtcgt
    13921 tgctctctct actggagata tgggcttctc agctgcgaag acttacgact tggaagtgtg
    13981 gattccagca caaaacaatt accgtgaaat ctcaagctgt tcaaacacag aagatttcca
    14041 agcccgtcgt gcccaaatcc gttaccgtga tgaagcagat ggcaaggtga aactccttca
    14101 taccttgaac ggttctggac ttgcagttgg acgtacagtg gctgcaattc ttgaaaatta
    14161 ccaaaatgaa gatgcttctg tgaccatccc agaagcactt cgtccataca tgggtggagc
    14221 tgaagtcatc aaaccataaa aaataaggtt tagctatttc tagctagacc ttttttcgta
    14281 accaaatcag ataagcacct agtacaaaga ataaaatagt taggcatata atggtttcag
    14341 ccaataccag gtaatccaga aatggaagtt tcaaaattcc ctgagccatc ttgagcgagg
    14401 tcgctgtgat aatggttggg aaggtgaggg ctgagaaggc tggttgaaaa ccttgtttta
    14461 aaatgttggg cagacgagtt aaaacaaaga aaaagaagga ttgagaagcc aaaatcatga
    14521 caatcaagac ccaagtcggc aggctggttc ctcctactcg aactagagaa gccaagagta
    14581 gagagaaagg agcacagtag attccttctt gtccaagcaa ggctagtggg agtggatgtt
    14641 tctttaaatc gctataaata aggggataga gatagaaggt caagagaaaa ccaaaactca
    14701 aggtcgcata ggcaatttcg ataataccta ccagaggata ggtcaaggca gccactgcta
    14761 tccccacata gagaaccgtc caacttggag tggcatgaac cctccgccct ggacaagcaa
    14821 acttgatggt aaaaccagca atcaaggtca aatccaagag aaatgaaaac caccaaatcc
    14881 cttgtgctac caaaggaaga taagagaata cgcgaaagac ataggtcgat aaaatcatcc
    14941 cagccatagg aaaggttgcc attcctgaca aaagaggggg cttggtcaat tcttgcttgg
    15001 tttctttcca attaaagaga tgcagaatta gaaagtaaat ccataaaacc aaaccagtca
    15061 gactaaaaag atgggataga accggcaacg tatctaaaat aagatttcca gctcctgcca
    15121 aacctagcaa acaacctgaa aatactaagg ggagtttttt catcctaacc tccaataatc
    15181 atgttagttt cagtataaca taaaagcgct taaatgagga tttaaaaaaa cgaagtccgc
    15241 ttatttcaga cttcatttta ctcagatatg aattaggcat aaggttgcaa ttctggatta
    15301 attggtgtat tagctaagtt gttggcatag ttacagagga ttgctaggct gacaccaaaa
    15361 accacatcca aggcattttg ttgagtgtag ccagcttcta aaaactcaga caaggcttca
    15421 tctcctacac gacccttggt attgataact gccaaggtaa acttagctag ggtatccaat
    15481 ttaggatctg tttcaattgg agtacgattg cgaagagctt gaatcaagtc atcattcatc
    15541 tggatttgtt tgatggaaaa ggctgtgtga cctgcgacac agaaggcaca accattggtc
    15601 acggctgccg tgatttgcac cacttcacgc tcaacgggtg tcaggctgtt gcgacggtgg
    15661 atagatgaga caatttgata ggcttctaaa acagtcgggg cattggccaa gagaccgatt
    15721 aggttgggaa tatagccatt gttgtctttt tctactgttt caagaatttc tttcacttct
    15781 gctggtgctg actctactgt atggatagta aatgttgtca taagatacct cttttcttat
    15841 tattgacact aatattattg gaaaatctta taaaatcctg attcctaagt ttatctaaga
    15901 taaagcttta ttctctcata agattttcgt tgttatatta gtttatcaca cttccaatca
    15961 cttgcataat atatattata tatcaggctg ataaaaatta tttataggca aaaaaatcac
    16021 acgagctgtg tgattccatt atttgtcaaa atacttttta gtttcagcaa taacgactgg
    16081 cgacaagacc aagagggcaa tcaagtttgg cagagccatc aaggcgttaa cgatatctgc
    16141 gataatccag accatatcca actcgataaa tcctcctaac aagaccatga gcacaaaaac
    16201 cacacggtag agccagataa agcgaacccc aaagaggaac tcaaaacagc gttctccgta
    16261 atagttccaa cctagaatcg ttgtaaaggc aaaaagtaca aggaagatgg tcaagagggc
    16321 aggcccaaag tgtgaaaaga ctgttgagaa agctgactga gtcaaggcaa ccccattcaa
    16381 gtcaccactc caaactccag ttaccaagat ggtcaaacca gttagagtac aaatgatgag
    16441 ggtatcaata aaggttcctg tcatggaaat caaaccttgc tctactggtt catttgtctt
    16501 ggcagctgca gctgcaatag gagcagaacc cagaccagat tcgtttgaga acacaccacg
    16561 cgccacacca ttttgaatag ccatccgaac gctagcacca gcaaatccac ctaccgcagc
    16621 aaggggacta aaagctgagg taaagactaa agcgattgtg ccagggattt ttccgatatt
    16681 aaagaaaata actgtaagag ttcctaagat ataaatgatg gccataaaag gaacaacagt
    16741 agttgaaacc ttagaaatag acttgagtcc accaaagact gcaatcgcta caaagacaga
    16801 caagacgaga gctgtgatgg ctggcgaaat cgtcgttgta ttttggatag attctgcaat
    16861 cgagttgact tgggtgaagg ttccgattcc caagagagca accaatactc ctgctactgc
    16921 aaacaaaaca gcaagtggtc gccacttttc tcccatccct agaaggatat aatgcatggg
    16981 acctcccgct actgcaccat ggtcgtcctt ggtgcggtat ttgatggcca agagtccttc
    17041 cgcatacttg gtagccattc caaagaaagc cgccatccac atccaaaata gagctcctgg
    17101 tccaccaacc ttgatagccg tcgcaactcc tatgatattt cctgttccaa cagttgatgc
    17161 caaggctgta cacagagctg caaaactgga tacatcacca tgtcccttat cctggataaa
    17221 aataagctga aaagccttgg gcagacgcaa aacctgcaag agtcctagcc gaatagttag
    17281 gtaaatccct gttccgacca ataaaatcaa gaggggcggt ccccaagcaa aagcatcgat
    17341 tgatttaagc aattctaaca tttccttctc ctatcgtttc aaccccaaaa gaaagagcac
    17401 atgcaagata catgtactct ggaatgctta gataaatgct aaaaagcggt ctatcctagc
    17461 tctgtccttt tacctgagag tttgagcagt tgcctgcctt gccccttcgg tgcctttacg
    17521 gtctctccag agttccgtcc atttacagtc atggaaaatc aaacgattcc ccacttctat
    17581 taaacttcat tcggtgttgg tatttaattg attctaattt tacaaaaaat gttggctttt
    17641 gtcaatgtgt ttattagtaa aaattagttc aacagttttt actttataaa gtccagaata
    17701 ctgctatcct ttaaaagtga caatagtcgc accactgcct ccagcatttt gtggggcata
    17761 gccgaaactc ttgacatgtt tgtttctttg caagtatttg gtaactcctt cacggatgac
    17821 tcctgttccg ataccatgga tgatatcaac ttgagccata ttgttaagca aggcttggtc
    17881 gatgaaggta tctagctcat tcatggcttc ttcatagcgc ttgcctcgaa gatccagtct
    17941 agcttgaggt cctcgcccag aagttcgttt cacaacattg acctgtttct tcttgactgg
    18001 tttttcttgc tgggcttgaa caagatcaaa ctctttctct tccaaggtca tcttaatcaa
    18061 gccaacttgg gcttcccagc ggccgtcctt gagttgactg gtcaaggtac cacgctgacc
    18121 ataactgaga accacgatat catctcccac ctttggagct cgttttttct tggccttttg
    18181 aaggaccttg tttttagaca agtccacttt ttcaggagcc aattttttca acttggcctt
    18241 ggcttcaatg atttcgtggg gcttgagttg ggatttactg tggagatttt tgagaatctg
    18301 gtcactttca cttagggcca tatccacaat ctcagcagcc tgttcacgcg ccttgttaag
    18361 ctcgatttcc ttttcacgat taagctcgtt gtagagtttt tttagcgcac ggttcatctt
    18421 gagattttct tgctccacct cacggatatt gtccaagcgt ttgcggcttt ccagcgtctg
    18481 ctcttctaat tgctcaatga tacgattgac gtcattgtcc tgatcgatct gctgactggc
    18541 atctcctacg ataacttcag ataggcctag acgtttggca atttcaaagg cattacttcg
    18601 gccaggaaca ccctgcataa agcgataggt cgggcgaaga gttgcagtat caaactccat
    18661 actggcattt tgcacaaagg ctgtctcaat accgtaggcc ttgagttctg gatagtgggt
    18721 cgtcgccatg gtcttgattt gacgcaggcg aaggtcctcc agaatagcca tggcaagggc
    18781 tgctccctct tggggatcag taccagcccc caactcatcc aaaagtaaga gtgaatgttg
    18841 gttgaccttg ccaagaatat ccacgatatt ggtcatatgg ctagagaagg tagacaagct
    18901 ctgctcaata gactgctcat ctccaatatc agcaaagatt tcttcaaaaa taccaacacg
    18961 acttcccttg tctgctaaaa tcggcaatcc tgactgggcc atgacctgtg tcaagcccag
    19021 agttttgagc atgatggtct tcccacctgt attgggacct gtaatgacaa tagctgttaa
    19081 atcttgacca aaatagacat catttgcgac ggcatttttg accaaaggat ggcagacatg
    19141 gagcagttga atctcttgat tttctgacag ctgaggcacg actgcttgtc tttcttggat
    19201 aaatcgaacc ttggcacgaa tcaagtccag atgaccgata atccaagcgt cattagcaat
    19261 ctcagccgca tgagggcgga cacgctcaga aatttcttgg agaatgcgaa gcatttcata
    19321 gcgctcatct gctcgcagac tagcaatttc ttcgctcagt ttgactacct cacgtggttc
    19381 gatatagacg gtgtttccac tagcagaaat atcatgaacg acacctgcaa tcttattgcg
    19441 gtaggtgttt ttgactggta aaacctgacg gccatttctg ctagcaacaa ttccttccgt
    19501 caacatctgc gctttttgct tgagcaagtc ttgtaaaaca tcgcgtacct gactctcgct
    19561 atcatgtatt tttcgacgga ttcgcgccaa ttcttcactg gcaaaatttt caatgaaacc
    19621 cgcatcatta aaggcctgaa gatttccttg taattgcgga aaatcatgta atttctcaaa
    19681 ccaaagggct aattcttcca agctgacatt ttccagattg gcgtaaaaac tttgaagttc
    19741 tcggctggta agaagcacgc gtttcaagag taggaactcc tcgatattga gatccgctcc
    19801 catctccaac ctcttgcaga ctcctgcaat ttccttagtt gagagaatag taaaatgcgg
    19861 ttgctcgacg aaaagagcct gcatttcttt catctcagca aaagcctgtt tgattttatc
    19921 tgctttggca gtcggagcca gctgtctcaa ttgctccaag ccctgctcgg tcaacaaatg
    19981 aggctcaaac aaggccttga ccttatcgaa ctctaatgtt tctaatattt tcttattcat
    20041 ctttatttcc ttgtctttga atgtctaggt gtggtagctt tttacattct gatagattcg
    20101 agtcaaatct gtaaacaaag ggctaggaaa actcctgccc tttttatccg attaaatttg
    20161 tcacccagat ttgtttgagc caactggttg ttatcggtat gctctggatg atgtgttttg
    20221 cgacgatact cttttcaaga ggattttgta taactgccat ggggatggtc gccaagattg
    20281 tcaaggccat ttgcaagaca aataaggtca ccaacatgga caagatacct gctgaaactt
    20341 ggaacaactt accacccagt tttttgctag gaatcaagtg taagagaaga ccaagcaaac
    20401 gaccaatgct atagacaatc ccaaatacaa gcaagtagcc gatacctgca taaaagacct
    20461 tatccagctg aaagagttga tccgatggga aaaagaaagt cccctgacct tcctgcgaat
    20521 ttgcataagg gagcaataaa tggaattgct ctccaagccc cttataaaac tggccagcca
    20581 taaaagccga tgccatggct gaaatcaggt aataaacctg taagagcagg cctctccgat
    20641 agccgatata aaatccccaa accaagacca atagaagaag gaatgaaatc ataaggaatc
    20701 ctcaatcttg ctctgttctt gcttacaagt cacaagcttg tgacggagtt cttctagctc
    20761 ttgctcctta tcgtcaaatt caatctcacg gctgagctga gttgataaac agttgactgc
    20821 caacaaaaga gcgattgttt catcatctgc gctaggcatt tgttctttaa ttgcttggta
    20881 tttttctgtc gcaaccttag cgatttcctc cataaaaagg ttgtcatgtt cgcttgtcaa
    20941 ggttaacgat tttttcccga atgtaaattt gaatcgattt agatttgcca taaaattcac
    21001 ctcacgatat tataccaaaa ttcgctaatt ttgtcagttt ttacaaattt tactgctttt
    21061 gtggtacaat agaaactatg gcaagtatca cactcacacc aagcgaaaag gatattcagg
    21121 cttttcttga acactatcaa accagtctgg ctcctagcaa gaatccctat atccgctact
    21181 ttttgaaact acctcaagca acggtttcta tctatacttc tggaaaaatc ttgcttcagg
    21241 gtgaaggggc tgaaaaatac gccagtttct ttggctatca agctgtagag caaaccagcg
    21301 gacaaaatct tcctttgatt gggacagatg aggtagggaa tggttcctac tttggtgggc
    21361 ttgcagttgt ggcttccttt gtcacacctg accagcatgc cttcttacga aaactcggtg
    21421 tgggagattc taagactctg accgaccaaa agattcgtca gattgctcct attctcaagg
    21481 aaaaaattca gcaccaggca ctccttctct cacccagcaa gtacaacgag gtcatcggag
    21541 accgctacaa tgctgtttcg gttaaggttg ccctccataa tcaggctatc tatctcctcc
    21601 ttcaaaaagg tgttcagcct gagaaaattg tgattgatgc ctttaccagt gctaaaaatt
    21661 atgacaagta cttggcacaa gagaccaatc gtttcagcaa tcctatcagc aatcctatca
    21721 gcaatcctat cagcaatcct atcagcaatc ctatcagctt agaagaaaag gctgagggca
    21781 aatacttggc tgtcgcagtt tcttctgtca ttgcgcgtga tctctttctg gaaaatcttg
    21841 aaaatttggg acgagaactg ggttatcagc ttccaagtgg agctggaacg gcttctgaca
    21901 aggtggctag ccagattttg caagcctatg gtatgcaggg actcaacttc tgcgccaaat
    21961 tgcactttaa aaatactgaa aaagcgaaaa acgcttagaa aggtaagtta tgaatttatt
    22021 taaaaatttc ttaaaagagt ggggattatt cctcctgatt ctgtcattac tagctttgag
    22081 ccgtatcttt ttttggagca atgttcgcgt agaaggacat tccatggatc cgaccctagc
    22141 ggatggtgaa atcctctttg ttgttaagca cctccctatt gaccgttttg atatcgtggt
    22201 ggcccatgag gaagatggca ataaggacat tgtcaaacgt gtcatcggaa tgcctggcga
    22261 taccatccgt tacgaaaatg ataaacttta catcaatgac aaagaaacgg acgagcctta
    22321 tctagcagac tatatcaaac gcttcaagga tgacaaactc caaagcactt actcaggcaa
    22381 gggctttgaa ggaaataaag gaactttctt tagaagtatc gctcaaaaag cccaagcctt
    22441 cacagttgat gtcaactaca acaccaactt tagctttact gttccagaag gagaatacct
    22501 tctcctcgga gatgaccgct tggtttcgag cgacagccgc cacgtaggta ccttcaaagc
    22561 aaaagatatc acaggggaag ctaaattccg cttctggcca atcacccgta tcggaacatt
    22621 ttaagagacc taagaggccg agaatcacca atctcagcct cttcttctat cgtgagaaaa
    22681 tgattggtaa ctatctaaac ttaccagaac agaaacacct caactctcac ctattcatgc
    22741 aaaggaattt tatggaagtt tatttttcag gaaccattga acggattatt tttgaaaatc
    22801 ccagcaattt ttatcgcatc ctcctcctag aaatcgacga tacggacgca gaggattttg
    22861 atgattttga aatcattgtc acaggaacca tggctgatgt aattgagggc gaagactata
    22921 ctttttgggg gcaaattgtc cagcactcca agtatggaga acaactgcaa atcagtcgtt
    22981 atgatcgcgc aaaaccaact agtaagggct tggtcaagta cttttcaagt agccatttca
    23041 aggggattgg tctcaagaca gctcagaaaa tcgtggatac ctatggcgaa aataccattg
    23101 acgaaatttt gcaacaccca gaaaagttag aaggcatcgc aggactctct gccaaaaatc
    23161 gcgaggcttt cgtctccact ctccgtctca actacggaac ggagatggtt ttggccaaac
    23221 tagccaacta cggcattccc aacaaactag cctttcagat tcaagacttt tacaaggaag
    23281 aaacccttga tgtggttgaa aattatccct accagctggt tgaggatatc aagggtttgg
    23341 gctttaccat tgctgaccaa ctagctgagg aactaggcat cgaaagtcag gctcctgaac
    23401 gcttccgcgc cggtctagtt cacagtcttt ttcaggcctg tatggaaaca ggggacacct
    23461 atgttgaagc acgggatttg ctggaacaaa cccttactct ccttgagtct tcccgtcccg
    23521 tggaactaga ccccagccaa gttgcccaag agctctccta cctgatcgaa gaagacaagg
    23581 ttcagcagat tgataccaag atctttgaca acagcctctt tttcgctgag gaaggcatcc
    23641 gcagtcactt ggttcgtatc cttgaaaaag gaaaacagaa gagtcatgat ttaaaaacca
    23701 ttcaaaaaca tatcactact atcgagaaag agcttggaat tgagtatgat aacattcaaa
    23761 aacaggctat ctgtgatgct atccagaata aggtctttat cctgacaggt ggacctggta
    23821 ctggtaagac aactgttatc aatgggatca tcgctgttta cgccctgtta gagggacttg
    23881 acctcaggaa gaaaagcaac ctgcccattc ttcttgctgc tccaactggt cgagctgctc
    23941 gtcgcatgaa tgaattgaca ggtttgccta gcgcgaccat acaccgccac ttgggaatga
    24001 caggtgacga tgataccagt catctggaag attacctaga tgctgacttt atcatcgtgg
    24061 atgaattctc tatggtggat acttggctgg ccaatcaact cttctccagt atctcttcta
    24121 acagtaagat cctcatcgta ggtgacagtg atcagctacc ttctgtcagt cctggacagg
    24181 ttctagcgga tctgcttcat attcctttga ttcctcagac tcgcttggaa aaaatttatc
    24241 gacaaagcga agaatcaacc atcgtcaccc tagctagtca gattcgacag ggcatcttgc
    24301 cagctgattt cacccaaaaa aaagctgacc gttcctactt tgaaattgct agtggccata
    24361 ttcctgccac cattgaaaaa atcttaggtg ccgccctcag aaatggtatt cctgcccgtg
    24421 atatccaagt tctggctcct atgtaccgag ggacggcagg gattgatgct atcaatcagc
    24481 tcatgcaaga cctgctcaat cccccacaaa aagatcaact cagttttgaa gctcctcagt
    24541 gccactatcg taagggagac aaggtcattc atttggttaa cgatgctgaa atcaatgtct
    24601 ttaatgggga tttaggagct atcacagacc tgattcctgg taaatacacc gaatcgaaac
    24661 aagacgagat tgtcattgat tttgatggta atgaagtctc ttacccccgt aacgaatggt
    24721 acaagattcg cttggcctat gccatgagta ttcataagtc tcagggaagt gagttcccag
    24781 ttgtcatcct gccgattact agtgctagcc gacgtatgct ggagcgaaat ctcatctaca
    24841 cagccattac acgtgccaaa agcaaactca tcttactagg cgaattacaa gccttcgact
    24901 atgctaccca acacatcgga actgcccgaa aaacctatct gattgaacgc ttcagtgatc
    24961 tactggagaa tgttgaagaa aagcaacaag ctgtctctga aacagtcaca tcaagtgcct
    25021 ctgaacaatc ctacatccta accgaagaaa actgggacag cattccagcc atgattggga
    25081 ttacagacac agacctcaaa gagatttttg gaaaatagta catcagaaaa cccaccaatt
    25141 caggtgggtt ttctgtttat taagattatt ttactgttgc tgtgcttgtg atcaattcaa
    25201 cagctttttt gatagtgata tcatgtttca acatgtcagc tgaaagcaag ttttgaactt
    25261 gtgcaacttc catgttgtag tctgctgcca attgctcaac ttctttttgg atttcttctt
    25321 ctgaagcatc aaatccttca gctttggcaa ctgcttcgat aacaaggtta gtcttagtac
    25381 gtgactcagc ttctgcttgg tattggttgt gaaggtcttc ttgagtagtt ccagtgattt
    25441 ggaagtacat gtcagggttg atcccttgac gttgcaagtt cccaaggaat tcatttactg
    25501 aacggtgaac ttcttcatgg atcatttctt ctggaagttc tacgatttca gcgttttcta
    25561 cagctgtatc aattgctgca ccttcaactg catctttgta agcttcttct ttagcagcag
    25621 ccaattcttt gcggtatttt tctttcaagt cagcaagtgt ttcaacttct tcatcaatgt
    25681 cttttgcaag ttcatcgtca agagctggaa cttctttagc ttttacttcg tggatagttg
    25741 tcacgaattt agcttcttta cctgcaaggt cttctgcttg gtagtcttct gggaatgtta
    25801 cgataacatc aacggtttcg ccagctgagt gacctaccaa ttggtcttcg aaaccaggga
    25861 tgaattgacc tgaaccaagt ccaagtgaga agttttcacc ttttccaccg tcaaattcaa
    25921 caccgtcgat agaaccaacg aagtcgatca caacagtgtc gccgttttca gcagcagctt
    25981 ccttgataac caattcagcc aggttgttgc gttcgcgttc gatacgctct tcaacatcag
    26041 cgtcagttac ttctttttct acatcaactg atacttcaag gtttttgtag tcacccaatt
    26101 ttacttcagg ttttgtaacg acttcagcag cgataaccca gtcttgacct ttttccattg
    26161 aagttacgtc aatttttggt tgggcaacca cttcaagacc agcttctttt acagctgctt
    26221 cataagcgtt tggcaaaaga gcgttcataa cgtcttggta aagtgattct tcaccaaatt
    26281 ttttatcgaa gataggacgt ggaaggtgac ctttacggaa acctggaaca ttaagagatt
    26341 tcttcactga cttgaagaca cggtccaatt ctggtttgat ttggtcttga gagatagtga
    26401 aagtcaagac accacggttt gtttctttgt tttcaaatga tacagacatt ctgtcatttc
    26461 tccttaaaat tttttaaata cagtctatta taacattttc tataaataaa atctagacta
    26521 atgcagccaa ttatagacaa caagcctttt tcctaactaa aacactcata aagtatagac
    26581 aattttagac tactttggat atcttttggt tagtcatttt ccaaaactaa tttatctaat
    26641 ttttca
//
LOCUS       DAVLGK010000032        26103 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLGK010000032 DAVLGK010000000
VERSION     DAVLGK010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26103
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.032"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            1..1001
                     /locus_tag="VXE01_001458"
                     /pseudo
     CDS             1..1001
                     /locus_tag="VXE01_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1044..1685)
                     /gene="plsY"
                     /locus_tag="VXE01_001459"
     CDS             complement(1044..1685)
                     /gene="plsY"
                     /locus_tag="VXE01_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV0750349.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDYLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1821..3764
                     /gene="parE"
                     /locus_tag="VXE01_001460"
     CDS             1821..3764
                     /gene="parE"
                     /locus_tag="VXE01_001460"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV0750350.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            4184..6655
                     /gene="parC"
                     /locus_tag="VXE01_001461"
     CDS             4184..6655
                     /gene="parC"
                     /locus_tag="VXE01_001461"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV0750351.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDVAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6787..7809
                     /locus_tag="VXE01_001462"
     CDS             6787..7809
                     /locus_tag="VXE01_001462"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV0750352.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7865..8569
                     /locus_tag="VXE01_001463"
     CDS             7865..8569
                     /locus_tag="VXE01_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0750353.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8634..9323
                     /locus_tag="VXE01_001464"
     CDS             8634..9323
                     /locus_tag="VXE01_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV0750354.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            9320..10243
                     /locus_tag="VXE01_001465"
     CDS             9320..10243
                     /locus_tag="VXE01_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV0750355.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            10258..10902
                     /gene="pcp"
                     /locus_tag="VXE01_001466"
     CDS             10258..10902
                     /gene="pcp"
                     /locus_tag="VXE01_001466"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0750356.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            11070..11300
                     /locus_tag="VXE01_001467"
     CDS             11070..11300
                     /locus_tag="VXE01_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV0750357.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            11350..11430
                     /locus_tag="VXE01_001468"
     tRNA            11350..11430
                     /locus_tag="VXE01_001468"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11384..11386,aa:Tyr,seq:gta)
     gene            11440..11511
                     /locus_tag="VXE01_001469"
     tRNA            11440..11511
                     /locus_tag="VXE01_001469"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11472..11474,aa:Gln,seq:ttg)
     gene            11673..12875
                     /gene="rpsA"
                     /locus_tag="VXE01_001470"
     CDS             11673..12875
                     /gene="rpsA"
                     /locus_tag="VXE01_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV0750358.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(12960..14262)
                     /locus_tag="VXE01_001471"
                     /pseudo
     CDS             complement(12960..14262)
                     /locus_tag="VXE01_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            14455..14952
                     /locus_tag="VXE01_001472"
     CDS             14455..14952
                     /locus_tag="VXE01_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV0750359.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            14952..16607
                     /gene="dnaX"
                     /locus_tag="VXE01_001473"
     CDS             14952..16607
                     /gene="dnaX"
                     /locus_tag="VXE01_001473"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV0750360.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARFKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            16635..16829
                     /locus_tag="VXE01_001474"
     CDS             16635..16829
                     /locus_tag="VXE01_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV0750361.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            16979..17749
                     /gene="sufC"
                     /locus_tag="VXE01_001475"
     CDS             16979..17749
                     /gene="sufC"
                     /locus_tag="VXE01_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV0750362.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEGDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            17777..19039
                     /gene="sufD"
                     /locus_tag="VXE01_001476"
     CDS             17777..19039
                     /gene="sufD"
                     /locus_tag="VXE01_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV0750363.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            19050..20276
                     /locus_tag="VXE01_001477"
     CDS             19050..20276
                     /locus_tag="VXE01_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0750364.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            20263..20703
                     /locus_tag="VXE01_001478"
     CDS             20263..20703
                     /locus_tag="VXE01_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV0750365.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            20757..22169
                     /gene="sufB"
                     /locus_tag="VXE01_001479"
     CDS             20757..22169
                     /gene="sufB"
                     /locus_tag="VXE01_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV0750366.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(22400..23641)
                     /locus_tag="VXE01_001480"
     CDS             complement(22400..23641)
                     /locus_tag="VXE01_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV0750367.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            23744..24853
                     /locus_tag="VXE01_001481"
     CDS             23744..24853
                     /locus_tag="VXE01_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0750368.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            25387..25734
                     /gene="ssrA"
                     /locus_tag="VXE01_001482"
     tmRNA           25387..25734
                     /gene="ssrA"
                     /locus_tag="VXE01_001482"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(25917..26004)
                     /locus_tag="VXE01_001483"
     tRNA            complement(25917..26004)
                     /locus_tag="VXE01_001483"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(25968..25970),aa:Ser,seq:gga)
BASE COUNT         7973 a         4638 c         5723 g         7769 t
ORIGIN      
        1 atgggacgta atccaaaaac gagacctgaa gagaggacag aattagaacg tcttcaatca
       61 gaaaatgagt acctgagagc ggagaatgcc atcctaaaaa agttaagaga actccgattg
      121 aaggaggaaa aagagaaaga agaaagacag aaattgttca agaattaatg actgagtttt
      181 cgttagatct tcttctaaaa tccattaaac tagctcgttc gacctactac tatcacttga
      241 aacagctaga caaaacagat aaggaccaag agcttaaagc tgaaattcaa tccattttta
      301 tcgaacacaa gggaaattat gcttatcgct gtattcattt agaactaaga aatcgtggtt
      361 atctggtaaa tcataaaaga gttcaaggct tgataaaagt actcaattta caagctaaaa
      421 tgcgacagaa acgaaaatat tcttctcata aaggagacgt tggcaagaag gcagagaatc
      481 tcattcaagg ccaatttgaa ggctctaaaa caatggaaaa gtgctacaca gatgtgacag
      541 aatttgccat tccagcaagt actcaaaagc tttacttatc accagtttta gatggcttta
      601 atagcgaaat tattgctttt aatctttcaa cttcgcccaa cttagaacaa gtgaagagta
      661 tgttagaaca ggcctttaca gagaaatact atgagaatat gattctccat agtgaccaag
      721 gctggcaata ccgacacgat tcttatcatc ggttcctaga gagtaaggga gttcaagcat
      781 ccatgtcacg taagggtaac agcccagaca atggtatgat ggagtccttc tttgggattc
      841 tgaaatcgga aatgttttac ggttatgaga agtcgtttca gtcgcttaag caattggaac
      901 aagccattat agactatatt gattactaca acaataaacg aattaaggta aaactaaaag
      961 gacttagccc tgtgcaatac agaactaaat ccttcggata aattaattgt ctaactgttt
     1021 gggggcagta cagaactggc gttttatttt ttaggatctt gatgggttag gttcaatccc
     1081 caagggacca aattttcagt tttatttttg atacgagcta tattgtcctt atgacgaatg
     1141 ataatcaaac tagcaagtgc taagataata gcgatgaaga gatagtcata gttactcagg
     1201 ataaaaccaa aaagtggaaa gagcagaacc ccgataacag ccgcgatcga tgctgtgaca
     1261 ctagacagtg aaatcatact gccaagatag agagctccaa agaagataat cgcaaggtag
     1321 agacagaaga taggcgcaaa tccgaaaatc actccagcac tggttgcgac agccttacca
     1381 cctttaaatc ctgcaaagat agggaaggta tggccgataa cagccaaaag tccaaagatg
     1441 agaggagaaa cgccttgtag atgaaaaata atcggaagca gcgttgctag ggttcctttg
     1501 aaaaagtcaa tcacaaaggt tgccatacca gctttcttac ctaaaatgcg gaaggtgttg
     1561 gtcgttccag tgttaccaga accatgctcg cgtagattga tttgaaagaa tacttgtcca
     1621 atccagagac cagatggaat cgaacccagc agataggcta ggattaataa aactattgta
     1681 atcatactcc tattatatca tgaattggga aagaaaagca gagaatctct gctgaaattg
     1741 tcacatcgga gaaagaaaaa ttttgcaaaa tccttggaaa acctgtagaa tagtaaagat
     1801 gaacgaatag gaggttcctt gtgtcaaaaa aggaaatcaa tattaacaat tataatgatg
     1861 atgctattca ggtgctagaa gggttggatg cggtccgaaa acgtccaggg atgtatattg
     1921 gatcgaccga tggcgctggt cttcatcacc tagtttggga aatcgttgat aatgcagtcg
     1981 atgaagcctt gtctgggttt ggtgatcgta ttgatgtaac tatcaataaa gacggtagtc
     2041 taacggttca agaccatgga cgtgggatgc cgacaggtat gcacgctatg ggaattccaa
     2101 ctgttgaagt tatctttacc attcttcatg ccggagggaa attcggtcaa ggtggctata
     2161 agacatcagg tggacttcac ggagtgggtt cttccgttgt taacgccctt tctagctggt
     2221 tagaagttga aattacccgt gatggcgcag tttacaagca acgttttgaa aatggtggaa
     2281 aacctgtcac gactttgaag aaaatcggta cagcacccaa gtctaaaaca ggcaccaaag
     2341 ttacttttat gcctgacgcg actatctttt ctacgacaga tttcaagtac aataccattt
     2401 cagagcgcct taatgaatca gcctttctct tgaaaaatgt gaccttgtct ttaacggaca
     2461 agcgaacaga tgaagcgatt gagttccact atgagaatgg agtacaagat tttgtttctt
     2521 atctcaacga agataaggaa atcttgacgc cagttcttta ctttgaaggg gaagacaatg
     2581 gttttcaagt ggaagtagcc ctccagtaca atgacggatt ctcagataac attctatcct
     2641 ttgtcaataa cgttcgcacc aaggacggtg gaacgcacga gacaggactc aagtctgcca
     2701 ttaccaaggt catgaatgac tatgcacgta aaacaggtct tctcaaggaa aaagataaaa
     2761 accttgaagg ttcagactat cgtgagggac tagcggccgt tctttctatc ttagttcctg
     2821 aagaacactt gcagtttgaa ggacagacca aggataaact aggaagcccc ctagctcgcc
     2881 cagttgtgga tggaatagtg gctgataagt tgaccttttt ccttatggaa aatggggaat
     2941 tagcttctaa cctcatccgc aaggctatca aggcccgtga tgctcgtgaa gcagcacgta
     3001 aggcgcgtga tgagagccga aatgggaaga aaaacaagaa agataagggc ttgttgtctg
     3061 ggaaattgac cccagcccaa tctaagaatc ctgctaagaa tgaactctat ctagttgagg
     3121 gggactctgc cggtggttct gccaaacaag gtcgtgaccg caagttccag gctattctac
     3181 ctcttcgtgg taaggttgtc aatacagcca aggccaagat ggcggatatc ctcaaaaatg
     3241 aagagatcaa taccatgatt tataccattg gtgcgggtgt tggagcagac ttctctattg
     3301 aagatgccaa ctatgataag atcattatca tgaccgatgc ggataccgac ggtgcccata
     3361 tccagacctt gctcttgaca tttttctacc gttacatgcg tccgctagtc gaggcaggtc
     3421 atgtctatat tgccctccca cctctttaca agatgtccaa aggtaaaggc aagaaagaag
     3481 aagtggccta cgcttggacg gacggagaac tagaagaact ccgtaaacag ttcggtaaag
     3541 gcgctaccct ccaacgatac aaaggacttg gtgagatgaa tgcggaccag ctctgggaaa
     3601 caaccatgaa cccagaaaca cgtaccctca tccgtgtcac aattgaagat ttagcgcgcg
     3661 ccgaacgccg cgtcaatgtt ctcatgggag ataaggtaga accacgccgt aaatggattg
     3721 aagataatgt caagtttacg ctagaagaag cgacagtgtt ttaatgaaag aaaataatat
     3781 gttagtaaac tggaaattag agtcggatgt gaatgactat gtaaaaaagc agtttgaaaa
     3841 tcttggtttg aaaaaattgc aggattatta atgaagaatc ttctatgagt gcttatctca
     3901 aagaggcgtt taagggagcg gctaagacac aaactaagac taattttgga aaaccagatt
     3961 ttcatattga aaaatacaaa caggatagtt tggttactta tcgtaactga acacgggacg
     4021 aattcccgta aaatatcttt tactgcataa aaacctactc tacattcttt gaaaggagtt
     4081 gaacacgccc tagatactgt gtgaaaaaga taaattctct tgtgagtttg cttacttcaa
     4141 gaattttcta ttttcacttg gtattttatg ggctttgtat cttatgtcta acattcaaaa
     4201 catgtccctg gaggacatca tgggagagcg ctttggtcgc tactccaagt acattattca
     4261 agaccgggct ttgccagata ttcgtgatgg gttgaagccg gttcagcgcc gtattcttta
     4321 ttctatgaat aaggatagca atacttttga caagagctac cgtaagtcgg ccaagtcagt
     4381 cgggaacatc atggggaatt tccacccaca cggggattct tctatctatg atgccatggt
     4441 tcgtatgtca cagaactgga aaaatcgtga gattctagtt gaaatgcacg gtaataacgg
     4501 ttctatggac ggagatcctc ctgcggctat gcgttatact gaggcacgtt tgtctgaaat
     4561 tgcaggctac cttcttcagg atatcgagaa aaagacagtt ccttttgcat ggaactttga
     4621 cgatacggag aaagaaccaa cggtcttgcc agcagccttt ccaaacctct tggtcaatgg
     4681 ttcgactggg atttcggctg gttatgccac agacattcct ccccataatt tagctgaggt
     4741 catagatgtt gcagtttaca tgattgacca cccaactgca aagattgata aactcatgga
     4801 attcttgcct ggaccagact tccctacagg ggctattatt cagggtcgtg atgaaatcaa
     4861 gaaagcttat gagactggga aagggcgcgt ggttgttcgt tccaagactg aaattgaaaa
     4921 gctaaaaggt ggtaaggaac aaatcgttat tactgagatt ccttatgaaa tcaataaggc
     4981 caatctagtc aagaaaatcg atgatgttcg tgttaataac aaggtagctg gaattgctga
     5041 ggttcgtgat gagtctgacc gtgatggtct tcgtatcgct atcgaactta agaaagacgc
     5101 taatactgag cttgttctca actacttatt taagtacacc gacctacaaa tcaactacaa
     5161 ctttaatatg gtggcgattg acaatttcac acctcgtcag gttgggattg ttccaatcct
     5221 gtctagctac atcgctcacc gtcgagaagt gattttggcg cgttcacgct ttgacaaaga
     5281 aaaggctgag aaacgtctcc atatcgtcga aggtttgatt cgtgtgattt cgattttgga
     5341 tgaagtcatt gctcttatcc gtgcttctga gaataaggcg gacgccaagg aaaacctcaa
     5401 agttagctat gattttacgg aagaacaggc tgaggctatc gtaactttgc aactgtaccg
     5461 tttgaccaat accgatgtgg ttgtcttgca ggaagaagaa gcagagcttc gtgagaagat
     5521 tgctatgctg gcggctatta tcggtgatga aaggactatg tacaatctca tgaagaaaga
     5581 acttcgtgag gtcaagaaga aatttgcaac tcctcgtttg agttctttag aagatactgc
     5641 gaaagcaatt gagattgata cagctagtct tatcgctgag gaagatacct acgtcagcgt
     5701 gaccaaggca ggttacatca agcgtaccag tccacgttcc tttgcggctt ccaccttgga
     5761 agaaattggc aagcgtgatg atgaccgttt gatttttgtt caatctgcca agacaaccca
     5821 gcacctcttg atgttcacaa gtcttggaaa tgtcatctac agaccaatcc atgagttggc
     5881 agatattcgt tggaaggaca tcggagagca tctgagccaa accatcacaa actttgaaac
     5941 gaatgaagaa atcctttatg tggaagtact ggatcagttt gacgatgcga caacctactt
     6001 tgcagcgact cgccttggtc aaatcaaacg ggtagagcga aaagaattta ctccatggcg
     6061 gacctataga tctaagtctg tcaagtatgc taagctcaaa gacgatacag atcagattgt
     6121 agcagtggct ccgattaaac tagatgatgt tgtcttggtt agtcaaaatg gttatgccct
     6181 gcgtttcaat atcgaagagg ttccggttgt cggtgctaag gcagcaggtg tcaaggctat
     6241 gaatttgaaa gaagatgatg tcctccaatc tggctttatc tgtaatactt cgtccttcta
     6301 cctcttgacc cagcgtggaa gcttgaaacg tgtttccatt gaggaaattc tagcaaccag
     6361 ccgtgccaaa cgaggattac aagtcttgcg tgagttgaaa aacaaaccgc atcgtgtctt
     6421 cttggcagga gcagttgcag agcaaggatt tgttggcgat ttcttcagta cggaagtgga
     6481 tgtgaacgac caaactctgc ttgtccaatc caataaagga acaatctatg aaagccgatt
     6541 gcaagacttg aacttgtcag aacgcactag caatggaagc ttcatttctg acacgatttc
     6601 agatgaagaa gtttttgacg cttatcttca ggaagtagtt actgaagata aataagtgaa
     6661 atgaagaatc agttctaaga gctggttttt attggagaaa ttttctgaaa attacaaaat
     6721 atacttgcta ttttagaaaa atagtgtaga atataagaaa taggttttta gaataaggag
     6781 tggaatatga cagtaacgat tgattgggaa aacctcggtt tttcctatat gaaattacct
     6841 tatcgctatc ttgctcattt caaaaatgga caatgggatc aaggagagct tacagaggat
     6901 gcaactttgc atatttcaga gtcttctcca agtcttcact atggacaaca agcatttgaa
     6961 ggtttgaaag cttatcgtac taaggatggc agtgttcaac tgttccgtcc tgatgaaaat
     7021 gctaaacgcc tgcaacgtac atgtgaccgt ctcttgatgc cacaagttcc gacagacatg
     7081 tttgtagaag cttgtaaagc agttgtccgt gcgaatgaag aatacgtacc accatacgga
     7141 ataggtggaa ccttatatct tcgccctctt ttgattggtg tcggagatat tatcggggta
     7201 aaaccggcag aagaatacat tttcaccatc tttgctatgc cagttggaaa ttactttaaa
     7261 ggtggtttgg tcccaaccaa cttcttgatt caggatgagt acgaccgtgc agcaccaaat
     7321 ggtacaggtg cggctaaggt tggtggaaac tatgctgcaa gtctcttacc aggaaaaatg
     7381 gccaagtcac gtcatttctc agatgttatc tatctggacc catcaactca tacaaagatt
     7441 gaagaagtcg gatcagctaa cttctttgga attacagctg ataatgaatt tgtaacacca
     7501 ttgagtccat ctatcttgcc atctattacc aagtattcct tgctttattt ggcagaacat
     7561 cgcttgggat taactcctat tgagggtgat gttccaattg ataatcttga ccgttttgta
     7621 gaggcaggtg cctgtggtac agcagcggtt atttctccaa ttggaggtat tcaacatggt
     7681 gatgatttcc atgtattcta tagtgaaaca gaagtaggtc ctgtgacgcg taaattatat
     7741 aatgaattga cgggtattca gtttggcgat attgaagcgc cagaaggttg gattgtaaaa
     7801 gtagattaaa ataaaccaaa ggagattttt tatgaaatag aaaaagtggc tcttaacagc
     7861 aggagtggtc ctgagcacgt cagctatttt agtggcttgt ggaaaaactg ataaagaagc
     7921 agatgcaccg acaacatttt cttatgtcta tgcagtagat ccagcatcat tgggctacag
     7981 tatagcgact cgaacatcga ggacagacgt tattggaaat gttattgatg gtttgatgga
     8041 aaatgataaa tacggcaatg ttgctccttc tcaaaaagac tatgatttga acagtacagg
     8101 atgggctcca agctatcaag atccagcgtc ttacttgaat attatggatc caaaatctgg
     8161 ttctgccatg aaacaccttg gcattacgaa aggaaaagat aaggatgttg tagctaaacc
     8221 tggtttggat aaatataaga aattgttaga agatgctgtt tctgagacca ctgacctaga
     8281 gaagagatat gaaaaatatg ccaaagctca agcttggtcg acagatagtt cattattgat
     8341 gccaacagct tcatctggtg gttctccagt tgtaagtaac gtagtaccat tctcaaaacc
     8401 atactcacaa gttggtatta agggggaacc atatatcttt aaaggaatga aattgcaaaa
     8461 agatattgtt acaacaaaag aatataacga ggtttttaaa aaatggcaaa aagaaaaatt
     8521 ggaatccaat agcaaatacc aaaaagaact agaaaaatac attaaataag gaatggtatt
     8581 gatcttgata aaatttttaa aatactgtca ttttgaatat aaaggagttt gatatggagt
     8641 ggattagatt aataggaata gcaatcattg ttgtgggttt tattttaaaa tttgatacaa
     8701 ttgcaacagt agtcttagct ggtttggtta cagctttagt ttcaggtgtt tctctcgttg
     8761 aatttttgga gattttggga aaagaattta gcaatcagcg agtgctcacg atttttatgg
     8821 ttaccttgcc tcttgtgggg ctgtcagaaa cctttggact caagcaacga tcaatcgatt
     8881 tgattcgaaa gattaaaggt ctgacagttg gaaacttcta tacagtttat ttctttattc
     8941 gagagttagc tggtttcttt tcaattcgtc taggaggaca ccctcagttt gtcagacctt
     9001 tggttcaacc tatgggagaa gcagctgcag agtctcaatt aggtagaaag ttaacagagg
     9061 ttgaagatga gacaataaaa gcgcgtgcgg ctgcgaatga aaattttgga aatttctttg
     9121 ctcaaaatac gtttgtaggt gctgggggag tcctcttgat agggggaaca ttagatcagt
     9181 taggctatga aagcaattat gcagggattg cttctacatc tattattgtt gctgttataa
     9241 cacttattgt agtggggatt tacaattatt tatttgataa aaaattgata tcaaaaaaga
     9301 ctaggggagg agaacaaaaa tgacagagtt ggcaaagcaa ctattagagt tgacctatat
     9361 tgtgattggt tgtcaatttc tccatacagc ctattgtagt tataaagata aaacaaaccc
     9421 agttcgactt gggacatctg cattttggac tctattgtct attacgttta taggtggttc
     9481 ctatatgcca aatatgagta ttggtattat tgtaatccta ttatcgctgt taacattgtt
     9541 taagcaagtc cgtatcggaa ccttgccatc cttagatgaa atgaaagcca atattgaatc
     9601 taacaggttg aaaaataaaa tttttattcc agttatgctg atggcaatac ttgcgttggt
     9661 cttagcgcaa atgattccag aatttagcaa gatttcgatt agccttgccg ccttgtttgc
     9721 tacaatttct gttcttgtga ttaccaatag tcaccctaag agtctgttat cagaaaataa
     9781 tcgaatgact cagcaagttt caacaagtgg gattgttcct caattattag gggctttggg
     9841 ggctattttt actgtagcag gtgttggtga tgttatctct catctgatta gcggtattgt
     9901 tccttcagat agtcgcttta taggagtttt ggcttatgtt cttggaatgg ttctattcac
     9961 aatgattatg ggaaatgctt ttgcagcatt caccgttatt acagcaggtg ttggagttcc
    10021 ctttgtattt gctctgggag ctaatccaat tgtggctggt gctcttgcca tgacagcagg
    10081 ttattgtggg accttattga ccccaatggc tgctaatttt aacgctctac cagcagcatt
    10141 gatggatatg aaagatcaga atggcgttat aaaggctcaa gcaggtgttg ctctagtaat
    10201 gattgttatt cacatattct taatgtactt tctcgcattt tagtaaagga aaataaaatg
    10261 aaaatattgg ttacaggttt taatcctttt ggaggtgaaa agattaatcc agctttggag
    10321 gctgtaaaat tattaccatc tgagattaat ggggctgaag ttcgctgggt agaaattcca
    10381 acggtttttt ataagtcgtc agaagtttta gaggcagaaa tattacgata tcaaccagat
    10441 gctgtacttt gtattggaca agcaggcggc aggaccggct taacacctga acgagtggct
    10501 attaatcaag atgatgctcg catacctgat aacgaaggca atcaaccaat tgatacaccg
    10561 attcgtattg atggagcatc ggcctatttt agtagtttac ctatcaaagc gatggtacaa
    10621 gctatcaaaa aacagggact tccggcagtt gtatccaata gtgcaggaac ctttgtttgc
    10681 aatcatttga tgtaccaagc tctttattta gtggataaaa aattccctaa tatgagagca
    10741 ggtttcatgc atattccata tatgatggaa caagtagtaa ataagccgaa tactgcagga
    10801 atgagtctat gtgatattgt aagaggcata gaggtagcta ttgaagctat tgtagactac
    10861 aaagataagg atttgcagtt agtaggcggt gagactcact gataacctaa aaaggatagt
    10921 caattatgct tgtttactaa ctattaacta tgctaaatca attgaggttg tttacataaa
    10981 actctatatc agagaagcct gatatagagt tttttcttgc tagttttagg attttcttgt
    11041 aaaatagaaa aagtgaagag aggtatgaaa tgagcaagaa agataaaaaa atcgaaattc
    11101 aagtagcgga tgccaaagtt aatgttggta aagacagttt tgaaggttat acattgacta
    11161 tcggtaaaaa agttatcgga gaaattgccg aattagacgg acaatttgcc attataaaga
    11221 atgggaatgt cgatagtttt tataaaaaat tggaaaaagc tgtggaaatt ttgattgaaa
    11281 attataattt agcaaaataa gtcttgtttt tttgaaattt tcatgatata atagtccatg
    11341 ttgattgtag gagagatagc gaagaggcta aacgcggcgg actgtaaatc cgctccttcg
    11401 ggttcggggg ttcgaatccc tctctctcca tttcattaat ggggtatagc caagcggtaa
    11461 ggcaagggac tttgactccc tcatgcgttg gttcgaatcc agctacccca gttcttaggt
    11521 aataatcaag atagaaagca aaatatctta gggtatttta tttttataat tgaaagacgt
    11581 gaatgatatg aacatgtcct tgcgggtgct taggaaaaaa attataagta tgtcaagttt
    11641 aagaaaaact tgattgttgg aggatttttt agatgaacga atttgaagat ttgctaaata
    11701 gcgttagtca agttgagact ggtgatgttg ttagtgctga agtattgaca gttgatgcga
    11761 ctcaagctaa cgttgcaatc tctggaactg gtgttgaagg tgtcttgact cttcgcgaat
    11821 tgacaaacga tcgtgatgca gatatcaatg actttgttaa agtaggagaa gtattggatg
    11881 ttcttgtact tcgtcaagta gttggtaaag atactgatac agttacatac cttgtatcta
    11941 aaaaacgcct tgaagctcgc aaagcatggg acaaacttgt tggtcgcgaa gaagaagttg
    12001 ttactgttaa aggaacgcgt gccgttaaag gtggactttc agtagaattt gaaggtgttc
    12061 gtggatttat cccagcttca atgttggata ctcgtttcgt acgtaacgct gagcgttttg
    12121 taggtcaaga atttgatact aaaatcaaag aagttaacgc taaagaaaac cgcttcatcc
    12181 tttcacgtcg tgaagttgtt gaagcagcta ctgcagcagc tcgcgctgaa gtattcggta
    12241 aattggctgt tggtgatgtt gtgactggta aagttgctcg tatcacaagc ttcggcgctt
    12301 tcatcgacct tggtggtgtt gacggattgg ttcacttgac tgaattgtca catgaacgta
    12361 acgtatcacc aaaatcagtt gtaactgttg gtgaagaaat tgaagtgaaa atccttgatc
    12421 ttaacgaaga agaaggacgt gtatcacttt cacttaaagc aacagtacca ggaccatggg
    12481 atggcgttga gcaaaaattg gctaaaggtg atgtagtaga aggaacagtt aaacgtttga
    12541 ctgacttcgg tgcatttgtt gaagtattgc caggtatcga tggacttgtt cacgtatcac
    12601 aaatttcaca caaacggatt gaaaatccaa aagaagctct taaagttggt caagaagttc
    12661 aagttaaagt tcttgaagtt aacgcagatg cagaacgcgt atcactttct attaaagctc
    12721 ttgaagaacg tccagcccaa gaagaaggac aaaaagaaga aaaacgtgct gctcgtccac
    12781 gtcgtccaag acgtcaagaa aagcgtgatt tcgaacttcc agaaacacaa acaggatttt
    12841 caatggctga tttgtttggt gatatcgaac tttaatcaaa ttgaaaattc acaaaatcct
    12901 ttgtttacta aacaagggat ttttcggctc tttgtcaact gtagtgggtt gaaaaaaagc
    12961 taagcttgag aaaggacaaa ttttgtcctt tcttttttga tgttcagagc gataaaaatc
    13021 cgttttttga agttttcaaa gttccgaaaa ccaaaggcat tgcgtttgat aagtttgatg
    13081 agattattgg tcgcttccaa tttggcgttt gaatagggta gttgaagggc gttgacgatt
    13141 ttctctttgt tctttagaaa ggttttaaag acagtctgaa aaagaggatg aacctgctta
    13201 agattgtcct caataagtcc gaaaaatttc tctggttcct tattatagag ctgatagtgg
    13261 tgtttcaagt cttctgaata gctcaaaagc ttgtttaaaa tctctttatt ggttaagtac
    13321 atacgaaaag taggacgata aaatcgctta tcactcagtt tacggctatc ctgttgaatg
    13381 agtttccagt agcgcttgat agccttgtat tcatgagact ttcgatgaaa ctgattcatg
    13441 atttggacat gcacacgact catagcacgg ctaagatgtt gtacaatatg aaagcgatca
    13501 agaacgattt tagcattcgg gagtgaaaca gtctgggaga ctgtttcagc ctgagcctag
    13561 aaatttgaaa gcgaagttgt ctagctaagt catagtaagg actaaacata tccatagtaa
    13621 tgattttcac ttgacaacga acggctctat catatttaag aaagtgatct cggatgatag
    13681 cttgtgttct accttcaaga acagtgatga tattgagctt ttcaaaatct tgcgcaataa
    13741 agctcatctc catcttccga ttgaaacagt cactccccgg actgtttcaa cgtcccaaga
    13801 cataatctca ggcagatttc taaaattaca ctcaaagtgg aagtcattga gctttcgaat
    13861 gacagttgaa gttgagatgg aaagctgatg ggcaatatcg gtcatagaaa tcttttcaat
    13921 taacttttga gcaatctttt ggttgatgat acgagggatt tggtgattct tcttgacgat
    13981 agaagtttca gcgaccatca tttttgaaca gtgatagcac ttgaatcgac gctttctaag
    14041 gagaattcta gtaggcatac cagtcgtttc aagataagga attttagacg gtttttgaaa
    14101 gtcatgtttc ttcatttgac ttccgcactc agggcaagat ggggtgtcat aatccagtct
    14161 agcgatgatt tccttgtgtg tatccttatt gatgatgtct aaaatctgga tattagggtc
    14221 tttaatgtct agtaattttg tgataaaatg taattgttct atatgattct ttctaatgag
    14281 ttgttttgtt gcttttcatt ataggtcata tgggactttt tttctacaca aaataggctc
    14341 cataatatcc ataggggatt tacccactac aaatattata gagcccaaaa tcctttgttt
    14401 actaaacaag ggatttttct tttgtctctg ctcctttttt gatataatag ttctatgtta
    14461 aaatcagaaa aacaatcacg ttatcaaatg ttaaatgaag aattgtcctt cctattggaa
    14521 ggcgaaacca atgttttggc taatctttcc aacgccagtg ctctcataaa atcacgtttt
    14581 cctaataccg tatttgcagg cttttatttg ttcgatggaa aggaattggt tttaggcccc
    14641 ttccaaggag gtgtttcctg catccgtatt gcactaggca agggtgtttg tggtgaggca
    14701 gctcactttc aggaaactgt tattgttgga gatgtgacga cctatctcaa ctatatttct
    14761 tgtgatagtc tagctaaaag tgaaattgtg gtgccgatga tgaagaatgg tcagttactt
    14821 ggagttctgg atctggattc ttcagagatt gaggattacg atgctatgga tcgagattat
    14881 ttggaacaat ttgtcgctat tttgcttgaa aagacaacat gggactttac gatgtttgag
    14941 gaaaaatctt aatgtatcaa gcactttatc gaaaatatag aagtcaaaac ttctcccagt
    15001 tagttggtca agaagttgtg gctaagactc ttaaacaagc ggtggagcaa gagaaaataa
    15061 gtcacgctta tcttttttct ggtcctcgtg gaacgggaaa aaccagtgtt gctaaaatct
    15121 ttgccaaggc tatgaactgt cccaatcaag tgggtggcga accttgcaat aactgctata
    15181 tttgtcaagc agtgacggac ggtagtttag aagatgtcat tgaaatggat gcagcttcta
    15241 ataatggggt agatgaaatt cgcgaaattc gtgataaatc tacctatgcg cctagccttg
    15301 ctcgttataa ggtttatatc atagatgagg ttcacatgct gtctacaggg gcttttaatg
    15361 ccctcctaaa gacgctggaa gaaccaacac agaatgtagt ctttattttg gccactactg
    15421 aattgcacaa gattcctgct actattctat cccgtgtgca acgttttgag tttaaatcaa
    15481 ttaagacaca ggatattaag gaacatattc actatatctt agaaaaagaa aatatcagtt
    15541 ctgaaccaga ggctgtggaa atcattgcca ggcgggcgga aggtggaatg cgggacgcct
    15601 tgtctatttt ggatcaagcc ctgagtttga cacagggaaa tgagctgacg actgctatct
    15661 ctgaagaaat tactggcacc attagcctat cagccttgga tgattatgtg gcggccttgt
    15721 ctcaacagga tgttcccaaa gctttgtctt gcttgaatct tctttttgac aatggtaaga
    15781 gcatgactcg ttttgtgacc gatcttttgc actatttaag agacttgtta attgttcaaa
    15841 cagggggaga aaatactcat catagttcag tctttgtaga aaatttggca cttcctcaaa
    15901 aaaatctgtt tgaaatgatt cgcttagcaa cagtgagttt agcagatatt aagtctagtt
    15961 tgcagcccaa gatttatgct gaaatgatga ccgtccgttt ggcggaaatc aagcccgaac
    16021 cagctctatc aggagcggtt gaaaatgaaa ttgctacgct gagacaggaa gttgcccgtt
    16081 tcaaacaaga gctttctaat gtaggtgcgg ttcctaaaca agttgcacca gctcctagtc
    16141 gaccagctac gggcaaaaca gtctatcgtg tcgatcgcaa taaagtgcaa tctatcttac
    16201 aagaggccgt cgaaaatcct gatttagcac gtcaaaatct aattcgtttg cagaatgcct
    16261 ggggagaggt aattgaaagt ctaggtgggc cggacaaggc tctgctagtt ggttctcaac
    16321 cggttgctgc caatgaacac catgctattc ttgcttttga gtctaacttc aatgctggtc
    16381 aaactatgaa acgagacaat ctcaatacca tgtttggtaa tatcctcagt caggcggcag
    16441 gtttttcacc tgagatttta gctatttcca tggaggaatg gaaagaagtt cgcgcagcct
    16501 tttcagccaa agccaaatct tctcaaactg aaaaagaagt agaagaaagc ctgattccag
    16561 aaggatttga atttttggct gataaagtga aggtagagga agactaaaga aagatttcat
    16621 gatacaataa gtttatgaat aaacaacaat ttattattat ggcgctgttt acagctgctg
    16681 agacctattt tttcaatgaa gcctggatga ctggccgcta tattatggca gccttttggg
    16741 caattttact ctttagaaat ttccgagtca gttatgtgat gggcaaaatc gttgatgtca
    16801 tcgatcagca ttttaatagg aaagactagc cctcagcttc cagacaaaat caaagccttt
    16861 taggcttttt tttgttatac tagaaaagta tatttataga atttttgctc tatttctggg
    16921 gaaatcagac gtttttctag taagtactgt aaaagttttg aaaaagaaag gaactatcat
    16981 gtcagtatta gagattaaag atcttcacgt tgagattgaa ggaaaagaaa ttttaaaagg
    17041 ggttaacctg accctgaaaa caggagaaat tgccgctatc atgggaccaa atggtacagg
    17101 taaatcgact ctttctgccg ctatcatggg aaatccaaac tatgaagtaa ctaaaggtga
    17161 agttttgttt gatggcgtaa acatccttga gttggaagtg gatgagcgtg cgcgtatggg
    17221 acttttcctt gctatgcaat acccatcaga aatccctgga attaccaatg ctgagtttct
    17281 tcgtgccgct atgaatgcgg gtaaagaagg tgatgagaag atttcagttc gtgagtttat
    17341 tactaagcta gatgaaaaaa tggaattgct caacatgaaa gaagaaatgg cagagcgtta
    17401 cctcaacgaa ggcttctctg gtggtgagaa aaaacgcaat gaaattcttc aacttttgat
    17461 gttggagcca acatttgctc ttttggacga gattgactca ggtcttgata ttgacgctct
    17521 taaagttgtg tctaaaggtg tcaatgccat gcgtggtgaa ggttttggtg ctatgatcat
    17581 cactcactac caacgtcttt tgaactatat cacacctgat gtggtacacg tgatgatgga
    17641 aggtcgtgtt gtcctttctg gtggtccaga attggctgcg cgtttggaac gtgaaggata
    17701 cgcaaaatta gctgaagaac ttggctacga ctacaaggaa gaattgtaat tccctcgtat
    17761 cttttaggag aagtaaatga ctagagaaaa tattaaactt ttttcagaaa tgcacgctga
    17821 accaagctgg ttggctgatc tccgtcaaaa agcttttgac aagattgaga ctttggaatt
    17881 accagttatt gagcgtgtca aattccaccg ttggaatctg ggtgatggaa cgattacaga
    17941 aaatgagcca tcagcaaatg ttccagattt cacagcttta gatcatcact tgaagttggt
    18001 gcaagtagga actcaaactg ttttcgaaca aactccagtt gagttagctg aacagggtgt
    18061 tgtcttcaca gactttcact cagctttaga agaaattcca gagctgatcg aagaattctt
    18121 catgtcatct gttaagtatg atgatgacaa gttggcggct taccacacag cttactttaa
    18181 cagtggtgct gtactctata ttccagataa cgtagaaatc acagagccaa ttgaaggaat
    18241 tttctaccaa gatagcgata gcaatgtgcc gtttaacaag catattatga ttatcgctgg
    18301 taaaaattct aagattagtt atctggagcg tttagagtca cgcggtgaag gaagtgacaa
    18361 agcaactgcc aatatcacag tggaagtgat tgcacgttct ggtgcgcaag tcaagtttgc
    18421 tgctattgac cgtctaggtg aaaacgtcac tgcctacatt agccgtcgtg gtaaattagg
    18481 caacgatgca agtattgact gggctatcgg tgtcatgaac gaaggaaatg tcgttgctga
    18541 ttttgatagt gacttgattg gtaatggtag ccatgctgac ctcaaggttg tagctctttc
    18601 aagtggtcgt caggtacaag ggattgatac tcgtgtaact aactatggct gcaactctat
    18661 cggaaatatc ctacaacatg gggttatcct tgaaaaagca actttgactt tcaatggtat
    18721 cggccacatc atcaagggtg ctaagggagc agatgcccaa caagagagcc gtgttctcat
    18781 gctttcagac caagcgcgtt cagatgctaa cccaattctt ttgattgatg aaaatgacgt
    18841 cactgcagga catgcagcct ctattggtca ggtagatcca gaagatatgt actacctcat
    18901 gagtcgtgga ttggataagg caactgcaga gcgtttggtt gttcgtggtt tccttggatc
    18961 tgttatcgtg gagattccag tcaaggaagt tcgtgatgaa atgattgcaa ctatcgaaga
    19021 gaaattgtca aaacgctaag gggaagccta tgttagatgt agaagcgatt cgcaaggatt
    19081 ttccaatttt agatcagatt gtcaatgatg aacctctggt ctatctggac aatgctgcga
    19141 cgacacaaaa accactagta gttctgaaag ctattaacag ttactatgag caggacaatg
    19201 ccaatgttca ccgtggtgtc cataccttag cggaacgagc gacagcttct tatgaagctg
    19261 ctcgtgaaac cattcgtaag tttattaatg caggctctac aaaggaagtt ctctttacca
    19321 gaggaacgac aaccagcctt aactgggtgg cacgctttgc tgaggaaatt ctcactgagg
    19381 gagaccaggt cttgatttca gtaatggaac accattctaa tatcattcca tggcaggaag
    19441 cttgtcgaaa gactggagca gagcttgtct atgtctatct taaagacggt gccttggata
    19501 tggaggattt gcgagctaaa ttgactgata aggttaaatt tgtttcccta gctcatgcct
    19561 ccaatgttct tggtgtggtc aatccgatca aggaaatcac tcaattagcc caccaagttg
    19621 gggcaatcat ggtagtggat ggtgctcaat ctacacctca tatgaagatt gatgtccagg
    19681 acttggatct ggactttttc gccttttcgg gtcacaagat ggctggtccg actggtatcg
    19741 gtgtccttta cggcaaagaa aagtatcttg agcaaatgtc tccagtagaa tttggcggcg
    19801 agatgattga ttttgtctac gagcaatctg ctagttggaa ggaattgcct tggaaatttg
    19861 aggctggaac gccaaatatg gcaggagcta ttggacttgc gactgcagtt gattatctgg
    19921 aaaagattgg tatggatgcc gttgaagctc atgaacagga attgattgcg tacgtctatc
    19981 caaaactgca ggcaattgag ggattgacca tttacggttc tcaggatttg gctcaacgtt
    20041 cgggtgttat tgcctttaac ctaggtgatc tccatcctca cgatcttgcg acggctctgg
    20101 attatgaagg agtggctgtt cgtgctggtc accattgtgc gcaacccttg cttcagtatt
    20161 tggaagtccc agcaacagct cgtgcaagtt tttatatcta taataccaag gcagattgcg
    20221 acaaactagt cgatgcccta caaaagacaa aggagttttt caatggcact ttctaaacta
    20281 gatagccttt atatggcagt ggtagcagac cattcgaaaa atccacatca ccaagggaag
    20341 ttagaagacg ctgagcaaat cagtctcaac aatccgactt gtggagatgt catcaatctc
    20401 tctgtcaagt ttgatgcaga ggaccgtttg gaagatattg cttttctaaa ttcaggatgc
    20461 acgatttcaa ctgcttctgc tagtatgatg acagatgccg ttttaggaaa aaccaaacaa
    20521 gaaattttag aactggcgac tattttttct gaaatggttc aagggcaaaa agatgagcgt
    20581 caagaccaac ttggagacgc ggcattcttg tcaggtgttg ccaaattccc tcaaagaatc
    20641 aagtgtgcaa ccctagcttg gaatgccctt aagaaaacaa ttgaaaatca agaaaaacag
    20701 taagacaagt ttcttttgtc ttatgaatta ttagaaatga agaaagaaag gatattatgg
    20761 ctgaagaaag agtagaacca aaaccaattg accttggtga atataaattt ggtttccatg
    20821 acgatgtaga gcctgtctta tcgacaggaa aaggactcaa cgaaggtgtt attcgtgaat
    20881 tatctgctgc taagggtgag cctgagtgga tgttggagtt ccgtttgaag tcttatgaaa
    20941 ccttcaaaaa aatgcccatg caaacttggg gagcagactt gtcagagatt gactttgatg
    21001 acttaatcta ctaccaaaaa ccatctgaca aaccagcccg ttcttgggat gatgtacctg
    21061 aaaagattaa agaaaccttt gaacgtatcg ggattccaga agctgaacgt gcttatttag
    21121 caggggcttc tgcccagtac gagtcagaag tggtttacca caacatgaag gaagagttcc
    21181 aaaaattagg tattatcttt acagatacag attccgcact caaggaatac ccagacttat
    21241 ttaatcaata ctttgcgaag ttggtaccgc cgacagataa caagttggca gccctcaact
    21301 cagcagtatg gtcgggtgga acttttatct acgtgccaaa aggtgtcaag gtagatattc
    21361 cacttcaaac ttatttccgt atcaataacg aaaatatagg tcagttcgaa cgtaccttga
    21421 ttatcgttga tgagggagca agcgtccact acgtagaagg atgtacagca ccaacatatt
    21481 caagcaatag cttacacgct gccattgtag aaatttttgc tttggacgga gcttatatgc
    21541 gttatacaac tatccaaaac tggtctgata acgtctataa cttggtaaca aagcgtgcta
    21601 aggctcaaaa ggatgccact gttgagtgga ttgatggaaa cttgggtgcc aaaacgacta
    21661 tgaaatatcc atctgtttac cttgatggag aaggagcgcg tggtaccatg ctctctatcg
    21721 cctttgctaa tgcagggcaa caccaagaca cgggtgctaa gatgattcac aatgctccac
    21781 ataccagctc gtctattgtg tctaaatcca tcgctaaagg tggaggaaag gttgactacc
    21841 gtggacaagt cacctttaac aagaactcta agaaatctgt ttcccacatt gaatgtgata
    21901 ccattatcat ggatgacttg tcagcatcag atactattcc atttaatgaa attcacaact
    21961 cgcaagtggc tttggaacac gaagccaaag tatctaagat ttcagaagag caattgtatt
    22021 atctcatgag ccgtggattg tcagaatctg aggcaactga aatgattgtc atgggatttg
    22081 tagaaccctt tacaaaagaa cttccaatgg aatacgcagt tgagctgaac cgcttgatta
    22141 gctatgaaat ggaagggtca gttggataaa atttgatttt atactcttcg aaaatctctt
    22201 caaaccacgt cagcatcgcc ttaccgtatg tatggttact gacttcgtca gtttcatcta
    22261 caacctcaaa acagtgtttt gagcaacctg aggctagctt cctagtttgt tctttgattt
    22321 tgagtattag atttactcaa aatcaaggat tttgaagatg aacttgtatc aaaaaatcgc
    22381 ggtttaaaat cgcgattttt tataatttct cgttaacaaa gcggacaaac tgattccacc
    22441 aaacttttaa gaagaaggct ttttcaattt tcttgtctgc taccatttcg aaactagggc
    22501 gctctgtggt gatgtaacct tgaccaatca agtccttgtc ttcataagtc aaatggccaa
    22561 ccactgttcc agcttcaagt ggtgctggga ttgctttgga atcaggtgtg aattgaacag
    22621 attgggaaga ttgattccca acacgttcga ttagatagat atcctctgga gccactgcag
    22681 ttactgtatc ttcttttcca tcttgtacag gggctttgct atcttgatag gcatcgcctt
    22741 gttgaacgat tttgcgaagt gtaaatgtag aagaaatata atccattagg gaagatgtag
    22801 ctgtaaatcg agcgtaagga ttattgtctt gatgatctgc atttaaaaca actgtgatga
    22861 ctctcatgcc tttttcgaca gtagtaccaa caaaagactc tccagcctta tctgttgttc
    22921 ctgtttttag cccatcaaaa ccaccacggt aagcaggcat accttctaac atgtagttgg
    22981 ttgaagtgat tgtcatccca gcaaaagtag aagaaggttt tttggtgatt tctaagactt
    23041 gtgggtattt tttgatgagg ttgcgagcaa cgatagcgac atcataagca ctaagcttat
    23101 tttcctcatc ttttttagaa cctgggtaaa tgttatcccc tagagtttca ttgttaagac
    23161 ctgtcgtatt gacaacagtg gcatcctgaa ttccccattc caagagtttt gcccgcatca
    23221 tatcgacgaa atctttttct gagccagcaa ttttctcagc tagggcaata gcggcgctgt
    23281 tggcactaga taccagagtt gcttcaagca actcttcgac agtataatta cgggcctcca
    23341 taggaatatt actggcttca gaatttgtcg tcaattgata aggataatca gaaatatcta
    23401 caggagtgga gagggtaata cttccgtttt ccaaagcttc atagaccaga taaacagtaa
    23461 tcaattttgt tatggaagca atttcgacag gttgcgttgc atccttctca tagagaattt
    23521 taccagtatt tgcctcaaca gcaatcgcat gtttagcggc aatggtaaaa tcttgagcaa
    23581 cagcagtaga agcaccccct aaaagagaga cagttaacaa agttaaaaat atttttttca
    23641 tagtagtctt attctatcat aaagaaaaaa aatattcttg ctttaataat tcatctgtta
    23701 agctttttga aaatatggta aaataaagtg agggaggtaa ctcatgtttc gtagaaataa
    23761 attatttttt tggaccacag aaattttact cttaaccatc atcttttacc tatggagaca
    23821 gatggggtct ttgattaacc cttttgttag cgtgcttaat acaattatga ttccattttt
    23881 attaggaggc tttctttatt atttgacaaa ccctattgtt actttcttaa ataaagtctg
    23941 taaactcaat cgtttgcttg gtattttaat taccttgtgt actttggtct ggggaatggt
    24001 cataggtgtt gtctatctct tacctatttt gattaatcag ttatctagtt tgattatatc
    24061 tagtcaaact atttatagtc gagtacaaga cttaatcata gacttatcta attatcctgc
    24121 gctccagaat ttggatgtag aagctacaat tcagcagtta aacttatcct atgtggatat
    24181 tcttcaaaat atcctaaata gcgtatcaaa tagtgtgggg agcgtcttgt cagctcttat
    24241 cagtactgtt ttgattttga ttatgactcc agtttttttg gtttatttct tattagatgg
    24301 acataaattc ttgcccatgc ttgaaagaac gattctaaag agggatcgct tgcatattgc
    24361 aggcttatta aagaatttaa atgcgacgat tgctcgctat attagtggag tttcgattga
    24421 cgcaatcatt ataggttgtt tggcttatat tggctatagt attattggtt taaaatatgc
    24481 tttagttttt gccatttttt ctggtgtagc caatttaatt ccttatgtgg ggccaagtat
    24541 tggtttgatt cctatgatca tcgcaaatat attcactgat ccccatagac tgctgattgc
    24601 agtgatttat atgcttgttg ttcagcaggt agatggcaat atcttatatc ctcgaatcgt
    24661 aggaagtgtt atgaaggttc atccaatcac gattttagtt ttacttttgt tgtcaagcaa
    24721 tatctatggt gtagttggaa tgattgtcgc agtgccaacc tattctatct tgaaagaaat
    24781 ttctaagttc ttatcccgtt tgtatgaaaa tcataaaata atgaaagaac gagaaagaga
    24841 attagctaag taaaagtcag gagaaccctg atttttcttt actggaagtg gcctttagat
    24901 tagaagactg aaaataagtt aaagtcttaa actaattttc acagctaaga atagtagaag
    24961 ttaatctgat aaaaatcgaa aaaaccagtg gaattctgtg tcagggtaag ttccactggt
    25021 tttcatagtc tattaaagtt cgaatgaaac ctatttatag tagattgaaa ctagaatagt
    25081 acacctctaa ttctaaaaca ttgttagaaa tcgatttgac tgtccttatc tattcgttct
    25141 attcttattt cattttacta tattttggtg caataagtga aaagtagacc gaataatata
    25201 aggattgatt ttatagtttt taaactcaaa tgaattgaaa taaagagagt acgaaaattc
    25261 tcatctgaaa gtattttaga ataattctct tcgtgaattt cttcaaaaca gatagcttca
    25321 tcttaggtat gtgatttctt tttgcatttt tgagttagat aaggtataat ggttttattg
    25381 tcttttgggg tcgttacgga ttcgacaggc attatgaggc atattttgcg actcgtgtgg
    25441 cgacgtaaac gctcagttaa atataactgc aaaaaataac acttcttacg ctctagctgc
    25501 ctaaaaacca gcaggcgtga cccgatttgg attgctcgtg ttcaatgaca ggtcttatta
    25561 ttagcgagat acgattaagc cttgtctagc ggcttgataa gagattgata gactcgcagt
    25621 ttctagactt gagttatgtg tcgaggggct gttaaaataa tacataacct atggttgtag
    25681 acaaatatgt tggcaggtgt ttggacgtgg gttcgactcc caccggctcc attattcctt
    25741 tgcattcttt tgcattcctt ggtaaaacgt tgttaaatca acgtttttta tttttatctt
    25801 tggtattcct ttgcattctt ttgctaaaaa gggagtcaca aacagaccct attttaaaaa
    25861 aaggatagaa aaaaggatac aacatttgtc gcatcctaaa aataatcttt tttcgacgga
    25921 agacatggga ttcgaaccca cgcacgctat tacacgccta ccgcgtttcc aacacggcct
    25981 cttaagcctc ttgagtaatc ttccaatact tactcaaata gtctaccata aaggctctta
    26041 tcttgcaata aaaattctag aaataagaaa aatgatagat tttgaaagaa aatgataaaa
    26101 aat
//
LOCUS       DAVLGK010000033        24892 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLGK010000033 DAVLGK010000000
VERSION     DAVLGK010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24892
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.033"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            117..3218
                     /locus_tag="VXE01_001484"
     CDS             117..3218
                     /locus_tag="VXE01_001484"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV0750369.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASFLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3301..4308
                     /gene="pfkA"
                     /locus_tag="VXE01_001485"
     CDS             3301..4308
                     /gene="pfkA"
                     /locus_tag="VXE01_001485"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV0750370.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4367..5872
                     /gene="pyk"
                     /locus_tag="VXE01_001486"
     CDS             4367..5872
                     /gene="pyk"
                     /locus_tag="VXE01_001486"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV0750371.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTSEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6193..6441)
                     /locus_tag="VXE01_001487"
     CDS             complement(6193..6441)
                     /locus_tag="VXE01_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0750372.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRLNLDK"
     gene            complement(6607..6832)
                     /locus_tag="VXE01_001488"
                     /pseudo
     CDS             complement(6607..6832)
                     /locus_tag="VXE01_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7680..8552
                     /locus_tag="VXE01_001489"
     CDS             7680..8552
                     /locus_tag="VXE01_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV0750373.1"
                     /translation="MKKSRKLATLGICSALFLGLTACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8701..9042)
                     /locus_tag="VXE01_001490"
                     /pseudo
     CDS             complement(8701..9042)
                     /locus_tag="VXE01_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9185..9496
                     /locus_tag="VXE01_001491"
     CDS             9185..9496
                     /locus_tag="VXE01_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750374.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETAEKILALVPQDLIKQI
                     PFFVRKHATTRTIKRILIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9500..10216
                     /locus_tag="VXE01_001492"
     CDS             9500..10216
                     /locus_tag="VXE01_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0750375.1"
                     /translation="MKKYFIGGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10346..11161)
                     /locus_tag="VXE01_001493"
     CDS             complement(10346..11161)
                     /locus_tag="VXE01_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV0750376.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11158..12063)
                     /locus_tag="VXE01_001494"
     CDS             complement(11158..12063)
                     /locus_tag="VXE01_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV0750377.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            12453..12770
                     /locus_tag="VXE01_001495"
     CDS             12453..12770
                     /locus_tag="VXE01_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0750378.1"
                     /translation="MERQTLKDIEVIIVNQSTEEIASISQQMNLSFNIKIIDENSFAE
                     LSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGHFADLVDGVFYFYPWGG
                     IIG"
     gene            12767..13771
                     /locus_tag="VXE01_001496"
     CDS             12767..13771
                     /locus_tag="VXE01_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEV0750379.1"
                     /translation="MTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQF
                     DINNFIWRLYIHSKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLEN
                     YDIERAKKQYIQELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTII
                     SNNCVGGLIYKQLGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWT
                     HEVYPLGHLGDIDIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNK
                     MDNLPYSNKLILVNRPYKNLKSQCVIPGQEHLPELAIMSDPLNTFDIIAWLKKGGNAL
                     "
     gene            13873..16002
                     /locus_tag="VXE01_001497"
     CDS             13873..16002
                     /locus_tag="VXE01_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV0750380.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            15989..16438
                     /locus_tag="VXE01_001498"
     CDS             15989..16438
                     /locus_tag="VXE01_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV0750381.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLINQPED"
     gene            16497..16769
                     /locus_tag="VXE01_001499"
     CDS             16497..16769
                     /locus_tag="VXE01_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0750382.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(17123..17314)
                     /locus_tag="VXE01_001500"
     CDS             complement(17123..17314)
                     /locus_tag="VXE01_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750383.1"
                     /translation="MKHKEHILIGFLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            17742..18500
                     /locus_tag="VXE01_001501"
     CDS             17742..18500
                     /locus_tag="VXE01_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750384.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            18502..20490
                     /locus_tag="VXE01_001502"
     CDS             18502..20490
                     /locus_tag="VXE01_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0750385.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFKKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(20532..21176)
                     /locus_tag="VXE01_001503"
     CDS             complement(20532..21176)
                     /locus_tag="VXE01_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV0750386.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(21148..22197)
                     /locus_tag="VXE01_001504"
     CDS             complement(21148..22197)
                     /locus_tag="VXE01_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0750387.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLNYKSPREDFLMANLNLKFSVRNKSRNRFK
                     FCRSFKYPARRCSWC"
     gene            22904..24379
                     /locus_tag="VXE01_001505"
     CDS             22904..24379
                     /locus_tag="VXE01_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0750388.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSARKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(24345..24863)
                     /locus_tag="VXE01_001506"
     CDS             complement(24345..24863)
                     /locus_tag="VXE01_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0750389.1"
                     /translation="MNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTNKKDAHGIALK
                     LLSDPNREQFQHDNRQVELKILTRHIHRLKKKQSDWKVQYTRCLDIIFPELDKIVGKH
                     SEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASNSRAFCRALKSSPNHQIEIRNSLD
                     KTIDFSYSLSFS"
BASE COUNT         7643 a         4440 c         5212 g         7597 t
ORIGIN      
        1 caaaaataca aatgaataga aaataaatta gtaagctgat gaaatttttc tcaagagaag
       61 ccatttataa gtgaaaatgg tataatatag tgagaaggat agaggagaag tgtaaattga
      121 tcgcacaact agatacaaaa acagtctata gttttatgga aagcgtcatt tcgatcgaaa
      181 agtatgtgag agcagctaaa gaatacggct acactcattt ggctatgatg gatattgaca
      241 atctttatgg cgctttcgac tttctagaga ttacaaaaaa atacggcatt catcctttgc
      301 tagggcttga aatgacagtg tttgtagatg atcaggaagt gaatttgcgc tttttagctc
      361 tatctagtgt gggctatcag cagttgatga agctttcgac agccaagatg cagggggaga
      421 aaacttggtc agtcctgtcc cagtacctgg aggatatcgc ggtcattgtg ccttattttg
      481 atagagttga gtcgttagaa ctaggctgtg attactatat aggggtttat ccagaaacac
      541 tagcaagcga atttcatcat cctatcttac ctctttatcg ggtcaacgct tttgaaagca
      601 gggatagaga agttcttcaa gttttaacag cgattaaaga aaatctaccg ctcagagaag
      661 ttcccttgcg ttcgagacaa gatgtcttta tatcagcaag ttttttagag aaactattcc
      721 aagagcgttt tccgcaagct ttggacaatt tagaaaagct tatttcaggc atttcttacg
      781 acttggatac tagtctgaaa ctgcctcgtt ttaatccagc tagaccagca gtagaggagt
      841 tgagagagcg tgctgaactg gggcttgttc agaaggggtt gactagtaaa gaatatcaag
      901 atagactaga ccaagaattg tctgttattc atgatatggg ctttgatgat tatttcttgg
      961 ttgtttggga tttgttgcgt tttggacgat cgaatggcta ttatatggga atgggaaggg
     1021 gttctgcagt aggcagtttg gtttcttatg ccttagacat cacggggatt gacccagtag
     1081 agaaaaatct gatttttgaa cgctttctta atcgtgaacg ctataccatg cctgatattg
     1141 atattgatat cccagatatt tatcgtccag attttatcag atatgttggt aataaatatg
     1201 gtagtaaaca tgcggcacaa atcgttactt tttcaacctt tggagccaag caagctcttc
     1261 gagatgtctt gaaacgcttt ggtgtgccag agtatgaatt atctgcaatt actaagaaaa
     1321 tcagttttcg tgacaatctt aagtcggcct atgagggcaa tctccagttt cgtcagcaaa
     1381 tcaatagtaa gttagaatac caaaaagctt ttgagattgc ttgcaagata gagggctatc
     1441 caaggcaaac ctctgtccat gcggctggtg ttgtaattag tgaccaagat ttaaccaact
     1501 acattcctct aaagtatggt gatgaaattc cactgactca gtatgatgct catggagttg
     1561 aggctagcgg acttttgaag atggactttc tgggactacg aaatttgacc tttgtccaga
     1621 agatgcaaga gttgcttgct gaaatagaag gtattcacct taaaattgaa gaaatagatt
     1681 tggaagacaa agaaacgtta gctttatttg cctctggaaa tacaaaaggt atctttcaat
     1741 ttgagcaacc aggtgccatt cgtctgctta agcgtgtgca accagtctgt tttgaagatg
     1801 tcgtcgcgac tacttctcta aatcgaccgg gtgctagtga ctatatcaat aattttgtgg
     1861 caagaaagca tgggcaggaa gaagtgactg ttctggatcc agtactggag gatattttgg
     1921 ctccaaccta cggcataatg ctctatcagg agcaggttat gcaggttgcc cagcgatttg
     1981 ccggatttag tcttgggaaa gccgatattt tgcgtcgggc tatggggaaa aaggatgcct
     2041 ctgccatgca tgagatgagg gcttccttta ttcaaggttc attagaagct ggtcatactg
     2101 tggaaaaagc agagcaggtc tttgatgtta tggagaagtt tgcaggttat ggttttaaca
     2161 ggtcacacgc ctatgcctac tcagccttgg ccttccagtt ggcttatttt aaaacacatt
     2221 atccagccat tttttatcag gtcatgttaa attcttccaa cagtgattac ttaatagatg
     2281 cacttgaagc aggttttgaa gtagcctctc tatccatcaa cacgattccc tatcacgata
     2341 aaattgccaa caaggccatc tatctaggtt tgaaatccat taaaggagtc agtaatgatt
     2401 tagctctctg gattattgaa aatagacctt attctaacat tgaagatttt atagctaaat
     2461 tacctgagaa ttatctgaaa cttcctctgc tagaaccttt ggtaaaagtt ggtcttttcg
     2521 attcatttga aaaaaatcgt caaaaagtat ttaataattt agctaatcta tttgaatttg
     2581 tgaaagagtt gggaagtttg tttggagatg ctatttatag ttggcaggaa tcggaagatt
     2641 ggacggaaca agaaaaattt tatatggaac aagagctttt agggataggt gtcagcaaac
     2701 atccactaca agctattgca agtaaggcta tttacccgat taccccaatc ggaaatttgt
     2761 cagaaaatag ctatgctatt atcttggttg aagttcagaa aataaaagtg attcgtacca
     2821 aaaagggtga aaatatggcc ttcttacagg cagatgatag taagaaaaaa ttggatgtca
     2881 ctctcttttc agacttatat cgtcaggttg gacaggaaat aaaagaggga gccttctact
     2941 atgtaaaagg aaaaatacaa tcacgtgatg gccgtctgca aatgattgca caagaaataa
     3001 gagaagcagt tgctgaacgc ttttggatac aggtgaaaaa tcatgaatcg gatcaagaaa
     3061 tttcacgcat tttagaacaa tttaaaggcc caatcccagt catcatccgg tatgaagagg
     3121 aacagaaaac catcgtttct ccccatcatt ttgtagctaa atccaatgaa ttagaggaga
     3181 aattgaatga aatcgttatg aaaacgattt atcgctaaaa atacggaaaa tagaagaatt
     3241 ttaaaatcaa atgtgatata atcaagaaga atgttaaaag aaaaaggagc ataaaccaat
     3301 atgaaacgta ttgctgtttt gactagtggc ggagacgcac ctggtatgaa cgctgccatc
     3361 cgtgcagttg ttcgtcaagc aatttcagaa ggaatggaag tgtttggtat ctatgacgga
     3421 tatgctggta tggttgctgg tgaaattcat cccctggatg cagcttcagt aggggacatc
     3481 atttctcgtg gtggtacttt tcttcactca gctcgttatc cagagttcgc tcaacttgaa
     3541 gggcaactta aagggattga gcaattgaaa aaacacggaa ttgaaggtgt agttgttatc
     3601 ggtggtgacg gatcttacca cggcgctatg cgtttgactg aacatggctt cccagctatt
     3661 ggtcttccag gtacaatcga taacgatatc gttggtactg actttacaat cggttttgac
     3721 acagcggtta ctactgccat ggacgctatc gataagattc gtgatacatc atcaagtcac
     3781 cgtcgtactt ttgtaatcga agttatggga cgtaacgctg gtgatatcgc tctttgggct
     3841 ggtattgcaa ctggtgctga tgaaatcatc atccctgaag caggcttcaa gatggaagat
     3901 atcgtagcaa gcatcaaagc tggttatgaa tgtggtaaaa aacacaatat catcgtctta
     3961 gctgaaggtg tgatgtcagc ggctgaattt ggtcaaaaac ttaaagaagc tggagataca
     4021 agcgaccttc gtgtaacaga acttggacat attcaacgtg gtggttctcc aactgcgcgt
     4081 gaccgtgttt tggcgtcacg tatgggtgca catgctgtta aacttcttaa agaaggtatc
     4141 ggtggtgttg cggttggtat tcgtaacgaa aaaatggttg aaaatccaat tcttggtact
     4201 gcagaagaag gggcattgtt tagccttact gcagaaggta agattgtggt taacaacccg
     4261 cacaaagccg atattgagct atctagcttg aataagagct tgtcataatt tacaatttag
     4321 ttaataagac caaaaaggtc atatatataa aggagtcaca aaaatcatga acaaacgtgt
     4381 aaagatcgtt gcaactttgg gtcctgcggt agaaatccgt ggtggtaaaa aattcggtga
     4441 ggatggatac tggggtgaaa aacttgatgt tgaagcttca gctaaaaaca ttgctaaatt
     4501 gattgaagct ggtgctaaca cattccgatt caacttctca cacggcgacc accaagaaca
     4561 aggtgagcgt atggcaactg ttaaacttgc ggaaaaaatt gcaggtaaaa aagttggttt
     4621 ccttcttgat acaaaaggac ctgaaatccg tacagaattg ttcgaaggtg aagctaaaga
     4681 atattcatac aaaactagtg aaaaaattcg tgttgcaact aaacaaggaa tcaaatcaac
     4741 tcgtgaagtg attgcgttga acgttgctgg tgctcttgat atctatgatg atgttgaagt
     4801 tggtcgtcaa gttttggttg acgatggtaa acttggtctt cgtgtggttg ctaaagatga
     4861 tgcaactcgt gaatttgaag ttgaagttga aaacgatggt atcatcgcta aacaaaaagg
     4921 tgtgaacatc cctaacacta aaattccttt cccagctctt gctgaacgcg ataacgacga
     4981 tatccgtttc ggtcttgaac aaggtatcaa cttcatcgca atttcattcg tacgtactgc
     5041 aaaagatgtg aacgaagttc gtgcaatctg tgaagaaact ggaaacggac atgttcaatt
     5101 gttcgctaaa atcgaaaacc aacaaggtat cgataactta gacgaaatca tcgaagcagc
     5161 tgatggtatt atgattgctc gtggtgatat gggtatcgaa gtaccgttcg aaatggttcc
     5221 agtttatcaa aaaatgatta tcaagaaagt caatgctgca ggtaaagttg ttatcactgc
     5281 aacaaacatg cttgaaacaa tgactgaaaa accacgtgca actcgttcag aagtatcaga
     5341 cgtattcaac gctgttatcg acggaactga cgctacaatg ctgtcaggcg agtctgcaaa
     5401 cggtaaatac ccactcgagt cagtaactac aatggctaca atcgacaaga acgctcaagc
     5461 tcttcttaat gaatacggac gtcttgattc agattcattt gagcgtaact ctaagacaga
     5521 agtaatggct tctgctgtta aagatgctac tagctcaatg gatatcaaat tggttgtaac
     5581 tcttactaag acaggtcata ctgcacgttt gatttctaaa taccgtccaa atgctgacat
     5641 cttagcattg acatttgacg aattgacaga acgtggcttg atgttgaact ggggtgttat
     5701 cccaatgttg acagatgctc catcttcaac tgacgatatg ttcgaaatcg ctgaacgtaa
     5761 agcggtagaa gcaggtctcg ttgagtcagg cgatgatatc gttatcgttg ctggtgtgcc
     5821 agtaggagaa gctgttcgca caaacacaat gcgtatccgc acagtacgtt aagaaaaata
     5881 taaaaaccta tcatatccag ctttctagcc tgtatgatgg gctctttttt tgtccagggg
     5941 gcaaaaaggg ggcaaaactt tcataatgga ttgatactct tcgaaaatca aattcaaacc
     6001 acgtcagcgt cgccttaccg tatatatgtt actgacttcg tcagttctat ctacaacctc
     6061 aaagcagtgc tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga
     6121 gtatgaaata agatatgcac aaattgatta gaaagtcaaa tgaatttcta caaatgtttt
     6181 agcaatcgca atctacttgt ctagattcaa tctgatatat tttcgattta atgatatggt
     6241 atttaaaacc tccaaagtag cttgctccat tcttttactt acgtgagtgt agatgttatt
     6301 tactgtttta gcgtttttgt gttccactct aaccattata gcattcttct cagctagtgt
     6361 actaaggagt gtgtgcctga aaatatggga actaaggggc tggtttatcg gtttctctag
     6421 tttagtattt gccttttgca aagtgatctt aaatgccttt ctctaaattt acatatcact
     6481 attgtttaac aaaatctaat ctactttagg tcacttattc tttttttgaa atgtagaatg
     6541 aactttttca aagtttttcg aatcttttaa aatctgtttg ttttatatcg ccattctccc
     6601 ccttttttaa ttctccctat atagcctgat agctttcccg atggtacgaa tatggttgct
     6661 ttcgtctagg tggatgtcgg ggtattcggg attgagtttt tttgaggcag ccttggcgga
     6721 gtttcttgac atagttagtg ccgtctactt ggaagatgcc gatggtatta tagtcaatct
     6781 gtggggtatt cttgataaat aggtagtcgc tgtttcttat ctttggcttc atggacttgc
     6841 tgacgacata agcgattggg tcgtagtcgt ctgggataat ggaaactcca taactaaatc
     6901 gtcgtcctgc atcgagcggc tacctgcaga gataaactac ctaacacgag agtaagtagt
     6961 ctgtctgtag tcgtccagtc tgatgatttt tacgatactt cgtttttctg atcatacagt
     7021 tgcctctcgg cataggtcag aactttacct tgtctgggtg gtgcccgttg gtcgtagata
     7081 gattggatat cgctaggaga atccttttga actggaggaa agagggcatc aatcaagcta
     7141 ctgaatactt taactaagtc aaatatagta tttttcttag tagacctaac ccttttttca
     7201 taatttctaa tggtgttttt acttatacct atcttagtac ccaattctta ttgagtccaa
     7261 ccattactag tctatattgt tttatagttg attgagtttg gaatagtacg ctgtagctgc
     7321 taaaacattt ctaggaatta atttgccttt cctaatagag ttgttcatat cttatttcaa
     7381 tctactatat ttttcacctc taacaatcgc aatctcttct ttatccatga ataaaaacga
     7441 tttctatttt tgtaagtaaa gcatcacacg aaatccacga aaatgaaaac ctttgttgtg
     7501 ttttcgtaaa aaatttgttg acagagcacg aaacgcctac tataattaaa tcaagtttaa
     7561 ggaaataaca aaaaaacaaa tcggagggaa agacgatgaa cacattaaat gagaaagtaa
     7621 tcaatatctg taaagcagta gttaaagaaa ctttaatcca agacatttag gagaaagaaa
     7681 tgaagaaatc aagaaaatta gccacattag gaatctgttc agctttgttt ttaggcttga
     7741 ctgcttgtca acaacaacat gctacttctg aggggacgaa tcaaaggcaa agcagttcag
     7801 cgaaagttcc atggaaagct tcatacacca acctaaacaa ccaggtaagt acagaagagg
     7861 tcaaatctct cttatcagct cacttggatc caaatagtgt tgatgcattt tttaatctcg
     7921 ttaatgacta taataccatt gtcggctcaa ctggcttatc aggagatttc acttccttta
     7981 ctcacaccga atacgatgtt gagaaaatca gtcatctctg gaatcaaaag aagggcgatt
     8041 tcgttgggac caactgccgt atcaatagtt attgtctttt gaaaaattca gtcaccattc
     8101 caaagcttga aaagaatgac cagttgcttt tcctagataa tgatgcgatt gataaaggaa
     8161 aggtctttga ttcacaagat aaggaagagt ttgatattct attttcgaga gttccaactg
     8221 aggcaactac agatgtcaag gttcacgctg aaaagatgga aacattcttc tcacaatttc
     8281 aattcaatga aaaagctcga atgctgtctg tagtcttgca cgacaatctg gatggcgagt
     8341 atctgtttgt aggccacgtt ggggtcttag tacctgctga tgacggtttc ttatttgtag
     8401 agaaattgac tttcgaagag ccctaccaag cgattaaatt tgctagtaag gaagattgct
     8461 acaagtattt gggcaccaag tatgcggatt atacaggcga gggactggct aagcctttta
     8521 tcatggataa tgataagtgg gttaaacttt aatagtgtta tgatatgaca gtaatcttag
     8581 gatttttatt tctatttttg atgagttggt gggttatttc aatcgttaat agccagaaac
     8641 cacgcaaaaa tgaaacattt attggctatg tccaaagata cgatattgat gggaatggct
     8701 atcaatcatt accgtgtcct cagagctgag aggagttctt gaaatcgtaa caccactttg
     8761 aacaagagtt acttcaaccc attggctccg acggattaag ttgctttcgt gaataccaaa
     8821 atcagccgca atttgttcat aagtgcggta ttctcgcaca tattgaagag tggctataag
     8881 aaggtcttct aggcttaatt taggttttcg tccacctttt gcatgtttaa gttgataagc
     8941 tgtttttaat acagctaaca tctcttcaaa agtcgtgcgc tgaacaccaa caagacattt
     9001 caatcgtgca tcagttagtt gtttacttgc ttcatcattc atagaactat tataccatgt
     9061 tttgtttcgc aggaaatcta atgctaaaat cttatcagtg agaagatttc ttaaagttta
     9121 ttctttgtag tttcatctgt attagtacat aatttaacct agagaaaata ggaggactaa
     9181 tcgaatggaa ttaaaagatt ttacagaaaa agaacaggaa atgattaaga aaaggcttac
     9241 aatgtctaat attagtgaca aagaaactgc tgagaagatt ctggcgctag taccacaaga
     9301 cttgattaag caaatcccgt tttttgtcag aaaacatgct acaacacgta cgattaaacg
     9361 cattttaatt gaataccctg aactctacgc tgtagctcaa acaagtggtg agattccaga
     9421 aaaagaacgc gaagaattgc gtcagattat cacaactatc tttgaacaaa agatgaataa
     9481 gcatagtatt aagtagagaa tgaaaaaata ttttattggc ggtttgggaa gcaatgccta
     9541 tcatagcaag gatttttttc aagaactaga ttcgcaggtc tattttctaa atccatatga
     9601 aaagcatctt cgagatgaaa cagaattgaa atcatggttt aaaaatgaga ttgtagagga
     9661 agaatctatc tgtctgatag gccattctct tggaggagat ttagctcgtt atttcgcatc
     9721 ggaatttgaa gaagtaaaga aactgattct tttggatggt ggctatctag atttagataa
     9781 gattttacct ttggatacag agttagagga aactaaaaat tatatcaaat ctcaaattgt
     9841 ttcggactta gctcttctta tttctaaaga gaagtccgaa gcaaagcatt ggtcagaaaa
     9901 tatggagaaa gctgtaagac agtcctatca ctggaatgtt gagtataata gatatgagtt
     9961 ggctataaat tatgaaaata tagaagcgat actccgccta cggagaaaaa tacaagcttt
    10021 taagagagaa gtgggagata ccttgtttat tagtcctcgc tatcctaatg gagctacatg
    10081 gagagaggaa gccctaaaag aattgccaga ctattttaat actatttttt tagaaaactt
    10141 tggccatgag ctttatactc aagcacctaa agaaatcgct agtctaatga atgagtggct
    10201 cgcttatttt ctatgagcta cttgtattgc tggaaatggt ataagatgaa aatctacaag
    10261 tcactaattt tcatataaca aaaaaacgaa caggctcttt ttctgttatt cagaagagaa
    10321 cttgttcgtt tttatcttga ttttcttaaa aagctctata tacataggga ttttctggtt
    10381 tatcgacttt ggtaaagctg tcgatttcca aggttggaag gttttgtttg agttctttat
    10441 ggtagtgatt gaccagtttt cctttggctg taatccaggt gttgttttca tactgccggg
    10501 tattgccctt ggtcagcaat ccatagacac cagaatctgc gatacagtgg ataatgccga
    10561 atcggaacag aaattgacta ttggcatgac tggggtcgtt atagacaaag cctgtaaact
    10621 ggattgtctt gccctcaaat tcatctggat agtcgtagat agcctccatg acttccatat
    10681 agttttcatt agtgatctga atactatctt gggataagta tttatccgcc gccgttcgca
    10741 tttccttttc ataggctgat tttgaaaaat aagaactagt atctggtttc aaatattggc
    10801 ttgtagtccc ttcacttgtc tgaatagcta gatccgttcc ttccgatagg gggaaatgat
    10861 aacctttagc agaaacggtc tgagaatcca agctaacagt tgggaaagtt aagccgatga
    10921 caagtggaat agccagaaga gaaatactcg tcatcttggc caatcggctg ttcagatgac
    10981 tgtgggtttt gacttgcttc atccagatat acaattgaac aattgccaag ataaaggaaa
    11041 gcaccatgga gatataggcc agataggaat agtgcatgtt gatgtactgg tttagtttgc
    11101 ccgacagatg gaggtaaata gtcagttcaa aatagccagc taaaactaaa aatcgaatca
    11161 taggatgact ccaatcaaga gagaataggc taaaacgacc agagtcacaa tcgtaatgaa
    11221 gtgactaata aatcgtgctt tcaagtaatt tttcatcatg agaatatttt tgatatccag
    11281 cattgggcca atgacgagaa aggccagaac tggtgccaaa ccgaaactcg agagtagaga
    11341 agcacctata aaggcatccg cctcactaca gagcgaaaga agaaaggcta aaagcatcaa
    11401 gagcaggata gcaaaaagag gagtcgcact gatagaggtc agaatccgag tcggaacgta
    11461 gacctgtatt atagaagcaa agaggcagcc aaataccaaa taacgccccg tatcaaaaaa
    11521 ttcatcaatg gcctgcacaa agacttgaaa aacttttttt gcagaactca agtaagaaaa
    11581 atcatgctca tgacaagcca gacgattttc tttctgaatc ggttcttgcc agaaaaatcc
    11641 tagaaaaatt cctagtatta cagccacaag aatggaaccc agagctcgta atagggcgac
    11701 atggaaggag ttgccaaagg cagaataggt cgcaaaaaga acaatgggat tgataacagg
    11761 tgctgtcaca agaaaaggaa cggccgtgta acttggaacc tttttttcca gaaaacgatt
    11821 gatgatgggg acgattccac attcacagga agggaaaagt ataccgacaa aggtcccaaa
    11881 aaagattctc ccccaacgat ttcgagggag aaaatgataa accttgtcag gtgtgatata
    11941 aacttcaatc agccctgaga caatgcttcc tatcagaacg aagggaaggg cttcaatgat
    12001 aatggagaga aaaatggctc cagtttgaag tacactagat gggagttgtt gaaaagcagt
    12061 catctagttt ttcttttctg ctttggcttt tttctctttg tcatcaggga aagtgacttg
    12121 tttcaaatca gggagtttag caaactcttc aaacatcttg tccaagtcgt ctcgttttgt
    12181 aaatttgaca gccataggtg tacctcgatt ctaaattcta cctctattat actattattt
    12241 tgcggaaaag ggaaaagtta aaatttcaaa ttgagtagct aagagataat atagcttgat
    12301 attacctgat atatatcata attgtgctat aattaaataa aaagaaaatc attatcagaa
    12361 aattatggga ggtagtcaaa ctgacttact caattagtgt tgttttgtta catcaaggag
    12421 ataaaaatag tttattagag tctttgtcaa tagtggagag acaaacatta aaagatatag
    12481 aagttattat tgtaaatcaa tctacagagg agatagcttc cattagccaa cagatgaatc
    12541 tatcatttaa tattaagatt atagatgaga attcttttgc tgagttgtct gatatgatta
    12601 caggagatta tattacgttt ctatcttcaa atgattcatt atttgattgg acatttgaaa
    12661 agatgtatca tgcgataaaa ttatccgatt ctgatgttgt tcttggtcat tttgctgatt
    12721 tggttgatgg agtattttac ttttatcctt ggggggggat aattggttga cagaaaattt
    12781 aacgaatgtt caagttttac aaaagatgga tgatacagat catcgaatta gaaaacaata
    12841 tcgctcatta tttggaaaat tattcaatag taagctttta cgaaaaataa atcaatttga
    12901 tataaacaac tttatttgga gactttatat tcactctaaa actgcaacct atattaattt
    12961 cccgacatat atctataaac ctgttataga tgctaaacct ctaaaagact cctacaaaat
    13021 catattagaa aattatgaaa atagaatcaa agattgcgcc gtcttagaaa actatgatat
    13081 agaaagagcg aaaaaacaat atattcaaga attggcaaat tttagtgctt ggttaaaaaa
    13141 tgacggtgaa tatttagatt ctgatattgt ttatcataag ttaatagctg cagagaaagg
    13201 aattttccct tttcttgagc ttgatagatt agattttacg attataagta ataattgtgt
    13261 tggaggatta atttataaac agcttggttt tcaatataga acaccttttg ttggtttatt
    13321 tattcttcct gatgattatt ataaacttac aaagcatttt cgttattata tggaacaaga
    13381 acttgttttc gaagaggaac ttatttcacc gagctggact catgaagttt atcctttggg
    13441 gcacttagga gatatagata ttcattttct acattattct agtattgaag aagcacgaac
    13501 taagtgggaa aaaagaaaaa aacgcataaa ttggaataat ctttatttta aatttgataa
    13561 taaagattca gctagtgaag aaattttaaa taagatggat aatcttcctt attctaataa
    13621 attaatttta gtcaatcgtc catataaaaa tttgaaaagt caatgtgtta ttccaggtca
    13681 ggaacatctt ccagaactgg ctattatgtc tgatccatta aatacttttg atatcatagc
    13741 ttggttaaaa aaaggtggca atgctcttta agtgcaagtt attgcgctgt agcatataaa
    13801 tctatttcct acatattttt taaatgttct acgagttaat ttgaaacgtt tagcttgtgg
    13861 tataatagat ttatggataa aaaatatgaa aaaatctctc aggatttggg agtgacgtta
    13921 aagcaaattg ataccgttct aagtttgaca gctgaagggg cgactattcc ctttatcgcg
    13981 cgttatcgca aggacatgac tggtagtctg gatgaggtgg cgattaaggc tattattgat
    14041 ttggataaaa gtctgacaaa tctcaatgac cgtaaggaag ctgtcttagc taagattcaa
    14101 gaacaaggta agttgaccaa ggaattggaa gaagctatct tagttgccga aaaattagca
    14161 gacgttgaag aactctatct tccttataag gaaaagcgtc gtaccaaggc aaccattgcc
    14221 cgtgaagctg gactctttcc tcttgctcgc ttgattttgc agaatatagt tgacttagag
    14281 aaagaagctg aaaagttcgt ctgtgaagga tttgcgactg gcaaggaagc cttgaccggt
    14341 gcagttgata ttttggtcga agccttatcg gaagatgtga ccttgcgttc tatgacttat
    14401 caggaagtgc tgagacactc taaactcact tctcaagcca aggatgaaag tcttgatgaa
    14461 aagcaggttt ttcagattta ttatgatttt tcagagacag ttggaactat gcaaggctat
    14521 cgtaccttgg ctctcaatcg tggggagaaa cttggtgtct tgaagatcgg ttttgaacat
    14581 gcgacggacc gtattcttgc cttctttgct actcgtttca aggtgaaaaa tgcttatatt
    14641 gatgaagttg ttcagcaatc cgttaagaaa aaggtcttgc ctgctattga gcgtcgtatt
    14701 cggacagaat taactgagaa agctgaagag ggagctatcc aacttttttc tgacaatctg
    14761 cgcaatctcc tcttggttgc tccactgaaa gggcgcgtgg ttcttgggtt tgacccagcc
    14821 tttcgtacag gtgccaagct agctgtcgtg gatgcaacag gaaaaatgct gacaactcag
    14881 gttatttatc ctgttaaacc agcatcagct cgtcaaatcg aagaagccaa gaaagattta
    14941 gcagatttaa ttggtcaata cggtgtagag attattgcca ttggaaatgg aacggccagt
    15001 cgtgaaagcg aagcttttgt agcggaagtt ctgaaagatt tccctgaagt cagctatgtt
    15061 atcgttaatg aaagtggtgc ttctgtctat tctgccagcg aacttgctcg tcaggagttt
    15121 ccagacttga ccgttgaaaa acgctctgcc atttctatcg cccgtcgttt gcaagatcct
    15181 cttgcggaat tggtcaaaat cgatcctaag tcaattggtg tcggtcaata ccaacacgat
    15241 gtcagtcaga agaaactatc tgagagtctg gactttgtcg tggatacggt ggttaaccaa
    15301 gtcggtgtca atgttaatac agctagccca gctcttcttt ctcacgtggc tggactcaat
    15361 aaaacaattt ctgaaaatat cgtcaaatac cgtgaggaag agggaaaaat cacttcacgc
    15421 tcccaaatca agaaagttcc tcgtttgggg gccaaggctt ttgaacaggc tgctggtttc
    15481 ctccgtatcc ctgaaagtag caatatcctt gataatacag gagttcaccc agaaaattac
    15541 gctgccgtta aggaactctt caaatgcttg gacattaagg atctgaatga agaggcccaa
    15601 agtaaactca agtcgctttc agtcaaggaa atggcgcaag agttagacct tggtccagaa
    15661 actcttaaag atatcattgc agatcttctc aaaccaggtc gagatttccg tgattccttt
    15721 gatgctccag ttctccgtca agatgtccta gatatcaagg acttagtggt tggacaaaag
    15781 ctagaaggag tggtgcgtaa cgttgttgat ttcggtgctt ttgttgatat cggaattcat
    15841 gaggacggtc tcatccatat ttcccatatg agtcgcaagt ttatcaaaca ccctagtcaa
    15901 gtggtggcag ttggagattt ggtgagcgtt tgggttaaga aaattgatac tgaacgtgaa
    15961 aaagttaatc tgtctctcct agctccaaat gaaactgact gattacgtca agcaggtttc
    16021 actagaagac ttcggcagac cttttatcca tcatgtccag tggaataggc gtctacgttc
    16081 gacaggtggg cgatttttcc ccaaagatgg gcatttggat tttaatccca aggtttatca
    16141 ggaactgggg ttggacgttt ttaggaaaat tgtccgacat gaactctgtc attatcacct
    16201 ctattttcaa gggaaaggct atcaacacaa ggatcgggat tttaaggaac tgttgaaagc
    16261 agtagatgga ttacggtttg taccatcctt gcccaatagt aactccaagc caatcaagct
    16321 ctatcgttgc caatcctgcc agcaaactta tcagcgtaag cgtaggattg atacccaacg
    16381 ctatcgctgt ggactttgtc gaggtaaatt gctactaata aatcaacctg aggactgatg
    16441 aaagccgagc ctacccgtga tatactatgt ctaacctagc agaaagagga aatatcatga
    16501 acagtaaatt ttataaaatg agacgaaatc gcatgatttc aggagttttg gcaggtctgt
    16561 cagacaagtg gaactttgat gttacccttg tacgttttct gtttgccatt tttacagtcg
    16621 caaactttgg acttggggtg attatctata tcatcctagc ttctatcatg ccaaccaagg
    16681 aagaaatcga agcagaaatg tacggaacag gcccacgtaa acgcaaagaa gctcaagcca
    16741 ttgacgataa tgaaggctgg ttttggtgag gttttacaaa agatttggaa tacgcaaaaa
    16801 gctttaaatc aatagtctaa actgcttgat ttaaagcttt tttactttta tactcaataa
    16861 aaatcaaagt gcaaactagg aagccagccg caggctgtaa tttagtcggc aatgtgaagt
    16921 tgatatagtt tgcactttga tttttgaata gtattaataa tatttcgcca gcttcatcta
    16981 caaactatag tggattggaa ctagaatagt acacctctac ttctaaaaca ttgttagaaa
    17041 tcgatttgac tgtcctgatc gatttgtcct gttcttattt cattttacta taaaagcagt
    17101 aatttaaatg cagtttttta atctattttt gctgctgaga caatacattt ttggaaaaat
    17161 ggtggatgct gataacaact gataaccagc aaataacata agcagtgccg gtaaattctg
    17221 taccgataaa gtgtgtgtgt tcaactaaga gctgaccgat gaatggagag agcagataga
    17281 gaaatccgat gagtatatgt tctttatgtt tcattaaagc gcaccttctt tccttatagg
    17341 tagttcgatt tgaaagtgtt caatttaatg gtgtgtcatc taggtaacct tactaaaatg
    17401 ttagttcccg cttcctcctt ttcaaagtaa gccttttcgc acttatattt tacaacttta
    17461 aaaataggaa atcaaatcat tttctaagta attttgctta tatttccccc aatcttacaa
    17521 aaatgtaaga ttaaagtctc ttttgtaagg ttaggttatg gcaagcggtc tttttttgat
    17581 gtaaactaga ctcataaaga acaaaggagt aacatcatga aacaaatcgt acataagaaa
    17641 actagaaaac caagtcacaa agaaattgag cgcgttcagc tgggatgcac tatgatgcaa
    17701 gctacatttc attttatggg atattaagaa aggagattct catgacactt ttagatgtaa
    17761 aacacgttca aaaaatttat aaaacacgtt ttcagggcaa ccaagtagaa gccctcaagg
    17821 atattcactt taccgtagaa aagggtgact atgttgccat catgggtgag tctggttctg
    17881 gtaaatccac tcttctcaat atcctagcta tgctggacaa accaagtcgt ggtcaggttt
    17941 acttaaatgg aactgataca gcaactatta aaaattcaca ggcttctagt ttccggcgtg
    18001 aaaagttggg ctttgtcttc caagacttta acttgctaga tactctatct gtaaaggaca
    18061 atatcttgct tccgcttgtc ttgtcaagaa gacctattac agagatgatg aagaaattgg
    18121 tggtgacagc tgagaatctg ggaataaacc aattacaaga gaagtaccct tacgagattt
    18181 ctggtggcca gaaacagcgt gtagcagtag cacgcgccat catcactgaa cctgaaattc
    18241 tccttgcgga cgaaccgaca ggagctcttg actccaagtc atctgcagcc ttacttgatg
    18301 tatttgatga aatcaatgag cgcggccaaa ccattctcat ggtaacccac tcaacagcag
    18361 cagctagcag agctaaacgt gtactcttta tcaaagacgg cattctttac aatcaaatct
    18421 accgtggaga gaagacagaa cgtcagatgt tccaagaaat ctctgatacc ttgactgtca
    18481 tggcaagcga ggtgaattag tatgtttcga ttaaccaata agttagcggt atcgaacttg
    18541 attaaaaacc gcaaactcta ctatcctttt gcgctggctg ttctcttggc agtcactgtc
    18601 acctatctct tttattctct aaccttcaat cctaagattg cggaaatccg tggaggaaca
    18661 accattcagg ctacacttgg atttggtatg tttgtcgtca cccttgcgtc agccattatc
    18721 gttctctatg ccaatagttt tgtcatgaag aaccgttcca aggaactagg aatttatggc
    18781 atgttgggct tggagaagcg tcatcttatc agtatgacct ttaaggagtt agtggtattt
    18841 gggattctaa ctgttggagc gggtatcggt attggagcct tgtttgacaa gttaattttc
    18901 gctttcctgc tcaaactaat gaaattgaag gttgagctgg ttgctacctt ccagacgaaa
    18961 gttgtcatta cagtgcttgt tgtcttcggt ttgattttcc taggcctcat gttcctgaat
    19021 gcccttcgaa tcgcccgtat gaatgccctc cagctctctc gtgagaaagc tagtggagag
    19081 aaaaaaggtc gcttccttcc tctccaaacc attcttggtt ccataagttt aggaattggc
    19141 tattatcttg cccttacggt aaaagatcct cttacagcct taacaacctt cttcatagct
    19201 gttttactgg ttatctttgg gacttatctc ttgtttaatg cagggattac cgttttcctc
    19261 caaatcttaa agaaaaataa gaaatactat taccaaccaa ataatctcat atctgtttct
    19321 aacttgattt tccgtatgaa gaaaaatgca gttggactag ccaccatcgc tatcttgtca
    19381 acaatggttt tggtaaccat gtcagcagcg acaagcattt tcaattcctc agaaagcttt
    19441 aaaaaagttc taaatcctca tgattttggg gtttcagggc aaaatgttga aaaagaagat
    19501 ttggacaaac tcttgagcca gtttgcaagt gacaaaggtt ataagattaa agagaaagaa
    19561 gtgcttcgtt acacttactt tgctgttgcg aatcaagaag gaaccaagtt aactattttt
    19621 aaaaaaggac aaaaccgtgt ccaaccaaaa acagttttca tggtatttga ccaaaaagat
    19681 tatgaaaata tgactggtca aaaactgtct ctatcaggaa atgaggtcgg tctctttgcc
    19741 aaaaatgacg gactgaaagg acagaaagct ctaactctaa atgatcatca attttctgtc
    19801 aaagaagaat ttaataaaga tttcattgtc aaccatgttc caaataagtt taatatcttg
    19861 actactgatt acaattacct tgttgttcct gatttacaag cctttttgga tcaattccca
    19921 gattcggcta tctataatca gttttacggt ggtatgaatg tagatgccag cgaagaagaa
    19981 caactcaagg tcgctgagga gtatgaaaac tacctcaatc aatttaatgc tcaattagac
    20041 acagaaggta gctatgttta tggtagcaat ctagcagatg ctagttctca gatgagtgcc
    20101 ctctttggtg gtgtcttctt tatcggtatt ttcctatcca ttatctttat ggtcggaact
    20161 gttctggtca tctactacaa acaaatttct gaaggctacg aagaccgtga acgctttatt
    20221 atcttgcaga aagtcggttt ggaccaaaag caaatcaagc aaaccatcaa caaacaggtt
    20281 ttaactgttt tcttccttcc tttgctcttt gccttcatac atctcgcctt tgcctaccat
    20341 atgcttagcc tgattttaaa agtgattggt gtactggata cgactatgat gttgattgtg
    20401 accttgtcta tctgcgctat cttcctcatc gcctatgtgc tgattttcat gattacttca
    20461 agaagttatc gcaagattgt gcaaatgtaa aaaagatacc tcgacttcaa aatcgaggta
    20521 tttcttgtat tctaaatgct gaaaagttgt tcgagcagga aggtaactcc catggtcaag
    20581 agaccaatag caaggttccg aatcatagct gttctagtcg gatcctttcc aagtctggca
    20641 ctagtgtaac cagtgagaag aagggccaca ccgacaataa ggacagtagc agggatgcga
    20701 tattcacttg ggaatatggt cactgacagc attggaggca aacttctaag gaaaaaggca
    20761 acgaagctag aaatggcagc gtgccaagga ttggtaaatt cttcatactc aatcccatat
    20821 ttttcctcta ccagagcctt gagtggattt ttaagaaaga tcttattggt caagagttgg
    20881 gcagaagttt tgcattctcc attttggata taagcagcat agagggattt tttggctagt
    20941 tccctatctt ggtctaacaa gagtttttct cgcgaaacgg cagcttcctc ggtatctttt
    21001 ggagttgaaa cggatacata ttctccacca gccattgaaa aggcaccagc taagatagcc
    21061 gcaaatcctg ataaaaagat aatccagata ttggtcgtgg cactggcaac cccgataacc
    21121 acaccagcaa tggaaataat tccatcgtta gcaccaagaa cacctgcgcg caggatattt
    21181 aaacgacctg caaaatttga atcgatttcg tgatttgttt ctgacgctaa atttcaagtt
    21241 caagttagcc atcaagaagt cttctctggg tgacttgtag ttcaagcatt ttttaggata
    21301 gttgttaatc cacttttcga tgaatgcgac ttctttggga gtcattttct tggttccctt
    21361 aggtaaccat ctacgaatga gcctgttgtg attctcatta gttccccttt cccaagaggc
    21421 ataggggtgc gcataataga tgtgctcctc agaaaataca tcaaacaagc gattgaattc
    21481 cgttccatta tctgccgtga tggaaagaat cttgtgttgt tttaagatga gttttagagc
    21541 ctgattgacc acctcagcac ttttatttgg aatcaatcgg atgatctgat gtctactctt
    21601 tcgatccgtc aagacaagca agcagtagtt tttcgctctc gtaagtagaa ccgtatcaat
    21661 ctcataatgc ccattctcca agcgaagatt gatagcttca ggccgctgtt cgatggattg
    21721 accagcaggt ttaaagttgg tgctagcctg tttcttaagc gcttttcctt ttctagggta
    21781 aagcaaatcc tgcttgctta accccaattt tccatgatga atccaatagt aaatggttga
    21841 aattcccacg ttaacccctt tagccataac catcatttca ggcgaaaatt tttggttatg
    21901 atagtggaga atcttttcct ttagttcctt ggtcaagctt gatttcttga ccgagcgctt
    21961 gcgattgttt tcataagact gttgagcata gtcggcagaa taaacctctt tgaagcgccc
    22021 ttttccaaga cattgtcgga ctgtcccacg cttgatttca gtgtggatag tttgaggagc
    22081 ttttccaagt agagaggcaa tttctctatt tgatttccct tcttttttcc atctttcgat
    22141 taagcgacgg ctatcgattg tcaaatgttt ggcttttgta gtataattgt cttgcatctc
    22201 tgtgcctttc ttgtgtttgt ggttgaacaa caagtataac acagaggtgt tttcttatgc
    22261 ctacaagagc tatcagctag ttgaaccatc taatttttag gagggctggg tggctaactt
    22321 cattatagaa ctttcattta cgaacatata gtaaaatgaa acaagaacag aacaaatcga
    22381 tcaggacagt aaaatctatt tctaataatg ttttagaagc agaagtgtac tattctagtt
    22441 tcaatctatt atatttttgt tttttatcaa aaaatacttt acaagttctt aaaaacatga
    22501 tatagtaata aagcttagaa aatgagatga tgttttctag caaatataaa cccgagtaaa
    22561 aaatgcctac ggacaggcag ggttgaatgc cgaagcgtgg ttgaaaagcc acattattga
    22621 tagggttaaa agcctacttt tataagttga tgttaggaca cttgtcctaa ttcataaatt
    22681 tttagtgtgg tgaaagcaca cgtcatcttg tgaaacgatc aataaagtac gtaatatttg
    22741 ctactagaga gttaggaaac atcgggaaca gacatactca acagaaacca aaataaacac
    22801 gtcagaagat tgcagagcag gtgaaaacct gctctttttt catgagtcaa cctttagttc
    22861 cttagttttc ataaggtcct aaaaatattg aaaggagtat gttttgaaag agttagatca
    22921 aaaccaagcc ccaatttatg aagccttggt gaagttacgc aagaaaagga ttgttccctt
    22981 tgatgttcca ggtcacaagc gtggacgggg aaatccagaa cttgtcgaac tcttaggaga
    23041 aaaatgtgta ggcattgatg tcaattcgat gaaacccttg gataatttag gccatcctat
    23101 ttcgattatt cgtgatgcag aggagctggc tgcagatgct tttggagcta gccatgcctt
    23161 tctaatgatt ggtggaacaa cttcatcggt gcagactatg attctggcaa cctgcaaggc
    23221 aggagataag attattctgc cacgaaatgt ccataaatct gctatcaatg cgttggttct
    23281 atgtggtgcc attcccatct atatcgagat gagtgtagat cctaagattg gtatcgcttt
    23341 aggtcttgaa aatgaccgag tagcacaggc cataaaggac catccagatg ctaaggctat
    23401 cctaatcaac aatcctactt actacggcat ctgttcagac ctaaaggggt tgacagaaat
    23461 ggctcatgaa gctggcatga tggttttagt agatgaagcc catggagcgc atttgcattt
    23521 cactggtaaa cttccaattt ctgctatgga tgcaggagct gatatggcag cagtttccat
    23581 gcataagtct ggtgggagtt tgacacaaag ttcgcttctt ttaatcgggg agcagatgaa
    23641 tcccgagtac gttcgtcaga ttataaacct gacccagtct acatctgcct cttacttgtt
    23701 gatggctagt ttggatattt cacgtcgcaa cttggccctt cgtggtaaag agtcgtttga
    23761 gaaagtcatt gagctatctg agtatgcccg ccgtgaaatc aatgctatcg gtggctacta
    23821 tgcctactca aaagaattaa tagacggtgt ttcggtttgc gattttgacg taactaagct
    23881 gtcagtttac actcagggta ttggcttaac aggtatcgag gtttatgacc tcttgcgaga
    23941 cgaatacgac attcagatcg agtttggtga tatcggcaat atcttggcct atatttctat
    24001 cggcgaccgc atccaagaca tcgagcgctt ggttggtgct ctggctgata ttaagagact
    24061 ctattcaaga gatggaaaag atttgatagc aggagaatat attcagcccg agttagtgct
    24121 gtctccgcaa gaagccttct attcagcaag aaaaagttta actttggatg attctgttgg
    24181 acaggtttgt ggagaatttg tcatgtgcta tcctccaggg attcctatct tggctcctgg
    24241 tgaacgcatt acacgagaaa ttgtcgacta tatccaattc gccaaggaac gtggttgctc
    24301 cctccaaggg acggaagatc cagaggtcaa tcatatcaac gttattaaga gaaagacaaa
    24361 ctataagaaa agtcaatagt tttatctaaa ctatttctta tttcaatttg atgatttggc
    24421 gatgatttta gagcacggca aaaagccctt gaattagaag cggtcaatcg cttaatttct
    24481 atcagcttat caaatcctgc ctcaatcctt ttctgaggat tagggtagcg tgtcaagagt
    24541 tggtaggtat attctgaatg ctttccaacg attttatcca actcaggaaa gatgatatca
    24601 agacaacgag tgtattgtac tttccaatca gactgttttt tcttgagacg atgaatatgt
    24661 ctagtcagta tttttagttc tacttgccga ttatcgtgtt gaaattgttc acgattgggg
    24721 tcagaaagaa gtttaagagc gatgccatga gcgtctttct tattcgtttt agtcttgcga
    24781 agtgataatg atttggcaaa ttccttgatg agcaaaggag tgtaggtgta aactttatat
    24841 ccttgttcat gcaggaagtt cagtagatta aaggcataat gtccagtatc tt
//
LOCUS       DAVLGK010000034        23322 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLGK010000034 DAVLGK010000000
VERSION     DAVLGK010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23322
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.034"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(547..717)
                     /locus_tag="VXE01_001507"
     CDS             complement(547..717)
                     /locus_tag="VXE01_001507"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0750390.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEKAG"
     gene            complement(1534..2757)
                     /locus_tag="VXE01_001508"
     CDS             complement(1534..2757)
                     /locus_tag="VXE01_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0750391.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            2925..4247
                     /locus_tag="VXE01_001509"
     CDS             2925..4247
                     /locus_tag="VXE01_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0750392.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMVVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            4249..6135
                     /locus_tag="VXE01_001510"
     CDS             4249..6135
                     /locus_tag="VXE01_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV0750393.1"
                     /translation="MVIRVFDKQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRRDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEISGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQSDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            6303..6647
                     /locus_tag="VXE01_001511"
     CDS             6303..6647
                     /locus_tag="VXE01_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0750394.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            6657..8069
                     /gene="lacG"
                     /locus_tag="VXE01_001512"
     CDS             6657..8069
                     /gene="lacG"
                     /locus_tag="VXE01_001512"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0750395.1"
                     /translation="MENLQFKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGDANILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLDRENIDHFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKTGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            8138..9817
                     /locus_tag="VXE01_001513"
     CDS             8138..9817
                     /locus_tag="VXE01_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0750396.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIVWMRKVYMLTMGVLGIIVSGTVGKSLVGNVNRKMPHGKV
                     INDTSAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QPISFVLLSLMLVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            complement(9942..11381)
                     /locus_tag="VXE01_001514"
     CDS             complement(9942..11381)
                     /locus_tag="VXE01_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0750397.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLIFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(11385..12734)
                     /gene="trkA"
                     /locus_tag="VXE01_001515"
     CDS             complement(11385..12734)
                     /gene="trkA"
                     /locus_tag="VXE01_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV0750398.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIEREHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            12923..13771
                     /locus_tag="VXE01_001516"
     CDS             12923..13771
                     /locus_tag="VXE01_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV0750399.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            13786..14334
                     /locus_tag="VXE01_001517"
     CDS             13786..14334
                     /locus_tag="VXE01_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV0750400.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            14341..14553
                     /locus_tag="VXE01_001518"
     CDS             14341..14553
                     /locus_tag="VXE01_001518"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750401.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDETDEVSNHTYGKAKLTWFEEI
                     FEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            14655..16337
                     /locus_tag="VXE01_001519"
     CDS             14655..16337
                     /locus_tag="VXE01_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750402.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRII
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            16322..17152
                     /locus_tag="VXE01_001520"
     CDS             16322..17152
                     /locus_tag="VXE01_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0750403.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            17345..17848
                     /locus_tag="VXE01_001521"
     CDS             17345..17848
                     /locus_tag="VXE01_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV0750404.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      17902..18136
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            18301..18864
                     /locus_tag="VXE01_001522"
     CDS             18301..18864
                     /locus_tag="VXE01_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0750405.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            18878..19504
                     /locus_tag="VXE01_001523"
     CDS             18878..19504
                     /locus_tag="VXE01_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0750406.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKEPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            19532..19921
                     /locus_tag="VXE01_001524"
     CDS             19532..19921
                     /locus_tag="VXE01_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV0750407.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            19926..20375
                     /locus_tag="VXE01_001525"
     CDS             19926..20375
                     /locus_tag="VXE01_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0750408.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            20503..21090
                     /locus_tag="VXE01_001526"
     CDS             20503..21090
                     /locus_tag="VXE01_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV0750409.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            21480..23087
                     /locus_tag="VXE01_001527"
     CDS             21480..23087
                     /locus_tag="VXE01_001527"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV0750410.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         6954 a         3909 c         5084 g         7375 t
ORIGIN      
        1 aattagctcg tatctatagg atgatactga aaatcttctt gttgctttaa atcacaatcg
       61 aaaaattctg tttttcatct tagaaaagaa tgtttagaaa tgtaaaatga atcttttttc
      121 ttatccgaaa acattactaa agtatataat ttaggaagtc aattctgtat gataatgttt
      181 gtactatcgt cgagtttttg cttgattgcc taacgagata aattttagaa gaattttcgg
      241 tgtgatttga caagcttctg actggaagga tagttacact agtattgttt attaaaatga
      301 gcagatagag aaaatttgga atctatttgc ttattatcaa tcgttttttt agcttatttg
      361 tcttagattg gtatagaact gatctatgga ttaatcctct tgtatcttat cctgttccta
      421 aatatgttgg tagaaaaatg aagcagttgt tacgagtgtc tgtattggga aaaattttgt
      481 ctatacaatt ctttaaatga tatgaaggct aggaatgcca aaacactgac atatttcgtt
      541 taaagcctat ccagcctttt caattgtatt tgtagaaatg ctatcagtaa tatattcgcg
      601 aacactatga tttacaacag tgtggtcgta catctttgta actttattat acaacaacca
      661 tttacaggtg taaagttgag cagtgtcttt agtaaattta gggacttgtt ttgtcatagt
      721 tttgatacct gtattcgttg tttcatgagc atttgacgtt tcttttcatg taggcatttc
      781 aacaattaga atgatatttt tccgaggatg aacttatata ttgtgacttt ttagagttat
      841 gatgcctctt gatttgacta tcgctatcaa tttcatccac ttttacagtt tcatggtttt
      901 atgaaccgaa acatctaggt acaggtttta gcatcaattg attgtttttg agccatatga
      961 agttgaaacg tggagatgct tttcttgtga taacgcccta ttcaaagagg cataaccgtt
     1021 tttggagaga gttcagtact atgtggcgct aaataatata tgtaaaatag tatggtgtag
     1081 agatattaaa caagatttaa ctaatacttt tcgaaaatct cttcaaacca cgtcagcgtc
     1141 gccttaccgt atagatgtta ctgacttcgt cagttctatc tacaagctca aaacagtgtt
     1201 ttgagcagcc tgcagctagc ttcctagttt gctctttgat tttcattgag tatacggaga
     1261 attgtaaaaa caaaaatggg gatttcatat aaagtttatt ctaggagtat gtatcttgaa
     1321 taaaaattgt tatttaagtt ctgggggtta tgatgaatgt ttttataata ataaaatgca
     1381 gctagaagaa aagttatttt aatataaatc actcaacata gcgagaaggc ggtttcctat
     1441 atggaagtcg tcttgttttc atattgtcta aatacgagat atctactaca ggttatagtt
     1501 gatttaaaca ggtgtataga tttctaatat atattaaggt gaaataatat cttgtaatac
     1561 attgctatgc tctatgaaaa aagcaacgat agctaatgca caagctccta tacttccacg
     1621 atgtttgttg taaggtaaaa tttcaatttc tatattacga gtaaagggaa cgaagtggag
     1681 ctggtcttgg attttatccc tgacttcatg agtgaaaggt tgataattaa gcaattgact
     1741 gttgatatag attttatcag caggattgat gaggagaaga tttgcaatag aagtggccaa
     1801 taaattgact cctttatcaa tttgttggcg taaagcggag tcgcctaaat tataagccgt
     1861 taaaagggtg tctaaatgaa tgtctttttc agtctttaca aggcttttta gtacagttag
     1921 ttgggaattt ttaaataata attgggcgtg tttgattaac caagcatccg aaatatatgt
     1981 ttgtaaacaa cctttttttc cgcattcaca atattgccca ttcaattcga caatggtgtg
     2041 tccaatttct ccgatataag gatttttaga ggctcctatt ttttcttttg tgaaaaagga
     2101 agtgtaaata cctaatccag cgtgtaggaa aataaagtta tcgggggtat tgtgtggatt
     2161 aaaaaggtat tgtcctatag ccatacaatc gatattattt tttacaataa aaggaaaatt
     2221 gaatctttta attacattta ataaattaaa agattcccat atggggttgt ttgtaatgat
     2281 acttccggag tctttgttat aatgtccagg tattgataag ccaaatccaa gtaattttgt
     2341 ttccaaaggg acgtactcta tagctgtttt tatcatattg gtaatggtgg aattgatttc
     2401 tgaaatagga taatcttcat tcaaaatttc tgtctcgaaa agagttttcc cttgtaagtc
     2461 acatagactg agaaagatac ctaggacgtt tatttcaata cctccaacaa catacggaat
     2521 attatctgtg atagaaatag tttttctacg tcttccagat ccggaaaact cgctaaattc
     2581 atcaccagtt tcgtatatga gggactgttc gcttagctct tttatgatgt tagtcgttgt
     2641 tgctggagta aggcctgttt cattaacaat atctgtacgg gatgttgctg gatttcgata
     2701 tagaaactcc agtatagtgg ctctattttg taaaaaggct gattgttttg taatcatttg
     2761 tttcctcctt tggtttattt tatattaaac ataagaaaaa atcaattaaa attattattc
     2821 tatacaaaga aaaaaatatt gtaaaaacaa caaaaaatat attgacaacg ctttctgtta
     2881 gtggtatatt taatttataa aaaataaaaa aaggagttcc ggtgatgaac aatattttag
     2941 cgtttttaga aacaaaagtc gctccgtttg gtgaaaaagt tggcaaccaa cggcatttga
     3001 aagctattcg tgaaggattt atgatggcaa tgcctttgat tttagtcggc tctttatttc
     3061 ttattctaat cagttggcct caagaggatt ttacaaattg gctgaatagt gttggattgc
     3121 taagtatctt gacaactatg aatcagtcaa cagtagcgat tatctccttg gtcgcttgtt
     3181 tcggtattgc ctacaggttg tcggaaggat atggtacaga tggtccgtcg gcagggatca
     3241 tagccttatc cagttttgta ttgatggcac ctcgtttttc gagtatggtt tatgataaaa
     3301 atggggagca ggtcaagcag ttatttggcg gcgcaatacc attttctagc ctgaatgcat
     3361 cttctttgtt tatggcgatt actattggat tggttacagc agagatttat cgtatgttta
     3421 tccagcgcgg aattacgata aaaatgccaa gtggtgtccc agatgtggta agtaaatcat
     3481 tttcagctct tttacctggc tttactactt ttgttttgtg ggctctggtc ttaaaaggtc
     3541 ttgaagcggc aggagttgca ggaggtctca acggactcct aggtgcaatt gttggaacac
     3601 cgcttaagtt aattgcagga acgcttccag gtatgattct atgtgttatt gtaaactcat
     3661 tcttttggtt ctgtggagtt aatgggggac aagttttaaa tgcttttgta gatccagttt
     3721 ggttacaatt tactacagaa aaccaagaag ctgtggctgc aggacaaaca ctccaacaca
     3781 ttattacatt accgtttaaa gatttatttg tatttattgg tggcggtgga gcgactattg
     3841 gtcttgcgat ttgtctcttc ctatttagta agagtcgtgc gaataaaaca ttaggtaagc
     3901 tagctattat accgtctatt tttaatatca atacagctat tctatttacg tttccaacag
     3961 ttttaaatcc gattatgctg attccgttta ttgctactcc tacaatcaat gccttaatta
     4021 cctatgtatc aatggttgta ggattagtac cctatacaac aggtgtaatc cttccgtgga
     4081 caatgccacc gatcatagga ggcttccttg cgacaggagc tagttggcga ggagctctat
     4141 tacaagttgt tttgattttg gtttctgtag caatttatta tccattcttc aaaattgcag
     4201 ataaacgcaa tcttgaaaaa gaaaaagcta ctgttggagg gaaataagat ggttatcaga
     4261 gtatttgata agcagaaaaa tacttattct agctttgcct tagaggaatt aagttactat
     4321 ataaatcggg tctttaagac tgacatagaa cttgtcgagg agaaggaagc ggatattttt
     4381 gtaggattag tcaataaaga ggatagaaga gaccatgttc ttatctcatt agacaagggt
     4441 aaggggagaa ttgagtctaa tacaattgta ggtttactta ttggaattta ccgaatgttt
     4501 catgaatttg gggttgtgta tactagacca gggcgcggac atgactttgt tccagagtta
     4561 cgatttgaag attttttaga taaacagcta tctatagatg aaacagccag ttactatcat
     4621 aggggagtat gtatagaggg agcggattca tttgaaaata tactagattt cattgattgg
     4681 ctacctaaga ttgggatgaa cagttttttc atccagtttg aaaatcccta ctcttttttg
     4741 aaacgttggt atgaacatga atttaatcca tatctaaata aagaacaatt ttcaaatgaa
     4801 ttagtacaag aattgagtga taggttggat aaagaattgc aaaaaagagg tcttattcat
     4861 catcgtgttg gtcatggatg gacaggtgaa gttttaggtt actcttcaaa atttggctgg
     4921 gaatcaggtc ttagtatttc agaggagaag aaaccctatg tcgctgaaat aagcgggaaa
     4981 cgagaattat ttaatacggc tccgatttta accagtctgg atttttcaaa tccagatgtg
     5041 gcggataaga tggtagaaat tatcaaggat tatgccaaga aaagacctga tgttaactac
     5101 ttacatgtat ggttgtcgga tgctcgtaat aatatttgtg aatgcgaaaa ctgtagacaa
     5161 gaattggttt cggatcagta tattcgtatt ctcaatcaat tggatagggc tttaacgagt
     5221 gagggattag atacaaagat ttgttttctg ctttaccatg agttgctatg ggcgcctcag
     5281 aaagaaaaat tagataatcc tgaacgcttt accatgatgt ttgcaccgat tacaagaaca
     5341 tttgaaatga gttatgcaga tgtagatttt gacaattcca tacctacgcc taaaccttat
     5401 ctgcgtaata aaattatact tccgaattct cttgaggaaa atttatctta tctttttgag
     5461 tggcaaaaaa catttaaagg agatagtttc gtatatgact atcctttagg gcgtgctcat
     5521 tatggcgatt taggctatat gaaaattagt caaaccattt acagagatgt atcttatctt
     5581 tctaacctac atttgaacgg ttacatttcg tgtcaagaat tacgtgccgg attccctcat
     5641 aattttccta attatgttat gggggaaatg ctctggaaga agacaagaag ttatgaagaa
     5701 ttgattgaag aatacttttc tgctttgtat ggggaaaatt ggcagtctgt tgttgaatat
     5761 ttagaaaaat tatccattta ttcctcttgt gattatttta atgcaattgg cagccgtcaa
     5821 agtgatgttt tagcgaatca ttattatata gcttacaatc tagctgataa ttttttacca
     5881 attattgagg aaaatatttc taagttatta aatagtcaaa aggatgaatg gaaacagctc
     5941 agttatcatc gtgaatatgt tgttaagatg gcgaaggctt tatatcttca agcaactgga
     6001 aaaacaaggc aagctcaaga tgaatggaga aatgtgttga attatatccg tgggcacgaa
     6061 ttgctatttc aatctaattt ggatgtttat cgtgtaattg aagtagcaaa aaattacgct
     6121 ggtttccact tataaatcat aagtatagaa aatgaactaa ggtattcaga gaagattgac
     6181 cctaaatatt atgaaattta aggattttta agatatttag ggtcgacttt ctatttgtat
     6241 cgtagcgaag tcattttaat aatgatgtgt aaaagatgga tcaagattga ggaggaagaa
     6301 agatgaaatc aaaagaagaa ataaatatgc ttggttttac aattgtcgct tacgcaggag
     6361 atgcaaggtc agatttgatg gatgctttgg cgtttgcgag agatggatat tttgaacagg
     6421 caagagaatt ggttgagtct gcaaacgact caatagtgtc tgcccatcga gaacagacta
     6481 atttattagc agaggaggca tatggagata attttgaagt gagctttatt atgattcatg
     6541 gtcaagatac tttgatgaca acgatgctat tgtatgatca ggtaaagttt tttattgatg
     6601 aatatgaacg aattcgaaag attgaagaac atattggttt gcaatgagga ttagtcatgg
     6661 aaaatttaca gtttaaagcc ttaccgaagg agtttttatt aggagctgct accgctgctt
     6721 atcaagtaga gggtgcaact agggtagatg gtaaaggaat aaatatgtgg gatgtttatt
     6781 tgcaagaaaa tagtccgttc ttaccagatc cagctagtga tttttattat cgttacgaag
     6841 aggatatagc tttggcggca gaacatggtt tgcaggcttt gcgtttatct atttcttggg
     6901 ttcgtatatt tcctgatata gatggagatg ctaatatatt ggctgttcgt tattaccata
     6961 gagtctttca gtcttgctta aaacataatg tgattccgtt tgtttcttta catcattttg
     7021 attcgcctca gaaaatgtta gaaacagggg attggttgga tagagagaat attgatcatt
     7081 tcatacgata tgctcgcttt tgtttccaag aatttacaga agtcaagcat tggtttacaa
     7141 tcaatgaact gatgtctctt gctgcaggtc aatatatagg aggtcagttt cctccaaatc
     7201 atcattttca attatctgaa gcaattcaag cgaatcataa tatgttgttg gcgcatgctc
     7261 ttgcagtcct cgaatttcat caattaggaa ttgagggaga gataggttgt attcatgctt
     7321 taaagccagg ctatcctatt gatgggcaaa aagaaaatat tttggcagct aaacggtatg
     7381 atgtttataa taataaattt ctattagatg gaactttttt gggctactac agtgaggaca
     7441 cgctttttca cttgaatcaa atattggaag ctaataattc tagctttatt attgaagatg
     7501 gtgatttaga aattatgaag agagctgcac ctcttaatac gatgtttggg atgaattatt
     7561 atcgttcaga atttattcgt gaatacaaag gtgaaaatag acaagaattt aattcaacag
     7621 gaataaaagg acagtcttct tttaaattaa atgctctagg tgaatttgta aaaaaaactg
     7681 gtattccgac aacagattgg gattggaata tttatcctca agggttattt gatatgttgc
     7741 ttcgtatcaa agaagaatat cctcaacatc cggtcattta tttaactgaa aatggtacag
     7801 cccttaaaga agttaagcca gagggcgaga atgatattat tgatgacagt aagagaatcc
     7861 gttatattga gcaacattta cacaaagttt tagaggctcg agatagagga gtcaatattc
     7921 aaggctattt tatatggtct ttgcaagatc aattttcttg ggcgaatggc tacaataagc
     7981 gatatggtct tttctttgtt gattatgaaa cacagaagag atatattaag aaaagtgctc
     8041 tttgggtaaa agggctaaaa cggaattaag gttagcgatt tgactgatgt ttaatatgtt
     8101 ttaaatatga ggttgaattt tttataggag gagttttatg gataagctag tcgctgccat
     8161 tgaaaagcaa caagggaaat ttgaaaaaat ttctactaat aactatatga tggctattaa
     8221 agatggattc attgctacta tgcctttaat tatgttttca agctttttga tgattattat
     8281 tatgattcct aaaaatttcg gagtagagtt accgagtcca gctattgtct ggatgagaaa
     8341 agtgtatatg ttaaccatgg gagttttggg tattattgtt tcagggactg ttggaaagtc
     8401 attagttgga aatgttaaca gaaaaatgcc tcacggaaag gtaataaatg atacttctgc
     8461 aatgttggca gccatatgta gttatctggt attaactgta acgcttgtag ttgatgagaa
     8521 gacgggatct acaagtttgt cgacaaacta tttaggatct caaggattga taacttcgtt
     8581 tgtcagtgcc tttattactg taaatgttta ccgattctgt attaagcgag acattactat
     8641 tcatttacct aaggaagttc ctggggctat atcacaagct tttagagata tttttccttt
     8701 ttcttttgtt ttacttatta gtggtttgtt agatattgta tctcggttta gtttagatgt
     8761 tccttttgcc caagtatttc aacaactatt gactcctatt tttaaggggg cagaatcata
     8821 tcctgctatg atgttgattt ggtttatgtg tgctttgctt tggtttgttg gaattcatgg
     8881 accatctatt gtcttacctg ctgttacagc tttacaactg agcaatatgg aagagaatgc
     8941 tcaacttctt gcaaatgggc agttccctta tcattcttta acacctaatt tcgggaatta
     9001 tatcgctgct attggaggaa cgggggctac ctttgttgta ccatttattt tgattttctt
     9061 tatgcggtct aaacaattaa aatcggtagg taaagctaca attactcctg ttttatttgc
     9121 ggtaaatgaa cctcttctat ttggtatgcc tgttattttg aatccctatc tttttgtccc
     9181 ttttttgatg actccaccag taaatgtatt tctaggaaag gtatttattg atttctttgg
     9241 aatgaatgga ttttatatcc agttaccttg ggcttttcct ggtcccttgg gattgttaat
     9301 tggaacgaat tttcaaccta tctcctttgt gcttttatct ttgatgttag ttgtcgacat
     9361 attgatttat ttgccattct gtagagcgta tgatagacag ttactgatga aagaagatgt
     9421 tgcaagctca aatgatatta ttttagagga ggatacaagt gaaataatgc ctggtgagat
     9481 agatgtaata aaaagtaagg agttgaaagt actggttctt tgtgcagggt ctggaacaag
     9541 tgcgcaatta gccaatgcaa ttaacgaggg cgctcaatta gcagaagtta gagtgattgc
     9601 gaattcagga gcgtacggag ctcattatga tattatgggt gtttatgatt taattattct
     9661 ggctccacaa gttcggagtt attatagaga gatgaaggtg gatgcagaaa gattaggtat
     9721 tcagatagtt gctaccagag gaatggaata tattcattta acaaagagtc caagtaaatc
     9781 cttacaattt gtattggagc attaccaagc tgtgtagtaa gtttttccat cttttatttg
     9841 agtaagaact ttgcttacag acaggcttgg atttaaaaac gttccccctt tttaatataa
     9901 aaatccctct ttcacaattg taaaaagagg gattttgtat tttatctttt agaccaagtt
     9961 ctcttcataa agagaagtag gattgggtaa atctccaagc ggcctgcaat cattgcaaag
    10021 gagaggagaa tttttgagat aggactaaag attgagaaac tagaagtggt tcctagaata
    10081 ggcccgatat tattgaaaca gctaaagaca gcgctggtca cgatcagaaa atcattgcta
    10141 tctaggctga caataaagat aagggatagc aaaatcatag catagatgac aaagtacttg
    10201 agaattttat gctgggtatc cttatcaatc accgttttat tcacatggag agtcaaaaca
    10261 cggtggggag atagaatgga caaaatttga tttttggcaa tttttgaaag gatgaggcct
    10321 cgaataatct tgagtccacc tgcagttgat ccagcagaac caccgattgt catgaggaag
    10381 aggaggataa actgggagaa gaggggccag ttggtaatat ctccatatcc aaaaccagtt
    10441 gttgtaatga tgttggaaac ctggaagaag gtcatttcaa agctctttga aaaccctggg
    10501 tagaggtaga gggtgttgag gctaatcaag cctgtagaaa ccagtacaat gaccaagtaa
    10561 gcccgaagtt cttcgtcacc aaagaaggcc ttgatgcgac ggagcatgag gtagtagtag
    10621 aggttgaaat ttaccccaaa aatcagaact ccgatactga ccagataggt aatcagtgag
    10681 ctgccatagt gggcaattcc gtcgttatag acggtaaagc ctccagttcc cgctgtcccc
    10741 atagcaatga caaaactatc gtagagaggc ataccagcta gataatagat gatgacaaag
    10801 agggagaaga gagctagata aaggagatag agaatctggg cagtgttttt tagtttggat
    10861 acaaccttgc caaaaacagg acctggaacc tcagccttca tcacctctag gtggctattt
    10921 ttggcattgt ccataatagc aagtgcaaaa acaagcactc ccatccctcc aatcaagtgg
    10981 gtaaaacttc tccagaagag gagggaacgg ctgagaaccg aaacgtcgtt caaaatactt
    11041 gctccagtag ttgtaaaccc agaactaatt tcaaaaaagg catcaataac gctagggatt
    11101 tgcccagaaa agacaaaggg gagaccacca aagaaagacc aaaggatcca acagagggca
    11161 acgatcaaga ctccctcctt ggcataaatc cgttgatttt ttggcttctg taaactccct
    11221 gaaccgccta acaatacgag aatccctatg gtcgaaaaga gggccgtaaa gacttggctc
    11281 gattcacggt aatagacagc gatagccaca ggaaccaaga ggagaacagc ttcaatcaaa
    11341 agtaactttg aaaggaggta acgaatcata cttttattca ttttttacct cgcaatcaag
    11401 tcataaatct tggtgatgtt tggcaacaag gttgttacta ggagcttgtc tccaacttcc
    11461 aacatatcct ccccagttgg gaaaatagtc ttgccctttc gaataatggc tgcaataaga
    11521 accccttttt tcaatttcag ttgagaaaga ggtttggcag tcattttatt ggcttccttg
    11581 atatggaatt gcagggtttc gatttggcca ttggctagat ggtgcatggc ttgaaggtct
    11641 gaatactggg cattaactcg accacgaata aagtgcataa tcgtatctac agcgatgctt
    11701 ttaggtgtga tgatacttga aaaatcaggc gcattgataa tctcgaggag actggtacga
    11761 ttgaccttag taatattttt ctgtacacct accctgtcaa ggaacataga tgtaatcaga
    11821 ttttcctcat cgacacctgt tagagtcgca acggcatcat agtgttgagc actttcttcc
    11881 agcaggatat cttttgcggt tccatctcct tgaacgatgt agagatttgg gaatttctcg
    11941 ctaaagaagc tggcgatttc aggattgatt tcaatgactt ttgtatcgat acgactatct
    12001 ttgagaatac caagtagata ataggcaatt ctacctgccc caacgatgag aaggctcttc
    12061 acggcgcgtg atttaaaata attatggaag agtatcatat cgacacggtt accagtgaca
    12121 aagattctat ctttatcctg tacagtcatg tcaccgcttg gaatgataat ttgatgctcc
    12181 ctctctatcg cacagacaat gacattacca aattttttac gaaaatcaga aatgggcatt
    12241 tggcaaagac cgctggtgga cttgacgaca aattccatga ggctaacgcg tccaccagca
    12301 aagcgttcga cagacagggc gttggggaag tcaatgatat tcgcgatagc gcgggcagcc
    12361 aagagctcag gattaacgat aagagaaaaa ccgagaatat tcttttcctt gaaataagag
    12421 ttagaatatt cagggttccg cacccgaacg atagtttctt tagctcccat tttcttggct
    12481 agaactgctg caatcatgtt gacttcatcg tgctcagtca gggcgataaa gatatcacaa
    12541 tcttggacgc tggcttgctc aagaatggca aaatcggccc cgttaccaag gataccaatg
    12601 atatcaaagc gactgacaat atgattgaga acagcttcgt cttgctcaat cagcaaaaca
    12661 tcatgctttt ctgcaaccaa ggagcgacag agggcaaaac caacttttcc ccctccgaca
    12721 aggataattt tcataataaa acctactttt tcatgatgta actatcatac cctttttcaa
    12781 gaaaaaatgc acctactagc taataaccag agtttttagt aggaaatttg ctataagtta
    12841 aaactatacc ctaaccaatt gaaatagcta ttagcgactt tctctgaaat atggtatgat
    12901 aaaggatata caaggagata aaatgaataa taatttactg gtattacaat cagactttgg
    12961 tctggttgat ggtgcggtat cggctatgat tggagtggct ttagaagagt ctccaacctt
    13021 aaaaatccat cacttgacgc acgatatcac gccttataat atttttgagg ggagctatcg
    13081 tctctttcag acggtggatt actggcctga gggaacgacg tttgtatcgg ttgtcgatcc
    13141 aggtgtcggt tcgaaacgta agagtgtagt tgccaagact gcaaaaaatc aatacattgt
    13201 cacgccagat aatgggacgc tttcctttat caagaaacac gttggcattg tagccattcg
    13261 tgagatttct gaggtggcca ataggcgtca aaacacagag cattcttata ccttccacgg
    13321 tcgtgatgtc tatgcctata ctggtgctaa actggccagt ggtcacatta cttttgagga
    13381 agtagggcca gagctcagtg tggaacagat tgtagagctt ccagtcgtag cgaccatcat
    13441 agaagatcat ctggtgaagg gagccattga tattctggat gtgcgtttcg gttcgctttg
    13501 gacctctatc acacgggaag aattttacaa gctggaacca gaatttggtg atcgttttga
    13561 agtgaccatc tatcatgctg atatgctggt ctatcaaaat caggttgtct atggcaaatc
    13621 atttgcagat gtgagaattg ggcaacccat cctttacatc aactctctct atcgtttagg
    13681 tttggctatc aaccaaggtt cctttgccaa ggcctataat gtaggtgtcg gttcatcttg
    13741 gaccattgaa ataaagaaaa tagaaggata aaataggaga atagtatgga aatcaaattt
    13801 acaattaaac aagttgttgc tgtcggaatt ggcgctgccc tctttgtcgt catcgggatg
    13861 atcaacattc caacccctgt tccaaataca agcatccagc ttcagtatgc ggtacaagcg
    13921 ctactttcta ttatttttgg accgattatc ggtttgcttg tcgggttgat tggtcatgca
    13981 atcaaggact ctcttgttgg ttatggtcta tggtggactt ggattatcgc tagcggactc
    14041 tttggtttag ttgtgggact ttttagaaag tacgttcgcg tgatcaatag tgtttttgac
    14101 tggaaagata ttcttatttt taatctcatt caactacttg caaatgccct tgtttggggt
    14161 gtcttggcac cacttggaga tgttgtgatt tatcaagaag cggcagaaaa agtatttgca
    14221 caagggattg ttgcgggaat tgccaatggt gtatctgtag ctattgcagg aactcttctc
    14281 ttacttgcct atgcaggaac ccaaactcgt gcaggaagtt tgaaaaagga ctaatactca
    14341 atgaaaatca aagagcaaac taggaagtta gccgcaggtt gctcaaaaca gtgttttgag
    14401 gttgtagatg aaactgacga agtcagtaac catacctacg gcaaggcgaa actgacgtgg
    14461 tttgaagaga ttttcgaaga gtataaaatg atggggaagg ctgggcaact agtctttttc
    14521 gatgtttata gattagttag gcaagtaagc taggatagga atctttttgg cgctaagatt
    14581 ttaagagaag agactgcaag aagggcttga tttatgataa aatagaagtc taagaagcga
    14641 atgaagagag taagatgaaa gaagctataa ttgagtggaa ggatttctct ttccggtatg
    14701 aaacacaaca agaaccgacc ttgcaaggga tagacttgac catttacaag ggagagaaag
    14761 tcttaattgt tggaccatct ggatcaggta aatctacctt gggtcagtgt ttgaatggga
    14821 ttattcccaa tatttacaag ggtcagacat atggagaatt tttgataaag ggtcaaacag
    14881 cctttgatat gagcatctat gataagtctc atctggttag cacagttttg caggatacag
    14941 atgggcagtt tattggcttg tctgtggcag aagatttggc gtttgctctg gaaaatgatg
    15001 tgacagccct agatgagatg aaaggtcgtg tttataaatg ggctgaaaag ctggaccttc
    15061 ttcctttact ggatcagcgt cctcaggatt tgtcaggtgg acaaaagcag cgagtcagtc
    15121 tagctggtgt cttgattgat gaaagtccga ttctcttgtt tgatgagcca ctcgccaatc
    15181 tagatcccaa gtcaggtcag gatattatcg aattgattga ccagattcat aaggaagagg
    15241 ggacgacgac tctgattatc gagcaccgtt tggaggacgt tctgcatcgc cctgtggatc
    15301 ggattatctt gataaacgat ggtcgtatcc tttttaatgg gagccctgac cagttgcttg
    15361 cgactgattt attgactcaa aatggaattc gagaacccct ttatctaacg actctccgtc
    15421 aattaggtgt ggacttagtc aaggaagaac agttagcgaa tctggataac atgtctatct
    15481 caaaaggtca ggttcagctg cagaatgaac tggcaaaaga aactccagaa ttgcagtcac
    15541 tctttaaatt agaggacgtg tctttctctt atgatgatag accgatttta aaatccctac
    15601 atttagatat taaaaagggt gaaaagattg ctattgtcgg aaaaaatgga gcagggaaat
    15661 caactctagc caaggctata agtagcttta ttcagacgga aggacgctat ctttgggaaa
    15721 aacaggatat aaaaggcgat tctgttgcag agcgggcgga acgagtaggc tatgtgctac
    15781 aaaatcctaa tcaaatgatt tcaaccaata tgatttttga tgaggtggct ctagggctcc
    15841 gtttgcgagg tgtggatgag aaggaaattg aaacgagagt ctatgaaacc ttgaaaatct
    15901 gtggacttta tgaattccgt aattggccta tttctgccct gtcatttggt cagaaaaaac
    15961 gtgtcaccat tgcttcaatt ttggtcttag gagctgaaat tattctccta gatgaaccga
    16021 ctgcaggtca agatcagaag aactatactg agattatgga atttctcgaa gagttacatc
    16081 aaaaagggca taccattgtc atgattaccc atgatatgca attgatgctg gattattcag
    16141 accgggtcct tgtcatggtg gatggagaat tgattgccga tactgttcca gccagtctgt
    16201 tgagcgatcc tgagctgtta gtaaaagcca atctaaaaga aacctccatc tttaacttgg
    16261 ctaagaaact agatgtggat ccactggatt taacggcatt ttacaaagaa aggagagagg
    16321 gatgcaagct aaattaatcg gttaccagca tagagatact gtgattcatc gcttgtcagg
    16381 agctgggaaa cttctctttt tcattctggt atcattggcg gccatgatta gctatgatac
    16441 cagaatgctc ttgctgattg ccatcttttc agtctttctc ctctatttat cagaaattcg
    16501 ctttaaagat gtttcctttg tagccgtttt tgcgacggta tttgccgttt taaacgtttt
    16561 gatggtctat ctcttttctc ccgagtatgg ggttggactt tatggagaga gaagtgtgat
    16621 ttggcaggga atcggtgtct acactctaac cagccaggag ctcttttatc tgctaaattt
    16681 ggccattaag tatctttgca ccattcctct ggctattatc tttttgatga caacccatcc
    16741 tagtcagttt gcttccagtt taaatcaaat tggtgtgccc tataagattg cttattctgt
    16801 cagcctgacc ttgcgctata ttccagattt gcaggaagaa ttctttacta tcaagatgtc
    16861 tcaggaggcg cgtgggatgg aattatccaa gaaagcttct cttatgcaac gaatcaaagg
    16921 caatctgctc attattacgc ccttgatttt tagctcgcta gaacgcattg ataccattgc
    16981 gactgccatg gagcttcgcc gctttgggaa agagaaaaaa cgcacatggt atagttatca
    17041 ggccttgaaa aaaggagact atattacctt gctcttggca accttgtttt tagtagttag
    17101 tttactactt atcttgcaga atcagggacg attttacaac ccttggaaat agcttgaaaa
    17161 aattgaaaaa atcaagtcat ttctattgac aatgattctg aaagtgttat actaagaaag
    17221 tagtttcgct gatttacttc aaacctgttg tgaggtaagt taacgatgcc ttaaccacgc
    17281 tgtttgctga gcttgactcc gggcagtgtg gctatttttt tgcaatggtg aaaggaagca
    17341 agtcatgaca aatcacattg tattatttga acctcaaatt ccacaaaata cgggcaatat
    17401 cgcgcgtact tgcgctgcga ccaattctcc cctccacatc atcaagccta tgggctttcc
    17461 tattgatgac cgcaagatga agcgggctgg attggattac tgggataagc tagagattta
    17521 tttttacgag agtttggaag atttcatatc tcagatgaag ggaaaactct atctgatttc
    17581 gaaattcgcg gaaaaagtct attctgaggt ggatttatcg actgacgagg accattattt
    17641 tctctttgga cgtgaagaca agggcttacc tgaagatttt atgcgagaac atcctgagaa
    17701 ggctctccgt attcccatga atgatgaaca tgtccgcagt ctcaatgtgt ctaataccgt
    17761 ctgcatgatt gtctatgagg ctcttcgcca gcagaacttt gcaggtcttg agctcgtcca
    17821 tacctatgaa gtggataaat tgaaataaaa aatgaaaatg aacaaaatgc ttgcgcttgc
    17881 aagcgttttt tgttatgata aaagagtctt cagggcaggg tgtgattccc gaccggcggt
    17941 gactttaact aggaaatgat cttttccttt tatactttgt tgacaagctt tgcctaacca
    18001 gaagttatgc ctacagcttg tcgcctagtc taaaagaaaa atctctattt ccttctcttt
    18061 aaagaagtcc gcgagcgcaa gctgatgtgg tgagattcca caaccgacag tatagtctgg
    18121 atgggagaag acgaaagaat agctttgtct gttttgatag atttatagcc ggattgtaac
    18181 cacttgcttt gtttttcttt aatagagtaa gagggaactt ttgggatata aaaagtgaga
    18241 atagatagag gaatcctttc caacttcttc tgattttata gaaaattgga ggaacctgtt
    18301 atgacaaaca cacgtcgact ttcgaccatt gcaattttat cagccatctc atttgtgctg
    18361 atgtactttg actttccgct tttaccagcg gcatctttcc tcaagatcga atttagtatc
    18421 ttgccagtcc ttgtgggtct ggtggtcatg gatttgcctg ctgctctagg agtgctcttg
    18481 cttcgctcac tattgaaatt gcttcttaac agccaaggag tgaatactta cattggtttg
    18541 ccgatgaata tcgtagcttt gggagttttt gtcatcgtat ttgctttgat ttggaaaaag
    18601 gaacggacaa cccttcgttt cctactaggc tctctagctg gaactgttgg tttaaccttg
    18661 gccatgttgg ttctcaacta tgtttatgct gttcctttgt acgctaagtt tgctaacttt
    18721 gatattggaa aaattttggg actttccaac tacctaatga ccatggtatt accttttaac
    18781 ttgattgagg gtgtaatctt ttccgtttca ttctggttgt tgtacgtcct tttgaaacca
    18841 accttaaaac actatgaaag ataaacaaac atttttaatg aagggcagtt ttgccctttt
    18901 acttttcgtt attcttggct atatggtcaa attttaccct gaaatgttgg tcaattttga
    18961 ccaatcgatt cagactgcca ttcgaggaga cttaccagat tatttgacta ttctttttcg
    19021 atccctcaca cgtctgattg atatcccagt gattatcact tgggttgtca ttacagcttt
    19081 tgtcttttat cgtaagcgat ggaagataga aagtttcttc atgctgggaa atctggcttt
    19141 ggcaggtctt ttaatcgtga cctttaaaaa tatctaccag cgcccacgac cagctatctt
    19201 acatctggtg gaggagaagg gattttcctt cccaagtggg cattctctgg ctgtaacctt
    19261 gatggtaggt actttgattg ttattcttag tcagcggatt aaagagccag tctggagaaa
    19321 aatcgtacaa atcgtccttg gcctctacct agtcagtgtg ctggtatcaa gagtctatct
    19381 gggagttcat tacccatcag acgtccttgc cagtctctgt gtgggcttgg gagtcctgtt
    19441 tatcgagttt cccttctatg acaagctccg cttccaatgg cgatttaaag gcaaacagaa
    19501 gtgagtatcg aattcccttg aggagaaaga aatgaaagtc aatatagcag atcttcatcc
    19561 gactcaacta tatttatcag aaaagaagtt gcaagatatt cagatgcttt accagtcggc
    19621 agaaacaatc caagtcgatc caatcagtat tcttgccttt ggagattgtt tgctgattac
    19681 agatgggcat cacagggctt atcaggcttt attggcaggt cgggatacga tttctgctga
    19741 gtgggataga gatggtggtg atgaactata tcatctctat gcgcaagctt gcgaggaaag
    19801 aaagatttac tctgtttttg atttagaaga tcgtatccta gctcaagatg ggtatgaagc
    19861 aaaatggtat aactggtgtg atggttttaa tcaagcagca actcttttgt tgaaaaggta
    19921 gtgcattgtg ttttgttcct tattataagg tcaattattg tgaggaagct tttgcttggt
    19981 atcaggatgt gaacttggtt tacctcgtag atggggtgaa gcttccttac agtcaagcga
    20041 ccttggaagc catgtattcc tatttggatc ggcatggtga gcttttttgg attgaagtca
    20101 aggagaaggg agaatggttt ccaattgggg atattacact atctcaggat aatctcccca
    20161 ttgtgattgg gaattccgct taccaacatc gaggacttgg aaaaaagatt ctaagtgctt
    20221 tgattgaatt ggctcgagta aaaggatgga aagaattgag agtcaaggaa atctacacct
    20281 acaatcatgc ttctaggagg tgtttcaagt cgcttggatt tgtggaaaat ggagcaacag
    20341 aaaaaggaag gagttttata ttggaattag tctaatcctg ccactttctc ccccttaacc
    20401 tttgactatt ccgcaaaatt atcgtaaaat aaagagtaaa tgataaaatg aggtcagagt
    20461 ctgttcgctc tggcgatagt agtataaatg aggagaaacg ctttggaatt agaagtattt
    20521 gctgggcaag aaaaaagtga actatctatg attgaggtag cgcgtgctat cttggaactt
    20581 cgtggtcgcg atcatgagat gcattttagc gatcttgtaa acgaaattca aaactacctt
    20641 ggaacatcaa acagcgatat ccgcgaagct ttacctttgt tctacacaga gttgaacttt
    20701 gacggtagct tcatctcact tggggacaac aaatggggtc ttcgttcatg gtatggtgtg
    20761 gacgaaatcg acgaagaaat catcgctctt gaagaaaatg acgacgatga agtagcacca
    20821 aaagctaaga aaaaacgtgt caatgccttt atggatggtg attcagatgc cattgactac
    20881 aatgcagatg atccagaaga cgaagatgca tacgaagcag atccagctct ttcatacgat
    20941 gatgaaaatc cagatgatga aaaaaatgaa gtggaagctt atgatgcaga aatcaacgaa
    21001 atcgctccag atgacttggg agaagatgtg gatctcaacg aagacgacga cgagttttca
    21061 gatgacgacg ctgaaaccag cgaggaataa gagttagcta ttgacaatta tcctattttt
    21121 aggtatcata ttgtttgggc acctctttta gaggtcgggg ctccctagtt cttagggagc
    21181 tatttttatt ttttcaagaa gttatcttct tgtattttat actcaatgaa aatcaaagag
    21241 caagctagga aactagccgt aggctgctca aaacactgtt ttgaggttgt agataagact
    21301 gacaaagtca ggaacacata tctacggcaa ggcgacgttg acgcggtttg aagagatttt
    21361 cgaagagtat tagttgtgaa tctggtgcag ttgtcccaga ttattcttat tagtagggtc
    21421 ttgttttcta tatcccctcg tagttaacaa gaccttgagc attttagaaa gaggaatcta
    21481 tgtctacgaa atatattttt gtaactggtg gtgtggtatc gtctattggg aaagggattg
    21541 tggcagcgag tctaggccgt ctcttgaaaa atcgtggtct caaagtaacc attcaaaagt
    21601 ttgaccctta tatcaatatt gatccgggaa ccatgagtcc ttaccagcac ggggaagttt
    21661 ttgtgacaga tgacggagct gagacagatt tggacttggg tcactatgaa cgtttcatcg
    21721 atatcaatct caacaaatat tccaacgtga caactgggaa aatttatagt gaagttcttc
    21781 gtaaagaacg ccgtggagaa taccttgggg caactgttca agtcattcct catatcacag
    21841 atgctttgaa agaaaaaatc aagcgtgccg ctctaacgac cgactctgat gtcattatca
    21901 cagaggttgg tggaacagta ggagatatcg agtccttgcc attcctagag gctcttcgtc
    21961 agatgaaggc agatgtgggt gcggataatg tcatgtatat ccatacaacc ttgcttcctt
    22021 acctcaaggc tgctggtgaa atgaaaacca aaccaaccca acactctgtc aaagaattgc
    22081 gtggcttggg aatccaacca aatatgttgg ttattcgtac agaagagcca gctggtcaag
    22141 gaattaaaaa taaactggcc cagttctgtg atgtggcacc agaagccgtt atcgaatcgt
    22201 tggatgttga acacctttac caaattccac tgaacttgca ggcacaaggg atggaccaaa
    22261 ttgtttgtga tcatttgaaa ttagacgcac cagcagcgga tatgacagaa tggtcagcca
    22321 tggtggacaa ggtcatgaac ctcaagaaac aagttaagat ttcccttgtt ggtaagtatg
    22381 tggagttgca agatgcctat atctcagtgg tcgaagcctt gaaacactct ggctatgtca
    22441 atgatgtaga agttaaaatc aattgggtca atgccaatga tgtgacagca gagaatgtag
    22501 cagaactctt gtctgatgcg gacgggatca tcgtaccagg tggttttggt caacgtggaa
    22561 cagaagggaa aatccaagcc atccgctatg cgcgtgaaaa tgatgttcca atgttgggag
    22621 tctgcttggg aatgcagttg acatgtatcg agtttgctcg tcacgtttta ggtcttgaag
    22681 gtgccaattc tgcagagctt gcaccagaaa caaaataccc tatcattgat atcatgcgtg
    22741 atcagattga tattgaggat atgggtggaa cccttcgttt gggactttat ccgtctaagt
    22801 tgaaacgtgg ctctaaggct gctgctgctt atcacaatca agaagtggtg caacgccgtc
    22861 accgtcaccg ttatgagttt aataatgcct tccgtgagca gtttgaggca gcaggttttg
    22921 tcttttcagg agtttctcca gacaatcgtt tggtagaaat cgtggaaatt cctgaaaata
    22981 aattctttgt agcttgtcag tatcaccctg aactgtcaag ccgtccaaac cgaccagaag
    23041 aactctacac tgcctttgtt actgcagcgg ttgagaacag caattagcaa aatcagaacc
    23101 tttgagaaaa atctcagagg ttttttgcat acgatgatat tgcagtatat ctgaggtagg
    23161 ggtcctctgt atgtacctgc taccgttgaa atcaatagcg actccctctt gccctgtgct
    23221 agtgaatgga tttatcagta tattgaaatg aaataaaatt tgaacaaatt aattcggaaa
    23281 gccaaatcaa tttctagcaa agttttagga actggattgt at
//
LOCUS       DAVLGK010000035        21314 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLGK010000035 DAVLGK010000000
VERSION     DAVLGK010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21314
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.035"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            150..2303
                     /gene="blpA"
                     /locus_tag="VXE01_001528"
     CDS             150..2303
                     /gene="blpA"
                     /locus_tag="VXE01_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HEV0750411.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2314..3675
                     /locus_tag="VXE01_001529"
     CDS             2314..3675
                     /locus_tag="VXE01_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV0750412.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            3732..3887
                     /gene="blpC"
                     /locus_tag="VXE01_001530"
     CDS             3732..3887
                     /gene="blpC"
                     /locus_tag="VXE01_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV0750413.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FYQPIQL"
     gene            complement(3931..5271)
                     /locus_tag="VXE01_001531"
     CDS             complement(3931..5271)
                     /locus_tag="VXE01_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0750414.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGVSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(5285..6022)
                     /locus_tag="VXE01_001532"
     CDS             complement(5285..6022)
                     /locus_tag="VXE01_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0750415.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRFLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6027..6365)
                     /locus_tag="VXE01_001533"
     CDS             complement(6027..6365)
                     /locus_tag="VXE01_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0750416.1"
                     /translation="MKHMIIQTQKTVYKVNVDDVYYIQTHPTKAHTVKIVTEEASFNM
                     VQNLSNLENQYGETLMRCHRNCLVNLDKVKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            6642..6971
                     /locus_tag="VXE01_001534"
     CDS             6642..6971
                     /locus_tag="VXE01_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0750417.1"
                     /translation="MTDTDPIKRAQTLITDLNKAYQACKQATADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7139..8188)
                     /locus_tag="VXE01_001535"
     CDS             complement(7139..8188)
                     /locus_tag="VXE01_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0750418.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LGWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVEVVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8185..8916)
                     /locus_tag="VXE01_001536"
     CDS             complement(8185..8916)
                     /locus_tag="VXE01_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750419.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            8984..9394
                     /locus_tag="VXE01_001537"
     CDS             8984..9394
                     /locus_tag="VXE01_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0750420.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9404..9691
                     /locus_tag="VXE01_001538"
     CDS             9404..9691
                     /locus_tag="VXE01_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750421.1"
                     /translation="MKLSNLLLFAGAATGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(10058..11194)
                     /gene="dnaJ"
                     /locus_tag="VXE01_001539"
     CDS             complement(10058..11194)
                     /gene="dnaJ"
                     /locus_tag="VXE01_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0750422.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGGLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(11596..11952)
                     /locus_tag="VXE01_001540"
     CDS             complement(11596..11952)
                     /locus_tag="VXE01_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV0750423.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(11954..13777)
                     /gene="dnaK"
                     /locus_tag="VXE01_001541"
     CDS             complement(11954..13777)
                     /gene="dnaK"
                     /locus_tag="VXE01_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV0750424.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAESDKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14257..14781)
                     /gene="grpE"
                     /locus_tag="VXE01_001542"
     CDS             complement(14257..14781)
                     /gene="grpE"
                     /locus_tag="VXE01_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0750425.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(14808..15842)
                     /gene="hrcA"
                     /locus_tag="VXE01_001543"
     CDS             complement(14808..15842)
                     /gene="hrcA"
                     /locus_tag="VXE01_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV0750426.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16006..16515)
                     /locus_tag="VXE01_001544"
     CDS             complement(16006..16515)
                     /locus_tag="VXE01_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV0750427.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            17122..19455
                     /locus_tag="VXE01_001545"
     CDS             17122..19455
                     /locus_tag="VXE01_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0750428.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFNSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVGEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            19468..20931
                     /locus_tag="VXE01_001546"
     CDS             19468..20931
                     /locus_tag="VXE01_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0750429.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            20931..>21314
                     /locus_tag="VXE01_001547"
     CDS             20931..>21314
                     /locus_tag="VXE01_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0750430.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFVDGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTE"
BASE COUNT         6771 a         4334 c         3944 g         6265 t
ORIGIN      
        1 tttcaagcca cctctaaatg tttaaaaaaa ataatttcta atcacttttt taccattcag
       61 gaagttttaa tgactattca agatttcata aaatatgaac ttagttttat ggcataatat
      121 acctatccac tatatgaaag gaattgccaa tgacttctta taaacgtaca tttgttcctc
      181 aaatagatgc gagagactgt ggtgtcgctg ccttagcctc gattgctaaa ttctatggtt
      241 cagatttttc tctagctcac ttgagagaac ttgcaaagac caataaagaa gggacgactg
      301 ctcttggcat tgtaaaagcc gctgatgaaa tgggctttga aacaaggcct gttcaagcag
      361 ataaaactct ctttgacatg agtgatgtcc cctatccatt tatcgttcat gttaacaaag
      421 aaggaaaact ccaacattac tatgttgtct atcaaacaaa gaaagactat ctgattattg
      481 gtgatcctga cccttctgta aaaatcacta aaatgtcaaa agaacgcttt ttctctgaat
      541 ggactggagt agctattttt ctagctccca aacccagcta tcaaccccat aaagataaaa
      601 agaatggtct actaagcttc cttcctctga ttttcaaaca aaaatctctc attgcttaca
      661 ttgttctctc aagcttattg gtcactatta tcaatatcgg tggttcttat tatctccaag
      721 gaatcttgga tgaatacatc ccaaatcaga tgaaatcaac tttaggaatc atctcagttg
      781 gtctggttat cacctatatc ctccaacaag tcatgagctt ttccagagat tatctcctaa
      841 ccgttctgag ccagagatta agcattgatg tgattttatc ctatattcgc catatttttg
      901 aacttcccat gtctttcttt gcgacacgtc gtacaggaga aatcatttca cggttcacag
      961 atgctaactc tattatagat gccttggctt ctaccattct ttctcttttt ctggatgttt
     1021 ctattctgat tcttgtaggg ggcgtcttac tggcacaaaa ccctaatctc ttcctccttt
     1081 ctcttctttc cattcctata tacatgttca tcatcttttc ttttatgaaa cctttcgaaa
     1141 aaatgaacca tgatgtcatg caaagtaatt ctatggttag ctctgccatt atcgaagata
     1201 tcaacgggat tgaaactata aagtcgctca cgagtgaaga aaatcgctat caaaatatag
     1261 acagcgaatt tgtagattat ttggaaaaat cctttaagct cagtaaatat tctattttac
     1321 aaacgagttt aaagcaggga acaaaattag ttctgaatat ccttatccta tggtttggcg
     1381 ctcaattagt catgtcgagt aaaatttcta tcggtcagct gattaccttt aacacacttt
     1441 tttcttactt tacaactcct atggaaaata ttatcaacct ccaaaccaaa ctccaatctg
     1501 cgaaggtcgc taataaccgt ttgaacgaag tctatctagt cgaatctgaa tttcaagttc
     1561 aagaaaaccc tgttcattca cattttttga tgggcgatat tgaatttgat gacctttctt
     1621 ataagtatgg ttttggacga gataccttaa cagatattaa tctcacgatt aaacaaggag
     1681 ataaggttag cctagttgga gttagtggtt ctggtaaaac aactttagcc aaaatgattg
     1741 tcaatttctt tgaaccctac aaagggcata tttccatcaa ttatcaggat attaaaaaca
     1801 ttgataaaaa agtcttgcgc cgtcatatta attacctacc ccaacaagcc tatatcttta
     1861 atggctctat cttggaaaat ttaaccttgg gcggtaatca tatgattagc caagaagata
     1921 ttctaagagc ttgtgaatta gctgaaatcc gtcaagacat tgaaagaatg cctatgggct
     1981 atcaaactca gctctctgat ggagctggtc tatcaggagg acaaaagcaa cgaatcgctc
     2041 tcgctcgtgc tcttttaact aaagctcctg ttttaatact agatgaagct actagcggtc
     2101 ttgatgtctt gactgagaaa aaggttatag ataatcttat atccctaact gataaaacca
     2161 ttctctttgt agcccatcgt ctcagtatag ccgaacgaac taaccgtgtc attgttcttg
     2221 accaggggaa aatcattgaa gttggtagtc accaagagtt aatgcaggcg caaggcttct
     2281 accatcatct attcaataaa taaggagaat gtcatgaatc ctaatctttt tagaagtgtc
     2341 gagttttatc agagacgtta ccataactat gcgacagtgt tcattatacc tctttcatta
     2401 ctatttactt tcatcttgat tttctccctt gttgccacaa aagaaattac tgttacttcc
     2461 caaggagaaa tcgcccctac aagtgtcatt gcatctattc agtcgaccag tgataatcct
     2521 atccttgcta atcatttagt ggcaaatcaa gtagttgaga aaggtgactt actcatcaaa
     2581 tactctgaaa caatggaaga aagtcagaaa actgccttag caactcaatt acaaagactt
     2641 gagaagcaaa aagaaggact tggaatcttg aaacaaagct tagaaaaagc gactgatctt
     2701 ttttctagcg aggatgagtt tggctaccat aataccttta tgaattttac taaacaatcc
     2761 catgatattg aactgggtat ctcaaagact aacactgaag tttcaaatca agctaatctt
     2821 accaatagca gttcatcagc catcgaacaa gaaattacaa aagttcaaca acaaattgga
     2881 gaatatcaag agttgagaga tgctatcata aataacagag cacgcttacc aactggcaat
     2941 ccgcaccagt caattttaaa tcgttatctt atagcctctc aaggacaaac acaaggaacg
     3001 gcagaggagc catttttatc tcaaattaat caaagtattg caggtctgga atcatctatc
     3061 gcaagcctca aaattcagca agctggtatc ggaagtgtag caacttatga taatagttta
     3121 gcaaccaaaa ttgaagtact ccgcactcag tttttacaaa cagcctcaca gcaacaacta
     3181 accgtggaga atcaattaac agaattaaaa gtacaactag atcaagcgac acagcgctta
     3241 gaaaataata ccttaaccgc tccaagtaaa ggtatcgttc atctgaacag cgaatttgaa
     3301 ggtaaaaata gaattccaac tggtacagaa attgctcaaa tattccctgt catcacagat
     3361 acaagagaag tactaatcac ttactacgta tcatctgact atctcccctt actagataaa
     3421 ggacaaactg taagattaaa actggagaag attggaaatc acggcaccac catcatcggc
     3481 caacttcaga gtattgatca aactcctacc agaacagagc aaggcaatct ctttaaatta
     3541 accgctcttg caaaactatc taacgaggat agtaaactca tccaatatgg cttacaaggt
     3601 cgcgtcacta gtgtaactac aaagaaaaca tattttgatt atttcaaaga taaaatttta
     3661 acccattctg attaattttc agataacact ctataactat ttattatctt atcaaaaagg
     3721 agaatcataa catggataag aaacaaaacc taacttcatt tcaagaacta acaactaccg
     3781 aactcaacca aattataggt ggaggatggt gggaagattt cttatataga tttaatataa
     3841 ttgaacaaaa aaatacaaaa ggattttatc agccaataca actataaaaa aacaagacca
     3901 agagaacgca ctctcggtct tattttttct tcattctata tgtattacag taagtacctg
     3961 acgaaaaacg tgatcttggc aggtggtatt gagactggta ttgggatgac tttccacaat
     4021 tttcataacg gtatagagac caactcctct ctcctcccct ttagaacttg ctccaaagga
     4081 gaagatttca gaaatatcga ttccctcttc tttgatggaa ttttcaatga taaaggtctc
     4141 ctgtgctcca tttttaaaaa aggcaattga aacatgaggt tgacaggctt ctacactagc
     4201 ttcaatagcg ttgtcacaaa ggatagacac aacggttaga aaatcaagta gactcacccc
     4261 ctctacctga atctcctctg gaacttcgac attaaagaca atgttcttat ctctagcttt
     4321 tataaatttt ccagctagga gacttttgag ggcacgatcc cgaacattca ccaatcggcc
     4381 aaggtcatat ttattgtcct gcaatttttc actagaatcc tttaagaccg agtcgtagat
     4441 ctcttttatc tgctccatat cctcctcttc aatgcccaga cgtaagctag tcaagaggtt
     4501 ggtgtagtca tggcgaaaac tccgtacttc cttataaagc tcctctatat gccgactata
     4561 ccgctccatc tctctgtagc gcaagtcctg ctcttggttc agtctctcat ggagtttgtc
     4621 cttcaaatag gtatccaatt tcttgataat ccccataaaa aagagcaggt aaaagactag
     4681 gatgagatgg cgaacagtcg ttgattgaat cccctgttca tattcaaagt aagacagatt
     4741 ttgtatcacc aaatagtaag cccccattat ccagttaatc tgagtcaggg acttttgaaa
     4801 atctttatcg agaatcccct ttctcaagct agtgaaatca tagtccaacc atttcaaaaa
     4861 agctagagaa atgaagaaat tgaaaattat tatacataac caaataaatg agtagtcatc
     4921 atatacttgc ccttgtccca aaaatggaag cacaaaatag gaaacacctc tataaaagag
     4981 attcactaat atcattggaa agagaccata aaagagaagg agttttttag gaagttctct
     5041 taacaataag aaagataagc ctatgccgta caagggttcc ataaaataag ataggtaaac
     5101 atttcctacc atatagccaa gcattccaaa aacaacggcc aacagtatct taaaaagaaa
     5161 ggccttaaaa atcctctcaa aagtgagact aattccatct accttaaaga atatgacaat
     5221 ttttaatccg tgagtaacaa gtgtatacaa caatatccaa gcaacattca taaactctcc
     5281 tagctcagtg taagttatta atagcctcag acacttccct gaccttataa cgcgcgatta
     5341 gacaacttcc accattggga aagaaaagca gtttttcttt cttatctaaa tgcaccacat
     5401 tggcaggatt gatgagaaaa gagcgatggc actgcaagaa acgaggctcc tgcttgagaa
     5461 cctcctctag actcgctgta aattccagcc tgtctgtctt ggtatagaga ataacacgat
     5521 ggggtcttgt ggacgtttcg agatagtaaa cctctttaaa aggatactgg aattgagcaa
     5581 attttgattt aaagtaaaag caatcttccg ctagactttt actgtcttga ccattggcat
     5641 agaggagggc tgtctcgata cgagattcaa actcctctgc cgaaagggcc ttatcaatat
     5701 aatccagagc agacacttgg tagcgaaagg acaggggcat aaactccgag tgagtcgtca
     5761 caaagacaat cagggcatac ggatcccgat cccgaatctt tctagccact tccagaccct
     5821 tcatctcctc atttcgaatc tcaatatcca aaaagaatag ctgatgggcc cccttctcat
     5881 gcacctctgc cagcaattga tctggcttac caaaaacttc aaaagaactc agagtgatat
     5941 gatgttcctt caagagtttc tcaatcgtcg tttcaattct agtctgttgg gaaaaatcat
     6001 cttctaaaac aaatattctc atcttcttac tctccttctt tcaaccattt ttgacgaatt
     6061 tctctatagc gacgtctggc atacttgaca gcgtattgac cttcttctcc aagaaaaagg
     6121 attctttctt gaaaatcaat cgattttact ttatcaagat tgaccaaaca atttcgatga
     6181 catctcatca aggtttcccc atattggttc tcaagattac ttaaattttg aaccatatta
     6241 aaactagcct cttctgtaac aatctttaca gtatgggctt tagttggatg tgtttggata
     6301 tagtagacat cgtcgacgtt tactttatag actgttttct gtgtctgaat aatcatatgt
     6361 ttcattggat tctcctccta agaaaagaat aacagaaaaa atctaacaca agcacaccca
     6421 atcctaaaca gtctttgaaa gctcctaaaa gaattatttt tctacaatat catgatgagc
     6481 ttaccactat tttatcataa aattcactca gcgcaattca agacatttca atgacaatta
     6541 aagatttaaa ggcgaaaaag gagataaaag tgatagactg acagtatcaa aacacagttg
     6601 ctagaatcaa gactggcacc cagattagag gaggaattct catgacagat acagacccta
     6661 tcaaaagagc tcagactttg attactgact taaacaaagc ctatcaagca tgcaaacagg
     6721 caaccgctga cgacgtccgc tttcaggagc aattaaactc tattcttggt tttctagcca
     6781 aggctgaaac agtggataat cgattcttga ttgaattgga aaaattttac cagacttcca
     6841 gtcttctcat gggactcagc gctcttgatc cagatgctcc aactcgcgcc gcttggcggg
     6901 cctatgaccg cttccacttt gaccaagtca agaccaagtt aatactcaat gagaatcaaa
     6961 gagcaaacta ggaagctagc cgcaagctgt acttgagtac ggtaagacga cgctgacgtg
     7021 gtttgaagag attttcgaag agtataagtc tctacggacc aaccattatc ctgtagtaac
     7081 aaaaaagaag ttgagacaga ctgaactcaa cttctttttt agtgtcgtat cagcaatgtt
     7141 agtcctgcat ctgacgtttt acctgataag gcaaatacaa gactagtaaa accaaaccag
     7201 ctcctagtaa ggctagaagg gctagttttt cttggaaggt aatcaaccca acaactactt
     7261 ccacaagtaa aacaaaactg gtcaatcctc gaactacctc ctgtaagcct ttttcctttt
     7321 gccccttgtc cagcggaaag agttgggtca aatactggta gtcaaaggca tgatagaggg
     7381 ccagcaactg gaagagcaag aggtagttaa agagaactac cactgctgtc gcaatccaag
     7441 cttgctcgat aaaaacctgc gccagtacgg aaagtaagag aagacgaaga ctgagagcaa
     7501 agaggtcgcc atttcgcaga taagaacgca gatagagatt ttgccaaatc ttcccaggca
     7561 ccttctgaac agcctttaag ataaagtcca gataggcacg acgcttgaca ctgtttgaaa
     7621 ttcccttgac ctgcgtaaag agggcaaaga aacgaagcaa gacttgctta cgcttgcttt
     7681 cttgagaaat aagatagtcc cagcccagtc cagtttcagt gaaaaatttg ctggcctttt
     7741 gacgaaagtg gaaatatttt cctaccccca ataaaagcac atagagcaga aaaactggca
     7801 agccataacc cattgctaaa aacaagggcg caaataacag caagaaaagg gtctgtacaa
     7861 agagccaaaa gactagggaa atgccagttt gacgcttgag atggagcttg atttcctctt
     7921 ctccaactaa gagaaagagc ttgtctggag cctccatata ggtggcaatt cctccccaaa
     7981 gtaaaagtaa aacagacgta attcctacaa acaaaaggat aggccaatga ttttcaggaa
     8041 aatgttgtaa gagttgactg tactggtagg ctagaaagcc caacaggaca agcaggaaca
     8101 agacaaagtg gtcattgagc acatagcgca gataaccaag acactcctta cgaaaggcct
     8161 gctttctctt taaaaacaag tctttcatag atcctcctct ttggtcagag ccaagtaaat
     8221 atcattcaaa ctagcctcag gcatatcaaa ggcttcacgt agttgcagga gattgccttt
     8281 ggcacgcacc tctcccttgt gaagaatgac aaaggcatca cacatcttct ccgccgaatc
     8341 cagcacgtgg gtactcatga gaatagactt gcccttttgc ttctccactt ccaaaagctg
     8401 aatcaaatca gaaatagcca gcggatcaag accaaggaaa ggctcatcca cgatgaaaag
     8461 acttggatcc accacaaaag cacagataat catgaccttc tgcttcatcc cttttgaaaa
     8521 atgaacaggg aaccagtcta atttctgttc caaacggaac atttttaaca agggctctac
     8581 tcgttcgaaa gccacttttt gctcaatacc gtaagccata gcaaccgttt cgatatgctc
     8641 tctgagggtc aattcctcat acagactagg cgtctcagga atgtagccaa tctgcttgcg
     8701 gtagctagtc gcatctcctt gcagagtcag gccattgata ttgatggagc cactataagg
     8761 tgccaacaga ccgataatct cattgatcgt cgttgatttc ccagcaccat tgagaccaat
     8821 caaaccgacc aactgcccac tttcaacagt aaaggacaca tctttcaaaa caggaacatg
     8881 aacatagcca cctgtcaggt ttttaatttc taacatattt tctccaaatc tggtataatg
     8941 tagctatatt atatcaaaat tcagtacagt agaggtagat tttatgtcag attgcatttt
     9001 ttgtaaaatc atcgcagggg aaattcctgc ttcaaaagta tatgaagatg agcaggtcct
     9061 tgcctttctt gatatctctc aagtaacact aggacacacc ttggtcgtgc caaaagaaca
     9121 ctatcgcaat cttttggaga tgaatgctac gagcgccagc caactctttg cccaagtacc
     9181 aaaagtagct caaaaagtca tgaaagtcac taaggctgct ggtatgaata tcatttccaa
     9241 ctgtgaagaa gtcgctggtc aaacagtttt tcatactcac gttcaccttg tgcctcgcta
     9301 cagtgctgac gatgacctca agattgattt tatcgcccac gaaccagact ttgacaaact
     9361 tgctcaagtc gctgaaacca tcaaaaacgc ttaaggagtt gctatgaaat tatccaacct
     9421 actgctattt gcaggagctg caaccggaag ttatctggtt acaaaaaatc gccaaaccat
     9481 cacagatgaa gtcttgaata ccactgaccg cgttcaagct atcaaagacg atgtggatat
     9541 tatccaaaat agcctgcaaa tcatcgacca gcaaaaagaa cttatcaagg aataccaaga
     9601 agacttgact tacaagttta aggtcttgga aaaggatatc cagactagac tagctgtgat
     9661 aaaagaaatg cagggaactg aagataagta aaaagagccc cccggctctt ttttaaaacg
     9721 taaacaagtt atagtgaatt gaatttagaa tagcacatca tagtttctaa agcattgtta
     9781 gagattactt taaaatcctc ttatcaattt gttcatattc tatttcaatc tactatatat
     9841 atcccatcaa ctatgcatca taatttaggt aactcatact caataaaaat caaaaagcaa
     9901 actagaaagc taggcacaga ctgctcaaaa caccgtttta aggttgtgga tagaactgac
     9961 gaagtcagct caaaacactg ttttgaggtt gtagatacga ctcacatata tacgacaagg
    10021 caacgctgac gtggtttgaa gaaatttttg aagagtatca ttctccatca aaggcatctt
    10081 taatatggtc aaagaagcct tttttctttg gatttacttt caagccacca gcagccgcga
    10141 attctttcaa ggctactttt tggcggtcgt tcaagcctgt cggtgttacg acattaacag
    10201 taacgtattg gtcaccaact gcaccgccac gaaggctcgg tgccccctta ctacgtaggc
    10261 ggaatttctt accagtctga gttccctctg gaataaccaa ttcaacatca ccgtgaacag
    10321 ttggaatatc tactgtatca ccaagagccg cttggacaaa gttgaggttg agattgtaga
    10381 agatagtcgt tccttcacgt tcaaacttgt cactagcttc cacagaaact actacataca
    10441 agtcaccata aggtccaccg ttaaagcctg cttcaccttg accagcgagg cgaatttgtt
    10501 gacctgtttc cacaccagca gggattttca catgtacgct atgagcttgt ttctcatgac
    10561 ctgttccatg acaggttgta catggatatt tgatttcttt tcctcgaccg tgacagacat
    10621 cacaggttac ttggcgacgc atcataccaa gaggagtctg cgtatcgacg ttaatgacac
    10681 cagcgccatg acagcgtcca caagtgactg gacttgtccc tggcttagca ccagatccat
    10741 tacatgtacg acagccagct tcacgatgat acttaacttc cttctcagtt ccgaagatag
    10801 cttcttcaaa ggtcaaattg acacgatact ggagatcatc tccttggcga ggagcgtttg
    10861 gattgcgcga agaaccgcct ccgccgaaga aacttgagaa aatatcctca aaaccaccga
    10921 agccacctgc cccattgaaa ccgccgaaac caccagctcc accaaaacca ccattggcgc
    10981 ctgcagcacc atactggtca taggcagcac gtttttggtc gtcactcaaa gtctcatagg
    11041 cttcttgaac ttccttgtac ttgtcctcag caccaggctc cttgttgata tctgggtgat
    11101 attttttgga aagcttacga taagcctttt tgatttcgtc tgccgaagcg tttttggata
    11161 cccccagacg atcataaaat tcagtattgt tcataattca agatacaaag ggcgtcaaac
    11221 ggacacagcc atctaggagt tttgacgacg gacgcttacg tcctagaaaa aactatcttt
    11281 ttggcacagt ccgtagcccg tgttcagtta cgaacaccct tattcctttc tattgatgtt
    11341 ctgaatcgaa ccaccattta ggtcgggttc aattcctttc ttttatattt agtaagaaat
    11401 tctgaaaccc gtgttcagtt acgaacactc tttgttcctt tctattgatg agacaaaacc
    11461 caaacaaatg agattccgtc cctttttatc gaaaaacaga ggctgggttg caacctctgc
    11521 aaataagtaa attaacttta ttttgatttt aaatatccta taagtacaga aatatttata
    11581 tatttttgtc tcttcttagt atttgcctat ataattccaa ttgatcataa gaaatacaac
    11641 tactgtccaa atcataccaa ttatgaacgg tattacaaat ttatatgttt gtatttctaa
    11701 tgatatcata gctgatacca tcgccgatac aaatgcagac aacaatactg aggtaacaaa
    11761 attccttacc gcttcatcat ttttgacaca actatcatgc tcagctaata taatttctct
    11821 atatctagct aaatattcta ttggaatatt atcaataaaa tcttttgatg ttctatagtt
    11881 atcagcttga ttacaaaaat cattataaac ttttcgtgta ttttttagat actcttcatc
    11941 caatacactc atcttacttt tccgtaaact ctccgtctac gacgtcatcg cctgcgtttc
    12001 ctgttgcttg tgcgccttct gctccttctt gagcttgttg cgctgctgcg gcttgttcgt
    12061 agagtttaac agcaagtcct tgagcttttt cgttcaatgc ttcaagtttt gctttcatgt
    12121 cgtccaagtt gttgtcttct tgagctttct taaggtcatc aagggcagct tgggcagcgt
    12181 cacgttctgc gtcgaagcct ttaccttcag tttccttgat tgtcttttca gtcgcaaaga
    12241 ttgcttggtc cacttcatta cgaaggtcta cttcttcttt acgtttctta tcggattcag
    12301 cgtttgcttc tgcatctttc atcatgcggt cgatttcttc gtcagtcaaa cctgagttcg
    12361 attggatgac aatagtttgt tctttttgag ttccaaggtc tttggcctta acagacacga
    12421 taccgttctt gtcgatgtca aatgttactt cgatttgagg aattccacga ggtgcagctg
    12481 ggatatcagt caattggaag cgtccaagag tcttgttatc tgctgccatt gggcgttcac
    12541 cttgaagaac gtggatatca acggctggtt ggttgtctgc tgctgttgag aagacttgtg
    12601 atttagatgt tgggattgta gtgttgcgat cgataagttt tgtaaatact ccacccattg
    12661 tttcgatacc aagtgacaat ggcgttacat caagaaggac aacatccttg acatcaccag
    12721 taatcacacc accttggata gccgcaccca tagcaactac ttcatcaggg tttactgatt
    12781 tgtttggttc tttaccagtt tcagctttaa cagcttcaac aacggcaggg atacgagttg
    12841 aaccaccaac aaggataact tcgtcgattt ctgacaagct caaacctgca tctgaaaggg
    12901 cttgacgaac tggaactttt gtacgttcaa caaggtcacg agtcaaatca tcaaatttcg
    12961 cacgagttaa agtcatttcc aagtgaagag gtccagcctc acctgcagtg ataaatggca
    13021 agctgatttg tgttgaagtt acaccagaaa ggtctttctt cgctttttca gccgcatctt
    13081 tcaaacgttg cattgccatc ttgtcagtag acaagtcgat accgttttct ttcttgaatt
    13141 ctgctaccaa gtggtcaatg attttttggt caaagtcgtc accaccaagt ttgttgtccc
    13201 ctgcagttga caatacgtcg aagacaccgt cacccaattc aaggatagag acgtcgaatg
    13261 taccaccacc aaggtcaaat accaagattt tttcttcttt gtcagtcttg tccaaaccat
    13321 aagcaagagc tgctgcagtt ggttcgttaa caatacgttc tacttcaaga ccagcaattt
    13381 taccagcgtc ttttgttgct tgacgttgag cgtcgttgaa gtaagccgga actgtaataa
    13441 cagctttggt tactttctca ccaaggtagt cttcagcgta gcctttcaag tattgaagga
    13501 tcatagctga gatttcttgt ggagtgtatt cttttccatt tgcagaaact ttttcagaag
    13561 ttcccatctt agatttgata gagataactg tatctgggtt tgtaactgct tgacgttttg
    13621 cagcatcacc aacgatgatt tctccgtttt tgaatgagac tacagatgga gttgtgcggt
    13681 ttccttctgg gtttgcgatg attttgcttt cagttccttc aagaactgca actgctgagt
    13741 ttgttgtacc taagtcaata ccgataattt tagacatgtg tttttctcct tgttagttaa
    13801 ttttctattt ttctttttga tactcttctt aagtggcgac gccgtcagag cttgactttg
    13861 tcaatctctt tgactaaact ttgagcctaa ggtctcaaaa tttgcgcaaa tagcgccaca
    13921 gcgaagagta tcgtctttgg ttcgcttcgc tcactattac aaagccaaac atattttatc
    13981 tttcttcata gtttattgtc gtttcggaca agttttctat tatgtaaatt gcgacacgaa
    14041 gagtcgaaat cgattttatt tcgacgacga gttagtaagg aagctagaca aacgccatag
    14101 cgactgccgt tttctgacga gttgctttag ctaccgtcag aattgccgaa tcgaacacgc
    14161 cctaagctct gagtaaaaaa gatagatttt cttgtgttca tcgaacactt cgtcaatctc
    14221 ctatttttac tgcgagcttt ttacgggctt tgtatcttag ttatacacca ctaccattgc
    14281 tgggcgtagg atgcggtcat ggagtttgta gcctttttga aagacttggg cgatggtatc
    14341 tactgggtgt tcatcgtctg ctgggagagt ttggatggcc atatggtagt tatggtcaaa
    14401 ttcgccatct gctgcgattt cttcaattcc ttcttctttc aaagcgtgaa tcaagctttc
    14461 ttgcaccatc cccaagccct tcttcacatc atctgtcaaa ccttcaactg caagtgcacg
    14521 ctcaaggttg tcaagagatg gtaagattgc ttttgccaag tcctggctac gataacgttg
    14581 caagttttga cgttcttcat tggcacggcg ttggatattt tgcatttctg catgagcgcg
    14641 aagatatttg ttttcgaact catctgcacg ttcatttgcc aagtccaact cagacttttc
    14701 aggagttgtt tcttcagctg tttccacaac ttcctcttct tgaacttctt ctacttcttc
    14761 attttttata tcttgggcca tgttcgcctc ctttaatgat ttcaatctta atgtacttca
    14821 taatgattac tgctgaggta gcggtaaaaa tctgtcaact tcatggtcaa aacacggttg
    14881 accacattga cttgattgat tagctgttgg taatccagat taactggacc gataatggct
    14941 agaattccaa ctccccgata aggaatgagg aacttactac taatcaccgc taggtcagct
    15001 aaacaggact cttgaccgtc tgcaacacga acattttgca tctgatcctc acgcaacccc
    15061 tcacgaatct ccaaggccac cttttgcggt tggtcaaaga actgataggc tgctagattg
    15121 gcaaaattca agagattgac cttgcccgcc atcacaatgt tttcgttgaa catttcctta
    15181 aagatgtgtt caaagagatc gatgacatta tccgttgttg taaagtaacg ctggataatc
    15241 tgcggaatct ccgtccgaat cttgtagtga atatctaaaa cggtgtgacc gaggaaacgt
    15301 tcctgaatga tgctcttcag tttcagcaaa tcctcctgca agaagttcct tggaatcaga
    15361 aactgactag taaccgttcg cgactcgtct agggtaaata ccgccaaggc tgtatgttgc
    15421 cccaaaacaa cgatatcaaa ggctgtcaaa cgttgcctgc tcggctcaac atccagtgcc
    15481 actaccgtac agccactcag gtctgttagc aagttagcag cctcttgcag aatatcctcc
    15541 aatttgaaga attcctgatc aaaggctttg acaatctcat atacctcatt ttcagccagc
    15601 cggtcaaaat ccagtgagtg tttcacatag tactgaaaac cagcaacact tggcatccga
    15661 ccgcttgaag tatgagcctt ctcaagcaac ccttgttttt ctagttccgc catgtcatta
    15721 cgaatggttg cactgctaga gttaatagac tcttgcaagg cttttgatcc gacaggttcg
    15781 tgcgttttgg taaagatgtc aataatcaga tttaaaatat cctgctgacg ctctgtaacc
    15841 atctcatcac tcctctctgt ctgatcaatt agcactcaat gcatccaagt gctaacttat
    15901 gattctatta tacaccctta gaagagaatg tcaagacaaa aactcaaaaa attagcactc
    15961 ttttatcaag agtgctaaaa atcaatctga agacctagaa ccttgctatt catctactcg
    16021 gtatttcctt tttagtctga aataaccatg aattagataa gaaatcagaa aagcatataa
    16081 aacaaaaata agaaagaaag acatagaaag atcctctcta aacaaactcg tacaaacaac
    16141 aagaccacct aagaaagtag ttgtacagga acgaagtcta gatcgcataa cttcccattt
    16201 gagcccctta ctcatataga cttgatcctc tggaagtaaa tcagaagacg atttacgaag
    16261 aatcgaacaa gaacctgctc ctatcaattc ccaacctcta tctctaaaat cttgcagttc
    16321 atgcttatat tttttaagaa atctagaatc atagatacgg tagatgacat cgtctggttg
    16381 acattggtca aaatagaaca aaccaaaacg actcgttcta tacctccaac ctttcaaatg
    16441 catctcatgt aaatattctt cttccttgtc caaatcaaca atagtgaaaa tccgaaattc
    16501 tactctgcta ttcattgtct taccccaaaa ttagaaaaca tgcctggcgt tatttattag
    16561 ataattcttt ccgcttttga ctcaatctcc aaaaaatata agaaatctga atcgcaaaaa
    16621 ctatcaataa aacccaatct attatgaaag tcaaaaacac ttcccaactg aaagaactac
    16681 ctccagtgac aaactttgag aaaaacggta gtagagctaa aaagagaagc aaaataggaa
    16741 gcatccgcat tgttaaaatc cttttggcat aaaaaaatct ttatttaaac gaaaatatta
    16801 tggcaaaatt tacgccagtt tttgaacggc tgatgtagat attttatact ttcaaaatgt
    16861 ttaaatgtga ttatttattt ttgaaaaata gctcaccagc ccgactgaaa gtgcttataa
    16921 atgataataa gtcgcctgcc gaaaacagcg aaaaatagcg gtgttatgcg gagataatct
    16981 gacgcgatgc gaaagtatat tgcatactta ttttcaacaa tttagcagag tatttttata
    17041 agtgtgatat aatagaagta taatttgttc tgatagttta ttttatggag aagtagattt
    17101 ttagaatgcg gagggttcaa tatggttgag tttataaagt ctaagaaaga aatgagtgag
    17161 gaggatatta aagcaaattt catcactcct gctattgtat ccaaaggatg gaaaaatggt
    17221 gagcatatcg cttacgaaga atacttcact gatggtcgaa ttgaggttag aggagataag
    17281 gctcgtcgta aagaaggaaa aaaatcagac tattcactgt attaccaatt tggaactcga
    17341 attgcaattg ttgaggcaaa ggataataaa cacagcgttc gagcaggatt acaacaagct
    17401 attgaatatg gagagatttt agatgttcca tttgtttatt cttcgaatgg tgatggcttt
    17461 attgaacacg accgtatcac gagagaagaa cgtgagctgg agttagacga attccctact
    17521 cgtgaagaat tattttctcg tatgacgaag gaaaaaggat tgacgtacga aattacagaa
    17581 gctatctcaa ctccatacta tacagacgcc ttctcaatga aaacgccacg ctattatcag
    17641 caaatagcta tcaaccgtac tattgaaaca gttgccagag gacaaaaacg agtaatgttt
    17701 gtgatggcaa caggaacggg gaaaacgttc atggcttttc aaattattca tcgccttcga
    17761 aaagctggtt tggctaaacg agttttattc ttagcggata gaaacatctt agtagaccaa
    17821 acgatggctg aagactttag gccattcgaa aaggtaatga cgaaaattac accaaaactt
    17881 ttgactgctc ctgaaaaatt aaattctttt gaaatttatc tagggcttta tcagcaacta
    17941 actggtgaag atggaactga aacacattat caaaaatttg acaaagactt ctttgattta
    18001 atcgtaattg atgaagcgca ccgtggttca gctaaggaaa acagtaactg gcgtaagata
    18061 attgattatt tcaattctgc gacacagatt gggatgaccg ctactcctaa agaaaccaag
    18121 aatgcttcca atacggaata ctttggtgag ccaatctata cttatagttt aaaacaggga
    18181 atcgaggatg gttttttggc tccatatcgt gttatgagag ttaatttaga tgtagatgtg
    18241 gatggttatc gtccagaaac tggaaaagtt gatgctaacg gacaattaat agaagatagg
    18301 tactacggca ggaaagattt tgataaaacc attgtcattg atgatagaac gcaaagagtt
    18361 gccaagtttg tttctgatta tatgaagcaa aacaatgcac gatttgataa aacaattgtt
    18421 ttttgtgttg atattgacca tgccgagcga atgcgtgctg cacttgtaaa agagaatcta
    18481 gacttagtcc aagaagacta tcgttatgtc atgcaagtaa ctggtgacaa cgctgaagga
    18541 aaagctcaac tggataactt tatggatgtc aattctaatt ttcccgctat tgtaacaacg
    18601 tctaaattat taacgacagg agttaatgct aaaacatgtc gtttgattgt tttagactct
    18661 aatatccaat ccatgactga atttaaacaa attattggtc gtggcacacg tctttatcct
    18721 caaaagggga aagaattttt tacgattatt gattttcgaa atgttaccaa tttgtttgct
    18781 gaccctgatt ttgatggtga tccagtgaag gtgctggaaa caggtgcgaa aacagtcagt
    18841 ggttctacgc ccggtttcgt aggtgaggaa ggtgacccag tagaaaaata tatcgttaca
    18901 gacaagcagg ttaccattct taattctact gttcaagtat tggatgaaaa cgggaaactg
    18961 attaccgaaa gcctgaccga ctacactcga aagaatatct taggtagcta cgccactttg
    19021 aacgatttta tcacagtttg gcatacggca gataaaaaga agcttatctt agacgaactt
    19081 tataaaaaag gagtttatct agatgctatt cgagagtcgg agggaatatc agaacaagaa
    19141 atcgatgatt ttgatttact cctaaaactt gcctatggtc aaaaagaatt aaccaaaacg
    19201 gaacgtatca ataaactcaa acaaagcgga tatttatata aatatagtga ggaagcgcgt
    19261 gctgttttgg aaattttact gaacaaatac atggataaag gtattggaga actcgaaagc
    19321 attgaaacat taaaacttcc agaatttcag atatatggtg gaaccttcaa aatcatcaat
    19381 acttattttg gagataaaaa acgatattta caagcaatta aagaattgga gcaagagcta
    19441 tttacagtag cttaatgaaa ggaaagtatg tcaattacat catttgtaaa aagaattcaa
    19501 gatatcactc gaaacgatgc tggtgttaat ggtgatgctc aacgtattga gcaaatgtct
    19561 tggttattat tcttaaaaat ttatgatagc cgtgaaatgg tttgggaatt agaagaagac
    19621 gagtatgagt caattatccc agaggaatta aaatggcgaa attgggctca tgctcaaaat
    19681 ggggaacggg tattgacagg cgatgaatta cttgattttg tcaataacaa gttattcaaa
    19741 gagttgaaag agcttgaaat aacttcaaat atgcctattc gaaaaacgat tgttaaatca
    19801 gcttttgaag atgcgaacaa ctatatgaaa aatggcgtct tgttacgcca agtcatcaat
    19861 gttattgatg aagttgattt caatagccct gaagatcgtc attcgtttaa tgatatttac
    19921 gaaaaaattc ttaaagatat tcaaaatgct gggaactcag gagaatttta tacgccacgt
    19981 gcagcgactg attttattgc cgaagttctt gacccaaaac ttggagaatc aatggcagac
    20041 cttgcttgcg gaacaggagg cttcttgact tcgactctga accgtttaag tagtcaacgt
    20101 aaaactagtg aagataccaa aaaatataat acagctgttt ttggtattga aaagaaagca
    20161 tttcctcatc ttttagcagt tacaaatctg tttcttcacg aaattgatga ccctaaaatt
    20221 gttcatggaa atactttgga gaaaaatgtt cgtgaatata cggatgatga aaaatttgac
    20281 attattatga tgaatccacc ttttggaggg tcagaattag aaacaataaa aaataacttt
    20341 ccagcagaat tacggagttc tgaaacagct gatttattta tggctgtcat tatgtatcgt
    20401 ttgaaagaaa atggtcgtgt tggagttatt ttacctgatg gttttctatt tggtgaaggt
    20461 gtaaaaactc gcttgaaaca aaaactggta gatgagttca acttacatac gattattagg
    20521 ttgcctcata gtgtctttgc accgtataca ggaatccata cgaacattct tttctttgat
    20581 aaaacaaaga aaacagaaga aacttggttt tatcgtttag atatgccaga tggttataaa
    20641 aatttctcga aaactaagcc gatgaagtca gaacacttca atcctgttcg tgactggtgg
    20701 gaaaatcgtg aagagattct ggaaggtaag ttctacaaat ctaaatcatt tacacctagt
    20761 gaattggctg agttgaatta taatttagac cagtgtggct ttccaaaaga ggaagaggaa
    20821 atcttaaatc cctttgagtt gattcagaat tatcaagcgg aaagagcaac tttaaatcat
    20881 aagattgata atgtattagc tgatattttg cagttgttgg aggacaaata atgacaccag
    20941 aacaacttaa agcaagtatt ctccaaagag cgatggaagg gaaattagtg ccgcaaaatc
    21001 ccaatgacga acctgcaagt gaattattaa agagaattaa agctgaaaaa gaaaaactta
    21061 tcagtgaagg aaaaatcaaa cgagataaaa aggaaactga gatatttcgt ggtgatgatg
    21121 ggaaacatta tgggaagttt gttgatggaa gtactcaaga aattgatgtt ccttatgata
    21181 ttcctgatac ttgggagtgg gtgaggtttt ctacattggt tgaaattgtc agaggtggct
    21241 ctccacgacc aatcaaagat tatcttactt ctgaagtaga tggaataaat tggataaaaa
    21301 taggtgatac tgaa
//
LOCUS       DAVLGK010000036        21127 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLGK010000036 DAVLGK010000000
VERSION     DAVLGK010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21127
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.036"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..312
                     /locus_tag="VXE01_001548"
     CDS             <1..312
                     /locus_tag="VXE01_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0750431.1"
                     /translation="LIAPMTYEETMTSDFFEAWFQKFLLPTLNTPSVIIMDNARFHRM
                     GKLELLCEEFGYKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCF
                     N"
     gene            278..658
                     /locus_tag="VXE01_001549"
     CDS             278..658
                     /locus_tag="VXE01_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0750432.1"
                     /translation="MRLFCLVLVSIDYINCLSETTDKNWHKSDRVFVTNTGKTVHSSI
                     LSKSLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSI
                     YTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(796..2100)
                     /gene="eno"
                     /locus_tag="VXE01_001550"
     CDS             complement(796..2100)
                     /gene="eno"
                     /locus_tag="VXE01_001550"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV0750433.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2264..2710
                     /locus_tag="VXE01_001551"
     CDS             2264..2710
                     /locus_tag="VXE01_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV0750434.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2707..3822)
                     /locus_tag="VXE01_001552"
     CDS             complement(2707..3822)
                     /locus_tag="VXE01_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV0750435.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3831..4160)
                     /locus_tag="VXE01_001553"
     CDS             complement(3831..4160)
                     /locus_tag="VXE01_001553"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV0750436.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4105..4476)
                     /locus_tag="VXE01_001554"
     CDS             complement(4105..4476)
                     /locus_tag="VXE01_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV0750437.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4535..5968)
                     /gene="glgA"
                     /locus_tag="VXE01_001555"
     CDS             complement(4535..5968)
                     /gene="glgA"
                     /locus_tag="VXE01_001555"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV0750438.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5965..7104)
                     /gene="glgD"
                     /locus_tag="VXE01_001556"
     CDS             complement(5965..7104)
                     /gene="glgD"
                     /locus_tag="VXE01_001556"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV0750439.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7094..8236)
                     /locus_tag="VXE01_001557"
     CDS             complement(7094..8236)
                     /locus_tag="VXE01_001557"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV0750440.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8226..10154)
                     /gene="glgB"
                     /locus_tag="VXE01_001558"
     CDS             complement(8226..10154)
                     /gene="glgB"
                     /locus_tag="VXE01_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV0750441.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            complement(10637..12061)
                     /locus_tag="VXE01_001559"
     CDS             complement(10637..12061)
                     /locus_tag="VXE01_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0750442.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(12605..14884)
                     /gene="pulA"
                     /locus_tag="VXE01_001560"
     CDS             complement(12605..14884)
                     /gene="pulA"
                     /locus_tag="VXE01_001560"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV0750443.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(14996..16954)
                     /gene="ligA"
                     /locus_tag="VXE01_001561"
     CDS             complement(14996..16954)
                     /gene="ligA"
                     /locus_tag="VXE01_001561"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV0750444.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(17047..18225)
                     /locus_tag="VXE01_001562"
     CDS             complement(17047..18225)
                     /locus_tag="VXE01_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0750445.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLQSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(18305..19145)
                     /locus_tag="VXE01_001563"
                     /pseudo
     CDS             complement(18305..19145)
                     /locus_tag="VXE01_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
     gene            complement(19148..21049)
                     /locus_tag="VXE01_001564"
     CDS             complement(19148..21049)
                     /locus_tag="VXE01_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0750446.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         6387 a         4644 c         3757 g         6339 t
ORIGIN      
        1 ttaatcgctc caatgactta cgaagagacg atgacgagcg acttttttga agcttggttt
       61 cagaaatttc tcttaccaac attaaacaca ccatcggtta ttattatgga taatgcaaga
      121 ttccatagaa tggggaagct agaactcttg tgtgaagagt ttgggtataa acttttacct
      181 cttcctccct actcacctga gtacaatcct attgagaaaa catgggctca tatcaaaaag
      241 cacctcaaaa aggtattacc aagttgcaat accttttatg aggctctttt gtcttgttct
      301 tgtttcaatt gactatataa attgtctaag cgaaacaacc gataagaatt ggcacaaaag
      361 cgaccgtgtt tttgttacca atacaggaaa aacagttcat agttctatct tgagcaagtc
      421 tctccagcga gcaaacgaac gccttaaaaa accaattccc aaacatctgt cccctcacat
      481 cttcagacac accactatta gcatcttatc agaaaataaa attcctttaa aaacaatcac
      541 ggacagggtt ggtcattccg actctgaagt cactacttcc atctacaccc acgtcacaaa
      601 gaacatgaaa gatgaagcaa tcaatgtact ggataaagtt atgaaaaaga ttttttaaaa
      661 agttttgccc cttttttgtc ctctaaatac aaaaatagcc cttcggataa aatccgaggg
      721 gctagaaacg ttgttaaatc aacggccgaa cttttgaatt tcatggttcg ggataaaata
      781 gttcactgaa ctattttatt ttttaaggtt gtagaatgat ttcaatccac gatattcagc
      841 tacttcacca agttggtctt cgatacgaag caattggttg tatttagcga tgcggtctgt
      901 acgtgaaagt gaaccagtct tgatttgtcc tgcgttagtt gcaactgcaa tatcagcgat
      961 tgttgaatct tcagtttcac ctgaacggtg tgatacaaca gcagtgtaac cagcttcttt
     1021 agccatttcg atagcttcaa aagtttcagt aagagtaccg atttggttaa ctttgataag
     1081 gattgagtta gcagcacctt cttggatacc acgtgcaagg tagtcagtgt ttgttacgaa
     1141 gaagtcgtca ccaacaagtt gtactttctt accaagacgt tcagtaagag ctttccaacc
     1201 atcccagtcg ttttcatcca taccatcttc aatagtgatg attgggtatt tgttaaccaa
     1261 ttcttcaagg tagtcgattt gttctgcaga tgtacgaaca gcagcacctt caccttcaaa
     1321 tttagtgtag tcgtaaactt tacgttcttt atcgtagaat tctgatgaag cacagtcaaa
     1381 tccaataaat acgtctttac ctggtacata tccagcagct tcaatcgcag caaggatagt
     1441 ttcaacacca tcttcagttc cttcgaaacg aggagcgaat ccaccttcgt cacctacggc
     1501 agtttccaaa ccacgtgatt taaggatttt cttaagagcg tggaagattt cagcaccgta
     1561 acgaagggct tctttaaatg ttggcgcacc aactggcaag atcatgaact cttggaaagc
     1621 gattggagcg tcagagtgag aaccaccgtt gatgatgttc atcattggag ttggaagaac
     1681 tttagtgttg aatccaccaa ggtagctgta aagtgggatt tcaaggtagt cagcagcagc
     1741 acgagctaca gcgatagaca caccgaggat tgcattcgca cccaatttac ctttgttagg
     1801 agtaccgtca agtgcgatca tagcacggtc aatagcttgt tgatcacgta catcgtagcc
     1861 aatgatagct tcagcaatga tgttgtttac gttgtcaaca gctttttgtg taccaagacc
     1921 accgtaacga gatttgtcac cgtcgcgaag ttcaactgct tcgtgttcac cagtagaagc
     1981 tcctgatgga accataccac gtccgaaagc acctgattca gtgtaaactt ctacttcaag
     2041 tgttgggtta ccgcgtgagt ctaggacttc gcgagcgtaa acatcagtaa taattgacat
     2101 tttttactct ccttatgagt taaatttttt acacctctat aataccttaa aacccctcct
     2161 ttttcaagaa aaaacgttat ctttgtgcaa cttttcctta actttataaa gtaatcgctt
     2221 tcttttgtct gttttattct aacttttatg atatactgtt ttcatgacag atttatcaaa
     2281 acaattactt gaaaaagctc atggtgggtt aaaaataaat ccggatgagc aaagacgcta
     2341 tcttggtact tttgaggaaa gagttcttgg atatgtagat attgacacag caaatagccc
     2401 tcagttagaa aaaggctttt tatttatttt agaaaacctt caggaaaaag cagagccact
     2461 atttgtgaag atttcaccaa ctatcgaatt tgataagcaa gttttctact taaaagaagc
     2521 aaaagaaact gatagtcaag ccaccatagt atctgaagag catattactt ctccttttgg
     2581 cctggttatt catagtaatg caccagttca agtagaagaa aaagaccttc gacttgcttt
     2641 tccaaaactt tgggaagtta aaaaggaaga accagccaaa acatccttat ggaagaaatg
     2701 gtttagctaa atcttgcaca tatttaataa gtgcccaata ttggcagccg tgcgctccag
     2761 atagagactg gcatttttca aactatcttc taaaggttca cttttctcca aaatagaaaa
     2821 gacagcttgg atattttcaa atggtagggg aggtaaatct tcagcaagac taccgcaaat
     2881 agcaataaca ggaactccaa caggggttct ttttgcaaca cctataggcg ctttcccagc
     2941 aaagctttga ctatcaagtc ttccttctcc aacaacaacc aagtcagcat ctgaaacttt
     3001 cttatcaaag ttgattaagt ccaagcaggt atcaattcca gacacgatac ttgcctgagc
     3061 aaaggcacac aaaccaccag caaggcctcc acctgctcct gctcctttaa tttctaatgt
     3121 tgcaggtgag aatttttcat aaaaatcttg gatcgcctga tctacgactg caaacatagt
     3181 cggatgtaga cctttttgat tgccaaaagt gtaagtcgca ccttgatgac cacataaggg
     3241 actcacgaca tctgctaaaa tatgaatttg aacaccttca ggaattttat agcaattttc
     3301 tgttgaaaca gaagctaagt ttaataagga ttgaccggaa gcaggcaaga catttccatc
     3361 cctatcataa aattgataac ctaaaccagc agcaatcccc agtcctccat cattactggc
     3421 cgtgccacca acaccgatat aaatatcttt aatcccttta gaaatgagat ggagaatcaa
     3481 ctctccaata ccacaagttt ggatttgaag tggatttcgt ttctctagcg gaatttttcc
     3541 aagaccaacc aagtcagcta cttcaaatag tgccagttcc cctttttgaa aatagcgcat
     3601 ggcttctttt tgtccaaaag ggtctgtcac ttggatccat ttttctttta ggtcaagaga
     3661 atgtcggata gcatctacag taccttctcc cccatcacca acagggcaga ggagacattc
     3721 tacatctgct atcgattgtt ggaagcctct ttttattgct tcagctacct gttgagctgt
     3781 caagctttcc ttaaacgaat ccggtgcaat tacaatcttc atattttccc tcattctaaa
     3841 cagtcaatca aaggaagaac ttctaaaaaa tccctcttgt caacatgatg tggtatttct
     3901 tttttgagca tttctttgga acaaaaggcg attcctaact ccgccgactt caacattaat
     3961 agattattga ccccatcacc gattgccacc gttctttctt tagaaagttt tagtttcttt
     4021 ctccattttt ccagagtttc ttttttgacc tggggactta taatttgtcc aactaatttt
     4081 cctgttaaaa gaccttcttt gacttcaagc tggttggcag tgaaataggc aataccaagg
     4141 gattttgcta atctctccaa ctattggtgt aaatccacca gacaccagac caactaggat
     4201 gccattcttt tggagaatag agatgaactc tgggacattt agcgatagat gaattgagtt
     4261 gaagacgtta tcaaagacca aaataggaag accttccaac aaggacactc tttttcttaa
     4321 actgctttca aagaccaact ctcctcgcat tgctcgactt gtaatctgcg aaatttccgc
     4381 ctcatgacct gcctctctcc ctaaaagatc aatcacttct tctaggatta aggttccatc
     4441 tacatccaaa acacacaagc cttttacttg agacatcagt tctcctctct aaacagccta
     4501 aaaatcgtat gaagtcatca tacgatttta tctattaatt aactaaacta tggtacaagt
     4561 caaggtatga cttgcaggct gtatcccatg agaagtcact ctccatagct tgtttttgta
     4621 ggtttctcca aatgtctgga tggtttctat acaagtccaa tgctgtttgg aaagtccaat
     4681 ttaaccaata aggagataga ttgtcaaagc taaagccagt accgcttcct tcgattggat
     4741 tgaaagcgcg aactgtatct cgcaagcctc caacttcatg gaccaatggc aaggttccat
     4801 aacgcatagc catcatttga gacaagccac acggttcaaa acgacttggc atgaggaaga
     4861 ggtcacaagc agcgtagatt tcctgagcaa gtttgacatc aaaagtgata tttgttgata
     4921 gcttgtctgg gtaaatctga gcaaaccatg agaaagctcc ttcaaaggct ggatcgccag
     4981 ttcccaaaag aacaatctga acatcttctt gcaagatatg gtgaagactt tcgaccacca
     5041 catcaaaacc tttttgacgt gtcaaacgag aaacaattcc caccagtgga acgtctgctc
     5101 taacaggcaa gccaactctt tcttgcaatt ttgccttatt tttggctttc ccagacaaat
     5161 cttcctgatt gaaatgatag tctaaaagag catccgtctg aggattataa agatcagcat
     5221 caatcccatt cacgatacca gatactttac cagactccat tttaagaatc tgatccaaat
     5281 tacatccaaa ctgactagtc ataatttcat gagcatagct aggtgaaacg gttgaaacac
     5341 ggttcgcata gagaatacct gccttcatcc agttcagaca gttgttccat cgaagggtgc
     5401 catcagcgta acgttcaaag ccaactccaa acaaatcacc caacattcct tctgaaaatt
     5461 gtccttggaa ttctaaatta tgaatggtta aaactgtttc aatgtcctca taggcttgaa
     5521 tccaacggta tttttccttc aacaagaaag gaatcatagc tgtatggtag tcatgaacat
     5581 ggagaagatc aggaataaag tcaatccttt ccatagcctc aatggcagcc agttggaaaa
     5641 aggcaaagcg ttctccgtca tcaaaatcac cgtaaacatg accacggaag aaataatatt
     5701 gattgtcaat aaagtagaag gttacaccat ttaatactgt tttcttaatt ccacaatact
     5761 gtctgcgcca accaacgctc acctcaaaat gaagtacatc ttcaatctga tttccaaatt
     5821 tagcctctac catatcatag tagggtaaaa tcactgcaac ttcgtgccca gcttttacca
     5881 gtgattttgg aagagcgcca atgacgtctc ccaaaccacc tgtttttgaa aagggtgcac
     5941 cctctgctgc tacaaataaa attttcatga atgaatatcc tctgttactt tagcaccttt
     6001 cttaaccaca actggatgtt ctgcagttcc tcgaatcaca acaccaggct caacttcaac
     6061 ccctttgtcc aagatagcat attcgacctg agccccttct ccaataacaa cacgagggaa
     6121 gagcaggcta tctttaacca agctatcctt atggacatga atattacgtg atagaacaga
     6181 attagctact tgaccttcaa taatactacc agaggcaaac tgagaagtgc ttaccttaga
     6241 tgtattagca tagtaagttg gctcttcgtt tttgaccttt gtataaatct tttggtttgg
     6301 tgagaaaaga gaatagaatt tttgtgattc aagcatatcg atattcgctt gataataaga
     6361 tttaacagag tgaatattgg ctagatagcc cgtgtactcg taggcgaaag ctccctcttt
     6421 tacagccaaa tcccgtaaaa catagcgcaa tttctttgga tgttcttttt tagcttcttc
     6481 ttccaagtgt tcaatcaacc aaggtgtatc aacgacaaag atatctgtag acatattgaa
     6541 cgtttcagct gttgacttgc tatcaaagag tttatgagaa agaacatggt ctgtttcatc
     6601 tacatccaag attgcattta cttctgaaat atctttctta gctagttttt tataaactac
     6661 agtgataggc tcttttgttg tactatgtag gtggaaaact tggttcaaat caatgttaat
     6721 aagaacatcg cagttgaggg caaccgtttg gtttgagcca gaacgtttca aataagtaag
     6781 aagctgttgg tagtattctt ttccaactgt actactttct acacgggtat tgtaaattcc
     6841 tagatagtaa tgactaagaa gggttgataa gccccactcg cgtcctgaac gaatatggtc
     6901 aaatactgag ctgatattat cctgctggaa aataccaaag acactacgaa cacctgcatt
     6961 agcaaggctt gaaagtggga agtcaatcaa acgatatttc ccaccaaatg gcaaacttgc
     7021 tactggacgg tggtccgtca atgtcgacat attgtgaaaa ccaactgtat ttcctaaaat
     7081 ggcagaatat ttatcaatct tcatctgttg ctacccccac tacttcatta tatcctacaa
     7141 cttgtacttc atctgttcca tcaatttcga caccgtcaga aataatcgca ccttcaccaa
     7201 taatggcacg tttaatctta gctccttgac caatgatagc tccactcatg ataactgaat
     7261 caaggacttc cgctccttcg cgaacttgcg cgcctgttga aaggatagaa tgtttaacag
     7321 ttccatcaac gaaacatccg tctacaacta atgagtcttc cacatgagca tttgccccga
     7381 ggaagtttgg tggtgaaatc aagtttcttg agtaaatctt ccattgacgg ttacgactat
     7441 ccaaggcatt ttctggagaa atatactcca tgttcgcttc ccaaagtgac tcaatagtac
     7501 caacatcttt ccaataacca ctaaattcgt aagcataaac actttcacct gactcaaggt
     7561 aatttggaat gacattttta ccaaagtctg acatgccaac cttgctcttt tcagcagcga
     7621 ctaacatatt acgaaggcgt tgccaatcaa aaatgtagat tcccatagaa gcttttgtag
     7681 atttaggttg agctggtttt tcttcaaatt caacaatacg attgttagca tctgtgttca
     7741 tgataccaaa acggcttgct tctttaagag ggacgtctaa aactgctact gtcaagctgg
     7801 cattattatc cttatgagac tggagcatat catcatagtc cattttgtag atgtgatccc
     7861 cagacaaaat caagacatac tcaggattga cactgtcgat atagtcgata ttttggtaaa
     7921 tagcgtgact agtcccctca aaccaacgat ttccttcact tgcagaataa ggttgaagaa
     7981 tagagacacc tgaattaata ccgtctagtc cccagcttga accattccca atatggttgt
     8041 tgagagcaag tggttgatac tgtgtaacga ccccaacatt gtgaatccct gagttggcac
     8101 agtttgatag ggcaaagtca atgatacggt agcgcccacc aaattgcaca gctggttttg
     8161 cgatgctttg agtgagttta ccgagacgag ttccttgccc accagcaaga atcaaagcta
     8221 acatttcatt tttcattttc tactcctttt tggtttttat ttgtgacggt tttagtagat
     8281 ttcaagcgac gtttgatttt ccatacactt gctcccatag ccggtagggt aaaggttaag
     8341 gtctgctcat aatctttcca tagtccttct tgcgtttgaa cagtttgatt atgttctttc
     8401 caaacgcctc cccactcttc caactcagta ttccatactt cttcgtaaat tcctgcaacg
     8461 ggtagtccga ttgtaaaatc tttccgctca acaggtacca tgttaaagat acagactaac
     8521 atttctccct ttttaccctt acgaataaag gaaagaacac tctggtctcg attatccgca
     8581 tcaatgattt caataccatc atagctggta tcgatttccc acagacagcg atgatctttg
     8641 taaaactggt ttagctgaga agtgaaatac ttcatcttag cattcattgg gtcttctagg
     8701 ttagaccatt ccaactgttc ttcagatttc cattctagga attgaccgta ttcgctaccc
     8761 atgaagagca atttcttacc aggatgacaa atttggtacg tatagagatt gcgcaagcct
     8821 gcgaattgat tgtaacgatc tccccacatc ttatgcatca tactcttctt gccatgaacc
     8881 acttcatcgt gcgagaatgg caagagataa ttctccttga aaacatacat aaagctgaaa
     8941 gtcaccaggt taaagtcata tttacgatag atcggatctt cttcgtagaa acggaggata
     9001 tcattcatcc agcccatgtt ccatttgtag tcaaatccta gaccaccaat ctctttcatt
     9061 cccgtaatct tggtcgcaga cgaactttct tctgcaatca tcatcacatc tggatattct
     9121 aacttaataa cctcattcaa gcgttgaagg aaataataac cttcatagtt gagatttccg
     9181 ccatctttat taggtgtcca tggagcatca tcatagtcca aatagagcat gttgctaaca
     9241 gcatccacac gaataccatc caaatgatag acatcaatcc aatgcttaat gcaagaaatt
     9301 aagaaggact ggacttcatt ttttccaagg tcaaaattaa gggcacccca accatggtta
     9361 tgagccttat tatggtcttg gtattcaaaa gtcggtgtcc catcataata ggctaaggca
     9421 tcatcgttga tggtaaagtg acctggtacc cagtccacaa taaccccaat attatgggta
     9481 tgacactcct cgacaaaatc ttgaaactcc tctggtcggc cataagcatg ctctaaagcg
     9541 aagtaaccca taagctggta cccccaactc aaacctagtg ggtgggacat caagggcata
     9601 aactcaatat gagtatagtt catctcaact aggtaaggaa tgagttcatc tttcaattgg
     9661 gcaaaactat aaggactgcc atcaggattt ctcttccaag agccagcatg aacctcgtaa
     9721 atattgacag gacgttcagc aaagccccaa cgttttcttc gtgccagcca aagtccatcc
     9781 ctccatttct tatcaggaag ctctgttacg attgcccctg ttcctggacg agcctcatac
     9841 ctgacagcaa aagggtcaat cttcatcagt tgatgaccat tttgacgtgt gacatgatat
     9901 ttgtaaatat gcccttcttg agccatattg gtaaagactt cccagacccc aaagtcattt
     9961 cttaccattg gaatctgatt ttcaatccaa ttggtaaaat caccaaccaa gtgaacagcc
    10021 tgagcattag gtgcccaaac acggaaggta tagccatact ctccatttag ttcttcccta
    10081 tgtgctccta gataatgttg gagataaaaa ttttcacccg tcataaaggt ttttaatgct
    10141 tctctattat ccatatactc cctttctcct gtaagcgttt tctatgtttt tattatacta
    10201 cctttttaga gaagattcaa gtaaattact atacttcttt aattattttg aaaatctaca
    10261 acaagttcac ttactcgttc aattgtaaat caatattttt tcaaaaaatt gcgaaaacac
    10321 ctttcttttt ctactatagt gaaatgaaat aaaacatgcg caaatcgatt aaggaattta
    10381 atctaatttc taacaatgtc ttagaaatca aagtgtacta ttttaacttc aatgtactat
    10441 atatagtaaa atgaaataat aacaggacaa atcgatcagg acagtcaaat cgatttctag
    10501 caatgtttta gaagtagagc tgtactattc tagtttcaat atactataat accaaaaagt
    10561 tcgtattttt tctataatta ttattatttt atagcaaaaa aataaaacca ggaaaacaat
    10621 ttcctgattt tacacgttat ttcacatcaa aaacaatgga tttgacattt gtcatcgctt
    10681 caatgctata tttaattcct tgcactccag ctccagaacc tttgacacca aggaatggga
    10741 aattatctgg accacgctgg gttttattat taatgtggac tgtacctact tcaagttttt
    10801 cagcaatttc aaaggctttt ttgaaatcat ttgtaaagac tgatgattga aggccgaatt
    10861 cagattcgtt ggcaaaggca atagcttcct ctacactagc cacacgaatg attggtaaaa
    10921 caggaccaaa tggctcttcc catgccactt tcatatcttt tgtaacttgg tcaaaaagca
    10981 ctggccagag gagattgccc tcacgtttga ttggtgtaag agcctgagcc tctttttctt
    11041 gtgcatcctc aatcaagccc caaatgaagt cggctgaagc attgtcaata acaggtgtaa
    11101 tatcagcatt gtcaaatgga tcaccaactg ttaatttaga aacttcttcc tgaagcaaag
    11161 tagctaattt atctgctaca ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt
    11221 gtcctgagta gctaaaggct cccgcaacaa tttgcttggc agcatgttcc aaatctgcat
    11281 cttctagtac aagagctgca tctttcccac caagttccaa catgatagga cgcataccag
    11341 ctaaacgacc aatacgttct ccaataggag ttgaacctgt aaagttgatg aagttgactt
    11401 ctttgtgctc aatgatataa tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa
    11461 cacctgccgg aatccctgct tcttcaaatg ctttagccaa caagagtcca gaaatggaac
    11521 cttgtgttgg tggcttaaac atgacaacat tccctgcaat caaggcaggt gcaattttag
    11581 aagcagataa attaactgga taattaaaag gagcaatcgc tagcacgata ccaactggtt
    11641 cacgacggac aacagccagt ttgtttttac ttgctgcctc aaaaccacca ccttccattg
    11701 cttgtccagt gatacggaga ccttcctcag cagcataacg aatcaagtct gctgtacgca
    11761 ctacttctcc aattgctgct ttaatccctt ttgctacttc tttggcaagg atagtaccaa
    11821 ttttttcctt atcgcgttct aaaatagctg ctgttttatg caaataagcc gcacgttcaa
    11881 ttgctgataa agctcgccat gctggcaggg ctgcacgcgc agcttgcata gcctcatcag
    11941 cttcagtctg agtcatggct ggaactgtac ccaattcttc ttgattgatt ggtgaataaa
    12001 tcgtaatttc ttgttcggat gatttccatt ttccatttac taaattctga tatcttgtca
    12061 aattcttgtc ctcctgaaaa tgattaagat atattttacc aaattttcag aaaataacaa
    12121 ccctttttgc aaaatttttg agattatttt cacaagcttg atttttcaaa gtatactcaa
    12181 taaaaataaa aaaatccact acgtcaaggc gaggctaatg tggtttgaag aaattttcga
    12241 agagcgtgaa tgagtatcat ttatagtaaa ataaaaaaac tgaacaattt ggttggggac
    12301 agccaaacca atttctcaca atgttttaga aacaagggtg tgctattcca atttcagcct
    12361 actataactg tcatagattg ttgaaacaaa gtctaggtaa aagtcttcat aataaaaaga
    12421 cctcctatca aatgttcaaa aactttgata ggaggtcttg tttcgtgaaa atatttatca
    12481 aattttctat acaagtgagc tgttagccag gttctttcta ttctttcaat ttcaatgaat
    12541 ggatttttta tcaatactca taactgggaa tttgtctgtg taaaaatagc gagatagatg
    12601 gtatttataa aacactcaag acagctagac taatatcatt taaaacatta tcttcttttg
    12661 agcgactgtt ggttaccaac atagctaaat ttcctgcatt ttcaaattga tagggttctg
    12721 atttagcatt cacaactacc aagaggtgtt ctttgccgtg aacttcatag ataaggcagc
    12781 cgctatgttc aatcgcagaa tgcacaaaga catgatggta aatttcatca tagctagagt
    12841 aagaaaaggc accagttttt gtcttcaatc ggatgacttg acggataaac tcaatactgt
    12901 cttgacgctc attaatcaag ttccagttca cttggttcac actgtcagga gcattatagc
    12961 tattcatcgc acgctctcta tcatcatggg tcaactcacc attttcacca gtcgcaacca
    13021 gtttggtacg accaaattct tgaccgattt ccataaaggc catcccctgc atgagcagat
    13081 tcatggctgt ggcagtttcg accttgcgca tgatttgctc tgaactttgg tctggatgaa
    13141 gggttgccaa taaatcgtga agattgtaat tgtcatgggc ttctacatag ttaagcacct
    13201 gatttggatg tgtatagctt cctaattcac gacttcctag gattgcttta gctagaattg
    13261 gctctgtcgc agcaccactg acaaaacctg acttgatagc accataaact tctccccctt
    13321 tgacagcatc gcgctgattg tcattaaaga aaccaatatt tggcatctgg taggcattgt
    13381 ccttcttggc cttatcataa ggggcaagac ctgttcccat atcccatcct tctccataga
    13441 ggataatgtt ggagtcgatt tcatccaagc tttgacgaat catctgcatg gtcttgacat
    13501 catgaatccc catcaagtca aaacggaagc cgtcaatatt atattcctgc acccagtata
    13561 gaagagaatc aatcatatac ttgcgaaaca tttcgtgttc actggctgtt tcatttccaa
    13621 cacccgttcc attctggaag gtaccatctg gattcatacg ataatagtaa tcagggactg
    13681 ttgtttggaa tggtgcatca acaactgaga aggtatggtt atagactaca tccataatga
    13741 ctccaatacc cgcatcgtga taagcttgaa ccatcacctt caaatcacga atgacctgag
    13801 ctggatcatc tggattagtt gaaaaactag tttctggcgc gttatagttt tgtggatcat
    13861 aaccccagtt gtaggttaca tttccatcct catcgtattc tttatgacgg tctgcaattg
    13921 gttgcaattg aacataattg tagcccagct tcttgatgta atcaaaagca gttgactggc
    13981 cgtattggtt aactgttcca gcctgagcag cacccaagaa agttcctcga agatgttcat
    14041 ctacacccga tgtaggtgat ttagtcaaat cacgaatgtg catttcacag ataactgcct
    14101 tacatggatt ttccaagcgc caagtagcct ccgaaccgtg cttaacctcg aagttttcaa
    14161 cttgcttttc tacatggctc agaatagctg aacgtttgcc atcagggctg gtcgcgattg
    14221 tataaggatc acgtgtcagt gtttggtgat gagggaattg gacttgatac tgataagtct
    14281 tacctaccaa atcttcttca acatccaaac tccagacacc gattgtattg tccttatgat
    14341 tataagagta gctattgcct cttttcatct caaaagtctt ccaaacgggt gcatcattag
    14401 cagctgattc ataaacgaca acttgcactt ctgtcgctgt aggtgaccag agggaaaaat
    14461 gagcctgatt gtcctctaca cggcaaccta attctccttg gtaaccccaa tgatgatcaa
    14521 aactagcact gttaatggcc ttatcaaagg caaaaggatt ttgattttta tagaaaggac
    14581 tggcaatagc aggattttca gagtaataaa tcctatcatc gccttccaaa atccagacct
    14641 ctgttaatag gggatagtga ttaaaacgga tagaatattc tttactagtt tgacctgtat
    14701 gaaccacaaa attcaagctt tctataacat gtgaacttgg gtgttcaaag ctaaataaag
    14761 ctccaaaata atcttctttg taggttagca aatcaattcg ttgatcctga ctttttacaa
    14821 aggagcaagt gtcatattct ccattcttac gatggtaatg aatgcgcata gggtagttat
    14881 acatttttta tttttccttt ttactttgtt tctatttcac taataaattt ttgtcaatct
    14941 cgtctcaatt aacagacata gtcatattct ctaaactctg tttttaaacg atccattaca
    15001 aactttctag ccatgcctca tctctgacct ggataccaag ttcttgtgct ttttgcagtt
    15061 tacttccagc gtctgcacct accacgacga ggtcggtctt tttagaaaca ctacctgtca
    15121 ctttggcacc cagactttcg agtttacttt tagcttctga gcgcttgagt cgttccaatt
    15181 ttcctgtcaa taccacggtc aaacctgaca aggccgcatc cgctactacc gtctgtcctt
    15241 tatagtccag attgacccca gtttctttca attctctgag cagaatttca gagccttctg
    15301 tcgcaaaata agtctgaaga cttttggcaa tcacgccacc tagactttca atactagcca
    15361 cttcctctga atctgcctga tacagatttt caattgaatg gaaatattga agtaaaagct
    15421 gactagcctt gcttccgaca tgacgaattc ccaaaccaaa taagagcttc tcggcagaat
    15481 tttcctttga cgcttggata gcctgataca gtttagcagc ggacttttcc ttaaccccct
    15541 ctaaaaggag gaaatcctct tcttgcaaac gataaatatc cgccacatcc ttgactaaat
    15601 tagcagcaaa aagcttctca acaatagatg gaccaaggcc tgtaatattc atagcatcac
    15661 gagaagcaaa gtgaatcaag ccttccatga tttgagcagg gcaacgcgga ttgatacaac
    15721 gtagggccac ttcatcttca aagtgcaaca agtcagagtt acaacttgga cagtttgtag
    15781 ggatatctag tttttcttca gaaacccgtt tggactctac cacacgtaaa acggcaggga
    15841 tgatgtcacc agccttatat acaatgaccg tatcgtcttt tcggatatct ttttcagcaa
    15901 tataatctac attgtgcagg gtcgcacggc taacagtcgt accggcaagt tgtactggtg
    15961 ttagattagc agttggagtt acaacaccgg tacggccaac tgtccagtca actgataaga
    16021 gttgagcttc tttttcttca gcagggaact tgtaggctac tgcccacttt ggagccttaa
    16081 cggtaaaacc aagttcttct tgacttgcta ggtcgttgac cttgattacc actccatcaa
    16141 tatcgtaagg tagattttcc cgttcctgtc ctacttcttg gataaaattc cagatttcat
    16201 ctatgttttc agccaagatt cgcttaggat tgaccacaaa acctagttgt tctaggtact
    16261 tcaaaccctt ttcttggcta tcacgagttg aagggctggc ttcttgatag agaaacgttg
    16321 caagattacg cttggcaact actgctgtat ccaactgacg cagagttcct gctgccgcat
    16381 tacgaggatt agcaaattca ggctctccat tttcttggcg cgcttggtta acttggtcaa
    16441 aggaagcgcg tggcatgtaa cattccccac gaactgtgat atctagttct tctggcaaag
    16501 tcaaagggat gtccttaaca cgcttgaggt tttctgtgat attttcacca attgaaccat
    16561 ctccacgtgt taccccagca accaaaatcc ccttttcata agtcagcgag atagataagc
    16621 catcgatttt cagctcacaa atataggtcg gatgagccac ttccttacga acacgcgcat
    16681 caaaagcatc tagctcctca cgtgaaaaag catcctgcaa actataaaga ggatactgat
    16741 gactgtattt ttcaaaacca tctaaaacct tgccaccaac acgatgagtc ggactgtctg
    16801 ctagcacttg ctctggataa gcagtttcta actcgaccaa ctcacggtaa aggcggtcat
    16861 actcactgtc tgaaaccgag ggattatcgc tggtatagta ctcagtcgca tagcgattga
    16921 gcaaagcgac taactcattc attcttttat tcataagacc attttaccat aaaacaagcc
    16981 ctcctcacaa acgagaaggg cggaaaaaac acttagtttg aaattatttt tgaaactcaa
    17041 gcaaccttat atcaattttt caaaatgagt tcgaacataa ataaacgata tacaagacaa
    17101 gatgataaca ccacttccaa ttatcaggaa agaagagaga tgtacacttt gcaagactgt
    17161 cataaatcct tttgcaatag gcataaatag aatagctaag gtaaaaattg tactcagtac
    17221 tctcccaaga aattcgctct caaccttggt ttgtacttga gtaaaaaagt gaatattaaa
    17281 aatcgtcata aacaattcac aaactaaatt tccagaaaag gaaagaaaag ttggaagtgg
    17341 taatcccatc ataaaaactc caacacctgt caaagccagt aaaatcaaaa gattataaat
    17401 attagcttta attttactag ctagaagagc cccaatgatg gaaccaatag cccccatagt
    17461 taaaatactt gcataggctc cttctgaccc gtaaagctga ttcgaaaaag gaagtagaaa
    17521 ttcaaaagct gcaaaaaaga aattaacgct ggaagctacc agcaaaagga agaaaatttc
    17581 ttgctgatgc cagatatagt gtaacccatc cttgatatct acaaaaatat ctctcccagt
    17641 aaaagccttt ttctcttgaa cttttgcttc ctcttttgga aggaaagcca ctagaacaaa
    17701 agcaatgaaa aaagtcagcg agtctagcag tagcgtcata tggagacttg caaactgtaa
    17761 aacaaggaag gaaagaacag gagagctaac acctacaacc tgcaaaacca gctctaagcg
    17821 agaattatag atcacaatct catctttctc caccacttca gttatgatag ctttattggc
    17881 tgtgcgagaa aaggcaaaag caatagcctg cacaatgtta gcaacaatca aagcgccaat
    17941 catccagcta tcattcctta tgaaagaaat agccagacaa agaatcccac aaacaagatc
    18001 tgccgtcatt aaaatcttac gacgagaaaa acggtctgaa ataactccgc caaagggatt
    18061 gacgagaata gatgtgacga gctcagaaat ctgatacatt cctaaaactg tctgtcctat
    18121 agtccccata gaagccaacc agacactatt tccataatca tagagcatat ttcccatttt
    18181 attgatagcc ccacggctaa tcaactgcac tgcatagcga ttcatattaa agctcctctc
    18241 aaattttgaa actattgtat caaaaccgaa aggagctttt tattttttcc cttatttggg
    18301 aaaattaact tttgacaaat ttttcgtagt gttcctgata ataggctact tgctctggaa
    18361 gacctaacac atcaaaaata tgcatggcct cttgcatctg cttacagcct tctttacact
    18421 gtcctttttg atataaggca aaacctttta aataatggaa aacattacgc tcataaagct
    18481 taataccttt gtcaataatc ttctctgtat aagcctcaaa atagttggca ttataactgg
    18541 taacaattga gggccaaaat caacactaat ctcttatggc gactaatctc ttggtaaaat
    18601 tcctccctct ccataacttc tctaccaatc cgagtgacat agtctacatc gtagaaacta
    18661 tagaggttac cgaaaagaat caactcatac atggtccatt cttctgtttt gaagagataa
    18721 tctgctacct tatccaaatc atcctgcttc atatcataac tcgcatctct ttgacaaatc
    18781 agaccttgta gcaaaatcca gttcagctca aaataaaggg gagtcgtcga actcttagac
    18841 ttttcaagtt gttctctttg aagcttttga aaacctgcaa tatcgtttga atagtaaagt
    18901 gggataatct gtgccatcat agacacatgt tcatgattat gaaaattcct tgccttatcc
    18961 atgaaatttt cgattgttac atgaatgtta tccaaaatct caaagaaacg ggagactgcc
    19021 aggtcagact ccccaagctc aaagcgagat aactgagagg tagagcagga ttcgcctgct
    19081 gcttccttta aagaataatt tccacttgtt cgaaattcac gaaatacttt tccaagatgt
    19141 tccatcttta cacctgatct gataattctt cccactcaag catagcttct tcctgacgat
    19201 ggctgatttt gtccagctca gcctgtaatt ccatgagttt gtcggcatcg tttgtttcca
    19261 acatttgttc agaaatggct tggctttgac tttctagctc ttcaatttca gcttctagac
    19321 tttcgatttg tcgcatgagt ttgcgaactt ctttttgact ttctttctgg gcctgatagt
    19381 cattgactgg acttgcttcc tttgcttgat tgctagttga agcttcctca gtctgactca
    19441 tttctgctgt tgctttcttc tcaacatagt agtcgtaatc tccaaggtag agagttgaac
    19501 cattctcaga caattccaaa acatgagttg ccacacgatt gataaagtaa cgatcatgac
    19561 tgacaaaaag caaggtacca tcaaagtcaa tcaaagcatt ttccaacact tccttgctat
    19621 caatatccaa gtggttggtc ggctcgtcaa ggatcaggaa gttgttgttt tccatagaca
    19681 atttagctaa aagcaaacga gctttttcgc caccagatag catgccgact gattttttaa
    19741 catcatctcc tgagaaaagg aaggctccaa gacggttgcg gatttcaact tctggtgtca
    19801 gtttgaaatc attccagagt tcatccagca ccgtattact tggtgtcagc ttgctttggg
    19861 tttggtcata gtaaccaacc tcaacattag cgccaaagcg cttttcacct ttgataaaag
    19921 gaatctggtc cacaatagac ttgataaagg ttgacttgcc gataccattt ggaccaacga
    19981 tagcgacagc attcatctta cgaagatcta ggttgatagg ttgtgacaag acttccccgt
    20041 cataaccaat agcagtattt tcaacagtca aaacaacatt gcccgacgtt ttttcagact
    20101 ggaaggtcat gttggctgct ttcttgccag cttcaggctt gtccaaacgc tccatttttt
    20161 ctagttgttt acggcgagat tgagcacgtt tggtcgttga agcacgaact agattgcgat
    20221 tgacaaagtc ttccagagca gcgatttcct tctgttgctt ttcatagttt tttgcctcag
    20281 taactagctt ttgctccttc aattcgacaa aacgagagta attccccaca tagcgatcca
    20341 aggaatgctt ggtcaaatct agcgtaattg tcgcaacctt gtccaagaaa taacggtcgt
    20401 ggctgacgat aatgagggca ccgctatagt ttaccaagta attctctagc caggcgatgg
    20461 tttcaatatc caagtggtta gttggctcgt ccaagaccaa gagattgggc ttttcaagga
    20521 gcattttggc aagtgccaaa cgagtatttt gaccaccaga aagctcagca attttcatct
    20581 gccacataga ctcgtcaaac ttgaatccat tcaaaatcgc tcgaatatca gcttcatagg
    20641 taaagccacc tgcttggcga aaattctcag ataagcggtc ataatctgac atcagtttat
    20701 ccaaatcctc accagacttt tcacccatct ccagctccat ctgacgcagt tgtctctccg
    20761 tccgacgcaa atcattaaag acatgaagca tttcatcgta gatggtattt tcagactcaa
    20821 aacggctatc ttgggctagg taagacagag aaatatcttt tttcttattg atttctccgc
    20881 tagttggctc ctcttctcca actaaaatct tcaaaagagt agacttacct gcaccatttt
    20941 tcccaacaag ggcaatccga tctcgttcat caacctgcag gttgatatta tcgaaaagaa
    21001 cctctcctgc aaaagaacgt tcaattttat tagcttgtaa aataatcata agagtagtat
    21061 agcatgtttc cctaaggcat tcaagataat cgtaagtctt ttagtacaac ttttataaca
    21121 taaaata
//
LOCUS       DAVLGK010000037        20918 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLGK010000037 DAVLGK010000000
VERSION     DAVLGK010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20918
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.037"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(96..245)
                     /locus_tag="VXE01_001565"
                     /pseudo
     CDS             complement(96..245)
                     /locus_tag="VXE01_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(399..2021)
                     /gene="rlmD"
                     /locus_tag="VXE01_001566"
     CDS             complement(399..2021)
                     /gene="rlmD"
                     /locus_tag="VXE01_001566"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0750447.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDHVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIELREH
                     YNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2095..3069)
                     /locus_tag="VXE01_001567"
     CDS             complement(2095..3069)
                     /locus_tag="VXE01_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV0750448.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3143..3757)
                     /gene="pmp23"
                     /locus_tag="VXE01_001568"
     CDS             complement(3143..3757)
                     /gene="pmp23"
                     /locus_tag="VXE01_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV0750449.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3757..4731)
                     /locus_tag="VXE01_001569"
     CDS             complement(3757..4731)
                     /locus_tag="VXE01_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV0750450.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4739..5995)
                     /locus_tag="VXE01_001570"
     CDS             complement(4739..5995)
                     /locus_tag="VXE01_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV0750451.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6057..6488)
                     /locus_tag="VXE01_001571"
     CDS             complement(6057..6488)
                     /locus_tag="VXE01_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0750452.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6490..7092)
                     /locus_tag="VXE01_001572"
     CDS             complement(6490..7092)
                     /locus_tag="VXE01_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV0750453.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7076..7915)
                     /gene="prmC"
                     /locus_tag="VXE01_001573"
     CDS             complement(7076..7915)
                     /gene="prmC"
                     /locus_tag="VXE01_001573"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV0750454.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(7915..8994)
                     /gene="prfA"
                     /locus_tag="VXE01_001574"
     CDS             complement(7915..8994)
                     /gene="prfA"
                     /locus_tag="VXE01_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV0750455.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9004..9483)
                     /locus_tag="VXE01_001575"
     CDS             complement(9004..9483)
                     /locus_tag="VXE01_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0750456.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(9473..10072)
                     /locus_tag="VXE01_001576"
     CDS             complement(9473..10072)
                     /locus_tag="VXE01_001576"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV0750457.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            10195..10377
                     /locus_tag="VXE01_001577"
     CDS             10195..10377
                     /locus_tag="VXE01_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV0750458.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10513..11886
                     /gene="mnmE"
                     /locus_tag="VXE01_001578"
     CDS             10513..11886
                     /gene="mnmE"
                     /locus_tag="VXE01_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV0750459.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     SQVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDIEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11933..12868)
                     /gene="dapA"
                     /locus_tag="VXE01_001579"
     CDS             complement(11933..12868)
                     /gene="dapA"
                     /locus_tag="VXE01_001579"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV0750460.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12924..14000)
                     /locus_tag="VXE01_001580"
     CDS             complement(12924..14000)
                     /locus_tag="VXE01_001580"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV0750461.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14586..14658)
                     /locus_tag="VXE01_001581"
     tRNA            complement(14586..14658)
                     /locus_tag="VXE01_001581"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14623..14625),aa:Thr,seq:ggt)
     gene            complement(14758..15267)
                     /locus_tag="VXE01_001582"
     CDS             complement(14758..15267)
                     /locus_tag="VXE01_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV0750462.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15265..15361)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15390..15821
                     /locus_tag="VXE01_001583"
     CDS             15390..15821
                     /locus_tag="VXE01_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV0750463.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15903..16280
                     /gene="mscL"
                     /locus_tag="VXE01_001584"
     CDS             15903..16280
                     /gene="mscL"
                     /locus_tag="VXE01_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV0750464.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16322..17416)
                     /gene="hemH"
                     /locus_tag="VXE01_001585"
     CDS             complement(16322..17416)
                     /gene="hemH"
                     /locus_tag="VXE01_001585"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV0750465.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSKQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTIRINENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            17571..18794
                     /gene="pepT"
                     /locus_tag="VXE01_001586"
     CDS             17571..18794
                     /gene="pepT"
                     /locus_tag="VXE01_001586"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV0750466.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18830..19459)
                     /locus_tag="VXE01_001587"
     CDS             complement(18830..19459)
                     /locus_tag="VXE01_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750467.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            19424..19645
                     /locus_tag="VXE01_001588"
     CDS             19424..19645
                     /locus_tag="VXE01_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750468.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19722..20263)
                     /locus_tag="VXE01_001589"
                     /pseudo
     CDS             complement(19722..20263)
                     /locus_tag="VXE01_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521835.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(20367..20918)
                     /locus_tag="VXE01_001590"
                     /pseudo
     CDS             complement(20367..20918)
                     /locus_tag="VXE01_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6042 a         4386 c         3924 g         6566 t
ORIGIN      
        1 ctatttattt tttgagtttt aaactttggt agaagtcttg aactccttat atttacataa
       61 ctatttgcct ctataactat tatgacacga aaccaacaag caagttcaag cacctccata
      121 tctttattca aatgaggact aagatattca caaactttat cataaacctc tttatctttt
      181 ttcataaaag gggcatacaa cttagcaaat ttatcctaaa attttttgtt gcctttatca
      241 atcatttcaa cgctccttta aatataaaaa tgatcctatc aatctttatt ttgagcctat
      301 tttctaattg ataccttgca agaaaggaat aatagctgtt cctataccaa gtaggaatgt
      361 aataaatgca gaaagtcata tactgtcatt cttttctatt aaatcatttt gaagtgtctc
      421 aaagcatcca tgatggcttc ttctttttca ggtgtacact gtggaataat ttgtttatcc
      481 tttttagact tgttgtaatg ttctcgtaat tctattccac atttcttttt tatctgtgca
      541 atatataatg tcgaaacttt taattcaaat ttattccaaa catattcttt gatttgagca
      601 tatgttgctt tgctctccgc acttgtcaaa tccagctcaa tttcaacact tatgtgctta
      661 tcgacatcga gtttagacaa aagtgctacc gtctcgacgt gatgcgtttg aggaaataga
      721 tccaccggct ggactttctt caattcatat cccaattctt ggtagagttt gatatcacgc
      781 gccatggttg cgacattgca ggagatatag gcgatgcgat cggctcctgt ttgggcgctt
      841 gctttgataa agctttctgt caagcccttg cgtggaggat caaccaagat aacggttggt
      901 tgaatcccat ctttaagcca attcttcata gcattttcag ctgtgtcaca gacatagtgg
      961 gcgtttgaaa tattgttcag ctgagcattt tttttactat tctcaaccgc ttctggaatc
     1021 agttcaacac cgtagacttc tttgacatgc ttggcgactg ataaaccaat ggttccaata
     1081 ccagaatagg catcaataat cacgtgatct ttttttaact ctgcaaagtc aatggctgtt
     1141 tgatagagtt tctccgccat ttcagtattg acttggtaaa aggctgggcc agcgatttgg
     1201 aagtcatttc ccaacatctg gtccgtaata tagtcttgac cataaagagt gcgccactcc
     1261 ttaccaaaaa tcgcattggt attctggtcg ttgatatttt gcatgacaga cacaatctct
     1321 gggaactgct tgataacttg ttcaatcaat tggtcaacac gaaaaacttt tggacgagtt
     1381 gtcaccaaaa cgaccatgat ttgtcctgaa tagtgaccac gacgcaccac aagattccga
     1441 atcaatccag actgttcctt ttcgtcataa ggttttaaat caaaacgacg gagcaggtct
     1501 cgaagagcta ctacgacttg gtcaatgaca ggatcctgga taaagaaatc ttcaaggggc
     1561 atgaggttgt gcgaattctt acggaaaaat cctgtttcca agacaccatt cactcgacga
     1621 acgggcacct gcgccttatt gcgatacttg actggatgtt ccataccaag cgtttcagca
     1681 acttctacat ctgcaattcc agcaatcttg tagagactgt ccttgacttg cttggtttta
     1741 aacttgagct gttctggata agaaaggtgt cctaaatccg cgattcctga acgcaggtaa
     1801 gccaaatcta gatcttgatt acggtgtggt gactggacaa ggtatttttc aacttttcca
     1861 aagccaatct ttttattgac cttgaggaca cgcatgagaa ttttttcact cggtaaagca
     1921 ttctctacaa aaaagaccaa accatctacc ttggcaactc ctgccccttc atgggtcaaa
     1981 tcaacaattt caacttctac aatatcattt ttctttaaca ttcttttctc tttctattgg
     2041 ccgacaaaaa agacggcaac gttacggtta ccatccatta taccatgaaa tttcttaaga
     2101 accaaaactc ttgaagaagt tgacaagggc ttgccagagg gagcttaaga agttaccacc
     2161 gtcctctagc gccttatccg catcaaagtt aaggttgata tttttaaaac tgtcgccagc
     2221 ttgtgatacg atgctttgtt taaggtcatt tagggtttta gtgaaatctg cattgctgag
     2281 gatatcactc tttgagagat tcaaggcaaa attgatgatg atattgatct ggtttcctgt
     2341 tatgacctga tcaagtttgt aattttttaa ggtatcttca acaatcttgc ggatatcttc
     2401 ttctgtcaga tttcccttgc tttctttagc tttggcgagt cctgacttga tatcagctag
     2461 ggcaacgttt aatttattag catcatagcc tgatttgtcc ttgttttcag cattgatatc
     2521 tgacaaagcc tttagctctt cttgagccaa atctttattg gcttgcggca ccttggctcc
     2581 attagcttct agcgaatagt agatcccagc caaagcactc tcacctgtaa ctggaatggg
     2641 tgctgctaca gtgattttgg cgtgttccac acccaaagtt acggctgcat ttcggtacat
     2701 atcctgagtt accttagtga tgttttcagg tgtttcaatc ttgacctcaa gtggcgattt
     2761 gtcacctagc ttttgaatct tggctgatga atacaactgt aagctagagt cattggccac
     2821 attcatgatt ttagaataaa catcaggtgt catggtcttg agttctttgg tatctgttga
     2881 ggcattgtag cccagttttt taagagtttg atttttttgg tcttcagata gggaggaacc
     2941 taggacatat tcaggttgga cataggtttc atcgataact ttttgaacat ctgttgctgc
     3001 atggacgcta ttcatagctg ttactgccca caagaccgca gcactagtca gaaagagttt
     3061 ctttctcata gggaatttcc tcctttactt ctttatagta atatatctat cttaaagaaa
     3121 acttataaca aaaacacctg gtctagccag atgttgaaaa gagagtgaaa catttgatga
     3181 tgtaaaggtt aagtcgtacc tgtctagaat aataatagtt tcctccattt acatagagtt
     3241 cagcaccgtg aaaaatggaa atggggtgaa tataactata agtctttcca gtcgtattac
     3301 caagcaaggg ggcaacagtc tcacgagagt actgtttggc tagagccaag gtattttcct
     3361 tgccattttg ggcgataaaa tcgatatagg caggtccaaa attataggct tgaacagctg
     3421 tccagatatc tacacccttc ttctgcgcca gatagagatt gcctgtcaga gtttgaatgc
     3481 cttgccgaat gctagaggca ttatcattga tggtgttggt ggaaccactt gcagactcac
     3541 tagactgcat aacatctcct tcttttcctt ttgtttcagt ataaatcata gcaagcacaa
     3601 gctcttcgtt tgctggggtg tctttttcac tcaagatttc tcgcaccatg ggttgatagg
     3661 tcatgacttg tttgacatct tgatgaacgc ggtaagcttt atagccagca aaaaggaaga
     3721 ctgctagtac aagcactctt cgaattcgtt taaacattat ttactttgga tatcctcgat
     3781 atttttgatt aagatagagt aggttccatt ttcgttttgg ataaactcaa cagactcggc
     3841 gtcttgatag acgttattgg gaacgatgag ctcaattcca tttgataagg agagtttttg
     3901 gttttcaaat ttctttaatt ggcgactggc atcaatttca tcaaattgaa caggttctgg
     3961 tacggcttct ttgacttggt caataaagct caaacgagcc gtcagattgt tgtcaaaaag
     4021 gtcattagcc aatttctcag gtgacaattc attgctttct tctaggttgt tgaaaatcgc
     4081 tgatttgacc ttggattgaa attgaaaatc atctgtgtta aaagattcag caattctctg
     4141 ggctgttttt tccagttcct tgatagattt tttaggagaa atcttaggag cgacagcaag
     4201 aagattatct gaaaaatagt tcaaaaaagt cccgttgtac ttgattcgtt tttcaatcag
     4261 gtgatacttg ctactctgaa gattgaccac caaggcctca tcagctcctg ttccaaatcc
     4321 aggcaggtta ttctgagtta gcttgattgg attatcaact tctcctccga ggtgggtcaa
     4381 ggtctcccgc agggcaattc gcaagaaagc gaaatgttct acaccttctt tagaaaattg
     4441 aacaaaaatc aagtcattgg tcttgagatt ttcagaaatg ctaaactcct ctttccagag
     4501 attagccagc gttactgatg tctccaacaa atcgtctgta atatgattga agaagggatt
     4561 ttcttcttcg aaaatcccag tcttggcttc atctgaatac acatgttcaa tttttttacg
     4621 taggtattct tcgatttttg gagtaatatt gagaaactta tctgctaaga acagctcggt
     4681 atcatccgga ctgaactggt gaataatggc tttcttaata taaatgtcca taaaagtttt
     4741 attcctcgta taatgggaag gcatctgtca attctttgac tgcacttctc acttcttcta
     4801 atacagcctc attttctgaa ttcttaaggg ttttaatgat gagttcagcc actttgcgac
     4861 tttcttcttc accaaatcca cgtgcagtaa tagctgctgc tccgatacga atcccacttg
     4921 tcttgaatgg tgacaagctt tcgtaaggga ttgagttttt atttaaggta atattgactt
     4981 catccaacaa gttttgagca actttgccgt tttctacaac tttagtcaca tcaacaagga
     5041 agagatggtt ttcagttcca cctgaaataa tacggaaatc agggtcttgc aagaagacat
     5101 ctgccatagc cttgctgttc ttaattacat tggcagcata ttccttgaag gctggatcca
     5161 aaacttcttt gaaggaaact gccttagccg ccacaacatg ctctaaagga ccgccctgaa
     5221 tacctgggaa aatagctgaa ttgatttttt tagcaagttc ttcgtcattg gtcaaaatca
     5281 aaccaccacg aggtccacga agggttttgt gggtcgttgt tgttgtgata tgagcgtatg
     5341 gaactgggct tggatgaagg ccagccgcaa ccaaaccagc gatatgggcc atgtccacca
     5401 tgagcttcgc accgacagca tctgcgattt cacggaattt tgaaaaatcg ataatttgag
     5461 aataggctga agcaccagct acaatcagtt ttggttttac ttcttgggct tgtttcaaga
     5521 tagcatcaaa gtctaagagt tccgtttcag gatcaacact ataagaaaca aagttgtagg
     5581 tttgaccaga gaagctaaca ggagccccat gagtcaaatg accacctgat gccaaatcca
     5641 ttcccataac cgtatcacct ggctcaatca aggacatgta agccgcacag ttggcctgac
     5701 ttcctgaatg tggttggaca ttggcaaatt tagcaccgaa aatttctttt gcgcgttcaa
     5761 tagcaagagt ctctacaacg tctactacat cagttccacc ataataacgg cgtcctgggt
     5821 aaccctcggc atatttattt gtcaagatag acccttgagc tgccataaca gccttggaaa
     5881 ctacgttttc cgaagcaatt aactcgatat tattttgttg gcgttcttct tctttggcaa
     5941 tagcattcca gagatcagca tcatatgctt taaaatcatc tttgtcaaaa atcataggtc
     6001 ttctccttta ttgtgtgact agtccattag tttgatttta caataagaaa atcaaactaa
     6061 aagatgcgaa taaaccgttt ctgcatttta tcacaagtat agccaacttt ttcataaaat
     6121 gcatgagcac ccagacgatg attggcagaa tttaagcgga taaacccata accacatctt
     6181 ttggcttctt gttccaaccc ttgtagtaaa cttttaccga taccttgacc ttgcgcttga
     6241 ggtgaaactg ctaaagctaa gatattaaat cctgctttgg aatagagtga ttcgtaaact
     6301 tcagcgtgga catatccaag taagacatga ttagctgcat cctcatagcc aagtaggaaa
     6361 tgatgggaat cctgagacag tctagctagt tggctagccg tttcctctgg actaaaagta
     6421 taacccaaag cctcttggtt gatgtcacat atcgctttca catctgtttc ttgcaaatct
     6481 cttagcattt caagcctcct caaaagaaat ctctggcaac cgagcaagaa tatcttctcg
     6541 tttaattgcg ccttggcgta agattttcac cttgtctcca gacaaatcca caatagttga
     6601 atcctgtcca gttagaaaag catcgtcttc cagacccaga acctcttggt caaaatcctt
     6661 cagaatttgt tcaaaggtta caccacttgc ctgacctgag atattggcag acggcccaat
     6721 caagggacct gtctctcgaa ttaaatccag tgtgataggg tgactgggca tccgaaatcc
     6781 aatagttgca aggtcagaat ttacccaata gggaactcgg tcattggctt cgagaataat
     6841 ggtcaaggga cctggcaaaa aggtctctac aagtttttgt agataagctg gctgattctt
     6901 tgaaaagtgc aagatgtcct cgaaagaggc gatattgaga ttgagtgcct tatctctagg
     6961 acgacgtttg agttggtaaa catggtcaac tgctttttca tctaaggcct tggaaaaaag
     7021 accataaaca gtctctgtag gtagaacgac agctccacca ttttccaact cttgtctaat
     7081 cctgtccatc atcaaccaca accatcctat tttgaccaaa ttggtccttg agtgttcgaa
     7141 ctcttttttc aggaagatgt ttcctaaaaa gttcgggaac actttgacct tgcttgtatc
     7201 caatttcaag gtaaatctta ccaccatctt tgagatagtc ttttgcatct tccgcaattc
     7261 tacagtaaat agctaggcca tcctcgtctg caaagagagc tagatgaggc tccgaatgca
     7321 aaacattcaa gcctacctct gactcatctt cacgagagat atagggtgga ttggatacaa
     7381 ttatatcata tttttcagaa atttctgcaa aacaatcaga ttttttaaaa aatatattaa
     7441 gattttgatt gctagcattc tctgatgcaa gctctaaggc ctcttgagaa acatctgctg
     7501 ctgtcactga ccaatctggt ctattttttg ctagagcgag agcaatagct ccactacctg
     7561 ttccaatatc cagaactgag agattcgtct caagattttc agttagaata agctccacta
     7621 actcctctgt ttctggacga ggaatcaaaa cccgttcatc cacctttaaa tgcattccat
     7681 aaaaatctgc ctgtccaatg atgtactgag ctggcttgtg agctgctagt tgctggtaaa
     7741 tatcttctac aaattgtttt tcttcctctg ttgtcacctc ctgctggagg gcaaaaataa
     7801 agtctgtaaa agatagattt ttcagactac gatagacaaa agagaggctt tccgcttcct
     7861 ctccttgtct tatcaactct tcttcaaaat ttgaaaataa ttgagctaat ttcattattt
     7921 gtttaattct tctagttttt gtgtttggtc ataaagcacc aaggcatcca caacttcgtc
     7981 caatttacca gacaaaatcg tatctagttt ttggagggtc aagccgatac ggtggtctgt
     8041 gacacggttt tgtgggaagt tataagttcg gatccgttct gaacggtcac cagtaccgat
     8101 tgtcgactta cgctcagcgt cctgctcatc ttgagcaatc tgagcaaagt ggtcagcaac
     8161 acgggcacgg atgattttca tggccttctc acggttcttc tgctgggtac gttcttcctg
     8221 catctcaacc ttgatattgg ttggcaagtg aacgatacga acggcagtcg caaccttatt
     8281 gacgttctgt ccaccagcac cagaggcgtg atagatgtcg acacgaaggt cttttggatc
     8341 aatgtcgtat tcaacctctt caacttctgg cataacaaga actgtcgctg tcgaagtatg
     8401 aacacggcct tggctttctg tcacaggaac acgttgcaca cggtgggcac ctgattcata
     8461 cttaagctta gagtatacag actgacctga aaccatagca accacttctt taaaaccacc
     8521 gacaccattc atagaggctt ccatgacttc aaagcgccaa ccttgggctt ccgcatactt
     8581 ttggtacata gttagcaaat ctccagcgaa aagtgccgct tcgtctccac cagctgctcc
     8641 acggatttca aggatgatat tcttgtcatc gtttggatcc tttggaagga gcaaaatttt
     8701 cagtttttct tcatattctt ctttttcagc cttggcatct ttgagttctt gcttggccat
     8761 ttcttccaag tccgcatctc cgcctgattc cttaatcatc tcttcggcat cgacgatatt
     8821 ttgaaggact tgtttatact cacggtaggc tattacggtg tcacgattgg aagcttcttc
     8881 ttttgaaagc tccataaaac gcttggtgtc tgaaacgaca tcagggtcac tcagcaattc
     8941 tcctagttct tcataacggt cttctacagc ttgtagttga tcatagatgt tcattttttc
     9001 tccttatttc tcaattgtta aatcatagat tgctactact tcattctcgg atatttcccc
     9061 agtttcttta aatccataac tgagataaca aaatcttgcc tgttcatttt ctggttcata
     9121 agacaaccaa agtttattgc ttaaacctgc tggcgctgtt cgaacatagt ctagtacttt
     9181 atccataatt ggtttaaaat atccttgatt ttgaaaattc ttatcaatca taaaacgaaa
     9241 tagtaaataa tttccactac taattccgat ctttttatca taagctatca tcacaaaacc
     9301 tataattaca tcattatcat aaactgccaa tggagctaca aaatctccat ttttagtgta
     9361 gacgtatgct tcagctaaac taattgcgtt ggttgcaatg aattgttttt gatattcctt
     9421 gacatccaaa tttaaaacat caaaataatt ttccattgta acatctctta gttcaattgt
     9481 catagttttg ctccttgtta gaggttatca ttggcgcaaa ataatgttta cggcaaaccg
     9541 agatataggt ttcattacca ccaatctgga tctgttctcc atcgtaaacg ggcagtccat
     9601 cctgtgttcg caacaccatg gtcgcctttt tcttgcaata ctgacagatg gtcttgattt
     9661 cgtcaatctt gtctgctaaa agcaagagat atttggaacc ttcgaacaat tcattgcgaa
     9721 agtcattttt caagccaaaa gccatgacgg gtatgtctaa ctcgtccaca acacgagcta
     9781 ggtcataaac atggtggcgt ttgagaaact gggcttcatc gaccaaaaca cagtaaggtt
     9841 tttctggtag gtctcggata tagccaaaga tatccgttgt ttcctcaatc gcaagggcag
     9901 ggcgtttcat gccaattcga ctcgacacat agccaacacc gtcacgcgta tccagagccg
     9961 aggtcataat cacaacacct tttccttgct cctcgtagtt ataggccact ttgagaatct
    10021 caatcgtttt accagagttc atggtcccat aacgatagta caactgtgcc atgtttcttg
    10081 cttcacgtcc atttctaaat ttttgctaca ttctagtata tcataatttt cttaagcttt
    10141 aaacggcaaa atgtggtaaa atggaagaaa tcaaaactag tggaggaagc tattatgcca
    10201 tttgtacgca tcgatttatt tgaaggacgc acgctcgagc aaaagaaagc tcttgctaag
    10261 gaagtaacgg aagcagttgt ccgcaacact ggagcacctc aatctgctgt ccatgtcatc
    10321 atcaacgaca tgccagaagg aacttacttc ccacaagggg aaatgcgtac taaataagct
    10381 agcttaagca gaattgctta ggctttttca atctccaagt agcacccatt gaagaaatag
    10441 tctaaatttg ttacaatttg aaaagagact tggaaaattc caagaaaaga gcaattaatt
    10501 aaaggaaaca ttatgattac acgtgaattt gataccatcg ctgctatctc tactccacta
    10561 ggtgaaggag ctattggtat tgtccgcctg agcggaacag acagttttgc tattgcgcaa
    10621 aagattttta aaggaaaaga cttgagtcag gttgctagcc acactctcaa ctacggtcac
    10681 attattgatc ctctgactgg taaagtcatg gacgaggtta tggttggggc tatgaagtct
    10741 ccaaagacct tcactcgtga ggatattatc gagattaaca cccacggtgg tattgcggtg
    10801 accaatgaga ttctccagct agctatccgt gaaggagctc ggttggcaga acctggtgaa
    10861 tttaccaaac gtgccttttt aaacggtcgc gtagatttga cacaggccga ggcggtgatg
    10921 gatatcatcc gagccaagac agacaaggcc atgaacatcg cggtcaaaca acttgatggt
    10981 tccctttctg atcttatcaa taatatccgt caagaaatcc ttaacacact tgcccaagtt
    11041 gaggtcaata tcgactatcc tgagtatgac gatattgagg aagccactac tgctgttgtc
    11101 cgagagaaga caatggagtt tgagcaatta ctaaccaaac tccttaggac agcacgtcgt
    11161 ggtaaaatcc ttcgtgaagg aatttcaacg gctatcattg gacgtcccaa cgttgggaaa
    11221 tcaagccttc tcaacaacct cttgcgtgag gacaaggcta tcgtaacaga tatcgctggg
    11281 acaacacgag atgtcatcga agagtacgtc aacatcaatg gtgtacctct caaattgatt
    11341 gatacagccg gtattcgtga aacagatgac atagtggaac aaatcggtgt tgagcgttcg
    11401 aaaaaagccc tcaaggaagc cgacttggtt ctactagtgc taaatgccag tgaaccactg
    11461 actgcgcaag acagacaact tcttgaaatt agccaagata ccaatcgcat tattctactt
    11521 aataaaaccg acctgccaga aacgattgaa acttcgaaac tacctgaaga cgttatccgt
    11581 atttcagtcc ttaaaaacca aaacatcgac aagattgaag agcgaatcaa caacctcttc
    11641 tttgaaaatg ctggcttggt cgagcaagat gctacttact tgtcaaacgc ccgtcacatt
    11701 tccctgattg aaaaagcagt tgaaagccta caagccgtta atcaaggtct tgagctgggg
    11761 atgccagttg atttgcttca agttgacttg actcgtactt gggaaatcct cggagaaatc
    11821 actggggatg ctgctccaga tgaactcatc acccaactct ttagccaatt ctgtttagga
    11881 aaataagaaa aatccatgat ccttcattcg gtcatggatt ttattgtctt tattagtaat
    11941 ctggtcttaa gacccctgtt acagttgcct tagttgcttc gtagtcgcca tctacgacaa
    12001 ccttgataat gcgtttggca tcttcttctg gtgctggaac aagaggtaga cgagtgggtc
    12061 cagcttcaaa tcccatatag ttaagaattg ccttaactgg agcaggactt ggataagaga
    12121 agagagcatt aaccttagga atgaatttac gctgaattgc tgcggctttc ttcatatcgc
    12181 tttctgcaat ggcagtaaac atctcgtgca tttcatcccc atttgtatga gaggcaacag
    12241 aaataacccc atccgcccca aggttcatgg catggaaagc atctccatcc tcacctgtat
    12301 aaatcaagaa ctcttcaggc ttgtgctcaa tcaagtaagc catattagcc aagctagtac
    12361 attctttgac accgataata tttggatggt cagccaagcg aagcatggtt tctggagtca
    12421 attcgacaac tacacgccct ggaatgttat agataataat tggtaggtca gaagcatctg
    12481 caatagcctt aaagtgctga tacatccctt cttgagaagg tttgttgtag taaggaacaa
    12541 tagcaagccc agctgcgaaa ccaccaaatt ccgctacttc tttgacaaac tcaatagagt
    12601 cacgcgtatc attagtacct acacccgcaa tcaaaggaac gcgtccattg acaacctttt
    12661 gtacagccgc aaacaactcc aactcctcat cgtgggtcaa agttggactc tcagcagtcg
    12721 ttcctgcgag aagaattcca tccgtatgat gggccaataa atgctcaatc aaggctggaa
    12781 tagcatcaaa gttaatagaa ccatcctcat gaaagggggt aataaaggct gtaatgattt
    12841 tacattcttt taaatcttga taagacatga aaacacctct ctatttcaaa gaaggagttc
    12901 atctgaactc ctaaacgata tgactatttt aattcaaatt tcaattcagc tgttggacga
    12961 accaatccac gttcatgaag agtttcagca atctgaactg agttccaagc agcacctttg
    13021 agaaggttat ctgaaacaac ccacatgtga attccttttt ctgcatccaa gtctttacgg
    13081 atacgaccaa caaaggtatc acgtgaacca actgcattga tggcttgagg atagatttga
    13141 tgaactacat catcttcaag aacagcacct gggaaggatg cgatagctgc tttgacttct
    13201 tcaattggag ccacttcctt tgtttcaata taaactgact cagagtgagc tgacaagact
    13261 ggaatacgca cacatgtcgc agatactgca atgctatcat cttccataat tttcttagtt
    13321 tccttggtca tcttcatctc ttcgtacgtg taatcattat cagtgaagac atcaatttgt
    13381 ggaagagcgt taaaggcgat aggataatgt ttcttgtcac cacctgaagg caagatttcc
    13441 gcatgcaaat cacgtggttt cactccatca ttcaagacct cacgaagttc acgttgtgtc
    13501 tcaagaattg ctcccatacc agcacctgaa acggcttgat aagttgaaac aatgatacgg
    13561 tccaagcccc atttttggcg aaccggctca agagccacca tcatttggat tgttgaacag
    13621 ttagggcagg caatgattcc gttgtgggca tcaagtgcat gagcattgac ctctggaaca
    13681 accaaaggaa catctggatt ttgacggaaa taagatgtat tatccactac taccacgcca
    13741 gcttttactg cgtatggtgc atacttagct gatgtcgaac cacctgctga aaagagagca
    13801 atatcaactc cttcaaaagc tgtttcagtc gtttcttcaa tcgtaatatc ttgatcttta
    13861 aatttcaatg acttacctgc tgaacgtgca gaagcaaggt aacggatttt atcgattgga
    13921 agtgttgatt cttccaacat ttttatcatc tgagcaccga cagcacctgt cgcgccgact
    13981 acagcaactg tatatcccat aaataacctc tttcggaatt ttctaaaaat ttctataata
    14041 gaagtattat actacttttt ccatgaattg caaagctttt tcatcatttt ttggaaaata
    14101 aaaatcccca atcgctagac tagggattaa gaggcatctt catgtgatga gcaggttcac
    14161 acaactcatc aaggtccgct cctgcgttat gacctcctta tgctcaatag tagcccgaag
    14221 actacctatc gactcatcgc atctactatt ctactaaaga gaatgacttt tgtcaacaga
    14281 cgaaactctt tatactcttc gaaaatctct tcaaacttcg tcagcgtcgc cttgccgtat
    14341 gtatggttac tgacttcgtc agtttcatct acaacctcaa aaacatgttt tgagctgact
    14401 tcgtcagttc tatctacaac ctcaaagcag tgctttgagc aacctgcggc tagtttccta
    14461 gtttactctt tgattttcat tgagtattag ttttatttac acaggtgcat aagaaatata
    14521 ttggaaaaat tgggggcaga cataacaaaa acccttgtaa atcaagggct tttctgtcta
    14581 tttaatgcta attgccggga ttgaaccggc gacctcatcc ttaccatgga tgcgctctgc
    14641 caactgagct aaatcagctt acttaagaag tatactataa tcagaaaaac ttgtcaagtt
    14701 tccttagaaa ttttccatag gaaaaagcca ggtaagaact acctagctta tcttcttcta
    14761 tttacttaaa tcaattcgac gaccaatttt accaataata atcgctccaa taatcaatga
    14821 agcaaattca ccgattcctg ttgtaaacca agtaaggaag aatggtaatt ctgctacaat
    14881 atttaactct gcagcgatag taaacatgga aattgaaaag aggattgaaa agaagaaatg
    14941 atcttttcga atcaatccgt taaagaggta atccttgcta tattttgcaa aaagccaaac
    15001 acctaaactg aggaatacta aggttgaacc accaccaaca aagacatcta gcagtccgaa
    15061 gctaaagaaa ttagcaatca tacaaccgat ggtaactccg atgatgtact taggattgta
    15121 aaaagccata aagttcatca tttctgaaat acgaaactga taagcaccat agctgatggc
    15181 atttaggggc ggtgtgacag tcaaaacgac gtagatagca gcgacgattg caatatctgc
    15241 aacatcacga atagttaatt ttttcatctt ttctcctttg gcggttatcc gcgtgtaata
    15301 tgcttggtga aagaagctaa gcaccaaggg ttgattcatt caaccttact agtatagcac
    15361 aatagcctgc tttatgctat acttaaagca tgaaaaaacc tattcaaaaa ttttttaaca
    15421 atgaaatctt agcctatctc ttttttggcc ttgcgacaac tctagtttcg attctctcac
    15481 gactagtcat ttatcaacta agtcatcagg aactccttgc tacggccttg gcaaatatta
    15541 tcggtatctt atttgccttt atcacaaatg atacgattgt atttaagcaa aaaaagaaaa
    15601 atagacttat ccgtttagtg aaattttctc ttgctcgcct ttctactttt ctgttagact
    15661 tgtttttaac ttttctcttt gtaacccaat ttcctcacat catagggcaa ttcgtaactg
    15721 aaaacattga taagataaat gctattgaaa caataattgc acaaatattc attattatca
    15781 tcaattatat cttgagcaag gtctatattt ttagaaaata atgctccatt tatgagcctt
    15841 ttaattgcct tctataatga tttaggatac aatgaaacac gaaacattga aaggaaaaca
    15901 gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac cttgctgtcg
    15961 gtgttgtcat tgcctctgct tttggtgcta tcgttacttc acttgtaaac gacattatca
    16021 ctcctcttat tttaaatccc gctttgaaag ctgctaaagt tgaacgtatc gctcaacttt
    16081 cttggcatgg agtcggctat ggtaacttct taagtgctat tatcaatttt atctttgtgg
    16141 gtaccgccct cttctttatt atcaagggca ttgaaaaagc acagaaactg actggcataa
    16201 aggaagaaaa aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa gaaataaaag
    16261 ctctccttga gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa tccttttttc
    16321 tttactcttt gggtaacttg cctgcttttt caagcatttt tttgataaga taaggcatct
    16381 taacattctc ccgccctttt ttctcaatca gttttttcac aaattctggc atttgtaaat
    16441 cttcagattc agccaaaatg tttttcgtct cgtctgaagg aactaactca tcaaaggtct
    16501 cttcttctgg gagaaattcc ttaaactctt gattttcatt gattctaatt gtattgacca
    16561 aagcatcaat caaacgagaa tctgtatttg gcattggtgg acgatggtag tttaccccaa
    16621 attcctgaca taagtcataa cattccacat cgttgtcaaa caagacctca atatgctcac
    16681 tgatgaaact aataggtaca aaaatataat ggtctggatg ttctgtctgt tctctgagat
    16741 actccaaaac atctggttta atccatggaa taccaatatc actctcactc tgccaagtgt
    16801 tggtatattg ttttgaactc aagcccagtt tttcagcgac tagcttgcta ttttcgaaaa
    16861 tttggtctat ataaggatca ccaaagtcca aggcaaaaat aggcacacta tgggctgaaa
    16921 agatgacttt aaagctgtct tgctttactt cttcttttaa aatcttagca atttcatctg
    16981 cccaatagtt taagagcgct tcttcctgat accagtcctt aatgaccaaa aattgaattt
    17041 gtttgctttc taaaaatttt tcatagccca tgacagagta gaaagaataa tggggctcca
    17101 aaatcaagca aatacactgt tcaattccgt ctgcttccat ttgaccgatc acatctggaa
    17161 taaagggact ggaaaactta ttagcaaagt agacactgta ttcattcccc agcctagctt
    17221 ctaccaaggc aacctcttga cgggtaattt tttgcagagg cgtgcctcca attcgtacat
    17281 aattatcata gagagtctga atctcgtggt cttggggtct caccccacga cgaatatttg
    17341 tgaaaaaatc agctacacct tcaaaggtaa tctcttctgg tgaaccgaag gtcatcatta
    17401 aaattgcttt tttcatgact gcttccttgt gatgttttta tcaagtttat tttatcatta
    17461 attcatcgat aagtaaacgc taacataggg acattctcaa tcttctgtct tttgtttttc
    17521 tcttctttct atgatacaat ggaaaaaata aattcaaaag gagttttttt atgacttatc
    17581 caaatctctt ggaccgcttc ttaacctacg ttaaggtcaa cacgcgctct gatgaacact
    17641 ctactactac tccaagtaca cagagtcagg ttgacttcgc aacaaatgtc ctaattcctg
    17701 aaatgaaacg tgttggactg caaaatgttt actatctacc gaatggtttt gctattggaa
    17761 ccttgccagc caacgatccg tctttaacac gtaagattgg ttttatatcg cacatggata
    17821 ctgctgattt taatgctgaa ggagtcaatc cacaggtaat tgaaaactac gatggtggtg
    17881 tgattgaact agggaattct ggtttcaaac tcgatccagc tgacttcaag agtcttgaaa
    17941 aatatccagg acaaacgctc atcacaacag atggaacaac cttgctaggt gctgatgaca
    18001 agtcaggaat tgctgaaatt atgacagcca ttgaatatct aactgctcat cctgaaatta
    18061 agcactgtga gattcgtgtt ggttttggtc cagatgaaga aatcggtgtt ggtgccaata
    18121 aatttgatgc agaagatttt gatgtggatt ttgcctacac tgttgatggt ggtccactag
    18181 gtgaacttca gtacgagact ttctcagccg ctggtgctga attgcatttc caaggccgta
    18241 atgtccaccc tggtactgcc aaagggcaga tggtcaatgc ccttcagcta gcaattgatt
    18301 ttcataatca acttccagaa aatgaccgac ctgagttaac tgaaggttac caaggttttt
    18361 accatctaat ggatgtgaca ggtagtgttg aggaggcgcg tgcaagctac atcattcgtg
    18421 attttgaaaa agatgccttt gaagcgcgta aagcatccat gcaatctatc gctgataaga
    18481 tgaatgaaga acttgggagc aaccgtgtca ctctcaactt gacagaccag tactacaata
    18541 tgaaagaagt cattgaaaaa gatatgactc caattaccat tgctaaagcc gttatggaag
    18601 atctaggtat cacgcctatt atcgaaccaa tccgaggtgg aacagacggc tctaagattt
    18661 cctttatggg aatcccaact ccgaatatct ttgcaggtgg cgaaaatatg cacggacgtt
    18721 ttgaatacgt tagccttcag actatggaac gtgcagttga taccatcatt ggcatcgtag
    18781 cttataaagg ctaaaaagac gaggtagctc agctacttcg cctttctttt tattctactg
    18841 gtttttcttg atttccagta gttgtagaag attctgttgt ttcattttct gaagttgatt
    18901 cagcaggttt agaatctctt gtattgcttg gtttgttttc gtcgctagca gtttcaatgt
    18961 tagattctgc agttgcgttt ggttggttct cagcactggt gttatcacta tttgcttcag
    19021 catttcttgc tggacttgtt tcttcacttg cgctagcttt tgactggatt tgatgattca
    19081 aaactagaat agcttttgtc gattcaagta aagctgtttt gtctttactc ttagcagaaa
    19141 gttgatctaa taatgcatcc accttatcaa agtccgcatc agatccatta ttactttcta
    19201 aataagagtg aagcgacatg agaatatcgt agagtttttg atagagtaca agtgtctgag
    19261 aatcttgctc agcattttcc ttttcttgtt gaagggcgct agcgatacga gtcaaaacat
    19321 cttttacctg actgtttact tcatccaagt ctgcatcagc cttgtttgtg gcagctttta
    19381 gattttctac ttcttctgcc aaggattgtc tgattccttc ttcatggatt tgttccaaga
    19441 gttgatttgc cttgctcaaa agactttcta cttcttcctt gctatctgtc gcagattatt
    19501 ggttgctatc taccatgtac tcctaaaaca ggagagttat aatccaagat tacaaggcct
    19561 tacagaaata agaaatccag ataagacaat gttcgtccaa gacgctattc gcttcgcaca
    19621 acagcacgga ttcaatatgc tttaatttta aagtttaggt gtcaagacct ctttttagtg
    19681 tgcccaaaat ttagagaagt aatcaatcaa ctaactttta tttttttcaa actttcagta
    19741 aactgaccta aagctaactc aatctgtctt tgtagatgct tctgctatca gctagaagtt
    19801 gatctacttt tgccaagact gccttctcat caaaagttcc aggttgatag ttggattgca
    19861 gggatggaat cttgtttttc aaagccgctt catatccctt agtttgaacc ttgatgtagt
    19921 gattgtggtc gccatgagga atcacaaaac cttctgaatc ttcacttata attcgattgg
    19981 catcaaaacc atgaccatct tcttcctcat ggtggacatg tagtgacgga ttacttaata
    20041 cagaactaga agaacttcct gcctcttccg tgttagagtg tgatggggga ttgttaagag
    20101 atgacttagg aatatagtga tagtgatccc catgtcttac tatataagca tcacctgtat
    20161 ctctgacaat atcattaggg ttaaagacat atgtggctgc taattcacct gccgacaagt
    20221 cactctcagg aatgaaatga tagtgaccac catgtggtac tatagtagat tgaaatagaa
    20281 tatgagcaaa ttgataaggg gattttaaag taatttctaa caatgattta gaaactatga
    20341 tgtgctattc taaattcaac tcactatata taaccatcat cggtagtata acgtccctgt
    20401 aattttgcta cagatacttc tgcactagct cctttatcct ctttaccatg ttcttgtttt
    20461 tggcgattga tttcatcttt tgttcgtaca ttttctgcat gagcttgatc tttaaggtaa
    20521 acataatact ttccatctac cttaatacta tatcctccct taacctaact gacgatatct
    20581 tgatctttcg gctgatagtt gggggctttc attaatggct cttcactaaa gagcgcatca
    20641 aaaggaactt taccattata gcagtgataa tgatcgccat gagaagttac ataaccttga
    20701 cctgtaatct taataacaat ttgttttgct tgaattcctt ctttttgact aacctagtct
    20761 ggagtcaaat tttcagtctt cttagtgtct ttattactgt ttacatatga aacacgattt
    20821 ttatctgtat tggtctgtta gctatgttgg ttcagagcat aaacacacag acttaaggaa
    20881 aggataacag cagatccagc tgctatatat ttcttttt
//
LOCUS       DAVLGK010000038        20561 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLGK010000038 DAVLGK010000000
VERSION     DAVLGK010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20561
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.038"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            104..355
                     /locus_tag="VXE01_001591"
     CDS             104..355
                     /locus_tag="VXE01_001591"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750469.1"
                     /translation="MFQLGDKTRIIFAIIGASCILVSMYLIPLIKTENKFWEILLFIL
                     GVLLIGIALLSQKKINFEIVLVSSQSFIASGLELLSFKQ"
     gene            501..875
                     /locus_tag="VXE01_001592"
     CDS             501..875
                     /locus_tag="VXE01_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV0750470.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            1083..1985
                     /locus_tag="VXE01_001593"
     CDS             1083..1985
                     /locus_tag="VXE01_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750471.1"
                     /translation="MMRKLIVFLLMLPLFVLWLELHVLVNNLLLNLEFPLDFVISMSL
                     AFCSLILSKIALDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSV
                     DDLKSRMIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            2041..2394
                     /locus_tag="VXE01_001594"
     CDS             2041..2394
                     /locus_tag="VXE01_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0750472.1"
                     /translation="MELVLPNNYVVIDEEEMMYFDGGAYLSKRACQGICVALAMSPGT
                     FIALTGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            2391..3119
                     /locus_tag="VXE01_001595"
     CDS             2391..3119
                     /locus_tag="VXE01_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750473.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            4253..4756
                     /locus_tag="VXE01_001596"
     CDS             4253..4756
                     /locus_tag="VXE01_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750474.1"
                     /translation="MKLLDCILDYQERFNRKACQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQAGVFILEDFRNILLYNDVIERISLYEFIGDIFYFKITSCC
                     IVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            5042..6910
                     /gene="pspA"
                     /locus_tag="VXE01_001597"
     CDS             5042..6910
                     /gene="pspA"
                     /locus_tag="VXE01_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEV0750475.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTFVRAEESPVASQSKAEK
                     DYDAAKKDAKNAKKAVEDAQKALDDAKAAQKKYDEDQKKTEEKAAREEETAKKVNDAA
                     LAQQKAYAEYIKANQEQGRVRKEKLAEAQRKIDEATKKLEEAKKEFQTVRQTIVIPER
                     EKLAETKKKAEEAEQKEPELTKKLEEAKVKLEEAEKKATEAKQKVDAEKYALEAKIAE
                     LEYEVQRLEKEIKEIDESDSEDYLKEGLRAPLQSELDTKKAKLSKLEELSDKIDELDA
                     EIAKLEKDVEDFKNSDGEQAEQYLVAAEKDLDAKKTELEKTEADLKKVANEPETPAPA
                     PKPETPAPAPEAPAPAPAPKPEQPAPAPKPEQPAPAPKPEKSADQQAEEDYARRSEEE
                     YNRLTQQQPPKAEKPAPAPAPKPEQPAPAPKTGWKQENGMWYFYNTDGSMATGWLQNN
                     GSWYYLNSNGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEVSGAMKASQWF
                     KVSDKWYYVNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATG
                     WVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            7311..8432
                     /gene="mnmA"
                     /locus_tag="VXE01_001598"
     CDS             7311..8432
                     /gene="mnmA"
                     /locus_tag="VXE01_001598"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV0750476.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLGKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            8573..9028
                     /locus_tag="VXE01_001599"
     CDS             8573..9028
                     /locus_tag="VXE01_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0750477.1"
                     /translation="MTQQNFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            9038..10951
                     /gene="mnmG"
                     /locus_tag="VXE01_001600"
     CDS             9038..10951
                     /gene="mnmG"
                     /locus_tag="VXE01_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV0750478.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMILPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQDKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            11155..11232
                     /locus_tag="VXE01_001601"
                     /pseudo
     CDS             11155..11232
                     /locus_tag="VXE01_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(11330..13009)
                     /locus_tag="VXE01_001602"
     CDS             complement(11330..13009)
                     /locus_tag="VXE01_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0750479.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRNLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(13011..13244)
                     /locus_tag="VXE01_001603"
     CDS             complement(13011..13244)
                     /locus_tag="VXE01_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV0750480.1"
                     /translation="MIYKIFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            complement(14062..14214)
                     /gene="cibB"
                     /locus_tag="VXE01_001604"
     CDS             complement(14062..14214)
                     /gene="cibB"
                     /locus_tag="VXE01_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV0750481.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(14216..14401)
                     /gene="cibA"
                     /locus_tag="VXE01_001605"
     CDS             complement(14216..14401)
                     /gene="cibA"
                     /locus_tag="VXE01_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV0750482.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            14579..15262
                     /gene="tsaB"
                     /locus_tag="VXE01_001606"
     CDS             14579..15262
                     /gene="tsaB"
                     /locus_tag="VXE01_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV0750483.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDFDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVAPF
                     VEQIQEYLPRTNFKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            15259..15696
                     /gene="rimI"
                     /locus_tag="VXE01_001607"
     CDS             15259..15696
                     /gene="rimI"
                     /locus_tag="VXE01_001607"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV0750484.1"
                     /translation="MIEIKRIQQRPDLAQAIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYVLAYDGAEVIGFLAVQENLFEAEVLQIAVKEAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNHRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            15686..16696
                     /gene="tsaD"
                     /locus_tag="VXE01_001608"
     CDS             15686..16696
                     /gene="tsaD"
                     /locus_tag="VXE01_001608"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV0750485.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMVAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(16742..18042)
                     /locus_tag="VXE01_001609"
                     /pseudo
     CDS             complement(16742..18042)
                     /locus_tag="VXE01_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(18318..18669)
                     /locus_tag="VXE01_001610"
                     /pseudo
     CDS             complement(18318..18669)
                     /locus_tag="VXE01_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18776..19069)
                     /locus_tag="VXE01_001611"
                     /pseudo
     CDS             complement(18776..19069)
                     /locus_tag="VXE01_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            19312..20516
                     /locus_tag="VXE01_001612"
                     /pseudo
     CDS             19312..20516
                     /locus_tag="VXE01_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
BASE COUNT         6367 a         3581 c         4500 g         6113 t
ORIGIN      
        1 gagcagaata ttgatgatag tttaaatagc tcgcaaccat tatctttatc tttagccatt
       61 tcagaaatcc aacttttgct tgaagtgtat atggggatca aacatgtttc aattaggaga
      121 taaaaccaga ataatatttg ccattatagg ggcaagttgc atattagtca gtatgtatct
      181 tattccactt attaaaactg agaataaatt ttgggaaata cttttattta tattaggtgt
      241 attgctaatt ggaattgcgt tactaagtca aaaaaaaata aattttgaaa tagtattagt
      301 gagttcgcaa tcatttattg ctagtggttt agaactgtta agtttcaaac aataattgat
      361 tttaaacctt aggtaaccta taaaaacaaa taaggtagag aaaggatatc ttatataggt
      421 agctaagtga taaaaacaca gtcgtctatc acttgttagg aaactatcct aactatgctt
      481 aataaaaaag gagaaaataa atggaactcg tattaccaaa taattatgtt gctcttgagc
      541 aagaagagat gatgtatctt gatgggggat tttctattct gagatggcct gttgcaacag
      601 ccattaatat agcttttaat ggtgttttag gtggaggagc aatcagtcta gttagaaatt
      661 atattcgtaa ttatggtttg cggcgagtta caagcgcaat tgctggagca gctgcaagat
      721 atgttggggt acgagttgca aatagagtgg caggatttgc actgtctgct attaatggat
      781 ttgcagcttg gatgtcaatt ggcgatgcta ttacaacaat ctgggccaac aatgatgtaa
      841 ataggagaga cccaaattta aacgccttgt ggtaactaga tatgggtatt aaaatggaaa
      901 aaatttttgt tattattttt tttgtatgtc tatttatatc atccataact tttttagcct
      961 atgattttgt tagcgaagaa ataaaaaagt tgattatttg gattaatgtc gtttttttga
     1021 ttttaatcat agcaatgata atttatccaa aattaagaaa atgataagga cactgtaaaa
     1081 ttatgatgcg taaactaatt gttttcttac taatgctccc tctttttgtc ttgtggctag
     1141 agttgcatgt cctagtgaat aacttactat tgaatctaga atttcccctt gattttgtga
     1201 ttagtatgag tcttgctttc tgtagtttga ttttatcaaa aatagcttta gacatactat
     1261 acgcattgaa agatttgtac aagaaagaag ctcttattac gatttttcct tttattttta
     1321 taggcaggaa gaaagtaaat gtgaggttct caccctattt ttcattccat cgaaaaagtt
     1381 tgtcggttga tgatttaaaa tctagaatga tatggagttt tattcttgaa atagctatta
     1441 tcctagtatt tattttaaaa attccttttg caatcatcat gcttactaca atatttttct
     1501 ggactataat ggatatcaat catctcgttt ttaataagac ggaatttctt tttaatcaaa
     1561 ataaatggga aaaagaagat tcgtttgaaa gcgatttgac gaaaacgtta aaggataaga
     1621 tacaaaaatc agatctcagt tattctgact taatgtctct tcagctgtat gatgcgatga
     1681 accaatccac ctttttaacg gatagtgaac tttttgagga tattctgagt aaaattgaag
     1741 attctcataa cacccttctg tgtacaggtc ttgtcgagtt actgctgtat gagatttcta
     1801 ttagtaacaa taacaactgg caagaaaagg ttgataaaat taggatacac ctcatcagaa
     1861 tcaatcaatt agattttttc tattatacaa gttggttaag gcaaaatttt gatttctgta
     1921 tgaatagaga gtatcataaa atgaaatctc ggaaattatt actgagtaat aaaaagatag
     1981 tttaagttcg tcctatttgt aaaacaaatg aaacaatttc aactaaggag gagaaaacaa
     2041 atggaacttg tattaccaaa taattatgtt gtgattgatg aagaagaaat gatgtatttt
     2101 gatgggggag cttatttaag caagcgtgct tgtcaaggaa tttgcgtagc tttagctatg
     2161 agtccaggaa cttttatagc attgactgga gctgcagttt taaccaaaaa actaataaac
     2221 tatattaagg ttggaggtct tggaggctgg cttattggtg cagcagcagg tgtattggct
     2281 acagcagcag gaaaaatagc ttactgtatt ggatatggtg ctcttaatag aggttgtgat
     2341 attagcggga acccttatcc ttgggatgga tttatatctg cgacagtaag atgaataatg
     2401 tagataagat tcgaaaaata catattatcg tatgttggat gtatatattt ttatcattca
     2461 gggcgattat aaatgacacg gagtattttt tgcttatttt tttagctttt atctactcaa
     2521 tagtatcact acctctatat tctgtgaaaa ataaaatagt atctatctgt ctagccataa
     2581 attcgattct gttaatgagt ttccccattt taatcaataa gtttttccca gaaagttttt
     2641 tgacttatac cgtattaata agtgttttta tcctagagtt agcaatcttt catttaattg
     2701 gggaagattt tgctactaaa ttgactaacg aatataagaa aattagtcag tttagaagca
     2761 aggtgtctca atctccttgg ataaaatatt tagagatttc tagttttata ttaactatat
     2821 ttccatctat tctttacggt acagttgata atcgtgtatt ggctcttatc tttttgataa
     2881 aaatttgtgt agatactacg ataaaatttt tattcatcag attatttgac acaagtactt
     2941 taatgaagag gagaatattt tttcttttcg cattggatgt tatagcttac ttatttttag
     3001 gatatctttt agtgattcaa aaagcaggct atttgttttc ggttttactt cttttttcta
     3061 atttttcagt tccatttatc aaagaaaagg aattcgaatt atttaaaaat agcaagtaat
     3121 agaaacatag gttaaatctt agaacggctt aaaatcagat atgataaagg gaaatagtct
     3181 tatctaggta actaagtgct acaaacacag tcgaggatca cttgttagga ttacatttta
     3241 atcatgctta ataagaatgg agaattccta tggggattgt attactctga agtttcgaat
     3301 accttagttc tcgtgatttt gagctattct aggtttagaa tccttcagaa tgtaaaattt
     3361 taagcagtca aagacttaga atagcccgaa aacatttatt ttatagcaat tctaggctta
     3421 gaattgctca tatatatgta tttgagctgc tcgatagtta ggacagcttt attctgagaa
     3481 atctgagcta tcaatgcttc agaatagtat ttcgccaatg gtttttattg aagaggtgat
     3541 tgttttatga tagtctaaaa taaaactgat ttatggagta aatggagaat cgttacatga
     3601 aacatttttt tgcaggaatt ggtgagataa aacttgttgg ctacttattg tatatatgtg
     3661 taggactagc ccctcttttt catatatatg tcataggttc ggaactgagt tttgtgaaaa
     3721 tagtgttatc tattttagga gttatatttg taagtatgtt aactattgct cgaatttatc
     3781 ggacttttct ataaagaata gtttggactt gaactgtatc taaaaacaga ggttggtcga
     3841 ttatcagcct ctttcttgtc gttgaaaaga gtgagatata ttgacttttg aaaaaaagat
     3901 gtcataattg agttgggata aacctaaaag taatatagta gattgaatct ggaatagtcc
     3961 gttatgactg ttaaaatatt tctagaaatt aatttgactt tcctaatcga tttgttcaca
     4021 tcttgtttca atctactata ctttctcgtt aaaccgttcg gcaattcatg gtgacatgga
     4081 cacatagtag taagcacact atgtggcttg gcagagctaa aaactgttcc cttgtgataa
     4141 gcctaataag cacaacatag ggagttagag aagccgactc taatcaacca ctttgggcag
     4201 tagtgagaac tgccccgtgc ttttttattt tgagaaaata tggagtttgt cgttgaaatt
     4261 acttgattgt attttggatt atcaagaaag attcaataga aaagcatgtc aagtatcaac
     4321 gaattataag tatttagaga ctttcaaagt gaatttttgc ctgactgatt tacatcattt
     4381 atttggctta cacaaaatca cacgagatta tgctagtcaa acaaaacctg ctattcaagc
     4441 tggtgttttt attttagaag attttagaaa tatcctattg tacaatgatg taatcgaaag
     4501 gatatcttta tatgagttta taggtgatat tttctatttt aaaataacaa gttgttgcat
     4561 cgtagctaag gatttatcta aaaatactat gaaattggac gtcatatttt ttgaggataa
     4621 aaataaaaga tccgcagttt taggtttacg aagagacaaa agcggagtat ttaaaccagt
     4681 tactctacat tttacaagcg ctaagaaata tgctaaagtt cgtaaaacag atgtgaaaga
     4741 aatgaaatgg ctataaagat tgtccgcagg cttaagcttg cgttttttgt tgtttaacga
     4801 aattaaaaaa caagctctct catcggaagt gtttttatag gaatgaagga agatgatgct
     4861 atgtttaaaa agagaatcga aaagggcaaa agtagtgtct ttatcttttt ggagtagaag
     4921 cttatgatat agaaatttgt aataaaaatg taatataaaa catttgacaa atatttacgg
     4981 ggggagtata cttaatataa gtatagtcta aaaatgacta tcagaaaaga ggtaaattta
     5041 gatgaataag aaaaaaatga ttttaacaag tctagccagc gtcgctatct taggggctgg
     5101 ttttgttgcg tctcagccta cttttgtaag agcagaagaa tctcccgtag ctagtcagtc
     5161 taaagctgag aaagactatg atgcagcgaa gaaagatgct aagaatgcga aaaaagcagt
     5221 agaagatgct caaaaggctt tagatgatgc aaaagctgct cagaaaaaat atgacgagga
     5281 tcagaagaaa actgaggaga aagccgcgcg agaagaagaa actgctaaga aggtaaacga
     5341 tgctgcttta gcgcaacaaa aagcatatgc agaatatata aaagctaatc aggaacaagg
     5401 tagggtccgt aaggaaaaat tagcagaggc gcaaagaaaa atagatgaag cgactaaaaa
     5461 actagaagaa gctaagaagg agtttcaaac tgtaagacaa acaatagtaa ttcctgagcg
     5521 agagaagttg gctgagacta agaaaaaagc agaagaggct gaacaaaaag aaccagaact
     5581 tactaaaaaa ctagaagaag ctaaagtaaa attagaagaa gctgagaaaa aagctactga
     5641 agccaaacaa aaagtggatg cagaaaaata tgctcttgaa gctaaaatcg ctgagttgga
     5701 atatgaagtt cagagactag aaaaagagat caaagagatt gatgagtctg actcagaaga
     5761 ttatcttaaa gaaggcctcc gtgctcctct tcaatctgaa ttggatacca aaaaagctaa
     5821 actatcaaaa cttgaagagt tgagtgataa gattgatgag ttagacgctg aaattgcaaa
     5881 acttgaaaaa gatgtagaag atttcaaaaa ctcagacggt gagcaagctg aacaatatct
     5941 tgttgcagct gaaaaagact tagatgctaa aaaaactgaa ttagaaaaaa ctgaagcgga
     6001 ccttaagaaa gtagctaatg agccagaaac tccagcccca gctcctaaac cagaaactcc
     6061 agccccagct ccagaagctc cggctccagc tcctgcacca aaaccagagc aaccagctcc
     6121 tgcaccaaaa ccagagcaac cagctccagc accaaaacca gagaagtcag cagatcaaca
     6181 agctgaagaa gactatgctc gtagatcaga agaagaatat aaccgcttga ctcaacagca
     6241 accgccaaaa gcagaaaaac cagctccagc tcctgcacca aaaccagagc aaccagctcc
     6301 cgcaccaaaa acgggctgga aacaagaaaa cggtatgtgg tacttctaca atactgatgg
     6361 ttcaatggct acaggttggc tacaaaacaa cggttcatgg tactacctca acagcaatgg
     6421 cgctatggcg acaggttggg ctaaagtcaa cggttcatgg tactacctca acgctaacgg
     6481 ttcaatggca acaggttggg tgaaagatgg agatacctgg tactatcttg aagtatcagg
     6541 tgctatgaaa gcaagccaat ggttcaaagt atcagataaa tggtactatg tcaacagcaa
     6601 tggcgctatg gcgacaggat ggctccaata caatggttca tggtactacc tcaacgctaa
     6661 cggtgctatg gcaacaggtt gggctaaagt caacggttca tggtactacc tcaacgctaa
     6721 cggttcaatg gcaacaggtt gggtgaaaga tggagatacc tggtactatc ttgaagcatc
     6781 aggtgctatg aaagcaagcc aatggttcaa agtatcagat aaatggtact atgtcaatgg
     6841 cttaggtgcc cttgcagtca acacaactgt agatggctat gaagtcaatg ccaatggtga
     6901 atgggtttaa gccgattaaa ttaaatcatg ttaagaacat ttgacatttt aattttgaaa
     6961 caaagataag gttcgattga atagatttat gttcgtattc tttaggtacc tgtcttatga
     7021 tttcaggaaa tgtcattaaa aaaacgactc cttttctcta acttgaaaaa tagattagag
     7081 aaaatgggtt gttttattta ttatagttat ttgaatgaag ataagaagaa ggtatactca
     7141 cgtcattcac ataatctgta tattgactat aagttttaaa aaacaatttt taagctcttc
     7201 cttgtcttct ctaaccaagc gtgttataat gaatactgct caagcgacct tcaatcgtga
     7261 agcacacacg accttcaatc gtgaataaac gaatagatgg gagacttacc atgagtgata
     7321 actctaaaac acgtgttgtc gtggggatga gtggtggtgt tgattcgtcg gtgacggctc
     7381 ttttgctcaa ggagcagggc tacgatgtga tcggtatctt catgaagaac tgggatgaca
     7441 cagatgaaaa cggcgtctgt acggcgaccg aagattacaa ggatgtggtt gcggtggcag
     7501 accagattgg cattccctac tactctgtca attttgaaaa agagtactgg gaccgcgttt
     7561 ttgagtattt cctagcggaa taccgtgcag ggcgcacgcc aaatccggac gttatgtgca
     7621 acaaggaaat caagttcaag gcctttttgg actatgccat aaccttgggg gcagactatg
     7681 tagcgactgg gcattatgct cgagtggtgc gtgatgagga tggtaccgtt cacatgcttc
     7741 gtggcgtgga caatggcaag gatcagacct atttcctcag ccaactttcg caagaacaac
     7801 ttcaaaaaac catgttccca ctaggacatt tgggaaagcc tgaagtacgc agactagcag
     7861 aagaagcagg cctttcgact gctaagaaga aagattcgac agggatttgt tttatcggag
     7921 aaaagaactt taaaaacttc ctcagcaact acctgccagc tcagcctggt cgcatgatga
     7981 ctgtggatgg tcgcgatatg ggcgagcatg caggtcttat gtactataca atcggtcagc
     8041 gtggcggact cggtatcggt gggcaacacg gcggtgacaa tgccccttgg ttcgttgtcg
     8101 gaaaagatct aagcaagaat attctctatg taggacaagg attctaccat gattcgctca
     8161 tgtcaactag cctagaagcc agtcaagtcc actttactcg tgaaatgcca gaagagttta
     8221 cgctagaatg tacggctaaa ttccgttacc gtcagcctga ctctaaggtg accgtccatg
     8281 tcaaaggaga caaggcagag gtcatctttg cggaaccaca acgcgcgatt acaccaggac
     8341 aggcagttgt cttttacgat ggcgaagagt gtctaggtgg tggtttgatt gacaatgctt
     8401 accgcgatgg acaagtttgt cagtacattt agattgacaa attttctcaa tttgctacaa
     8461 taataacagc aatagaaatg atggtcaaag ctcatggatg ttgcaggctt ttttgtcctg
     8521 cacttctttg tagttttgac tgtttttgtg tcgtttaagg gaaaggacaa gaatgactca
     8581 acaaaacttt cggacaaaag tagacaatac ggtttttggt gttcgggcga cagccttgat
     8641 tgtccaaaat cacaagcttc tagttaccaa agacaagggc aagtattaca ctattggagg
     8701 tgcgattcaa gtcaatgaaa gcacggaaga cgcggtagtc cgtgaagtga aggaagaact
     8761 gggtgtcaaa gctcaagctg ggcagctagc ttttgtggtt gaaaatcgtt ttgaacaaga
     8821 cggcgtttcc tatcacaata tcgagtttca ttatctggtg gatttgcttg aagatgcccc
     8881 gttgaccatg caggaagatg agaaaaggca gccctgtgag tggattgact tggataagct
     8941 tgaggatatc cagctagttc cagccttttt aaaaacggcc ctaccagatt gggaaggcca
     9001 actaagacac attcatcttg aggaatagga gagaaacatg acttatcatt ttactgaaga
     9061 atacgatatt attgtaattg gtgcgggaca cgctggggtt gaggcttcct tggccgctag
     9121 ccgtatgggc tgtaaggtcc tgcttgcgac catcaatatt gaaatgctgg ctttcatgcc
     9181 ttgtaatccc tctatcggtg gttctgccaa ggggattgtc gtgcgtgaag tcgatgccct
     9241 cggtggcgag atggccaaga ctattgacaa gacttacatc cagatgaaga tgctcaacac
     9301 agggaagggg ccagctgtcc gtgctcttcg tgcgcaggct gacaaggaac tttactctaa
     9361 ggagatgcgc aagacagttg aaaatcaaga aaatctgacc cttcgtcaaa ccatgattga
     9421 tgagattttg gtggaagatg gcaaggttgt cggtgtgcgt acagccaccc atcaagaata
     9481 tgctgctaag gctgttattg tgacgacagg gactgctctc cgtggggaaa ttatcatcgg
     9541 agacctcaag tactcatcag gtcctaacca cagcttggct tctattaacc tagctgacaa
     9601 tctcaaggaa ctgggtctcg aaatcggtcg tttcaagaca ggaacccctc cacgtgtcaa
     9661 ggcctcttct atcaactacg acgtgacaga aatccaacca ggagatgaag cgcctaatca
     9721 cttctcatac acttcacgtg atgaggatta tgtcaaggac caagtgccat gctggttgac
     9781 ctataccaat ggtaccagtc atgagattat ccaaaacaac ctccaccgtg cgcctatgtt
     9841 tacaggtgtg gtcaagggag tgggacctcg ttactgtcca tcgattgagg acaagattgt
     9901 gcgctttgcg gacaaggaac gtcaccaact cttccttgag ccagaaggac gcaatacaga
     9961 ggaggtctat gtccaaggac tttcaaccag tctgcctgag gatgtccaac gtgacttggt
    10021 tcattccatc aaaggtctgg aaaatgcaga gatgatgcga acaggttatg ctattgagta
    10081 tgacatgatc ttgcctcacc agttgcgtgc gactttggaa accaagaaaa tctcaggact
    10141 tttcactgct ggtcagacaa atggaacatc aggttacgaa gaggcagcag gccaagggat
    10201 tatcgcaggg atcaatgcgg ctctgaaaat ccaagataag cctgagttga ttttgaagcg
    10261 tagtgacggt tacattgggg tcatgattga tgatttggtg accaagggaa ccatcgaacc
    10321 ctaccgtctc ttgaccagtc gtgctgaata ccgtctcatt ctccgtcatg acaatgctga
    10381 tatgcgcttg actgagatgg gacgcgagat tggccttgtg gatgatgaac gctgggctcg
    10441 ttttgaaatc aagaaaaatc aatttgataa tgagatgaaa cgcctagaca gtatcaaact
    10501 caagccagtc aaggaaacca atgctaaggt tgaggagatg ggcttcaaac ccttgacaga
    10561 tgcagtgaca gccaaggaat tccttcgccg tccagaagtt tcttaccaag atgtggtagc
    10621 cttcatcgga ccagctgcag aggatttgga tgataagatt atcgaattga ttgaaacaga
    10681 aatcaagtac gaaggctata tttcaaaagc catggatcag gttgccaaga tgaaacgtat
    10741 ggaagaaaaa cgcattccag ctaatattga ctgggatgac atcgattcta ttgcgacgga
    10801 agctcgtcag aagttcaaac tcatcaatcc agaaaccatc ggccaagcca gccgtatttc
    10861 gggagtgaac ccagcagata tttctatttt gatggtgtat ctggaaggta aaaatcgtag
    10921 tatttctaaa actcttcaaa aatcaaaatg atacgtcgtc ggcttcttac gaatgagttc
    10981 aaagcttggc tttgattcat ctccaacctc ccatagttcc ccgaactatg ggagctaact
    11041 caagttatgc attttcctag ccttctggtc tgattttcat tgagttttaa tctcaaaaga
    11101 aagcatagag aaaaacagct ccgaagacgg ggctgttttg ttgacttgta ctcaatgaaa
    11161 atcaaagagc aaactaggaa gctagccgta ggttgctcaa agcactgctt tgaggttgta
    11221 gatagaactg acgaagtcag ctcaaaacac agttttgagg ttgtggatag aactgacgaa
    11281 gtcagtaaca tatatacggc aaggcgaagc tgacatggtt tgaagagtat tactcttcat
    11341 ctggtgtgag gatcatcggg atgatgatcg gttcacgttc ggtattttca tagaggaagg
    11401 ggcgaatagc gttgacaatg gcaccattga cagattgcac gctagcatcc ttatttttca
    11461 gtgcgatacg aatggcattg aagaggatac gctggctttg gcgaatcaag tcgccagact
    11521 ctctcatgta gacaaagcct cggctgagga tgtctggacc agatagaatc atctgcgatt
    11581 tgaagtcaac agttgcgact gccagaacga caccgtcttc agatagattg cgacgatctt
    11641 tgaggacagc tgcgccaatt tcaccgatac gatttccatc gacatagata tcttgggcgt
    11701 tgaaatgacc tgcgatacga gctgagtcag cagtaagggc aagcacatcg ccattgctca
    11761 tgataaagat attgtccttc tcaacaccag tatccactgc tagtccagcg tggacttttt
    11821 gcatgcggta ttcaccgtgg acaggcatga agtattttgg cttaatcaag cagagcatga
    11881 gtttttgctc ttgctgacca ccgtgtccag atgtatggat attgtttact ttaccgtgga
    11941 taacttcgac accagcttca gaaatgatgt taatcagctt gttgacgcta gtagtgtttc
    12001 cagggatggg actagaagag aagataacgg tatcacctgg ttgtaattgt acttgacggt
    12061 gggttccgtt ggcgatacga gagagggctg ccataggctc accctgacta cctgtacaga
    12121 ggataagaac ttctcctgca ggataatctt tgatttcatt tggctcgata aaggttccct
    12181 taggagcttt gatgtagcca agatcgattc cgttgacaat ggccttttcc atagaacgac
    12241 caaagaccgc aatcttgcgt ccagtcttaa cagcagcttc tgttgcctgc tggagacgga
    12301 agatatttga ggcaaaggat gcaaagatga tacgtccttc aataccttgg ataatcttca
    12361 taatggactg accaacgact ttttcagagt tggtaaaggt tggtacttcc gcatttgtcg
    12421 agtcagacag gagacagagc acgccttctt caccaagcgc agccatacga tgcaagtccg
    12481 caggttctcc aactggagta aagtcgaact taaagtcacc cgtacagacg attttccctt
    12541 gaggagtatg aatgacaatc cccaaaggct ctggaataga gtgagtcgtt ctaaagaaag
    12601 ttgccttgag atttttaaag gtcaactcgg tgttgtggtt gatttcgtaa agtttggcgt
    12661 tgcgcaagag gccgtgttct tcgagtttcc cacggatcaa agccaaggca agcggtccag
    12721 cgtagatagg gacatttgct tgcttgagta ggaacggaat cccaccaatg tggtcctcgt
    12781 gtccgtgtgt gattaaaaca gccttgacgc ggtcgatatt gtccacgatg taagagtagt
    12841 caggaatgac atagtcgata ccaagcaagt catcttctgg gaatttaatc ccagcatcga
    12901 cgatgataat ctcgtcttgg tattcaattc cgtaagtgtt tttcccgatt tctcctagac
    12961 caccgatggc aaaaacgccg acttcttcag gtttaagagt gtaggccata ttagaactcc
    13021 gtaatttcga aggcgccagt ttctttttcg taatcgagca atttgtcaga caagagttcg
    13081 atatattcga tattgtactc tgggcgattt tcttcgacaa gttggcgagc agtgatacgg
    13141 ccctcaagtt ctgagctggc atcgatgtct aggtaaagcg cgcgtgttgt ttcacggcgt
    13201 gggctacgtt cttttgtttc ttgataaaaa attttgtaaa tcatatagtt cctttctatt
    13261 tacaggtcag cttattccaa acttttagca gatatttgct tgatttcatt ccattttgtg
    13321 tctagattga ccttgattcg ttacaattat ttcaattata ccacaaaatg aaaaattagt
    13381 aaaagacgga aacgagaaag ttaggggacg atttcttcgg taagcgtttg caaaaataaa
    13441 gaaaatgtgt tatgttgata acggaagtga agtttattac ttgtcataat tccatataga
    13501 ttttaagtca aggaggttgc cctatgtata acttatttgc ttttgttatc ggagttcgtt
    13561 tgctagcttt tatcgttttt gttgcttgcg tttatgaagg aaatcttcta tttgccaaac
    13621 tggaacgatg acaaaccaag ttcttgtgga aaatgacctt tgtgactctc tactcgcttt
    13681 ttctcctcct cgtgacctat gtcgtttggt ttgtatttta ctttggatta aatgcttaga
    13741 tgccctgctt atgctggttt tttttgtttg gggatgtaga gatagtagat ttacgacacg
    13801 aaaattccac cccatctatc aagataaggt ggtctttgca tttttctaac atgacatgac
    13861 aatggaattt tcaaagctta ttatttttat gggagtcatt gttctgctca aaaatagagt
    13921 tgaagcataa aaataaaaca atacaaacag ataaatcgaa tggtaaaggg atagtagtaa
    13981 tgttcaaatc attgagaatg ctgagcaaac tgtaagagat gaagacaata aaatttatcc
    14041 ttctaaaaat gtgtttctta tctagcatga cttaccaaac tttttacgaa ggtcttttcc
    14101 aatggtataa cctgccataa ataaagcgat accaacacct acaccaaagc cacccttgat
    14161 ttcttgcaat tccttattag aaatttcacg atagttgttc aaatctttca tcatattaat
    14221 ctcctcctaa aaaataacca gctgccaaac cagaacctat aagtgctgtt ccacctgcaa
    14281 tagccttcca agatactgct actccaaaga taaccaaggg agcgagaccg ccatcaatat
    14341 ctgataattc attttcagat aaggataaaa attgattgtc aagaatgtca aaatttgtca
    14401 ttgaactttc ctcctttttt cttgttcact tttatattcg gaaaagaaaa ggaaaagtga
    14461 gcattttttt aaattatttt tagttaagtg agggcactct tgtctggggg caaagaaaat
    14521 tcccatgtgc catcttttgt agtataatag taagcagaca aaaagatagg aatgtgttat
    14581 gaaagtatta gcttttgata cgtccagcaa ggctctttct ctggctattt tagaggataa
    14641 gcaggttctt gccgagacga cgattaatat taagaaaaat cacagtatta cccttatgcc
    14701 tgccatcgat tttttgatgg caagtttgga ttggacaccc aaggattttg accgaatcgt
    14761 ggtggctgaa gggccaggta gctacacagg tttgcgaatt gcggtagcca ctgccaagac
    14821 cttggctcat actctgaaca ttgagttagt tggtatgtct agcctcttgg ctctggtgcc
    14881 atatcaacaa gaaggcttgt tcgttccttt gatggatgcg cgtcgcaaca atgtttatgc
    14941 aggattttat gaaaatgcta aacctgtcat gccagaagcg catctgcctt ttgagcgagt
    15001 cattgagcta atcaagggcg ctagtcaggt aacctttgtc ggagaagttg ccccctttgt
    15061 ggagcagatt caagaatact tgccaaggac taatttcaaa gaaaccttgc caaatgcagc
    15121 caatcttgct cttttagctt gggacaagga agcagactcc ttgcatgatt ttgtgccgaa
    15181 ttatctcaaa cgtgttgagg ctgaggaaaa ctggctcaag aaccacacag agtctggcga
    15241 gtcttacatt aaacgcctat gatagaaatc aaacgaatcc aacagcgacc tgacttggct
    15301 caagccatct acgctgttat ggcagctgtt tacccagtta gtccgtggac gctggaacaa
    15361 atccaagcag acctgtccca agaccagact tggtatgttc tggcttatga tggggcagaa
    15421 gtgattggct ttctagctgt tcaggagaat ctttttgagg cagaagtctt gcaaatcgct
    15481 gtcaaagaag cctatcaggg tcagggaatt gcgtcagcct tgtttgctca attgccgaca
    15541 gacaaggaaa ttttccttga agtcagacag tcaaatcatc gagcgcaagc attttacaag
    15601 aaagaaaaga tggcagtcat cgctgagcga aaggcctact accatgaccc agtcgaggac
    15661 gccatcatta tgaagagaga aatagatgaa ggatagatat attttagcat ttgagacatc
    15721 ctgtgatgag accagtgtcg ccgtcttgaa aaacgacgat gagctcttgt ccaatgtcat
    15781 tgctagtcaa attgagagtc acaaacgttt tggtggcgta gtgcccgaag tagccagtcg
    15841 tcaccatgtc gaggtcatta cagcctgtat cgaggaggca ttggcagaag cagggattac
    15901 cgaagaggac gtgacagctg ttgcggttac ctacggacca ggcttggtcg gagccttgct
    15961 agttggtttg tcagctgcca aggcctttgc ttgggctcac ggacttccac tgattcctgt
    16021 taatcacatg gctgggcacc tcatggtagc tcagagtgtg gagcctttgg agtttccctt
    16081 gctagccctt ttagtcagtg gtgggcacac agagttggtc tatgtttctg aggctggcga
    16141 ttacaagatt gttggggaga cacgagacga tgcagttggg gaggcttatg acaaggtcgg
    16201 tcgtgtcatg ggcttgacct atcctgcagg tcgtgagatt gacgagctgg ctcatcaggg
    16261 gcaggatatt tatgatttcc cccgtgccat gattaaggaa gataatctgg agttctcctt
    16321 ctcaggtttg aaatctgcct ttatcaatct tcatcacaat gccgagcaaa agggagaaag
    16381 cctgtctaca gaagatttgt gtgcttcctt ccaagcagca gttatggaca ttctcatggc
    16441 aaaaaccaag aaggctttgg agaaatatcc tgttaaaacc ctagttgtgg caggtggtgt
    16501 ggcagccaat aaaggtctca gagaacgcct agcagccgaa atcacagatg tcaaggttat
    16561 catcccccct ctgcgactct gcggagacaa tgcaggtatg attgcctatg ccagcgtcag
    16621 cgagtggaac aaagaaaact tcgcaggctg ggacctcaat gccaaaccaa gtcttgcctt
    16681 tgataccatg gaataaagag tggctctttg tcaagtgtag tgggtaggcg aaaagctgca
    16741 atctggagag tacgaaattc gtactctctt ttttgatgtt caaagtcatc aaaatccgtt
    16801 ttttaaaatt gttaaagttc cggaaaccaa aggctttgcg cttgataatc ttaatcaaat
    16861 tattggtcgc ttcaagttta gcgttggaat aaggcagctt aagtgcgttg ataatcttat
    16921 ctctatccct taaaaaagtc caaaagaccg tttgaaaaag cggatgaacc gttggcagtt
    16981 cttgctcaat caatccaaag aaatggtcgg cattcttctc ttgaaaatga aagagcagga
    17041 gttgatagag ttcgtagtga acctgtaatc cctcagagta agaaagcagc ttatctcgta
    17101 cttcccgatg ggttaagtgc attcgaaacg tgggctgata gaatcgtttc tgacagagct
    17161 tgaagctata ctggtgtagt aaatcagtcc agtggactga tttagcccga gcctagaaac
    17221 gaaaaagcga gggttccaaa agcgcttgag cgcccgatac tccaaggatt ttcggtcaaa
    17281 ttggttcatg atttggattc gtactcggtt catagctcgg ctcagatgtt ggacaatgtg
    17341 gaagcggtca agaacaatct tcgcctttgg aaagagttgc ttagcgagcc gataataagg
    17401 gctgtacatg tccatggtga tgacctcgac cagctcccga acctctctct gatagcgttg
    17461 gaaatggttt cgaatcaccg catgagttcg cccgtctaaa attgcgagga tggatttgga
    17521 ctcaaaatct tgggcaatga agctcatttt gctctttttg aagctatact catcccaact
    17581 cataactttt ggcaacttgg tccaatcggt ttcaaactta aattccctca gttttcggat
    17641 gacggtggaa gttgagaccg ccaatctgtg ggcaatctca gtcatagact gcttttcaag
    17701 gaggagctga gcgatttttt gtctcaccat gttggaaatc tggcaatttt tcttgacaat
    17761 ggatgtttga gaaacgacca ccttaaggca attcttgcac tgaaagcggc gctttttgag
    17821 atgcagtacc gtgggtaaac cctgacagtc gagaagcgga attttagagg ctttctggaa
    17881 gtcgtatttg atcatcttcc cttgacaatg aggacaagga ggagcggggg aatccaactt
    17941 tgcctgaacg actagatggg tttggtattt cagaacagac aagattttga tatttttgtc
    18001 tttcaatccg agcaaatctg tggtattctt aagttgttcc atatgaaccc tttctaatga
    18061 gttggttaga cgcttttcat tataggtcat atggggcttt ttttctacaa gaaacgaccc
    18121 tataattcct ggggtgggat tacccactac agaaattata gagccaaaac attccaaagt
    18181 cttgtctgac tctggaatgt tttctgttca cagttgtttt gtaactgcct aataagtaac
    18241 cgcgctataa cgaggtatct accgagattg tcaattctcc agtatactgt tataaaaaac
    18301 aaaactggag gattttttta tgtcccccca tcgtcccatc gactgttccg tagctgccca
    18361 ataacggagt atagtcggct gaaacaagaa taggacaaaa gtgcctcaag aaaagcatcg
    18421 taatttgaca atattattct gagatgtttt tgatgtaagc ccatattttc tcaatgggat
    18481 tatactcggg tgaataggta ggaagtggta acagtctatg ccctgctcct tacacatgtt
    18541 cattctgtga aaccttgcat tgtccataat gataagggat ggtgtatcta aagtaggtag
    18601 taagaatttt tggaagcaag cttcgaaaaa gtcactcgtc atcgtatctt tataggtcat
    18661 cggagccata gtatattgaa acaaaaaagg gcattagtac ttctataaca gtatcgcaat
    18721 ctctggtgtg cgttgtctcg atcttaattc aaataattat atcttcttcc agagagacta
    18781 actgcctgct caaggctcga tcatattcga gataaaaata ggtctcaacc cctgtctcat
    18841 aaatataaat aggagtcagg tagcttaagt gattcaattc tttaaggaac cgatttactt
    18901 tttctgggtc ttgttcgcag taggtacagc tcttttttag actatatccc atagccttta
    18961 gagcgtaatg aatagttgtt ggaggacagt tgaattcagc agctatttca gtcaaataag
    19021 catcgggatg agtttcaata tagatcttta atttatctct atcaactttt tcaattaata
    19081 gtggaagttt tcttaaagtt agtgtgttga aacgttttta tacagtgcta aaatttgaag
    19141 tgtagtgcag atgtatttgt aatagtatta tagcaattct ttggagaagg tcgagacaag
    19201 agaaaatagg tatctttgag atataagcat gatttactat aaaattattg agttattcat
    19261 aaaaatttct ctatcaaata tcataatgcg tcgtttaagg agatggttac aatgcaatat
    19321 agttgtggaa aaataaatat taatatccct gatggatatg gagacattaa ggatatagtg
    19381 ttttcggctc atattatagt taggtataat aatggacatt gtggaggtat agatccgcat
    19441 ataattggac tttgtaaaaa gcagatcaga aggatgtctc tatatcctat tttgataatc
    19501 gtatctagag attcaaaggt tattgatgat tataaaaatt tagatattgc ctatgttgat
    19561 tgtactcaat gttcaaataa ttttgaaact gccttacacg ttaaaaatat tttaaaatta
    19621 ttaaaaatcc aacttataca ctgtcatggc tactcaacta attatttttt atatatgtta
    19681 aaaaaacttg acaagaatgg atttggaaag gttaagacag tgataacatg ccatggatgg
    19741 gttgaatata acttaaaaaa gaaattcttg acttattttg atttttggac atattctatg
    19801 ggagatgctt ttatttgtgt atctgaaact atgaaaaaaa gattggagag tataataaaa
    19861 aataagaaga tagttgcaat aaataacgga attaatgtat caaatagcga tttagatgta
    19921 gtaggtgttc aagactttaa aaaagaattt tgtattccaa ataacaaaaa aatcatttgt
    19981 tatgttggaa ggttggatcc agaaaaaagg ccggatagat tccttgaatt tgcagaaaaa
    20041 ttatttttag tcagagaaga tgtgattttt attatggctg gaaatggtag tatgtgggct
    20101 gctttgaaag aaaaaatttg ctatttgaaa tgtagagata atttcaggtt acttggtgaa
    20161 atctatccag tactatagtt taccaaatat cggatttatt gtatattcct tctgatacag
    20221 aaggaatacc tatgtgtgtt ttagagtcaa tgtcacaagg aactccggtt ttagctagta
    20281 atgttggcgg gttaagtgaa attattgaac atagggttga tggattttta tttgagaagg
    20341 aagatgttga gggagtgtgt gcttgtgcta attttttact caatgattct gagtatttga
    20401 aatatatagg tgagaatagt aaatcaaaaa taagaaaaca tttttctgtg caaaaaatgt
    20461 ttgtagaaac catgagagta tatgatgaat tattagagaa gagtagtcat ggataggaat
    20521 atagatcaag aattagtaag tattataata ccaacacata a
//
LOCUS       DAVLGK010000039        20306 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLGK010000039 DAVLGK010000000
VERSION     DAVLGK010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20306
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.039"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(113..388)
                     /locus_tag="VXE01_001613"
     CDS             complement(113..388)
                     /locus_tag="VXE01_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV0750486.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(495..1334)
                     /locus_tag="VXE01_001614"
     CDS             complement(495..1334)
                     /locus_tag="VXE01_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0750487.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1476..2324
                     /locus_tag="VXE01_001615"
     CDS             1476..2324
                     /locus_tag="VXE01_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0750488.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2417..3334)
                     /locus_tag="VXE01_001616"
     CDS             complement(2417..3334)
                     /locus_tag="VXE01_001616"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV0750489.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3772..3977
                     /locus_tag="VXE01_001617"
                     /pseudo
     CDS             3772..3977
                     /locus_tag="VXE01_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4288..4581)
                     /gene="rpmA"
                     /locus_tag="VXE01_001618"
     CDS             complement(4288..4581)
                     /gene="rpmA"
                     /locus_tag="VXE01_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV0750490.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4598..4942)
                     /locus_tag="VXE01_001619"
     CDS             complement(4598..4942)
                     /locus_tag="VXE01_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV0750491.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4958..5272)
                     /gene="rplU"
                     /locus_tag="VXE01_001620"
     CDS             complement(4958..5272)
                     /gene="rplU"
                     /locus_tag="VXE01_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV0750492.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5308..5395)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5490..6089)
                     /locus_tag="VXE01_001621"
     CDS             complement(5490..6089)
                     /locus_tag="VXE01_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV0750493.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGVVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6556..6855
                     /locus_tag="VXE01_001622"
     CDS             6556..6855
                     /locus_tag="VXE01_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV0750494.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7037..8334
                     /locus_tag="VXE01_001623"
                     /pseudo
     CDS             7037..8334
                     /locus_tag="VXE01_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8596..9570)
                     /gene="pta"
                     /locus_tag="VXE01_001624"
     CDS             complement(8596..9570)
                     /gene="pta"
                     /locus_tag="VXE01_001624"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV0750495.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(9614..10510)
                     /locus_tag="VXE01_001625"
     CDS             complement(9614..10510)
                     /locus_tag="VXE01_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0750496.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFNHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(10507..11325)
                     /locus_tag="VXE01_001626"
     CDS             complement(10507..11325)
                     /locus_tag="VXE01_001626"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV0750497.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRNRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(11309..11980)
                     /locus_tag="VXE01_001627"
     CDS             complement(11309..11980)
                     /locus_tag="VXE01_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV0750498.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            12108..12677
                     /locus_tag="VXE01_001628"
     CDS             12108..12677
                     /locus_tag="VXE01_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV0750499.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            12790..13749
                     /locus_tag="VXE01_001629"
     CDS             12790..13749
                     /locus_tag="VXE01_001629"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0750500.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            13759..14874
                     /locus_tag="VXE01_001630"
     CDS             13759..14874
                     /locus_tag="VXE01_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0750501.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            14879..15226
                     /locus_tag="VXE01_001631"
     CDS             14879..15226
                     /locus_tag="VXE01_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV0750502.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            15234..15449
                     /locus_tag="VXE01_001632"
     CDS             15234..15449
                     /locus_tag="VXE01_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0750503.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            15532..16173
                     /locus_tag="VXE01_001633"
     CDS             15532..16173
                     /locus_tag="VXE01_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV0750504.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            16191..16880
                     /locus_tag="VXE01_001634"
     CDS             16191..16880
                     /locus_tag="VXE01_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0750505.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDTGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(16877..17557)
                     /gene="radC"
                     /locus_tag="VXE01_001635"
     CDS             complement(16877..17557)
                     /gene="radC"
                     /locus_tag="VXE01_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV0750506.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(17600..19891)
                     /gene="pcrA"
                     /locus_tag="VXE01_001636"
     CDS             complement(17600..19891)
                     /gene="pcrA"
                     /locus_tag="VXE01_001636"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV0750507.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(20082..>20306)
                     /locus_tag="VXE01_001637"
     CDS             complement(20082..>20306)
                     /locus_tag="VXE01_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0750508.1"
                     /translation="PQAQTPRKSSKLKPLTVEDKAYNHALSKERSKVENIFAKVKTFK
                     MFSTTYRNHRKRFGLRMNLIAGIINHELGF"
BASE COUNT         6240 a         4269 c         3670 g         6127 t
ORIGIN      
        1 caatattttc ggaacattca actttttaac tctatttatt actagatttc ataattaaaa
       61 agcctattgt atcaagcttt ctagcttggt cagtaggctt tttaaagact gattatttaa
      121 cagcgtcttt aagagcttta ccagctttga atgctggtac tttagaagct gcaattgtca
      181 tttctttacc agtttgtggg ttgcgacctt tacgttctgc gcgctcacga acttcaaagt
      241 taccaaaacc gatcaattga actttttcac cagctgcaag atagtcagct actgctgcaa
      301 atacagcttc aactgctgct gctgagtctt tcttagtcaa ttctgtagct tctgctactt
      361 tagcgatcaa atcttgtttg tttgccatgt taatgattcc tccaaataat ttctaattaa
      421 caaatataat catatcctaa aatccctttt aggtcaagtt aaaaacgcta tttcttccca
      481 ttttatttat ttttttagga gtggtaacgt atcaaaatag cccaagcgtt ctcacccgtg
      541 tgagtttgaa taatggaacc cgtttccaaa acagaaattg gcttttcaac ataagcttgt
      601 aagctttctt tcatctcttt tgcccaatca tcactaccag aatatgaaat tccaatctct
      661 gctacagcac gttcagaaag cgatgttatc aactcatcta accatttttt aaatgtttta
      721 gttccacgac ctttaaccat tggctgcaat tcatggtctt tcatttgcat gacaacacgg
      781 atattgagaa gagagctcaa caagccagtt acacggctaa ttcgtccacc tttgacaaga
      841 ttttccaaag ttgaaacacc aatataaagc tctgtatggt ttttaacctc ttctacatga
      901 cataaaattg cctccatatc tttaccttct tgagctaact tcgcagcctc aacaacttgg
      961 aatttcaggg cttggtcagt gaaggaacta tcaacaacag tcacatctgc agtagatagg
     1021 ctagcacctt ggcgtgctgc ttctaccgta cccgaaagag catgggacat atgaatagca
     1081 agaatctggc caccatcttt gcataggtct tcaaaaatct cagcaaagac acctacaggt
     1141 ggctgacttg ttttcggaag attcttactt tcttgcatca actgaagaaa tttaccttct
     1201 tctttcaaat ccgcatcaga ataaacaaca ttatcaatca ttacagataa tggaacaatt
     1261 gtaatatcta attgctttac tagttcaggt tcaatagtaa cagatgaatc ggttacaatc
     1321 ttaatttttg tcatagtatc aatctttcta ttttaggatt cagattggtt tccttacttc
     1381 taattatatc aaaaaaaaga ttaaaaatcc taatggagtc aatcaaattt tccgtaaaat
     1441 ttgatataat caacttataa gaaaagaggt gtcctatgat taaaaaaatt taccccattt
     1501 ttaccatttt actaggtgct gctatttatg cttttggact gacttatttt gtagttcccc
     1561 atcatctctt tgaaggaggg gcgacaggta ttaccctcat cacattttat ctttttaaaa
     1621 tccctgtttc cctcatgaac ctgctgatta atattcccct tttcatccta gcttggaaga
     1681 tctttggagc caaatccctc tattctagtt tactaggaac cttagctttg tccggctggt
     1741 tagctttttt tgagcatatt ccccttcata ttgatcttca aggtgattta ctaatcacag
     1801 cccttatagc gggaatccta ttgggaattg gccttggaat tatttttaat gctggaggta
     1861 caactggcgg aactgatatt ctagctcgta ttctcaacaa atacactcat atatccatag
     1921 gaaaactgct ctttatctta gatttttgta ttctcatgtt gattctccta atcttcaagg
     1981 atttgagatt ggtttcctac acgcttttgt ttgattttat tgtttctcgt gttattgatt
     2041 tgattggtga aggaggatat gccggcaaag gctttatgat tatcacaaaa cgtcctgacc
     2101 aacttgctaa ggcgattaat gatgacctcg gaagaggtgt tacttttatt tctggtcaag
     2161 gctactatag taaagaaaat ttgaaaatca tttactgtat tgtcggaaga aatgaaattg
     2221 tgaaaacgaa ggaaatgatt catcgaatcg atcctcaagc ctttataact attacagaag
     2281 cccatgaaat cctaggagaa ggcttcacct ttgaaaaaga ataaaaagag gtagtgtcgt
     2341 gacctcaaaa gttagactaa atcatctatc ttttgggtta cagacaacct cttttttgtt
     2401 ttatttactc aagctcttaa gaccaattcc gagttacttc ttcatcagcc tttaactgat
     2461 ccactaattg gtcaactgag tcaaatttgg tcatatctcg aatgcgatca agccaataaa
     2521 ccatgacggt ttccccataa atatcttgat taaaatcaaa aatattgact tcaaaacgtg
     2581 cttcttctcc atcaaaggtc acatttttcc cgacactagc catagcacga tacttctgtc
     2641 tttgaatctc aacatcaacg acataaacgc catctgctgg catataagta cggtctaaaa
     2701 gcactaaatt cgctgtcgga taaccaattg tacgaccacg agcattacca tgaaccacca
     2761 tacctcttga tggaagcggt gcccccaaaa gttttcctgc ttctttcaca tttccatcta
     2821 aaatagcttg acggatacga gttgaactaa tctttccttt ctcatcttct acaggtggaa
     2881 caatgataac ttctccatca aagtaatcct ttaaatcttc tgctgttttt ttgtcagaac
     2941 caaatgtata atcaaaacct gcaacaataa ttttggcatt catagccttg atataagttg
     3001 caaagaattc ttgtgcagtg agactagcga attgactact aaaatcaagg agatataatt
     3061 cttctacacc ttcgcgcttt aattttcttt cacgttcagc agggttcaaa atatgcaaaa
     3121 acaaatctgg atgataaggc tctaaagcga tctttggaga ttcattaaag gtcataacga
     3181 cgataggcaa taaatccttt ctcgcagcct tgttggcaac acgaaataat tcttgatgcc
     3241 ccttatgtat gccatcaaaa tagccgagaa caacgactga atcagatggt gtgccaatat
     3301 ctttttggtt ttttatagga atagtaataa tcataaaata attatatcat agcgatagct
     3361 atttctggaa cagaaaatct gaaatgttgt ttttttcaca tgaagtgtac ctgttttcaa
     3421 aaggcacttt attctatcgt tgcttaacta tgaactttgc aatattcttc tcaaaaactt
     3481 gtaggacatc ttcaaaattt tgcaaggagt gattagactt gttcggtaac cataaagtgt
     3541 catactatgc ttatgtatga aaaagcaatg caactaactc ctgagaactt taaattacta
     3601 attggtgccg aaaaggtaga atttagaatc gaggtacacc tatggctgta aaatttacaa
     3661 aatgagacaa cttgggcaag atgtttgaag aatttcctaa actccctgat ttgaagcaag
     3721 tcactttccc tgatgacaaa gaaaaaagcc aaagcaataa agaaaaacta gatgactgct
     3781 ttccaacaac tcccatctag tgtgcttcag actgggctat ttttctttcc atctgttagc
     3841 ttggattctc agaccgtttc agctaaagaa tatcttttcc tttatcagaa ggaacggctc
     3901 aagccattca gacaagtgaa gggacgacaa gccaatattt gaaaccaggt agcagttctt
     3961 atagtcaatt gaaataaaat ctgaagaaat cgagtaggaa acttaaatca atttttagca
     4021 gtgttctatt ccagattcat actcaatgaa aattaaagtg caaactagga agttagccgc
     4081 aggctgtact tgagtacggc aaggtgaaac tgacgtggtt tgaatttgat tttcgaagag
     4141 tatcaatcca ctatacatat taaaaagtat gggtaccaaa acaaaaaaac aggctctccg
     4201 aaaactcgga aagccttatt ttaagctgtt tctagcttcc tcacctttac atttcaaggt
     4261 tcgggataaa aggttcaatg gaccttttta tttagcgatt gggtaaacag aaacttgttt
     4321 tttatcgcgt cctttacgtt caaagcgtac tacgccttca actttagcga acaaagtatc
     4381 gtctccacca cgaccaacgt ttacacctgg atagatgtgt gtaccacgtt gacggtaaag
     4441 gattgatcca cctgttacag tttgtccgtc agctgcttta gctccaagac gttttgcttg
     4501 tgaatcacgt ccgtttgatg tagaacctcc accttttttg tgggcgaaaa gttgcaagtt
     4561 gttaagagtc atttttaaca taatgttttc ctccgtgtta gttttctgtg ataactctgg
     4621 tttggacgaa ctcagaatag ttctccgata agtttgccat acctaagaaa aatgattcaa
     4681 agaataactg ggtcatttct ctctggtgtg aaggaagatc ttttggtatt tcaaccatca
     4741 gatagccacc ttcatcttcg tttaattcta ggattggttc atagcctgca aatttctcaa
     4801 tagaattgat aaagttaatg gcaagcgtag aaaccgatgc acacacgaca tctaagccgt
     4861 attcgccact ctcggcgtgt ccagtaattt ccgcactcct cagctcgcca tcttcggctc
     4921 tctcaaagac tgcttgtatc atgtgttctc cttaaaatta agcgttaatt gcgttgatga
     4981 caacttttgt atatggttga cggtgacctt gtttacggtg gctacctttt ttaggtttgt
     5041 acttgtaagt aacaactttc ttttgttttc cttgtttttc aacagttcca actacagtag
     5101 ctccagcaac aagtggagtt ccgacaacag tgttttcacc accaacaaga acaacttcgt
     5161 taaaagtaac ttcttgacca gcttcaacgt tcaatttttc aatgtaaact gcttgaccaa
     5221 cttcaacttt aacttgtttt ccgccagttt tgataattgc gtatgtgctc attatgcacc
     5281 tcctatgatt tttatgggtt tccccgattt tttgtgaaga ctcgcctagc atcgtgggac
     5341 aaaccactta aacttgaata atcaagcaac gatgttcgtg cggttgcaca ggatcgtgca
     5401 tagtcaactc ttcaagtata gcatatctcc tattttctta caagtaataa cacctaaaat
     5461 caagcttttt cttttacttt tttctgccac taggcaaaaa gcatactgag ataaaaaatg
     5521 ctcatcataa taggaacacc aagaatggtc ttttcatgat agaaaatcgt caaataggct
     5581 gaaaagacaa cgccaaggac aaaactacta agcaggctaa caaatatgaa cccttcacgc
     5641 aaaaaaggag tgtgcttagt tcggaaataa tctccaaaag ctagcattgt tcgtttgata
     5701 ttccctgtca taaaggcatt attgtaggca atacccgaaa cctcaccaaa agcagttgtc
     5761 accagtccca tacagaaggc caagggctgc actagataga tattatctac agtttgtggc
     5821 acaaaaccaa taattattga taggattgct aaaggaatca aggacagaat aggttttttc
     5881 acaattctca atttttcctt ataaatcgtt aataaaaaga ctcccattat aaacgttatt
     5941 aaggttaaaa gcttatccct aacatccgaa acattatttt gtattagctc taccgaaaga
     6001 aagacaacat ttccagcttg tccagctaca agggtattcc ctcgaacaat aaaagtgtaa
     6061 gcatccacat atccagcaca aaatgtcaaa aaagtgctaa ccttttagac tgacgtgata
     6121 tttttcttat aggtaataac ctcattttcc ctcccattgt attttctctt agaaatattg
     6181 taccatttct ttctaaaaaa tcgtagacta ccatttagat tttactatta gcataaaaat
     6241 aatagacaac tatttatcca aaaatagata gaggtaacat gtttgcaaac aaagcatacg
     6301 aacctttagt aaaatcattt ccatgaaact agaatagagc ccctcttagc aaaaatcatt
     6361 attttaattt atttctaatc actccttgac ataaataact ctcaccaata aaagactatg
     6421 tcttaaaaaa atggtataat aaaatcaata cttgggcttg atggctatgc tactaataac
     6481 aattaggaga gaaaatcagg cacttgttaa caacaaggat tatccccttg agatgaaagg
     6541 aactttagaa atcttatgat gaacatgcaa aacatgatgc gtcaagcaca aaaacttcaa
     6601 aaacaaatgg aacaaagcca agctgaactt gctgctatgc aatttgttgg caaatctgct
     6661 caagatcttg tccaagcgac cttaactggc gataagaaag ttgtcagcat tgatttcaat
     6721 ccagctgtcg ttgacccaga ggaccttgag actctttctg atatgaccgt tcaagccatc
     6781 aactctgctc ttgaacaaat cgatgaaact accaagaaaa aactgggtgc tttcgctggg
     6841 aaattacctt tctaaaaaca aggagctaga acaatgcttg tcgataacaa aggctaagaa
     6901 aggtgcaaaa atgactctat aatatttgta gtgggtaaat ccactataga tattatggag
     6961 cctattttat tgtagaaaaa aagtcccata agatctataa tgaaaagcga ccaaacaact
     7021 cattagaaag attcatatgg aacaattaca ttttatcaca aaattactag acattaaaga
     7081 ccctaatatc cagattttag acatcatcaa taaagataca cacaaggaaa tcatcgccaa
     7141 actggactac gacgccccat cttgccctta gtgcggaaat caattgaaga aatatgactt
     7201 tcaaaaacct tctaaaattc cttatcttga aacgactggt atgcctacta gaattctcct
     7261 tagaaagcgt cgtttcaagt gctatcattg ttctaaaatt atggtcgctg aaacttctat
     7321 cgtcaagaaa aatcaccaaa ttcctcgtat tatcaaccaa aaaattgcgc aaaagttgat
     7381 tgagaagatt tctatgaccg atattgctca tcagctggcc atttcaactt caactgtcat
     7441 tcgcaagctc aatgactttc actttgagca tgatttttct cggcttccaa agattatgtc
     7501 ttgggatgag tataccttca ctaagggaaa gatgagtttc attgcgcaag attttgataa
     7561 tcttaatatt atcactgttc ttgaaggcag aacacaagct gtcatccgaa atcactttct
     7621 taaatatgat agagccgtcc gatgtcgcgt caaaatcatt actatggata tgtttagccc
     7681 ttactatgac ttggctaaac agcttcgctt tcaaatttct aggctcaggc tgaaacagtc
     7741 tcccaggctg tttcactccc gaatgctaaa atcgttcttg atcgctttca cattgtacaa
     7801 catcttagcc gtgctatgag tcgtgtgcat gtccaaatca tgaatcagtt tcatcgaaaa
     7861 tcccatgaat acaaagctat caagcgctac tggaaactca ttcaacagga tagccgtaaa
     7921 ctgagtgata agcgatttta tcgtcctatt tttcgtatgc acttaaccaa taaagagatt
     7981 ttaaacaagc ttttgagcta ttcggaagac ttgaaacacc actatcagct cttgcttttt
     8041 cacttccaga ataaggaacc agagaaattt ttcgggctta ttgaggacaa tctaaagcag
     8101 gttcatcctc tttttcagac tgtctttaaa acctttctaa aggacaaaga gaaaatcgtc
     8161 aacgcccttc aactacccta ttcaaacgcc aaattggaag cgaccaataa tctcatcaaa
     8221 cttatcaaac gcaatgcctt tggttttcga aactttgaaa acttcaaaaa acggattttt
     8281 atcgctctga atatcaaaaa agaaaggaca aaatttgtcc tttctcgagc ttagcttttc
     8341 ttcaacccac tacagttgac aaagagccaa aaaattctct tttcatactc atttaaaatc
     8401 aaaaagggaa tttatcgttt tacggacatg tatattacag atttctatag gtcgtatata
     8461 gacaggatat tatcgcttag aagttgtcct ttttgacacc aatcagtaat ttagttctca
     8521 ggagttaatg gaagtgcttt tcgcacatag tttcataact acagtatagc atagtatatt
     8581 actttatagt tttcactatt gatgaactgc ttgagctgct gtgatgaggg tcaacttgta
     8641 aacatcatct gcattacatc cacgagaaag atcattaact ggcttgttta aaccttgcaa
     8701 aacaggtcct acagccgcaa agccacccag gcgttcagcc atcttgtaac cgatatttcc
     8761 tgcctcgata cctgggaaga tgaagacatt tgcttgacca gctactgtac ttcccggagc
     8821 tttcagagct gcagtttcgg gaacaaaggc cgcatcaaat tgcaactcac catcgatttc
     8881 aaggtcagga cgcaagtcgt gagcaatttt agttgcttca acgaccttat caacgctttc
     8941 accaaaccct gaacctttag tagaatagct caacatggca attttaggtt cgatgccaaa
     9001 catcttagct gtgattgctg agttgatggc aatttcagcc aaggcttctg catctggatt
     9061 gatattaatg gcacagtctc caaataggta acgttccgta ccacgaacca tgaggaaggc
     9121 tcctgaagta cgagttacat ttggacgagt tttgatgatt tgtagagctg ggcgaactgt
     9181 tgaagctgtt gagtgaatcg ctcctgacac cattccatca accaagccca agtaaaccaa
     9241 catcacacca aagtagttga catcttcaac caaaaccttg cgtacatctt cttcagtcat
     9301 tttgcccttg cgacgctcca ccaaggcaga aaccatttct tcaaattgag gataatgttg
     9361 agggtcgatg acctcataac catccatgat tccttcaatt tcaagataaa ttttaatttt
     9421 ttcaggattt ccaagcaaaa caggaatcac ttctgtttct tttactaagc gttttgttgc
     9481 ttgaagaata cgaggctctt ccccttcagg gagaacgata cgagcatttt taccaacaag
     9541 gttggctttg agactttcaa aaacttccat gagttttctc ctttaagata ataattatac
     9601 tctgagacag tttttataga gtattagttg ataactgggt aataaggtta ctgaaatcat
     9661 ccggcaaggg actttctaac tgcaagtctt gctctaaaaa tggatgatta aaggataggt
     9721 aatggcaatg cagagcctga cgttgaatac catcttccag actaccacca tacaaatcat
     9781 ctcccagcaa aggaaaaccg atatgagaaa aatggactcg gatttgatgg gttcgaccag
     9841 tgtgcaggtg aatatagacc aagtgaatat ttccataaga agctacaatc ttgtatgaag
     9901 tatgggcata ctttccgcct ttagccactc gtctggtaat aatggaatct tcatcacgcg
     9961 caatcggagc aataatttcc ccttctggct ccaaatgtcc atctccctta accaaagcaa
    10021 agtagcgttt ctcgatagat ttcttctgca actgcttgtc taatcgtgca tgggcataac
    10081 cgtgcttggc aaagagcatc aagccagaag tgtccctatc tagtctggta acaatgtgaa
    10141 cctgctgatt ttcataattt tgcttgacat agtaaccctt gataaaattg gcaatggtat
    10201 tagagtgatt gacactagga atagaagcca ctccataggg tttattcaag actagaaagt
    10261 ggtcatcctc atagagaata tctaatggat gctcaatagc ctccaaggtt tcaaagcctt
    10321 cctcagcggg aatgtaaatg gtaacgtagt ctccaacgtc caatagatac gttgcatttt
    10381 gcggttgatt attgaccaga atagctccac ctcgaaactt aatcttggcc agcaatccct
    10441 tagaaacctc gtgctttttt aaaaaggtct taaccttgac atgttcatct gcgataaatt
    10501 caaacctcat tcatccacct caccgataaa ggcatcctta acacggttcc agaaactggt
    10561 atggctagga gtcgcgacaa agtgaatctt atgatggtcg atttgatact caatacgctc
    10621 aatattacgg aaagaataaa cgctattgtc aaccgaaata gtatgataat cgtttcttgt
    10681 tggaataagt tcaatcttat ccttcttagg cacaataatg gaagagccca atgttcgata
    10741 gacacgatta ttaaggctgg caatctccgt taattgcaaa gcttcaatgg tagggtgtaa
    10801 aacagcaccg ccaagagact tgttataggc agtactacca gtcggtgtcg aaactgttag
    10861 cccgtctcca cgaaaacgtt caaagggaac accatttatt acaatatctg ccaccatggt
    10921 tcgatcagac ctgcggatgc tggcttcgtt gagtgctctg aaaatcttaa cttcaccatt
    10981 ttcgagaaag accttcacat tcagaacagg gtaagaaacc cttgccccag tatctagctg
    11041 caaattagtc actagcttgt ccaactcaaa atcacgataa tctgtataga agcccaaatg
    11101 tccagtatga agaccgataa agcggacctt gtcaagctga ttttcgtact tatgaaaggc
    11161 cgacaagagc ataccatccc cgccaatgga aatgacaata tccggattgg tatcattgag
    11221 tataaactga tttctcttca aacgatttcg caattcatac aaaacccttt gactctgcgg
    11281 ttttctattg gctatcagat caattcgttt acctgtattc ttcatctgta tcgtcactgt
    11341 ttcctacacc gtcatttaat tttctactca aaggatcaaa aagtgcctgg gcttcttgga
    11401 tatcatcacg aatttcaccc atttcttcat ccaactgatg ggcgattcta gctgtaattt
    11461 ccagtcgctt cttaatctca tctgggaaat ccccttggta cttgtagttg agagaatgtt
    11521 ctatcgttgc ccagaaattc atggccaaag tacgaatttg aatttctgcc aaaatagtct
    11581 tagctccatt gatggtatca accgtatatt ctactaccac atgataggaa cgatagcctg
    11641 atgcttttct atgagtaatg taatctcgct cctgtatgat tcgcatatcc tgacgcttgt
    11701 gcaaaatatc cactacttcc ttgacgtcat ctacaaactg aaccatcaca cgtaagccag
    11761 caatatcctg caaatcgtgt tccaaggtcg cataagtaat gccacgacga gccatttttt
    11821 ctttgatgct ctcaattggc ttgactcgac cggtcacaaa ctcaattgga gaatgcttat
    11881 tttgcttacg atattgctta cgaataccac gaagtttaat ctttaactca ccaacagctt
    11941 gaatgtaagg atctagaaat tcttcccatt ctaaggtcat atattctccc ttgttctcat
    12001 attatccgtc aaaaatatct ttgatttttt ctccagattc atatacaata aatacaatgc
    12061 ttattatacc ataaatccgc tttcaacgat aaaaaaaggt aagaaaaatg aaacatttag
    12121 aaattgaatt gaaaacacta ttgaaaaaag atgaatacaa tcgtctaaaa gaccagttca
    12181 caggtgtcac tcctgttctt caaacaaatt actacatcga cacgcctgat tttgaactgc
    12241 gagaaaagaa agtcgctatg cgcattcgaa cctttgaaga ctgggctgag ttgacactca
    12301 aagtcccgca gagtgttgga aacatggaat acaaccaaaa attgcaacta aaagatgctg
    12361 agaactatct gagtaaggaa gaacttcctc aagggctagt actggatgaa ttggcgaaac
    12421 atggtatcca aagtaagaac tggcaggttc ttggttgtct aacaacgctt cgctatgaaa
    12481 tgaaaacagc tattggtctc atggcactgg atcagagccg atactttgat ataacagatt
    12541 acgaattgga gcttgaagtg gaaaatcatg agcaaggcaa acaggatttc cgacaatttt
    12601 tagagaaaaa tcagatttcc taccaaaaag ctccttcaaa attggttcga tttgtcaaaa
    12661 gtatgaaaaa tagctgaaat aatctccatt ttttggtaaa atagaaaaga taaaaataca
    12721 caaatcccag ttcatatatg taaggtaaat ataactagga tttataaagt ttacagagga
    12781 cggtctataa tgtcagatag aaaaaacatg aaacttttcg cactcaactc taaccaagag
    12841 attgcacaaa aaattgccca agctgttggt gtcccacttg gaaaactatc atcacgtcaa
    12901 ttttcagacg gagaaatcca agtaaatatc gaagaaagtg tccgtggtta tgatgtttac
    12961 atcatccaat caacaagttt ccctgtcaac aaccacctaa tggaattgtt aatcatggtc
    13021 gatgcttgtg tgcgtgcaag tgcccacagt atcaacgttg tccttccata ttttggctat
    13081 gcacgtcaag accgcattgc ttgtcctcgt gagccactta cagcaaaact agttgccaat
    13141 atgctggtta aggctggagt tgatcgtatc ctgactcttg atttgcatgc cgttcaggtt
    13201 caaggtttct ttgatattcc agtggataat cttttcactg ttcccctatt cgcaaaacat
    13261 tactgcgata aaggattgct tggttcagat gttgttgtcg ttagccctaa aaattcaggt
    13321 gtcaaacgtg cgcgtagcct ggctgaatat cttgatgctc ctatcgccat tatcgactac
    13381 cctcaagacg atgcaactcg taacgaaggt tatattattg gtgatgttga aggtaagaaa
    13441 gctatcttga ttgatgatat tttaaataca ggacgtacct tctctgaagc ttctaaaatc
    13501 gttgaacgtg aaggagctac agaaatttat gctgtttcta gccacggtct cttcgtcgag
    13561 ggagctgctg agcttcttga caatactaat attaaagaaa ttcttgtgac tgattcagta
    13621 gcaacaaaag aaaaaactcc taaaaatgta tgctacatca ctgctagtga gttaattggt
    13681 gatgctatcg tccgtattca cgaaagaaaa ccagtcagcc cactctttgc ctacaataaa
    13741 aagaaataag gtgattcttt gatttatttg gacaatgctg caacgactcc tatgtcagca
    13801 gttgctattt cagctatgac caaggttatg caagaaaccc acggaaatcc ttctagtatt
    13861 catggtcatg gtcgtcaagc tggcaaactc ttgcgagaag cccgtcagga actagcccag
    13921 ttactaagga caaaacctca acatatcttt ttcacttctg gtgggactga aggcaataat
    13981 actaccatca ttggctactg tcttcgtcac caagaacaag gaaaacatat catcacaact
    14041 gccatcgagc accatgctgt ccttgaaaca attgattact tggttcaaca ctttgggttt
    14101 gaagcaacca ttatccagcc agaaaatcaa gaaatcacag cccagcaaat tcaaaaggct
    14161 ttacgtgacg atacgatttt ggtttctact atgtttgcca ataatgagac aggaaaccta
    14221 cttcccatcg ctgaaattgg ccaaatactc aagcaacacc ctgctgccta tcatgttgat
    14281 gcagttcagg ctattggtaa aatcccaatt cattcagaag aattgggcat tgattttctc
    14341 actgcttctg cccacaaatt ccatggtcct aagggaatcg gttttctcta cgcatctagc
    14401 atggactttg attcctatct acatggcgga gatcaggaac agaaaaaacg tgcaggaact
    14461 gaaaatctgc ctgccatcgt aggcatggtt gcagccctaa aagaagacct agaaaaacaa
    14521 gaagaacatt ttcaacatgt acaaaatcta gaaactgcct ttctggcaga actggagggc
    14581 attcagtatt acttgaatag aggaaaacat catctccctt atgttctcaa tattggattt
    14641 cctggtcaga aaaatgacct cttactcctt cggctagatt tagctggaat ttcaatctct
    14701 actggctcag cctgtactgc aggcgttgtc caatccagcc atgttcttaa agccatgtat
    14761 ggcgcaaatt cagaacgctt gaaggaatcc cttcgcatca gtttgtcgcc acaaaatacc
    14821 gttgaagacc tacaaaccct cgcaaaaacc ttaaaagaaa ttatcggagg ttagccatat
    14881 ggcatttgaa aaaatcattc agttaaaaaa ttgtcgttac gattacactc ttagcccttc
    14941 tgttaaaaaa ttcaccctca aagataacac cttttttgaa actaaggttg gtaactatga
    15001 actgactcgc cttttggaaa aagtgccaaa cagcggtgaa ggcttccaac tcaaaatcat
    15061 cattaacaag gaacttacag gggctaaaat caatatcact gacaagtttg gccttcgtct
    15121 agttgatatt ttcaaatcag aagaccacca tattcatcag gaaaaattct acttcctcat
    15181 ggatagcttg gtagaacgtg gtgtctttac aaaatcggaa agatagagcc aaaatgtttg
    15241 aactgaccta taaggactgc tatcatgtag agcgtactct caagtatgag gatcatgagg
    15301 ctctcatgtt gactttgtca ggatgtgtaa ccttaccaga tacactttat gtgacttctc
    15361 tgacttttag gggcaaaaaa gtttatcagg ggctggtcgg agacctctac cgttttctat
    15421 ctcatgcaga ttttttacat caaaactaag atttttctta gttttttctt atttttgttg
    15481 attttttcac aatgtttcta taaaatagaa gaatagaaag gttgtgattt tgtgaaagat
    15541 aaacagtttg ctattccaaa agctacagca aaaagactct ctctctacta tcgaattttt
    15601 aagagatttc atgcagaaaa gattgaacgt gccaactcta agcaaattgc agaggctatc
    15661 ggtattgatt cagcgaccgt acgtcgtgat ttttcctatt ttggtgaact tggtcgtcgt
    15721 ggttttggct atgatgtcaa aaaactaatg acattttttg ccgatttgct caatgacaac
    15781 tctattacca atgtcatgct ggttggtatt ggaaatatgg gccatgccct tctccactac
    15841 cgcttccacg aacgtaacaa gatgaagatt atcatggcct ttgacctaga cgaccatcct
    15901 gaagtcggta cccaaactcc tgacgggatt cccatttacg ggatttctca gatcaaggat
    15961 aaaatcaagg atgctgatgt gaagactgct atcctaactg ttcccagcgt caagtcacaa
    16021 gaggttgcta atctcttggt tgatgctggt gtgaaaggaa ttctcagttt ttcaccagtc
    16081 catctgcatt taccaaaaga cgtggtcgtt cagtatgtcg atttgacaag tgaactccaa
    16141 accctcctct acttcatgcg aaaagaggat tagaaagcga aaatcatttt atgaaaaaac
    16201 cagttattgg gattacagga aacgaaaaag ctcatccaga tgatgacatc atgatgagct
    16261 acgcagcaaa aggctttgtt gaaggcgtta aagatactgg agggattccc atcatcctac
    16321 cgattggtga tcaagaaatg gcctgccact atatcagttt gattgacaag ctcatcttga
    16381 caggtgggca aaatgtcgat ccaaaattct atggcgaacc caaaaccatt gatagcgatg
    16441 actatcacct tcaaagagat atcttcgaac tggccctcat caaggaagct attaaacaga
    16501 aaaagcccat tttctctgtc tgccgtggta cccaactctt taacgttgcc atgggtggaa
    16561 ctttgtacca agatatcgaa gaccattggc aggattcttc tgttgagtac acaactcaac
    16621 gcttggtaac agaaccagat accgttctcc aagaaatcta tggagaaatc tctcatatca
    16681 actccttcca ccaccagagc atcaaggact tagcaccaaa tttaaaagtt gtggctcatg
    16741 atcctaaaga tggtatcatt gaggctgtca tgagtacgga tgatgtcgcc tttctcggtg
    16801 tccaatggca tccagaactt ctttttgaaa atcgtcccaa agataagaaa ctctttgact
    16861 atgtcgttaa tgaactttag attaaatctg tcttttcacg ataactaaag taattagaat
    16921 gagagacaat caaatggtcc aagagaacaa tccccatcag ttcgcaggct tctttaacaa
    16981 gtttagtgac atgatcatca ttttggctag gcgctaccgc tcctgaagga tgattgtgga
    17041 ccaagataag agaagtcgcc atatgcttga ttgcatagtg cagaatctct cgcggttcag
    17101 cgatactacg agttacagac ccgataaaaa tggtctgctg atggatgatt tgattttgag
    17161 tattgagata gagtgccacc aggtgctctt gttttttatc ccctaattcc tgctgcatct
    17221 tcttggccaa cttttgactg ctgagaatac tttccatttc aagagtctcg tgtttgtgaa
    17281 tacgatgccc cagttcaatc atagcttgta attctatggc cttaacacgc ccaataccag
    17341 acaaactctg caattcctgc agggtcattt ttttcaaatc cgttaggctt gaaagattgt
    17401 tcaagacttt ttgggcaatt tcaaaaacgc tagcttgacg tgttcctgtc ctgagtaaaa
    17461 tagctagcaa ctcttggtta ctaagcgctt caactccttc cttggccagc ctttctcttg
    17521 gtaatagtga atcttcttgg aatgaaatac tgtacataaa aatcctcctc actttattat
    17581 tcgtgagaag gatggaaaat tagatttttt tctcaattgg agccacactg gctaaaagtt
    17641 ttttcaaacc tacttctggg aaattgattt tcaattcctg cctagcaccg ctacctgaaa
    17701 cttccagaac agttccctct ccccatttct tgtggagagc aatgtcacca atggaccaat
    17761 ttgcctcgct agatgctgat tttgcgccag ctgtaaattg accaaatgga agaccgcttg
    17821 actggattga ttttggggca gcaccgcgtt tacggtcttg aagagcctga gccaaactca
    17881 taccttgacc aaaggaaata ctaccactgc tatatgatgc cttaaagctt gtatttgcag
    17941 gacgagccag accttgatac tcaagcaagt ctgaactgat ttcgttaata aaacgagtcg
    18001 gacggttata attggtacga ccaaaaagca agcgtgagtt ggcattggtc agatagagaa
    18061 ttttctctgc acgcgtgata cctacatagg ctagacggcg ctcttcttct aattcatctg
    18121 gatcttcagt cgcacgacta agtggaaaga cattttcttc catcccaatc aaaaagacaa
    18181 ctggaaattc gagacctttg gcagcatgca gggtcatcaa ggtcacttct gatgtctcct
    18241 gactacctga atctgtgtcg gcaatcaaag ccaagtcatt taagaaacga ctcagtttgt
    18301 ccagaccagt ttcctcttct gtcacatcag tggtgtcatc aaagttcttc gtaacagaaa
    18361 gaaactcttc gatattttca acccgtgcct tgctttctag agtcgcttgg gcgttaagaa
    18421 tatcgacata acctgttttt tctaggacgg actcaaccaa ctctgtaatg cttaagtggt
    18481 ctagctgctc ccgcaaatca agcatcatat tggcaaaatc ccagatagat tgggctgcct
    18541 tacccttgat accagacaac ataatattag cagaagcatc cagcatagac atattttgca
    18601 aatttgcaaa atcacggatt ttctcaactg tacctagacc aattccacgt ttaggctcgt
    18661 tgataatacg ctcaaaacta atattgtcac tcaaattagc aataaggttg agataagcaa
    18721 taatatcgcg aatttcctta cggctgtaga atttggttcc gccaaccatg gtataaggaa
    18781 tgttagactt gagcagggct tcctcaattg tacgggactg ggcattagtc cgatagagaa
    18841 ctgcaaaatc cttatgaagg aagttttgac tgcgactaag ttcatcgatg gttctggcta
    18901 caaatacagc ctcatccagc tcatcatcgg cacgatagta aacgatttgc tccccatcag
    18961 cgttttgagt ccagagattt ttaggacggc gatttttatt atttttaata acctcgttgg
    19021 ccgcttggag aatggttttg gttgagcggt aattttcctc caacaaaaca accttggctt
    19081 tggggtaatc cttttcaaag tccaagatat tctgcatatc agcaccacgc caaccgtaga
    19141 tagactggtc cgcatcccca accacacaga tatttttaaa acgggaagcc aagagtttga
    19201 ccaattggta ctgagcatgg ttggtatctt ggtactcatc aacgtggatg tattggaatt
    19261 tttgctggta gtaggtcaaa acatcaggat tttgatcaaa gagacgcaag gtcagcataa
    19321 tcaaatcatc aaagtcaacg gattcagact gacgaagttc tttttgatag gctgtataac
    19381 actgggccac aatttgcgta tacatatcgc cagcttgggc agcataagca acatcatcaa
    19441 tcaaatcatt cttagcattg gaaatggtcc ccaaaatagt tcgttcattc cattttttag
    19501 gatccaagtt caactgtttg agaatacgtt tcatgagcgt tcgctgttca ccaggatcca
    19561 caattgtaaa attacgattg tagccaatat ggtccgcatc gcgacgcaaa atacgcacac
    19621 acatggagtg gaaggtcgca atcagacagt cctgagtagc tggattgagg ctataagcac
    19681 gctctttcat ctcacgcgca gccttgttgg taaaggtaat ggccaagata ttccaaggat
    19741 tgaccagctt ttcatcaatc aaataagcga tacggtgggt taaaacacga gtctttccag
    19801 aaccagcccc tgccatgatt agcaagggac cttctgtcgt ttgcaccgcc tcagcctgac
    19861 ggtcattcat tccatttaat aatgcgttca tcttctcttc cttactcttg aagtcaatat
    19921 ttctattata tcagaaatca gggaaaatag aaactttacg gggagtagca aaatatagtg
    19981 gattgaaact agaatactac actgtgggtt tctaaaacac tcgacttttc acccaatttt
    20041 ttcataaact agctcaatac ctcaatagac ttcctgcaaa actagaatcc tagttcatga
    20101 ttgataatac cagcaatcaa attcattcgt aatccgaagc gtttacgatg atttcgatag
    20161 gttgttgaaa acattttaaa cgtttttact ttggcaaaga tattctcaac cttgcttctc
    20221 tccttggata gcgcatggtt ataagcttta tcttcaactg ttagcggctt gagtttgctg
    20281 gatttacgtg gagtttgtgc ttgagg
//
LOCUS       DAVLGK010000040        19529 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLGK010000040 DAVLGK010000000
VERSION     DAVLGK010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.040"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..1233
                     /locus_tag="VXE01_001638"
     CDS             <1..1233
                     /locus_tag="VXE01_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0750509.1"
                     /translation="SSSGTADLYITEVDLYKGYKPRTWQPHPEDAVADANKKLEATQT
                     KMTQLAGSWVVENINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMVD
                     KLKTGNFEAGSVTTTILDAEAVTAEKLKVDDALIRKLTANDAFIDQLISKRIFSIKVE
                     SVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAGYGVRTAFWANW
                     GNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGI
                     ELGSKDVLGDGWNPKGGRNAVVWWNQVGSGSLKYWMEQKSDRRLKENITDTAVKALDK
                     INRLRMVAFDFIENKKHEEIGLIAQEAETIVPKIVSRDPENPDGYLHIDYTALVPYLI
                     KAIQELNQKIEKMEKTIA"
     gene            1327..1530
                     /locus_tag="VXE01_001639"
     CDS             1327..1530
                     /locus_tag="VXE01_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750510.1"
                     /translation="MNTEQLNQALQMTIREISTTSTNSMIESNILSIQLDEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            1533..1883
                     /locus_tag="VXE01_001640"
     CDS             1533..1883
                     /locus_tag="VXE01_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750511.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            1892..2191
                     /locus_tag="VXE01_001641"
     CDS             1892..2191
                     /locus_tag="VXE01_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750512.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHTVGDIQKEMVRMNDRMEEIEKGE"
     gene            2195..2527
                     /locus_tag="VXE01_001642"
     CDS             2195..2527
                     /locus_tag="VXE01_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0750513.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRAAKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVASETGFKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            2531..3487
                     /locus_tag="VXE01_001643"
     CDS             2531..3487
                     /locus_tag="VXE01_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0750514.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLAD
                     RWKKHTDGNWYYFDQSGEMATGWKKIADKWYYFDVEGAMQTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTMADKPEFTVEPDGLITVK"
     gene            complement(3625..3804)
                     /locus_tag="VXE01_001644"
     CDS             complement(3625..3804)
                     /locus_tag="VXE01_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750515.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(3946..4095)
                     /locus_tag="VXE01_001645"
     CDS             complement(3946..4095)
                     /locus_tag="VXE01_001645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750516.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            4376..4843
                     /locus_tag="VXE01_001646"
     CDS             4376..4843
                     /locus_tag="VXE01_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV0750517.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            4876..4972
                     /gene="ffs"
                     /locus_tag="VXE01_001647"
     ncRNA           4876..4972
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VXE01_001647"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            5029..5472
                     /locus_tag="VXE01_001648"
     CDS             5029..5472
                     /locus_tag="VXE01_001648"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV0750518.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            5474..5989
                     /locus_tag="VXE01_001649"
     CDS             5474..5989
                     /locus_tag="VXE01_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0750519.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGFPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            6003..7364
                     /gene="radA"
                     /locus_tag="VXE01_001650"
     CDS             6003..7364
                     /gene="radA"
                     /locus_tag="VXE01_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV0750520.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSININRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            7437..7934
                     /locus_tag="VXE01_001651"
     CDS             7437..7934
                     /locus_tag="VXE01_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV0750521.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            7959..8739
                     /locus_tag="VXE01_001652"
                     /pseudo
     CDS             7959..8739
                     /locus_tag="VXE01_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            8884..9852
                     /locus_tag="VXE01_001653"
     CDS             8884..9852
                     /locus_tag="VXE01_001653"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0750522.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(9986..10267)
                     /locus_tag="VXE01_001654"
                     /pseudo
     CDS             complement(9986..10267)
                     /locus_tag="VXE01_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(10394..10627)
                     /locus_tag="VXE01_001655"
     CDS             complement(10394..10627)
                     /locus_tag="VXE01_001655"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750523.1"
                     /translation="MFSQLHMREEQVLLAQDYPLETARAEGLEQGLERGKVEGREERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            complement(10620..10736)
                     /locus_tag="VXE01_001656"
                     /pseudo
     CDS             complement(10620..10736)
                     /locus_tag="VXE01_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            complement(10951..11301)
                     /locus_tag="VXE01_001657"
     CDS             complement(10951..11301)
                     /locus_tag="VXE01_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0750524.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            11557..14190
                     /gene="polA"
                     /locus_tag="VXE01_001658"
     CDS             11557..14190
                     /gene="polA"
                     /locus_tag="VXE01_001658"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV0750525.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            14275..14712
                     /locus_tag="VXE01_001659"
     CDS             14275..14712
                     /locus_tag="VXE01_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV0750526.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKTAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            14753..14830
                     /locus_tag="VXE01_001660"
                     /pseudo
     CDS             14753..14830
                     /locus_tag="VXE01_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(14985..15995)
                     /locus_tag="VXE01_001661"
     CDS             complement(14985..15995)
                     /locus_tag="VXE01_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV0750527.1"
                     /translation="MSFLSKNGAGILVCLLISILSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSHKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            16144..17313
                     /locus_tag="VXE01_001662"
     CDS             16144..17313
                     /locus_tag="VXE01_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0750528.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            17310..18080
                     /gene="recO"
                     /locus_tag="VXE01_001663"
     CDS             17310..18080
                     /gene="recO"
                     /locus_tag="VXE01_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV0750529.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            18077..19069
                     /gene="plsX"
                     /locus_tag="VXE01_001664"
     CDS             18077..19069
                     /gene="plsX"
                     /locus_tag="VXE01_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV0750530.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            19075..19308
                     /locus_tag="VXE01_001665"
     CDS             19075..19308
                     /locus_tag="VXE01_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0750531.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            19354..19529
                     /locus_tag="VXE01_001666"
                     /pseudo
     CDS             19354..19529
                     /locus_tag="VXE01_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5617 a         3554 c         4770 g         5588 t
ORIGIN      
        1 tcatcatcag gaacagctga tttgtatatt acagaagttg acttgtacaa aggttataaa
       61 cctagaacat ggcaaccaca tccagaagat gcagtcgcag atgcgaataa gaagcttgaa
      121 gccacgcaaa caaaaatgac tcaactagct ggctcatggg tagttgaaaa catcaactcg
      181 gctggagata tcatctctgg aatcaatctt ggcgccaatg gacataaccg ctttgttggg
      241 aaattgaccc acatcactgg agagaccctg attgacagag cagtcatcaa gtctgccatg
      301 gttgataagc tgaaaacggg caattttgaa gctggttcgg tcacgactac gatattagac
      361 gctgaagcgg taactgctga gaagttgaaa gttgacgatg cgcttattag aaaattaact
      421 gcaaatgatg cttttattga ccaactgata tctaaacgta tcttctctat taaggttgag
      481 tccgtcattt ctagctcaac cttcctagaa gcctatcaag gccgaatcgg tggattcaca
      541 cttggtcaat ttgaccaggg tggcggtcgc tggatttcag gtgtcaatca gttctctgtt
      601 ggtatgggga atggtgccgg gtatggagtc cggacagcct tctgggcgaa ctggggaaat
      661 aattggaact atgccggacc taaagcatgg aacgtcaata ctgatgggaa aatgtactgt
      721 aggaatgaag tcggttttta tgatcaagtg gatttttcga attcatcgag agcaaacttc
      781 tatgggaata ctactttttc tcgttctcct gtgttttcaa atggtatcga acttggaagt
      841 aaagatgtgc ttggtgatgg ttggaatccc aaaggcggaa ggaatgcggt tgtttggtgg
      901 aatcaggtcg gtagcggtag cttgaagtat tggatggaac aaaaatcaga tagacgctta
      961 aaagagaaca tcacagatac agctgtgaaa gccttggata aaatcaacag attaagaatg
     1021 gttgcatttg atttcatcga aaataagaaa catgaggaga ttggtctaat agctcaagag
     1081 gctgaaacca tcgttccaaa aattgtctca cgagatcctg agaatccaga tggctatctg
     1141 catatagact ataccgcttt agttccttac ttaatcaagg ctattcaaga attaaatcaa
     1201 aaaatagaaa aaatggagaa aacaatagca tgaataacaa catgttgacc aatatcgcac
     1261 ttaaagcaat tcaggagttt gctcttgaaa atagaaaacg aacacacaga ttggagaact
     1321 tagaaaatga acacagaaca gcttaaccaa gccttacaaa tgacaattcg tgaaatatca
     1381 acaacttcaa caaattcgat gattgaaagt aatatcttga gtattcagtt ggatgagcaa
     1441 agggaagaga atcaaagact tcaagcacga gtggatgagc tggaagctct gcttgatgaa
     1501 caaactaaac cagctgacaa aggagaatag acatggcaga aacaattcaa aacacagata
     1561 acttactaga ccttacaaaa atcacagaac catttgatct tgcgagcgct ttgcgctata
     1621 tgaaagaaaa tggagagttc attcgttgca agaatgtaag cgatgacttc tatatgtatc
     1681 gtgatgttca aaaacgtcct gtgatcgtaa atggccgtcg ccaactcaag gatgttgaaa
     1741 ccgtttgggc gttcaaccag tggggtggta caatcgcaac aatcaacgtc gccgttctgt
     1801 tgaatcatga attctatatc atgaaatttg atgcagaggg caatcctgac tggacggttc
     1861 caacggtaga acctaaagaa taggaggttg tatgccaatt gaagaagctg aaaaaatcgc
     1921 tcaaagtcag gtagcttggg cgattttgtt tatcttgctt ttttttatta tcattcgata
     1981 tcttatcaag acttcggaca agcgagagaa gaagattatg gatttgcacg agcaatcaaa
     2041 ggccgactct aatagacgag aagagcgttt gatgactcac ctagaaaaga ccactacaga
     2101 attaaccaca atcactcaca cggtcggaga cattcaaaaa gaaatggttc gcatgaacga
     2161 ccgcatggaa gaaatcgaaa aaggagaata acaaatgcaa caaattactg aaatcattac
     2221 taatggagca atcagcatcc tagtcatttt ggcaggggtg gtagttaggg cagccaagga
     2281 atacctcgtc aaaaaaggtg gagaaaagac tatcaagatt gttgaaatct tggccaagaa
     2341 cgcagtaaat gccgttgagc aggttgcctc agagactggc tttaaaggcg atgaaaaact
     2401 ggcacaggct cgcgctaaag tccgtgctga gcttacaaaa tacaatatta gcatgactga
     2461 caaagactta gacaccttcg tagagtcagc agtgaagcag atgaatgacg catggaaagg
     2521 acgataggga atggatatcg atagaaacag actacgaaca ggcttgccac aggttggggt
     2581 gcagccttat cgacaagtac atgctcactc aacaggcaac cgtaactcaa ccgctcaaaa
     2641 tgaagctgat taccactata gaaaggaccc tgaactaggg ttcttttcac atgttgtcgg
     2701 aaacggccgt gtcatgcaag taggacctgt gaacaacgga agttgggatg ttgggggcgg
     2761 ttggaatgct gagacctatg cagcggttga actgattgaa agccattcaa ctaaggaaga
     2821 gtttatggct gactatcgcc tttatatcga attgctacgc aatctagcgg acgaagcagg
     2881 cttgccgaag actcttgata cagacgactt ggcaggtatc aagacgcatg aatactgtac
     2941 caataaccaa ccaaacaacc actcagacca tgtggatcca tatccatatc ttgctaaatg
     3001 gggcattagc cgtgaacagt ttaagcaaga catcgaaaac ggcttgagcg ctgcaacagg
     3061 ctggcagaaa aatggcactg gctactggta cgtacactca gacggctctt atccaaaaga
     3121 taagtttgag aaaatcaacg gtacctggta ttatttcgat ggctcaggct atatgcttgc
     3181 agaccgctgg aagaagcaca cagacggtaa ttggtactac tttgaccaat caggcgaaat
     3241 ggccacaggc tggaagaaaa tcgctgacaa gtggtactat ttcgacgtag aaggtgctat
     3301 gcaaacaggt tgggtcaagt acaaggacac ttggtactac ttagacgcta aagaaggtgc
     3361 tatggtatca aatgccttta tccagtcagc ggacggaaca ggctggtact acctcaaacc
     3421 agacggaacg atggcagata aaccagagtt cacagtagag ccagatggct tgattacagt
     3481 taaataaata gaaaggaaac tttctaaatt gttctttcac cgcaggctca ggcttgcggt
     3541 tttttatttg ctctgatttt tcaaaaaagt gcttacttga agaataggga ggtgttttgt
     3601 caaaaataaa aacagtgacc gaaatcactg cttatcagtt gtagcaaatt cataaagttt
     3661 ttctgctgtg agaagtgcca ttttgtccat gcttgttttt ccttttctga ggtcagaaac
     3721 agtagtccat ggaactccag caccttggga aatagcagat gtagacatcg aactgtctaa
     3781 caattcttga ataacttctc tcatcttatt tgtccttttt attttttaga taaatatata
     3841 cattgattgc aattataaaa atagctattg cactaaccat tgcatttcct ctttccattt
     3901 gataaaatag aggtgtaagg ggctttcgcc ccaacctctt agcgtttacc tttttctttg
     3961 acgggatttc ggtttacgct ttttgttttg ccttgcgacc gttattgcgg tcactagact
     4021 tgcgatagca gttaccgttt caggaatatt gtctattgcc ttttcaagta acctgagcca
     4081 atcttctttg ttcaacttca tcaccccctt tccttatctt gattatatta tatcacggta
     4141 caccgagaaa gtcaagcgtt ttgatgaagt ttttttaatt ttttcaaaaa aaaatagacc
     4201 ttgtccagag gtcggggagt tggagggggc accctccaaa agcattgatt taataaggtt
     4261 ttattttacc tttttcataa taatctccct atagagtcac cgcattcggt ggcttttttt
     4321 gtgttgggat tcatgatata ataataaaat cgataagtag gaaaagagaa aagagatgta
     4381 ttatacgctt gaagaaaaag aagtctttat gagggaggct ttgagagagg ctgagattgc
     4441 tcttgaacac gatgaaattc caattggttg tgtgattgtc aaagatgggg aaatcattgg
     4501 tcgtgggcat aatgcgcgtg aggaattaca gcgagcggtt atgcatgcgg aaattatggc
     4561 tatagaggat gcgaacttga gtgaggagag ctggcgcttg ctggattgca cactttttgt
     4621 gaccattgaa ccttgtgtca tgtgtagtgg agcgattggg cttgcccgca ttccaaatgt
     4681 ggtctatggg gctaaaaacc agaaatttgg cgctgctggg agtttgtaca atatcttgac
     4741 agatgagcgt ctcaatcatc gtgtggaggt tgaaatagga attttggaag atgaatgcgc
     4801 agctatcatg caggattttt ttagaaatag acggaaaaaa taattttgct tttaaaatga
     4861 ataggaatgt gatataataa atagtggagc aacagttctg cgtgaagcgg gtcaggggag
     4921 gaatccagca gccctaagcg atttgaattg tgtgctcttt ttttgtgctt tttccgaata
     4981 aataagatag aataatctag aataaatgat aatagaaaag agaaaattat gaaaattcgt
     5041 ggttttgaat tggtttcgag ttttacagat gaaaatttat tgcccaagcg tgagacagcg
     5101 catgcggctg gttacgactt aaaggttgct gtgcgtacag ttgttgcgcc aggagagatt
     5161 gtcttggttc cgacaggggt taaggcttat atgcagccga ctgaggttct ctacctctat
     5221 gatcgttctt caaatcctcg taagaagggc ttggttttaa ttaactcagt tggggtcatt
     5281 gatggggatt attatggaaa tcctggaaat gaagggcata tttttgcgca gatgaagaat
     5341 atcacagacc aagaggttgt tcttgaagtt ggggagcgta ttgtccaggc tgtttttgct
     5401 actttcttaa ttgcagatgg agatgcggct gatggcgttc gaactggtgg atttggatcg
     5461 acagggcact agaatgaaga ttatctttgt acgtcatggg gagccagatt accgtgagtt
     5521 agaggagcgt tcttatatag gatttgggat agatttggca cccttgtctg agatgggacg
     5581 gcagcaagtc cagaaattga gcaaaaatcc tttactctcg tcagctgaaa taatcgtatc
     5641 ttctgcagtc acaagagctt tagaaacggc ttcgtatgtg gtctgtgcta cgggttttcc
     5701 tttaagagta gagcctttat tacatgaatg gcaggtctat aaaacaggaa tagaaaactt
     5761 tgaaacagct agaagactgt ttttagaaaa caagggggag ttgcttccta atagtcctat
     5821 tcaatatgag acagctacgg aaatgaagtc tcggtttcta gaatgtatgt ctaagtatcg
     5881 agaacatcag actgtggtag ttgttgctca tcgaatgctc atgcgccagt ttgtgccaaa
     5941 tgagaagatt gatttttgcc aagtgattga gtgtgagtta gagatataga aagaggtttg
     6001 tcatcgcaaa gaaaaaagcg acatttgtat gtcaaaattg tgggtataat tcccctaaat
     6061 atctgggacg ttgccccaac tgtgggtctt ggtcttcttt tgtggaagag gttgaggttg
     6121 ccgaggtcaa gaatgcgcgt gtgtccttga caggtgagaa aaccaagccc atgaaactag
     6181 ctgaggtgac ttccatcaat atcaatcgaa ccaagacgga gatggaggaa ttcaaccgtg
     6241 tgcttggagg cggagtggta ccaggaagtc tcgtcctcat cggtggggat cctgggattg
     6301 ggaaatcaac tcttctccta caagtctcaa cccagttgtc ccaagtgggg acagttctct
     6361 atgtcagtgg ggaggagtct gcccagcaga ttaaactacg tgcagagcgc ttaggtgata
     6421 ttgatagtga gttttatctc tatgcagaga ccaatatgca gagtgttcgt gcagaagtgg
     6481 agcgtatcca gccagacttt ctcattattg attccatcca gaccatcatg tctcctgaga
     6541 tttcaggggt gcaggggtct gtttctcagg tacgtgaagt gaccgctgaa ctcatgcagt
     6601 tggccaagac caataacatt gccatcttta tcgtaggtca tgtgaccaaa gaaggaacct
     6661 tggctgggcc tcgtatgttg gagcatatgg tggatacggt gctttacttt gaaggggagc
     6721 gtcaccacac ctttcgtatt ttgagagcgg tcaaaaatcg ttttggttcc actaatgaga
     6781 ttgggatttt tgagatgcag tcgggcggct tggttgaggt actcaatccg agtcaagttt
     6841 tcctagaaga gcgtttggat ggggcgactg gttcctccat cgttgtaacc atggaaggga
     6901 cgcgtccgat tttggcggag gttcaggctt tggtaacacc gaccatgttt ggaaatgcca
     6961 agcgtactac gacaggactt gattttaacc gtgctagctt gattatggct gttttggaaa
     7021 aacgggcagg gcttctcttg caaaatcagg atgcctatct caaatctgct ggtggtgtta
     7081 aattggatga acctgccatt gacttggctg ttgcagttgc tattgcttcg agctacaaag
     7141 acaagccaac taatcctcag gaatgttttg tcggagaact gggcttgaca ggagagattc
     7201 ggcgcgtgaa tcgtattgag caacgcatca acgaagctgc taaactgggc tttactaaga
     7261 tttatgtacc tcagaattcc ttgacaggaa tcactctgcc taaggaaatt caggtcattg
     7321 gcgtgacaac gattcaggaa gtcttgaaaa aggtctttgc ataatccgtg acaaattctc
     7381 ttaaaaatga taagatagga gaaatatttg actatcaaat tttcaaggag ggaatcgtgt
     7441 cgtattttga acagtttatg caagccaatc aggcttatgt tgccctacat gggcagttaa
     7501 atctgccact taaacccaaa acaagagtag ctattgtgac ctgtatggac tctcgtctgc
     7561 acgttgcgca agctctgggc ttggcacttg gggatgctca tatcttgcgg aatgcaggtg
     7621 gtcgagtgac tgaagacatg attcgttcgc tagttatttc ccagcaacaa atggggacaa
     7681 gagagattgt ggtattgcac catacagact gtggtgctca gacctttgaa aatgaacctt
     7741 ttcaggagta tttaaaagag gaattaggtg tagatgtgtc agaccaggac ttcttgccct
     7801 tccaagatat agaagagagt gtacgcgagg atatgcaact gcttatcgag tctcccctaa
     7861 taccagacga tgtcattatc tctggtgcca tttacaatgt tgatacagga agtatgacag
     7921 tcgtagaatt ataaatactt catttagaaa gaaagtgtat gaagaaaagc agtattttat
     7981 ttatttttat tttattgcta tgtattggtt tacagtatga aaccatctac tatacggacg
     8041 gttcgaggtc aggtgcggaa tatggactaa tgggagtttc tatctttcta gctctctttt
     8101 acatgattcc ggctctttat tttctcttcc gtattgggaa aaaatgggaa ttgccaaaga
     8161 aggttttgat tctgtcttta ttgggaggga tgttcctttc aggctggttg tctagttttg
     8221 ctaatactta tatccatgat ttactggggg ttcttttccc agatagtaca tttggtagaa
     8281 gaacccttga aattattgcc acttgttttt gttttggctt tgattcctgt gcgaaaatta
     8341 aaatctttgt ttttacttgg aattgcttcc ggtttgggat tccaaatgat tgaggatatt
     8401 ggttatattc gtacggattt gccagagggc tttgacttta ctatttcgcg aattttagag
     8461 cgtatcatct caggaattgc ctctcactgg actttttcag gtctagctgt agtaggtgtt
     8521 tacttgcttt acagagccta taaaggacag aaggttggca agaaacaggg ccttattttt
     8581 ctaggtttag ccttgggaac tcacttcttg tttaactctc cttttgtgga gttggaaaca
     8641 gagttgcctt tagcgattcc agtggttacg gctattgctc tctatggttt ttatcatgct
     8701 tattgctttg ttgagaaaca caatgagttg atgacctaga atatttttca aaagaatgat
     8761 gcaagggtac aaatatggtg cccttctttt atttttgatt gaaaaatagt gcaaaaagcg
     8821 ctacaatggt agatggaaaa tcttgtgaaa agcacaagcg atacatatat accggaggaa
     8881 atcatgtctt tttctgattt aaagctgttt gccctttctt ctaataaaga attggcagaa
     8941 cgtgtggcgc aggagattgg gatagagttg gggaaatcaa gtgttcgcca attttcagat
     9001 ggagagattc aggtcaacat tgaagaatca atccgtggga aacacgtctt tatcctacaa
     9061 tcaactagtt cgcctgtaaa tgacaatctg cttgaaattt tgattatggt agatgctttg
     9121 aagcgtgcga gtgcagaatc tgtcaatgtt gtcatgcctt actatgggta tgcacgtcag
     9181 gatagaaagg cgagagcgcg tgagccaatc acttcaaaac ttgtcgcaaa tatgcttgaa
     9241 gtagctggag tggatcgttt attgaccatc gacttgcatg ctgcgcaaat tcaaggattc
     9301 tttgatattc ctgtggatca tttgatgggt gctcctctga ttgcagatta ttttgagcgt
     9361 cgtggtatgg ttggttctga ctatgtggtt gtcagcccgg accatggagg ggtgactcgt
     9421 gctcgtaagt tggcagaatt tttgaaaaca tctatcgcta ttattgataa acgtcgtagc
     9481 gttgataaga tgaatactag tgaagttatg aacatcatcg gtaaggttga aggcaagact
     9541 tgtatcttga ttgatgatat gattgatacc gctggaacga tttgtcatgc ggcagatgct
     9601 cttgcggaag ctggtgctgt tgaagtctat gcaagctgta cgcacccagt tctttctggt
     9661 cctgctacgg acaatatcca aaaatcagct attaagaaat tggttgtttt ggataccatc
     9721 tatcttccag aagagcgttt gattgataag attgagcaga tttcaatcgc tcatctccta
     9781 ggggatgcta tcgtacgtat tcatgaaaaa cgaccacttt ctccactttt cgatattgag
     9841 aaaaaaattt aatgaccaag cctgagatga ttctcaggtt ttttcgtctt ttttccgaat
     9901 aaatagatag tagcggtgaa tctagtaaag ctagatttaa aactgtgata taataaaaag
     9961 agaagaaata tgactgtacg tcatcagaag tttcagcgac catcattttt gaacagtgat
    10021 agcacttgaa tcgacgcttt ctaaggagaa ttctagtagg tataccagtc gtttcaagat
    10081 aaggaatttt agaaggtttt tgaaagtcat atttcttcaa ttggtttccg cactcagggc
    10141 aagatggggc gtcgtagtcc agtttggcga tgatttcctt gtgtgtatcc ttattgatga
    10201 tgtttaaaat ctggacatta gggtctttaa tgtctagtaa ttttgtgata aaatgtaatt
    10261 gttccatatg attctttcta atgagttgtt ttgtcgcttt tcattatagg tcatatggga
    10321 ctttttttct acacaaaata ggctccataa tatccatagg ggatttaccc actatggata
    10381 ttatggagcc attttacaac agtgcctcaa attcagatac tgacatacct aattgctggc
    10441 tggcaacctc agaagtcaga agaccttggc gtactatgtc taggaaggca aaaagtttcc
    10501 tttcttccct tccttcaact ttcccacgct ctagtccttg ttcaaggcct tcagccctag
    10561 cagtttccaa gggatagtcc tgtgctaaca agacttgttc ttctcgcata tgtagttgac
    10621 taaacatttt cctgtcctcc tcggaccagc tcttgtagtc cagcagttgg tctgcttggc
    10681 tgatggctcg ctcaggttgc tgggtaaagg gcttgttgcc gaaaaactcc aaccatggct
    10741 tgcgaacctt gtctttgctg gtttctctgt attttttaat tccaagaatg ccatcttaac
    10801 cagatggttt tcctgtccat tgttggtaat cgccaatacc tcacctgttg tgtcttcgcg
    10861 catactaaag ctatgaaaag ccaggtcatc tgagaaataa ttactatcca cgatagcaat
    10921 ggcgtaaaca ggagcgatgt gtttgtagct ctagtgagta tcaccttctc gctgacgaat
    10981 tttttcaaga ttttgattaa cctgactgca caggtaagcc cacaagtgat tgatgaaaaa
    11041 attctgatga tggacttgaa tctcaataat tacttgagta ccgttatcca actccgccaa
    11101 gacgtctata ctggtataaa aatcctgcac cgagtaaggc atggagagta atacgtgaat
    11161 atcgcttccc tccaaaatgg tcacattttt tgctggcaag tccagcatat cgcgaataaa
    11221 ttgacaagtg atttctggat tgctgaatat tttcttagca atcaaatcat tagttgggct
    11281 gatgcccgga tgtctgagaa tcctcctatt cctccttcta tagtgagttg aaataagatg
    11341 tgaataactc tatcaggaaa gtcaaattaa tttatagaaa tattttagca gtcaaggtgt
    11401 actattatag attcaatata ctatgttata gcacattttt aaatctaggt ttactaaatt
    11461 ctctggctct atctatttat tcggaaaaag tttgaaaaat acttgctcta gctcttccca
    11521 atggtatttt ttgattcttt cctttataat gggtgtatgg ataagaaaaa attattattg
    11581 attgatgggt cttctgtagc ttttcgggcg ttttttgcgc tgtatcagca gttggaccgt
    11641 tttaagaatg cggctggttt gcataccaat gcgatttatg gtttccagtt gatgttgagt
    11701 catttgttgg agcgggttga gccgagtcat attttggtgg cttttgatgc gggaaagacg
    11761 accttccgga cagagatgta tgcggactat aagggtggtc gggccaagac tcctgatgag
    11821 tttcgtgagc aatttccttt cattcgtgag ttgctggatc atatggggat tcgtcactat
    11881 gagctggctc agtatgaggc ggatgacatc attgggacgc tggataagct agcagagcag
    11941 gatggttttg atattaccat tgtcagtggg gacaaggatt tgattcagct gacggatgag
    12001 catacggtgg ttgaaatttc caagaaaggt gtggctgagt ttgaggcctt tacgccagat
    12061 tacctcatgg aagaaatggg cctcacacca gctcagttta tcgatctcaa ggcgctcatg
    12121 ggtgataagt cggataatat ccctggggtg accaaagtcg gtgaaaagac gggtattaag
    12181 ctcttgctgg agcatggttc gcttgagggg atttatgaaa atattgatgg aatgaagact
    12241 tctaagatga aggaaaatct catcaatgac aaggaacagg cctttttgtc taaaacacta
    12301 gcgaccattg ataccaaggc accgattgcg attggtttag aggacttggt ctatagtggt
    12361 ccagatgttg aaaatcttgg gaaattctac gatgagatgg gcttcaaaca gctcaagcag
    12421 gctttaaatg tgtcgtcagc tgatgtggct gagggtttgg attttactat tgttgaccaa
    12481 atcagtcaag atatgctgag tgaagagtct atcttccact ttgagctttt tggtgagaat
    12541 taccatacgg ataatttggt tggatttgcc tggtcttgtg gggataagct ctatgccaca
    12601 gacaagcttg agctgttgca agacccgatt ttcaaggatt tcttagaaaa aacatctctg
    12661 agagtttatg actttaagaa ggttaaagtt cttttgcaac gttttggtgt ggatttgcag
    12721 gcgcctgctt ttgacatccg tttggctaaa tacctccttt cgactgtgga ggacaatgaa
    12781 attgcgacca tcgctagtct ttatggtcag acttacttgg ttgatgatga aactttctac
    12841 ggtaagggtg ttaaaaaggc cattcctgaa cgtgagaaat tcttggaaca cttagcttgt
    12901 aaacttgctg ttttggtaga aacagagcct attttacttg aaaaactcag cgaaaatggg
    12961 caattagagc ttctttatga tatggagcaa cctctggctt ttgttcttgc caagatggaa
    13021 attgctggga ttgtggtcaa gaaagagacc ttgcttgaga tgcaggctga aaatgagctt
    13081 gtcattgaaa aactgactca agagatttac gagctggctg gtgaggagtt taatgtcaac
    13141 tcgcctaagc agttgggcgt gcttctcttt gagaaattgg gacttcctct agaatacact
    13201 aagaaaacca agacaggtta ttcgacagca gtggatgtgt tggagcgtct cgctcctatt
    13261 gctccgattg ttaagaaaat cctggattac cgtcaaattg ctaagattca atctacttat
    13321 gtaattggct tgcaggactg gattttggct gatggaaaga ttcatactcg ctatatgcag
    13381 gatttgaccc agaccgggcg tttgtctagt gtggatccaa acttgcaaaa tattcctgcc
    13441 cgattggaac aagggcgctt gattcggaag gcttttgtgc cagagtggga ggatagtgtg
    13501 ctactcagct ctgactattc acagattgaa ttgcgcgttt tggcgcatat ttctaaggat
    13561 gagcacttga ttaaggcctt ccaagagggg gcagatatcc atacttcgac agccatgcgg
    13621 gtctttggca ttgagcgtcc tgataatgtg actgcaaatg accgtcgcaa tgccaaggca
    13681 gttaactttg gagtggttta tgggatttca gactttggct tgtctaataa tttgggaatt
    13741 agtcgtaagg aagccaaagc ctacattgat acctactttg aacgttttcc aggtattaaa
    13801 aactacatgg atgaagtggt gcgggaggcg cgtgataaga gctatgtaga gaccctcttt
    13861 aagcgtcgcc gtgagttgcc agatatcaat tcgcgcaact tcaatattcg tggttttgcg
    13921 gagcgaactg ctatcaactc acctatccag ggttcggcag cagatattct caagattgcc
    13981 atgattcagc tggataaagc cttggttgca ggtggttatc agaccaagat gctgttacaa
    14041 gtgcacgatg aaatcgtcct tgaagtgcct aaatctgaat tggtagagat gaaaaaattg
    14101 gtgaaacaaa ccatggaaga agccattcaa ctcagtgttc ctcttatcgc agatgagaat
    14161 gaaggggcaa cctggtacga ggctaaataa aaagggggct agtcctcctt ttttgtagta
    14221 gaattctgca aaccttttca aaatgtgcta tactgatgaa aaaggaggat ttctatgagt
    14281 caagaattta tcaatccaag tgatggcgtg attcgtcagt atctcgcaac gagtaaaacc
    14341 cttgctgtgg tgggtttgtc tgaccgtgaa gaaacaacca gtaatcgagt aacaaaggaa
    14401 atgcaggctc ggggctataa aatcatccca gtcaatccca agacggcagg tggcgaaatc
    14461 ttgggtgaaa aggcttatgc tagcctcgct gaaattcctt ttcctgtaga tattgtcaat
    14521 gtttatcgtc gcagtgaatt tctgcccgat gtggcgcgtg attttctcaa agctgatgcc
    14581 aagatttttt gggcacagct aggacttgaa agtttagaag cgaaagagat tttgcgtgat
    14641 ggtggatgtg atgatatcgt gatgaatcgc tgtatcaaga gagaacatac tcgcttgatt
    14701 gaggaagcat aagaaaaagg tagctgatgg gctacctttt gtgttatact caatgaaaat
    14761 caaagagcaa actaggaaac tagctgcggg ttgctcaaaa cactgttttg aggttgcaga
    14821 tagaactgac gaagtcagct caaaacaccg ttttgaggtt gtagatagaa ctgacgaagt
    14881 cagctcaaaa caccgttttg aggttgtaga tagaactgac gaagtcagta acatatatac
    14941 ggcaaggcga cgttgacgtg gtttgaagag attttcgaag agtattagaa aatgccgata
    15001 agggtctgca taccaaggct ggtgaggatg atggcaatcc agcagacggc tccgagaaca
    15061 atggattttc cactagattt gaccatagcg accagattag ttttgagacc gatggcactc
    15121 atggccatga taatgaggaa tttagagagt tgtttgagag gggtaaagaa actactagac
    15181 acaccgagag aggtcagaag ggtggttagg agcgatgcaa ggatgaagta aaggataaaa
    15241 agtgggaaga cttttttcag ttgtaagcct tgcttatttt tttgctcgcg actttgccag
    15301 taggagagaa agagagtgat ggggatgata gctagggtgc gcgtgagttt gacaatggtt
    15361 gcagattcga gggtattggt ctggtagaga ctgtcccaag cgctagctgt ggcggttaca
    15421 gaggaagtat cattgaccgc agttcctgca aagagggcga agccgtcatt ggatagatga
    15481 agccaggtac cgagggttgg aaagatgagc gcagccaaga cattgaagaa aaagataacg
    15541 gagatggctt gggctacttc cttttcctta gcatggataa caggcgctgt cgctgcaatg
    15601 gcagaacccc cacagataga agaacctact ccaatcaagg tagccagttt tgtatccagg
    15661 gcaaagaagc gctggaagag gtaggcaaca atcaaggcta ttgaaatggt ggaaaggatg
    15721 acagggagtg aagattgccc aactgcgaag acttgagaga tattgagacc aaaaccaagt
    15781 aagataacgg catactggag caatttcttg gaactaaagg tcaatccagc atccagttgt
    15841 ttatgagacg agagaaaggg atgtaggagc atgcccataa aaatcgcaaa aacgggtgcg
    15901 ccaatcacag ggaagaatcc tcctaagtac caagatagga tggaaatgag aaggcagacc
    15961 aagatgcctg ctccattttt tgatagaaat gacataaaaa cctccaaata gaatctgtta
    16021 ccattataga cctgtaaaca ggaaaagtaa aatagaaagt ggaaagctat tctctaatgt
    16081 atttttgcgg tcggggggct tttgtagtat aatagagata cgttttgaaa gtaggaggta
    16141 tctatggact taactaagcg ctttaataaa cagttagata aaattcaagt ttcgttgatt
    16201 cgtcagtttg accaggctat ttcggagatt cctggggtct tgcgtttgac cttgggggaa
    16261 cctgatttta caacgccaga ccatgtcaag gaggcggcca agcgagcgat tgatcagaac
    16321 caatcctact atacagggat gagtggtctg ctgactctac gtcaggcagc cagtgacttt
    16381 gttaaggaaa agtaccaact ggactatgct cctgaaaatg aaatcttggt tacaattggg
    16441 gcgacagagg ctttatctgc gactttgacg gctattttgg aagagggcga caaggtactt
    16501 ttgccagctc ctgcttatcc aggctatgaa ccgattgtta acttagttgg ggcagaaatt
    16561 gttgagattg atacgactga aaatggtttt gtcttgactc ctgagatgtt ggagaaggcc
    16621 attttggagc agggtgataa gctcaaggcg gttattctca actatccagc caatccgaca
    16681 ggaattacct acagtcgaga gcagttagag gccttggcag ctgttttacg caagtacgaa
    16741 atttttgttg tctgtgatga ggtttactca gaattgacct acacaggcga agcccatgtg
    16801 tctctaggaa cgatgttgag agaccaggct attattatca atggtttgtc taaatcgcat
    16861 gccatgacag gttggcgttt ggggctgatt ttcgctcctg cggccttcac agcccagtta
    16921 atcaagagtc accaatactt ggtcactgcc gcaaatacca tggcgcaaca tgctgcggta
    16981 gaagccttga cggctggtaa aaatgatgcg gagcccatga agaaggaata tatccagcgt
    17041 cgggactata tcatcgaaaa aatgactgct cttggttttg agattatcaa accagacggt
    17101 gccttctata tttttgctaa aattccagcg ggctacaatc aagactcctt tgcttttctg
    17161 aaggattttg ctcagaagaa ggccgttgcc tttatccctg gtgcagcctt tggacgttac
    17221 ggggaaggct acgtccgcct atcttatgca gccagcatgg agactatcaa agaagccatg
    17281 aaacgacttg aggagtacat gagagaagca tgattcagtc tatcacgagt caaggcttgg
    17341 tgctttacaa tcgcaatttt cgtgaggatg acaagctcgt caaaattttt acagagcagg
    17401 ttggcaaacg catgtttttt gtcaaacacg ctggtcagtc taagctggcg cctgttattc
    17461 agcccttggt gctggcacga tttctattgc gaatcaatga tgacggactc agttacatcg
    17521 aagactatca tgaggtcatg acttttccca agattaatag tgacctcttt gtcatggcct
    17581 atgcgaccta tgtggcagct cttgcagatg ctagtttgca ggacaatcag caggatgctc
    17641 ccttgtttgc ttttttgcaa aagactttgg agttgatgga agcaggcttg gattatcagg
    17701 ttttgaccaa tatttttgaa attcaaattt tgactcgatt tggaatcagc ctcaatttta
    17761 atgagtgtgt cttctgccat cgggttggtc aggcttttga cttttctttc aaatatggag
    17821 cctgcctctg tccagagcat tatcatgagg ataagagacg ttgtcatctc aatcccaata
    17881 tcccctatct gctcaatcaa tttcaagcta ttgattttga gactttggag accatttcgc
    17941 tcaagcctgg aatcaagcaa gagctacgcc aatttatgga tcaactatat gaagagtacg
    18001 ttgggattca cctaaaatca aagaaattta ttgattccct agcagactgg ggacaattac
    18061 taaaagagga aaagaaatga aaaaaatcgc agtagatgcc atggggggcg attacgcacc
    18121 tcaggccatt gttgagggtg tcaatcaagc cctatctgac ttttcagata tcgaggttca
    18181 actttacgga gatgaagcta aaatcaagca atatctgaca gcgacagagc gcgtcagcat
    18241 tatccatacg gatgagaaga ttgattcgga tgatgaacct acgagagcta ttaggaataa
    18301 gaaaaatgcc agtatggtat tggcagccaa ggctgtcaaa gatggtgaag cagacgctgt
    18361 cctttcggct gggaatacag gtgccttgtt ggctgctgga ttcttcatcg tgggtcgtat
    18421 caagaatatc gaccgtcctg ggcttatgtc gactttgccg actgtagatg ggaagggatt
    18481 tgacatgcta gacctcggtg ccaatgcgga aaatacagcc cagcacctcc atcaatacgc
    18541 ggttctagga tccttctatg ctaaaaatgt tcgtggcatt gcgcaaccac gtgttggctt
    18601 gctcaataac ggaacagaga gtagcaaggg cgatccgctt cgtaaggaaa cttatgaatt
    18661 actagtggct gatgaaagtt tgaactttat cggaaatgtg gaagcgcgtg atttgatgaa
    18721 tggtgttgca gatgttgttg tggcagatgg tttcacggga aacgctgtgc tcaaatccat
    18781 cgaagggaca gctatgggaa tcatgggctt gctcaagaca gctattacag gtggtggtct
    18841 tcgagcgaaa ctaggtgccc tccttctcaa ggacagcctc agaggtttga aaaaacagct
    18901 caattattca gatgttggtg gagcggtctt gtttggtgtt aaggcacctg ttgtcaagac
    18961 tcatggctca agcgatgcca aggctgttta tagtacgatt cgccagattc gtaccatgct
    19021 agaaacagac gtagttgccc agactgcgcg tgaattttca ggagaataaa agagatgaca
    19081 gaaaaagaaa tttttgaccg tattgtgacc attatccaag agcgacaggg agaggacttt
    19141 gtcgtgacag aatccttgag tctgaaagac gatttggatg cggattctgt tgacttgatg
    19201 gagtttatct tgactctgga agatgaattt agtatcgaaa tcagcgatga agaaattgac
    19261 caactccaaa acgtaggaga tgtggttaaa atcattcaag gaaaatagca atcggagttc
    19321 caagtcaacg gaagtagatg gtttttagaa atgagaaata tcggacaagc tggtaaaatc
    19381 ttggctgaca gtggttatca agggctcatg aagatatatc ctcaagcaca aactccgagg
    19441 aaatcaagta aacttaagcc attaactctt gaagataaag cctgtaatca tgcgctatct
    19501 aaggagagaa gcaaggttga gaatatctt
//
LOCUS       DAVLGK010000041        18826 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLGK010000041 DAVLGK010000000
VERSION     DAVLGK010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18826
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.041"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..2390
                     /locus_tag="VXE01_001667"
     CDS             <1..2390
                     /locus_tag="VXE01_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="zinc metalloprotease"
                     /protein_id="HEV0750532.1"
                     /translation="LNKEHHLNTKEVLSVTAMNNNEFITNLDEANKIIVHYADGTKDY
                     FNLSSSSEGLSNVKEYTITDLGIKYTPNIVQKDNTTLVNDIKSILESVELQSQTMYQH
                     LNRLGDYRVNAIKDLYLEESFTDVKKNLTNLITKLVQNEEHQLNDSPAARQMIRDKVE
                     KNKAALLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGEKVSVLDRLIEIGSKENNIK
                     GSRTFDAFGQVLAKYTKSGNLDAFLNYNRQLFTNIDNMNDWFIDATEDHVYIAERASE
                     VEEIKNSKHRAFDNLKRSHLRNTILPLLNIDKAHLYLISNYNAIAFGSAERLGKKSLE
                     DIKDIVNKAADGYRNYYDFWYRLASDNVKQRLLRDAVIPIWEGYNAPGGWVEKYGRYN
                     TDKVYTPLREFFGPMDKYYNYNGTGAYAAIYPNSDDIRTDVKYVHLEMVGEYGISVYT
                     HETTHVNDRAIYLGGFGHREGTDAEAYAQGMLQTPVTGSGFDEFGSLGINMVFKRKND
                     GNQWYITDPKTLKTREDINRYMKGYNDTLTLLDEIEAESVISQQNKDLNSAWFKKIDR
                     EYRDNNKLNQWDKIRNLSQEEKNELNIQSVNDLVDQQLMTNRNPGNGIYKPEAISYND
                     QSPYVGVRMMTGIYGGNTSKGAPGAVSFKHNAFRLWGYYGYENGFLGYASNKYKQQSK
                     TDGESVLSDEYIIKKISNNTFNTIEEFKKAYFKEVKDKATKGLTTFEVNGSSVSSYDD
                     LLTLFKEAVKKDAETLKQEANGNKTVSMNNTVKLKEAVYKKLLQQTDSFKTSIFK"
     gene            2451..4172
                     /gene="pabB"
                     /locus_tag="VXE01_001668"
     CDS             2451..4172
                     /gene="pabB"
                     /locus_tag="VXE01_001668"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV0750533.1"
                     /translation="MHRKTVIDFRTLGERYTFTKPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSSIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELQVIGL"
     gene            4292..5818
                     /locus_tag="VXE01_001669"
     CDS             4292..5818
                     /locus_tag="VXE01_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0750534.1"
                     /translation="MKSKIVLGASLAIATLSLVSLVEIEGLSPFLIENVSANTHSANK
                     VINHKVSIYLENADEGKGLTVNFSTDSVSPNLFDEFEKKSGITITTMLVNAKTGEVVE
                     KRLTPSVFLRSNDLTSGTISSFIFSEYPDGEYKYVVSKGDFIDPKTQFKHQYRGESPV
                     FRIRNRKYVELGTTDKKLDERRDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSV
                     NSNLLNSFGEKAKKVLIRSKLINVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDL
                     TDGEYKYVAYESQQYTDPQTTLTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPK
                     PDEKPKPSAPQQEKPKPTVQSGWVGSSYYQNGKKVTSKWIFDKKYNSYFYLDASGNYV
                     QNAWVGNYYLKSGGYMAKSEWIYDKNYGSYYYLTSEGSYARNTWSGNYYLKSNGKMAK
                     SEWVYDSNYKSYYYLTSEGSYARNTWVGNYYLKSNGKMAVNERTPDGYRVDGSGKWVK
                     "
     gene            5905..6824
                     /locus_tag="VXE01_001670"
                     /pseudo
     CDS             5905..6824
                     /locus_tag="VXE01_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            6959..7918
                     /locus_tag="VXE01_001671"
     CDS             6959..7918
                     /locus_tag="VXE01_001671"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV0750535.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            8015..8854
                     /locus_tag="VXE01_001672"
     CDS             8015..8854
                     /locus_tag="VXE01_001672"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV0750536.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(8902..9072)
                     /locus_tag="VXE01_001673"
     CDS             complement(8902..9072)
                     /locus_tag="VXE01_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV0750537.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            9193..10077
                     /gene="miaA"
                     /locus_tag="VXE01_001674"
     CDS             9193..10077
                     /gene="miaA"
                     /locus_tag="VXE01_001674"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV0750538.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            10070..11308
                     /gene="hflX"
                     /locus_tag="VXE01_001675"
     CDS             10070..11308
                     /gene="hflX"
                     /locus_tag="VXE01_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV0750539.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQFKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            11301..11924
                     /locus_tag="VXE01_001676"
     CDS             11301..11924
                     /locus_tag="VXE01_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV0750540.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            11939..12868
                     /locus_tag="VXE01_001677"
     CDS             11939..12868
                     /locus_tag="VXE01_001677"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV0750541.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            12889..13644
                     /locus_tag="VXE01_001678"
     CDS             12889..13644
                     /locus_tag="VXE01_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0750542.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(13698..14606)
                     /locus_tag="VXE01_001679"
     CDS             complement(13698..14606)
                     /locus_tag="VXE01_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0750543.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            14670..14939
                     /locus_tag="VXE01_001680"
     CDS             14670..14939
                     /locus_tag="VXE01_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV0750544.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            14939..15319
                     /locus_tag="VXE01_001681"
     CDS             14939..15319
                     /locus_tag="VXE01_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0750545.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            15408..15578
                     /locus_tag="VXE01_001682"
     CDS             15408..15578
                     /locus_tag="VXE01_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750546.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNI"
     gene            complement(15675..16400)
                     /locus_tag="VXE01_001683"
     CDS             complement(15675..16400)
                     /locus_tag="VXE01_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0750547.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            16562..18403
                     /gene="typA"
                     /locus_tag="VXE01_001684"
     CDS             16562..18403
                     /gene="typA"
                     /locus_tag="VXE01_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV0750548.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            18423..18677
                     /locus_tag="VXE01_001685"
     CDS             18423..18677
                     /locus_tag="VXE01_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV0750549.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
BASE COUNT         5865 a         3400 c         4101 g         5460 t
ORIGIN      
        1 aattaaataa agaacaccat ctaaatacta aagaagttct ttctgttacc gcgatgaaca
       61 acaatgagtt tatcacaaac ctagatgaag ctaataaaat tattgttcac tatgcggacg
      121 gtacaaaaga ttactttaac ttgtcttcta gcagtgaagg tttaagtaat gtaaaagaat
      181 atactataac tgacttagga attaaatata cacctaatat cgttcaaaaa gataacacta
      241 ctcttgttaa tgatataaaa tctattttag aatcagtaga gcttcagtct caaacgatgt
      301 atcagcatct aaatcgatta ggtgactata gagttaatgc aatcaaagat ttatatttag
      361 aagaaagctt cacagatgtt aaaaaaaact taacaaacct aatcacaaaa ttagttcaaa
      421 acgaagaaca tcaactaaat gattctccag ctgctcgtca aatgattcgt gataaagtcg
      481 agaaaaacaa agcagcttta ttactaggtt taacttacct aaatcgttac tatggagtta
      541 aatttggtga tgttaatatt aaagaattaa tgctattcaa accagatttc tatggtgaaa
      601 aagttagcgt attagacaga ttaattgaaa tcggttctaa agagaacaac attaaaggtt
      661 cacgtacatt cgacgcattc ggtcaagtat tggctaaata tactaaatca ggtaatttag
      721 atgcattttt aaattataat agacaattgt tcacaaatat agacaatatg aacgattggt
      781 ttattgatgc tacagaagac catgtctaca tcgcagaacg cgcttctgag gtcgaagaaa
      841 ttaaaaattc taaacatcgt gcattcgata atttaaaacg aagtcacctt agaaatacta
      901 tactcccact actgaatatt gataaagcac atctttattt aatttcaaat tataatgcaa
      961 ttgcctttgg tagtgcagag cgattaggta aaaaatcatt agaagatatt aaagatatcg
     1021 ttaacaaagc tgcagatggt tatagaaact attatgattt ctggtatcgt ctagcgtctg
     1081 ataacgttaa acaacgacta ctaagagatg ctgttattcc tatttgggaa ggttataacg
     1141 ctcctggtgg atgggttgaa aaatatggcc gctataatac cgacaaagta tatactcctc
     1201 ttagagaatt ctttggtcct atggataagt attataatta taatggaaca ggagcttatg
     1261 ctgctatata tcctaactct gatgatatta gaactgatgt aaaatatgtt catttagaaa
     1321 tggttggtga atacggtatt tcagtttaca cacatgaaac aacacacgtc aacgaccgtg
     1381 cgatttactt aggtggcttt ggacaccgtg aaggtactga tgctgaagca tatgctcagg
     1441 gtatgctaca aactcctgtt actggtagtg gatttgatga gtttggttct ttaggtatta
     1501 atatggtatt taaacgcaaa aatgatggga atcagtggta tattacagat ccaaaaactc
     1561 taaaaacacg agaagatatt aatagatata tgaagggtta taatgacact ttaactcttc
     1621 ttgatgaaat tgaggctgaa tctgtgattt ctcaacaaaa taaagattta aatagtgcat
     1681 ggttcaaaaa aatagataga gaataccgtg ataacaataa attaaatcaa tgggataaaa
     1741 ttcgaaatct aagtcaagaa gagaaaaatg aattaaatat tcaatctgtt aatgatttag
     1801 ttgatcaaca attaatgact aatcgcaatc caggtaatgg tatctataaa cccgaagcaa
     1861 ttagctataa cgatcaatca ccttatgtag gtgttagaat gatgaccggt atctacggag
     1921 gtaatactag taaaggtgct cctggagctg tttcattcaa acataatgct tttagattat
     1981 ggggttacta cggatacgaa aatgggttct taggttatgc ttcaaataaa tataaacaac
     2041 aatctaaaac agatggtgag tctgttctaa gtgatgaata tattatcaag aaaatatcta
     2101 acaatacatt taatactatt gaagaattta aaaaagctta cttcaaagaa gttaaagata
     2161 aagcaacgaa aggattaaca acattcgaag taaatggttc ttccgtttca tcatacgatg
     2221 atttactgac attgtttaaa gaagctgtta aaaaagatgc cgaaactctt aaacaagaag
     2281 caaacggtaa taaaacagta tctatgaata atacagttaa attaaaagaa gctgtttata
     2341 agaaacttct tcaacaaaca gatagcttta aaacttcaat ctttaaataa ttgaaatctc
     2401 tcgtctgctt tgcggatgag ggttttctta ttttatgcta tacttaaggt atgcatagaa
     2461 aaacagtgat tgattttagg actttggggg agagatatac ctttaccaag cctattaaag
     2521 agttgaaaac gagaaatgta gaagaagtgg cagatttgct ggcacaagtg gaaagctacc
     2581 aagagcaagg ttattatgtg gtggggtatg tcagctacga ggctgcacct gcttttgagg
     2641 aaaaattagc agttcacaag gatcccctac tgggagagta cctgctttat tttactgttc
     2701 atgatagcgt agaaacttcc tctattcctc tgacttatga ggatattgat ttgccctcaa
     2761 attggcagga agtaacgtct gcagcagact atgaaaaggc cattgcccaa attcaccatc
     2821 atttacggca gggagatacc tatcaggtca actacaccgt ccaacttaag caaaagttaa
     2881 atgccaatcc ttttgccatc tacaatcgta tggtggtaga gcaggaggcg ggctacaatg
     2941 cctatgtgga acatgacgag atggcagtga tttccatgag cccagagctc ttttttgagc
     3001 aaaatgatcg cgagttgaca acacgaccaa tgaaggggac gactcagcgt ggggtaactg
     3061 accaagaaga tcttgaacag gccagttggt tggaacagga tcccaaaaat cgctctgaaa
     3121 atatgatgat tgtggacctc ttgcgcaatg atatgaaccg tatttctgaa gttgggagcg
     3181 agcacgtgga gcgtctgtgt caggtagagc agtattcaac tgtttggcag atgacttcga
     3241 ccatcaagag tcagttgcga gaggatgtgg accttgttga aatcttccgc tcactctttc
     3301 cttgtggttc cataacgggt gcaccgaaaa ttgcgacaat ggagattatc aaggacttgg
     3361 agcctcaacc gcgtggagtc tactgtggaa cgattggtct cttgcttcca aatggacgac
     3421 ggatttttaa tgtggccatt cgtaccattc aacttcacaa aggtcaagcc atttatggag
     3481 ttggcggagg gattacttgg gatagcacat gggaatctga ataccgagag gttcatcaaa
     3541 aggcagcagt tctttatcgt aaacaagctc gcttccaact gattacgaca ggggaaatca
     3601 gccagaagaa cctgttgttt gaagatcaac atctggaaag actgagaaaa gctagtcgtt
     3661 attttgcctt tccttttgat gcagaagact tgggacacaa gattgaggaa gagtgtcagg
     3721 attgtgaagc taatcgagat taccgcttgc gaatcagcct tagcaaatct ggagagatag
     3781 aagtcaatcg tcaagtatta acccctctca gtacaagctt ttgtcaggcc caagtctgcc
     3841 ttcaggaagc tgctttgaat caatccttta cctactttaa aaccactcac cgaccgcatt
     3901 tgagcctagg agaacaagag aagatttacc acaataagtc aggagaactg cttgaaacct
     3961 ctataggaaa tttggttctg aaaatcgctg gaaaactcta cacaccgcct atccgacttg
     4021 gaatcttgcc aggaatttac cgtcagtatt tgctagaaac aggacaggta gaagagaaag
     4081 tcttgacctt ggcagattta gcccaagcag aagctattta cggctgtaat gcagtgagag
     4141 gcttgtatga gttgcaagtg ataggattgt gagttttagc tattaatagt ttttaatata
     4201 tattaaaata tattggtgtt tacttttgat gagatatcat atttgtgtta taatgtaacc
     4261 gtaaacaata gaaatttaaa ggagattttt gatgaaatca aaaatagttt tgggagcttc
     4321 gctagcgatc gcaacactta gcttagtatc tcttgtcgag attgaaggac tctcaccgtt
     4381 tttaatagag aatgttagcg caaatactca ttctgcaaat aaagttatta atcataaagt
     4441 aagtatttac ttagaaaatg ctgatgaagg taaaggtcta actgtaaact tttcaacaga
     4501 cagtgttagt ccaaatttat ttgatgagtt cgaaaaaaag agtggaatta caataactac
     4561 tatgttagtg aatgctaaga caggtgaagt tgtagaaaaa agattaacac caagcgtttt
     4621 tttacgttcc aatgatttaa ccagtgggac catatcttcg tttattttta gtgaatatcc
     4681 tgatggagaa tataaatatg ttgtgtctaa aggagacttt atcgatccta agactcagtt
     4741 taaacatcag tatagaggag aatctccagt ttttagaata cgtaatcgaa aatatgtgga
     4801 gttgggaaca actgataaaa aattagatga aagacgtgat aatagcgttt ataaagatgg
     4861 ggttgttgaa cacaaggtaa atttaagttt aacaagttat caaggaggta atggagttac
     4921 tgcaattttt tcaactgata gtgttaactc taacttactt aattcttttg gtgaaaaggc
     4981 taaaaaagtt ttgattaggt ctaagttaat taatgttaag actggcgagg ttattgatga
     5041 aacgttttct ccaaaagtaa gtttaacctc taaaattttg aaaagtggtt ctacagcagt
     5101 attttatttt atagatttaa ctgatggcga atataaatat gttgcgtatg aaagccagca
     5161 atatactgat cctcaaacaa cattgactca tcagtataga ggagaatctc ctatttttag
     5221 tatcaaagat ggaaaatttt ctggtttagt atctgcctca aaaccagacg aaaacccgaa
     5281 gccaacgcca aaaccggatg agaaaccaaa accttcagca ccacaacagg agaaaccaaa
     5341 acctacagtt cagtctggtt gggtaggttc atcttattat caaaatggta aaaaagtcac
     5401 tagtaagtgg atttttgata aaaaatataa ttcatacttc tatctagatg catcaggaaa
     5461 ttatgttcaa aacgcttggg taggtaacta ttatctcaaa tcaggcggat acatggctaa
     5521 aagtgagtgg atttatgata agaactatgg ttcatactac tatctaacat cagaaggcag
     5581 ctacgctcgt aacacttggt caggcaatta ttatttgaag tcaaatggta agatggctaa
     5641 aagtgagtgg gtatacgata gtaactacaa atcatattac tacttgacat cagaaggaag
     5701 ttatgctcgt aacacttggg taggcaatta ctatcttaaa tcaaacggta aaatggctgt
     5761 taatgaacgt acaccagatg gttatcgtgt agatggttca ggtaaatggg ttaaataaga
     5821 aactaaaaaa taggataata ggtaatatca gatgaataaa aaaaattatt ttcatgtgct
     5881 ttagcatttt caacgattgg aacattgtca acgattgata aatcaggagt tcttcctttt
     5941 tcagcgcaaa cggtgcaggc tgacatacaa acgcttaccc caatggcaaa atattatatt
     6001 attcttccga aggatgcaga aatatataaa acttggagag gtactgtcaa tattcccatt
     6061 attgatgcta caaaaactac tccagaatta tcttatttca aagaagatca tcgcaactat
     6121 atagctaatg agaataagtc tggtgccaat tacatagagt ggaagggaac agtagaagag
     6181 tttaaagagg ccattaagaa gttgactgat aaaaaatcaa ctactgcaac accaaaaaag
     6241 gatgaaaagc caacaccaaa accggatgag aagccaaaac caacacctac agttcagtct
     6301 ggttgggtag gttcatccta ttatcaagat ggtaaaaaag tcattagtaa gtggattttt
     6361 gataaaaaat ataattcata cttctatcta gatgcatcag gaaattatgt tcaaaacgct
     6421 tgggtaggta actattatct taaatcaggc ggatacatgg ctaaaggtga atgggtttat
     6481 gatgccacct atcaagcttg gtattatttg acatcagatg gttcttatgc ttacagtaca
     6541 tggcaaggaa attactatct aaaatcggat ggtaaaatgg ctgtcaatga atgggttgat
     6601 ggtggacgtt attatgttgg cgctgacgga gtttggaagg aaggtcaagc aagtacagct
     6661 tcttctagta atgatagcaa tagtgaatat tctgctgctt taggaaaggc aaaaagttat
     6721 aattcgttat tccacatgtc aaaaaaaaac gtatgtatag acaattaact tctgattttg
     6781 ataaattttc aaatgatgca gctcaatatg ccattgatca ttagatgatt aacagatact
     6841 ggtaggcgaa aaaattcctt ataattcatt tacgcaaacc tttgcataag tgaatggatt
     6901 ttgatatact agtactgtaa gcattttcaa ttactacaca atgaaaaagg agaatatgat
     6961 gagtcaaaag attattggga ttgaccttgg tggaacttct atcaaatttg caatcttaac
     7021 aacagcagga gaaatccaag gaaaatggtc aatcaagacc aacattttgg atgagggaag
     7081 tcatatcgtt gatgatatga ttgagtctat tcaacatcgt ttggacttgc ttggattggc
     7141 agcagcggac ttccaaggca ttggaatggg atcaccaggt gtggttgacc gtgacaaagg
     7201 gactgttatc ggtgcctaca acttgaactg gaaaaccctt caaccaatca aacaaaagat
     7261 tgaaaaagct ttgggcattc catttttcat cgataatgat gccaacgtag cagctcttgg
     7321 tgagcgctgg atgggtgctg gagataacca accagacgtt gtctttatga cactcggtac
     7381 tggtgttggt ggcggtatcg tcgcagaagg caaattgctt cacggtgttg ctggtgcagc
     7441 aggtgagctt ggtcacatca ctgttgactt tgaccagcca atctcatgta cttgcggtaa
     7501 gaaaggctgc cttgagacag ttgcttcagc aacagggatt gtcaacttga ctcgtcgcta
     7561 tgccgatgaa tacgaaggcg atgcagcctt gaaacgcttg attgataatg gagaagaagt
     7621 aactgctaag actgtctttg atctcgcaaa agaaggagac gaccttgctt tgattgttta
     7681 ccgtaacttc tcacgttact tgggaatcgc ttgtgctaac attggttcaa tcctaaaccc
     7741 atcaacaatc gtcatcggtg gtggtgtgtc agctgcggga gaattccttc tacaaggtgt
     7801 tcaaaaagtt tacgatgaaa atagtttccc acaagtacgc acatctacta aattagctct
     7861 tgcaactcta ggaaatgacg ctggagttat cggagcagca tcacttgtat tgcaataaga
     7921 taatgagaga ggaaaatgct aacctagagt tagtaatgtt cctcttttat tttttatgct
     7981 atactagtta ggacaatgaa tgaggtgaga gtaaatgaca aaagcagata cgatttttaa
     8041 agagaatatt gaacgcattc taaaggaagg tgttttctca gagcaggctc gtcctaagta
     8101 caaggatggg actgttgcta attccaagta tgtaactggt gccttttccg agtacgactt
     8161 atctaaagga gaatttccta tcacaacctt gcgtcccatt gcaatcaaat ccgccatcaa
     8221 agaagttctc tggatttacc aagaccagtc aaatagctta gaagtgctta atgacaagta
     8281 caatgttcac tactggaatg actgggaagt tggagacacg ggaaccattg gtgagcgcta
     8341 tggtgccgtt gttaagaaac acgacattat caataagctt ctcaaacagt tggaaaccaa
     8401 tccttggaac cgccgcaata ttatttcgct ctgggattac caagctttcg aagaaacaga
     8461 tgggctgctc ccgtgcgcct ttcagaccat gtttgatgtt cggcgtgttg atggggaaat
     8521 ctatctggat gcgaccttga cccagcgctc caatgatatg ctggtggccc accacatcaa
     8581 cgctatgcag tatgtggctt tgcagatgat gattgctaaa cattttggct ggaaggttgg
     8641 gaagttcttc tacttcatca acaacctcca tatctatgat aatcaatttg aacaagctca
     8701 ggaattgctc cgtcgggagc cgtcaaactg ccaaccacgc ttggttttaa atgttcctga
     8761 tgggactaat ttctttgata tcaaagcaga agattttgag ttggtggatt atgaccctgt
     8821 taagccacag ttgaagtttg acctagctat ttaaaagaat agaaaaaaga agttgagaat
     8881 aatcccaact tcttttgttt cttaacgtga tacgcggcga cgagctgctt ttttacggtt
     8941 ttcttcgatg aaagctgctt tttgctcttc tggttcgatt actttctttt taaatgcgta
     9001 tactgcacct gcaacggcag cgacagttcc tgcgacacct gttacaagac ctttagcgaa
     9061 tcctttagcc atgagtcttc ctcctttata ttctcaatca gccagcctcc tcaagaggtc
     9121 acatttttct gactgacctt tttgtgttat aataatagta acgaaaaaat gggaattttt
     9181 caaggaaaaa agatgaaaac aaaaataatt gtgattgttg gaccgactgc tgttggaaag
     9241 acggctctag ctattgaggt tgcaaagcgc tttaatggcg aagtggttag tggagatagc
     9301 cagcaagtct atcgaggact tgatattggg acggccaagg ctagtccaga agagcaggca
     9361 gctgttcctc atcatttaat cgatgttaga gagataaccg agtcttactc ggcttttgat
     9421 tttgtttcag aagctaagat gactattgag gatattcaga gccgtggcaa gctagccatt
     9481 atcgccggtg ggactggact ttatatccag agcttgctag aaggttacca cctaggtggg
     9541 gagactcctc atgaggagat tttagcttat cgagctagtt tggagccata ttcagatgag
     9601 gaattagccc atttggtgga gcaagcaggc cttgagattc cccagtttaa tcgtcgtcgt
     9661 gctatgcgtg ccttagaaat tgcccatttt ggtcaggatt tggaaaatca agagatcttg
     9721 tatgaaccgc tgattatctg cttggatgat gaacgtagtc aactttatga gcgtatcaac
     9781 caccgagtgg atttgatgtt tgaggctggg cttttggatg aggccaagtg gctgtttgac
     9841 cattccccta atgtacaggc tgctaaagga attggctata aggaactctt tccttatttc
     9901 cgtggagagc agacctttga ggaagctcgt gagagtctta aacaggcgac ccgtcgtttt
     9961 gccaagcgtc agctgacctg gttccgtaat cgcatgcagg tcacctttta tcagattgga
    10021 gaatctggtg tacaagaccg cattttaagc cagatagagg agtttttaga tgattgaaac
    10081 ggagaaaaaa gaggagcgag tcctgctgat tggtgtggaa ttgcagggta tggacagttt
    10141 tgacctctcc atggaagaat tggctagttt agcgaaaacg gcaggggcag tcgttgtaga
    10201 tagctacaga caaaaacgtg aaaaatatga ttccaagacc ttcgtcggct ctggtaagtt
    10261 ggaagagatt gcgcttatgg tggatgcaga agaaatcact actgtcatcg tcaacaatcg
    10321 tctgacccca aggcagaatg tcaatctaga ggaagttctc ggtgttaagg tcattgaccg
    10381 tatgcagttg attttggata tctttgccat gcgggctcga agccatgaag ggaagctcca
    10441 agtccaccta gcccaattca aatacctctt gcctcgcttg gttggtcagg ggattatgct
    10501 cagccgtcag gcagggggaa ttggttcccg tggtcctggt gaaagccaac tggagctgaa
    10561 ccgtcgtagc gttcgcaatc aaatcacgga tatcgagcgc cagcttaagg tggttgagaa
    10621 aaatcgtgcg actgtcagag aaaaacgttt ggagtctagc acttttaaga ttggtttgat
    10681 tggttatact aatgctggga aatcaactat catgaacatc ttgaccagta agacccagta
    10741 tgaagcagat gagctctttg cgactctgga tgcgacaacc aagagtattc atctgggagg
    10801 caatctccaa gtaactttga cagataccgt tggctttatc caagatttgc cgacagagtt
    10861 ggtgtccagt ttcaagtcaa ccttggaaga aagcaagcat gtggaccttc tggttcatgt
    10921 tatcgatgct agcaatcctt accacgagga gcatgaaaaa acggttctct ccatcatgaa
    10981 agacctggac atggaagata ttcctcactt gacgctttat aataaagcgg atttggtgga
    11041 ggatttcacg cctacccaaa cgccatatac cctcatttct gccaagtctg aggacagtcg
    11101 tgaaaacttg caagcattat tgctagataa gattaaggaa atttttgaag catttaccct
    11161 gcgagtgcct ttttcaaagt cctacaagat tcatgattta gagagtgttg caattctgga
    11221 agaacgtgat tatcaggaag acggcgaagt gattacaggc tacatttccg agaaaaataa
    11281 atggaggtta gaagaatttt atgactgata ttaaaacttt ggctctaaag tatggaggtt
    11341 atacaagtct ggacaaggtc tatctggatc agcttctagc tggtaaaaca gatcaggagc
    11401 agttaacact tattacacct ccgccaagtg ttgttaatgc ctactttgca gaactctatc
    11461 agaaaaagag tcctcaggct gcgacggatt attttgcaga actcagtcag gaactgaatc
    11521 tttacaatac tgagccaagt ttcaccctag aaaataagcc ttttattcgg cttaatctgt
    11581 ctggtaaatc ctttggtttt tgttatgaga gtgacggcct tggtcggatt ttctttgaaa
    11641 atgaggagaa aatctcggat gacttgctct ttgaaattgc gcaaattttc ccccatcaat
    11701 tagtctttga agagtctggt aagatttaca tgaagcctgt cgaggacgag gaagttatca
    11761 gcctagaaag tctcacagct ttgactgatt tggaaagatt ggctgatggt cgaaaacgtc
    11821 tcaaaggcta cagccaagag gatttattgc aagaagctgc tgctttttct ggcaaacgct
    11881 atttccgatc ggaaaaccgc acagccatgt tatatattga ttaattagaa agtatcgaat
    11941 ggatattcaa tttttaggaa cgggggctgg tcagccctct aaagcccgca acgtttcaag
    12001 tctcgccctg aaacttttgg atgagattaa cgaagtttgg ctctttgact gtggagaagg
    12061 tacgcaaaat cgcattctgg aaaccacaat tcgaccacgt aaggtcagca aaatctttat
    12121 tacccatctg catggagacc acatttttgg tttgccaggt ttcctttcta gccgtgcctt
    12181 tcaggccaat gaagagcaga cagatttgga aatctacgga cctcaaggaa tcaagtcatt
    12241 tgtcttaacc agccttcgtg tgtcaggttc tcgtctgccc taccgcattc atttccatga
    12301 gtttgaccaa gattctctag gtaaaattct tgaaaccgat aaattcactg tgtatgcaga
    12361 ggagctggac cacactattt tctgtgttgg ctatcgtgtc atgcaaaagg atctagaagg
    12421 gacgctggat gctgaaaaac tcaaggctgc tggtgttccg ttcggcccgc tttttggtaa
    12481 aatcaaaaat ggccaggatc ttgttttgga agacggaact gaaatcaagg cagcagacta
    12541 tatctcagcg ccacgtccag gtaagattat cactatttta ggagacactc gaaaaacgga
    12601 tgccagtgtg cgtctggctg tcaatgcaga tgtcctagtt catgagtcca cttatggcaa
    12661 gggtgatgaa aaaattgctc gtaaccatgg tcactcaact aatatgcaag ctgcacaagt
    12721 agcggtagaa gcaggtgcca aacgcctcct actcaaccat atcagtgccc gtttcctctc
    12781 aaaagatatt agcaaactca agaaagacgc tgccacaatt tttgaaaatg tccatgtggt
    12841 caaagacttg gaagaagtgg aaatctagca gtcacagaaa ggataagtat gcctactatt
    12901 ctcattaccg gagctagcgg tggtctagct caagaaatgg tcaaactcct gcccaatgac
    12961 caactcatct tgcttggtag aaataaggaa aaattagccc aactctacgg aaattattcc
    13021 catgcagaat tgattgaaat tgatattacc gacgattcag ccctagaagc tctggtaact
    13081 gatctttatc tccgctatgg caagattgat gtcttgatta acaacgctgg ttacgggatt
    13141 tttgagggat ttgaccagat tgctgataaa gatattcacc agatgtttga ggtcaatacc
    13201 tttgccctga tgaatctgtc tcgtcacctt gcggctcgta tgaaggaaag cagcaaaggg
    13261 catatcatca acatcgtcag catggcaggt ctaatagcta ctggcaagtc tagtctttac
    13321 tcagcgacca agtttgcggc tattggtttt tcaaatgctc tgcgactcga acttatgccc
    13381 tatggagtct atgtgacaac agtcaatcca ggtccaatcc gaacaggatt ttttgaccaa
    13441 gctgacccag atggaactta tcttaaatcg gttgaccgct tcctcttaga ggcagatgca
    13501 gtggctaaaa agattgtcaa gattataggc aaaaataaac gagaactcaa tctcccgatt
    13561 ttgttgaacc tagcccataa gttttatact ctctttccca agctagctga taagttggca
    13621 ggggaaactt ttaattataa gtaaaaagaa ccaatgtgca ggttgttgct agcctacata
    13681 ttggttctta tcatttctca actatcaaac tgaacttctt ctaggagata gtcgataaag
    13741 cgttcgccca tcttagatag gctggttttc tcatgctgga tatagaccag ctcaatcggg
    13801 tcatcaatat ccagtgggat agaaacgata ttgtctccgt ttaggttgct gttcaaaatc
    13861 cctgtcgcaa tggtataacc atccaaacca atcaagagat taaagagggt ggcacggtca
    13921 ctgaccacaa tggatttctt gtggtgttct tgagaaagaa tctcttctga aaagtagaag
    13981 gagttgtgcg tcccttggtc atagctgagg taagggaaat tctccaaatc agacagtttc
    14041 accttgtctt tctttgccag agggttggtc ttgctgacaa agatatgcgg ttgcgctgtg
    14101 aagagatggt gggatagcag gtgattgtca tccagcatct tggttaaaac atcacggttg
    14161 tagctgttca aaaataggac accgacctca ctacggaaat tcttgacgtc gtcaataatc
    14221 tcccaagtcc gagtttcacg aaggaagagt tcgtatttct ccatatcgct tttcttgagc
    14281 aaagagacaa aggcattgac cacaaaggca tagtgttgag acgaaacgct aaagagttcg
    14341 cggtgggcga caggattttt atagcgttcc tccagaagct gggtctgctc gacaacctga
    14401 cgggcatagg agagaaactc catcccatca cgggtcaagg tgattccctt gggattgcgg
    14461 ataaagatct caatgcccat ttcattttcc aaatctcgca ctgcattgga gagacttggc
    14521 tgagtgataa agagttgctt ggctgcctca ttcatggagc cagtttcgac gattttgata
    14581 atataatgta attgttgaat tctcatgttt ttattgtacc atacttgcct tagaatcgct
    14641 aaagaagata ggaaaataag gagcattgtg tgagtctctt cttgaaaaaa acacaaaatt
    14701 ttgctagaat gagtcttatg aaaacattct atgatgtgca gcaattcctc aaacgatttg
    14761 gtattattgt ttacatggga aaacgcttat atgatattga actgatgaag ttggaactat
    14821 ctcggattta cgatgcaggg ttgatggata aattagacta tctagaggca gaagcagttc
    14881 ttcgcagaga gcacaaggta gaattggatt atattgagaa aaatggagaa aagaactaat
    14941 ggttacttgg attttgtggg cacttatact agcaatgttg gcgtggatgg gctttaacta
    15001 tcttcgtatt cgccgtgcgg ctaaaattgt ggacaatgag gagtttgaag ccttgattcg
    15061 tacgggtcaa ttgattgatt tgcgcgaccc agcagaattc cacagaaaac atatccttgg
    15121 tgcacgcaat attccttcaa gtcagttgaa aactagtctt gcagcccttc gtaaagataa
    15181 acctgtcctt ctctacgaaa accaacgtgc gcaacgagtt acaaatgcag ctctttactt
    15241 gaaaaaacaa ggtttttctg agatttatat cctttcttat ggcttggatt cttggaaagg
    15301 gaaagtgaag actagctaac cttatttcca aattagtcga atgataggat gaagctattg
    15361 ttttatagta taattaattt gtataaaatt taaggagttc ttagaacatg aaagaaaaga
    15421 agaaaaatcc actttttgtg ggtatcttgt cgattattct tggtttgtta tttccaattg
    15481 taggcctgat tttgggtatc ataggattgg tcttggctat ttcataccaa aaagagtcac
    15541 aattagacta taaaatagaa aagattctta atatctaagg aattgtgatt tctgtagtta
    15601 actggattgt agcaatcgcc ttaatttttc ggtaaataaa agaaaaaagc tttagtttta
    15661 aagctttttt tgttttatcg actcatctct aaatagtttt taatgatttg taactctttt
    15721 tggttcaaag ggcggtagtt accttctgct aaatctgggt tcaatgtgaa gtccccaaat
    15781 tggattcttt tgaggctagt caccttaaca ccaaccgaga ggaacatttt cttgatttga
    15841 tgaaattttc cttctgaaat ggtgatagag gcttgactga gggagggact tgcagataga
    15901 atctctagtt ttgcgggttt acagacagta ccatctaaaa agacaattcc cttttgaaag
    15961 gcttggatat ggtcaggtgt tagaagtcca ttaacctgga cttggtaagt cttatcgaca
    16021 tgatattggg gatggaggag ctgaaagccc aagggaccgt tatcggtcaa gaggaggagt
    16081 cccgttgtat ctcggtccag tcggccaacg gcatagagct tgtcagactg gatgtcagat
    16141 ggaagcaggt ccatgacggt cggaagttcc ttgtctttgt tggctgtaac gacaccagca
    16201 ggtttatgaa gcataagata ggtgtgttca tagccttgaa tgattcgatc ctgaaaaagg
    16261 agttcttgta gtcctgtatc gatattttga gctagggagc gggctgggca accatcgact
    16321 agaatttccc ctctgaggag tgcttgcttc atggcctttc ggctgatttt ttcttgggct
    16381 aataaattat ctaaacgcat actgtgccta tcttatcata agtcgctcgc tttgaaaagg
    16441 cttgacgtga aaagaaaagc agagtgaaaa catttacact tgcttgagtt atgttattta
    16501 cttgaaatta tggtataatc gttcagttag aaaataaatt ttgaatatta tagaggaaat
    16561 catgacaaaa ttaagagaag atatccgtaa cattgcgatt atcgcccacg ttgaccacgg
    16621 taaaacaacc ctggttgacg aattattgaa acaatcagaa acgcttgatg cacgtactga
    16681 attggcagag cgtgctatgg actcaaacga tatcgaaaaa gagcgtggga ttaccatcct
    16741 tgctaaaaat actgccgttg cttacaacgg aactcgtatc aacattatgg acacaccagg
    16801 acacgcggac tttggtggag aagttgagcg tatcatgaaa atggttgacg gtgttgtctt
    16861 ggtcgtagat gcctatgaag gaaccatgcc acaaactcgt ttcgtattga aaaaagcctt
    16921 ggaacaagac cttgtcccaa tcgtggttgt taacaaaatc gataagccat cagctcgtcc
    16981 agcagaagta gtggatgaag tcttggaact tttcatcgag cttggtgcag atgacgacca
    17041 gcttgatttc ccagtggttt atgcttcagc gatcaacgga acttcttcat tgtcagatga
    17101 tccagctgac caagaagcga ctatggcacc aatctttgac acgattatcg accatatccc
    17161 agctccagta gataactcag atgagccttt gcagttccaa gtgtcgcttt tggactacaa
    17221 tgacttcgtt ggacgtatcg gtatcggtcg tgtcttccgt ggtacagtta aggttgggga
    17281 ccaagttacc ctttctaaac ttgacggtac aactaaaaac ttccgtgtta caaaactctt
    17341 cggtttcttt ggtttggaac gtcgtgaaat ccaagaagcc aaagcgggtg acttgattgc
    17401 cgtttcaggt atggaagaca tctttgtcgg tgaaaccatc actccgacag atgcagtaga
    17461 agctcttcca atcctacaca tcgatgagcc aactcttcaa atgactttct tggtcaacaa
    17521 ctcaccattt gctggtaaag aaggtaaatg ggtaacttct cgtaaggtgg aagaacgctt
    17581 gcaggcagaa ttgcaaacag acgtttccct tcgtgttgac ccaactgatt caccagataa
    17641 atggactgtt tcaggacgtg gagaattgca cttgtcaatc cttatcgaaa caatgcgtcg
    17701 tgagggctat gaacttcaag tatctcgtcc agaagttatc gtaaaagaaa tcgacggtgt
    17761 taaatgtgaa ccatttgaac gtgtacaaat cgacactcca gaagaatacc aagggtctgt
    17821 tatccaaagc ctttctgaac gtaaaggtga aatgttggat atgatttcaa ctggtaatgg
    17881 tcaaactcgt ttggtcttcc ttgttccagc gcgtggtttg attggatact caactgagtt
    17941 cttgtcaatg actcgtggtt acggtatcat gaaccatacc ttcgaccagt acttgccatt
    18001 gattccaggg gaaattggtg gacgtcaccg tggtgccctt gtttctatcg atgctggtaa
    18061 ggctacaact tactcaatca tgtctatcga agaacgtggt acgatctttg tcaacccagg
    18121 tactgaggtt tatgaaggaa tgatcatcgg cgaaaactct cgtgaaaatg acttgacagt
    18181 taacatcacg aaggcaaaac aaatgaccaa cgttcgttca gctactaagg accaaacagc
    18241 tgttatcaag acgcctcgta tcttgacact tgaagagtct cttgagttct tgaacgacga
    18301 tgagtacatg gaagtaacgc ctgagtctat ccgtttgcgt aaacaaatcc ttaacaaagc
    18361 agagcgtgag aaagctaaca agaagaaaaa atcagctgaa taagagctag aaagagagaa
    18421 agatggtcta tttagtccta ggaattttac tgctcctact ctatgtattt gcgacaccag
    18481 aaagcattaa agggactgtc aatatcgtcg ctatggtatg tattttagtg gcactcttga
    18541 ttttattggt tctatctttt ctgaaaattt ttcaattacc aacagaaata ttcctagcaa
    18601 tagccatgtt gatcctagct tactttagtg tgagagacat cacactcatg ccagtcaaaa
    18661 aaagtaaaag aagataaaaa agagagtttc ggctctcttt ttgctaggaa ttttacaata
    18721 gtttgaattg ctttttagtt aacaccatct cttttacttg gatagtatga atgggaaaaa
    18781 cttgaataaa attcgttaat ggcatctatt ttatatttgg ttagta
//
LOCUS       DAVLGK010000042        18810 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLGK010000042 DAVLGK010000000
VERSION     DAVLGK010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18810
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.042"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(278..1084)
                     /gene="yidA"
                     /locus_tag="VXE01_001686"
     CDS             complement(278..1084)
                     /gene="yidA"
                     /locus_tag="VXE01_001686"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV0750550.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(1097..2401)
                     /locus_tag="VXE01_001687"
     CDS             complement(1097..2401)
                     /locus_tag="VXE01_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0750551.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            2473..2850
                     /locus_tag="VXE01_001688"
     CDS             2473..2850
                     /locus_tag="VXE01_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV0750552.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKRDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYILTPMGMQEFTIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            2941..3273
                     /locus_tag="VXE01_001689"
     CDS             2941..3273
                     /locus_tag="VXE01_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV0750553.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            3285..4856
                     /gene="ffh"
                     /locus_tag="VXE01_001690"
     CDS             3285..4856
                     /gene="ffh"
                     /locus_tag="VXE01_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV0750554.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(5051..6334)
                     /locus_tag="VXE01_001691"
     CDS             complement(5051..6334)
                     /locus_tag="VXE01_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV0750555.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSIALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPSIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6686..7399)
                     /gene="rsmG"
                     /locus_tag="VXE01_001692"
     CDS             complement(6686..7399)
                     /gene="rsmG"
                     /locus_tag="VXE01_001692"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV0750556.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            7493..8053
                     /locus_tag="VXE01_001693"
     CDS             7493..8053
                     /locus_tag="VXE01_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV0750557.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            8055..8954
                     /gene="htpX"
                     /locus_tag="VXE01_001694"
     CDS             8055..8954
                     /gene="htpX"
                     /locus_tag="VXE01_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV0750558.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRIFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(8998..10557)
                     /locus_tag="VXE01_001695"
     CDS             complement(8998..10557)
                     /locus_tag="VXE01_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0750559.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRLLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(10796..11113)
                     /locus_tag="VXE01_001696"
     CDS             complement(10796..11113)
                     /locus_tag="VXE01_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0750560.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYDHVKHVLSLYGPV
                     FEF"
     gene            11283..11825
                     /locus_tag="VXE01_001697"
     CDS             11283..11825
                     /locus_tag="VXE01_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV0750561.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            11825..12454
                     /gene="nth"
                     /locus_tag="VXE01_001698"
     CDS             11825..12454
                     /gene="nth"
                     /locus_tag="VXE01_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV0750562.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            12665..13186
                     /gene="pyrR"
                     /locus_tag="VXE01_001699"
     CDS             12665..13186
                     /gene="pyrR"
                     /locus_tag="VXE01_001699"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV0750563.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            13205..14128
                     /locus_tag="VXE01_001700"
     CDS             13205..14128
                     /locus_tag="VXE01_001700"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV0750564.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            14178..15257
                     /gene="carA"
                     /locus_tag="VXE01_001701"
     CDS             14178..15257
                     /gene="carA"
                     /locus_tag="VXE01_001701"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV0750565.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            15570..18746
                     /gene="carB"
                     /locus_tag="VXE01_001702"
     CDS             15570..18746
                     /gene="carB"
                     /locus_tag="VXE01_001702"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV0750566.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         5476 a         3622 c         4219 g         5493 t
ORIGIN      
        1 atcctaattt gtataattga ttgtgtgtag attcagggtc aatttgaaga gagtatttaa
       61 aatatcttgg gaaattataa tttctccctg ttttttgagt ccaatctatg agtatgagtt
      121 gcccaggagt aaggccacat tctaattcgt ttaggtaaaa attgttacaa tcagaatttg
      181 tgtctctatt atgattattt tgttttaaat taaatagttt gctaaaaaaa ttcattggat
      241 tttattgcta atcaattctt attgaaaaat gatactttta cagtacccat gttcggatgg
      301 cgtgggcaac gccggattcg tcatttgttt tcgtgatgta tttggcgatt tttttgattt
      361 ctggatttcc gttttccatg actacagggt tgccaacgac ttccagcatg gcacggtcat
      421 tttcttcgtc tccgatagcc atggtttcat ctttggttaa tcctagtttt tcagccaagt
      481 gagtaatagc tgaacccttg tctacattct ttttaaggag ttcgaggtag aaaggagcag
      541 atttgttgat ggagtagcgt tcgtaaaatt ctgctggtat cttttcaatc gcagcatcga
      601 gaatctctgg ttcatcaata aacatacatt tgacgatttc cttgccagcc atttcttcag
      661 gagtgcggta gaagataggc atgctgacga gggttgattc gtgtacagtg tatgttccga
      721 tattgcgatt tgcagtatag ataccgtcct tagtaatagc atgcatgtga acaccaagct
      781 tgcgactgag aaattccata tccagataat cctcataggt caaggattcg ctgataatct
      841 catggccagt agcagtttct tggacaaggg caccgttgaa ggtcaccaca tagtcacctt
      901 ggtctctcaa ctgcaagtcg tccagaagtt tggcaacacc tgcgatgggg cggccagttg
      961 caatcacgac tttgacacca gcttctttgg catcttggat ggcagaaaag acttcaggag
     1021 tgatttcctt ttggctgttg actagggttc cgtcaatatc gacggcgatt agtttaatac
     1081 tcataaattt cctcttttag tttttatttg gggtaaaatg atcgttctca atcaagtgta
     1141 aaaattgctg ggtgatgctt gcgaagatgc tgttttggtc taacatttct ttcgggaaat
     1201 aaaagcgatt atctccgtgg cgacttccag caagggattg gacgataggg gacaggctag
     1261 agagttctgc cagttctcca tttttttgta aaatctcaat ctgtgtcctt ggattttcag
     1321 attcgggacg gtaaatatca taagggaggt caaagttctt atgaatggca gtatagtagt
     1381 cgggatcaaa gccgatgtcc tcaaccaatt ttctcatgct agcgagttgg tcttggtctt
     1441 cttgtgaaaa ggtaatggat ttaaagacct tgcggttgac aaagcgttgt gacaagtctg
     1501 cgagaatctt gtcaggactg gtcatccaga gttgaaagta ggtattcatc acaccatcat
     1561 ctagagccag atagtcagtc aaggtcacat ttttttcaaa gaaaggcagg aggtgtggag
     1621 aagttcgtgc aaagaagtcc ttgtcttcag gatagagttc cttggcgcgt ttgaggagat
     1681 tctgcaggag aacttccatg gcgcgtgttg cggggtggaa ataaacctgc atgtacatct
     1741 ggtagcgact gaggacgtag tcttcgatgg cgtgcatgcc attgcgctga aaggcgatac
     1801 cattttcgat aggacgaatg actcggagga tgcgagtcag gtcaaattcc ccataggatg
     1861 ctcctgtaaa ataggagtcg cgcaagagat agtccatgcg atctgcgtca atctgactag
     1921 aaatgagctg cacgacctgc ttattaggat aggtatggtc aatgacactg gccacctttt
     1981 ctgggaaatc gggcgctact tgtagcaaga cttggtgaat ctctgtctca ggattttgaa
     2041 taatctcctg agtaatggct tcatggtctg tatcaaagag atgttcaaaa gtatgggagt
     2101 aggcgccatg cccaaggtca tgtaggagag cagcggtcat ggtcaagaga gactcggcag
     2161 gattccattc ctcaggatat ttttcttcaa aaatttctgt gatacgtcgt gcaatctcat
     2221 agactcccag acagtgagag aagcgactat gctctccacc gtggaaggta taactggaag
     2281 tccctagttg cttgatccgg cgcaaacgtt gaaattcttt tgtattaatc aagtcataga
     2341 tgatttgatt attgacatgg atgtagttgt gaactgggtc acggaatact ttttcgttca
     2401 tatgaccatt atagcaaaat cctgctcttt ttggtaaaat agtaggacaa gagacaagaa
     2461 agaggacctg atgtgaagat tcggatgcga aatacaattc agtttgatga gcagttggaa
     2521 gtgattgacc agctttatga tgtggaagtg catgaaaaaa gagattatag ctacctgctt
     2581 ttctataatg aggaaaagga aaaagtagtg attaaatttc atggtcaaga acttgtgatg
     2641 agccgatttt ctaatcccaa gaccattatg cgctttctaa aggatagcga tagtttagcc
     2701 tatattctta cacctatggg catgcaggag tttaccatcc aaacgagcca ttatcaagtt
     2761 gataggcaaa agattgaact agattatcaa ctacaaaatc aagagggaca tccctttgcc
     2821 agctatcaat tggaaattac ttggggctag gctcatgtct ttttcaaatt tagctatcta
     2881 tcttcttgga tcggcttcct agtgtggtag attaggctaa tttttggtat aataaaagtt
     2941 atggaaatcg aaaaaaccaa tcgtatgaat gcgctctttg aattttatgc ggcgcttttg
     3001 acagataagc aaatgaatta tatcgagctc tactacgctg atgattacag ccttgctgaa
     3061 attgccgagg agttcggtgt cagtcgtcag gctgtctatg acaatatcaa gcgaacagaa
     3121 aagattctgg aagattatga gatgaaattg catatgtact cggactatat tgtccgcagt
     3181 cagatttttg atcagatttt ggagcgctat cccaaggata actttctgca ggagcagata
     3241 gaaattttaa caagcattga taatagagaa taagaggaag aaaaatggca tttgaaagtt
     3301 taacagaacg tttgcagaac gtctttaaaa atctacgtaa aaaaggaaaa atctctgaat
     3361 ctgatgtcca agaggcaacc aaagaaattc gcttggcctt gctcgaggcc gacgttgcct
     3421 tgcctgttgt aaaggacttt atcaagaaag ttcgtgagcg tgcagtcggg catgaggtca
     3481 ttgatacact taatcctgcg caacagatta ttaaaatcgt tgatgaggaa ctgacagccg
     3541 ttttaggttc tgatacggca gaaattatca agtcacctaa gattccaacc atcatcatga
     3601 tggttggttt acaaggggct ggtaaaacaa cctttgctgg taaattggcc aacaaactca
     3661 agaaagaaga aaatgctcgt cctttgatga ttgcggcgga tatttatcgt cctgctgcca
     3721 ttgatcagct gaagacactg ggacaacaga ttgatgtgcc ggttttcgct cttgggacag
     3781 aggttccagc tgttgagatt gtacgtcaag gtttggagca agctcaaact aatcataacg
     3841 actatgtctt gattgatact gcgggtcgtt tgcagattga tgagctcctc atgaatgagc
     3901 ttcgtgatgt gaaagcattg gctcaaccaa atgaaatctt gcttgtcgtt gatgctatga
     3961 ttggtcagga agcagccaat gttgcgcgtg agtttaatgc tcagttggaa gtgactgggg
     4021 tcatccttac caagattgat ggcgatactc gtggtggtgc tgctctgtct gttcgtcaca
     4081 ttactggaaa accaatcaag ttcactggta caggtgaaaa gattacggac attgaaacct
     4141 tccacccaga ccgcatgtct agccgtatcc ttggcatggg ggatatgctc actttgattg
     4201 agaaagcttc tcaggaatac gatgaacaaa aagcccttga aatggctgag aagatgcgcg
     4261 aaaacacctt tgattttaat gatttcatcg atcaattaga tcaggtgcaa aatatggggc
     4321 cgatggaaga cttgctcaag atgattccag gtatggccaa caatccagcc cttcaaaaca
     4381 tgaaggtgga tgaacgccag attgctcgta aacgtgccat tgtgtcttcg atgacacctg
     4441 aagagcgtga aaacccagat ttgttaaatc caagccgtcg ccgtcgtatt gctgctggtt
     4501 ctggaaatac attcgtcgaa gtcaataaat tcatcaagga ctttaaccag gctaaacagc
     4561 tcatgcaggg tgttatgtct ggggatatga ataaaatgat gaagcaaatg gggattaatc
     4621 caaataacct tcctaaaaat atgccaaata tgggaggaat ggatatgtct gcccttgaag
     4681 gaatgatggg acaaggcggt atgcctgact tatcagctct cggaggagca ggaatgccag
     4741 atatgagcca gatgtttggt ggcggtttga aaggtaaaat tggtgaattt gccatgaaac
     4801 agtccatgaa acgtatggct aacaaaatga agaaagcgaa gaagaaacgc aagtaagaca
     4861 agagattgat gcaaatctca tttgatgaga aaataaagaa aaaatttcta tgataaaacg
     4921 tacagtatca aggttttaga atatctgata ttatacgttt tttgatttta ataattttgt
     4981 taagacactt ttattatggt atgcgaaaaa tccactcagc tgtctgagtg gattaggtgt
     5041 atttagactc ttagtcttta ttttcgtatg gcaagatcaa gttcaagatg attcctgtca
     5101 tggctgaaag ggcagtacct gaaagtgtaa ctggaccaag tttaaggata gctcctccaa
     5161 gtccaagaac caacatagca cttgcgatga tgaggtttcg catttgagcg aaatcaacac
     5221 gttctttaat caagactttc aaaccattgc tggcgataac cccatagaga aggattgaca
     5281 taccaccaag tacagcgttt ggaatagttg aaatcaaggc agtgaattta ccaaggaagc
     5341 tgagggcaat cgcgatgaag gcagcgttac ggataactga gacagaagcg atacgagtca
     5401 taccgataac ccctgtattt tctccgtaag ttgtattggc tggtccacca aggaaggcag
     5461 aaacagaagt tgcgataccg tcaccaagaa gagtacggtg aagacctggt tcttttaaga
     5521 attgacgacc acagatttga cccaaaacag tatggtctcc gatatgttca gaaattgtta
     5581 cgatagcgat tggcaagata gcgatggctt ctggaccaaa gtaaagattg tactctttaa
     5641 aggcaccacc tgtgctaaat ggcaagtaga aaccaggaat ttcgaaccag ttggctttaa
     5701 gaactggtgt aaagtcaacc aagccaagag ttagtgcgaa aaggtaacca ccgataatgg
     5761 caaagaggaa tggaatgatt cgtaggaagc cttttccttt tgtattgata aaggcagcaa
     5821 ttaggaaagt aacaacggct accagagcat ttttccaatt tccgtctgct acaagacctg
     5881 cattggtaac agctgaacct gcaagtccaa gaccgataac gatgatcata ggaccgataa
     5941 tgattgatgg caagagttta tcaatccatt ttgttcctac aaatcggatg ctggtagcaa
     6001 caaggacata gaccaaacca gtcaagataa cccctgtttg ggcagcagat acatcccccc
     6061 ccatttcttt catagccagt gacatagctg tgataaaggc aaatgaagaa cctagataaa
     6121 ctggaacttt aaaaccagta gcaatcatgt agatgagtgt tccaacacct gaagcaaaaa
     6181 gggcaataga tacaggcatt cccaaaatca atggtaccaa gatggtcgca ccaaacatgg
     6241 cgaaaacgtg ttggaaacta aggagaattc cttttccatc cgaaggacgt tggtcaacgt
     6301 ctagtaacaa atcaacagtt gattcttgtt tcatataaac ctcacttttg ggcatcagaa
     6361 aagagcccat tattttacag caataggccc tcagagtaag acttctctaa aatctagact
     6421 ttaaagagtt tcaaatattt ctgcgtcttc gtcacctcac gggatgacat taaaaacctt
     6481 tgcttaggat agtatagcag aaaaaaatga ttttgtaaat cattttttcc cgagcctaga
     6541 aataaaagag cgaggctgat tttgtaaatc attttttccc gagcctagaa ataaaagagc
     6601 gaggctgatt ttgtaaatca ttttttcccg agcctaaaaa taagagagcg aggttgattt
     6661 tgtaaatatt tttttactta aaaatttaaa gcgggcgttt atttggcata ccagccttac
     6721 gtggatattt atttggtgtt tcttttttct tttctaccac tgtgatgtaa cgcggatctc
     6781 tatttggtag ggcgtagctg agattgtctt cgactttact aaaaaggaga ttgagggcat
     6841 tcttagcttc taacaactcc tcaggcgcat tgctggcctt gagtgccaat agttttccac
     6901 caaccttaag gtagggaata gtcaattcag ataggacctg catacgggca accgcacgag
     6961 ctgttacaaa atcatattga gcacggaagt tcttgtcttg ggcaaaatct tcggcacgtc
     7021 cgtggtagaa atgaactccg ttcaaatcca gttcttgagc caagagttgt aggaagttga
     7081 tgcgcttatt gagtgaatca ataatggtca catctaactc cggatagaga attttcattg
     7141 gtagactagg aaatcctgcc ccagccccga tatcaagaag tttgatagtt tcattgggaa
     7201 tcaaaccttg aagaatgggt gcaatcgaat cgtaaaaatg tttgagataa acttcttcct
     7261 tgtccgtaat cgccgtcaaa ttaatcttct cattccactc gaccaagagc tcaaaataac
     7321 gttcaaattg ttctttttgc tggtccgaaa gtggaagatt ctgctcggca agcaagttgt
     7381 aaaatgtttt tggtttcata gttatttcct tctttagtat catcttattt taccacaatc
     7441 atagaaaatt tgatatactg gtactaatct aaaagcagaa aggacttata ttatgacttg
     7501 gattattctt ggagttttag ctcttgttgt tatttttgtg attgttagct ataacggttt
     7561 ggttaaaaat cgtatgcaaa ccaaggaggc ttggagtcag attgatgttc agttgaaacg
     7621 tcgcaatgat ctcttgccaa acttgattga gactgtaaaa ggttatgcca aatatgaagg
     7681 ttctaccctt gaaaaggtgg cagaactacg taaccaagtg gcggcagcga cttcaccagc
     7741 agaagctatg aaagccagtg atgccctcac tcgtcaggtt tcaggtattt ttgcagttgc
     7801 agaaagctat ccagatttga aagctagtgc taactttgtt aaattgcaag aggagttgac
     7861 aaacacagaa aataaaattt cttactctcg tcaactctat aacagtgttg tcagcaacta
     7921 caatgtaaaa ttagaaactt tcccgagcaa tattatcgct ggaatgtttg gatttaaagc
     7981 ggcagatttc cttcaaacac ctgaagagga aaagtcggtt cctaaagttg attttagcgg
     8041 tttaggtgac taagatgttg tttgatcaaa ttgcaagcaa taaacgaaaa acctggattt
     8101 tgttgctggt atttttccta ctcttagctc ttgttggtta tgcggttggt tatctcttta
     8161 taagatctgg acttggtggt ttggttatcg cactgattat cggctttatc tacgctttgt
     8221 ctatgatttt tcaatcgaca gagattgtca tgtccatgaa tggagcgcgt gaggtggatg
     8281 agcaaacggc accagacctc taccatgtag tggaagatat ggctctggtc gctcagattc
     8341 ctatgccccg tattttcatt attgatgatc cagccttaaa tgcctttgcg acaggttcta
     8401 atcctcaaaa tgcggctgtt gctgcgactt caggtctact agctatcatg aatcgtgaag
     8461 aactagaagc tgttatggga catgaagtca gtcatattcg taattatgat atccgtattt
     8521 cgactattgc agttgccctt gctagtgcta tcaccatgct ttctagtatg gcaggtcgta
     8581 tgatgtggtg gggtggagca ggtcgcagac gaagtgatga tgaccgagat ggaaatggtc
     8641 ttgaaatcat tatgctagtg gtttccctac tagctattgt actggcacct ctcgctgcaa
     8701 ccttggttca gctcgctatt tctcgtcaga gggaatttct ggcagatgca tctagtgtcg
     8761 agctgactcg caatccccag ggaatgatta atgccctaga taagttggac aatagcaaac
     8821 ctatgagtcg ccacgtcgat gatgctagca gtgcccttta tatcaatgat cctaagaaag
     8881 gtggggggtt ccaaaaactc ttttataccc acccacctat ctcagaacgg attgaacgtt
     8941 taaaacagat gtaaaagaat ccagaggtcg tctctggatt tttgctatgt tgcaaattta
     9001 taaatcttct aaattaacta gcttcaaacc gtgttctgtc atgcgataga tgatcgagca
     9061 gacttctttt aataaacgac ggtcatgcga aacagtgatg agaccgcctg gataggtagc
     9121 aaagagtttt ctgatttggg gttgagaagt gggagaaaag tttcgtgtgg gttcatccag
     9181 caggagaaag tttggtttgc gcaggactaa atccaaaagc aggagttttc cctgttgtcc
     9241 gccagataag gagcgaattt gatgctgcat ttctggataa ctgaaattga gactagctag
     9301 gtgagattgg attttctgta gttcctcttt ttccccagtt ttactgagat aggctattgg
     9361 ggataaatcc aattgcagtt ttttgtggta atcttgtggc ataaaaccaa gtgaaatctc
     9421 tcttttatca ttcagaagtc tctgtaactt ggctaacaga gttgatttcc caacaccatt
     9481 tggcccgata ataccgattt tttcttggcc acggacagtt agttgtagtt tttgaaccaa
     9541 aactcggtcg tcaatggaca aattttcttt ttccagttgg actaagactt tagaagctgg
     9601 taatggttgg atgtctgaaa agaaaagttg gatttgttcc tcttcaagtg gcttttgagt
     9661 catggactga gctgcctttt cgtagcgttt ttcttgtgag aggacagttt tcatcttttt
     9721 agccaatagg cgaccggcag tactatcttt ggtagctcga agcgcagttt ctacattttg
     9781 cttaactctc cgatgttttt ccatggtttt atcgtaggct ctttggttgt tagcagcttg
     9841 ctgactttgt ttggcaaaat tagcctttct ctgctcacta tagctatcat agtctaaatg
     9901 ctctactagc gtttccgctt ctttacggtg tttgaccagt cgcaagtgaa caatagtgtc
     9961 tgccgtttca gaaagaaagt cttcatcatg ggaaatgaaa ataacggttt gcctggtctt
    10021 ttgaatctgg ccttttagcc aatcaactgt ctcaaggtct aggtcatttg aaggttcatc
    10081 taaaaataga atctcaaagg gtttggctaa ctcatggata agctgaattt tcaaagcttc
    10141 gccccctgat agattgccaa tctcttggtc acttgcgaaa cgattgctat caaaatgcaa
    10201 ttcctccgcc aaacgataga ggatactgta gtctaaatca atagaatcta aaaagaagta
    10261 gtcgtgtaaa gttttctttt ttaggtcctc agggactttt tgaggaatgt aggccagtga
    10321 ctgatagtca gattggatgt ttcccttgat agtgaaatca gacaaagctt cccccattaa
    10381 aattttaagt aaggttgatt tgccatttcc ttcttcacca ataatagcaa ccttttcccc
    10441 gtcttggatg gtcatggtta ggtcagatac aagatctcgt aaatctttgt tttgtgtgat
    10501 ggttagatga ttgattttta tcatatgatt tccctttcta gaatgttcat agtgcataac
    10561 aaaaagctct actttaccta gtagagccca aagtctatgt caaaaaaact ctattaacat
    10621 gccagaaaaa gagcataaaa gagcacacaa aaagagacaa aaacaagatc tactaaataa
    10681 aggttcttta tttgatagac ttagttgttc atgtctccct tacctccgag tattagtatc
    10741 tttatattat acctttaagg aaattttgtc aacagaaaac tggaaattct atgctctaaa
    10801 attcaaaaac aggtccatag agacttagta cgtgtttgac atgatcgtaa tggaatttat
    10861 catagtttcg ccaagcagtg cgtgcttgat cgtttagttt taggctaccc agtccaatca
    10921 gaagactggt aggttggtaa aatttctcaa gatcaattaa gatactgttg ttcaactgtt
    10981 ccgttttttt gagctcttgc atagtagtgt ttagcagctc ttgtagtcga atatcatctg
    11041 ccgtaccctg tttacagttt tggtagcttt tatttaactt ggataggagt tgaatgagtt
    11101 tcttgtcttc catgtgagca tcctccttga tctgatgtac tctttcccta tagtatagca
    11161 ctaaaaaata aaactatcat agtaaatatg ttaaaatttt gaattttaat tacaaagttt
    11221 ggtgtgctga tttgtagcct tttcatggta taatcaagag agtaaatctt tatggaggaa
    11281 gtatgaaatt aaatattcaa gaaattcgta agcagtctga aggtttgaac tttgaacaaa
    11341 cgttagattt agttgatgac ctgcgtgcac gtaatcaaga aattttagat gtaaaagata
    11401 tccttgcagt tgggaaagta caatatgaag accgtatgta tttcttagat tatcaactat
    11461 cttataccat tgttcttgct tcgagtcgca gtatggagcc agttgagtta gttgaatctt
    11521 atccagtcac ggaagttttc atggaaggcg caactaacca gctagatcaa gaagttttag
    11581 atgatgactt ggtcttgccc atcgaaaatg gggagcttga ccttgctgag agtgtatcag
    11641 acaatatcct gctaaacatt cctatcaagg tcttgacggc tgaagaagaa gctggtcaag
    11701 gatttatctc aggaaatgac tggcaaatca tgacagagga agaataccaa gctcaaaaag
    11761 cagtaaagaa agaagaaaac agtccttttg ctggcttaca aggactattt gacggagatg
    11821 aataatggtc ttgtcaaaaa aacgagcacg aaaggtgcta gaagaaatca ttgccctctt
    11881 cccagatgcc aagcctagtc ttgattttac caatcatttt gaactcctgg ttgcggtcat
    11941 gttatcagcc cagacgacag atgcagcggt aaataaggcc acaccaggtc tctttgttgc
    12001 ctttccaaca ccccaagcta tgtctgtagc gacagagagt gagattgctt cacatatttc
    12061 tcgcttggga ttgtatcgga ataaagctaa attccttaaa aaatgtgccc aacagttact
    12121 agacgatttt gatggtcaag tccctcagac acgtgaagaa ttggagagtt tggcaggtgt
    12181 tggtcgcaag acagccaatg ttgtcatgag tgtaggattt ggaattccag cctttgcagt
    12241 ggatactcat gtggagcgta tttgcaaaca ccacgatatt gtcaaaaaat cagcgacgcc
    12301 acttgaggtg gaaaagcggg tcatggatat cttgccgcct gagcagtggt tagctgccca
    12361 tcaggccatg atttattttg gaagagccat ttgccatcca aaaaatccag agtgtgacca
    12421 gtacccacaa ttatatgatt ttagcaattt gtaagatgct acattgaaac tttttgcttg
    12481 attttaagca tgctttgtgc tatagtaaat gataactaaa tattccttta aacctgtccc
    12541 gtgaggcagg caaggagcgc gataaagtag aagggtgaag tctatactgt gtgcagtagg
    12601 gctcgcttgg ctataaattt caagtctcct tgtttaagga gacttttctt tttggaggtt
    12661 tgtcatgaaa acaaaagaag ttgtagacga attgaccgtc aaacgagcga ttacgcgtat
    12721 tacttatgag attatcgaac gcaacaaaga tttgaataag atcgtcttgg ctggtattaa
    12781 aactcgtggt gtctttattg cccaccgaat ccaagaacgt ttgaagcagt tagaaaatct
    12841 ttcagttcct gttgtggaat tggatactaa acctttccgt gatgatgtta aaagtggaga
    12901 agatacttct ttggtttctg tcgatgtgac agaccgcgaa gttatcttgg tggatgatgt
    12961 gctctataca ggtcgtacca tccgtgctgc tattgataat attgtcggtc atggtcgtcc
    13021 tgcgcgtgtg agtttagcag ttctagtcga tcgtggacat agagaattgc caatccgtcc
    13081 agattacgtt ggaaaaaata tcccaaccag tcgttctgaa gaaatcatcg tagagatgac
    13141 agaacttgat gaccaagaca gagttctgat tactgaagaa gcttagaaag ttaaaggagt
    13201 agccatgtca gaaaatcaac aagcattgaa ccatgtggtg tccatggaag acctcactgt
    13261 cgatcaagta atgaaattga tcaagcgagg aattgagttt aaaaatggag cccagcttcc
    13321 ctatgaagac catccgattg tttccaatct cttctttgag gattctacac ggacacataa
    13381 gtcctttgaa gtcgcagaga ttaaacttgg attggaacga cttgactttg atgtgaagac
    13441 tagctcggtt aataagggtg agacacttta tgacaccatt ttgactctgt ctgctttagg
    13501 agtggatgtc tgtgtgattc gccatccaga ggtcgactac tatagagaat tgattgctag
    13561 tccaacgatt acgacttcca tcatcaatgg tggagatggt tcgggccaac accctagcca
    13621 gagcttgctt gatttgatga ccatttatga ggaatttggc cactttgagg gtcttaaagt
    13681 tgctattgca ggtgacttgg accactcacg cgttgccaaa tccaatatgc agattttgaa
    13741 acgcttggga gctgaactct ttttcgctgg acctgaggaa tggagaagtc aagagtttgc
    13801 agactatgga cagtttgtaa ccattgatga aatcattgat caggttgatg tcatgatgtt
    13861 tctccgtgtg caacacgaac gccatgatag tggagctgta ttttcaaaag aagactacca
    13921 tgcccaacat ggcttgactc aagaacgtta cgatcgtttg aaagaaacag caatcctcat
    13981 gcacccagct ccaatcaatc gtgatgtaga aatagcagac cacttggttg aagcaccaaa
    14041 atcacggatt gtccaacaaa tgaccaatgg tgtctttgtt cgaatggcaa tcttagaatc
    14101 cgtactagcg agtagaaacg ccaactaaaa cacaagacgt taaaagacgc cagtgagcgt
    14161 ccacgagagg tgaaaatatg acaaaaagaa ttctagtatt agaagatggc acagtttttg
    14221 aaggcaaggc cttcggagca gatattgatg taacaggcga aatcgtcttt aatacaggga
    14281 tgaccggcta ccaagaatcc attacagacc agtcttataa tggacaaatc ttgaccttta
    14341 cttatccttt ggtaggaaat tatggtatta atcgtgatga ttatgaatcc attattccaa
    14401 cttgtaaggg agtcgttgtt tttgaagaag cgcgtagagc tagcaactgg cgcaaccaaa
    14461 tgaccttgga tgaatttttg aaagccaaga aaattccagg gatttcagga attgatacgc
    14521 gtgctcttac caagattatc cgtaagcatg gtactatgcg tgcaaccttg acccatgttg
    14581 gggacagtat ggaccatgtg acggaccagc tccaagcaac agttttaccg acagacaata
    14641 tcaaacaggt ttctactaaa acgtcttatc cagctccagg agttggtttg agcgtggtgc
    14701 tagtggactt tggtctcaag cactcaatcc tacgtgaact ttctaaacgc aactgtaacg
    14761 tgacagttgt tccttattcg acaacggctg aagaaattct ccatctcaat cctgacggag
    14821 ttatgttgtc aaatggtcca ggtaacccag aagacgttcc acaagcactc gacatgattc
    14881 gcggtgtaca aggaaaaatt ccaatctttg gtatttgtat gggacaccaa ctctttgcaa
    14941 tggcaaacgg ggctaagacc tataagatga agtttggcca ccgtggattc aaccatgcgg
    15001 tacgtgaaat cgcaacagga cgagtagact tcaccagcca gaaccatggt tatgcagtca
    15061 gccgcgagga tttgccagag cacttgatta ttacccacga agaaatcaat gacaagtcag
    15121 tggaaggtgt gcgccacaga taccaacctg ctttctctgt tcaataccac ccagatgcag
    15181 ctcctgggcc acacgacgct agctacctat ttgacgagtt tatcgagatg atggaagttt
    15241 ttaaacaatc aaactaagaa cgagtaaaag ctcgtcggag aatttatgta actgaacacg
    15301 gacggaaagc tcagaatgta gagaaaccaa cttggattgt caatccttcc ttgatttcct
    15361 aaaattcaat cgctttctat tcgtcctttg tatcttattt aatgtcgccc tgagaggcga
    15421 cgaatagaaa ggagaagggt gctccgtatt tgctgaactg aatacgggct acggacggtg
    15481 ctaaaatagg agttattcct agaactgaca gttcttcgtc ataactccta ttttagcttt
    15541 gtccgcttga cacccttaat atcttatata tgcctaaacg tactgatatt caaaaaatta
    15601 tggtgattgg ttctggtccg attattattg gtcaggctgc tgagtttgac tacgctggga
    15661 ctcaggcttg cttgtcgttg aaagaggaag gttatgaggt tgttttggtt aactcaaatc
    15721 ctgcaaccat catgacggac aaggaaattg ctgacaaggt ttacattgaa ccgattacac
    15781 ttgagtttgt gacacgtatt cttcgtaagg aaggtccaga tgccttgcta ccaacactcg
    15841 gtggtcagac aggtctcaac atggccatgg aattatctaa aaatggtatc ctagacgagc
    15901 ttggcgttga acttctgggt accaaattat ctgccattga ccaagcggag gaccgtgacc
    15961 tctttaaaca attgatggaa gagcttgaac aacccattcc agaatctgaa attgttaaca
    16021 cagtagaaga agcagttgcc tttgcagcga caattggcta cccagtcatc gttcgtccag
    16081 cctttaccct tggtggtact ggtggtggta tgtgtgccaa cgagaaagaa ttgcgtgaaa
    16141 tcactgaaaa tggtttgaaa ttgtcacctg ttacccaatg tttgattgag cgttcgattg
    16201 ccggtttcaa ggaaattgaa tacgaagtga tgcgtgactc agctgacaat gccttggttg
    16261 tttgtaacat ggaaaacttt gacccagttg ggattcacac aggggattcc attgtatttg
    16321 cccctgcgca aaccatgtca gactatgaaa accaaatgct tcgtgatgcg agcttgagca
    16381 ttattcgtgc cctcaagatt gaaggtggat gtaatgttca gctagctctt gatcctaaca
    16441 gcttcaagta ttatgttatc gaagtaaacc ctcgtgtatc acgttcgtca gcccttgctt
    16501 ctaaagcgac aggatatccg attgctaagt tggctgccaa gattgcagta ggtttgacct
    16561 tggatgaggt tataaaccca gttacaggtt caacctatgc catgtttgaa ccagcccttg
    16621 actacgtagt tgctaagatt ccacgtttcc catttgacaa gtttgaaaag ggtgaacgcc
    16681 gtctcggtac acaaatgaag gcgactggag aagtcatggc aatcggtcgt aacatcgagg
    16741 aatctcttct caaggcctgc cgctcccttg aaattggggt gcaccacaat gaaatacctg
    16801 aacttgcagc agtttctgat gatgccttga ttgaaaaggt tgtcaaagcc caagatgacc
    16861 gtctcttcta cgtatcagaa gccattcgtc gtggctacac acctgaagaa attgcagagc
    16921 ttacaaaaat tgatatcttc tatcttgata aactcttgca tatctttgaa attgagcaag
    16981 aattgggtgc tcatccacaa gatttagaag ttttgaaaac agccaaactt aatggttttt
    17041 cagaccgtaa gattgctgaa ctctggggaa cgactgatga taaagttcgc caacttcgct
    17101 tggaaaacaa gattgttcca gtttataaga tggtagacac ttgtgcggca gagttcgact
    17161 ccgaaacgcc atatttctat tcaacctatg gttgggaaaa tgaatctatc agatctgata
    17221 aagaatctgt acttgtccta ggttcaggtc caatccgtat cggtcaaggg gttgagtttg
    17281 actacgcaac cgttcactct gttaaggcta tccaggcagc tggttatgaa gctatcatca
    17341 tgaactcaaa cccagagacc gtttcaacag acttctctgt atcagataag ctttactttg
    17401 agccattgac attcgaagat gttatgaacg tcattgactt ggaacaacca aagggagtta
    17461 tcgttcagtt cggtggtcaa acagccatca accttgcgga gccattggca aaagcaggtg
    17521 tgaccatcct tggtacacag gttgctgacc tagatcgtgc cgaagaccgt gacctcttcg
    17581 agcaagctct caaagaattg gatattccac agccaccagg acaaacggct accaatgaag
    17641 aagaagcagc tcttgcagct cgcaagattg gcttcccagt tcttgtccgc ccatcttatg
    17701 tacttggtgg acgtgccatg gaaatcgttg aaaacgaaga agaccttcgt tcttacatgc
    17761 gaactgctgt taaggctagt ccagaccacc cagttcttgt cgactcttat atcgttgggc
    17821 aagagtgcga agttgatgcc atttcagatg gtaaaaatgt actcattcct ggtatcatgg
    17881 agcatatcga acgtgctggt gtccactcag gtgactcaat ggctgtttac ccaccacaaa
    17941 ccttgtcgca aaaggttcag gagaccatcg cagactacac caaacgctta gcaatcggtc
    18001 ttcactgcct tggaatgatg aacatccagt ttgttatcaa ggatgaaaaa gtctacgtta
    18061 ttgaggtcaa tccacgtgcc agccgtactg ttccattcct atctaaggta accaatattc
    18121 ctatggctca agtagcgacc aaactcattc ttggtcaaag tttatcagaa cttggctacc
    18181 aaaatggact ttaccctgaa agcacccgtg ttcatatcaa ggcacctgtc ttctccttta
    18241 ccaaactagc taaggtagac agcttgctcg gtcctgaaat gaagtcaaca ggtgaagtta
    18301 tgggttctga tgctactttg gaaaaagctc tctataaagc ctttgaagct tcttatctac
    18361 acttgccaac ttttggtaat gtcgtcttta ccatcgctga tgatgccaaa gaagaagcct
    18421 tgaacttggc tcgtcgtttc caaaacattg gttatggaat ccttgcgaca gaagggacag
    18481 cagccttctt tgctagtcat ggcttgcaag cccaacctgt tggtaagatt ggtgatgacg
    18541 ataaggatat cccaagtttt gtacgcaaag gaagaattca agctatcatt aacacagtag
    18601 gaacaaaacg aactgctgac gaagatggtg agcaaattcg tcgttcagcc attgaacacg
    18661 gggtgcccct cttcacagcg ctagatacag ctaatgccat gcttaaggta cttgaaagtc
    18721 gtagctttgt tacagaagcg atttaaatag aaaaataaga tatagcagac tgaatttaga
    18781 acagtacaca ggaatactaa aatatttcta
//
LOCUS       DAVLGK010000043        17119 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLGK010000043 DAVLGK010000000
VERSION     DAVLGK010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.043"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            86..826
                     /locus_tag="VXE01_001703"
     CDS             86..826
                     /locus_tag="VXE01_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0750567.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            823..1734
                     /gene="pfkB"
                     /locus_tag="VXE01_001704"
     CDS             823..1734
                     /gene="pfkB"
                     /locus_tag="VXE01_001704"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV0750568.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            1731..3683
                     /locus_tag="VXE01_001705"
     CDS             1731..3683
                     /locus_tag="VXE01_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0750569.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKTVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            3847..6072
                     /locus_tag="VXE01_001706"
     CDS             3847..6072
                     /locus_tag="VXE01_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV0750570.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPQLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(6117..6551)
                     /locus_tag="VXE01_001707"
     CDS             complement(6117..6551)
                     /locus_tag="VXE01_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750571.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
     gene            6714..8798
                     /locus_tag="VXE01_001708"
     CDS             6714..8798
                     /locus_tag="VXE01_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0750572.1"
                     /translation="MFEIRNLSLSFAGRRLLEPTDLIFERGKVYTIYGKSGVGKSSLL
                     NKIGLLSATDPSVSYFFDGKEIDIENKKSVSVFIAEEVAFVFQGRNLINDLTVFENLR
                     LALNFYDLSPDEIESKIDTVLADLQISSLKHAYPEDLSGGEEQRVAIARALVTGKTLI
                     LADEPTSSLDKENREKVSALLIDLAHKYHKIVLIVSHDEAMIAIGDVQLHFKDHKLVG
                     NCLILNSDEGIKDSKKWSSCLSSSHTKLSVLKHRRPFLPRLLAFFISLVVAIAVTSIN
                     FQSLFADKYHQLVNNSLENGFLVINDSLHLQTTKVLDDFLSFDKEEITSISTSQNIQT
                     VNPYIEFLSLGMTFDNSKDYSQLQKNFQPTLTIDGQTRSLTRNFSIQPLYQTNTTQRQ
                     IEYFDRSNEKGIYLSEQFISDEKLPNIVSGTTVTLTFYIPISLYESSIEKEGNILKGD
                     GDLFVKVDKTYPVLGIVKKSYPFEYSPYGNTLFMNIAEMEELQNEAIQQHPMTKMALD
                     GFPLKSWMPSAIHVLLKDSGAIPEELSRIRAISSQITILSSYENYEEFNKGLTYIRQF
                     LMLLSLVLLILVIAVLSFVFFLLNRPRRFEVGILKSLGYSTQNIVWLFLKELIGYGKI
                     ISILASCLLVILSILAMQVLKLEISDVFKFYLTSVFTLIGLSVSVLIISGLLPIYTTC
                     RQTVVDTIRKNG"
     gene            8808..9185
                     /locus_tag="VXE01_001709"
     CDS             8808..9185
                     /locus_tag="VXE01_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750573.1"
                     /translation="MKHKIMKKIIVVVFAIPWLTFLSQVHADYVSKSSSLDGYSLVGL
                     NVLNVTFNASGYSDTYSGSVSNMYFTDWAWFPNTISNRSTWKSSIPYGQRANGTVHIG
                     VGVNSPWGAVNLWGGQNYFSLDF"
     gene            9345..10487
                     /locus_tag="VXE01_001710"
     CDS             9345..10487
                     /locus_tag="VXE01_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0750574.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDFENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            10496..11710
                     /gene="thiI"
                     /locus_tag="VXE01_001711"
     CDS             10496..11710
                     /gene="thiI"
                     /locus_tag="VXE01_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV0750575.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            11845..12658
                     /locus_tag="VXE01_001712"
                     /pseudo
     CDS             11845..12658
                     /locus_tag="VXE01_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            12680..13015
                     /locus_tag="VXE01_001713"
     CDS             12680..13015
                     /locus_tag="VXE01_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEV0750576.1"
                     /translation="MHIEHLSHWSGHPNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGRVQFFTLSSVDSESWLATWKNAHDQAEMHRAYERYVIEEAILLS
                     STRQVSLMA"
     gene            13012..13419
                     /locus_tag="VXE01_001714"
     CDS             13012..13419
                     /locus_tag="VXE01_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0750577.1"
                     /translation="MMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYY
                     NDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDQK
                     QIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            13432..14598
                     /locus_tag="VXE01_001715"
     CDS             13432..14598
                     /locus_tag="VXE01_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0750578.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            15106..16599
                     /locus_tag="VXE01_001716"
     CDS             15106..16599
                     /locus_tag="VXE01_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0750579.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            16612..>17119
                     /locus_tag="VXE01_001717"
     CDS             16612..>17119
                     /locus_tag="VXE01_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0750580.1"
                     /translation="MKKVKLGEVCEILSGYAFKSSQFNDNKIGLPLIRIRDVERGFSD
                     TYFEGTYPEEYLIKNGDLLITMDGSFILKKWEGDLALLNQRVCKIKITDKSVDEGYIS
                     WLIPKFLKEIEDKTPFVTVKHLSVAKIKDISFVLPNKLEQKLIAKKLNTISQIYDFRK
                     IQSEKFNEL"
BASE COUNT         5196 a         3096 c         3744 g         5083 t
ORIGIN      
        1 tttgaaagaa aatgataaaa aatgcttgac ttcgaaagaa agtatgatag aatgaatagt
       61 gtaaacgata acaggaggtg attcagtgtt aaaaacagaa cgtaaacaac taattttaga
      121 ggagttaaat cagcatcatg tagtttctct agaaaaatta gttagtttgc tagaaacgtc
      181 agaatcaacg gttcgaagag acttggatga gttggaagcg gaaaacaagc ttcgtcgtgt
      241 gcatggtgga gcagaactcc cccactcctt acaggaagaa gaaaccattc aagaaaaatc
      301 tgtcaaaaac cttcaagaaa agaagttgct ggctcagaaa gcagcctctc tcattaaaga
      361 aaaagatgtc atctttatcg atgctggaac aacaactgct tttttgattc atgaattggt
      421 caataagaat gttacagttg tgaccaactc cattcaccat gccgctcagt tggttgaaaa
      481 gcagattcca actgtcatgg ttggaggaaa cgtcaagacg gcgacagatg ctagtatcgg
      541 gggcgttgct cttaaccaga ttaaccaatt gcactttgac cgtgccttta tcggaatgaa
      601 tggtgttgac gatggctatt atacgactcc tgatatggag gagggagctg tgaaaagagc
      661 tattttggag aatgccaagc agacctacgt cttggtggat tcgtcaaaaa ttggacaaac
      721 ttgctttgcc aaggtagcac cactcaaacg cgctatcgtt atcactagtc aagggcatga
      781 gctcttgcag gttattaagg agaaaacgga ggtaatagaa gtatgattta tacagtcaca
      841 ctcaatccat ccattgacta tatcgttcgt ttggaccaag tcaaagttgg tagtgtaaat
      901 cgtatggaca gtgatgataa gtttgctggt gggaaaggaa tcaatgtcag ccgtgtcttg
      961 aaacgtttga atataccaaa tacagcgacg ggatttatcg gtggctttac tggtaaattt
     1021 atcacagata ctttagcaga ggaagaaatc gagacacgtt ttgtccaggt ggcagaagat
     1081 actcgtatca atgttaaaat caaagcagac caagaaacag aaatcaacgg aacgggtcca
     1141 actgttgaat cggttcagct agaagaattg aaagctattt tatctagtct gacagcagaa
     1201 gatacagttg tctttgcagg ttcaagtgct aaaaatctag gcaatgttat ctataaggat
     1261 ttgatttcct tgacgcgcca gactggtgcg caagtggtct gtgactttga aggacagacc
     1321 ttaattgata gtttggacta ccagcctctt cttgtaaaac caaacaatca tgaacttgga
     1381 gcgatttttg gggttaaact cgaaagttta gatgaaattg agaaatacgc tcgtgagtta
     1441 ctggctaagg gtgctcaaaa tgttattatc tctatggctg gtgatggtgc ccttcttgtc
     1501 acatctgagg gagcttactt cgctaaacca atcaaaggaa cagtcaaaaa ttcagttgga
     1561 gctggtgatt ctatggttgc tggattcaca ggtgaatttg tcaaatcaaa agacgtagta
     1621 gaagccttca aatggggagt ggcttgcgga acggcaacta ccttctcaga tgacttggca
     1681 acggcggaat ttattaaaga aacatatgga aaagttgagg tagaaaaaag atgaaaattc
     1741 aagacctatt gagaaaagat gtcatgttgc tagatttgca ggcaactgaa aaaacagctg
     1801 tcatcgacga gatgattaaa aatttgacag agcacggtta tgtaacagat tttgaaacat
     1861 ttaaagaagg aattttggcg cgtgaagctt tgacttctac tggtttgggt gatggaatcg
     1921 caatgcctca cagcaaaaac gctgctgtca aagaagcgac agttctattt gctaagtcaa
     1981 ataagggtgt tgactacgag agcttggatg gacaagcaac tgacctcttc ttcatgattg
     2041 cagctccaga aggtgccaat gatactcact tggcagcctt ggcagaattg tctcaatact
     2101 tgatgaaaga cggttttgca gacaaacttc gtcaagcaac atctgcagac caagttatcg
     2161 aactttttga ccaagcttca gaaaaaactg aggaacttgt tcaagcacct gctaatgact
     2221 ctggtgactt tatcgtagct gttacagctt gtacaacagg tattgcccac acttacatgg
     2281 cccaagaagc ccttcaaaaa gtagctgctg aaatgggggt tggtatcaag gtcgaaacca
     2341 acggtgctag cggtgttgga aatcaactaa ctgcagaaga tatccgtaag gctaaagcta
     2401 ttatcattgc agcagacaag accgttgaaa tggatcgatt tgatggaaaa ccattgatca
     2461 atcgtccagt tgctgacggt atccgtaaga cagaagagct aattaacttg gctctttcag
     2521 gagatactga agtctaccgt gccgctaatg gtgccaaagc tgcaacagcc tctaacgaaa
     2581 aacaaagcct tggtggtgcc ttgtacaaac acttgatgag tggtgtatct caaatgttac
     2641 cattcgttat cggtggtggt atcatgattg cccttgcctt cttgattgac ggtgctttgg
     2701 gtgttccaaa tgaaaacctt ggcaatcttg gttcttacca tgagttagct tctatgttca
     2761 tgaaaattgg tggagctgcc tttggtttga tgcttccagt ctttgcgggt tatgttgcct
     2821 actctattgc tgaaaaaccg ggtttggtag caggtttcgt ggctggtgct attgccaaag
     2881 aaggttttgc ctttggtaaa attccttatg ccgcaggtgg tgaagcaact tcaactcttg
     2941 caggtgtctc atctggtttc ctaggtgccc ttgttggtgg atttatcgca ggtgccttgg
     3001 ttcttgccat caagaaatac gttaaagttc ctcgttcact cgaaggtgct aaatcaatcc
     3061 ttctattgcc acttcttgga acaatcttga caggatttgt tatgctagct gtgaatatcc
     3121 caatggctgc aatcaacact gctatgaatg acttcctagg cggtcttgga ggaggttcag
     3181 ctgtccttct tggtatcgtc cttggtggaa tgatggctgt tgacatgggt ggaccagtta
     3241 ataaagcagc ttatgtcttt ggtacaggta cgcttgcagc aactgtttct tcaggtggtt
     3301 ctgtagccat ggcagcagtt atggctggag gaatggtgcc accacttgca atctttgtcg
     3361 caactcttct tttcaaagat aaatttacta aggaagaacg taactctggt ttgacaaaca
     3421 tcatcatggg cttgtcattt atcactgagg gagcgattcc atttggtgcc gctgacccag
     3481 ctcgtgcgat tccaagcttc atccttggtt cagcagtagc aggtggactc gttggtctta
     3541 ctggtatcaa actcatggcg ccacacggag gaatcttcgt tatcgccctt acttcaaatg
     3601 ctctccttta cctcgtttct gtcttggtag gagcaatcgt aagtggtgtg gtttatggtt
     3661 acctacgcaa accacaagca taaaaaatag aaaaatgaaa agattggacc gtttggtgca
     3721 gtctttttct cttcccgaaa tgcctgtgaa atatggtata atagaagaat ggcaaacaag
     3781 aatacaagta caacaagacg gagaccgtct aaagcagaac tggaaagaaa agaagcgatt
     3841 caacgaatgt tgatttcatt aggaattgcg attttattga ttttcgcagc cttcaaatta
     3901 ggggctgcag gtataaccct ttataattta attcgcttgc tagtgggtag cctagcttat
     3961 ctggcgatat tcggcctatt aatctatctc ttctttttca agtggatacg aaaacaggaa
     4021 ggactcttat ctggcttttt caccatattt gctggcttac tcttgatttt tgaagcctac
     4081 ttggtttgga aatatggttt ggacaagtcc gttctaaaag ggaccatggc tcaggttgtg
     4141 acagatctga ctggttttcg aacgactagc tttgctggag ggggcttgat aggggtcgct
     4201 ctttatattc caacagcctt tctcttttca aatatcggaa cttactttat tggttctatc
     4261 ttgattttag tgggttctct cctagtcagc ccttggtctg tttacgatat tgctgaattt
     4321 ttcagtagag gctttgccaa atggtgggaa gggcacgagc gtcgaaaaga ggaacgcttt
     4381 gtcaaacaag aagaaaaagc tcgccaaaag gctgagaaag aggctagatt agaacaagaa
     4441 gagactgaaa aagccttact cgatttgcct cctgttgata tggaaacggg tgaaattctg
     4501 acagaggaag ctgttcaaaa tcttccacct attccagaag aaaagtgggt ggaaccagaa
     4561 atcatcctgc ctcaagctga acttaaattc cctgaacagg aagatgactc agatgaccaa
     4621 gatgttcagg tcgatttttc agccaaagaa gcccttgaat acaaacttcc aagcttacaa
     4681 ctctttgcac cagataaacc aaaagatcag tctaaagaga agaaaattgt cagagaaaat
     4741 atcaaaatct tagaagcaac ctttgctagc tttggtatta aggtaacagt tgaacgggcc
     4801 gaaattgggc catcagtgac caagtatgaa gtcaagccgg ctgttggtgt aagggtcaac
     4861 cgcatttcca atctatcaga tgacctcgct ctagccttgg ctgccaaaga tgtccggatt
     4921 gaagcaccaa tccctgggaa atccctaatc ggaattgaag tgcccaactc cgatattgcc
     4981 actgtatctt tccgagaact atgggaacaa tcgcaaacga aagcagaaaa tttcttggaa
     5041 attcctttag ggaaggctgt taatggaacc gcaagagctt ttgacctttc taaaatgccc
     5101 cacttgctag ttgcaggttc aacgggttca gggaagtcag tagcagttaa cggcattatt
     5161 gctagcattc tcatgaaggc gagaccagat caagttaaat ttatgatggt cgatcccaag
     5221 atggttgagt tatctgttta caatgatatt ccccaactct tgattccagt cgtgaccaat
     5281 ccacgtaaag ccagcaaggc tctgcaaaag gttgtggatg aaatggaaaa ccgttatgaa
     5341 ctctttgcca aggtgggagt tcggaatatt gcaggtttta atgccaaggt agaagagttc
     5401 aattcccagt ctgagtacaa gcaaattccg ctaccattca ttgtcgtgat tgtggatgag
     5461 ttggctgacc tcatgatggt ggccagcaag gaagtggaag atgctatcat ccgtcttggg
     5521 cagaaggcgc gtgctgcagg tatccacatg attcttgcaa ctcagcgtcc atctgttgat
     5581 gtcatctctg gtttgattaa ggccaatgtt ccatctcgtg tagcatttgc ggtttcatca
     5641 ggaacagact cccgtacgat tttggatgaa aatggagcag aaaaacttct tggtcgagga
     5701 gacatgctct ttaaaccgat tgatgaaaat catccagttc gtctccaagg ctcctttatc
     5761 tcggatgacg atgttgagcg cattgtgaac ttcatcaagg ctcaggcaga tgcagactac
     5821 gatgagagtt ttgatccagg tgaggtttct gaaaatgaag gagaattttc ggatggagat
     5881 gctggtggtg atccgctttt tgaagaagct aagtctttgg ttatcgaaac acagaaagcc
     5941 agtgcatcca tgattcagcg tcgtttgtca gttggattta accgtgcgac ccgtctcatg
     6001 gaagagcttg agatggcagg tgtcattggt ccagctgaag gtaccaaacc aagaaaagtt
     6061 ttacaacaat aaaaaaatag cttctttcca agtttggaag gaggctattt tagtgattat
     6121 tgattagttt tattttccga agttggggta ttggactgtt tttcgttttc agtagcaggt
     6181 ttacttggag taggagcagg agtagaagaa tcctgagttg atgttttctg ctcttctttt
     6241 ttctcttcct tgacgctgga ttttggcgtt tcttcttgtt gtgttttttc ttgagaagtc
     6301 ttattttcct tattgggact agtattttcc tgaggggatt ccttttgaat ttctttgaca
     6361 attgttgtcg tctggcttgt tgtaggttcc tttttagtat ttttgttatt atccaaggcg
     6421 ttcataatcg tgatactagc ggtaatcaag ccaaggatac tagcgatagt cgcaacggtt
     6481 ttttgaaaga ctgtaaagcc ttttttgatg tgttctgttt ttggttttga agttctacga
     6541 taattagaca tacattctct cctttaatta aaatttatta tacctcattt ctttaaaaaa
     6601 atcttaaaaa aagaggagat ttttctacac gaacttcagt aattagttga aataaaatat
     6661 gacttatgat ataacaaaat aaagaaagcg atttcaaaaa aggagggcgt tatatgttcg
     6721 aaattagaaa tttgagtctc tcttttgcag gcaggcggtt gctagagcca acagatttga
     6781 tatttgaaag gggaaaagta tatacaatat atgggaagtc aggcgtagga aagtcttctt
     6841 tactgaataa aattggtttg ctctctgcta cggatcctag tgtttcttat ttcttcgatg
     6901 gaaaagagat tgatatcgaa aataagaaat cagtctctgt ctttatagct gaagaagttg
     6961 cctttgtatt tcaggggcga aatctaataa atgatttgac cgtatttgaa aatttaagac
     7021 tagctttaaa cttttatgac ttgagtccag atgaaataga aagcaaaatt gatacagtat
     7081 tggcggattt acagatttct tctttaaagc atgcttatcc agaagattta tccggtggtg
     7141 aagaacaacg agtggcaatc gcaagagcct tagttacagg aaagactctc atcttagctg
     7201 atgaaccaac aagttctttg gataaagaaa atagagaaaa agtctccgcc ttgttaattg
     7261 atttagctca caaatatcat aaaattgtat tgattgtttc gcatgatgag gcgatgattg
     7321 caataggaga tgttcagctt cattttaaag accataaatt agttgggaat tgtcttattt
     7381 tgaattctga tgaagggata aaggattcta agaagtggtc ctcctgtttg tcgtcttctc
     7441 atacgaagct atccgttttg aaacatagaa ggcctttttt acctagatta ttagcgtttt
     7501 ttatctctct tgtagttgct atagcagtaa cctctattaa ctttcagtcc ttatttgcag
     7561 ataagtatca ccaactggtg aacaactcac tcgaaaatgg cttcttggtg attaatgatt
     7621 cgcttcattt acaaactaca aaagtgttgg atgattttct cagttttgat aaagaggaaa
     7681 tcacctcaat tagcacaagt cagaatattc aaaccgtcaa tccttatata gagtttctct
     7741 ctttgggtat gacgtttgat aattcaaaag actattcaca acttcaaaag aactttcagc
     7801 caactttgac tattgatggt cagaccagaa gcttgacaag aaatttttca attcaaccct
     7861 tgtatcagac aaatacaaca cagaggcaga tagagtattt tgataggagc aatgaaaaag
     7921 ggatttatct atctgagcaa ttcatttcag atgaaaaatt accaaatata gtttcgggaa
     7981 ctaccgtgac actgactttt tatattccaa tttctttata tgaatcaagt atagagaaag
     8041 aggggaatat attgaaagga gatggcgatt tatttgtcaa agtggataaa acatatcctg
     8101 ttttagggat tgttaaaaaa agttatccgt ttgaatattc cccttatggg aacaccctat
     8161 ttatgaatat tgctgaaatg gaagaattgc aaaatgaagc aattcaacag catcccatga
     8221 cgaagatggc tttagatggt tttcctttga aatcatggat gccgagtgcg attcatgtgt
     8281 tactaaagga tagcggtgct attcctgaag aattgagtag aataagagca atctcttcac
     8341 aaattactat tttatcatca tatgaaaact acgaagaatt taataaagga ctcacctata
     8401 tcaggcaatt tttaatgttg ctatccctag tcttactcat ccttgtcatc gcagtattgt
     8461 cctttgtttt ctttttgctc aatcgtcctc gacgctttga agtagggatt ttaaaatctt
     8521 tgggatacag tactcaaaat attgtttggc ttttcttaaa agaattaatt ggttatggta
     8581 aaataatttc gatattagca agttgtttac tcgtcattct ttccatttta gcaatgcaag
     8641 tgcttaaatt ggaaatttca gatgttttta aattctatct aacttccgtt ttcaccttaa
     8701 ttggattatc agtctcagta ctgataataa gtggcttact acctatatac acaacttgta
     8761 ggcaaacagt tgtcgatact atccgaaaga atggatgagg tgatatcatg aaacataaga
     8821 taatgaaaaa aataatagtg gtagtgtttg ctatcccatg gttaacattt ttaagtcaag
     8881 tacatgcaga ttatgtaagt aagtctagtt ctttagacgg ttatagcttg gtaggcttga
     8941 atgttcttaa tgtgactttt aatgcttctg gctattctga tacttatagt ggcagtgtgt
     9001 caaatatgta tttcactgac tgggcttggt ttcctaatac gataagtaat cgttccactt
     9061 ggaaaagttc gattccatat ggtcaacgcg caaatggtac agtccatata ggtgtaggag
     9121 taaattcgcc ttggggagcg gttaatctct ggggcggaca aaattacttt tctttagatt
     9181 tttaacagaa ataatcaaag ttagatagaa tgaataagaa tgctcttgat gatggtatca
     9241 agagtatttt atgttattca gattaatgca aacattgccc tttcttgtcg caggctccgt
     9301 ttcatgatac aatagaagga gtgattttag aaagcgtgag aaacatgatt tactttgata
     9361 attcggcgac gaccaggccc tatccagaag cccttgaaac ctatatgcag gtggcttcaa
     9421 aaattttagg aaatccatct agtctccatc gtttgggaga ccaggcaaca cgaattttag
     9481 atgcttcccg tcaacagatt gcagatttaa tcggtaagaa aagtgatgaa atcttcttta
     9541 catctggtgg gacagaaggg gataactgga tcatcaaggg agtagcattt gaaaaagccc
     9601 agtttggcaa gcacatcatc gtatcagcca ttgaacatcc agcagttaag gaatcagccc
     9661 tctggttgaa agctcaaggt tttgaagtgg attttgctcc agttgataac aaaggatttg
     9721 tggatgttga ggcgctagaa gatttgataa gacctgatac gaccctcgtt tccatcatgg
     9781 cagttaacaa tgaaattggc tctgttcagc ccattgaggc tatttcaaaa ctattggcag
     9841 acaagccaac tatttccttc cacgttgatg cggttcaggc gcttgccaag attccgactg
     9901 aaaagtatct gacagaacga gtggatttcg cgactttctc tggtcacaag ttccacggaa
     9961 tccgtggtgt tggttttatc tatatcaagt ctggcaagaa gattacgcct cttttaacag
    10021 gtggtggtca ggaacgtgat taccgttcga caactgaaaa tgtggcagga attgcagcga
    10081 ccgctaaggc tctccgttta tctatggaaa agctagatat ctttaggagc aagactgggc
    10141 agatgaaggc agtgattcgt caagcacttc tggactatcc ggatatattt gtcttttcag
    10201 atgaggaaga cttcgcccct catattctga cttttggaat caagggtgtt cgtggtgagg
    10261 tcattgttca cgcctttgaa gactatgata ttttcatctc aacgacctcg gcttgttcgt
    10321 ccaaggctgg gaaaccagcc ggaaccctga ttgctatggg agtggacaag gataaggctc
    10381 agtcagctgt gcgtcttagt ctagactttg aaaatgatat gagtcaggtc gagcagttct
    10441 tgaccaagct aaaattaatt tacaatcaaa ctagaaaagt aagataggag cattcatgca
    10501 gtattcagaa attatgattc gctacggtga gctgtcaacc aagggcaaaa atcgtatgcg
    10561 tttcatcaat aaacttcgca ataatatttc agacgttttg tctatctatc cccaagttaa
    10621 ggtaacagca gatcgcgacc gtgcccacgc ttacctcaat ggagcagatt acacagcagt
    10681 agcagaatcg ctcaaacaag tatttggaat tcaaaacttt tcccctgttt ataaggttga
    10741 aaaatctgta gaagttctga agtctgctgt ccaagagatt atgcaggaca tctacaagga
    10801 aggcatgacc tttaaaatct ctagcaagcg tagcgaccac acctttgaat tggacagtcg
    10861 tgaactcaac caaacgcttg gaggggctgt attcgaagcc attccaaacg tacaagctca
    10921 aatgaaaagt cctgacatca atcttcaggt ggagatacgt gaagaagcag cctatctttc
    10981 ttatgaaacc gttcgagggg caggtggatt accagtggga acttctggta agggcatgct
    11041 catgttgtca gggggaatcg attcccctgt agctggctat ctagcgctta aacgaggggt
    11101 agatatagag gcagttcact ttgccagccc accttacacg agtcctggtg ctcttaaaaa
    11161 agcccaagat ttgacccgta aattaaccaa atttggggga aatatccagt ttatcgaagt
    11221 tccttttaca gagattcaag aggaaatcaa agccaaagcg ccagaagcct accttatgac
    11281 cttgacgcgt cgttttatga tgcgtattac tgaccgtatt cgtgaggtac gaaatggttt
    11341 agttatcatc aatggggaaa gtctaggtca agtagccagc caaacccttg aaagtatgaa
    11401 ggctatcaat gctgttacca acactcccat cattcgtcct gtggttacca tggacaagtt
    11461 ggaaatcatt gacatcgccc aggaaatcga tacctttgac atttcaatcc aaccgtttga
    11521 agactgttgt accatttttg caccagatcg tccaaaaaca aatcctaaaa ttaagaatgc
    11581 ggagcagtac gaagcgcgta tggatgttga aggcttggtt gagcgagcag tggctggaat
    11641 catgattact gaaatcacac ctcaagccga aaaagatgaa gttgatgact tgattgacaa
    11701 tctgctctaa ttcagaaaat ccaaaagaat agcgaaaatc agtaaaaaaa gttagttttt
    11761 tctctaaaaa caggtaaaaa actaactttt tttattttta tgatataatg atataaaatt
    11821 ttgaatatag agagttttct gacaatgaat caatcctact tttatctaaa aatgaaagaa
    11881 cacaaactca aggttcctta tacaggtaag gagcgccgtg tacgtattct tcttcctaaa
    11941 gattatgaga aagatacaga ccgttcctat cctgttgtat actttcatga cgggcaaaat
    12001 gtttttaata gcaaagagtc tttcattgga cattcatgga agattatccc agctatcaaa
    12061 cgaaatccgg atatcagtcg catgattgtc gttgctattg acaatgatgg tatggggcgg
    12121 atgaatgagt atgcggcttg gaagttccaa gaatctccta tcccagggca gcagtttggt
    12181 ggtaagggtg tggagtatgc tgagtttgtc atggaggtgg tcaagcattt tatcgatgag
    12241 acctatcgta caaaagcaga ctgccagcat acggctatga ttggttcctc actaggaggc
    12301 aatattaccc agtttatcgg tttggaatac caagacaaaa ttggttgctt gggcgttttt
    12361 tcatctgcaa actggctcca ccaaccgcta tatcgagtgc cagaaactat cgcctgacca
    12421 acgcatcttc atctatgtag gaacagaaga agcagatgat acagacaaga ccttgatgga
    12481 tggcaatatc aaacaagcct atatcgactc gtcgctttgc tattaccatg atttgatagc
    12541 agggggagta catctggata atcttgtgct aaaagttcag tctggtgcca tccatagtga
    12601 aatcccttgg tcagaaaatc taccagattg tctgagattt tttgcagaaa aatggtaagt
    12661 taagaaagga aaaaacgaaa tgcatattga acatcttagc cactggagtg gtcatcctaa
    12721 ccgtgaaatg taccttaacc gttatggaca tggtgggatt ccagttgtgg tctttgcttc
    12781 atcaggtggt agtcacaacg aatactatga ttttggcatg attgatgcct gtgcttcctt
    12841 tatcgaggaa ggccgtgtcc agttctttac cctatctagt gtggatagtg agagctggtt
    12901 ggctacttgg aaaaatgctc atgaccaagc ggaaatgcac cgtgcctacg aacgttatgt
    12961 gattgaggag gccattcttt tatcaagcac aagacaggtt agtttgatgg catgatgacg
    13021 acaggttgct ctatgggagc ctatcatgca ctcaatttct tcctccagca tccagatgtc
    13081 tttaccaaag tgattgctct cagtggtgtt tacgacgcac gtttctttgt cggtgattac
    13141 tacaacgatg atgctattta ccaaaactcg ccagtagatt atatttggaa ccaaaacgat
    13201 ggctggttta ttgaccgtta ccgtcaggca gagattgtgc tgtgtacggg gcttggagcc
    13261 tgggaacaag atggtttacc atccttttac aagctcaaag aagcctttga ccagaaacaa
    13321 attccagcct ggtttgctga atggggacat gatgtcgccc acgactggga atggtggcgt
    13381 aaacaaatgc cttatttcct cggtaatctc tatttataaa aggagttacc tatgaattac
    13441 cttgttattt ctccctacta tccacaaaac tttcaacagt ttaccatcga actagctaat
    13501 aaaggcatca cagtcttggg aattggtcaa gagtcttacg agcaattgga tgagcccttg
    13561 cgcaatagct tgaccgagta ttttcgtgtt gataatcttg agaacataga tgaagtcaaa
    13621 cgtgcagttg cttttctctt ttataaacat ggtccaattg accgcatcga gtctcacaat
    13681 gaatactggc ttgagctaga cgcaacactc agagaacaat tcaatgtttt tggtgccaaa
    13741 ccagaggatc tcaaaaagac gaaatataag tctgaaatga agaaactttt caaaaaagca
    13801 ggtgttcctg tggtacctgg agctgttatc aagacggaag cagatgttga tcaagcagtg
    13861 aaagaaatcg gtcttccaat gattgccaaa cctgataatg gagtgggagc agccgcaacc
    13921 tttaaacttg agacagaaga cgatatcaat cacttcaagc aagaatggga ccattcaacc
    13981 ctttatttct ttgaaaaatt tgtcacttcc agcgaaatct gtacctttga cgggctcgtg
    14041 gacaaggatg gaaagattgt cttctcaaca acctttgact acgcctatac accgcttgac
    14101 ctcatgattt ataagatgga caattcttat tatgtgctca aggatatgga tcctaaactg
    14161 cgcaagtatg gggaagcaat tgtcaaagaa tttggtatga aagaacggtt tttccatatt
    14221 gagttcttcc gtgaggggga cgattatatt accatcgagt acaataaccg ccctgcaggt
    14281 ggttttacca ttgatgttta taactttgct cattccttgg acctttatcg tggctatgca
    14341 gctattgtcg caggagagga gttcccggcg tcagactttg aaactcagta ttgtttggct
    14401 acttctcgcc gtgcaaatgc tcactatgtt tattcagaag aggatttgct tgccaaatat
    14461 agccagcagt tcaaggttaa aaaagtcatg ccagctgcct tcgcggaact tcaaggagat
    14521 tacctgtata tgctgacaac tccgagtcga caagaaatgg atcagatgat tgctgatttc
    14581 ggacaacgtc aagaataaga actatcggat taaggaaatt cactccctta atccttttgt
    14641 tttgtctggt aaaaaataag agcatcctaa caaggtagct atcataaaac ttgttcgata
    14701 actatttgaa gcaggattag gtggctagaa attgaatttt aacatttcaa tttagtcata
    14761 gtattgtgtt ttcgtatcct taaatcagct aaaaggatcc atgacgacac ctatacgata
    14821 tagttttcag gataccaaac cagtctatta atactcaatg aaaatcaaag agcaaactag
    14881 gaagctagcc gcaggttgct caaaacactg ttttgaggtt gtggatagaa ctgacagagt
    14941 cagtatcata tacctacggc aaggtgaagc tgacgtggtt tgaagagatt ttcgaagagt
    15001 ataaaatatt caggtgacgc atagatatag ttaattgaag ctttgtttga aatctgataa
    15061 aataatgata ttactaagtt ttaaaaacta aagaaaaggg aagatatgat tacaggcgaa
    15121 ttaaaaaata aaatcgatca gctgtgggaa attctttgga cagaaggaaa cgcaaatcct
    15181 ttaacaaata ttgaacagtt gacttatctc ttatttatga aagatttgga tagtgtcgag
    15241 cttggacgtg aaagtgatgc tgaatttcta gggattcctt atgagggagt ttttccaaaa
    15301 gataaacctg aataccgttg gtcaactttt aaaaatatag gagatgctca ggaagtttat
    15361 cgtttaatga ctcaggagat ttttccgttt attaaaaatc tcaaggggga tacagatgat
    15421 acagcctttt cacgatatat gcgagaagct atttttcaaa taaataaacc tgctacgctt
    15481 caaaaggcaa tttctatctt agatgttttt ccaactaggg gattagatgt agattttgat
    15541 aatgacaaac aaagtattac tgatatcgga gatatctatg aatatctgtt atcaaaattg
    15601 tcgaccgcag gtaaaaatgg acagttccgt acacctcgtc acatcatcga tatgatggtt
    15661 gagttgatgc aaccgactat caaagatatc atctcagatc ccgctatggg ttctgctggc
    15721 ttcttagtat ctgctagccg ttacttaaag cgtaagaaag atgaatggga aaccaataca
    15781 gataatatca atcattttca taatcagatg tttcatggaa atgatacgga tacgactatg
    15841 ttgagacttg gggcgatgaa catgatgcta catggagtag aaaatccaca aatcagttac
    15901 cttgactcgc tgtctcaaga taatgaagaa gccgataaat atactttggt tttagcaaat
    15961 cctcctttta agggctcact tgactacaat tcaacctcta atgaccttct tgcaaccgta
    16021 aaaaccaaaa aaacagaatt actctttctt tctcttttct tgcgaacttt aaaaccaggt
    16081 ggacgagcag cagttatcgt acctgatggt gtcctttttg gttcgtctaa agctcataaa
    16141 ggaattcgtc aggaaattgt agagaatcat aagcttgatg ctgtaatctc aatgcctagt
    16201 ggtgtgttca agccttatgc tggagtttca actgccattc tcatctttac aaaaactggt
    16261 aatggtggta ctgacaaagt ctggttttac gatatgaaag cggatggttt aagtttggat
    16321 gataagcgac aaccgattag cgacaatgat attccagata ttatcgaacg ctttcatcat
    16381 cttgaaaaag aagcagaacg tcagagaacg gatcaatctt tctttgttcc agttgctgag
    16441 ataaaggaaa atgattatga tttgtctatc aataaatata aagagattga gtatgaaaaa
    16501 gttgagtatg aaccaacaga agtcatatta aagaaaatca atgatttaga aaaagaaatt
    16561 caagctggct tggctgaatt ggaaaaatta ctcaagtagg gaggtggctg tatgaaaaaa
    16621 gtgaagttgg gggaagtttg tgagatttta tctggttacg cttttaaatc atcacaattt
    16681 aatgataaca aaattggtct ccccttaata cgaattcgag atgtagaaag aggtttttct
    16741 gatacctact ttgaaggaac ttatcccgaa gaatatctta ttaaaaatgg agacttattg
    16801 attacaatgg atggcagttt tatattgaaa aaatgggagg gggatttagc gctacttaat
    16861 caacgtgtct gtaaaattaa aattacggat aaaagtgtag atgaaggtta tatatcttgg
    16921 ttgattccta aatttttaaa agaaattgaa gataagaccc cttttgttac agtgaaacat
    16981 ctttcagtag ctaaaataaa agatatctca tttgtattgc ctaataaact agaacaaaag
    17041 ctaattgcaa aaaaactaaa tacgataagt caaatttatg attttcgtaa aattcaatca
    17101 gaaaaattta acgagctcg
//
LOCUS       DAVLGK010000044        15122 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLGK010000044 DAVLGK010000000
VERSION     DAVLGK010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15122
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.044"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            12..488
                     /locus_tag="VXE01_001718"
     CDS             12..488
                     /locus_tag="VXE01_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0750581.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            526..828
                     /locus_tag="VXE01_001719"
     CDS             526..828
                     /locus_tag="VXE01_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0750582.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            836..1640
                     /locus_tag="VXE01_001720"
     CDS             join(836..1204,1206..1640)
                     /locus_tag="VXE01_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0750583.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDFLMATLQYVREYRTYEEIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKELANYSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQIPRKSSKLKPLIAEDKAYNHA
                     LSKDRSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            1689..2153
                     /locus_tag="VXE01_001721"
     CDS             1689..2153
                     /locus_tag="VXE01_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV0750584.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2311..2736
                     /gene="lacA"
                     /locus_tag="VXE01_001722"
     CDS             2311..2736
                     /gene="lacA"
                     /locus_tag="VXE01_001722"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV0750585.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2767..3282
                     /gene="lacB"
                     /locus_tag="VXE01_001723"
     CDS             2767..3282
                     /gene="lacB"
                     /locus_tag="VXE01_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV0750586.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3293..4222
                     /locus_tag="VXE01_001724"
     CDS             3293..4222
                     /locus_tag="VXE01_001724"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV0750587.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYCASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFTKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            4224..5204
                     /gene="lacD"
                     /locus_tag="VXE01_001725"
     CDS             4224..5204
                     /gene="lacD"
                     /locus_tag="VXE01_001725"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV0750588.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5438..6274
                     /locus_tag="VXE01_001726"
     CDS             5438..6274
                     /locus_tag="VXE01_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0750589.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6310..6627
                     /locus_tag="VXE01_001727"
     CDS             6310..6627
                     /locus_tag="VXE01_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0750590.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6627..8318
                     /locus_tag="VXE01_001728"
     CDS             6627..8318
                     /locus_tag="VXE01_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0750591.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDVAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            8533..9939
                     /gene="lacG"
                     /locus_tag="VXE01_001729"
     CDS             8533..9939
                     /gene="lacG"
                     /locus_tag="VXE01_001729"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0750592.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNVKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9982..10191
                     /locus_tag="VXE01_001730"
     CDS             9982..10191
                     /locus_tag="VXE01_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV0750593.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEE"
     gene            complement(10518..11279)
                     /locus_tag="VXE01_001731"
     CDS             complement(10518..11279)
                     /locus_tag="VXE01_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0750594.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(11461..12423)
                     /gene="nrdF"
                     /locus_tag="VXE01_001732"
     CDS             complement(11461..12423)
                     /gene="nrdF"
                     /locus_tag="VXE01_001732"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV0750595.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSADD
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEVMQDDDYNYGLD"
     gene            complement(12611..14770)
                     /gene="nrdE"
                     /locus_tag="VXE01_001733"
     CDS             complement(12611..14770)
                     /gene="nrdE"
                     /locus_tag="VXE01_001733"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV0750596.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(14851..15069)
                     /gene="nrdH"
                     /locus_tag="VXE01_001734"
     CDS             complement(14851..15069)
                     /gene="nrdH"
                     /locus_tag="VXE01_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV0750597.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
BASE COUNT         4690 a         2723 c         3098 g         4611 t
ORIGIN      
        1 gggaaaacct tatggtatta gattatttct ttgacaaaaa ccttgtgttt tgcttagaag
       61 cggataatca agaacaactc tttgatcagg tagcaagctt gttggaagaa cgagaaattg
      121 tcactccaac ttatcgtgaa gccttgatca cgcgtgaaaa gtcatttcca actggtttag
      181 atatggaatt tctaggaaag gacttgccaa atgtagcgat tcctcacaca gatattgttc
      241 ataatctagc tgaaaaagtg gtggttgttc gattagaaaa accagtaact tttcacaata
      301 tgattgcgcc aggtaaggaa gtagaagtat ccctactctt ctttatcatt aacaattcaa
      361 gttcaagtca aacaaatatt ctggctcagt tgatggactt tttcacagga aatggacatc
      421 ttgaagacct atcaaaaatt tccgaaccag aaaaacttta tgcttacatt gctgaagcaa
      481 ccgcttaatc ttgtctatta aaaaataaaa tcggaggaaa tctaaatgat taaaattctt
      541 gctgcctgcg gtgcaggtgt taactcaagt caccaaatta aaagtgctct agaagaagaa
      601 ctttcaaacc gtggttatga tgttcactgt gatgcagtta tggtgaaaga tgtaaacgaa
      661 gaccttatga aaggttacga tatctttaca ccaatcgctg caacagacct tggttttgaa
      721 ccaggtatcc cagttatcga agctgggcca atcttattct gtatcccagc aatgagcgtt
      781 ccagtatttg acaatattag acttcctgcg aaacaaaata tggtatagta gttccatgaa
      841 ttatgaagca agtaaacaac taactgatgc acgatttaag cgtcttgttg gtgttcaacg
      901 cacgactttt gaagagatat tagctgtatt aaaaacagct tatcaactta aacacgcaaa
      961 aggtggacga aaacctaaat taagcctaga agactttctt atggccactc ttcaatatgt
     1021 gcgagaatat cgaacttatg aagaaattgc ggctgatttt ggtatccacg aaagcaactt
     1081 aatccgtcgg agccaatggg ttgaagtaac tcttgttcaa agtggtgtta cgatttcaag
     1141 aactcctctc agttctgagg acacggtaat gattgatgcg acggaagtac aaatcaatcg
     1201 ccctaaaaaa agaattagcg aattattctg gtaaaaagaa atttcacgct atgaaggctc
     1261 aagcgattgt cacaagtcaa gggagaattg tttctttgga tatcgctgtg aactattgtc
     1321 atgatatgaa gttgttcaaa atgagtcgca gaaatatcgg acaagctggt aaaatcttgg
     1381 ctgacagtgg ttatcaaggg ctcatgaaga tatatcctca agcacaaatt ccacgtaaat
     1441 ccagcaaact caagccgcta atagctgaag ataaagccta taaccatgcg ctatctaagg
     1501 atagaagcaa ggttgagaac atctttgcca aagtaaaaac gtttaaaatg ttttcaacaa
     1561 cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgagtgct ggtattatca
     1621 atcatgaact aggattctag ttttgcagga agtctaataa agaaactagc aaggtcaggc
     1681 cttactttat tggtggacat ccaggattta attgtcttct acttgatgat gaagtctatg
     1741 aagattatta tctagagttt gagaaagaag agatttgctc tgttccacgt cctttcccag
     1801 aaacaggtat gttggatttc caagatagaa gtccatggct agagggacaa aaagaaatag
     1861 atcttagtta tgatcttttc agcacagatg cagtgacttt ggatgaattg caatctcgaa
     1921 caattgccct tcgttctctt aaacatgata agggattgaa agtgcatttt gcagaatttc
     1981 caaacctcat catctggtca actttgaaca agggaccttt cattaccttt gaaccatggt
     2041 ctggcttgtc aacattcctt gaagaaggag atcatttaga agataagaag aatgtttgtc
     2101 tcttagaagc caatcaggtt gaagaattag ggtttgagat agaagtttta taaaaaaagt
     2161 aaaaaataaa taacaaaaac aaacacaaac tgttgacttc ttcaaacaat agtagtatat
     2221 tatgtttgtg aggactaatt gactgttttt taaagacagc caatacactg ctggaatcca
     2281 gcatagaaaa aataaaaagg agtatacaat atgtctattg ttatcggtgc agatgctgca
     2341 ggtttgagat tgaaagaagt tgtgaaagac ttcttagaaa aagaaaactt ccaccttgtg
     2401 gatgttacag ctgaaggtca agactttgtt gatgtgactc tcgctgttgc tgcagaagta
     2461 aacaaagaag aacaaaacct tggtatcgtg attgatgctt atggagctgg tccatttatg
     2521 gttgcaacta agatcaaagg aatggttgct gcagaagtat ctgacgaacg ttcagcttat
     2581 atgactcgtg gccacaacaa ctcacgtatg atcactatgg gggcacaact tgttggtgat
     2641 gaattggcta aaaacatcgc taaaggattt gttaatggta aatacgacgg tggtcgtcac
     2701 caaatccggg ttgacatgtt gaacaaaatg tgctaattag attatagtaa gaaaggtaag
     2761 ttaaaaatga gaattgcaat tggatgtgac cacatcgtaa cagatgaaaa aatggcggtt
     2821 tcagaatttt tgaaatcaaa aggatatgaa gtcattgact ttggtaccta tgaccataca
     2881 cgtactcact acccaatctt tggtaaaaaa gtaggggaag cagtaactag tggtcaagct
     2941 gatctcgggg tatgtatctg tggtactggt gttggtatca acaacgctgt aaataaagtt
     3001 ccaggtgttc gttctgcctt ggttcgtgat atgacaacag ccctttatgc taaagaacaa
     3061 ttgaacgcca acgttatcgg ttttggtggt aagattactg gtgaattgct tatgtgtgat
     3121 atcatcgaag ctttcattca tgctgaatac aaaccatctg aagaaaacaa aaaattgatt
     3181 gcgaaaattg aacaccttga aagtcacaat gctcaacaaa cagacgcaaa cttcttcact
     3241 gaattccttg aaaaatggga tcgtggagaa taccacgact aagaggtaac ctatgatttt
     3301 aacagttaca atgaacccat ccattgatat ttcctatccc ttggatgagt tgaagattga
     3361 tactgtcaat cgtgtggtgg atgtaaccaa aacggctggt ggtaagggac tcaatgttac
     3421 ccgagtactt tcagaatttg gcgattctgt tcttgctact ggtttagtgg gtggcaaact
     3481 tggtgagttt ttggttgaac atatcgataa tcaagtaaag aaagatttct tctcaattca
     3541 gggagaaact cgtaactgta tcgctattct ccacggagac aaccaaacag aagttcttga
     3601 aaaaggtcct gaagtattgg aacaggaagg tcaagacttt ttggaacatt tcaaaaaact
     3661 cttggagtca gttgaagtag tggccatctc aggtagtctg ccagctggcc ttccagttga
     3721 ttactgtgcg agcttggtag aacttgctaa tcaagctggc aagcctgtag tcttggactg
     3781 ctcaggtgca gcacttcagg ctgttcttga atcaccccat aaaccaacag tcatcaaacc
     3841 aaataatgaa gaattgtctc agcttcttgg aagagaagtt tctgaggatt tggatgaatt
     3901 aaaagaagta cttcaagaac ctttgtttgc agggattgaa tggattatcg tttcacttgg
     3961 tgccaacggt acttttacca aacatggtga cactttctac aaggtagata ttcctagaat
     4021 tcaggtggta aatcctgttg gatctggaga ctctactgtg gcaggaattt cttcaggact
     4081 tcttcacaaa gaatcggatg cagaattact catcaaggca aatgtccttg gtatgctcaa
     4141 tgctcaagaa aaaatgactg gtcatgtcaa catggccaac tatcaagctc tatatgatca
     4201 attaatagta aaagaggtat aaaatggctt taacagaaca aaaacgtgta cgcttagaaa
     4261 aactttctga tgaaaatggt atcatctcag ctcttgcatt tgaccaacgt ggtgctttga
     4321 aacgcctcat ggctcaacac caaacagaag aaccaactgt ggcccaaatg gaagaactta
     4381 aagttttggt agcagatgaa ttgactaaat acgcttcatc tatgcttctt gaccctgagt
     4441 atggacttcc agcaactaaa gctcttgatg aaaaagctgg tcttctcctt gcttatgaaa
     4501 aaacaggtta tgacacaaca agcacaaaac gcttgccaga ctgcttggat gtttggtctg
     4561 caaaacgtat taaagaagaa ggtgcagatg cagttaaatt cttgctttac tatgatgtag
     4621 atagctcaga cgaactcaat caagaaaaac aagcctacat cgaacgcatc ggttctgagt
     4681 gtgtggctga agatatccca ttcttccttg aaatccttgc ttacgatgaa aaaattgcag
     4741 acgcaggttc tgtagaatac gctaaagtaa aaccacacaa agttatcggt gctatgaaag
     4801 tcttttcaga cccacgcttt aacattgatg tcttgaaagt tgaagttcct gttaacatta
     4861 aatatgttga aggcttcgct gagggtgaag tggtttacac acgtgaagaa gcagcagcct
     4921 tcttcaaagc gcaagatgaa gcaacgaact tgccatacat ctacttgagt gctggtgtat
     4981 cagctaaact cttccaagat actcttgtat ttgctcatga atcaggtgca aactttaacg
     5041 gagttctttg tggccgtgct acatgggcag ggtcagttga agcttacatc aaagatggtg
     5101 aagcagcagc tcgcgaatgg cttcgcacaa ctggatttga aaacattgat gagctcaata
     5161 aagttcttca aacaacagcg acttcatgga aagaacgtgt gtaagaaagt cctcctagtt
     5221 taggaacatg aatctaaaaa aatttaaaaa aagttgtatg taaaggttta caaaataact
     5281 tacttgtgct atacttaaat cacaagttaa tacaaggtga gtgttactaa gtaatattag
     5341 gcatgatcac aggtgaatta gaaatcagct gattttctag ttcatttgtg gtcatttttt
     5401 gtactcatat acctttaaaa tataaaagga ggttgacatg tatcgaattc taaatccaat
     5461 gaatcacaat gtctcgcttg tcagaaatga taagggagaa gaggtgattg taattggtaa
     5521 ggggattgca ttcggaaaga agaaggggga tttgattgct gaaaatcagg ttgagaaaat
     5581 ctttcggatg aagaccgaag agtccagaga aaactttatg gctcttctca aagatgttcc
     5641 gcttgatttt atcacagtga cctatgaaat cattgataag ctatcaaaga aatatcatta
     5701 tccgattcaa gagtatctct atgtaacctt gacagatcat atttactgtt cttatcaagc
     5761 tctaactcaa ggaaggtaca aggatagtaa tctgccagat atttccgcta agtatcctgt
     5821 cgcttttcaa atcgcaaatg aagcttttga aatttaccgt cagaagctag cagatcattt
     5881 tcctgaggac gaaattattc ggattgctta tcatttcatt aatgctgaag gtgaaaatga
     5941 agtggaactt gtggagtcga ttgataagag gaaagaaatt ctcaggaatg ttgaagaagt
     6001 tttaacggac tatgcaattc aacgaactaa aaagaataac catttctatg atcgctttat
     6061 gatccatttg aattatttct tggattattt agacagatct agagatgata accaatcact
     6121 tctggatatg gaagatcata ttaaacaatc ctatccaaaa gccttcgaga ttggttccaa
     6181 gatctatgat gtgattacgc aacatacggg tcttgatttg tataaaagtg aacgagttta
     6241 tctagttcta catatccaac gtttattgtc ataaaaattt atttaaaact atataaggag
     6301 aattctatca tgaatagaga agaagtaaca ttgttaggtt ttgaaatcgt agcctatgct
     6361 ggcgatgctc gttcaaaact attggaagcc ttgaaggctg ctgaagctgg tgattttgaa
     6421 aaagcggacg ctctggtaga ggaagctggt agctgtattg cagaggctca ccacgcgcaa
     6481 acaagtctat tgactaagga agcttctggt gaggacttag cgtatagtgt gaccatgatg
     6541 catggtcaag atcacttgat gacaactatc ttgttaaaag acctaatgca ccatttaatt
     6601 gaactttaca agagaggagt taaataatga ataaactaat tgcatttatc gagaaaggaa
     6661 agcctttctt tgaaaaacta tctcgtaata tctatcttcg tgctattcgt gatggtttca
     6721 ttgcaggtat gcctgttatt ctcttctcaa gtatctttat cttgattgcc tttgtaccaa
     6781 actcatgggg ctttaaatgg tctgatgaag ttgtagcctt tctgatgaaa ccttatagct
     6841 attctatggg tattctggct ctcttggtag ctggtacaac agctaagtca ttgactgact
     6901 cagtaaaccg gagcatggaa aaaaccaatc aaatcaacta tatgtcaaca ttgttggcag
     6961 caattgttgg tttgttgatg ttggcagctg atcctatcga aagtggtcta gctactggat
     7021 tcttgggaac aaaaggtttg ctttcagcct tccttgctgc cttcgttact gtagccatct
     7081 ataaggtctg tgttaagaac aacgtcacta ttcgtatgcc tgacgaagtt ccaccaaata
     7141 tctcacaagt ctttaaagat gtgattccat tcactctatc agtggtttct ctttatgctc
     7201 ttgatttact agctcgtcat tttgttggtt ctagtgtggc agaatcaatc ggtaaattct
     7261 tcgcaccact cttctcagca gcagacggat accttggtat taccattatc tttggtgcct
     7321 ttgccttctt ctggtttgtt gggattcatg gtccatctat cgttgaacct gctatcgcag
     7381 cgattaccta tgcaaatgct gaagtcaact tgaaccttct ccaacaaggg atgcatgcag
     7441 acaagattct tacttctggt acacaaatgt ttatcgttac catgggtggt acaggtgcga
     7501 cattggtcgt tccatttatg ttcatgtggt tgacaaaatc gaaacgtaac cgtgcaatcg
     7561 gacgtgcttc agtagttcct accttcttcg gtgtaaatga accaatcttg tttggtgcac
     7621 ctcttgtttt gaatccaatc ttcttcattc catttatctt tgctccaatt gcaaacgtat
     7681 ggattttcaa attctttatt gaaactcttg gaatgaactc attcactgct aatctaccat
     7741 ggacaactcc agctccacta ggtctagttc ttggaactaa cttccaagtg ctatcattca
     7801 ttcttgctgc ccttctaatt gtggttgacg tagttattta ttacccattc cttaaagtct
     7861 atgatgaaca aattcttgaa gaagaacgtt caggtaagtc taatgatgaa ttgaaagaaa
     7921 aagttgctgc aaacttcaac actgcaaaag cggatgctat tcttgaaaaa gcgggtgtcg
     7981 atgtagcaca aaataccatc actgaagaaa caaatgtcct cgttctctgt gctggtggag
     8041 gtacaagtgg actccttgca aatgctttga ataaggcagc agcagaatac aatgtccctg
     8101 tgaaagcagc agcaggcggc tatggtgctc accgtgaaat gttgccagag tttgatttgg
     8161 ttatccttgc tcctcaagtt gcttcaaact ttgaagatat gaaggcagaa acagataagc
     8221 tcggtattaa acttgctaag acagaaggcg ctcaatacat caaattaact cgtgatggaa
     8281 aaggtgccct agcattcgta caagagcaat tcgattaagg ctaggaactg tgaaacagtc
     8341 tcccatcgtt acggaaatcg ctatggcgaa tttcctaatc gccttattaa ttcgtcggta
     8401 aaaagatatc gtttttacct cctcatgtca caattcagtg acttggtaca agaagtgaga
     8461 tggagaagca tggctcactg actcctctcc tctcactttt actttattta aatcaagaaa
     8521 taggtgaaaa aaatgacaaa aacacttcca aaagacttta ttttcggtgg cgcaacagct
     8581 gcttatcaag cagaaggtgc tacacatact gatggaaaag gaccagttgc ttgggataaa
     8641 tatcttgagg ataactactg gtacactgcc gaaccagcta gtgattttta caatcgatat
     8701 ccagttgacc tcaagctagc agaagagtat ggtgtcaatg gtattcgaat ttctattgct
     8761 tggtcacgta ttttcccgac tggttacggc caagtaaatg ttaaaggtgt tgagttttat
     8821 cataatttat ttgcagagtg tcacaaacgt catgttgagc cctttgtaac tcttcatcac
     8881 tttgacacgc cagaagctct ccactcaaat ggagacttct taaaccgtga aaatatcgaa
     8941 cattttgtag actacgctgc cttctgtttt gaagaatttc cagaagtaaa ctattggaca
     9001 acctttaatg aaattggacc aatcggtgat ggtcaatatt tggttgggaa attccctcca
     9061 ggtatccagt acgaccttgc caaagtcttt caatcacacc acaatatgat ggtgtctcat
     9121 gcgcgtgcag tcaagctata taaagataaa ggctataaag gtgaaattgg tgttgttcac
     9181 gctctgccaa ccaagtatcc tttggatcct aaaaatccag cagatgttcg tgcagctgag
     9241 ttggaagata tcatccacaa taaattcatc ttagacgcaa cttatctagg tcgctattca
     9301 gctgaaacca tggaaggtgt caaccatatc ttatcagtca atggtggtag tttggatctt
     9361 cgtgaagaag attttacagc attagaagct gcaaaagact tgaatgattt cctaggaatc
     9421 aactactata tgagtgactg gatggaagcc tttgatggag aaactgaaat tatccataat
     9481 ggtaaaggtg aaaaaggaag ctctaagtat caaatcaaag gtgttggtcg tcgtgtagct
     9541 cctgactatg taccacgcac ggattgggat tggattatct accctcaagg tttgtatgac
     9601 caaatcatgc gtgtgaagaa agattatcct aactacaaga agatttacat cactgaaaat
     9661 ggtctcggct ataaagatga gttcgttgat aacactgttt acgatgatgg tcgtattgat
     9721 tacgtgaaac aacacttgga gatcttgtct gatgcgattg cagatggagc taatgtaaaa
     9781 ggttacttca tttggtcatt aatggatgtc ttctcatggt caaacggtta tgagaaacgt
     9841 tatggtctct tctacgtaga ttttgaaact caagaacgtt atcctaagaa atcagctcac
     9901 tggtacaaga aagtagcgga aactcagatt atagactagt agaattagtc attagatata
     9961 gaattttagt gagtcaaaaa gatgttcaaa gattttatcc aatctattta tgaaaaagtt
    10021 tatattataa atttcgaaaa atgctctcaa ataccgtgtt tgacgagtga agaattgaaa
    10081 agtcttggaa aatggtatgt ctcgactggt aaagaatgga tttgtcattc agatgatgag
    10141 ctggaagaat ttaaaaatct atttttaaat tttatcaatc ctgaagaata ggatactatc
    10201 tcctttgatt cagattttat gccgtttcaa caatcgtaac caatttctca aaaaagttaa
    10261 atcttatatt tagtactctg caaaactctt atctgatcac gttgcttata ctcaatgaaa
    10321 atcaaagagc aactttaaac taggaagcga gtcgcagatt tctcaatgca tagctttgag
    10381 gaattgggca aaaagtcttt gatatagaaa aaagcatagt atcaggtgtt gaaacacctg
    10441 atactatgct ttttattgtg ggaagattta ctttttttct tctgaaattg agttgttacc
    10501 caggctcttt cagtttatta aggcttgatg actttaatgt gtttagatag cttaaaaagg
    10561 attgaatcac ttagtttaga atctgaaaca atagtatcaa gatttgatac attataaaaa
    10621 gtataaaaat caaacttatt gaacttacta tgatctgcga gtaaatattt tttattagaa
    10681 ttatttaaag cgatgcgttg agcctctccc tcttcctcgc taaaagtagc tagagctccg
    10741 ttttgaatac cattacagct aacgaaagct ttagaaaatt ggagattaga gagattttgt
    10801 agggtcaatg taccaacaaa agcacctgta atatcgcgat aatttccacc tattaaaatc
    10861 aaatctgtta attttcgttc gcttaaaatc agaaaaacag gtagactgtt ggttacgacg
    10921 cggatattgt caataggcaa ctcacgcgca aaaaactcta atgttgttcc tggtccaatg
    10981 aaaatagttt ctctttcttc tactagactg cctgcaaaat gggctatttc ttgtttttct
    11041 gccgtttgga gggcttgttt ttcaatattt gatcgctcat tagtcaaaag ggagttggtt
    11101 cgaagttttt cagctccacc atgcacacga atcagcaaat ctttatcagc taattcctgt
    11161 aaatagcgcc ttgcagtcat atctgaaacg gctatttcgt ccataatctg tttaactgtt
    11221 atggttcctt tactatttac tatctctaaa attttggcta atttttcttg tttgagcata
    11281 ttatcacctc gtttcctact actatcttac cataaacaaa ctcatcattc aaatacaaaa
    11341 acaacaaaat gaaacaaaaa caaaaatatc gaagtttgtt ttcaaaactt tcgatatttt
    11401 tgttgggtta taactttgat gtttctagtt tactttttga tgattgagag tgatggagaa
    11461 ttagtctaaa ccgtagttat agtcatcgtc ttgcatgact tcaacttcgc caagaaggta
    11521 accatttccg acttgagaga agaagtcgtg gttggaagtt cctgttgaaa taccgttcat
    11581 tacgattggg ttgacatcat cagctgaatc tgggaagagt ggatcttgtc ccatgttcat
    11641 gagagcttta ttggcattgt agcgaaggaa ggttttaacc tcttcagtcc aaccaacacc
    11701 gtcataaaga ctctctgtgt agccttcttc attttcataa agagtataga gtaggtcgta
    11761 catccattct ttgagttttt cttgctcttc ttcaggtaat tcattgaaac caagttggaa
    11821 tttgtaacca atgtaggttc cgtgaacaga ctcgtcacga ataatcaatt taatgatttc
    11881 tgcaacgttg gcaagtttgt tgttaccgag atagtagagg ggagtgaaga aaccagagta
    11941 gaagaggaag gtttcgagga agacgctggc aactttcttt tcaagtgggc tgccgtttag
    12001 gtagatttcg ttgacaatct cagccttctt ttgtaggtaa ggattggtat tggtccattc
    12061 gaaaatttct tcaatctcag ccttagtatt caaggtagaa aagattgatg agtaagattt
    12121 agcgtggaca gattccataa attggatgtt attgaaaaca gcttcctcat gtggtgtacg
    12181 gatgtctgcg cgaagggctt gaaccccagt ttcagattgc atagtgtcaa gaagggttaa
    12241 accaccaaaa acttttccga ccaagtcttt ctctttgtta gatagctttc tccagtcatc
    12301 caagtcgttt gataagggaa tacgtgtatc gagccaaaat tgctccgtca gtttttccca
    12361 agttgatttg tcgatgacat cttcgatggc attccagtta atggctttgt agtaagtttc
    12421 catttaaaat ctctttctgt gtttagtatt gcgaactcac aattatttct actttaccat
    12481 aattctatag gagtatcgca caaaaagtcg gaagcccgac ttttaaaatg ttacataaat
    12541 tatgttatga catagtagat ttgattttat cagtgctgct tagggaaaaa tagtgttttt
    12601 atgctagaaa ctaaatcaca cagctttcac attggttggc gccgacttct ccaccgtcat
    12661 ctgtaaaggt acggacgtag tagatagact tgattccctt gttaaaggca tagttacgaa
    12721 ggatggacaa gtcacgtgtc gtttgtttat tttccctctt ccattcgtaa aggccttttg
    12781 gaatgtcact gcgcatgaag agggtgagtg aaagtccttg atccacgtgt tcagtcgcag
    12841 cagcgtaaac atcgatgact ttacgcatat ccatatcgta ggcagaagtg tagtaaggaa
    12901 tggtttctgt agacaagcca gcagcagggt agtagatttt accaattttc ttctcttggc
    12961 gttcttcgat acgttgcgta atcgggtgga tagaagcaga aacgtcgttg atatagctga
    13021 tagaaccatt tggcgctaca gcaaggcgat tttggtggta aagaccatct tcttgaacct
    13081 tgtcgcgaag ttcagcccaa tcagcaacac cagggataaa aacatttttg aagagttctt
    13141 taacacggtc tgatgttgga acaaattcac cagttacata cttgtcaaag taacttccgt
    13201 tagcatagtc tgatttttca aagttgtgga aggtaatacc acgctcacgc gcaatattgt
    13261 ttgactctac caaggtccag tagttcataa gcataaagta gatgcttgta aattcaacag
    13321 actcaggtga accatattca atgagttgtt gggcaaggta gctgtgcagt cccatggcac
    13381 cgagaccaaa ggtgtgggct tggctatttc catggtcaat cgttggtaca gctacgatat
    13441 gtgaactatc tgtaacgaaa gtaagggcac gaaccatagc acggatagaa cgaccaaaat
    13501 caggtgaagt catcatgtta accacgttgg ttgaacccag attacatgaa acatctgttc
    13561 ccatttgaag gaattcttga gcatcgttga tcaagcttgg ttcttgaact tgaagaatct
    13621 cagaacacaa gttactcatg ataatctttc catcaacagg atttgcacgg ttagctgtat
    13681 cgatgttgac tacataagga tagccagact cttgttgcaa tttagagatt tcagtttcca
    13741 aatcccgcgc cttgattttt gtcttgcgaa tatttggatt tgcgaccaat tcatcgtatt
    13801 tttcagtaat gtcgatgtaa ttgaatggca caccgtattc tttttctaca gagtaagggc
    13861 tgaagaggta catttcttca tttttacgag ccaattcgta gaatttatca ggtactacaa
    13921 caccaagtga tagagtcttg acacgtactt tttcatcagc gttttctttc ttagttgaaa
    13981 ggaaagcgat gatatctggg tgaaagacgt tgaggtagac aacaccggca ccttgacgtt
    14041 gccccaattg gttggagtaa gagaagctgt cttcaaaaag cttcataaca ggaacgacac
    14101 ctgaagcagc tccttcatag cctttgatag gtgcaccagc ttcacgaagg ttgctgaggg
    14161 taattcccac accaccacca atacgtgaaa gttgaagagc tgagttgata gaacgtccga
    14221 tagagttcat atcatccgtc acttggatta ggaaacaaga taccaactcc ccacgacgag
    14281 cacgtccagc attcaagaag gaaggagtag caggttggta gcgttggtgg atgatttcat
    14341 tggcaatatc gattgcaaca gcttcattcc catcagcgaa ataaagggcg ttgaagaaga
    14401 cacggtcttc catattttca agatagtatt caccgtcatt agtctttaag gcatattgat
    14461 tgtaaaattt ataagctgcc atgaatgact tgaattggaa gttttggtct ttgataaatt
    14521 gagccaattc ttccaagaac tctggacggt atttcttgat aaaggctgtt tcgatgtagt
    14581 tgtgttcaat gaggtaattg attttgtctt tgattgaatc aaaaaccata gtgtttggaa
    14641 ctacattttc tttaaagaaa gcatccaagg cttccttatc tttatgaagc atgatttgtc
    14701 cattaacagg acggttaatt tcgttattaa gacggaagta agtcacgtct tcaagatgtt
    14761 ttaatcccat aaaatttccc ttatctaatt acaaaagaaa ggcttctaag ttagccctaa
    14821 aagcagtttc ttctggatga tgtactaaga ttatgctaat tgtttcagtt ttcctggttg
    14881 gaaacctgaa aagacttcag ttggtgtttg gataacagga gctgcgctaa aaccgagctc
    14941 tttaacttga tcgacgtact caggttgctc atcaagattg atttcacgat aagagacatt
    15001 attactgtcc aagaaacgct tggtcatttt acattggaca caattgtttt tagaataaac
    15061 ggttaccatt gtgtaactcc tcttcaaaat ttaatactat cttagtatat cagaaaataa
    15121 aa
//
LOCUS       DAVLGK010000045        15001 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLGK010000045 DAVLGK010000000
VERSION     DAVLGK010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15001
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.045"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(1..297)
                     /locus_tag="VXE01_001735"
     CDS             complement(1..297)
                     /locus_tag="VXE01_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750598.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="VXE01_001736"
     CDS             complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="VXE01_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV0750599.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVMN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3571..4797)
                     /locus_tag="VXE01_001737"
     CDS             complement(3571..4797)
                     /locus_tag="VXE01_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV0750600.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWRANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4840..5532)
                     /locus_tag="VXE01_001738"
     CDS             complement(4840..5532)
                     /locus_tag="VXE01_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0750601.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWFLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTKKGLSVDQAYVEHVLPEKMHYNLAYLREFSFLGDI
                     KIMFQTVFEVLK"
     gene            complement(5705..7456)
                     /locus_tag="VXE01_001739"
     CDS             complement(5705..7456)
                     /locus_tag="VXE01_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750602.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7446..9191)
                     /locus_tag="VXE01_001740"
     CDS             complement(7446..9191)
                     /locus_tag="VXE01_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750603.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYTIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAAVEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMAGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9397..9774)
                     /locus_tag="VXE01_001741"
     CDS             complement(9397..9774)
                     /locus_tag="VXE01_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV0750604.1"
                     /translation="MKCLIDGKPTLLIKNGNIDPEACRSVGLSASDVALKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYK"
     gene            complement(9846..10302)
                     /locus_tag="VXE01_001742"
                     /pseudo
     CDS             complement(9846..10302)
                     /locus_tag="VXE01_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10436..11263
                     /gene="xth"
                     /locus_tag="VXE01_001743"
     CDS             10436..11263
                     /gene="xth"
                     /locus_tag="VXE01_001743"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV0750605.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11275..11418
                     /locus_tag="VXE01_001744"
     CDS             11275..11418
                     /locus_tag="VXE01_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0750606.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11418..11657
                     /locus_tag="VXE01_001745"
     CDS             11418..11657
                     /locus_tag="VXE01_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0750607.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12040..12135
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12535..13116
                     /locus_tag="VXE01_001746"
     CDS             12535..13116
                     /locus_tag="VXE01_001746"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV0750608.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGRVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13116..14378
                     /locus_tag="VXE01_001747"
     CDS             13116..14378
                     /locus_tag="VXE01_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV0750609.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14465..>15001)
                     /locus_tag="VXE01_001748"
     CDS             complement(14465..>15001)
                     /locus_tag="VXE01_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HEV0750610.1"
                     /translation="EKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENI
                     VQSYLEAEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYL
                     IEVNFYSGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDIL
                     PFLYNINDLEHNILKNLK"
BASE COUNT         4460 a         3193 c         2767 g         4581 t
ORIGIN      
        1 ttatttcatt ttactatact ctgttaattc atatgagttt aaaccgattt catctttaac
       61 ctcgagtaaa gcagtttcaa atatttgttt aagagttttt gattctttac aattaaccga
      121 caaactttct gataaaatat gtacaacttc tgagactgaa taacctatct cctctttaga
      181 attatataaa tctgtagctc caccaataat ccaaaaatac tgattttgtg aacctacaat
      241 atcctcattt tctacggaac ttccttgtat cgaacaaatt ttatttatct ttaccataat
      301 acttcaaccc ttttagtgtc aaaagtaaac caattcctgt cactgttaag aatagttcca
      361 taatcttgtt cgaaccagtc tttggtaatt tttgttttac atctactatt tctttagatt
      421 tattaatatg attttcagtt tctctgccat ctccaactat tttatagttt acttcttctg
      481 tcttattatc ttgtttattg tcgatcttgt cattcatttg tctattatct ttacttgagt
      541 taaactctcc gttcttctgg ttactatcaa ttacattatt tgaattagat tgtttttcct
      601 ctttgttttt ttctttttcg tttttatcac ttaaattatt tgttacaatt ttgtaaagcc
      661 cattctccgt tacaatattg aaattaccat cgctatcacg tataacaggt tctttcccat
      721 ttgcattaga tttgatgaat gatatatact taccggataa attataaaat tggttattta
      781 aaacggttat tttacccttt gaatcctcaa taacaattcc ttctttacca ccgaatatac
      841 tattctctga gactactaaa ttatcactaa ctcgtaataa ttcaatattt ggttgttctg
      901 tttccttaga attattattc attacatttt ttgttacagt aatatctgat acttttccta
      961 aatattctgc actatctttt gcaactcgta tcgcttttgt tttaggatcg gcaatattaa
     1021 atatattttc ggcgataacc acctgtttat ttaaatctaa taggtcttta gtgtttttat
     1081 agctataagc atttactaaa gctgctccgc tttctcgata atgtacactc tctcctttaa
     1141 ctttcttatc aaagcgattt cctttgatta atacatcagt gaatcctgta aaacgtacac
     1201 ctgcatacat catgttatca aaatgattat ttaaaatttt aatattagag gggttctgtg
     1261 tcgacaatgt ttgatagtgt gtgccaattg ctgttactaa ttccccagat ttatcacttt
     1321 tgccaaaata ggaattttga atagtcacat tttcagattt tttcccatca tcattcaagg
     1381 cataaggaaa accttttcta gttaatggtt caatctgaat gctctcctta cttatgattt
     1441 gcccatcctt catcgttttg ggtaaggctt gcccaagaaa acgagaatta tcaactaata
     1501 catttttcga acctgcaatt tgaatagcat gcccttgata actatccttg aatgttacat
     1561 tttttatagt tacgttattt gaattcccaa tagcaaatgc acctgaagaa tttataagtg
     1621 gtagattttt tgctttagtt ccttcttcat tcaaagcacc gttcatatca atcgtaccac
     1681 cagaataact aatatcttct gttgggcccc attctacttg cgcaccatca tccgtaaata
     1741 aacctgtcat aaaaacaatg gaagggtgat tcttaatatt tataccattt agaattgtag
     1801 ctttctcatt caattctaag tgtgtatgac tttttaaaaa aacaatttct tttactaaat
     1861 aagttccttc aggaaaatat acatttcctc cacctagccc ttgagctgca gcatctattg
     1921 catcttgaat tgcttgtcga tcatcatgaa tcccatcacc taccgcacca taatctttta
     1981 cacttaaagc agtatcttca aattcttttt tgataattct gtcacttata acatcttcct
     2041 tataactctt attttcatta gtagatgtta ctgtagattc aactgttctg ttgtctaatt
     2101 gtgaattgga acgaatagta ccattagagc tgatactatt aacacttaac gaattatcta
     2161 aaccattagt ggttgaatta gaggcaatca tttcagcaga acgattctga ttaacagttg
     2221 gtgaattatc taaatcatta gtaattgcat tagaagactc ttttgtagcc atcggtgaag
     2281 aactagtaac aacttcatcc gataaaatac cttggcttcc caaaattgaa attgccaata
     2341 gtaccgagca agtccccacc tttaatttac gaatactgaa tacctcatta ggaacaaaat
     2401 atttcatcag aacctccaat ttttttacta tttttaacaa ttgattatta cttttcttaa
     2461 aatagataga atgacaccgc tgtcattatc tttatcatat attttccaaa ttgaattgtc
     2521 aaggaataac acaagaaaat attaaaattt atactcttcg gaaatctctt caaactaggt
     2581 cagtgccgcc ttgccctaag tctaggttac tgacttggtc agttctatag tagactgaaa
     2641 ctataatagt acacctctac ttctaaaaca ttgttagaaa tcgatttgac tgtcccgatc
     2701 gatttgtcct attcttattt ccttttacta tatctacaac ctcaaagcag ggttttgagc
     2761 tatctatggc caacttccta gtttgctctt tagccttcca ttcaaaagtg atgctatctt
     2821 tcttagcttg aatataaaat atcccattta ctatatttaa atttattgat atgttgtaaa
     2881 ttataaatga aagaacaaat accttgtcat acaagcattc gccagggata tttacatgaa
     2941 tatcgctcat atggcggatt gaaactaaaa cactacaata tatttcttaa atagaccttc
     3001 tataaaagct agatttaacc tcgataaaaa tagatgcagt gcttctaaaa tactggaata
     3061 gggcatatag gtaatagtag acaagtgttt tatagattgt ctcgcaggag atctaatgat
     3121 gtatagcaag catcactaaa catatagaat atttgcatta ttataatatc aacatgttat
     3181 aaattctatc atgcaaaaga atgactagaa catgaaagac aggcacaaaa ctttgaacaa
     3241 tattctgaaa acaaaaaaaa gacgcgagtt tccacaatct cactcatgga aactcacgtc
     3301 tttcaaaaaa tagggtgaat tgaaaactag aacaagacac tagattttct aaatgatgtc
     3361 tagtaaggat tctaaatgct acaccaaatt gctcacatct tatttcaaac cacgggactc
     3421 ccacaagaaa ggaaaatcct ataaaaattc tctctctgag gagaaagagg cctcaactac
     3481 aggtgtaaac tattatcaat tgaaaacaac agtttttaca ctcaattaga ctttttaggg
     3541 ataggatcac tttcgcttga ctgtagtttg tcattttttt gataaagtta gcactttttc
     3601 agaaactgtt ttgaaagtct caatgatata gtctacttct tcatcgctta atttagtatg
     3661 aagagggagg gtaatttcat tctcaaagaa ggcataggct ttaggatagt tcgtcatatc
     3721 aaatccaaga ttcttatagg ctgtcaagag aggaagcggt ttgtagtgaa cattacttgc
     3781 aattcctgct ttagccaatt cttggatgat gaggttgcgt tcttctaggc ttgctccttc
     3841 tacacgggtg atgtagaggt ggcgtgaaga ttcgacagtt tcagtcttgt gtgccaaagg
     3901 atggatgcga gaacctgcaa aaccactatc atagcggtcc acaatgtcct tacggcgttg
     3961 caacaaactt ggatagcggt ccaattgtac caaaccaagt gaagccatga tatcggtcat
     4021 gttgcactta taggctggtg taacgatatc gtattcccat gaccccagtt gcatcttggc
     4081 aagagcatcc ttagtttgcc cgtgaaggga aaggatttgg aattccttgt acatctcttc
     4141 gtcatcaatc actggattgg ctctccaagt cgcacttcca ccttctgccg ttgtaaagtt
     4201 cttaacggca tggaatgaga aggaagtaaa gtcagcgata gaaccagaag gttgtccttt
     4261 ataagtagat cccaaagcgt gggcactatc agagacaatg acaatacggt taaaggcctt
     4321 ttgccacttg cttgaagcag taaagaagtc acgttttttc tccacgactt ggaacaaacg
     4381 gtcataatcg caaacaatcc ctgcgagctc tactgggata atcaccttag ttttctcagt
     4441 gatagcttgc tcaagcaggt catagtccat ctcaaacgta tctgcttgga tatccaccat
     4501 gacaggggtt gctcccacgt gcgtaatgac actacatgaa gccgtatagg tcatggctgg
     4561 aacgatgact tcatcaccag gtcccacttc caaaacgcgt aaaatcaact ccagagcggc
     4621 tgtcgcagag ttgagacaaa cagtcttagg tgtctgtgtg taaagagaca agcggcgctc
     4681 cagttctttt gttttaggac ctgttgtgat ccaaccagaa cgcagggtat ccgctacttc
     4741 agcaatttct gcttctgtga tatcaggcgg tgaaaatgga atattgtaat ttggcattga
     4801 tttgctcctt ttatctgtac tcattttctt atgactactt tattttagta cctcaaatac
     4861 ggtttgaaac atgattttga tgtccccaag gaaactaaac tctcggagat aggcgaggtt
     4921 atagtgcatc ttttcaggaa gaacatgctc cacataggcc tgatcaactg acagaccttt
     4981 cttcgtcatt tgactgatga tggtgtcctc atccttgtag ttgatgctgg ctggagaggt
     5041 aatccctgct tgcaagagca aggttgccat catttcaggg ctatactgct ctgtataacg
     5101 tggcacttca ggtcgtgtac cgacaaagga catctcacct ttaaggacat tgaccaactg
     5161 aggcagttcg tccaaacgga cacgtcggat gaaatttcca accttggtaa tacggctatc
     5221 gttagcagaa gtcaccagac ttcctttttt atccgcatcc gtcaccatgg tacggaactt
     5281 ccaaatcttg aaccgacggt tgtactgggt cacacgctct tgcttgtaaa tcactggccc
     5341 cttactatcc aacttgatcc aaatgctcaa gatgagaaag atgggagagg ttagaaccag
     5401 taagaccaag gccaaaaacc agtccaagca acgcttgaaa atcagcgaac ccttcctttt
     5461 agagacaagc tggtagtaag actcaacctc gcttgatttc atttccacag gcaagtcttc
     5521 ccatttcagc atgctgttct cctttgtttt tattatacta tttgtcaaca tttttcatta
     5581 taccacaaaa tggaaaaggc ggtgaaagaa atctgtaatt tgaaggattt ccttctagta
     5641 ctcaatgaaa atcaaagtac agctttgaga ttgcagataa agctgacatg gtttaaagag
     5701 attttcaaag agtataggcc atggcccctg cctgcaaact atacatcttg tgataggttc
     5761 ctcccagagc caagagttcc tcatgggttc cactctcgat aatgcgtccc ttatccaaga
     5821 catagatgca gttggcgtct tgaatagtag aaaggcggtg agcgatagca atagttgttc
     5881 ggccctgtct catcttcgcc agagaagctt gaaccaagct ttctgtttca gagtcaatat
     5941 tggctgtcgc ttcatccaaa atcaggattt taggctggct ggcgactgtt ctagcaaagg
     6001 caagaagctg gcgctgccca gtagagaagc tcgaaccacg ctcggaaaca ggggagtcgt
     6061 acccctgagg aagttcttga ataaaggaat ctgcatccac aaaggctgcc gcagcctgaa
     6121 cctgctcatc actgatttct tggtacatgg cgatattgga cttaatagtt ccatgataga
     6181 ggaagggttc ctgtaaaacc aaaccgatgt tttttctcag ctcttcttga ctgaaatccc
     6241 tgatatccac atcatccaag agaactctcc ctgactggaa ttcataaaag cgcatgagga
     6301 cattgataat agacgatttc cctgaacctg tatgacctac aaaggcaatg gtttcaccct
     6361 tattaacaga gaaagaaatg tcatccagaa tcggatgttt accgtcatac gagaaacaca
     6421 catgttcaaa acggatattg ccttctttga ctttagcctg cccattttct tgaagaggtt
     6481 cataggtcct ctcatcgatt aaggcaaaga cacggcctgc agaaaccata gacgtttgca
     6541 gagttgaaaa gttttgcgtc acctcaatca aggggtcaaa aaggcggttg atgtactgga
     6601 taaaggcata catggtcccg accgttatcc cgatagaaag accacgatag ccaaaatagg
     6661 ccatcaagac agcataacct agaagtttca acaaactcat ggcaggtctc aaaaagaggg
     6721 catccaaggc tacagaacgg ttggcataga ccaagtgctc ttggttgatt tcatcaaatt
     6781 ctgcctgcag gcgcttctct tgattaaagg cctggattat tctgattccc tcgatattct
     6841 ctgccagctt actattgata tctgacaaga gacttctggt tttctcgatg attttcactg
     6901 acttttttcg atagagattg accaaaagga aaatcaaagg gagaaagagc aagactaaag
     6961 ccgtcaaacg aaaatccagc accaacatgg tataaagggt tgtcagaaag ataaaaactg
     7021 ctgagataaa gctggataaa atcccagaaa acatatcact aatcgtctcg gtatcgttgg
     7081 tcaaacgaga aacgatagaa cctgctggcg tcttgtcaaa gtaagacatg cccagtttct
     7141 ccatattggc aaaggcatcc cgacgaatat ccctaacaat actgtaagac acgcgcgcaa
     7201 agagaagatt gccgacatac tgaactacag tttgtaggat gtagagacca tagtagacca
     7261 gcaaaacggt aacggctagt tggttaagat tgctgagata ctggtcgata aagtgggaag
     7321 ccacgagggg tatgacactt ttaatgaccg tcgtcgctag gagaaaactg agtgccaaaa
     7381 aggtcaggag tccataaggc ttgagataag acatcaagcg cttcaataca gcccattgtt
     7441 cttgtttatt ctgcatcttc ttctcctttc atttccaact gctgagactg gtaggtttgg
     7501 gcataccagc cagccatcgc tagcaagtct tcgtgcctgc ctctttcgat aatttgacca
     7561 ttttgtagaa ctaaaataaa atctgcatgg acaacagcac tgaggcgatg ggcagtgata
     7621 atggttgtct tgtcctttcg cgtctccttg aggttgtcga taatcgcata ctctgtcttg
     7681 gcatctacgg cggataagga atcatctaaa atcaagatat cagggtctaa aatcatagcc
     7741 cgactcatag ccaaccgttg cttttgacca ccagaaagac tgactccttt ttcaccaatc
     7801 agcgtatcaa atccttgagg catgtctaca atatcttggt aaactcgggc tagcttagta
     7861 gcttccacgg ccgctgaaag gggcaagtta ggattgccaa agcggatatt gtctaggatt
     7921 gaagttgcaa agagaaactg gtcctgagga acatagccca tgagactgcg aaggtctgtc
     7981 agacgatagt cccgaatatc gtgaccgttt agataaatgg cacccttatc cacatcgtat
     8041 tcacgcaaga ggagcttgat taaggacgtt ttcccagagc ctgtctgccc aaccaagccc
     8101 agtgtttgcc cttttgccaa actaaagtga atatccgtca gtgtttcctc attttcaaaa
     8161 gcaaagctgt caatggtata ctccaaacgc ccattttcaa taccatccag aggaaactca
     8221 gggtcttgta caggagattc ctgagacaaa agattttcaa tccgctggta agaaaccttc
     8281 cctcgctgag tagtattaaa gaggaagccg atggccataa gaggccagac cagcatatcc
     8341 aaatagctga taaaggtgac tagattacca actgtaatct gcccttcctg aaccatcaag
     8401 gagccaacca aaagcgttaa aacataggac gaaccaacaa acaagagaac catagggtca
     8461 aagagactat catatttcat ggtttgcagg ttcttttgga aggttaattc attgactgcc
     8521 tgaaaagact tcaactcgtc tgcctgataa ccgaaagact tggtcacttt gatacctgat
     8581 acggactcct gtaccttgtt attgagttca gaaaaagcag cttgggattc gccaaaggcc
     8641 ttatgagtct ttctccctag gcgactagtc gcataggcca tgaaaggtag ggggagaatg
     8701 gcaacaagag tcatctgcca tgagatgcta aagagcatgg tcaacaaagt caccagagcc
     8761 gtgatagagg catccaccgc agacatgaca ccgccacctg ctaaacgagt caaggcattg
     8821 atatcattgg ttgcgtgtgc catcagatca cccgtccgat aggtttgata aaaggctgac
     8881 gacatttttg tgaaatgctt aaacaagcga gaccgcatga tctgtcccaa gcaataagag
     8941 gtcccaagga tatacatacg ccacacatag cgcaaatagt acataccaaa ggctgcaagt
     9001 agcaagtaaa ataggctaag aaggaggtcc tgctgggtta attgccccga tgtgatggca
     9061 tcaatgactc gccccataac cataggagga atgagattga ggacggaaac caagaccagg
     9121 gccacaatcc cgactagata acggcgtttt tctaacttga aaaaccacca gagtttttga
     9181 ataatggaca taaaatccct ttctgattgc aaatggaaac ctgaggccaa tactcaatga
     9241 aaatcaaaga gcaaactagg aaactagccg caggctgctc aaagcactgc tttgaggttg
     9301 tagatagaac tgacgaagtc agtaacctac atacggcaag gcgacgttga cgcggtttga
     9361 agagattttc gaagagtaca agaccccagg tttttcttat ttataagtta cgactgtaac
     9421 agcacccttg tcatattcag caataaagat attggctaca ttgtcatgcc cttgtttact
     9481 gaggttatca agcaaccact cttcgctacg accaatcgat tccaagacat ctacttgaat
     9541 cacaccgtca gtcacaactg gatacttagg attttcatct cccatttgca caacgatgag
     9601 ttgcccattt tgctcttgca cagctcgttt gacttgcttc atctggaaaa tcccttggct
     9661 acgaagtttg agggctacat ccgatgcaga caaaccaact gaacgacagg cttctgggtc
     9721 aatattccca tttttgataa ggagagttgg cttaccatca atcaaacatt tcacaaagtg
     9781 aacattgttg ttgagctatt tgagagtcaa gaccagtttg attaaaattt cgatataatt
     9841 aagtgtcatt tgttcacatc caccagttca attgcgtctg tcttatacaa ttcgactttc
     9901 tctaacaggt acttgtctgg ctcacttccg tttagggcac gataatagcg atctcccacc
     9961 ttgataagtg cgccatctgt gtttgtggaa gtattaacat agacttctga cttgtctact
    10021 cccaaatctt tggaaacaac ctcgatgaaa tgaagtgaag tttgaaattt attgttagaa
    10081 acttgattgt tttgataagt cgtgatgctg accaaaagca gagctaaata aggccagagc
    10141 tgaaatcatg accaactcac gaaattcggt tcccttttta tcatggtatg ccttaaaagc
    10201 aaaaaaaact gtcacagcta atagaacaat cccaaagcca accatgatac cattttgctg
    10261 accgatttgg ctgagtacat agtcataaga gtagaatttc atgtattttc actccctttc
    10321 ataaaatcat tcttaattat aaacgaaaga gagtaatttt tcaaactata cgttggggaa
    10381 atagatcttt ttttggtata ataaaatcta taatctgaat gaaaaaggta actttatgaa
    10441 acttatctca tggaatattg attccctaaa cgctgcccta actagtgact cagctcgtgc
    10501 caaattgtcc caagaagtcc tacaaacctt ggtcgctgaa aatgctgata tcattgctat
    10561 ccaagaaacc aagctttctg ccaaaggacc tacaaagaaa cacgtggaaa ttttagaaga
    10621 actcttccca ggctacgaaa acacgtggcg ttcttcccaa gagcctgccc gtaaaggcta
    10681 tgctggaacc atgttccttt ataagaaaga acttacacct acgatcagct tcccagaaat
    10741 cggtgcccct tctaccatgg acttggaagg ccgtatcatc actctagaat ttgatgcatt
    10801 tttcgtaacc caagtttaca ctccaaacgc tggtgacggt ctcaaacgct tggaagaacg
    10861 ccaagtctgg gatgttaaat atgctgagta tttggctgaa ctagacaaag aaaaaccagt
    10921 ccttgcgacc ggtgactaca acgtagccca caatgaaatc gaccttgcaa atcctgctag
    10981 caaccgccgt tcacctggat ttactgacga ggaacgtgct ggatttacca accttttggc
    11041 aactggattt acagacacct tccgccatgt tcatggcgat gttcctgaac gctacacttg
    11101 gtgggcacaa cgcagcaaaa cttctaaaat caacaataca ggctggagaa tcgactactg
    11161 gctcacaagt aaccgtatcg ctgacaaggt cactaaatct gatatgattg actcaggtgc
    11221 tcgccaagac catacaccga ttgtcttgga aattgacttg taaggatttt ctatatggac
    11281 tacaatgcgg tcattcccga gtttcttgta tcgaatatcg aacagtcccg gtccttctac
    11341 tgtggtttac tgggttttag gattgaatac caacgtccag aagaaaactt tctctttctc
    11401 ttgaagagtg tcaactaatg ttagaggagg gaacaaagga tcaactagct gaactgacct
    11461 acccctttgg tcgtggagtc aatctctcct ttggcataaa ggatgttcca aaactctatc
    11521 aaaaagtgat ggaggcaaac tatcctattt atcgtccctt gaccaaaaga aagtttcgtg
    11581 tcagtgatcc ctatatctat cctcataaat ttgcagtttt ggatccagat ggctattttt
    11641 taagatttag cgagtagaat aataaaaatt gggaaaagtc tttaaagtta gaaaaaggca
    11701 tattgtcagg tgtctaaaaa cttgatagta tgccttttat gatagaaaaa tcttctaata
    11761 ctcttcgaaa atctcttcaa gccacgtcaa cgtcgcctta ccgtaggtat atgatactga
    11821 ctctgtcaat tctatccaca acctcaaaac agtgttttga ggttgtggat agcttcctag
    11881 tttgctcttt gattttcatt tagtataaat gttagcttac aatggagttt ttgttcaccc
    11941 cctcttctgt ttgttcgttt tttaaaccaa aacactaaca aaatagttga tttataaagt
    12001 tatttagtgt aaaataaaaa cattggctca agcctattta aaattgaata tcgttttact
    12061 tgtttatgtc gtgaattggc acgacgtttc tacaaggtgc cggaacacct aacaataagt
    12121 aagtcagcag tgagatatgg ccgtttttgc catgtctatt taggggactt acttagagat
    12181 taagtaggtc ttttttgaat atttttaata tttcccttaa ttagtgcgga cgggaggtga
    12241 aattatcctg tgaataattt caggaatcca gggaatttca tccctaattt ttgagcccct
    12301 agctctttca tttctaggct taggctaaaa tagttccccg aactatttta ctctcaaaaa
    12361 tcccgtcata gacaataaca agattattgt ctatgatacc actacaacgg gaaatatttg
    12421 ataagactcg cttcgctcgt aatagtttta tcaaatatat agtattagca aaagggatca
    12481 ctatagaaat atttaaacaa caagtaaatt aacttttaga ctttaggagg tcttatgaaa
    12541 ttattagaag agcgcatcct caaggatggg catatcttgg gtgataacat cctcaaggta
    12601 gattcctttt taacccacca agttgacttt agcttgatgc gagagattgg tagggttttt
    12661 gcggaaaaat ttgctgctac tggcattacc aaggtcgtaa ccattgaagc gtcgggtatt
    12721 gccccagccg tttttacagc tgaagcctta aacgttccca tgattttcgc caaaaaagct
    12781 aagaacatca ccatgaacga aggcatctta actgctcaag tctactcctt taccaaacag
    12841 gtgaccagca ccgtttctat cgctggaaaa ttcctctcac cagaggacaa ggttttgatt
    12901 atcgacgatt tccttgctaa tggccaagct gctaaaggct tgattcaaat catcgaacag
    12961 gccggtgcca cagtccaagc tatcggtatc gtgattgaga aatccttcca agatggccgt
    13021 gatttgcttg aaaaagcagg ctaccctgtc ctatcacttg ctcgtttgga tcgttttgaa
    13081 aatggtcagg tcgtatttaa ggaggcagat ctctaatgca aactcaagaa aaacactcgc
    13141 aagcagccgt tcttggcttg cagcacttac tagccatgta ctcaggatct atcctggttc
    13201 ccatcatgat tgcgacagcc cttggctatt cagctgagca gttgacctac ctgatttcta
    13261 cagatatctt catgtgtggg gtggcaacct tcctccaact ccaactcaac aaatactttg
    13321 ggattggact cccagtcgtt cttggagttg cattccagtc ggtcgctccc ttgattatga
    13381 ttgggcaaag ccatggtagt ggcgctatgt ttggtgccct tatcgcatct gggatttacg
    13441 tggttcttgt ttcaggcatc ttctcaaaag tagccaatct cttcccatct atcgtaacag
    13501 gatctgttat taccacgatt ggtttaacct tgatccctgt cgctattgga aatatgggaa
    13561 ataacgttcc agagccaact ggtcaaagtc tcttgcttgc agctattact gttctgatta
    13621 tcctcttgat caacatcttt accaaaggat ttatcaagtc tatctctatt ttgattggtc
    13681 tggttgttgg aactgccatt gctgctacta tgggcttggt ggacttctct cctgttgcgg
    13741 tagctccact tgtccatgtc ccaactccac tctactttgg gatgccaacc tttgaaatct
    13801 catctattgt catgatgtgt attatcgcaa cggtgtctat ggttgagtca actggtgttt
    13861 atctagcctt gtctgatatc acaaaagatc caatcgacag cacgcgcctt cgcaacggtt
    13921 accgcgcaga aggtttggcc gtacttctcg gaggaatctt taacaccttc ccttacaccg
    13981 gattttcaca aaacgttggt ttggttaaat tgtcaggcat caaaaaacgc ctgccaatct
    14041 actacgcagc tggtttcctg gttctccttg gactgcttcc taagtttggt gcccttgccc
    14101 aaatcattcc aagctccgtc ctcggcggtg ccatgctggt gatgtttggt tttgtatcta
    14161 ttcaagggat gcaaatcctc gcccgagttg actttgctaa caatgaacac aacttcctta
    14221 tcgcagctgt ttcaatcgct gcaggtgtcg gtctcaacaa cagtaatctc tttgtcagca
    14281 tgccgacagc cttccaaatg ttcttctcaa acggaatcgt cgtagccagc ctactcgcca
    14341 ttgtcctcaa tgccgtatta aatcataaaa agaaataaga aaaagaggtg cgagcctctt
    14401 ttttgtttat cacaaattga ttataaatac aatcaatccc aattcccatc taattgaatt
    14461 ggacctattt caaattcttt aaaatattat gttccaaatc gttaatatta tataagaatg
    14521 gtaaaatatc aaatgtttct cgtaaattat tcttagcctt ataccaacct tgtccatcag
    14581 taatccacat aaactcaaca ttaggaatag ctttagtttc ttcagcaatc attttgtaag
    14641 atctagccgt ctcatttaat tttgaaccac ttcctgaata aaaattaacc tcaatcagat
    14701 aaagcacttg ttcatttttt atgacaaaat caaaacgttt cacagtattc ccatcattcg
    14761 taatagcaga taaatcgaca gaaaaaattt cctctatttc attttgttca atctctttaa
    14821 ataaattctc tcctaaaata tacccttcag cttcaagata gctttgaaca atattttcca
    14881 tcgcatctcc agtccgattt ttgcgcccat tagtatccat accaacctca acacctgtaa
    14941 cgtagtcaac taaatttgat actaaatgat tttgcaataa atcaaatata cctgattttt
    15001 c
//
LOCUS       DAVLGK010000046        14964 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLGK010000046 DAVLGK010000000
VERSION     DAVLGK010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14964
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.046"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            127..990
                     /locus_tag="VXE01_001749"
     CDS             127..990
                     /locus_tag="VXE01_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0750611.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            1373..1993
                     /locus_tag="VXE01_001750"
     CDS             1373..1993
                     /locus_tag="VXE01_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750612.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            2079..2522
                     /gene="tsaE"
                     /locus_tag="VXE01_001751"
     CDS             2079..2522
                     /gene="tsaE"
                     /locus_tag="VXE01_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV0750613.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2512..3030
                     /locus_tag="VXE01_001752"
     CDS             2512..3030
                     /locus_tag="VXE01_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0750614.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            3038..4054
                     /locus_tag="VXE01_001753"
     CDS             3038..4054
                     /locus_tag="VXE01_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0750615.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4138..5394
                     /locus_tag="VXE01_001754"
     CDS             4138..5394
                     /locus_tag="VXE01_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV0750616.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5449..6615
                     /gene="recA"
                     /locus_tag="VXE01_001755"
     CDS             5449..6615
                     /gene="recA"
                     /locus_tag="VXE01_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV0750617.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            6922..8292
                     /locus_tag="VXE01_001756"
     CDS             6922..8292
                     /locus_tag="VXE01_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0750618.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8668..9624
                     /gene="lytA"
                     /locus_tag="VXE01_001757"
     CDS             8668..9624
                     /gene="lytA"
                     /locus_tag="VXE01_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0750619.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            9983..10144
                     /locus_tag="VXE01_001758"
     CDS             9983..10144
                     /locus_tag="VXE01_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0750620.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            10131..10337
                     /locus_tag="VXE01_001759"
     CDS             10131..10337
                     /locus_tag="VXE01_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750621.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            10383..10742
                     /locus_tag="VXE01_001760"
     CDS             10383..10742
                     /locus_tag="VXE01_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750622.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKETVLG"
     gene            10871..11296
                     /locus_tag="VXE01_001761"
     CDS             10871..11296
                     /locus_tag="VXE01_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750623.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEGASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEYMTTGDILIEAFKA"
     gene            11704..12498
                     /locus_tag="VXE01_001762"
     CDS             11704..12498
                     /locus_tag="VXE01_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750624.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            12502..12699
                     /locus_tag="VXE01_001763"
     CDS             12502..12699
                     /locus_tag="VXE01_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750625.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            12689..13240
                     /locus_tag="VXE01_001764"
     CDS             12689..13240
                     /locus_tag="VXE01_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750626.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATFIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAP"
     gene            13299..13559
                     /locus_tag="VXE01_001765"
     CDS             13299..13559
                     /locus_tag="VXE01_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750627.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
     gene            complement(14297..>14964)
                     /locus_tag="VXE01_001766"
     CDS             complement(14297..>14964)
                     /locus_tag="VXE01_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0750628.1"
                     /translation="PKLSLEDLLMATLQYVREYRTYEEIAADFGVHESNLIRRSQWVE
                     VTLVQSGVTISRTPLSSEDTVMIDATEVKINRPKKQLANDSGKKKFHVMKAQAIVTSQ
                     GRIVSLDITVNYCHDMKLFKMSRRNIGQAGKILTDSGYQGLMKIYPQAQTPRKSSKLK
                     PLTAEDKACNHALSKERSKVENIFAKVETFKMFSTTYRNHRKRFGLRMNLIAGIINHE
                     LGF"
BASE COUNT         4711 a         2422 c         3176 g         4655 t
ORIGIN      
        1 atttttatgt aatttttgac tttttttagt ttattaccat aaagaattat ttattccttt
       61 aacttgctat tttgaactaa aaattttata atgcaattaa gcaaatagga aggtttatta
      121 tctttaatga atacactcgc agagaaattc agattgaaaa gaaaagagtt gagactctcc
      181 caacaaactc ttgcagaagg aatttgtgaa caaagccaga ttagtaaaat tgagagaggg
      241 catttcattc cctccgcaga ccttttgttc aaactctctc aacgacttga agtaccatta
      301 gattattttt ttaatgaaca aattgaaatt aaatctaacc tctctaattt caagcaattg
      361 tctgctcgac tattagacga tagaaattat gacgatttgg aatatattta tagaatagag
      421 attgaacgaa gtacttttct aacactagaa gaccgaactt accttgaatg gattaaagct
      481 attattgact tctatcaata tgacagtaag tgtgaggcaa tttcttcatt ggaaaatata
      541 ttattaaaag tctcttcaaa tactctgatt tatttaaagg cgttgaatac tctatctaat
      601 ttctattcct tagtgggtcg tgaacaagaa tatgaggcaa actactctca tttaatagag
      661 ttgtatcaga caaaaaattt ggaccatcaa gagtttttat ttggctacat cagagttcgt
      721 tacaactacg ctcactacct agtatcaaag gaaaaatata atgaagccat ccaagaagct
      781 cttgaaacga ttgaactctg taaacaaaga cagacaagct accaattggc tcctctactt
      841 attcttgtag gaaatgctgg agccaaattt ctagacagag aacaagtcaa aaattattat
      901 atagaagcaa gagagctatg caagatttat aacaatcctt taatgctgat gaagatagaa
      961 aattatttga aggaactaga tactgtttag ttaatcttga cattatagtt tttctgaaac
     1021 gttaaataac ctgtaaggct gatagttaga ttaatactat cagccttata attatgtgac
     1081 tctgagtccg tctcgctccg tgaggtgcga gacaaaacaa ccacccgttt gacggatttt
     1141 catgatttca aatctatatt cttcgaaaat ctcttcaaat cacgtcagct ctatctgcaa
     1201 tctcaaaaca ctgttttgag caacctgtgg ctagctacct agtttgatct ttgattttca
     1261 ttgagtatta gtctctagtg tttgtttagc gtcttaaaga gacatttgag aagattagaa
     1321 acagttctct cttttctcct agtataatga ttggtaggaa gggagagaga agatgaaatc
     1381 aatgagaatc ttatttttgt tagctttaat tcaaatcagt ttgagtagct gtttcctatg
     1441 gaaggaatgc atcttgtcct ttaaacaaag tacagctttt ttcatcggaa gcatggtttt
     1501 cgtttcagga atctgtgctg gagtaaatta tctttatacc cgtaagcaag aagtccatag
     1561 tgtcctagcc agtaagaagt cggtgaagct tttttacagt atgttactct taattaattt
     1621 gttaggagct gttcttgttt tgtcagataa cttgttcatc aaaaatacgc tgcagcaaga
     1681 attagttgac tttttattgc catccttctt tttcctattt gggctagatt tgctgatttt
     1741 tttacccttg aaaaaatacg tgcgcgattt tcttgctatg ctagacagaa aaaagacagt
     1801 gttggtgact attttagcaa cacttctttt cttaagaaat ccaatgacca ttgtctcact
     1861 tctgatttat attggactgg gcttgttttt tgcagcctat cttgtcccaa attcggttaa
     1921 gaaggaagtt tccttttatg gtcatatttt ccgagatctt gtattggtca ttgttacgct
     1981 cattttcttt tagagaaagc ctgtttttta tggatgttat gatgataagt ttagtaggaa
     2041 aatagacaca aaagaaaagt ttttggtata ataagagtat gtacacaaaa aatgaagaag
     2101 agttgcaagc cttaggggag cgtttgggcc atctattagc aaagaatgat gttttaatct
     2161 taactggaga actgggtgca ggtaaaacga cctttactaa aggacttgca aaaggattac
     2221 agatttctca aatgattaaa agtcccacct atactatcgt gagagagtat gaaggtcgac
     2281 ttccacttta tcacctagat gtttatcgta ttgaaggaga tgctgattct atcgacttgg
     2341 atgagtttat ctttggtggt ggcgtgactg ttattgagtg gggaaatctc ttaggagatg
     2401 ccttgccaga tgcttattta gaattggaaa ttctaaaaga agcagatgga cgccgtttaa
     2461 attttcaggc aaagggtttg cgtgctgaga aattgttaga ggagcttcaa tatggagtat
     2521 gaattgctca ttagggaagc agagcccaaa gatgcagctg aattagtggc ctttttaaat
     2581 cgtgtgagtt tggagacaga ctttaccagc ctagacggag atggtattct cttgactagt
     2641 gaggagatgg aaatattcct caacaagcaa gctagttcgg acaatcagat aaccttactt
     2701 gcattcttaa atggcaaaat tgctggtatt gtaaatatta cagctgatca gcgtaagaga
     2761 gtccgtcata ttggagatct cttcattgtg attggaaaaa gatattggaa taatggcttg
     2821 ggaagtttgt tgctagaaga agcgatagag tgggcacaag caagtggcat tctgcgtcgt
     2881 ctccaactga ctgtccaaac tcgtaatcaa gcagcagtcc atctttatca aaagcatggc
     2941 tttgtcattg aaggtagcca agagcgtggg gcatatatag aagaagggaa atttatcgat
     3001 gtttacttga tgggtaaact gataggttag tagaaatatg gttaaaaaaa ttattggaat
     3061 ggtgctagct ttactttctg taactgtagt aggagtaggt gtttttgctt atactattta
     3121 tcaacaaggg acagaaacct tagctaaaac ctataaaaaa atcggcgaag aaaccaaggt
     3181 tattgaagcg actgaacctc taaccattct gttaatggga gtggacaccg gaaatgttga
     3241 acgaactgaa acttgggtcg gtagaagtga tagcatgatc ttgatgacag tgaatcctaa
     3301 aacgaaaaaa acaacaatga tgagtttaga gcgggatatt ctgacgcgca ttgaatcagg
     3361 gaatggtcag gctcatgaag cgaaactgaa ctcagcatat gcagatggtg gagcagagct
     3421 tgctatagaa accattcaaa aaatgatgaa tatccatatt gatcgctatg tgatggtcaa
     3481 tatgagaggg ttgcaaaaac tagtggatgc agtaggaggt attacagtca ataatatcct
     3541 aggtttccca atttctatca gtgaccaaga agaatttaat actatttcta tcggtgttgg
     3601 ggagcaacat attgggggag aagaagccct agtctatgca cgaatgcgtt accaagatcc
     3661 tgagggggat tatggtcgtc aaaaacgtca acgtgaagtt attcaaaaag tcatggaaaa
     3721 agctctcagt ttaaatagca ttggtcatta tcaagagatt ttaaaagctt tgagtgacaa
     3781 tatgcagacc aatattgatt tgtctgcaaa aagtatccct aacttgctag gctataaaga
     3841 ttcatttaaa accattgaaa ctcagcagtt gcagggtgaa ggagagatac ttcaaggtgt
     3901 ttcttaccag attgtttcga gagcacatat gttggaaatg caaaatatac tccgacgttc
     3961 tttgggacaa gaagaagtta ctcagcttga aaccaatgcg gttttatttg aagatttatt
     4021 tggcagagca cctgttggtg atgaagataa ttaacttttg atacaaataa aaaatcaatc
     4081 gtaggaaaat tcctgcgatt ttttcaaaaa aatacgaata gataggtagg aggaaacatg
     4141 aaagcagaaa tcattgctgt tggaacagag attttgacag gacagattgt caacaccaat
     4201 gcccagtttt tgtcggaaaa actagctgag attggggtag atgtatattt tcagacggct
     4261 gtaggagaca atgaagttcg tctcttgtct ttgcttgaga ttgccagtca acgtagcagt
     4321 ctggtgattt tgacaggcgg tttggggcca actgaggacg acctaaccaa acaaacccta
     4381 gctaaatttt tagggaaagc attagtcttt gatcctcagg ctcaggagaa gttggatatc
     4441 ttttttgccc tgcgaccaga ctatgcccga acaccgaata acgaaagaca agctcaaatt
     4501 gtagaaggag cgattccact gccaaacgaa acaggactgg ctgttggagg aaaattagaa
     4561 gtagacggag tgacctatgt cgtccttcca ggtccgccaa gtgaattgaa acccatggtc
     4621 ttaaaccaac ttctacccaa gttgatgaca gggagcaagc tgtattcccg agttcttcgt
     4681 ttctttggga ttggcgagag ccagttggtt acgattttgg ctgatttaat tgataatcag
     4741 atcgatccta ccttggcccc ttatgccaag acaggagaag tcactctacg tctgtcaaca
     4801 aaggctagca gtcaagaaga ggcgaatcaa gcgctggata tcttggaaaa tcaaatcttg
     4861 gactgccaga ctttcgaagg aatttcttta cgagactttt gctatggtta tggggaagaa
     4921 actagtttag ccagcattgt ggtagaagaa ctgaaaaggc aagggaaaac catcgcggct
     4981 gcagagagtt tgacggcagg tcttttccaa gctaccgtgg cgaatttttc tggagtttca
     5041 agtatattta agggtggttt tgtgacctat agcttggagg aaaaatcaag gatgttggat
     5101 attcctgcca agaatttgga agaacatggt gtggtgtctg aatttacagc tcagaagatg
     5161 gctgagcagg cacgaagcaa gacccagtct gattttggaa ttagtttgac tggagtggca
     5221 ggaccagata gcctagaagg acacccagtt gggacagtct tcataggctt ggcgcaagat
     5281 caaggaactg aagttatcaa ggttaatatt ggaggcagaa gccgagcaga tgtacgtcac
     5341 attgcggtta tgcatgcctt taacctagtt cgcaaggctt tattaagtga ctaacttttg
     5401 atataatagt agataggtct gaggatcatt agaatgtagg agaatagaat ggcgaaaaaa
     5461 ccaaaaaaat tagaagaaat ttcaaaaaaa tttggggcag aacgtgaaaa ggccttgaat
     5521 gacgctctta aattgattga gaaagacttt ggtaaaggat caatcatgcg tttgggtgaa
     5581 cgtgcggagc aaaaggtgca agtgatgagc tcaggttctt tagctcttga cattgccctt
     5641 ggctcaggtg gttatcctaa gggacgtatc atcgaaatct atggcccaga gtcatctggt
     5701 aagacaacgg ttgcccttca tgcagttgca caagcgcaaa aagaaggtgg gattgctgcc
     5761 tttatcgatg cggaacatgc ccttgatcca gcttatgctg cggcccttgg tgtcaatatt
     5821 gacgaattgc tcttgtctca accagactca ggagagcaag gtcttgaaat tgcgggaaaa
     5881 ttgattgact caggtgcagt tgatcttgtc gtagtcgact cagttgctgc ccttgttcct
     5941 cgtgcggaaa ttgatggaga tatcggagat agccatgttg gtttgcaggc tcgtatgatg
     6001 agccaggcca tgcgtaaact tggcgcctct atcaataaaa ccaaaacaat tgccattttt
     6061 atcaaccaat tgcgtgaaaa agttggagtg atgtttggaa atccagaaac aacaccgggc
     6121 ggacgtgctt tgaaattcta tgcttcagtc cgcttggatg ttcgtggtaa tacacaaatt
     6181 aagggaactg gtgaccaaaa agaaaccaat gtcggtaaag aaactaagat taaggttgta
     6241 aaaaataagg tagctccacc gtttaaggaa gccgtagttg aaattatgta cggagaagga
     6301 atttctaaga ctggtgagct tttgaagatt gcaagcgatt tggatattat caaaaaagca
     6361 ggggcttggt attcttacaa agatgaaaaa attgggcaag gttctgagaa tgctaagaaa
     6421 tacttggcag agcacccaga aatctttgat gaaattgata agcaagtccg ttctaaattt
     6481 ggcttgattg atggagaaga agtttcagaa caagatactg aaaacaaaaa agatgagcca
     6541 aagaaagaag aagcagtgaa tgaagaagtt acgcttgact taggcgatga acttgaaatc
     6601 gaaattgaag aataagctgt taaagcagtg gaaaaatccg ctactttttc gatttttgat
     6661 tcaagttttt agattatata tagtagcttg aaataagata tgaacaactt tattaggaaa
     6721 gtcaaattaa tttctagaaa tgttttagca gctacagcgt actattccaa actcaaccaa
     6781 ctataataga tcgaaactag aatagtacac atctacttct aaaacattgt taaaaatcga
     6841 tttgactgtc cttatttcat tccgctatat ataagtttgc tgtttcttgt cgctcctctg
     6901 gaaagctgat ataatagctt tatgaataaa aaacgaacag tggacctgat acatggttcg
     6961 attcttccct cgctcttaag cttcaccttt ccaatcttgc tatcaaatat ttttcaacag
     7021 ctctataaca ctgctgatgt cttgattgtt ggacgatttc ttggtcaaga atccttggct
     7081 gcagtaggag cgacgacagc gatttttgac ctgattgtag gttttacact tggtgttggc
     7141 aatggcatgg ggattgtcat tgctcgttat tatggggctc ggaatttcac taaaatcaag
     7201 gaagcagtag cagccacctg gattttaggt gctcttttga gcattctagt tatgttgctg
     7261 ggctttcttg gcttgtatcc tctcttgcaa tacttagata ctcctgcaga aattcttcct
     7321 caatcttatc aatatatttc tatgattgtg acctgtgtag gtgtcagctt tgcttataat
     7381 ctttttgcag gcttgttgcg gtctattggt gacagtctag cagccctggg atttctgatt
     7441 ttctctgcct tggttaatgt ggttctggat ctctatttta ttacgcaatt gcatctggga
     7501 gttcaatccg caggacttgc taccattatt tcgcaaggtt tatcagcggt tctctgcttt
     7561 tattatattc gtaaaagtgt gccagaactc ttgccacggt ttaaacattt caaatgggac
     7621 aaaagcttgt acgcggatct cttggagcaa ggtttggcta tgggcttgat gagttcaatt
     7681 gtatctatcg gcagtgtgat tttacagttt tctgttaata catttggtgc agtgattatt
     7741 agtgcccaga cggcagctcg acgcattatg acctttgccc ttcttcctat gaccgctatt
     7801 tctgcatcaa tgacgacctt tgcttctcag aatctaggag ctaagcgacc tgaccgcatt
     7861 gttcaaggtc ttcgaatcgg cagtcgttta agtatatcct gggcagtttt tgtttgtatt
     7921 ttcctctttt ttgccagtcc agccttggtt tccttcttgg ctagttcgac agatggttac
     7981 ttgatagaaa atggaagtct ctatctgcaa atcagttcag ccttttatcc cattttgagc
     8041 ctcttgttga tttatcgcaa ttgcttgcag ggcttggggc agaagatcct tcctctagtt
     8101 tctagcttta ttgaactaat cggaaaaatc gtttttgtgg ttttgattat tccttgggca
     8161 ggatataagg gtgttatcct ttgtgaacct cttatctggg ttgccatgac agttcaactg
     8221 tacttctcac tattccgtca tcccttgata aaagaaggaa aggcaatttt ggcaaccaaa
     8281 gtgcaatcct agttggattt actgaataaa attcatttcc tctagtgaac atcgaaaaaa
     8341 cttgtgttct cgtctttagt ttggtgttga aaatagttta acagactttt gacttctttt
     8401 atatgatata ataaagtata gtatttatga aaaggacata tagagactgt aaaaatatac
     8461 ttttgaaaag ctttttagtc tggggtgtta ttgtagatag aatgcagacc ttgtcagtcc
     8521 tatttacagt gtcaaaatag tgcgttttga ggttctatct acaagcctaa tcgtgactaa
     8581 gattgtcttc tttgtaaggt agaaataaag gagtttctgg ttctggattg taaaaaatga
     8641 gttgttttaa ttgataagga gtagaatatg gaaattaatg tgagtaaatt aagaacagat
     8701 ttgcctcaag tcggcgtgca accatatagg caagtacacg cacactcaac tgggaatccg
     8761 cattcaaccg tacagaatga agcggattat cactggcgga aagacccaga attaggtttt
     8821 ttctcgcaca ttgttgggaa cggttgcatc atgcaggtag gacctgttga taatggtgcc
     8881 tgggacgttg ggggcggttg gaatgctgag acctatgcag cggttgaact gattgaaagc
     8941 cattcaacca aagaagagtt catgacggac taccgccttt atatcgaact cttacgcaat
     9001 ctagcagatg aagcaggttt gccgaaaacg cttgatacag ggagtttagc tggaattaaa
     9061 acgcacgagt attgcacgaa taaccaacca aacaaccact cagaccacgt tgacccttat
     9121 ccatatcttg ctaaatgggg cattagccgt gagcagttta agcatgatat tgagaacggc
     9181 ttgacgattg aaacaggctg gcagaagaat gacactggct actggtacgt acattcagac
     9241 ggctcttatc caaaagacaa gtttgagaaa atcaatggca cttggtacta ctttgacagt
     9301 tcaggctata tgcttgcaga ccgctggagg aagcacacag acggcaactg gtactggttc
     9361 gacaactcag gcgaaatggc tacaggctgg aagaaaattg ctgataagtg gtactatttc
     9421 aacgaagaag gtgccatgaa gacaggctgg gtcaagtaca aggacacttg gtactactta
     9481 gacgctaaag aaggcgccat ggtatcaaat gcctttatcc agtcagcgga cggaacaggc
     9541 tggtactacc tcaaaccaga cggaacactg gcagacaagc cagaattcac agtagagcca
     9601 gatggcttga ttacagtaaa ataataatgg aatgtctttc aaatcagaac agcgcatatt
     9661 attaggtctt gaaaaagctt aatagtatgc gtttttttgt ggagatattt ccttcaatgt
     9721 ttgctactat attaaacaaa aatcagaaag caaactagaa agttatgctc aaataaaatc
     9781 taaatttgac aatgtaaacc gagtcggata gctttaagta ctgttttgag gttgaagata
     9841 cgatttttga taggaactca tcaattttag atttttaagc aacatcaata aattgcttcc
     9901 ttgttttgtc ataatttttt tatttaaaaa attatgacaa gagtgtgcta ttctttttat
     9961 gagaggtgta tgaatatgat aaatgtatgt gataaatgta tgtgatgttg gaaaaagaat
    10021 aaaagaactt agaatatctt caaatcttac tcaagataag attgctgagt atttgtcttt
    10081 gaatcaaagc atgattgcca aaatggaaaa aggtgaaagg aatatcacga atggatttaa
    10141 gtaataaagc tccaaatctt agaaaaaagt tgggagctga tggtgaatcg ccgatagata
    10201 tttttaaatt ggtacaaaag atagaaaatt tgacgctggt attttatgga ctcggaaaga
    10261 atattagcgg agtctgttat aaaggaactc agttcagtct cattgcagtc aattcagaca
    10321 tgtcattagg aaggtaaaga ttttctttag cacatgaact gtatcatctt tattatgatg
    10381 aggtgaagaa gagttcagtc agtcttatct tgattggtga aggagatgaa actgaaagaa
    10441 aagcggatca gtttgcttct tattttttaa ttttcccatc ttcactgtat aggatggttg
    10501 aggaaattag agaaaatgcc aatagaactc atcttgaagt agaagatatt ataaaattgg
    10561 gtcagtttta tggtatcagt cataaagcta tgttatatag attgaggaat gatggatacc
    10621 ttgatgcaga agaaattaaa aatatggata ttagtgttat agagacagct tcaagattag
    10681 gctatgatac aagtttatat cgtcctttgt cagaaagtaa aaaggaaacg gtattaggat
    10741 aatatattaa ttcaactgaa caacttttag aaaataacag aatttcgcaa gggaagtatg
    10801 aggaactgtt actagatgct ttcagatatg atattgtata tgggctatat gaagaggggg
    10861 gagttgtcgt ttgactagtc gtgtatttat tgatgcagat tgtatttcag tatttttatg
    10921 ggttggcact gaacatcttt tagaaaagct ctatttgggt aaaattgtta ttccacaaga
    10981 ggtgtatgat gaaatcaata tacctacaat tccccattta aaatctagga tagaccagtt
    11041 ggtagctaag ggttcagctg agattgtgag catagacatt ggaactgaag aatacgcatt
    11101 atatagagat ttaacaagaa atcatgatag taacaagatt attggtaagg gagaaggggc
    11161 atctatttcc ttagcgaaaa agcataatgg gatattagga agtaataacc taagagatgt
    11221 taaatcatat gtagaagaat tttctttaga atatatgaca acaggagata tactgattga
    11281 agcgtttaaa gcgtaattta ttactgaata agagggcaat catatctgga ataatatgct
    11341 taaaaagaga aggaaaattg gtgcaaattc attttcagac tatcttcgtg gaagtattca
    11401 tcaaaataga caaaaataaa tttggataaa tcgaactcac tattcaggag gcatatgagc
    11461 aattcgaaaa agaaaagtgt caaattgagc ctataggagt agaagtgaaa tagtaagtcc
    11521 tgcatagtgg atgagagaaa agttctcctt gaagttttcc taaactatca gtcgcatgtc
    11581 aaacgatatg tagggtaatg tgagagggga tagcgagtag tttttggtta ttttatcaaa
    11641 aaacttatat tttattatac cgaatgataa aatataataa aaatgataga ataaggaaaa
    11701 aacatgaatg tcaaaaagat aatgtcaatt tttcaatcct tttatgttga tgtcagtatt
    11761 gaggaactga ctttgacttt accaatcagt tttgtaaaaa ggtttgagta tactcaaatg
    11821 acttttcata aggaatcatt tttattgatt aaagaaaaga gaagggggag tttgagttca
    11881 tttgttactc aggctcgcac tatgggtgaa aaagccaata tggatgttgt tttggtgttt
    11941 tcgaagttat cagacagtga aaaaaagcaa ttacttcaag ctagagttcc gtttgtagac
    12001 tttaagggaa acctcttctt ccctccattg ggactagtac tcaatgcgaa tgatactgaa
    12061 gtccctaagg aattaacacc tagcgaacaa ttaacgtgga ttgccttttt attgacaaaa
    12121 ggtcaaaaag tagtagatgt tgatttgctt tcacaagtca ctggacttcc aaattcaaca
    12181 atttataggt gtttgaggac ttttaaagcc ttatattggt taaacaagca aaataagctt
    12241 tacacatata cggtgtcaaa gaaagaatta ttcttaaaat ccgtgtcatg tttatttaat
    12301 cccatcaaaa aacggatttt attgccagat ggcgatataa agcagataaa atctgtttct
    12361 aaccttctat atggtggtgc ttatgctttg tcgcattcaa cttttttagc tgaaacggat
    12421 gaaaatatta gctatgtcat atggcagaga aaattcaatc agttatcctt gccactttct
    12481 cagcatgttt taaaatgaaa gatgctagag atatggaaat atcgtccttt tgtatctgag
    12541 ttttggaatg attttaaaaa taatcatgat aaacaatttg tagatccgat ttctctttat
    12601 ttgaccttaa aagatgatga tgacccacgt atagaggaag agagtgaagc actagaaaat
    12661 atgatattac agtatctggg agaagatgat gccagctaat acgaaagtta tttttcaaga
    12721 aatgtttgcg gattttcaga actattatgt tctgattggg ggaactgcta cctttatcgt
    12781 attggattcg caaggattta aaagtcgcac aacaaaagat tatgatatgg tcatcattga
    12841 tgaagtaaaa aataaggaat tttatactac cttgaatcat tttttagaat tgggagagta
    12901 tcaaggaagt cagaaagatg agaaagcgca gctttttcga tttacaacaa ctaattctga
    12961 gtttccttct atgattgaac tatttagtat cttaccagaa tatccattaa agaaggacgg
    13021 tcgagaaatt cccttatatt ttgaccaaga tgctagttta tcagccttat tattggatga
    13081 agattattat aatatattgg tgcatgtaaa agaaaccatt caggggtatt cggtattgag
    13141 taattgtggt ctatactctt cgaaaatctc ttcaaaccac gtcagcttcc atctacaacc
    13201 tcaaaacagt gttttgagca gcctgcagct agctccctag tttgctcttt gattttcatt
    13261 gagtattaat tatttttaag gctaaagctt ggctggatat gagggagcgc tctgccacag
    13321 gtgctcaagg tttaagtaag tccattaaaa agcatttgaa tgacattacc cgtttgacag
    13381 cttccttgct aggagatgaa aagttatcgg ctataacatc aagtagtgcg gtaaaagcag
    13441 acatgcaccg ctttgtgata gaattagagc ctgtgaagtc aactattctt caaaataatg
    13501 acatttcatt ggatcaaaat gaaatttttg aaattctgaa aaattttctc gatggttaaa
    13561 ataattgtag cgagatggct atattgaatt cgtctatatc tggaaactag aaaaaacttc
    13621 aatttcagga gaaaatgaag tcaatcttcc cacaatcaaa cgtatagtat caaggttttt
    13681 caagacctga tattatgcgt tttttgcttt tcaaaacttt ttgcccagtc ttcgttttta
    13741 tcctctagtc acttgatttg tttcaggtgg ttttttagta tggtagaatg aaacgagaac
    13801 aggacaaatt gatcaggaca gttaaatcga tttctaacaa tgttttagaa gcagaagtgt
    13861 actattctag tttcaatcta ctatagttaa atctgcggtc aagtctactg gtgaatctat
    13921 gattgtaata ctcttccaaa atctcatcaa ccacgtcagt cttgccttgc agcctgtatc
    13981 ttactgacca agctagtgat ggacttagaa taggtgattt ggagcgtcct attggctagg
    14041 aaatgctgat catagtcctt tgctgaggct agggtgtttc aacattcaac actcaactgg
    14101 ttgatctagt tgataggaag ggaattacta taaaatactc aggcttccat catatttttt
    14161 gaaacgattg tgtaatcaaa atgtaccaat attgtagtat tagtacagaa gatgttgtga
    14221 atggataaat atatcataac tgctgtctca aaaagatttc atatgtctgt gcatatataa
    14281 tagacttcct gcaaaactag aatcctagtt catgattgat aataccagca atcaaattca
    14341 ttcgtaatcc aaagcgttta cgatgatttc gataggttgt tgaaaacatt ttaaacgttt
    14401 ctactttggc aaagatgttc tcaaccttgc ttctctcctt ggatagcgca tggttacagg
    14461 ctttatcttc agctgttagc ggcttgagtt tgctggattt acgtggagtt tgtgcttgag
    14521 gatatatctt catgagccct tgataaccac tgtcagtcaa gattttacca gcttgtccga
    14581 tatttctgcg actcattttg aacaacttca tatcatgaca atagttcaca gtgatatcca
    14641 aagaaacaat tctcccttga cttgtgacaa tcgcttgagc cttcataacg tgaaatttct
    14701 ttttaccaga atcattcgct aattgttttt tagggcgatt gatttttact tccgtcgcat
    14761 caatcattac cgtgtcctca gagctgagag gagttcttga aatcgtaaca ccactttgaa
    14821 caagagttac ttcaacccat tggctccgac ggattaagtt gctttcgtga acaccaaaat
    14881 cagccgcaat ttcttcataa gttcgatatt ctcgcacata ttgaagagtg gccataagaa
    14941 ggtcttctag gcttaattta ggtt
//
LOCUS       DAVLGK010000047        14729 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLGK010000047 DAVLGK010000000
VERSION     DAVLGK010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14729
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.048"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..701
                     /locus_tag="VXE01_001767"
     CDS             <1..701
                     /locus_tag="VXE01_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0750629.1"
                     /translation="LLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCL
                     DIIFPELDKIVGKHSEYTYQLLTRYPNPQKRLEAGFDKLIEIKRLTASKIQDILSVAP
                     RSIGTTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVIL
                     AEIRNIHSFDNPAQLQAFAGLDSSIYQSGQIDLAGRMVKRGSPHLRWALIQAAKACAR
                     FSPAFKAYLKTKLE"
     gene            complement(1002..2891)
                     /locus_tag="VXE01_001768"
     CDS             complement(1002..2891)
                     /locus_tag="VXE01_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV0750630.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            3029..4594
                     /locus_tag="VXE01_001769"
     CDS             3029..4594
                     /locus_tag="VXE01_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0750631.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4594..5334
                     /locus_tag="VXE01_001770"
     CDS             4594..5334
                     /locus_tag="VXE01_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0750632.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(5443..5658)
                     /locus_tag="VXE01_001771"
     CDS             complement(5443..5658)
                     /locus_tag="VXE01_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750633.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(6542..7792)
                     /gene="ilvA"
                     /locus_tag="VXE01_001772"
     CDS             complement(6542..7792)
                     /gene="ilvA"
                     /locus_tag="VXE01_001772"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV0750634.1"
                     /translation="MLSSKDIIKAHKILNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7842..8198)
                     /locus_tag="VXE01_001773"
     CDS             complement(7842..8198)
                     /locus_tag="VXE01_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0750635.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(8436..8672)
                     /locus_tag="VXE01_001774"
     CDS             complement(8436..8672)
                     /locus_tag="VXE01_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750636.1"
                     /translation="MLADQNKADWSYDENTVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSSFERAGATKSARYIAKWILRNKKH"
     gene            complement(8779..9801)
                     /gene="ilvC"
                     /locus_tag="VXE01_001775"
     CDS             complement(8779..9801)
                     /gene="ilvC"
                     /locus_tag="VXE01_001775"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0750637.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVTEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9867..10343)
                     /gene="ilvN"
                     /locus_tag="VXE01_001776"
     CDS             complement(9867..10343)
                     /gene="ilvN"
                     /locus_tag="VXE01_001776"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV0750638.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(10336..12036)
                     /locus_tag="VXE01_001777"
     CDS             complement(10336..12036)
                     /locus_tag="VXE01_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV0750639.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(12237..13904)
                     /locus_tag="VXE01_001778"
     CDS             complement(12237..13904)
                     /locus_tag="VXE01_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV0750640.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13907..14272)
                     /locus_tag="VXE01_001779"
     CDS             complement(13907..14272)
                     /locus_tag="VXE01_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0750641.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(14429..14617)
                     /locus_tag="VXE01_001780"
     CDS             complement(14429..14617)
                     /locus_tag="VXE01_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV0750642.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
BASE COUNT         4371 a         3328 c         2568 g         4462 t
ORIGIN      
        1 aacttctttc tgaccccaat cgtgaacaat ttcaacacga taatcggcaa gtagaactaa
       61 aaatactggc tagacatatt catcgtctca agaaaaaaca gtctgattgg aaagtacaat
      121 acactcgttg tcttgatatc atctttcctg agttggataa aatcgttgga aagcattcag
      181 aatataccta ccaactcttg acacgctacc ctaatcctca gaaaaggctt gaggcaggat
      241 ttgataagct gatagaaatt aagcgattga ccgcttctaa aattcaggat atcctctcag
      301 tcgcacctcg ttctatcgga acaacatctc ctgctcgtga attcgaaatc atcgaaatca
      361 tcaaacatta caagaggctc attgacaagg cggaaacatg tgtcaatgac ttgatggctg
      421 agttcaactc ggtcatcacg acggttactg ggattggggg tcgtttaggg gcggtcattt
      481 tagccgagat tcgaaatatt cattcctttg ataatcctgc tcaattacaa gctttcgctg
      541 gactggattc ttctatttat cagtcaggtc agattgattt agctggaaga atggtcaaac
      601 ggggttcccc tcatctgcgg tgggcactca tacaagctgc caaagcatgc gctcgctttt
      661 cacctgcttt taaggcctat cttaagacta agttagaata aggaaaacat tacaatgtag
      721 ccatcatcca ccttgcaaaa aaacttatcc gaaccctgtt ttatatccta aaaaagagct
      781 gccatttgac gaacaaaaag tgatgtaatt tctgaaatta acacaggatt acctttgaaa
      841 aaatggactt tttcaagggc tttttgccgt gctctaaaat catcgccaaa tcatcaaatt
      901 gaaataagaa atagtttaga taaaactatt gacttttctt atagtttgtc tttcttctat
      961 cttccattat atcatacttt ttcagtctat ggtagctctc tttaaaaggc tccgatactg
     1021 ccgccacctc cgcctccaga gaagccaccg ccagaacttc cacttccaga agatacggag
     1081 taggtacttg ctgtatttgc gacactagca taatggctca tttgcgcgct tgaatgataa
     1141 aacatactgt gccagccata agctacatag agattgatat ctggattttc aacttgaatc
     1201 tgatgaacct tcatcaaatg actaaccttg tccgcatagc caaataaggt tgcatagacc
     1261 aagagacgat tccaaacaac aatactttcc aattcagcct tatccagtcg tgcaatctca
     1321 cgtaacatat tttcaaaact ggtccagaga tagtagacct cagctcccgc ttcatttaga
     1381 acaccatcac gattatctag tcgaagcttc caataataga aaacagacaa aactaaccct
     1441 agaaaaccaa gtattggcaa agggaggtaa agatagccat gaacgtctaa actgtacaag
     1501 aacaaaccaa atccgataaa taggggcaag atagtcaaga cacccatacc cacttgcaaa
     1561 gccttttcca aaccagttaa aggacgatag taatctggga gcccccagaa ggaaactcgt
     1621 tttctcactc cttcttgcat ctggttcaat acctcttcaa aagaagattt gagttgaagc
     1681 cctcttgctt gaatccgttt ttcatcagaa actttggctc tacgataaag actatcagat
     1741 accttgtaat ccgcaaacaa attggaaaga gtttcttctt ttttacctga aaaagctaga
     1801 tttaggcagt ctttctcaaa gcttgacaaa ccatcttctt ttactagcct caaaccaact
     1861 gcatctcctt ctgaaatgat agagacattc ccacggtcta tcacatctag caaggtagct
     1921 tgaataagtt gatcaaaggt gaattttcca gctcccttga ccaagggact cacttcctcc
     1981 aaggaggtcg agtagactgc ttctgataaa accataggct ctaattccat tgggggttca
     2041 tagagacgat gatttttggc atatttgact gaaggagtgg tctttcttct ataaataaaa
     2101 tagaagcaga cactcaataa caaggagatg gaaaggatcg aagggaagat ccaagtaagt
     2161 agttgtttac tttgctcttt ttctttaacg atcgaatcct ctatcttatt aaactcttct
     2221 aaacgattcc ctttcaatcc ctgatcccta gcgctagcaa aatcggtccg aggccaatag
     2281 gcatgcaact caactccacg cttagccgga agattgtcta aacggatagt ataatcaagg
     2341 ttactctttt caatcgttcc ctctctaaaa agtttccctg tatggaaaaa gagtttttca
     2401 gcccccttgt ctccccttac atgaaattca aacttttcaa tagactctga actatctgtc
     2461 agaggttgcc aatttaattc agcgatatca tcataaagga aaagtaaatt ttttaagttc
     2521 cagacgaggt caacttcaac tatgtcgccc tcctgacctg gattatagac tctcacagta
     2581 taaccatccg cttcttctgt tacttcgcta gtcacatctg ctagttctgc accgtttttc
     2641 gcggcctgaa cctttggatg agggtcaatg tcaaacccgc taggcatctt accagcacgt
     2701 ccaagtccca cgatttgtcc cttaaagtcc tcctcaaact ggtaaactat cttctgtcta
     2761 aactctgccg tattatctgc atgaatatac aaatcccctt gataagagtt tatcttgaaa
     2821 tcaatggcaa aaacagagag tggaagaagg caaaacaagc ctaacaccag taagaaaaaa
     2881 gtttttttca tcaactaagc ccccttttta tctttcttat cattatagca ttttttcgta
     2941 agtaaaggct tacttatgtt gaaaaattac gcatttttcg ataaaatagg agacagttat
     3001 tttttaatag atcagaatag gagaaatcat gagaaaaata tacttatcta ttttcacaag
     3061 tctcttgctg atgctaggac ttgtcaatgt tgctcaagcc gatgaatatt tacgcatcgg
     3121 gatggaagca gcatatgctc cctttaactg gacccaggat gatgatagca acggagctgt
     3181 caaaatcgat gggaccaatc agtatgccaa cggatacgat gttcaaatcg ccaagaaaat
     3241 cgctaaggac ttaggtaaag aacctttggt tgttaaaacc aagtgggaag gtctagtccc
     3301 tgcccttact tctggtaaga ttgacatgat tatcgcaggt atgagtccaa ctgcagaacg
     3361 caaacaagaa attgcctttt cgagcagtta ctacactagc gaaccagttt tgcttgtcaa
     3421 aaaagattct gcctacgcaa gtgctaaatc tttggatgac tttaacggtg caaaaatcac
     3481 ttctcaacaa ggggtctacc tctacgactt gattgcacaa atcccaggtg ctaaaaaaga
     3541 aacagccatg ggagacttcg ctcaaatgcg acaagctctt gaggctggtg tcattgatgc
     3601 ttatgtttct gaacgtccag aagcactgac tgctgaagct gcgaactcta agttcaagat
     3661 gattcaagta gaacctggtt tcaaaactgg ggaagaagat acagctatcg ctatcgggct
     3721 tcgtaaaaat gacaatcgta ttagccaaat caatgccagc attgaaacca tttcaaagga
     3781 cgaccaagtt gccctgatgg atcgtatgat caaggaacaa cctgccgaag ctacaacaac
     3841 tgaagagact agcagtagtt tctttagcca agtcgctaaa attctttctg aaaactggca
     3901 acaactcttg cgtggtgctg gtatcactct tttaatctct atcgtcggaa ccatcatagg
     3961 tctcattatt ggacttgcca ttggtgtctt ccgtactgct cctctctctg aaaacaaagc
     4021 catttatggc cttcaaaaac tagtcggctg ggttctcaat gtctacattg aaattttccg
     4081 tggtacgcca atgattgttc aatcgatggt tatctactat ggaactgccc aagctttcgg
     4141 gatcaacctt gaccgtacac tggctgctat cttcatcgtt tcaatcaata ccggtgccta
     4201 catgactgaa atcgtccgtg gtggtatcct agcagttgac aagggacaat ttgaagctgc
     4261 gactgctctt ggtatgaccc ataaccagac catgcgtaag attgtcctac ctcaggtagt
     4321 ccgtaacatc ctacctgcaa ctggtaatga atttgtcatc aatatcaaag atacatctgt
     4381 attgaacgtt atctctgttg tcgaacttta tttctcagga aataccgtgg caacacaaac
     4441 ctatcaatac ttccagacat ttacaatcat cgccgtgatt tactttgtcc tcaccttcac
     4501 cgtaacacgt atcctacgct ttatcgagcg cagaatggac atggatacct acactacagg
     4561 tgctaaccaa atgcaaacgg aggatttgaa ataatgacac aagcaatcct tgaaattaaa
     4621 cacctcaaaa aatcctatgg acaaaacgaa gtgctaaaag acatttctct cactgtccac
     4681 aagggagaag ttatttctat catcggaagc tctggaagtg ggaaatcaac cttcctacgc
     4741 tccattaacc tacttgaaac gccaactgat ggacaaatcc tttatcatgg acaaaacgtc
     4801 ctcgaaaaag gctatgacct cacgcaatac cgtgaaaagt tagggatggt tttccaatcc
     4861 tttaacctct ttgaaaatct caacgttctt gaaaacacaa tcgtcgctca gacaactgtc
     4921 cttaaacgcg aacgcacaga agctgaagaa attgccaaag aaaacctgga aaaggtcggc
     4981 atgggagaac gctactggca agctaaaccc aaacaactct caggtggtca aaaacaacgt
     5041 gtggccattg ctcgtgccct ttcaatgaat cctgacgcca ttctctttga tgaaccaaca
     5101 tcagctctcg atccagaaat ggttggagag gtcctcaaaa tcatgcaaga tctggctcag
     5161 gaaggcttga ccatgattgt cgtaacccat gaaatggaat ttgcccgtga tgtctctcac
     5221 cgtgttatct ttatggataa gggcgtgatc gctgaagaag gtaaaccaga agacctcttc
     5281 accaatccta aagaagaccg aacaaaagag ttccttcaac gctatctcaa ataaaaagaa
     5341 aaggctgcat caaccgtgca gtctttttgc tgtcctcaaa atgaaaaggc agattctcta
     5401 tctctactac ttgaaggtca agaatccgcc gttatccaaa gattaatctt caaatttttc
     5461 atgatttttt tcatagaaat caattaggcc tagggctgtt tcaaatgaaa tattttttac
     5521 ttttgcacga ccctgcgcca gagcaatgat agacatttca cgcgcattcg tttctttaga
     5581 gatacggtag cctgtgattt tcttatcacg aacccagcca acaactgatt ctactttttc
     5641 aaagtttgac ttagccatgt ttttctccta ttttcttctt tataatattt aattgtatac
     5701 gtttttacta cttttgtcaa taaaaaaaca tgtattcaac gaaaataatt agttcagaat
     5761 tttagcttca gaattttctt acttcctttt tgaatccgat aatatatagg ttttactagt
     5821 ctctacacca taaatatttg ctaataaaaa tactgtatta ttaccctctt aaggtgcgaa
     5881 attattcaag ttcttaaaaa atgcttctct atttccgtaa gatagcttat ttcttcgatt
     5941 taagaactga agatgatagt tctaaccttt agaaatccaa gccttcacta gctcaaaaac
     6001 tcctatcttt cttcctcaat aaatcatctg agagataggt attccttata tccttcaaat
     6061 tcatcactcc tttggatatt gaggtgctag cctagaagca gacacccgat tatctaaacc
     6121 atccttaata gagatgacaa gacagataag ctcagttaat tacttatata tctttttaat
     6181 atggtatatt tgtcaacaaa aagaaatcaa atcatacctt atactcaatg aaaatcaaag
     6241 agcaaactag gaagctagcc gcaagttgct caaaacactg ttttgaggtt gcagatagag
     6301 ctaacgtggt ttgaagagat tttcgaagag tattaaagac agtgtgacta tgcttgtcaa
     6361 tagataggaa atcaaaatga aggatggaaa tctgagccaa acatcataag tgctataatg
     6421 aacagaagta agaattgcac gataagtttc ctaaaaccat agaaatcgtc ccctttcttc
     6481 atcttcatta tagcacatat acatcagttg tacaaataat atgatatttt tttattagtc
     6541 ctcagacaag catattataa agcgtttcat taccatttaa gttaatataa gctggatcaa
     6601 aaccttccat tctacgaatc aaacctgcat aatcatgctt atctgctaaa gcgatcccaa
     6661 ttaatactgg gcctgttccc ttgctagctc gtttgatata ctcaaaacgt gtgatatcat
     6721 catttggccc caggatatca tttacaaact cacgcaaagc tcctggacgt tgtgggaaat
     6781 tgaccacaaa gtaatgtttg ataccatcat aaatcaaggc acgctcttcc atttctggca
     6841 tacggttgat atcattattt cctccagaaa tgatacaaca aatggttttc cccttaatat
     6901 attcagctaa aacctctaaa gaggcgatac tagccgctcc agcaggttct gcgactatcc
     6961 cttgcttaga gtaaaggtca atcaaggttt cagaaatcaa tccctcatcg acacctacca
     7021 aagttttaat atgttgacga gttgcttcat aggtcaactg acctaccttt tgcacagcaa
     7081 tcccatccgc aaatttatca atttccttga gtttgactgg acctccagcc tcaaaggcag
     7141 ctttcatgga acgcgctcca ttcgcctcta ctccgataac ctcaatctct ggacttgttt
     7201 ccttgatata ggtagaaacc ccggcaatga gaccgccacc accaacagga accaagacag
     7261 catcaaaatc aatcgattct tttcgagctt cttctaaaat ctcataagca actgttcctt
     7321 gacctgcttg aacatgagca tcatcaaaag gatcaataaa ggtacgattt tcagagactg
     7381 taaattcttg agctgctttg gctgaggcat caaaggtatc tccaactagt ttaatagtta
     7441 caaaatcccc accaaaaaag cgaacctgac caatcttttg ttgtggcgta gtaataggca
     7501 taaagatagt agcaggaatt ttcatttcat tacaagtata ggctactccc tgcgcatgat
     7561 ttcccgcaga agcgcagact accccacgtt cacgttcttc cttgctgagc tgggaaatgg
     7621 cataataggc accacgaatt ttaaaggagc gaacacgctg ggcattttct tttttcaaat
     7681 aaatcttagc accatacttc tccgataaat aatgatcgta atccagtgga gtattcacaa
     7741 ccacaccgtt caagatcttg tgagccttga ttatatcttt tgaacttaac atataaaacc
     7801 tctttttcta taaaaaacag tcactaatga ctgtttttta gttattcatc tccgaaaact
     7861 tcagtaacac tttcatggta tttatgagcc atacgaatcg aaaactcttt aggaagctca
     7921 taacgatttg tggaaatcca atcatataac cattctacca aactttcttc actatcatta
     7981 cgatggaaga taaaatagtt taaaatttct ttatattcta catcattcaa atccaacgtg
     8041 tctacaaatt gactacgagg aacaaaatta gaatctaatt ttcttagttg atctgtcaat
     8101 tctcccaatt gtaaatccaa ctgaaaaaat agtttttgca gttgcctatc agtttcatca
     8161 catcctgtct tgatagaaaa caaattggta atattcatat gatttcaacc cctaaataag
     8221 tacatctaat atcccacgaa tagctgaagc taaagttttc gcagtccagt catttaaacc
     8281 cgattctttc aatccagatg caataatttg ctctatttga tataaaccgc catctatcgt
     8341 ctcatttatt ctgcgaagag gaccttcaat ataggataaa gcttctccga atctaacagc
     8401 tgatttaggt cctaatgatt taccaactat atttgttaat gttttttatt tctcaaaatc
     8461 catttcgcta tataacgagc agatttagtc gcaccagctc tctcaaacga agaatgaatt
     8521 tcaagacctt cttctctagc tatttgtgcc aatttgaaga attgttcaaa ggtcatatgc
     8581 aacctaccat cttcaaaatt agcatcatca taaatgttaa ttacagtatt ttcatcatac
     8641 gaccaatctg ctttattttg gtctgctagc actattaccg acggtgtaat tacattatac
     8701 aactagaacc aataataacg atgcaatttt tctcataatc tttttcataa aatcatctcc
     8761 agcgctatat atttctaatt agttatagat tttgaatgca tcatcgtcgt ttttaccaac
     8821 gaatggcatt gctttacgca attctgcacc aactttttca atttcaaggt tagctgcttg
     8881 ttcacggtaa gcagtcaatt ttggacgtcc agctttatag tcatttacaa agtcatttgc
     8941 aaatttacca ttttggatgt ctgccaagac agccttcata ttttctttaa cttgttcagt
     9001 gattacacgt ggacctgata catagtcacc gtattcagca gtgtttgaaa tagattgacg
     9061 cattttcttg aatccacctt cgtagatcaa gtcaacgatc aatttcattt cgtgaagaac
     9121 ttcaaagtaa gccaattctg gagcgtaacc tgcttctgtc aagacttcga aacctgcttc
     9181 gataagggca gtcaaaccac cacaaagtac agcttgttca ccaaacaaat cttcttcagt
     9241 ttcttctttg taagttgttt caagaagacc tacacgagcc gctccaacac ctttacacca
     9301 gtccatagca atgtttttag catttcctgt tgcatcttgg tatactgcat aaagagctgg
     9361 aacaccaaat ccttcttcgt aagtacgacg taccaagtgt cctggtcctt taggagcaca
     9421 catgaagaca tctacatccg caggaacttt gataaattca aagtggatgt tgaaaccatg
     9481 ggcaaatcca actgcgtttc cagcttccaa gtttggagcg atttctgctt cgtacaattc
     9541 ttgttgaatt tcgtctggcg ccaagatcat gataacatca gccaacttag tagcttctgt
     9601 tactgtgtaa gtatcaaatc catcttcttt tgctttatca aaagatttac ctggacgtac
     9661 accgataata acgtcacgac ctgaatcacg caagttttga gcatgcgcat gcccttgtga
     9721 accataaccg ataacggcga tttttttacc gtcaagtgct gctactttaa catctttttc
     9781 atattccatt tgaactgtca tagcttttct ctcttttcta ttatttattg ccttttaagc
     9841 tggtttaaca aatttaagtt ggatttttaa tcgcgggtaa atccagttgc acccgttcga
     9901 gcaatattgc gaataccgta tgggcgaatg actcgcaata gggcttcgct cttttctgca
     9961 tttcccgtca tctgaatggt aatcgagctt ggcgctacgt ctaccactgt tgcacggaaa
    10021 ggttgaataa tcgctaaaat ctcagctctc ttctcagctg gcgctgacat cttaaccaaa
    10081 atcacctcgc gctccaaatg aggcttgtct gtaatatctc gaatgcgaat cacatcaatc
    10141 tgacgattga gctgtttgat gatttgctcc acttcatcat gagaagcaac atcaataata
    10201 atagtgatac gcgatacatt cggatcttct gttgctccaa cagagatgct ttcaatatta
    10261 acctgacgac gagataggac acctgtaaag cgattgagga ctcctgaacg attttgtagt
    10321 tttgctgtta acattctacg catggaactg cacccccaac atctcatgat tactcttacc
    10381 agccggtacc attggtaaca cctgttcctt acgagaaata tctacctcaa ttagcatagg
    10441 aacatcctca gtgatgactt caaggtcttg agccaaggtc tcaggattgt caaacttata
    10501 gtttttaata ccataagcct gcgccatcaa ttggaaatca ggaagggtat caaagaccga
    10561 ctctgatgtt ctgccttcat agaaggattc ctgccactgg cgaaccattc cgagtgaatg
    10621 attgttcagc ataaccacct tgattggcac cttgtaaata ttcaaaatag ccaactcctg
    10681 gttggtcatt tggaaaccac catccccaac aaacaagact acttccttat ctgggttagc
    10741 aattttagca ccgattgctg ctggaattcc aaagcccatt gttcccaaac cacctgaagt
    10801 cactaactga cgttcatttt ggtagggata atactgagct gtccacattt ggtgttgacc
    10861 aacgtctgtt accacaatgg catctccatt cgtcaattca ccaattcgtt caataactgc
    10921 ttgcggttga accacacgct ctttcttgtc ataagaacga acacgattct tgtctttagt
    10981 gactttctca atccactttt cagtattgtt gtgaactgtt ggttctgcta gcaacatttg
    11041 caaggccttc ttagcatctc caactacagg aatgtctgca ctgataatct tgccaatctc
    11101 agctgggtca atatcaatgt gggcaacctt agcattctta gcgaaagtct taggattccc
    11161 cgtcaaacgg tcatcgaaac gagaaccaat actaatcata aagtccgctt ccgtcatggc
    11221 aatatttgct gcgaatgacc cgtgcatgcc tcccattcca agaaagagtg ggtgactcgt
    11281 tgcaatcgtt ccttgtccca aaagactggt taccactgga atttgatagc gttctgcaaa
    11341 ttcatttagt tccgtagcag cctcagcata actaattcca ccaccagcta acaagactgg
    11401 ctttttagcc ttggacaatt gcttcaagat tttcttgatt tgcatatcat tcggctcaag
    11461 agtcggctga taacttggta aattcacttc tggtgaataa atgaagtctg tttctaaagc
    11521 agatatgtct tttggtaggt caattacaac tggccctgga cggcctgtag ttgcgatatg
    11581 gacagcttcc gtaatgatac gcggaatatc agctgtctca cgaacttggt aattgtactt
    11641 agtgattggc atggtaattc ccacgatgtc tgcctcctga aaggcatcct tcccaatccc
    11701 tgctcgcgcc acctgacctg taaagaccaa aaggggaacg ctatcgctca tagcatccgc
    11761 aatccctgta atggcatttg ttgctcctgg tccactagtg acgacggcaa cacccaactt
    11821 tccagttgat ttggcataac cttcagcttc atgcaaacaa ccttgctcat ggcgccctag
    11881 aatgtggcga atgcctttaa aattatatat cgcatcataa aaaggcaaaa ccgcaccacc
    11941 aggataacca aagatggtat caactcctaa atcacgaagt gtttccaaaa ctaggtccga
    12001 ccccgtctta ggagattcta aactgatttt ctccattgtt cccctttctt tcctcttaaa
    12061 aataacttgt tactatcata ccattttttc aaaatttttc aagataaaag aagaaatttt
    12121 ctgaattttc tattttaacg tttatttatg aatgttattt ttgtttttat taaaaagata
    12181 ccgatttcat ttactaaaaa agaaaaaaga actgatttct cagtccttca ttaatcttat
    12241 tccacactaa ataggtatgg gtaaacaggt tgttgacctt ggtgaatctc gacttcaacg
    12301 tcttcgaatt cttctacgat ttcttgagcg atttcattag caagttcttc gcttccgtct
    12361 tcaccgacat agaaggttac gatttcactg tcttcatcca acatatgttt caaggtttca
    12421 gtcaatgttt ggtgcatatc agggtttgac acaagaattt ttccatccac catacctaga
    12481 ttatcgtttt catggatttc taagccatcg atcgttgtat cacgcacggc tgttgtgacg
    12541 cttccgctaa caacatcgct aagagcagct gtcatacgct cttggttttc ttcaatggac
    12601 ttgcttggat caaaggcaag aagacttgtc ataccttgag gaagagtgcg agcctctacc
    12661 actactgctg gttgctccaa aacttctgcc gcagattgag ctgccatgaa gatgttcttg
    12721 ttgtttggca agaagatgat gttacgggca ttgacctgtt caacagcctt gataaagtct
    12781 tctgttgaag ggttcatggt ttgaccgcct tcgataacat aatccacgcc ttgagaacag
    12841 aagatatctg ctagaccttt accagccacc acagcaatca aagcatactc tttttcttca
    12901 gccgacttga taacttgagt agcttctttc tcaacctgtg cttcgtgttg gttacgcata
    12961 ttgtcaactt ttaccttgac caagctacca tatttgagac cttcttgcat aacaagtcct
    13021 ggatcttctg tatgaacatg gactttgaca atttcatcat cgttaacaac gaggagagaa
    13081 tccccaagct catccaagta gttacggaat tcatcgtagt caaaatcttt agcataggtt
    13141 ggaccttgct taagagctac catgatttca gtacagtaac caaacgtgat gtcctcagtc
    13201 gctacgtgac cagctacaga cttatgatgc tctacattga tcatctcact catgttggca
    13261 ggagtcgcta caaagtcctc agatgcaata tattcgccag taagggctga aaggaaacct
    13321 tcgtagatga agaccaatcc ttgaccacct gagtccacaa cgccaacttc tttcaatact
    13381 ggaagcatgt ctggtgtttt agctagagct gttttagcac cttccaaggc tgcgcgcatg
    13441 acttcaacag tatcatctgt ttgctcagct tttttcttag caccgatagc agctccacga
    13501 gaaactgtca aaatcgttcc ttcaacaggt ttcatcactg ccttataggc aacttccaca
    13561 cctgattgga aggccagagc caagtcttga cctgttaact cgtctttatc cttgatagct
    13621 tgggaaaatc cacggaaaag ctgagatgta atcactcctg agttcccacg cgcacccatc
    13681 aaaagccctt tggcaagaat gctcgctact tctccaactg tagaagctgg cttgtctgca
    13741 acttctttag caccattttc aatggtcatt cccatatttg tcccagtatc tccatctgga
    13801 actggaaaga cgtttaatga attgacatat tcagcttgct tattcaagcg agttgatgca
    13861 gcctgcacca tttcttgaaa taagctagta gtaatctttg acacggttat tctcctacaa
    13921 ctttgatatt ttgaatgtag acatttacag tctgagcagt aattccaagc tggttttcca
    13981 agctaaaggc aacacgctct tgaatgtttt ttgacacttc actaatcttt gttccgtagc
    14041 ttaacacggt atatacatca actgcaatac tgccatcttc ggctgccttt acgacgacac
    14101 ctttagaata attttcctta cctagcaggg cttggaaatt atctttgagg gcatttttac
    14161 tagccatacc gaccacacca aaaatctcag ttgctgctcc acctacgacg gttgcaatca
    14221 cttcatctgt tagttcgatt tgaccatctt ttgtattaat ttttacagtc atccttttta
    14281 cctcaactag ttgatactct attttatcat atttcagccc aagtgtaaaa gcagaatgat
    14341 gtatcagcgg atatttactc tatttttcaa acgatgttat acccacaata aaagaaaaaa
    14401 gaccctaagg tctcctttgc ttttattatt aaacgcgttc aactttacct gatttcaaag
    14461 cacgagctga agcccaaact tttttaggtt taccatcgat aagaacagta actttttgaa
    14521 ggtttggttt tacggcacgt tttgtttggt tcatcgcgtg tgaacggttg tttcctgata
    14581 cagtcttacg acctgtaaag taacatactt tagccattgt gttttcctcc tattagatct
    14641 aatatagcgg atgtgctagc accacatacc gtactatgtt atcacacttt cttgtttttt
    14701 gcaagggaat tggaagattt tttatttgt
//
LOCUS       DAVLGK010000048        14718 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLGK010000048 DAVLGK010000000
VERSION     DAVLGK010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14718
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.049"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            286..729
                     /locus_tag="VXE01_001781"
     CDS             286..729
                     /locus_tag="VXE01_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0750643.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            733..1497
                     /locus_tag="VXE01_001782"
     CDS             733..1497
                     /locus_tag="VXE01_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV0750644.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            1512..2240
                     /locus_tag="VXE01_001783"
     CDS             1512..2240
                     /locus_tag="VXE01_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750645.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            2233..3753
                     /locus_tag="VXE01_001784"
     CDS             2233..3753
                     /locus_tag="VXE01_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV0750646.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            4098..4904
                     /locus_tag="VXE01_001785"
     CDS             4098..4904
                     /locus_tag="VXE01_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV0750647.1"
                     /translation="MHTYLQKKIENIKATLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLPN"
     gene            complement(5070..5606)
                     /locus_tag="VXE01_001786"
     CDS             complement(5070..5606)
                     /locus_tag="VXE01_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0750648.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            5739..6629
                     /locus_tag="VXE01_001787"
     CDS             5739..6629
                     /locus_tag="VXE01_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV0750649.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            6873..7226
                     /locus_tag="VXE01_001788"
     CDS             6873..7226
                     /locus_tag="VXE01_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0750650.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            7227..8264
                     /locus_tag="VXE01_001789"
     CDS             7227..8264
                     /locus_tag="VXE01_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0750651.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(8310..9317)
                     /gene="galR"
                     /locus_tag="VXE01_001790"
     CDS             complement(8310..9317)
                     /gene="galR"
                     /locus_tag="VXE01_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV0750652.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVVEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            9481..10659
                     /locus_tag="VXE01_001791"
     CDS             9481..10659
                     /locus_tag="VXE01_001791"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV0750653.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYKVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            10678..12159
                     /locus_tag="VXE01_001792"
     CDS             10678..12159
                     /locus_tag="VXE01_001792"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0750654.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEETVRLETIEDSQTAREILGTELMDLVTPCPSQVNSDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDETPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            12229..12633
                     /locus_tag="VXE01_001793"
     CDS             12229..12633
                     /locus_tag="VXE01_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV0750655.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEDRQVRI"
     gene            12790..13644
                     /locus_tag="VXE01_001794"
     CDS             12790..13644
                     /locus_tag="VXE01_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEV0750656.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELIPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            13670..14440
                     /locus_tag="VXE01_001795"
     CDS             13670..14440
                     /locus_tag="VXE01_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0750657.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            14427..>14718
                     /locus_tag="VXE01_001796"
     CDS             14427..>14718
                     /locus_tag="VXE01_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0750658.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFS"
BASE COUNT         4341 a         2488 c         3470 g         4419 t
ORIGIN      
        1 taaaagaaca gatggaagca attatgattt acttctatct ttaaaataaa tggtctgata
       61 ggaaaaatgt gtcccctcat aaaatatagg atagtacgaa tggaaggctt ttgtagactg
      121 gaggacgaag gagtttagaa actctcgtta aaagttagtt gagccggagt atggtggtgt
      181 ggataattat caaaaattat ttctaaatcg aaatagttga cagttagaac gatgagtgtt
      241 acaattattt tattcatttc gatatcgaaa taaattggag gtgttatgaa agatggtcat
      301 ttgctagccc atcatattcg tttgttgaat gggcggattt ttcaaaagtt actgagtcaa
      361 gatcctgagg ctctttatag gggtgaacag ggcaagattt tagcggtttt atggaatagt
      421 gaaactggct gcgcaactgc gacagatatc gcgcttgcga ctggacttgc gaataatacg
      481 ctgacgacta tgataaaaaa gctagaggaa caaaagcttg taattgttag tccgtgtgga
      541 aaagacaagc gtaagaagta tttagtttta acggagttag gcaagtccca gaaagaagtg
      601 gggcatcgtg tcagtcagaa attggatact atcttttaca aaggattttc agaggaagaa
      661 attcaccaat ttgaaggttt tcaagaaaga attttggcga atctgaaaga gaagggaaat
      721 gaggtttaga atatgtcaca acaagtgaaa aatgctcaca acctatacat ccatgccatt
      781 caagacggac gagttgctga ggctcaagcc cagtctgtag gggataccta tatccaacat
      841 tcgacaggtg ttcctgacgg gaaagaagga tttgcagcct tctttgcaga tttctttgag
      901 cgtcatccag agcgtcagat taagattgtc cgcaccattg aggatggcaa tctggtcttt
      961 gttcatgttc atcaatatct gaatggtgga gaagctcaat gggtgacgac ggatactttc
     1021 cgtgcggatg agaatggtcg tattgttgag cattgggatg tcattgacta ctatcgaaca
     1081 cctgaaaatg accaactaga tcaaattttt ggagattttg aaatcaagga tttggacaag
     1141 aaagcagaaa ataaaaagct ggttcgccgt ttcttgacag aaattttcca aaatggggag
     1201 ctagagcagt ggagtgatta tgtggcagac gatttgattc agcataatca tgatattgga
     1261 caaggaagtg ctgcttataa aaactatgtg gctgaatata gtgtcacttt tgactttgtt
     1321 ttccaactct taggacaagg aaactatgtg gttagctatg gtcagactca gattgatggc
     1381 gttgcttatg cccagtacga tatcttccgt ttagagaacg ggaaaattgt ggagcattgg
     1441 gataataagg aagtcatgcc taaggtagaa gacttgacca atcgagggaa gttttaaatt
     1501 gaggacaaag aatgattgaa tacaaaaatg tagcactgcg ctacacagaa aaggatgtct
     1561 tgagagatgt caacttacag attgaggatg gggaatttat ggttttagta gggccttctg
     1621 ggtcaggtaa gacgaccatg ctcaagatga ttaaccgtct tttggaacca actgatggaa
     1681 atatttatat ggatgggaag cgcatcaaag actatgatga gcgtgaactt cgtctttcta
     1741 ctggttatgt tttacaggct attgctcttt ttccaaatct aacagttgcg gaaaatattg
     1801 ctctcattcc tgaaatgaag gggtggagca aggaagaaat tacgaagaaa acagaagagc
     1861 ttttggctaa ggttggttta ccagtagccg agtatgggca tcgcttacct agtgaattat
     1921 ctggtggaga acagcaacgg gtcggtattg tccgagctat gattggtcag cccaagattt
     1981 tcctcatgga tgaacccttt tcggccttgg atgctatttc gagaaaacag ttgcaggttc
     2041 tgacaaaaga attgcataaa gagtttggga tgacaacgat ttttgtaacc catgatacgg
     2101 atgaagcctt gaagttggcg gaccgtattg ctgtcttgca ggatggagaa attcgccagg
     2161 tagcgaatcc cgagacaatt ttaaaagcgc ctgcaacaga ctttgtagca gacttgtttg
     2221 gaggtagtgt tcatgactaa tttaattgca acttttcagg atcgttttag tgattggttg
     2281 acagctctat ctcaacattt gcagttgtca cttttgacct tgttactagc tattttgctt
     2341 gcgattccct tggctgtttt tcttcgctat catgagaagc tggccgactg ggtcttgcag
     2401 attgcaggta ttttccagac catcccgtct ctggccttgt tgggactctt tattcccttg
     2461 atgggaattg ggactttacc ggcattgaca gctctagtga tttatgcgat ttttccgatt
     2521 ttacaaaata ctattactgg gctgaaggga attgatccga gtcttcaaga ggctgggatt
     2581 gcctttggga tgaccagatg ggagcgtctc aagaagtttg aaattccact tgccatgcct
     2641 gttatcatgt ctggaattcg gacggcagcg gtcttgatta tcggtacggc taccttggcg
     2701 accttgattg gggcaggggg actgggttcc tttatcctgt tgggaattga ccgtaataat
     2761 gccagtttga ttttgattgg ggccctttct tctgcagtgc tagctattgc ctttaacttc
     2821 ctactaaaag taatggaaaa agcgaaattg cggacgattt tctctggttt tgccttggtg
     2881 gctttattac tgggtctgtc ttatagtcca gcccttttgg ctcaaaaaga gaaggaaaac
     2941 ttggttattg ctgggaaaat aggcccagaa ccagaaattt tggctaatat gtataaattg
     3001 ctgattgaag aaaataccag catgactgcg actgttaaac cgaattttgg gacgacaagt
     3061 ttcctttatg aagctctgaa aaaaggtgat attgacattt atcctgaatt taccggtacg
     3121 gtgactgaaa gtttgcttca accatcaccc aaggtgagtc atgagccaga gcaggtttat
     3181 caagtggcgc gtgatggtat tgccaagcag gatcatctag cctatctcaa acctatgtct
     3241 tatcaaaata cctatgctgt agctgttccg aaaaagattg ctcaagaata tggcttgaag
     3301 accatttcgg atttgaaaaa agtggaaggg cagctgaagg caggctttac gcttgagttt
     3361 aacgaccgtg aagatggaaa taagggcttg caatcaatgt atggtctcaa tctcaatgtg
     3421 gcgactatgc agccagctct tcgttatcag gcaattcagt caggggatat tcaaatcacg
     3481 gatgcctatt cgactgatgc ggaattggag cgttatgatt tacaggtctt ggaagatgac
     3541 aagcaactct tcccacctta tcaaggggct ccactcatga aagaagctct tctcaagaaa
     3601 cacccagagt tggaaagagt tcttaataca ttggctggta agattacaga aagccagatg
     3661 agccagctca actaccaagt cggtgttgaa ggcaagtcag caaagcaagt agccaaggag
     3721 tttctccaag aacaaggttt gttgaagaaa tgatgggaca gagactttaa acatactgaa
     3781 ctcaacttcc ttaaacgact agataaaaga atgctcagac agtttcgtct gggctttttt
     3841 gatgtgagaa tgactgaatg tcacttaaaa tggaaagaaa gagaaaattt tcatgatttt
     3901 ctaaaatttt actgtaaaga cagttgacta ttcataaaat aggtgtataa tattttgtga
     3961 actacttaac aaataagagg tttcagctca tgtcgactaa ggttagaaat cttgtgtata
     4021 ggcagttcat tatctaatag agcgttgcgt ccgaaagtct atccagacac ggctctttaa
     4081 aaacaaaagg agaaatgatg catacttatt tgcaaaagaa aattgaaaat atcaaagcaa
     4141 ccctaggtga aatgtcaggt ggttaccgtc gtatggttgc ggctatggct gatttaggat
     4201 tttcaggaac tatgaaggct atctgggatg acctctttgc ccatcgtagt tttgcccagt
     4261 ggatttattt gctggtttta ggaagttttc ctctctggct ggagttggtt tacgaacatc
     4321 gtattgttga ctggattggg atgatttgta gcttgacagg gattatctgt gtaatctttg
     4381 tatcggaagg tcgagcaagt aattatcttt ttggcttgat taactctgtt atttacctta
     4441 ttttggccct acagaaaggc ttttatggtg aggtgctgac gacactttac ttcacagtca
     4501 tgcagccaat tggacttcta gtttggattt atcaggcaca gtttaagaag gaaaagcagg
     4561 agtttgtcgc gcgtaaactg gacggcaagg gctggacaaa gtatctttcc attagtgtgc
     4621 tttggtggtt ggcctttggc ttcatttatc agtctattgg tgccaatcgt ccctatcgtg
     4681 attcaatcac agatgcaacc aatggggtag ggcaaatcct catgacagct gtttaccgtg
     4741 aacagtggat attctgggcg gctaccaatg ttttttcaat ctatctctgg tggggagaaa
     4801 gcctgcaaat tcaagggaaa tatctaattt atctcattaa cagtctagtt ggttggtatc
     4861 aatggagcaa ggcagctaag cagaatactg atttacctaa ctaggaaaag atgtttgaaa
     4921 gtgctgtttt gagatttcga ttaaaacaga tatagttgat aatcaaggat ttatagtatg
     4981 aaaaagagga tcggcgggtc ctcttttgtt gttgaaaaga taaaaaactc agtaacctag
     5041 aaataagaca actgagcttt actctatatt caatttttag gaatgagaag gtctagataa
     5101 aattggacaa cttcctggtc tgtgaaatct tgaccttttt tgagccacca ggtcaatgtc
     5161 tcgataaagt tggacacgac caagtgttgg aggtaagaag taggcatatt agggtgggct
     5221 tcttttaaat tatcagctag cacggaatag acatggtgtt ctagctcttt atggagttga
     5281 cggaggaagt agtcattttt ggaaaatagc agactggtga tatggtcttg gtttttatga
     5341 aaatggagaa agaggtgggc gaggtagtcc tcggttgaaa tggcttgctc tctttcaaaa
     5401 agatgatgga agaggtagcg gcagagctgg tccagaagaa gctccttact ttcatagtga
     5461 cagtaaaagg tggatcttcc cacatctgcg agatcaatga tatcctgaac agtagtggcc
     5521 tcgtagccct tagcattcaa aagttgtata aaagcttgat agatggcttt tttggttttg
     5581 ctgatacggc ggtcaatgtt agtcatatgg acacttaagg caaattgttc agaactgaat
     5641 aaagctgacg ttttgcttct atcctttctt tgagttttag tggataatga taatgaacaa
     5701 ggtgttcata aacctattat aacaaaggaa tgagaaatat gaaggcaaaa tatgctgttt
     5761 gggtggcttt tttcttaaat ttgacttatg ccattgttga gtttattgca ggtggagtat
     5821 ttggttctag cgctgttctt gctgactctg tgcatgactt gggagatgtg attgcaattg
     5881 gaatatcagc ttttctagaa acaatctcca atcgtgaaga agacaatcag tacaccttgg
     5941 gctataagcg gtttagcctg ctaggagcct tggtaacagc tgtgattctc gtaacaggct
     6001 ctgttctagt cattttggaa aatgtcacga agattttgca tccgcaacca gtcaatgatg
     6061 aggggattct ctggttagga attattgcga ttactatcaa tctgttagcg agtctggtgg
     6121 ttggtaaggg aaagacaaag aatgagtcta ttctgagtct gcattttctg gaagatacgc
     6181 tagggtgggt agctgttatc ctgatggcga ttgttcttcg atttacggac tggtatatcc
     6241 tagatcctct tttgtccctt gtcatttctt tctttattct ttcaaaagcc ctttcacgtt
     6301 tttggtctac actcaagatt ttcttggatg ctgtgccaga aggtcttgat atcaagcaag
     6361 taaagagtgg cctggaacga ttggacaatg tggccagcct taatcagctt aatctctgga
     6421 ctatggatgc tttggaaaaa aatgccattg tccatgtttg tctaaaagaa atggaacata
     6481 tggaaacttg taaagagtct attcgaattt tcctaaaaga ttgtggtttt caaaatatta
     6541 ccattgaaat tgatgctgac ctagaaactc accaaaccca taagcgaaag gtgtgtgact
     6601 tggaacggag ttatgagcat caacattaga aaaaagtgaa aaatacttgg gtactatctt
     6661 atttggaata gagtaatttc tttattattt aaatatttca aaaattggta agagaagagc
     6721 attgtataaa ctccagatat atgattgtta atgataaaaa tttttcgatt agatacaaaa
     6781 tgcttgactt ggagtcaact caaagttata taataagata agtgagttag aatagcgtga
     6841 attcagtgaa tgaaatgaga ggaggttagc gtgtgaatat taaatctgcc agtgatttgt
     6901 tgggaatttc agcggatacg attcggtatt atgaacgggt tggtcttgtg ccaccgatta
     6961 ctcgtactgc tactgggatt cgtgattttc aagatcagga tatcgaagcg ctggaattta
     7021 ttaagtgttt tcgttcggcg ggtgtctctg tagatagttt agttgactat atgtcgctct
     7081 accaaaaggg agatgaaacg agagaggaga ggcttggtat tttagaagag gaaaagcaaa
     7141 aattagagga gcgcttgtct cagctacaga cagctttaaa tcgtttaaat ctcaaaatta
     7201 aactttataa ggaaggaaaa ttttaaatga aatcagcagt atatacaaag gcaggtcagg
     7261 ttggacttgc tagcattgaa cgtccgcaaa taatagaagc ggatgatgtg attattcgtg
     7321 tggttcgtgc gtgcgtttgt ggttcagatt tatggaggta ccgtaatcca gaaacgaaag
     7381 ctggacacaa aaatagtgga cacgaagcga ttgggattgt tgaagaagct ggggaagcca
     7441 ttacgacggt gaaaccaggt gattttgtga ttgtcccttt tacacatgga tgtggtgagt
     7501 gtgatgcctg tcttgctgga tttgacggtt cttgcgacaa tcatattggc aataatttgg
     7561 ggggtgattt tcaggcagaa tatattcgct tccactatgc aaactgggcg ctggttaaaa
     7621 tccctggtca accttctgac tatacagaag ggatgctcaa gtcccttttg actcttgcag
     7681 atgtcatgcc gacaggctat catgcggcgc gtgttgcaaa tgttcaaaaa ggggacaagg
     7741 ttgttgttat cggtgatggg gctgttggtc aatgtgctgt catcgcggct aagatgcgtg
     7801 gagcatcaca aattatcctt atgagccgtc atgaagaccg tcaaaagatg gctatggagt
     7861 caggtgcgac agctgttgtt gcagaacgtg gtcaagaagg aattaccaag gtgcgtgaaa
     7921 tcctcggtgg aggagcagat gcagcacttg aatgtgttgg tacggaggct gctatagaac
     7981 aggcgctagg tgttcttcat aatggagggc gtatgggctt tgtaggagtc ccacactata
     8041 ataatcgtgc tcttggttcg acatttatgc aaaatatctc tgtagcaggt ggggcagctt
     8101 ctgctacaac atacgataag caatttttac taaaagccgt ccttgatggt gatatcaatc
     8161 caggtcgcgt ctttacttca agttataaac tggaagatat cgaccaagcc tataaagata
     8221 tggatgaacg taagacaatt aagtctatga ttgtaatcga ataaaaaacg aataggagtt
     8281 ttagaactct attcgttttt tatgttatcc tattcttgat ttagggtact ttctcttaat
     8341 gtcagtctgg ttcccagcat ggtcaggcta ggaattttgc gaccgtggag gacttccttg
     8401 ttaagaatat ccatacctgc tcgccccatt tcttcagtat aaactgtgat gctggagagg
     8461 ggaggataaa cctgcttggt caggctggtg tcgttaaagg aaatgaggct gacacggtct
     8521 ggtaggctga ttccagcttc ttggagcgca cgaagggcac cgatggctaa actatcgctg
     8581 gctgcgaaaa atgctggtgg gagttggtct cccaagctct gaatggcttc cttcatcaag
     8641 tcatagccag actgggcagt aaagtttcct tgaaagacca gttcatcatg atagattcct
     8701 tttgcttgac tgtagtttct gaaattttcc agccgcttat cctgaatgat ttcttcttgg
     8761 tcagtcgttt cttcaaggcc tgttagaatc ccgatacggt ccattccttg gctgaggaaa
     8821 taatcgacaa cctgtttcat agcagtgtaa aaatccgtga taatacaggt atgtcccagg
     8881 gaaagtgtat cactgtctag aaagaccagg ggtttttggt attcttcaaa ggcagaaatc
     8941 tgagctcggc taaattttcc aatgcagaga atcccaatca cttcctcgct taaggtaaaa
     9001 ggatggtcat taaaatagcg caagatatca tagtccaact cttgggctct tttttctatt
     9061 cctaggcgaa tctggtagta gtagaggtcg tccagctccc cttgttcgct gacccattgt
     9121 ataatggcaa tcttttgctt gggtttatgg gactcgcctg tcttgaggtg cttggtgtag
     9181 cccagctctt caacaacggt taaaatacgg tgtctggttt cttctgtaac agataggctc
     9241 tggtcgcggt tgaggacacg ggatacggtc gcgatagaga cagaggctag ctgtgcaatg
     9301 tcttttaagg tagccataaa tcctccttga ttaggttagt atatcatatt tttctgcttt
     9361 ttactgatat tttagtaaaa ttttagtaaa aaggattgac cttgggaaat cccttggata
     9421 caatagaaga aaacgattac acgttaaggt ggcttaacgg acagtcaaag gagaaatcat
     9481 atgacacaac atcttactgc tgaaactctt cgcaaagact ttcttgctgt ttttggtcaa
     9541 gaagcagacc aaactttctt ttcaccaggt cgtatcaatt tgattggtga acacacagac
     9601 tacaacggtg ggcacgtttt tcctgctgct atttccttgg gaacttacgg tgcagctcgt
     9661 aagcgtgacg accaagtttt gcgtttctac tcagctaact ttgaggacaa gggcattatc
     9721 gaagtgcctc tcgctgacct caagtttgaa aaagagcaca actggaccaa ttatccaaaa
     9781 ggtgtccttc atttcttgca agaagctggg cacgtgattg acaaaggttt tgatttttat
     9841 gtttatggga atataccaaa tggtgctggt ttgtcttctt cagcatcctt ggagctcttg
     9901 acaggagtcg tggcagagca tctctttgat ttaaaattag agcgtctcga tttggttaaa
     9961 atcggaaaac aaacagaaaa caactttatc ggagtcaact ctggtatcat ggaccagttt
    10021 gctattggta tgggggctga tcaacgtgct atttaccttg ataccaacac cttagagtat
    10081 gatttggtgc cacttgattt gaaggacaat gtcgttgtta tcatgaacac caacaaacgc
    10141 cgtgaattgg cggactctaa atacaatgaa cgtcgtgctg agtgtgaaaa agcagtggaa
    10201 gaattgcaag ttgccttgga tattcagacc ctgggtgaat tggacgagtg ggccgttgac
    10261 caatatagct atttgattaa agatgaaaat cgtttgaaac gtgctcgcca tgctgtgctt
    10321 gaaaaccaac gtacccttaa agctcaagca gcccttcaag caggtgattt ggaaacattt
    10381 ggtcgtttga tgaatgcgtc acacgtttct ctggagcatg attataaagt aactggtttg
    10441 gaattagata cccttgttca cacagcttgg gcacaagaag gagttctcgg tgctcgtatg
    10501 acaggggctg gttttggtgg ctgtgccatt gccttggttc aaaaagatac tgttgaggcc
    10561 tttaaggaag ctgtaggcaa acactacgag gaagtagttg gatacgctcc aagcttctat
    10621 atcgctgaag ttgcaggtgg cactcgcgtc cttgactagt caaaaggagg atctatagtg
    10681 accttagtag ataaatttgt aacacatgtc atttctgaaa gttcatttga ggaaatggat
    10741 cgaatctacc tgaccaatcg tgttttggca cgagtgggag aaggtgtttt ggaagttgag
    10801 accaatctgg ataaattgat tgacctcaag gaccagctag ttgaggaaac cgttcgatta
    10861 gagacgattg aggatagtca gactgcgcgt gaaatccttg gtactgaact gatggacttg
    10921 gtgactcctt gtccgagtca ggtcaatagt gacttctggg aagcctatgc ctactctcct
    10981 gagcaagcga tagaggattt ttatcaactc agtcagaaaa atgactacat caaactcaag
    11041 gccattgcta aaaatatcgc ttatcgtgtt ccatctgatt atggagaact tgaaattacc
    11101 atcaatctct ctaagcctga aaaggatccg aaagagattg cggtagccaa gttggtgcaa
    11161 gctagtaatt atcctcagtg tcaactttgt ttagagaatg agggttacca tggtcgggtc
    11221 aaccacccag ctcgcagcaa ccaccggatt atccgttttg aaatggttgg tcaggaatgg
    11281 ggtttccagt attcgcccta tgcttacttt aatgagcatt gtatcttttt agatggccag
    11341 catcgtccca tggccattag tcgtcagagt tttgaacgtc tgttggctat cgtagagcag
    11401 tttccaggat attttgctgg atctaatgcc gacctgccga ttgtgggggg ctctattcta
    11461 actcatgatc attatcaggg aggccgtcac gtatttccta tggaattggc tcccttgcaa
    11521 aagaccttcc gatttgctgg ttttgagcag gtcaaggctg gaattatcaa gtggccaatg
    11581 tctgtcctac gcttgacttc ggattccaaa gaggatttga ttaacttagc tgataagatt
    11641 ttccaggaat ggcgtcagta ttcagattct agtgtgcaga ttttagcaga gacagacgag
    11701 acaccgcatc acaccatcac accaatagcg cgtaagcgtg atggacagtt tgagttggac
    11761 ttggtcttgc gagacaatca gacttcagca gagcatcctg atggcatcta tcatccccac
    11821 aaggatgtcc aacatatcaa gaaggaaaat atcggcttga ttgaggtcat gggcttggca
    11881 atcttgccac cacgtctgaa agaagaagtg gagcaagtcg ctagctatct tgtaggagaa
    11941 gctgttacag ttgccgatta tcatcaggag tgggcagacc aactcaaatc ccaacatcca
    12001 gacctaacgg ataaagaaaa agcccttgca atcgtcaagg actctgtggg tgctatcttt
    12061 gtgcgtgtac ttgaggatgc aggagtctac aagcagacag aacaaggtca gacagccttt
    12121 atgcgctttg tggaacaggt cggaatttta ctagactagg agctttctcc ttgcacagtc
    12181 ctataaaaag tagtatcata gtgtcgtttg aaatatcagg aggaaacgat gaaagacttt
    12241 cattttgacg ctatatctgc ctttgaaaat tacgaaattg aaaaaatgag agatggtcac
    12301 gttgtggtga cgaccaaagt agtgaactcg tcgctcaact actatggcaa tgcccatggt
    12361 ggctatctat tcacgctatg tgaccaaatc agtggtttgg tggttatctc gctgggactt
    12421 gatggggtga cactccaatc ctctatcaac taccttaagg caggaaaact cgacgatgta
    12481 ttgaccatta aaggagaatg tgtccatcaa ggtcgtacaa cctgtgtaat ggatgtggat
    12541 atcaccaatc aagaaggcag aaatgtctgc aaagcaacct ttaccatgtt tgtcacaggc
    12601 cagcggtcag aagacagaca ggtaaggata taaagagtaa tttaatagag tgaggtgaat
    12661 tttggaattt ataagatttg ccttactcat tttttgatat tgatatgatt taattctaaa
    12721 atagaaaatt tagtaatgtg gtagaaaata caagagttgt gttttaattt ctatggtata
    12781 attaaaagca tgaagataaa agaaataaag aaagttactt tacaaccgtt cacgaaatgg
    12841 acaggtggta aaagacaatt attgcctgtt attagagaat taatacctaa aacctataac
    12901 aggtatttcg aaccttttgt tggaggtgga gctttatttt ttgatttggc tcctaaagat
    12961 gcagttatta atgattttaa cgctgaacta ataaattgct atcaacaaat taaggacaat
    13021 cctcaagaat tgattgaaat tttgaaagtt catcaggaat ataattcaaa agaatattat
    13081 ttagatttac gttctgcaga tcgtgatgaa agaatagata tgatgtccga agtacaaaga
    13141 gctgcacgta ttctatatat gttgagagtg aactttaatg gtctatatcg tgtgaattct
    13201 aagaatcaat ttaatgttcc atatggacgt tataagaatc ctaaaattgt tgatgaggaa
    13261 ttgatatctg ctatttcagt ttatataaat aacaatcaac tagaaattaa agtgggagat
    13321 tttgaaaagg caattgtaga tgttcgaaca ggagattttg tgtattttga ccctccatat
    13381 attccattgt ctgagacgag tgcatttacg tcttatactc atgagggatt ctcttttgca
    13441 gatcaagtaa gattaagaga tgcctttaag agattgagtg atacaggagc ttatgttatg
    13501 ttatcaaatt cttctagtgc tttagtagag gagttgtata aggattttaa tatacattat
    13561 gttgaagcta cccgaactaa tggagcaaaa tcttcaagtc gaggaaaaat ttctgaaatt
    13621 atagtcacaa attatgaaaa ataacgaata taagtatgga ggtgttctta tgacaaaacc
    13681 atactacaat aaaaataaga tgattcttgt tcattcagat acgttcaagt tcttatcaaa
    13741 aatgaaacca gaaagtatgg atatgatttt tgctgatcca ccttattttt taagtaatgg
    13801 tggaatatct aattctgggg gacaagtagt ttctgttgat aaaggagatt gggataaaat
    13861 ttcttcattc gaagaaaaac atgagtttaa tcgtaaatgg attcgcctag caaaagaagt
    13921 tctgaagcct aatgggacgg tatggatttc aggtagtttg cacaacatat actcagttgg
    13981 aatggcatta gaacaagaag gttttaaaat tctgaataat attacttggc agaaaacaaa
    14041 ccctgccccc aatttatctt gtcgttattt tacccattct actgaaacca ttttatgggc
    14101 cagaaaaaat gataaaaaag ctcgtcatta ctacaattat gatttaatga aagaattgaa
    14161 tgatggaaaa caaatgaaag atgtctggac cggttcttta acaaagaaag ttgaaaaatg
    14221 ggctgggaaa catccaactc aaaaaccaga gtatttgtta gaacgtatta ttttagcctc
    14281 tactaaagag ggtgactata ttctagaccc atttgttggt agtggcacta cgggtgttgt
    14341 tgcgaagcgg ttaggtagaa gatttatagg tatcgatgct gaaaaagaat atttaaaaat
    14401 tgcaaggaag aggttggagg cagaaaatga aacaaactag aaattttgat gagtggttgt
    14461 caacgatgac cgacacagta gctgactgga cttattatac agattttcct aaggtttata
    14521 aaaatgtatc tagtataaaa gttgctctaa atattatgaa tagtcttatt ggtagtaaaa
    14581 atatacaaga ggatttttta gacttatatc aaaattatcc agaaattttg aaagttgtgc
    14641 ctctacttat tgctaaacgt ttgagagata cgattattgt taaggatccg ataaaagatt
    14701 tctattttga ttttagta
//
LOCUS       DAVLGK010000049        14623 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLGK010000049 DAVLGK010000000
VERSION     DAVLGK010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14623
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.050"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(268..345)
                     /locus_tag="VXE01_001797"
                     /pseudo
     CDS             complement(268..345)
                     /locus_tag="VXE01_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(342..1631)
                     /locus_tag="VXE01_001798"
     CDS             complement(342..1631)
                     /locus_tag="VXE01_001798"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV0750659.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISKNFSEIFEKLGFYTQ"
     gene            complement(1709..2956)
                     /locus_tag="VXE01_001799"
     CDS             complement(1709..2956)
                     /locus_tag="VXE01_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0750660.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFVASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGIW
                     FLALSVNNFSLVVGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLFINSLGGALGGIYNIFFLSHPLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFL
                     TLYVSGKVSPKISTMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGISLLAIILTGLNLKNDI"
     gene            complement(3149..4000)
                     /gene="rgg"
                     /locus_tag="VXE01_001800"
     CDS             complement(3149..4000)
                     /gene="rgg"
                     /locus_tag="VXE01_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV0750661.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSAFLSVSLFTRYVREMVRKSDFLMEMSGNRNFFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            4124..4465
                     /locus_tag="VXE01_001801"
     CDS             4124..4465
                     /locus_tag="VXE01_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0750662.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            4523..4603
                     /locus_tag="VXE01_001802"
                     /pseudo
     CDS             4523..4603
                     /locus_tag="VXE01_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4719..6422)
                     /gene="ilvD"
                     /locus_tag="VXE01_001803"
     CDS             complement(4719..6422)
                     /gene="ilvD"
                     /locus_tag="VXE01_001803"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV0750663.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(6655..7587)
                     /locus_tag="VXE01_001804"
     CDS             complement(6655..7587)
                     /locus_tag="VXE01_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV0750664.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQGGEDFSKGYIELRHGEDVVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTVFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(7584..8441)
                     /locus_tag="VXE01_001805"
     CDS             complement(7584..8441)
                     /locus_tag="VXE01_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0750665.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNSGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(8445..9791)
                     /locus_tag="VXE01_001806"
     CDS             complement(8445..9791)
                     /locus_tag="VXE01_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0750666.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(9804..10088)
                     /locus_tag="VXE01_001807"
     CDS             complement(9804..10088)
                     /locus_tag="VXE01_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0750667.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELIIKICEEKGLI"
     gene            complement(10092..12122)
                     /locus_tag="VXE01_001808"
     CDS             complement(10092..12122)
                     /locus_tag="VXE01_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0750668.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            12313..13320
                     /locus_tag="VXE01_001809"
     CDS             12313..13320
                     /locus_tag="VXE01_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0750669.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAALTHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNGNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            13323..13523
                     /locus_tag="VXE01_001810"
     CDS             13323..13523
                     /locus_tag="VXE01_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0750670.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            13675..13857
                     /gene="rpmF"
                     /locus_tag="VXE01_001811"
     CDS             13675..13857
                     /gene="rpmF"
                     /locus_tag="VXE01_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV0750671.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            13873..14022
                     /gene="rpmG"
                     /locus_tag="VXE01_001812"
     CDS             13873..14022
                     /gene="rpmG"
                     /locus_tag="VXE01_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0750672.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(14514..>14623)
                     /locus_tag="VXE01_001813"
     CDS             complement(14514..>14623)
                     /locus_tag="VXE01_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0750673.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         4694 a         3094 c         2506 g         4329 t
ORIGIN      
        1 ttataactcc tttctgcttc ctatttctta acttgaattc attgtaacac atctttttct
       61 ttttgacaag tatagttgtc aaaaagttta tgatttttgt cattttgcaa aagaaaaagg
      121 tcaggagtaa gttcctgacc actttatcta tcattaatac tcttctaaaa tctcttcaaa
      181 ccacgtcagc ttcaccttgc cgtaggtatg gttactgact tcgtcagttc tatccacaac
      241 ctcaaaacag tgttttgagc tgacttcatc agttctatcc ataacttcaa aacactgttt
      301 tgagcaacct gcggctagct tcctagtttg ctctttgatt ttcattgagt ataaaatcct
      361 agtttttcaa agatttctga gaaatttttg ctgattgtct caagtgacac ttgcacttct
      421 tctcgggttt ggttgttctt gaccgtcact tgtccgcttt cgacttcact ctctcctagg
      481 gtgatgaggg tcttagccac aaagacatcg gctgacttga actgagcttt gagcttacgg
      541 ttgaggtaat cacgctctgc tttgaaacct tgttggcgaa gagcttggac tagttctagg
      601 gctttgacat ttgctccatc acccaagact gcgatataga catctagggc attttcgata
      661 gggagggcca cgccttgttt ttcaaggatg agaagcaggc gctctacacc aagcccaaaa
      721 ccaaatccag cagtttcagg gcctccaaag taagcaacca aaccatcgta gcgaccaccc
      781 gcacagactg tcaagtcatt gccctcaatc tctgtgataa actcgaaaat ggtgtggtta
      841 tagtagtcca gaccacgcac catattggta tcgatgatgt aatctactcc aagattttcc
      901 aacatctgac gcacagcatc aaaatgagct tggctttctt catcaagaaa gtccaagata
      961 gacggcgcat tctctactgc caccttgtct tctttttcct tagagtccaa gacacgaaga
     1021 ggattttcct ccaagcgacg ttggctatcc ttagacaagg tctccttgag cggtgtcaaa
     1081 tagtcaatca aggcttggcg gtaggctgca cggctctcag gatttccaag agtgttgagg
     1141 tgcaatttga caccttgaat accgatttcc ttcaaaaaat gggctgccat agcgattgtt
     1201 tccacatcgg tagctggatt gctagagcca aaacactcaa caccaatctg gtggaattgg
     1261 cgcaagcgcc ctgcctgtgg acgctcataa cggaacatag gtcccatata gtagaacttg
     1321 cttggctttt gcacttctgg ggcgaagagt ttattttcca cataggaacg gacaacgggc
     1381 gcagttcctt ctggacggag ggtaatatga cggtcaccct tgtcatagaa atcgtacatt
     1441 tccttggtta cgatatccgt tgtatctccg acagagcgac tgataacctc gtaatgctca
     1501 aaaatgggcg tgcgcacttc tgcgtagttg tagcgcttga aaatttcacg ggcaaagccc
     1561 tcaacgtact gccatttggc agattcagca ggtaaaatat cctgcgttcc ttttggtttt
     1621 tgtaatttca tagggaatcc tctttaaact taatagtctt attttaccat aaatagaggg
     1681 attaaaacag tgagaaaaaa attaggattc aaatatcatt tttgagatta agacctgtca
     1741 aaataatagc tagcaaggaa ataccaacaa atagcatcca agtcaactgt atattccata
     1801 cggctacaag tgaaaaacag gctgttccca caggtatgga taaggtaaac aagagaccta
     1861 aaaagttact ggtacgagct agaacctctg gagctagatt tttcatgagc atggtactaa
     1921 tcttcggtga aactttacca gacacataca aagttaaaaa gagaaatagc aaaccaagaa
     1981 cgacttgatt gaataaatta gccaaaccaa ctagactaag tcctacggtc gcccacatca
     2041 tcaatctagg caaggactgc ttcccaaaat aatcattgcc cgtaaggcta ctgatgatga
     2101 ttgctactaa aacacagaat tgattgataa atagtgcctc tgtgtaagaa aaattcaaga
     2161 gaggatggct caaaaagaag atattataaa ttccacctaa agcgccaccc aaggaattaa
     2221 taaacaagac agcaaagagc ataaaaccaa agtttttctg tccactttta agaaaaacga
     2281 gacgtaaatt tcggtaaatt gttaggaact ggtctttgat agaaagcttc tcatttttta
     2341 agttttcacc atcagcagat gacattgaca ggctcaattt gctttttcct aaaaagagga
     2401 tagtggctga tactaggaaa aagcaggcat tgattcccac aacgagagaa aaattgttga
     2461 ccgatagagc taagaaccag attccgaaag cttgaccacc aatagctgaa atataggtga
     2521 tgaactgtga aaaagaataa gcctccatca gatcatcttc agctactttt tccttaataa
     2581 gaggcatacg caggccacct gcaaaatcac tgatgacatc actaatgaca ttgatcaaac
     2641 acaggctaga aaaggcaaag agactagctt gctgaacaac tagggctgct agaaaaaata
     2701 gaaccgcctg aaacaaaccg ctatagacca tccatttgac cttgtccctc gtgtaatctg
     2761 cccgaatccc tgcaaaaact gtaaagaagg tcggaagaat catgacaata ttcgccatag
     2821 caacagcaaa agatgcttgt gacaaggtcg atgcatagac gataaagacc aggttgaaaa
     2881 tcgaagcaac aaaagcattg aagaagcgtg acaaagtcaa aattctataa gctggatttc
     2941 taaacaatag tttcatagat aatctccctc cttgttcgaa cctctatatg aagtatgact
     3001 atagtatagc acttagaaat ttgagaggga gaactcttga atatatgcaa caaataaaat
     3061 gagcaaaaag aaacgataga acttttgtaa tgacctgaga gagggcaata gttctatcgc
     3121 ttcaaatttt ttcttggttt gcagatattc aacattcggt cgtatttcta tagtattcgg
     3181 cagatttatt acagccaagc atctcaaaaa tacggacagc atcctccatc tttttctggc
     3241 cttccttgac tctaccttgc ttgctatcaa ggagaccttc tgcccacaga taaacaattc
     3301 ggaaataggt ctcattttcc ttgtagaaat gctcttcgat aacacgttta aaataatagg
     3361 cattggtaaa ttcttcacac tcaatactag ctaaaaagcc attcaatagt atagtatgaa
     3421 aaaagtttcg attaccagac atttccatta gaaaatcaga tttacgtacc atttctcgta
     3481 catatctagt aaaaagagaa acagataaaa aggcagaact gactgaaaat aaattgagtt
     3541 catagattcc ccagatctcg gtagaaaaca aataatcatg aaggactttt ccttcctctg
     3601 ctgttaactc taccctttca tccatgctct tcatataaga cttgatcata atggcattta
     3661 gaatatgttt ctgtttgttg tgagaatggg catgcttttg atactccctg cgatataagt
     3721 cctcaagagg tgctatattc tttggttcca agacatctgt aatttctttt ctcaactcag
     3781 aatctgtatc atactggaaa cctctcgcca gaaagaggat ctcctccaca ctggcagata
     3841 tattttccag agcaaataga aacttttcca ccgaaagctc actctgacct gtttcaaaac
     3901 gggacaacat agacggcgaa aattgtcctc cggttgcttg tctcagtgag atatttcttg
     3961 attctcgtaa ttgtctaaag acttttccaa tctgctccat agacttcccc ttgattccgt
     4021 attttcttca ttttatcata tttttcagaa aattcatcaa aaacttgcca aattgtcaga
     4081 attatgagaa aatagaggat atttatcacg tggagggact gctatgagag acgatatcaa
     4141 aatcaatgac cgtgctttgg ccttgcaaga ccaaattatc gaaaaactag agaaagtttt
     4201 tgatacagat gtggaattgg atgtttacaa tctaggtctg atttatgaaa tcaatctgga
     4261 tgaaacgggg ctctgcaaga ttgtcatgac cttcaccgat actgcctgtg attgcgccga
     4321 aagcctgcct attgaaatcg tggcaggtct gaaacaaatc gagggtatca aagatatcaa
     4381 ggttgaagtt acctggtcgc ctgcctggaa aatcacacga atcagtcgct atggccgtat
     4441 tgcccttgga ctaccacctc gttaagcagg ccaatcactt ttaaagatga aaaaagcaag
     4501 ccgaaaatgg cttgcttttt gatactcaat gaaaatcaaa gggcaaacta gaaaactagc
     4561 cgcaggttgc tcaaaacact gttttgaagt tatggataga actgacgaag tcagctcaaa
     4621 acactgtttt gaggttgtag atagaactga cgaagtcagt aaccatacct acggcaaggc
     4681 gacgttgacg tgatttgaag agattttcga gtatgagttt attttttacc tgacttgtcc
     4741 atattccaga agtctgtcac ggctccgcgt gaagcagatg atacgatgtg ggcatattta
     4801 ccgaggacac cacggctgta aagtggtggc aaggttgttt ctgccttgcg tttttcaagt
     4861 tcttcttcgg atacggccat ggaaatttct ttggtatctt ggtcaaccgt aacgatatcg
     4921 ccggtacgga gataggcaat tggtccacca tcctgagctt caggagcgat atgtccaaca
     4981 accagaccat aagtaccacc agagaaacgt ccgtccgtca agagggccac cttatctccc
     5041 tgacctttac caacaatcat tgatgaaagt gacagcatct caggcatacc aggaccacct
     5101 ttaggtccaa caaaacgaac aacgactaca tcgccatcaa cgatttcatc tgtcagaacg
     5161 gcctgaatcg catcttcttc tgagtcaaag accttagctg gcccaacgtg acgacgcact
     5221 ttaacacctg ataccttggc aactgcaccg tcaggagcaa ggttcccgtt caagatgata
     5281 agcggaccat ccgcacgttt tggattttca agtggcatga taactttttg gcctggagtc
     5341 aagtctgcaa agtcagccaa gttttcagct acagtcttac cagtacatgt gatgcgatct
     5401 ccgtgaagga aaccatttgc caacaagtac ttcataaccg cagggacacc accgacttcg
     5461 tagaggtctt ggaagacata ctgaccagat ggtttcaagt cggccaagtg aggcacacgt
     5521 tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat ttgcggcatg ggcaatggcg
     5581 agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca tggttacagt gatagcatct
     5641 tcaaaggctt cacgagtcaa gatatctgat ggtttgagac caagttccaa catcttaaca
     5701 acagcacgtc ctgctgcttc gatatcttct ttcttatcag ctgattcagc tgggtgagag
     5761 gatgaccctg gcaaactcat ccctagaact tcgatagcag ttgccatggt attagcagta
     5821 tacataccac cacaaccacc agggccaggg caggcattac attcaagacg tttcacgtcc
     5881 tcagctgtca tgtcaccgtg gttccatttt ccgatacctt caaagacaga aaccaagtcg
     5941 atatctttac catcaagatt tcccggtgca atagttccac cataggcgaa aatagctggg
     6001 atatccatat tagcaatagc aatcatagat ccaggcatgt tcttgtcaca gccaccgata
     6061 gcgacgaagg catccacgtt gtgaccactc atagccgcct cgatggagtc cgcgatgatg
     6121 tcacgagatg ttagagagaa acgcatacca ggcgttccca tagcgatccc gtccgctacg
     6181 gtaatggttc caaactgtac aggccaagcg cctgcagatt tgacaccttc tttagccagt
     6241 ttcccgaaat catgcaagtg aatgttacat ggtgtatttt ccgcccaagt cgaaatcact
     6301 cccacaatcg atgtttcaaa gtccttatct gtcataccag tcgcacgaag catagcacgg
     6361 ttaggtgatt taaccatgct gtcatagatg ctactgcggt gacgtttatc taattcagtc
     6421 atcttatccc tcccatttca gtttttacta ttatagcaca atttaaaggc aatgaacaga
     6481 ataaaattct tgaattttca gaaaattcta tacgcatgtg aaatatttaa aattaaaaac
     6541 aacaaagcgg attagtgcac tttctgatga ccagaatatg ctttttaatc cgctttcttt
     6601 aaataacgta atgtaatttt tacagaaatt ctttcagata agtgtattta acatctatct
     6661 tgcattataa atttctagaa ccttctcttt tatattcgat tcactcaaac catactcatt
     6721 aagaagataa tccattttcc ctacttgacc aaatctttct tgaacaccca tccgatgaat
     6781 ttttgttatt ccatcatcag agaataattc acataaagca ctgccaattc cacctatctg
     6841 attgtggttt tctacagtaa atacagtttt tccacttaac attgttttta tctgttctgg
     6901 tatcggtttg attctaaata aatctatcac acctactgaa taacctaatt tagacagttc
     6961 atctgcaact cgaatacttg gagcaaccat tatgccagaa gcaactatta caacatcttc
     7021 accgtgtctt aactcaatgt agcctttaga aaaatcttct ccaccttgat atacagcctc
     7081 tggagctttt ctaattgttc gaatatattt tagtcctttt aagtctaatg tctggttcaa
     7141 tatttcacga aattggatat catcagttgc ttcaaaaatg attgatttag gaattaaacg
     7201 taacaagccg atttcttcaa atggcatatg tgttccacca ttcatctctg ccgttactcc
     7261 tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat ccaagagaaa taaataattg
     7321 atcaaatact cttcgtgaag caaaaggacc aaatgtatga agataaggtc taaacccctg
     7381 aatagacaag cctgctgcaa ggccgaccat ttctgcttcc ataatcccaa cattcacata
     7441 acggtctccg aagtcctttt caagattatg agtagccatc gaacttgaca aatcggcttc
     7501 taagactact atatcagaat aactttgatt agcctctaaa aggaagtctc tatatacatg
     7561 ccgtaattct ttcgtacttc tcatcattct gtttcctcca attcctgact taatctttct
     7621 acaactgaag ttaacatttg tttctcctct acagtagggc gaagatgatg attggatttc
     7681 atttcttcca gctcttgaac cccttgacct ttaatagtat ctaatacaat gcacttaggt
     7741 gatgaattat ttgactgttt taattggaca atcccttcat aaatttctct aatatctgaa
     7801 cccttgaccc taatggattc aaatccaaat gctgaaaatt tttctacgaa atcacctgaa
     7861 ttacaaatat cctttgtaaa accatctaat tgttttttgt tatcatcaac aaatacaatt
     7921 aagttggata actgttgatg agaagcaaac tgtatagcct cccaacattg tccctcattt
     7981 aactcaccat ctccaacaat agcgtaagta taaaagggac tctttcttat tctctgacca
     8041 tatgcaagtc cagttgcaac actaattcct tgtcctaaag agcccgttgt catatctatg
     8101 cctggcgtta gatttctatc aggatgagac ggtaatttgg ttccatttgt atttaaagaa
     8161 tataagaatt ctttgtcaaa gaaaccattc aaatagagtg tactgtatag agctggtcct
     8221 ccatgacctt ttgataatat gaaataatct ctatctcgtg ctgcaaatat ttctggagtc
     8281 attggcatta tttcaccata aagcactgct aaaacttcta cgatagacaa acttcctccg
     8341 taatgtccga atccaagatg attcaatgtt ctaagagtat ttaatcggat gttagtcgca
     8401 aattttctta acccatcttc tctattttta cttaaaatca tcccttattc ctcctttgca
     8461 gatggctttt taataaagga tactccaaac ataactgcta aaataagaac aagaccaatc
     8521 acaatgcctg cttgtgagcc aaattgattt aacattccta aaataattcc tgatagacca
     8581 aaatctgcat ctgagaaagt tgatccttgg aaaccaagtc ctcccaaaac tggcattaaa
     8641 aagactggaa gaaaactgat taaaatacct tgtaaaaatg ctccaatagt ggctccacga
     8701 acaccaccag atgcattccc aatgacacct gcagtcgctc cacagaagaa atgaggcaca
     8761 acgcctggta agataacaac cgttcctgaa gcaatcataa ttgccatact tactaaacca
     8821 ccaacaaaac tagagataaa tccaattaga actgcattgg gtgcataagt ataaacaatc
     8881 ggacaatcca aagcaggttt tgaattaggt acaagacgct ctgaaatacc tttaaaggct
     8941 ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa taacaaatac ccctgctgca
     9001 aattgacctg ctaattgtaa agcataaact agaccacttg taccactact gatttctttt
     9061 tctatatatt ctgaccctgc aaagatagct acaataatgt aaataactgc catagataaa
     9121 gtgatactaa cagtactatc acgtaaaaaa gctaaactct ttggaaattt aatgtcctct
     9181 gttgattttg atttgtcacc gataaggcta ccagtaaaac cactcaacca atatcccaaa
     9241 gaactgaaat gacctaaagc caccttgtca tttccagtta attgaaccat atatttttgc
     9301 acaaatgctg gggaaatact cataataata ccgagtgcta atcctcctag taagataaga
     9361 ggcaagctag taaagccagc aactgataaa atgaccgcaa tcatacacgc catatataga
     9421 gtgtggtgcc ctgttaaaaa gatatattta aatcgagtaa aacgagcgat taagatattg
     9481 aacaccatgc ctgcaaacat aatcattgca gtagctgagc catatgttgt taaagctaca
     9541 gctacaattg cttcattatt cggcacaacg ccagataaat gaaaagcatg ctcaaacatg
     9601 gtaccaaatg gatttaaaga attttgtaca attcctgcac caccagatac aactaagaaa
     9661 ccaacaaagg tcttaattcc acctttaata atatcaggta atttcttctt ctgaagaact
     9721 aatcctaaaa ttgcaattaa agctactaaa atagctggtg tactaacaat atccaatatg
     9781 aacttcatca tgacgctagc ctcctatata agtccttttt cttcacaaat tttaataatt
     9841 aattctcgta gttcgtccat atcaataata ctatttaaga tacgaacatc tccaagatga
     9901 ctagctgaat cagctagatc acgaccaaca atccaaatat cagctgcatt tggatctgct
     9961 ccacctaaat cataatgttc aacttctaca tccgaaacat tcaaatcact caatacagat
    10021 tcaatattca tctgtaccat aaaacttgaa cctaatcctg aaccacaagc tgtaccaatt
    10081 tttaacatta tctaatcctc ctgtttaatt atcattttaa tatcatcata gttttttgat
    10141 gatattaaag tttgaacatg atttttatct cttaaaattg ttgttaaatg tgacaaagcc
    10201 tttaaatgac tctcattatc aatggctgca atacaaatca acaatcttac ctcttgttct
    10261 ggattatcca ataaataaat cggttcttcc aaaactaaca ttgacattcc tatttcattc
    10321 acaccttcat ctggccgagc gtgaggaatt gctactccct tccctaaatt aataaaaggt
    10381 ccaaactctt ctactttttg aatcattgcc tcagggtagt tctcagttat cttatcttga
    10441 tccaaaagcg gtttagctgc taaacgaatc gcctccttcc atcctaattt ttgcgaacta
    10501 acctgatagg tttctttggt aataagttgt tctagcactg gtacaatttc ctttctatca
    10561 tttttttgat aaagataatt ctttaacgcc aatcttaatt ccaattcttg tgtaataatt
    10621 ccatatcttt tgacaatatt caggatttgt tcaatctcaa aatctccata ctctaaattc
    10681 ggaaaatctt ttaacactag ttctactagt tgtattgctt gctcttcagt catcataacc
    10741 gaaactagat aatttggctt ttctgtctcc acttttatgg tagaaaaaac catatcatag
    10801 tcactactag ctttcacctg taaatcatca atctttgagg ttcctataaa ctcaatttga
    10861 ggaaataatg ctaatagatt ctcttttaac atcaatgaag aactaacacc attaggacaa
    10921 atgattgctg ctttatagca tttttgaggc aaagtatctg ctttctttaa ataacctccg
    10981 aaatggataa caaaatatgc tgtttcacta tcaggtatgg gattgtcaat agcgtccatc
    11041 aagggcatca aagaatcttt gactaattca aataaatcag gataatgttc tttaacatgc
    11101 aatacatatt catttgaact aggtaggccg aactttaatc tatagtaagc cggtataagg
    11161 tggcggcgaa gattttctct caatccttcc ctttgtttaa aatgtaacaa agaaatatct
    11221 tccattctac ttataatagc ctctgttaat tgattaaagt aaaccggagc aacatctact
    11281 tcaccttcaa agcaacttga taataaaacg gtgatatagc gataatcatc ctcagaaaac
    11341 accgtatcta taattcccaa atcaaccact gtatccaata aaatagtggt tatatcttga
    11401 ataacaggag atactaatgt ctctgaaaga catactcttt caacatccct ttgataccta
    11461 cacagaatga atactaaacc gaaaaggtaa acttttaatt gattaacaat aggtactagc
    11521 tgtagcttct cataataatc tttaactacc tgatcaatca aatcataagt taatgaatac
    11581 ccccaactgg ataaaacata atccaaaccc caaatcccta tggaggattc cagcaactca
    11641 ctaaccattt gaaaagctaa acggtgctta ttccactctg aaccgtgtaa agtataacct
    11701 tttgctctac tgtaccctag ctccaaatca ttatctaaca taatctttct taatgattga
    11761 atatcagata aggttgtatt cttacttact ttcaaaaagt cttggtaatg attattcgat
    11821 ataaaatcta atcggcaaaa agtgtaaaga tagattaaag ctaagcgagt cgactttggt
    11881 aaaaccaatt catccgactt aataatatct gtcaaagact gcttcgtacg atttgataaa
    11941 ctatatcgac cttgtttttt atccagcact atccctttat tagctagata aggcactaaa
    12001 taatctattc cttctttgac ttcctttata ggtaagctca ccttaacaga taattcatat
    12061 aatgatagct cacaatgatc catcaaagtc atcaaaataa ctagtgctct ataatcaaac
    12121 atttctcttc ctttctaact acaattatag tgtaaaaatt ataagaataa aagagtattt
    12181 gagcacaata taatctcacc ttttaaaaga aattattggg ctgaaacttt ttagtgatta
    12241 ttttcaactt tctattgact tttaaaaaca aagtgatatc atttagatat caaataatgg
    12301 gaggtcattc ttatgactga aaaactaatc aattcaaaac caaatggtgt attcgcattg
    12361 attctcattg aattgacgct cgtacttggt gtctttatat ttataatggg tgttggttcg
    12421 gaaaacattt ttggaattat tatcggacct ttactaatcg taattgcagc gctaactcat
    12481 gctggtttaa aagttgtcaa acctcaggag gctctggttc tgacactctt tggtaactat
    12541 acaggtacca tcaaagaacc tggcttttac tttgtcaatc ccttcagcgt agcagtcaac
    12601 cctgcaaacc acactcgact tggacaaagt ggtgatgtta gcacaaaatc tcctttttta
    12661 ggagctaaat catcaaatgg caatgatgta aatcttgaaa ttggcaagaa acacatttcc
    12721 ctcaaagtca tgaccttgag caattctcgt caaaaaatca atgattgctt aggaaaccct
    12781 gtagaaatcg gtatcgcggt aacttggaga gttgtcgata ccgctaaggc agtcttcaac
    12841 gttgataact acaaagaata tctttcattg caatgtgata gcgccctccg taatattgtc
    12901 cgcatctatc cttacgatgt gtctcctaat gtggatacta cgggtgacgg gcaagcagat
    12961 gaaggtagtc tccgtggctc tagcgaaatt gttgctaacc gtattcgtga agaaatccaa
    13021 agtcgtgttg aggatgctgg cttggaaatc cttgaagcac gtatcactta cctagcttat
    13081 gctccagaaa ttgctgccgt tatgcttcaa cgccaacaag catctgccat tattgatgca
    13141 cggaagatga ttgtagatgg tgctgtagga atggttgaaa tggcactaga acggctcaat
    13201 gaaggggaat tggtagaact tgacgaagaa cgaaaagctg ccatggtttc aaatctcctt
    13261 gtcgttcttt gtggcaatca tgatgcacaa ccaattgtca acacaggaag tctttactaa
    13321 agatggctga agctaaaaaa aagcagatcc cccttcgact ctcaacaaag ttatacgctg
    13381 cactcgcatc atgggcagaa gacgactttc gttcagtcaa tgggcaaatc gaatatctcc
    13441 tcacagagtg tgtcaagcaa cggaaaaaag acggaaaata cgtatcagaa accattgacg
    13501 agccatttga gattgatatt taacatcttc tcctgtctgc cgtgtcggat aggagaattt
    13561 tttcatcttt ttttgtcaag taactttact ttacaaaaaa aatgtgttat cctagtatgg
    13621 ttgatgaaaa tcagtagatt gaatcgaata taaataccta aaggagaaat caaaatggca
    13681 gtacctgcac gtcgcacttc aaaagcgaag aaaaacaaac gtcgtacaca ctacaaagta
    13741 acagctccat ctgtaaactt tgacgaaact actggagatt actcacgttc tcaccgtgta
    13801 tcacttaaag gatactacaa aggacgtaaa atcgctaaag ctgcatcagc tgaataatag
    13861 aagggagata ccatgcgcgt aaatattaca cttgaacaca aagaatctgg tgaacgcttg
    13921 taccttactt ctaaaaacaa acgtaacact ccagaccgcc ttcaattgaa gaaatactca
    13981 ccaaaacttc gcaaacacgt tgtgtttaca gaagtgaagt aagcattcaa tacgaatcaa
    14041 tacagaagaa aaacgcttga tcagcgtttt ttctttttgt taatttcact atattgcaag
    14101 ggaaatcatt cgaatgacta cctttttcac tacctttttt gaaataagaa tacggattcg
    14161 gacgattaaa agtaagagaa actcaaatgt aagttggggt tccttttttg tatatttttc
    14221 aaataacgcc tctacactat ttgtagcaaa ttcaccaact acagttgtat cttagttaaa
    14281 ataagttaga atatgtaagt gagtaccaga tataccaaga catcgtcacc atctaaggta
    14341 tattcaaaat acaaaagttg accaactaga tttctgaata tccttatata tccattctta
    14401 aaattggttt aaatagcgta gtcttttaaa ctagttttga gaatccaaaa aatcttccta
    14461 catatgtaag aagatttttt agttcagaat gattagattt agctaatgga tacctatcct
    14521 acccactcac cgttagcatt gactcgatag ccatcgggtg tagtcgtgtt tactaataaa
    14581 tctcctgaat tataggtata gtaccattta ccagaaactg taa
//
LOCUS       DAVLGK010000050        14291 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLGK010000050 DAVLGK010000000
VERSION     DAVLGK010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.051"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..821)
                     /locus_tag="VXE01_001814"
     CDS             complement(<1..821)
                     /locus_tag="VXE01_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0750674.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYDKEEEYDKKEACLEEI
                     EDLFYEQLPNEEKVWFEATRATIDVIRSGQPEYGETVLDDYFKTIYDKELFLINELEV
                     INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIAPEYLFALSNTLFSGLACL
                     DNLSSYDSLGAYIFSLNHIMEKTQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQ"
     gene            complement(893..1453)
                     /gene="rnmV"
                     /locus_tag="VXE01_001815"
     CDS             complement(893..1453)
                     /gene="rnmV"
                     /locus_tag="VXE01_001815"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV0750675.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(1453..2226)
                     /locus_tag="VXE01_001816"
     CDS             complement(1453..2226)
                     /locus_tag="VXE01_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV0750676.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(2531..3184)
                     /locus_tag="VXE01_001817"
     CDS             complement(2531..3184)
                     /locus_tag="VXE01_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV0750677.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKPETTPGGDKGGNTGNSD
                     ANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGVQAIAMVTVPKRPVAPKTT
                     SAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVVATSGFALLGRKTRRRK"
     gene            complement(3447..3581)
                     /gene="rpmH"
                     /locus_tag="VXE01_001818"
     CDS             complement(3447..3581)
                     /gene="rpmH"
                     /locus_tag="VXE01_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV0750678.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(3726..4940)
                     /locus_tag="VXE01_001819"
     CDS             complement(3726..4940)
                     /locus_tag="VXE01_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0750679.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(5096..5401)
                     /locus_tag="VXE01_001820"
     CDS             complement(5096..5401)
                     /locus_tag="VXE01_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750680.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLLYPGFIG
                     FLVFHVLYHLIYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            5563..6015
                     /locus_tag="VXE01_001821"
     CDS             5563..6015
                     /locus_tag="VXE01_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV0750681.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(6050..7438)
                     /locus_tag="VXE01_001822"
     CDS             complement(6050..7438)
                     /locus_tag="VXE01_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0750682.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            7504..8466
                     /locus_tag="VXE01_001823"
     CDS             7504..8466
                     /locus_tag="VXE01_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV0750683.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKNYMEG"
     gene            complement(8495..8788)
                     /locus_tag="VXE01_001824"
     CDS             complement(8495..8788)
                     /locus_tag="VXE01_001824"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750684.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDRTDEVS
                     SKHCFEVADETDEVSSKHVFEVVDETDEVSSKHVFEVVDETDEVSNHTYGKAT"
     gene            complement(8852..9862)
                     /gene="ccpA"
                     /locus_tag="VXE01_001825"
     CDS             complement(8852..9862)
                     /gene="ccpA"
                     /locus_tag="VXE01_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV0750685.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(10287..10886)
                     /locus_tag="VXE01_001826"
     CDS             complement(10287..10886)
                     /locus_tag="VXE01_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0750686.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQTKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSEKLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(10888..11985)
                     /locus_tag="VXE01_001827"
     CDS             complement(10888..11985)
                     /locus_tag="VXE01_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0750687.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(11985..12722)
                     /locus_tag="VXE01_001828"
     CDS             complement(11985..12722)
                     /locus_tag="VXE01_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0750688.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGDINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(12724..13608)
                     /locus_tag="VXE01_001829"
     CDS             complement(12724..13608)
                     /locus_tag="VXE01_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750689.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(13595..13789)
                     /locus_tag="VXE01_001830"
     CDS             complement(13595..13789)
                     /locus_tag="VXE01_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750690.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(13786..13992)
                     /locus_tag="VXE01_001831"
     CDS             complement(13786..13992)
                     /locus_tag="VXE01_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750691.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         4217 a         3292 c         2547 g         4235 t
ORIGIN      
        1 ttctgataga actgttcggc agaaacataa tcattgttta ttattagaga taatttccac
       61 tccaacatta atataattgg tttcttctgg aaatcttgtg ttttttccat tatatgatta
      121 aggctaaaga tataagctcc tagtgaatca taagacgaca aattatccaa acaggctaga
      181 cccgaaaaca aagtgttact taaagcaaac agatattctg gtgcaattaa ttctacatga
      241 tttgtcaaac gaactaaaaa cgaatgaatt ctgttaattt cttcaatctg attttgacct
      301 tgttttatct ttgtaagcac tatagcaaaa tataagttga taacttctaa ttcatttatc
      361 aaaaacaatt ccttatcata aattgtttta aaataatcgt ccagtacggt ttccccgtat
      421 tctggttgtc cgcttcgaat aacatctatc gttgctctag tagcttcaaa ccatactttc
      481 tcctcattag gaagttgctc ataaaataaa tcctctatct cttccaaaca cgcttctttc
      541 ttatcatact cctcttcttt atcatagatt ggttcacgta aaatctggta tttcaattct
      601 aaataagcag aaggaagagc tgaaaaatcc ggcataaggc tataaactgg aactcctagc
      661 cggcgagcaa tatagtctaa cttgggcaaa ctcggttgcg aagctccact ttcaattcgc
      721 gacagttgac gaactgtcag ttcttgctca tctccacaaa aatctggacg actaattcct
      781 ttttctatcc gaatctcttt aattttttga ccaattaaca tcagacgcct cctcttctac
      841 ctgcttcgaa aaatactgtg aaacttaaaa aattgtaacg gctacatctt tcctactcat
      901 aagatttcat agcttcttcc acttctgcca aagtaacccc aaacaactct aggcgtttga
      961 ggagttgctt gccgttagaa tagccgattc ggagagtctc tccgagatat tctctacgct
     1021 tacggctgtc tgcccctgct agaaaaccaa ggcgaatcaa atcgctacga ctaatgtcaa
     1081 actgactctc atgttcaaat tgttctgtca cctgagctag agccgttttc aggtcttcat
     1141 agctggcatg ctcaattccc agagaacgcc ccttggtctt ggacttggga acagcttcat
     1201 ctcgcttgag aaaggcatgc tgaactgttg gaatggccgt catgatcatg cgccgaatcc
     1261 gctccccatt aaaatctggg tctgtaaaga caatgactcc atgacgttgg tgtagacgct
     1321 gaattcgctc tatatcctga tcattgatgg cagaacctcg tgtctcatag gtctccacat
     1381 cgaaataacg cttgagattg accgtatcat cgcgaccttc aaccacgata acttgagaaa
     1441 ttttctcttt cattacttgc tgtccaatcc aaaaattcgt tctgcatttg cagtcgttgc
     1501 taccgccagc tcttctgtcg tcataccacg caagtcagcg ataaagtcga ccacatagcg
     1561 agtataggct gttttatttt cacgaccacg cttgggtaca ggtgctaagt aaggcgcatc
     1621 tgtttccacc aacatcttgt ccaaaggtaa ctctttagct gcttcttgga ggtcagttgc
     1681 cttcttgaaa gtcaccactc ctgagaagga aatggtcata ccaagatcca caaacttctc
     1741 tgcccactca agcgtccctg aaaatgaatg catgatacca ccacgaggac caacgccctc
     1801 actcttgata atctcatagg tatcttccag cgcatcacgg gtatggacaa caaaaggcaa
     1861 atccaagtcc ttagatagct gaatctgacg gcgaaaaacc tgctcctgca cctctttagg
     1921 cgctgtcatc caatggtagt ctaagccaat ttcacctaaa gccacaacct tgggatgttt
     1981 taacttatcc aacaagtaag cctcaacttc ctctgtataa gtaccagctt ctgtaggatg
     2041 ccaaccaata gtcgcataga gctgctcata ctcatctacc aactccaagg cacgctcaat
     2101 cgtcggttta tcaaaaccaa caatattcat ctgtgtcaca cccatctcat cagccaaggc
     2161 aatttcttct gcctcacgac ctgcaaattc ttctacattc aagtgtgtat gtgtatcaaa
     2221 aatcatctct tctaacctcg ttttctatct tctattatac caaaaaagag gaggggcacc
     2281 taatttttcg gtttcccctc ctctcttcaa tagagagcta ttctgctatc ttttctatcc
     2341 gatattgccc atctcctatt ccacagttag agacagaaga gattggctac attgatagaa
     2401 tattcctatt cagctaaagt atgtgattat cttgggttct cacttttctc acccatcact
     2461 aggattgatg acttctcaaa atccccctta taatctaact ttaagtagag aatagaattt
     2521 tctagctgtt ctattttcta cgtctagtct ttcttcctag caaagcaaaa ccacttgttg
     2581 ccaccactag accaagacta gcaagtgctg cacttgatgc tgaacctgtg ttaggtaatt
     2641 gtttgccagc aggtgactgg taggtaacat cttgcattgt tcctgcagtt gcttgcggtg
     2701 cacttgttgt cttaggagcc actggtctct taggaactgt aaccatggca atggcttgca
     2761 ctccaatcgt ttctgcttcc ttcacatctt ccatagtttt cgcattttca atctctttga
     2821 gagctgcttg tttttctgct tccactcttg ctaaaagttc tgctttttct ttatcagaaa
     2881 gcggtgcgcc tttgatttca tcctgcttgt ccttggctgc tttttcaatg gcatttttag
     2941 ctgattcttt ttcagtagct aattgcttag aagcttgtga ttgagctgag ttttgtgaac
     3001 ctgtgtgagc tgatccaccc gcctggctac caccgcctgc attcgcatta gcatctgagt
     3061 ttccagtatt gcctccctta tctccacctg gtgtagtttc tggcttatac tctggtgtag
     3121 cttcttgagt tacagattca cctttcgcag attgttgaac tgtatctttt cctagaatcg
     3181 tcactactga accatctggg aatgtgattg ttgctgtgcc atctccagct acttcaactt
     3241 tatagtaaaa taaaataata acaggacaaa tcgatcagga cagtcaaatc gatttctaac
     3301 aatgttttag aaacagaggt gtactattct agtttcaatc tactataaca tcgcttccga
     3361 atccatttgc atctactgaa cttttttaca aaaataaaaa tcagtagact cgagttccta
     3421 ctgatttttg atagaattcg tttggattat gcagccaaaa ctttgcgtcc tttacgacga
     3481 cgagctgcca atacgcgacg accattttta gttgacatac ggttacggaa tccgtgtttg
     3541 cgcgcacgac gaagtttact tggttgataa gtacgtttca cgatgaatac ctcctcatag
     3601 attttgtatt cgtttagccg gctataaagt gatcagttac taaacatact ttactattct
     3661 atctgattct ttcacttttg tcaatagctc taggcaaatg tttccagctt tttcgaatgc
     3721 aagccctatc tacgatactg tttcaagaaa cgagtcatct tttcttggat ttgggctaac
     3781 tcatcaacac gaggaaggta aacgatacgg aagtggtctg gttcctgcca gttaaagcct
     3841 cgaccatgaa ccaagagaac cttttcctgc ttcaagaaat caaggacaaa ctgctcatca
     3901 tcatcgatac ggtacatatt gcggtcgatt tttgggaaga tatagagccc cgccttgggt
     3961 ttaacggcag acaaacctgg aatatcttga atggcattat agatgaaatt tctttgctcg
     4021 tagattcgtc caccaggaag aagcaattca tcgactgatt ggtgaccccc caaggaagtt
     4081 tgtacgactt gttgggccaa aacgttagag caaaggcgca tattggacag catattgagc
     4141 ccttcgatat agcccttaac atgagtctta gggccagaca agaccatcca acccacacgg
     4201 aaacctgcta tgcggtggga ttttgacaga ccattcatgc tgacacagaa gacatctggt
     4261 gccaagctcg ccacaggcgt atgcacatgt ccgtccatta ccatgcggtc atagatttca
     4321 tccgcaaaga taatcaaatc gttttgacgg gcaatctcaa taatctccag caagagttcc
     4381 ttaggataaa gggctccagt tgggttattt ggattgataa ggacaattgc cttggtattg
     4441 gaagtgattt ttgacttgat atcgtcaata tctgggtacc attccacagc ttcatcacag
     4501 atatagtgaa cggcatttcc tccagctagg ctgacagccg ccgtccatag aggatagtct
     4561 ggcattggca ctaagacctc atccccattg tccaaaagcc cctgcatgga catgacaatc
     4621 aactcactga caccatttcc aaggtaaata tcatcaatat ctacgtttgg gaatttcttc
     4681 agctggcaat actgcatgat ggccttacgg gctgagaaaa tccctttgga gtcagaatag
     4741 ccttcactat cacgtgcatt cataatcaag tcatgaatga cctcgtctgg cgctgtaaag
     4801 ccaaattctg ctggatttcc tgtattcaga cgtaaaatct tttctccatt cgctcgcatc
     4861 cgcatggctt cttccaatac aggaccacgg atatcataag caacatgctc taacttacta
     4921 gacttgttat attctttcat cttgtttcct caattcatca ggatagtaac attataccac
     4981 tagaaagaga atgcgacaag tttactgaaa tgtgttacta gtttcgtata gaaaaaaaac
     5041 cttgctaaag gcgaggttaa gaacgtagag atagcaggta ttttgcaaag acacatcaca
     5101 taccaaaaga taaacctaga aaaagcaagc ctagaaagga gtcataaaga agattaaaca
     5161 tgaggaaaag cccccatatc atcaagtaat cccaacgccc acttcgtttt gcaactagaa
     5221 ataagattag atggtagatt agatggtaga gtacatgaaa gactaaaaat ccaataaaac
     5281 ctggataaag aagcggtacc agactctcta attgccagat catgatcact tctaccaaga
     5341 ctgaaactag gataattcca taatacagga aatttgattt ttgaaaagag tttttcatca
     5401 ttctcccttc cttcacttct ttcctgctat cctttctttt attttatcat atatttatat
     5461 agattttaag ccctaatatt cttttgaaaa atactttttt tgctttactt ctatagtgaa
     5521 aaggtttaca attatagtaa gaaaatttca ggaggtttca ttatggcaca acgttaccaa
     5581 aatatcatgg tcgcaatcga tggttctaag gaagcggact tggcttttgt caagggagtt
     5641 cattctgctc tacgaaacga cgctaaactc accatcgcac atgttattga cacacgcgct
     5701 ctccaaagcg tatccacctt tgatgctgaa gtttacgaag aactccaagt cgacgctgaa
     5761 agtctgatga aagagtacga aaaacgtgct aaagatgctg gggtagcaga tgttcatatc
     5821 gtcattgaaa tgggaaatcc aaagaccctg ctagcacgta ctattccaga tgccgaggaa
     5881 gtggacctca tcctcgttgg cgcaactggt ctcaacgcct ttgaacgcct cttggtcggc
     5941 tcttcatctg aatacatact ccgccatgct aaggtcgatt tactggttgt gagagaacaa
     6001 gaaaaaacct tataatcaca aagaaaagga gcccctagct cctttttgtt tacgatttat
     6061 ttctctcttt atggcgttcg taagccttga gctggcgctg cagttccttt ttaatagcag
     6121 gttctggagc atatttttct tcccaattat ctggttttaa gattttatgg gtcactggat
     6181 caaaatgagc cttgccatct ggaaaaattt tccccatatt ggcctgatgg acaatatcaa
     6241 aaatacgttc tgggtccacc cccatcaaga caaaactgcc gtaggtgaag taaagcgtgt
     6301 caatcaaggc atccacttgc cctatcaaat cttgctgagc aggtgtcttc ttggctactt
     6361 tatctgctgc cttatcaagg gcctgatgaa gttgcgatac agcttgacca aaatcttctt
     6421 cagaaggact ggctgctcga acaaactcca ccaattcttc tattttaaaa ccagccctat
     6481 gggttgcacc ctctaaatcc caagctcgag gttcttcttg ggttcgttca tccatcatgt
     6541 ggtggaaggt cttgacctta ttgaaatgat agtcacggct gacaaagact ttttctgaag
     6601 acaaaacacc aaaatgttcc aaggccttgt ggattccatc ttgttgattg ctagtggtaa
     6661 tgtgcttggc agcttccttg acactgctac taccatttcc catagcgacc gacataccga
     6721 cgccagccag catttcaagg tcattatctg agtcaccaaa agccatgact tggttgaggt
     6781 caaagccata ttctttccca actcggcgaa tgccttctaa tttagaattt ccctgattga
     6841 tgacatccga tgcaaaagga ttgctacgtg tcaatttcaa gtcttcaaaa tcagctgccg
     6901 ccttctcaga ttcttctggt gtcatcaaca tcaaaacttg gtagataggc tgattcatca
     6961 ggtgaagcag gtcctcttcc ttttggggaa caaccttgct gaccatgcga ttaaaagact
     7021 gactcaccgt ccgagttaaa acagagggaa cgaagcgact aattcgttgg gaaaaagaac
     7081 ccagaccaaa ggacatgatt ttagaaccca acatggcatc cttggtccct agagcaatct
     7141 ccgtgccctc ttttttagca tagctaatta gatggcgcaa atgtaacttg gaaatagggc
     7201 tcgtgaacaa gactctgtct ttactaaaga tatactggcc attataggtt accgcaaaat
     7261 ccagatccaa atcgtccatc aattccttaa caaaaaaagg tcctcgccct gtcgctacgc
     7321 caactagtac cccttgttct ttgacaatct taatcgcgtc cttagtggat ttcaaaacac
     7381 tcttgcgatt gttgaccaag gttccatcga tatcaaaaaa aacagctttg acttccatcc
     7441 tattccaatc tccccttttg tgatacaatg attataccac atttcagaaa gagttagtaa
     7501 atcatgccta agaaaatcct tgttttacat acgggtggaa ctatttccat gcaggccgat
     7561 gcttctggcg ctgttgtgac gagttcagat aatcccatga accatgtgtc caacccactt
     7621 gaaggaatcc aagtccacgc cttggacttt tttaatcttc caagtcccca tatcaaaccc
     7681 aaacatatgc tggtcctcta ccagaaaatt aaagaggaag cagataacta cgatggagtg
     7741 gtgatcacac acggaaccga tactttagag gaaacagcct atttccttga taccatggaa
     7801 gttccccata tgcctatcgt tctaacagga gccatgcgta gctccaatga gctcggtagt
     7861 gatggtgttt ataattacct aagtgcttta cgagtggcca gcgatgacag ggctgctgac
     7921 aaaggagttt tggtcgttat gaacgatgaa atccacgctg ccaagtatgt caccaaaaca
     7981 catacgacta atgtcagcac cttccagact ccaacacatg gtcccctcgg tctcatcatg
     8041 aaacaggaaa tcctctactt caaaacagct gaacctcgtg ttcgctttga ccttgatcac
     8101 atacaaggtt tagtccctat catctcggct tatgctggta tgacagatga gctgattgat
     8161 atgctggatt tagaacactt ggacggtttg attatccaag ccttcggagc tggtaatatt
     8221 cccaaagaaa cggctcaaaa attagaaagc cttctgcaaa aaggaattcc agtcgctctg
     8281 gtatcacgat gctttaacgg tattgccgag cctgtttatg cctaccaggg tgggggcgta
     8341 cagttgcaaa aagcaggcgt tttctttgtt aaagaactca acgcccaaaa agctcgcttg
     8401 aaactcctca tcgccctcaa tgccggacta acaggacagg ctttgaaaaa ctatatggaa
     8461 ggctaatact cttcgaaaat ctctgcaaac cacgtcacgt cgccttaccg tatgtatggt
     8521 tactgacttc gtcagtttca tccacaacct caaaaacatg ttttgagctg acttcgtcag
     8581 tttcatccac aacctcaaaa acatgttttg agctgacttc gtcagtttca tctgcaacct
     8641 caaagcagtg ctttgagctg acttcgtcag ttctatctac aacctcaaaa acatgttttg
     8701 agctgacttc gtcagttcta tctacaacct caaaacagtg tgttgcgcag cctttaacca
     8761 gccgcctagt ccgctctatg gtattcatta agtcaacatc tcttgtttaa gagcacaaaa
     8821 tcaggaaatc ttctcgattc cctgattttt tctatttacg ttttcgtgtt gagctacgtt
     8881 ctgtcaaacc atgaggtaag agaacttcac gttcttccaa ctcttcctta tgcataatct
     8941 tggtcaacat acgcatacta atggcaccaa ggtcataaag aggttgggca atcgttgtca
     9001 agtttggacg ggtaaagcgt gagatttgtg aatcatcact agtaataatt tcaaaatctt
     9061 ctggcacaga aacaccttta tcagccaaac cgttcaagac tcctgctgcc aactcatcac
     9121 ctgtcacaac tgctgcagtt gcatttgatg aaatcaaacg ctctgctaag gcgtaaccat
     9181 catcatagct atatttagat tcaaatacca aaccctcact ataagtgatt cctgcttttt
     9241 tcaaggtttc cttgtagcca actaaacgaa ccttaccatt gatgtcatcc actagcggac
     9301 cgctaacgaa agcaatacgc tcattttctt tagcaaggta actcactgca tcaattgttg
     9361 cttgcttata gtcaatattg acacttggca actggtgctc aacatcgaca gttcctgcga
     9421 gaacaatcgg agtacgtgaa cgcgaaaatt ctgagcgaat tttatctgtc aagtgataac
     9481 ccatatagat aatgccatct acctgctttg aaaagagggt attgacaaca gaaacttctt
     9541 tctcgttatc ttcatcgcta ttagctagga caatattgta cttgtacatt tctgcaatat
     9601 catcaatccc cttagccaaa ctcgaaaaat aaccattggt aatatttgga atcacgacac
     9661 cgacagtggt tgtcttttta cttgcaagac cacgcgcaac tgcatttgga cgataatcca
     9721 aacgatcaat tacctctagc acttttttac gggtattctc ttttacattt ttattgccat
     9781 tgaccacacg gctgaccgtc gccatggaaa cacctgcttc acgagcgaca tcataaatgg
     9841 ttactgtatc atctgcattc attccttttc ctgtcctttc tatctcacac attcttttac
     9901 aagtagaggt gctgattgaa gctctatatc tacttacaaa agtgaagatg tgaaaatttc
     9961 gttttcatat ttctacttat tccattctat cactaattgt aaacactttc aagtgttttt
    10021 tgaagattga ttgaaaaaat ttcatagaaa acctaggttt agctccttgc taccacctta
    10081 gactaaacaa aaaggaggaa actaagccct cctaaagtta tagtaaaatg aaataagaac
    10141 aggataaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt
    10201 actattctag tttcaatcta ctataggtat tgttccattc actaccgtca attttagcac
    10261 atagtcttca tgaaaatatt atatcatcat aaccaaccag attcttttgc gatattagct
    10321 gcctctgttc gattaccagc atccagtttt gaaagaatat tggtgacata gtttcgaata
    10381 gttccgtttg agaggtaaag ctgatctgcg atttcttggt tggataagcc ccgggcgatt
    10441 ccctttaaga cagcaatctc ttgttctgtc aacggattgg gacgggtcat caccacttcc
    10501 atcaattcag gcgaatactc cttgcgtcct tcgaggacgg tgtgcaaggt ttgcatgagg
    10561 tctgcaatgc ttcgttcctt taatacataa gcatccactc cagccttgac cgcacgttca
    10621 aaatacccag cacgcttgaa ggtcgtcacc acaaccacct ttgtttcaag cttttctgat
    10681 cgtatccact ccaagacttc aagacctgtc ttaacaggca tttctacgtc aaggatggcg
    10741 atatctacag actccttttc taatagttgg attgcttctt gcccattttt ggtttgaagg
    10801 acagactcca catctggttg aagcgtgagc aattgacaca tggcatctcg caacatactt
    10861 tgatcttctg cgactaatac tttcatctta gtttctctcc ttataaggta gtcgaacttg
    10921 cacttccgtt ggatgtttct gactgattac acttacttct cctgaaaatg gaaaaacacg
    10981 atctcggact gtatggagct catctccttt tagaaaagca aagccgcagc catcatcact
    11041 tactgttaaa atgagttcct tctctgtccg ttctaatttt aagtaagctt tagacgcttt
    11101 ggcatgtttg atgatattgg tcaccaactc aagcaaaatc atagaagcca ttgaatccaa
    11161 ttcttgagta aggctagcag tatctagttg gttatctgtt tccacctcaa ttccagcaat
    11221 ttctaacatc tttttcacag tctctagttc ggatgtcaaa gttctagact taagattttc
    11281 cacaatggtt cgaacttcac acattgattc tttgctaatt tgctgtattt ctcttaattc
    11341 cttttccact tgtggataag cctgcatttg aaatagctgc aaggctagat ctgtcttgac
    11401 actaagcata gcaaaggtat gtcccagact atcatgcaaa tcctgaccga tacgattgcg
    11461 ctcattttct gctagcaata gatttatctg ggtattttgc ttgacctgag cttctttcaa
    11521 atcctcgaca aggcgaattc gaaccgagcc caaagtcatc aaatcgacaa aagtaagaat
    11581 tacaagcata tagactagaa actcaacttc gattctctga aaaatcaaaa gtcgccccac
    11641 aacaaggact tgagcaagga gaaatgtcca tacatgtaaa gactttaaac tacgtacgcc
    11701 aaaatgataa attaagagat tggaaaggaa aaagaaaaac cagatataat tcccagcaac
    11761 aaaggcggta ttcccagcta catagaccag catgagcccc cagaaaagcc aagataggcg
    11821 ctggttctta gttattaaaa cacccaaata cgtcactaca aatagaatat caaccaataa
    11881 atgccaagca ggaagctccc caatcactac aggtaggatg ggaaaaagca taaaaatcaa
    11941 actggtccaa aacatatagt gtatgctttt cagtctttca agcattaagc attctcctta
    12001 tgaccttgaa ggtaaatagt caaaccaaat aaaactgctg aaaaaacaag taaataaact
    12061 gtggctgata gattgatgtc accctcgttt aagaaggtct tgagcaactc catcaattga
    12121 taggtcggga gacacttacc aactgcttgc atccagtctg gaaataaaga aatgggcatc
    12181 cagagtccgc ctaaaacagc caatcctaga taaagaagat tgcccacaac agacatcagc
    12241 tgactagttg gtaagagagt caaggtcaag ccaagtgcta caaaagcaat actccccaca
    12301 atcagcaaaa tcgcagctcc aacccatttt actagaggca tgtctacacc tcttacaaaa
    12361 tgtccaactg taaaaacaac cagaattgag accaaataat caaccagcat acttgttatc
    12421 tttgatagat aatattctac catatttaca gggctatgac gcaatgtttt ctgccagttg
    12481 ttcatcttat cggtatgtaa aacagctgga aatgagagga tagttgtcga catcatggaa
    12541 aaggcagtca tggagatgag gtaatcacgc ataaaattcg cgagttcacc tggtgtgtcc
    12601 tgatagatac cagaaaaaaa taaatagaaa gccgtcggca tccctaccga caatagataa
    12661 tagattaatt gtcgtttggt caataaaaat tctatcttac taagtgctat ccatcgtttc
    12721 atcttagtta tctcccttct gcgtctcttc aaagattgta ttcaacaaac tacgattatt
    12781 aacttcgatt tcttgcatcc tacatcctgc ttgggctaat agttcccaga aagcatctgc
    12841 ttctcgagtg actacttgta aagaatcttg ctttagggtc cagttttcaa ccaaatttga
    12901 ctgctctacg acttccttgt aagctatagg aaggataaag tgcttttcta tttcctcgct
    12961 acgcatagct agaggcgtcg tatctcgaat caactctccc ttatttaaga gcaaaatgcg
    13021 gtctgcagtg tgttccactt cctcaatata atgggacgaa tagagaatgg tgactccttg
    13081 cgcttttaac tcctggacaa tttcccaaaa acgttgacga gttgaggtat ccatggacgc
    13141 agtaggctca tctaaaaaaa caatctttgg tcgcccaatt aaggtcaaga cgaaagaaaa
    13201 gagacgcttt tgaccgcctg ataatttttc tgccaactgt tctttttgtt gcttgacaaa
    13261 ctgcaatagt tgatcaattt cctgattgct caaaggattt ggatagatac gttgaaagaa
    13321 agcaatcaac tctttaactt ttaatttctg aacgattaca ttttcttgag ggaggtaagc
    13381 cctagtatag tctaacttag aactcgtcac tggtaaacct tgaatagata cttgaccgct
    13441 tgtgaccagt ttatctccaa gcaaacaatc taagagtgtt gtctttccgg caccatttgg
    13501 accaattaag gcaacacatt caccatcgtt gatttcaaag gagatattcc gcaaaatttc
    13561 cttgtctttt attttcttac tcaatttctc aactttaacc accgtcatga gactctcctt
    13621 tcaaccactc cattcccata aggaaaacga cgaaaatcat aaatccaaac cccaaagcac
    13681 cacgaatgaa ttggcgaagc aaggcttgat caaaccaatc agtaaacatt tccactaacc
    13741 ataccaagag tgacaggccg ataaagaaat agatgatccc tctcttcatt cctcaaactc
    13801 ctttttcaca tctctgacta atttcaaacc ttctctaaca agccaagaca tgattccaaa
    13861 gccagcaaag accttccaag gaaaatggta gaaatcctca tccaatcccg aaaacatgag
    13921 ataggtcata actcctgcta ctactaaact cattgcaata atcattttat ttctcatctc
    13981 ttcttccccc atttcatact acaattatag tcttttaaaa tcagaggagg cagaagcttc
    14041 tgtcactaga aaatatgaca aatgtcataa aaattctgtt caaaacaagc aagatacact
    14101 atacaataaa acacaatcag aaaaatctaa ggcaacttcc tcaaaagaga tatcaaaccc
    14161 aattcacacc ataatgtaaa ctaatactta tttaaaatca aaaagagtag aaatttttat
    14221 cagacaaaca catatatagt gtattgaatc tataacagta ggccttaaat actaaaatat
    14281 ttctataaat t
//
LOCUS       DAVLGK010000051        14241 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLGK010000051 DAVLGK010000000
VERSION     DAVLGK010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14241
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.052"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..251
                     /locus_tag="VXE01_001832"
     CDS             <1..251
                     /locus_tag="VXE01_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0750692.1"
                     /translation="YQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHALSKERSKVENI
                     FAKVKTFKMISTTYRNHRKHFGLRMNLIAGIINHELGF"
     gene            complement(566..2257)
                     /locus_tag="VXE01_001833"
     CDS             complement(566..2257)
                     /locus_tag="VXE01_001833"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV0750693.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNTQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NEDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNNTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2393..2839
                     /gene="argR"
                     /locus_tag="VXE01_001834"
     CDS             2393..2839
                     /gene="argR"
                     /locus_tag="VXE01_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0750694.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2890..5424
                     /gene="mutS"
                     /locus_tag="VXE01_001835"
     CDS             2890..5424
                     /gene="mutS"
                     /locus_tag="VXE01_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV0750695.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTVLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLRYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEHISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5571..7265
                     /gene="patA"
                     /locus_tag="VXE01_001836"
     CDS             5571..7265
                     /gene="patA"
                     /locus_tag="VXE01_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV0750696.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7595..7858)
                     /locus_tag="VXE01_001837"
                     /pseudo
     CDS             complement(7595..7858)
                     /locus_tag="VXE01_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            8056..9822
                     /gene="patB"
                     /locus_tag="VXE01_001838"
     CDS             8056..9822
                     /gene="patB"
                     /locus_tag="VXE01_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV0750697.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVSDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFK"
     gene            9961..10650
                     /locus_tag="VXE01_001839"
     CDS             9961..10650
                     /locus_tag="VXE01_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0750698.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10654..10833
                     /locus_tag="VXE01_001840"
     CDS             10654..10833
                     /locus_tag="VXE01_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750699.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10820..12169
                     /locus_tag="VXE01_001841"
     CDS             10820..12169
                     /locus_tag="VXE01_001841"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV0750700.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12293..13753
                     /locus_tag="VXE01_001842"
     CDS             12293..13753
                     /locus_tag="VXE01_001842"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV0750701.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQIKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13767..14201
                     /locus_tag="VXE01_001843"
     CDS             13767..14201
                     /locus_tag="VXE01_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0750702.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGKERASKFNER"
BASE COUNT         4178 a         2762 c         3196 g         4105 t
ORIGIN      
        1 gttatcaagg gctcatgaag atatatcctc aagcacaaac tccacgtaaa tccagcaaac
       61 tcaagccact aacagttgaa gataaagcct ataaccatgc gctatccaag gagagaagca
      121 aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat gatttcaaca acctatcgaa
      181 atcatcgtaa acacttcgga ttacgaatga atttgattgc tggcattatc aatcatgaac
      241 taggattcta gttttgcagg aagtctatta tttggttagg tgaattagtg aagcgtttag
      301 gcaagtgtct ctggttacga cgtcatggcc tctaaatcga ttatatttag gggtcatgac
      361 tagtgaagca gttagctagt tcgcatataa gcggctagcg tctaacaatt aggaacttta
      421 gttccaataa ctttaagatt acgacgtttt aggacataaa tcgatcatat ttatgtccta
      481 aaactagtga agcgcctagc caaagtccga ataggatttg gcgttagtta cttagattgc
      541 tttgcaatca agtaactttg gcgatttaca tcttctctgg cgcttctact ccaagcaagc
      601 gaagggcttc tttgagaacg actgcggttg cgtagctgag ggctagacgg ctgtcgcgtt
      661 ctgggctttc atccaagata cgtgtatgtg catagtattt gttaaaggat tgagccaggc
      721 taattgcaaa tttagcaatg atagaaggtt caaagttatc tgccgcacgg ttgataatac
      781 gtgggaagtc ttgaatgagt ttaatgattt cccagctttc agtattattc aagctatagt
      841 tgccagctgt ttctggtttg aaatcggctt tgcgtaagat agattggata cgagcgtagg
      901 catattgaac gtaaggtcca gtttcaccct cgaaggatac catagcctct aggtcgaagt
      961 cgtatccatt tgtacggtcg gttttgaggt catagaattt aatggctcca accccaacag
     1021 catgtgctac ctgatcttta ttttccaatt caggattttt agcctcgatt tggaccttgg
     1081 cacggctaac agcctctgca acagtaggct ctagcaagat gacattccct ttacgagtag
     1141 agagcttctt cccttctttt gtaaccaagc caaaaggaac gtgagtaatg tcgtcactcc
     1201 agtcgtagcc catctcttgc aagacagctt tgagctgttt aaagtgggca gattgttctt
     1261 gaccaacgac atagatagat ttagcaaatt ggtattcgtt tttacggtaa agggctgcag
     1321 ccaagtcacg tgtgatatag agagttgcac catcagactt cttgatgagg gctggatgtt
     1381 caattccgta tttctcaaga ttcacaactt gggcaccttc tgattcaaga agtagtcctt
     1441 tttcagaaag aatgtctaca actgcatcca tcttatcatt gtagaaggct tctccgttat
     1501 agctgtcaaa ttcaaccttc aattcattgt aaaggcggtt aaattccact aaactttcat
     1561 cgcggaacca ttgccaaaga gcgagagctt cctcatcttc attttcaagt ttacggaacc
     1621 attcgcgcgc ttcttcatcc aagctagggt cattttcagc ttcagcgttg atgcggacat
     1681 agagtttaag gagttcatcg attggatgag cttttacagc ttcttcgtcg ccccattttt
     1741 tgtaggcaac aatcaacatc ccaaattgtt taccccagtc tcccaaatgg ttgaccttga
     1801 ccgtttgata accgattttt tggaaaatat gtgacaagct atctccgata acagttgaac
     1861 gcaggtggcc aatagaaaat ggtttagcga tattcggact agacatgtcg ataacaacat
     1921 tttcttgttt gccaatattt tggtcagcat agtgttcttt ttcagtggta acagcttgca
     1981 atacttgagc agaaatggca gatttatcaa ggaaaaagtt aacgtaaggt cctgttgcga
     2041 caactttttc aaaggcttgg gtgttcattt tttcagccag ttcagccgca atcatttgtg
     2101 gtgctttacg ttcgactttg gcaagagaaa aagcagggaa agcgatgtca cccatttctg
     2161 agtttttagg ggtttccagt aactttaaaa tagcctcttg gtccaggcta tcaatgatgc
     2221 tagccaattc gctagcaatc aattcttttg tattcattaa gagctccttt ttggactttt
     2281 ctactatttt atcacaattt taaagaaaga agaaaaaatt tttgaaatct cctgtttttt
     2341 tggtataata tggttataaa tatagttata aatatacacg caagaggatt ttatgagaaa
     2401 aagagatcgt catcagttaa taaaaaaaat gattactgag gagaaattaa gtacacaaaa
     2461 agaaattcaa gatcggttgg aggcgcacaa tgtttgtgtg acgcagacaa ccttgtctcg
     2521 tgatttgcgc gaaatcggct tgaccaaggt caagaaaaat gatatggtgt attatgtact
     2581 agtaaatgag acagaaaaga ttgatttggt ggaatttttg tctcatcatt tagaaggtgt
     2641 tgcaagagca gagtttacct tggtgcttca taccaaattg ggagaagcct ctgttttggc
     2701 aaatattgta gatgtaaaca aggatgaatg gattttagga acagttgctg gtgccaatac
     2761 cttattggtt atttgtcgag atcagcacgt tgccaaactc atggaagatc gtttgctaga
     2821 tttgatgaaa gataagtaag gtcttgggag ttgctctcaa gacttatttt tgaaaaggag
     2881 agacagaaaa tggcgataga aaagctatca cccggcatgc aacagtatgt ggatattaaa
     2941 aagcaatatc cagatgcttt tttgctcttt cggatgggtg atttttatga attattttat
     3001 gaggatgcgg tcaatgctgc gcagattctg gaaatttcct taacgagtcg caacaagaat
     3061 gccgacaatc cgatccctat ggcgggtgtt ccctatcatt ctgcccaaca gtatatcgat
     3121 gtcttgattg agcagggtta taaggtggct atcgcagagc agatggaaga tcctaaacaa
     3181 gcagttgggg ttgttaaacg agaggttgtt caggtcatta cgccagggac agtggtcgat
     3241 agcagtaagc cggacagtca gaataatttt ttggtttcca tagaccgcga aggcaatcaa
     3301 tttggcctag cttatatgga tttggtgacg ggtgactttt atgtgacagt tcttttggat
     3361 ttcacgctgg tttgtgggga aatccgtaac ctcaaggctc gagaagtggt gttgggttat
     3421 gacttgtctg aggaagaaga acaaatcctc agccgccaga tgaatctggt actctcttat
     3481 gaaaaagaaa gctttgaaga ccttcattta ttggatttgc gattggcaac ggtggagcaa
     3541 acggcatcta gtaagctgct ccggtatgtt catcggactc agatgaggga attgaaccac
     3601 ctcaaacctg ttatccgcta cgaaattaag gatttcttgc agatggatta tgcgaccaag
     3661 gctagtctgg atttggttga gaatgctcgc tcaggtaaga aacaaggcag tcttttctgg
     3721 cttttggatg aaaccaaaac ggctatgggg atgcgtctct tgcgttcttg gattcatcgc
     3781 cccttgattg ataaggaacg aatcgtccaa cgtcaagaag tagtgcaggt ctttctcgac
     3841 catttctttg agcgtagtga cttgacagac agtctcaagg gtgtttatga cattgagcgc
     3901 ttggctagtc gtgtttcttt tggcaaaacc aatccaaagg atctcttgca gttggcgact
     3961 accttgtcta gtgtgccacg gattcgtgcg attttagaag ggatggagca acctgctcta
     4021 gcctatctca tcgcacaact ggatgcaatc cctgagttgg agagtttgat tagcgcagcg
     4081 attgctcctg aagctcctca tgtgattaca gatgggggaa ttatccggac tggatttgat
     4141 gagactttag acaagtatcg ttgcgttctc agagaaggga ctagctggat tgctgagatt
     4201 gaggctaagg agcgagaaaa ctctggtatc agcacgctca agattgacta caataaaaag
     4261 gatggctact attttcatgt gaccaattcg caactaggaa atgtgccagc ccactttttc
     4321 cgcaaggcga cgctgaaaaa ctcagaacgc tttggaaccg aagaattagc ccgtatcgag
     4381 ggagatatgc ttgaggcgcg tgagaagtca gccaacctcg aatacgaaat atttatgcgc
     4441 attcgtgaag aggtcggcaa gtacatccag cgtttacaag ctctagccca aggaattgcg
     4501 acggttgatg tcttacagag tctggcggtt gtggctgaaa cccagcattt gattcgacct
     4561 gagtttggtg acgattcaca aattgatatc cggaaagggc gccatgctgt cgttgaaaag
     4621 gttatggggg ctcagaccta tattccaaat acgattcaga tggcagaaga taccagtatt
     4681 caactgatta cagggccaaa catgagtggg aagtctacct atatgcgtca gttagccatg
     4741 acggcggtta tggcccagct gggttcctat gttcctgctg aaagcgccca tttaccgatt
     4801 tttgatgcga tttttacccg tatcggagca gcagatgact tggtttcggg tcagtcgacc
     4861 tttatggtgg agatgatgga ggccaataat gccatttcgc atgcgaccaa gaactctctc
     4921 attctctttg atgaattggg acgtggaact gcaacttatg acgggatggc tcttgctcag
     4981 tccatcatcg aatatatcca tgagcacatc ggagctaaga ccctctttgc gacccactac
     5041 catgagttga ctagtctgga gtctagttta caacacttgg tcaatgtcca cgtggcaact
     5101 ctggagcagg atgggcaggt taccttcctt cacaagattg aaccgggacc agctgataaa
     5161 tcctacggta tccatgttgc caagattgct ggcttgccag cagacctttt agcaagggcg
     5221 gataagattt tgactcagct agagaatcaa ggaacagaga gtcctcctcc catgagacaa
     5281 actagtgctg tcactgaaca tatttcactc tttgataggg cagaagagca tcctatccta
     5341 gcagaattag ctaaactgga tgtgtataat atgacaccta tgcaggttat gaatgtctta
     5401 gtagagttaa aacagaaact ataaaaccaa gactcactag ttaatctagc tgtatcaagg
     5461 agacttcttt gacaattctc cacttttttg ctagaataac atcacacaaa cagaatgaaa
     5521 aggagctgac gcattgtcgc tcccttttgt ctatttttta aggagaaagt atgctgattc
     5581 agaaaataaa aacctacaag tggcaggccc tggcttcgct cctgatgaca ggcttgatgg
     5641 ttgctagttc acttctgcaa ccgcgttatc tgcaggaagt cttaggcgcc ctccttactg
     5701 ggaaatatga agctatttat agtatcgggg cttggttgat tggtgtggcc gtagtcggtc
     5761 tagttgctgg tggactcaat gttgtcctcg cagcctatat tgcccaagga gtttcatccg
     5821 accttcggga ggatgccttc cgtaaaattc aaaccttttc ttatgctgat attgaacaat
     5881 ttaatgcggg aaatctagtc gttcgaatga caaatgatat caaccagatt cagaacgttg
     5941 tcatgatgac cttccaaatt cttttcagac ttcccctctt gttcatcggt tcgtttatcc
     6001 tagcggttca aaccttacct tctctgtggt gggtgattgt tctcatggta gtcttgattt
     6061 ttggtttgac tgctgtcatg atgggaatga tggggcctcg ttttgccaag tttcaaaccc
     6121 ttcttgagcg catcaatgcc attgccaagg aaaatttacg tggcgttcgt gtggtcaagt
     6181 cctttgtcca agaaaaagag caatttgcta agtttacaga ggtctcagac gagcttcttg
     6241 gtcaaaacct ttacattggt tatgcctttt cagtagtgga accctttatg atgttggttg
     6301 gttacggggc ggtcttcctc tctatttggc tggtcgcggg aatggttcag tcggatccgt
     6361 ctgttgttgg ttccatcgct tcttttgtta attacctaag ccagattatc tttaccattg
     6421 ttatggttgg atttttggga aattctgtca gccgtgccat gatttccatg cgtcgtattc
     6481 gagaaattct tgacgcagag ccagctatga ccttcaagga tatcccagat gaagagttgg
     6541 ttggaagtct tagctttgaa aatgtgacct ttacctatcc aatggacaag gaaccgatgc
     6601 tgaaagatgt gagctttact attgaacctg gtcaaatggt tggtgtagtt ggagcgactg
     6661 gtgcaggaaa gtcaaccttg gctcaattga ttccacgtct ctttgatcca caggacgggg
     6721 ccattaaaat cggtggcaag gatattcgag aagtgagtga aggaaccctg cgtaaaacag
     6781 tttccatcgt tctccaacgt gccattcttt ttagtggaac gattgcagat aacttgagac
     6841 aggggaaggg gaatgctact ctatttgaaa tggagcgcgc agccaatatt gcccaggcta
     6901 gtgaattcat tcatcgtatg gagaaaacct ttgaaagtcc agttgaagaa cggggaacca
     6961 atttctctgg tggacaaaaa caaaggatgt cgattgcgcg tgggattgtc agcaatccac
     7021 gtattctgat ttttgatgat tcgacctcag ccttggatgc caaatcagag cgcttggtgc
     7081 aagaagcttt gaataaggac ttgaagggga cgacaaccat tattattgct caaaaaatta
     7141 gctcggttgt ccatgcagac aagatcttgg ttctaaatca aggacgattg attggtcaag
     7201 gcacgcatgc agacttggtt gccaacaatg ccgtttaccg tgaaatctat gaaacacaga
     7261 aatgaaagac aaactataag aaaagtcaat agttttatct aaactatttc ttatttcaat
     7321 ttgatgattt ggcgatgatt ttagagcacg gcaaaaagct attgaaaaag tccatttttt
     7381 caaaggtaat cctgtgttaa tttcagaaat tatatcactt tttgttcgtc aaatggcagc
     7441 tcttttttag gatataaaac agggttcgga taagtttttt tgcaaggtgg atgatggcta
     7501 cattgtaatg ttttccttgt tctaatttag tcttaagata ggccttaaaa gcaggcgaaa
     7561 agcgagggca tgctttggca gcttgtatga gtacctaccg cagatgaggg gaactccgtt
     7621 tgaccattct tcctgctaaa tcaatctgat ctgactgata aatagaagaa tccagtccag
     7681 cgaaagcttg taattgagca ggattatcaa aggcatgaat atttcgaatc tcagctaaaa
     7741 tgaccgcccc taaacgatcc ccaatcccag taaccgtcgt gatgaccgag ttgaactcag
     7801 ccatcaagtc attgacacat gtttccgcct tgtcaatgag cctcttgtaa tgtttgatgt
     7861 tttcattaca cgagataaaa cgtctatgcg ttatcaaact cattaccaat taaaacaaaa
     7921 agctgtggtt agatcctttc ggaaattgtc aagcgattgg aggaaatgaa ctaatccaca
     7981 gcggcttatt ccaagtatac cacttgggct ttggcagtag ctaactgcgc taaatataat
     8041 ataaggagga gtaaaatgaa gacagttcaa tttttttggc attattttaa ggtctacaag
     8101 ttctcatttg tagttgtcat cctgatgatt gttctggcga cttttgccca agccctcttt
     8161 ccagtctttt ctggacaagc ggtgacgcag ctagccaatt tagttcaagc ttatcaaaat
     8221 ggcaatccag aacttgtatg gcaaagccta tcaggaatca tggtcaatct tggcctgctg
     8281 gttttggttc tatttatctc tagtgtaata tacatgtgtc tcatgacgcg cgtgattgca
     8341 gaatcgacca acgagatgcg caaaggcctc tttggtaagc ttgctcagtt gacggtttct
     8401 ttctttgacc gtcgacaaga tggcgatatc ctgtctcatt ttaccagtga tttggataat
     8461 atcctccaag cctttaacga aagcttgatt caggtcatga gcaatattgt tttatacatt
     8521 ggtctgattc ttgtcatgtt ttcgagaaat gtgacgctgg ctctcatcac cattgccagc
     8581 accccattgg ctttccttat gctgattttc atcgtgaaaa tggcacgcaa atacaccaac
     8641 ctccagcaga aagaggtagg gaagctcaac gcctatatgg atgagagcat ctcaggccaa
     8701 aaagccgtga ttgtgcaagg aattcaagag gatatgatgg caggatttct tgaacaaaat
     8761 gagcgcgtgc gcaaggcaac ctttaaagga agaatgttct caggaattct tttccctgtc
     8821 atgaatggga tgagcctgat taatacagcc atcgtcatct ttgctggttc ggctgtactt
     8881 ttgaatgata agtctattga aacaagtaca gccctaggtt tgattgttat gtttgcacaa
     8941 ttttcacagc agtactacca gcctattatc caagttgcag cgagttgggg aagccttcag
     9001 ttggccttta ctggagctga acgaattcag gaaatgtttg atgcagagga ggaaatccga
     9061 cctgaaaagg ctccaacctt cactaagttg caagaaagtg ttgaaatcag tcatatcgat
     9121 ttttcatact tgcctgataa acctattttg aaagatgtca gcatttctgc ccctaaaggc
     9181 cagatgacag cagttgttgg gccgacaggt tcaggaaaaa cgactattat gaacctcatc
     9241 aatcgctttt atgatgttga tgctggtggt atttattttg atggtaaaga cattcgtggc
     9301 tatgacttag atagtcttag aagcaaggtg ggaattgtat tgcaagattc ggtcttgttt
     9361 agcggaacga ttagagacaa tatccgattt ggtgtgtcag atgctagtca ggaaatggtt
     9421 gaggtagcag caaaagcaac ccacattcac gactatatcg aaagtttgcc tgataagtac
     9481 gatactctta ttgatgatga ccagagcatc ttttcaacag ggcagaagca attgatttca
     9541 atcgctcgaa ccctgatgac agatccagaa gttctcattc tcgatgaagc aacttcaaac
     9601 gtagatacgg tgacagaaag caagattcag catgccatgg aggtggttgt agcaggtaga
     9661 actagtttcg tcattgccca ccgcttgaaa accattctca atgcagatca gattattgtc
     9721 cttaaagatg gagaagtcat tgaacgtggt aaccaccatg aacttttgaa gctaggtggc
     9781 ttttattcag aactctatca caatcaattt gttttcaaat aagaaagaag ttgtcctatg
     9841 tgggcagctt tttcttgtcc ataaaaaatg tttatcacag ccttaaaaaa aacatattag
     9901 acgaaagtca ttttgagtga tatgatagga ctatcgttag cattcgaaag gagaggcatc
     9961 atggctagaa cggttgtagg agttgctgca aatctatgtc ccgtagacgc agaaggcaaa
    10021 atcattcatt catctgtatc ttgtagattc gcagagatca ttcgtcaagt cggtggtctc
    10081 cctttagtca ttcctgttgg tgatgagtca gttgtacgtg attatgtgga aatgattgac
    10141 aaactcattt tgacaggagg ccaaaatgtt catcctcagt tttatggaga gaaaaagacc
    10201 gtcgaaagcg atgattacaa tctggtccgt gacgaatttg aattggcact cttgaaggaa
    10261 gcgcttcgtc agaataaacc aattatggca atctgtcgcg gtgtccaact tgtcaatgtt
    10321 gcctttggtg gaaccctcaa tcaagaaatc gaaggtcact ggcaaggact acctttcggg
    10381 acatctcact ctattgagac agtagaagga agcgtggtgg ctaagctatt tgggaaagaa
    10441 agtcaggtca actcagtcca tcgtcaaagc attaaagatt tggcacctaa tttccgtgta
    10501 actgctattg attcaagaga ccaaactatt gaagcgattg agtctatcga cgagcaccgc
    10561 attatcggtt tacagtggca tccagagttt ctggttaatg aagaagatgg caatttagaa
    10621 ttatttgagt atttattgaa tgaactgtaa cgattggaac atctggtcgt tctttctttt
    10681 attttttcaa aatttttaga atgtggcatt ttacgcaaac gtttgaattc tgataaaaat
    10741 tggagaaatt cgacaaaaaa acttgaaaaa aacgaaggta agcgttatga tagaaaagaa
    10801 gaaatattgg aggaagaaca tgtcacatat taaatttgat tattcaaaag ttttagacaa
    10861 atttgttgca ccacatgaag tggaatacat gcaatcacaa gtaacagcag cagatgaatt
    10921 gatccgtaaa ggaactggtg ctggtagcga cttcttggga tggttggacc ttcctgaaaa
    10981 atacgatcgc gaagaatttg accgcatctt gaaagctgct gagcaaatca agtcagacag
    11041 cgatgttttg gttgtgatcg gtattggtgg atcttacctt ggtgcaaaag cagcaatcga
    11101 cttcttgaat caccattttg ctaacttgca aacaaaagaa gaacgcaaag ctccacaaat
    11161 cctttacgca ggaaactcaa tctcatctac ttaccttgct gacttggtag agtatgttgc
    11221 agacaaagac ttctcagtaa acgtaatttc taaatcaggt acaacaactg aaccagcgat
    11281 tgctttccgt gtctttaaag aactcttggt taagaaatac ggtcaagaag aagctaacaa
    11341 acgtatctat gcaacaactg accgccaaaa gggtgctgtt aaggttgaag cagatgctaa
    11401 cggttgggga acatttgttg ttccagatga tatcggtgga cgcttctcag tattgacagc
    11461 cgttggtttg cttccaatcg cagcatcagg agctgacatc aaagctctta tggaaggtgc
    11521 gaatgcagct cgcaaagact acacttcaga caaaatctct gaaaacgaag cttaccaata
    11581 cgcagctgtt cgtaacatcc tttatcgtaa aggctatgca actgagatct tggtaaacta
    11641 tgagccatca cttcaatact tctcagaatg gtggaaacaa ttggctggtg aatcagaagg
    11701 aaaagaccaa aaaggtatct acccaacttc agccaacttc tcaactgact tgcactcact
    11761 tggtcaattt atccaagaag gaactcgtat catgtttgaa acagttgtcc gtgttgacaa
    11821 acctcgtaaa aacgtgctta ttcctacttt ggaagaagac cttgacggac ttggttacct
    11881 tcaaggaaaa gacgttgact ttgtaaacaa aaaagcaact gacggtgttc ttcttgccca
    11941 cacagatggt gatgtaccaa acatgtatgt gactcttcca gagcaagacg ctttcactct
    12001 tggttacact atctacttct tcgaattggc aattgccctt tcaggttact tgaatgctat
    12061 caacccattt gaccaaccag gtgttgaagc ttataaacgt aacatgtttg cccttcttgg
    12121 aaaaccagga tttgaagaat tgagcaaaga acttaacgca cgtctataat agaagaaaag
    12181 agtggtttgc ccactctttt tactctcttt atccatagaa attggactca gccaagactt
    12241 gtgatataat atagaaagca aaaaggcaga cgcctagata ataggagaaa ctatgtcaaa
    12301 agatatccgc gtacgttacg caccaagtcc aacaggacta ctacacatcg gaaatgctcg
    12361 tacagcattg tttaattact tgtatgcgcg ccatcatggt ggaacatttc tcatccgtat
    12421 cgaagatact gaccgtaaac gccatgtcga ggatggtgaa cgttcacaac ttgaaaacct
    12481 tcgctggtta ggcatggatt gggatgaaag tccagaatca catgagaatt atcgccagtc
    12541 tgagcgtttg gacttgtatc aaaaatacat tgaccaacta ttagctgaag gaaaagccta
    12601 taaatcttac gttacagaag aagagttggc agctgaacgc gaacgccaag aagtagctgg
    12661 cgaaacacca cgctacatca atgaatacct tggtatgagt gaagaagaaa aagcagctta
    12721 catcgcagaa cgtgaagcag cagggatcat cccaactgtt cgtttggctg tcaatgagtc
    12781 aggtatctac aagtggcatg atatggtcaa aggcgatatc gaatttgaag gtggcaatat
    12841 cggtggtgac tggattatcc aaaagaaaga cggttaccca acttacaact ttgccgttgc
    12901 catcgatgac cacgatatgc aaatctctca tgttatccgt ggagatgacc atattgctaa
    12961 tacaccaaaa cagcttatgg tctatgaagc tcttggttgg gaagctccag agttcggtca
    13021 catgaccttg attatcaact ctgagactgg taagaagtta tctaaacgtg atactaatac
    13081 acttcaattt atcgaagatt accgaaagaa aggttacctt ccagaagcag tctttaactt
    13141 tattgctctt cttggttgga acccaggtgg tgaagatgag attttctctc gtgaagaact
    13201 cattaaactt tttgatgaaa accgcctcag caagtcacca gcagcctttg atcagaaaaa
    13261 actagactgg atgagcaatg attatatcaa gaatgcagac cttgaaacca tctttgaaat
    13321 ggcaaaacca ttcttagagg aagcaggccg tttgactgac aaggctgaaa aattagttga
    13381 gctctataaa ccacaaataa aatcagtaga tgagattatc ccattgacag atcttttctt
    13441 ctcagatttc ccagaattga cagaagcaga gcgcgaagtc atgacgggtg aaacagttcc
    13501 aacagttctt gaagcattca aagcaaaact tgaagcgatg acagatgata aatttgtgac
    13561 agaaaatatc ttcccacaaa ttaaagcagt ccaaaaagaa acaggtatta aagggaaaaa
    13621 tcttttcatg cctattcgta tcgcagtttc aggcgaaatg catgggccag aattaccaga
    13681 tacaattttc ttgcttggac gtgaaaaatc aattcagcat atcgaaaaca tgctaaaaga
    13741 aatctctaaa taaagaggat acaataatgg acatctggga aaagatgtac gaagaagcac
    13801 agaaactata caatccacat gaagtatcag actttgttta tgccaatcat gttgtagctg
    13861 cagtagaagc agaagatgga caaatattta caggattctg tatggaggga acctgtggtg
    13921 ttttccatct ctgcgcagaa cgggcggccc tcttcaatat gtaccaattt tcaggacaaa
    13981 ctaaggttaa gaaagtatta gcctttcgag acaaaccacc ttatggtgga agttcagcca
    14041 tgccttgcgg tgcttgtaga gaattccttt tagagcttaa tgctgaaaat aaagatgcag
    14101 aattcatgat ggactataat ataagaaaaa cagttaaagt cgcagaacta atcccttatt
    14161 ggtggggaaa agaacgtgct tctaagttta atgagcgata gaagagtcag tataattctg
    14221 gctcttttta ctataagttg c
//
LOCUS       DAVLGK010000052        14189 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLGK010000052 DAVLGK010000000
VERSION     DAVLGK010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14189
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.053"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(2..1852)
                     /locus_tag="VXE01_001844"
     CDS             complement(2..1852)
                     /locus_tag="VXE01_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0750703.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIILLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(1894..3051)
                     /locus_tag="VXE01_001845"
     CDS             complement(1894..3051)
                     /locus_tag="VXE01_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0750704.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            3109..4192
                     /locus_tag="VXE01_001846"
                     /pseudo
     CDS             3109..4192
                     /locus_tag="VXE01_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
     gene            4331..4657
                     /locus_tag="VXE01_001847"
     CDS             4331..4657
                     /locus_tag="VXE01_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0750705.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            4644..5237
                     /locus_tag="VXE01_001848"
     CDS             4644..5237
                     /locus_tag="VXE01_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV0750706.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            5230..6141
                     /locus_tag="VXE01_001849"
     CDS             5230..6141
                     /locus_tag="VXE01_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV0750707.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6204..7268
                     /locus_tag="VXE01_001850"
     CDS             6204..7268
                     /locus_tag="VXE01_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750708.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADFDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIEAPEDSEARTGIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKFETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(7446..8306)
                     /locus_tag="VXE01_001851"
     CDS             complement(7446..8306)
                     /locus_tag="VXE01_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV0750709.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(8581..9567)
                     /locus_tag="VXE01_001852"
     CDS             complement(8581..9567)
                     /locus_tag="VXE01_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV0750710.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(9839..11314)
                     /locus_tag="VXE01_001853"
     CDS             complement(9839..11314)
                     /locus_tag="VXE01_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0750711.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     IWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEVLNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(11572..12495)
                     /locus_tag="VXE01_001854"
     CDS             complement(11572..12495)
                     /locus_tag="VXE01_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0750712.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(12509..13438)
                     /locus_tag="VXE01_001855"
     CDS             complement(12509..13438)
                     /locus_tag="VXE01_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0750713.1"
                     /translation="MNKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
BASE COUNT         4266 a         3047 c         2612 g         4264 t
ORIGIN      
        1 tttattcaat gtgggttgtt tgattagcaa aggcgataat agcttgcttc aactcatctc
       61 cactgagagt gcggaactct ccaatctttt gattgatgga ttctaaaggc atgacattaa
      121 ccttaccaac gaaaatctta tccataactt gattgtcaac gagttcggtt gataccaaga
      181 gttcttcgta gagtttttca cctgggcgga ttccaacttc aacgattgga atttcacttt
      241 cagtgtggcc acttagaagc accatcttct tggccaagtc ataaatcttg actggtttgc
      301 ccatatcaag gataaagact tccccatctt tggcataagc accagcatgg ataaccagac
      361 ggctagcttc tggaatggtc ataaagtaac gggtcatgcg gaagtctgtc accgttacag
      421 gcccaccttc agcaatctga cgttcaaaga ctggaatgac actaccacgg ctaccaagaa
      481 cattcccaaa acgaactgca cagtaggttg attggctacg ttggttaaag ccagtgacaa
      541 tcaactccgc cacgcgcttg gttgctccca taacatttgg tggattgact gccttatctg
      601 tcgaaatcat aaccatctta gacactttag cttcatcaac agccttagca acattgtaag
      661 ttccacggat attgtttttg aaggcttctt ttggattgcg ctccatcata ggaacatgct
      721 tgtgggctgc cgcatgataa acaatagcag gtttgtactg ctcaaagact tgcaacaaac
      781 gatcatagtc ttgaatgtcc gcaatcacag gtacataatc aatcccttgg aacttacgaa
      841 tcaattcatg ataaacaagg tagattgagt tttccccatg accgagcaag ataatgcgtt
      901 caggattgaa gcgactaact tgacgacaga tttcagaacc gattgaacct ccagctcctg
      961 tgactaagat ggtcttacct gtcagttctg cacccagacg cgattcgtca agacggattt
     1021 cctgacgacc caaaaggtcc gtaatatcaa ttttttggaa gccagtacct gcttggtgaa
     1081 ggccctgaac aacagtttca accttaggca tcttgtaaca tttgacaccc agcttattac
     1141 acatctgcaa gatacgctca tattctgacg gatccagcga cggaatcgca acgatgacac
     1201 gctcgatttg atggcgtttg gctaattcag gcagattgtc ataagagccc aaaacaggaa
     1261 taccaccaag tttttgaccc tttttcttag aatccttatc caaaataccg accagttcta
     1321 attcactggt tggatgttgg taactatcca taaaaagagc cccaccatca ccggcaccaa
     1381 tcaagaaggt ccgacggtgt tctccatcac cactaccttt tttgcgtctg gagtagatta
     1441 actgccaagt aatccgtggc aataaaatca agaaggtact caacaagata aagagaatga
     1501 tgaaacggat ggagaagagt ggcaagaagg cataacagat actatatgac aagacactgc
     1561 tagcagtcac accaaaaaag attttcatga aatccgtaat cttgctgtaa cgactaatgc
     1621 tcgcgttcaa cccccaaaaa ccaatcatca attgatagaa caggaaggcc aaactcgtat
     1681 agataatgta gtcaacaggt gctggattaa tcagcccata aaataaaata taagatacaa
     1741 tgatggaaac caccatactg aaaatatcaa atattcccca gaaaacctgc ttttgttgtt
     1801 tatttaaaat ttccaccaga tcaatcacat aatctgttag ttttttattc atagaaatct
     1861 actcctcctt aaaagagttt tactatattg ttattatagc atattttgat ttatttggct
     1921 tattttatcc aaataaatta ttgttccctt gtactccttc ttccatttaa atcctctaat
     1981 taaacctaca atcgtcccaa agccataagc aaagtgaatg gaaaataaaa gaaagggcat
     2041 cacaattaga aatccatttt tatgttttaa taaagtcagc aaagtgagta gtgacaaaag
     2101 tagaaaatag gcacctaata gtaaagttat gaatacgaat gtgatcggta acaatgctag
     2161 actaaacaca agactcaaaa caaataaaca aggaacatag tgaaataatg ataaacactt
     2221 aaactgaaca tgacttgtca agccaatcca caaaccattt gaatactttt gatgcagcat
     2281 tttcttgaat gttggtcgaa tatactgata agatagaata cttgggctat agcggatttt
     2341 ataaccatgt tctcgaattc tataatgaat atcattatct tcagttcggc caagttgctc
     2401 atttactaaa ccaaccttct ggaaaacctc tcgtttatac atcccatgaa aaatagaaga
     2461 aacatatcta tcctcggaac tatttcgata attggcaata ctacttccaa acatattttc
     2521 ctcaacaaga tgcaaggtct ctgcccattt tccttttcct tcgacaatcg tcggtctagg
     2581 ccccccacag acaaattcac cttgttgaat aatagccaca ttgttcatta caaaactctc
     2641 agtaactttt gaatgagcat caatttttaa aataaggtcc cctacagaat gtttaactcc
     2701 caggttaaaa ccactagctt gatttttctt aggattgtta tacaatctaa ttgagttaaa
     2761 ctctgtatct tcctttataa attgctgaat gatagctgtg gtcccatctg tggacatagc
     2821 atttataaat agaatttcaa tattctcttt aggataggtt tgatttttta agtcttcaat
     2881 tagaccaggc agatattttt cttcattgta tgcactgatt acaatggata cgagaagact
     2941 ttcaacattt tgagtcacta ctactctcct gaatttttcc ttccaccatt ctatcataat
     3001 tttcaagact ttcccatttt tatcttgaaa gccagaaacc ttacttgaca ttatagtgaa
     3061 aaagccttaa aataagctgt tattaaaatc agctagaaga ggtattatat gaaaaagcaa
     3121 tcactctttt ttgttccagg tattatcctg attggtgttt ccttgcgaac tccttttact
     3181 gttttaccca ttattttggg aaatatttcg caaggtctgg aggtagaagt tagttcgctt
     3241 ggtgtcttga ccagcctgcc tcttcttctt gaccatcggc tcacttattc gactaatcaa
     3301 tctgcccctg ctctatctag gaaccttgat ggttggggca agtgtcgcag tcatcaatgt
     3361 cctgcttcct agtcttatcc aagccaatca accaaagaaa attggttttc tgaccacctt
     3421 atatgtaacg tctatgggga ttgcaacggc tctggcttcc tatctagctg tgcccattac
     3481 acaagccagt tcttggaaag gacttatcct tctcctcacg ttactctgtc tagcaacttt
     3541 tttggtctgg ctcccaaatc accgctataa tcatagacta gctccacaaa ccaaacaaaa
     3601 aagtcaaata aaggtcatgc gtaataaaca ggtttgggca attattatct tttcaggttt
     3661 tcaatccttg atcttttaca ccgtcatgac ctggttacct accatgtcta tccatgcagg
     3721 tctatccagt cacgaagctg gcttgctgac ttctatctta tctctgatta gcattccttt
     3781 ttcaatgacc atcccaagcc tgacaaccag tttatctact cgcaaccgtc agctcatgct
     3841 cactctggtt tcactagctg gtgtggtcgg catttccatg ctctttttcc caatcaataa
     3901 tttcatttac tggcttgcca tccatctcct catcggaacc gcaaccagtg ccctcttccc
     3961 ttatctcatg gtcaactttt cactcaagac aagcgcccct gaaaagacag cccaattgtc
     4021 cggcctatct caaacaggag gctatatcct agcagccttt gggccaaccc tctttggtta
     4081 cagttttgac ctgttccact cttgggtacc atctgtagct gccctcttgc tcatcgatat
     4141 cctgatgact gtggccctct ttacagtgga cagagcggat aagatccttt aaacttctag
     4201 ttttagctag aagtttttta tatataaaaa ttttacacat ttctcttgac agggctttct
     4261 tttagatgta caatgtatgt gtagaaaaat tatatataaa aatcttacac attagaaaag
     4321 gaggtttccc atgtactttc caacatcctc tgccttgatt gaatttctca tcttggccgt
     4381 actggagcag ggtgattctt atggttatga gattagccaa accattaagc tgatcgctaa
     4441 tatcaaagaa tctacactct atcccattct caaaaaattg gaaggcaata gctttctgac
     4501 aacctattct agagagttcc aaggtcgcat gcgcaaatac tactccttga caaacggtgg
     4561 tatagagcag ctcttgaccc taaaagatga atgggcactc tatacagaca ccatcaatgg
     4621 catcatagaa gggagtatcc gccatgacaa gaactgaata cctgactcag ctagaactct
     4681 atctcaagaa actacctgaa gctgaccgta tcgaagccat ggactatttc agagagctct
     4741 ttgacgatgc tggagtcgaa ggagaagaag aactcatcgc tagtttggga actcccaaag
     4801 aagcggccca cgaagttcta tccaatcttc tcgataaaaa aatcaatgaa gcacccgctc
     4861 aaaaaaataa ccgacaaatt ttacatatcg ccttgttagc cctccttgca gcacctatcg
     4921 gcattcctct gggaatcgcc atcctcgtga ccctgttcgc aatccttgta gccgctttga
     4981 ctgtcattct ggctttcttt gcagtttcca tactgggtat catcggcgga ttcctatttt
     5041 tagttgaaag tttcactgtc ctcgcccaag ccaaatcagc ctttatcttg atttttggtt
     5101 ctggtttact ggctatcggt gcttcttcgc tagttttact aggcatttcc tatgtagctc
     5161 gcttcttcgg tctactcatt gttcgcctgg tacaatttgt tcttaaaaaa agaaagagag
     5221 gtaaccagca tgcgtaaatg gacaaaagga tttctcatct ttggtgtggt gactaccgtt
     5281 atcggcttta tccttctttt tgtaggtatc caatctgacg ggattaaaag cctactttcc
     5341 atgtccaaag aacctatcta tgatagccgt acggaaaagc taacctttgg caaggaagtc
     5401 gaaaacctag aaattactct ccaccaacac gcgctcacca tcacagactc tttcgatgat
     5461 caaatccaca tttcttacca tccatctctt tctgctcacc atgatcttat caccaatcag
     5521 aacgatagaa ctctgagtct cactgataag aaactgtctg aaactccgtt tctctcttct
     5581 ggaattggtg ggattcttca tatcgcaagt agctactcta gtcgttttga agaagttatt
     5641 ctccagctac caaaagggag aactctaaaa gggatcaaca tctcagccaa tcgcggacaa
     5701 accaccatca taaatgctag ccttgaaaat gcgaccctca atacaaacag ctatatcctc
     5761 cgaattgaag gaagtcgtat caaaaacagt aaactcacaa cgcccaatat cgttaatatc
     5821 tttgatacag ttcttacaga tagtcagcta gagtcaacag agaatcactt ccacgctgaa
     5881 aatatccaag tccatggcaa ggttgaactg actgccaaag attatctcag aatcatccta
     5941 gaccagaaag aaagccaacg aattaactgg gacatctcaa gcaactatgg ttctatcttc
     6001 caattcacaa gagaaaagcc tgaatcaaga ggtacggaat taagcaaccc ttacaaaact
     6061 gaaaaaaccg atgtcaagga tcaactcatt gcgagatctg atgataatat tgatctaata
     6121 tccacaccaa gcagacgttg acaaaaacgc ttacatctgc tactatggaa gcatatttat
     6181 ctaactaaaa aggaggttct accatgaaac aagaatggtt tgaaagtaat gattttgtaa
     6241 aaacaacaag caagaacaag cctgaagagc aagctcaaga ggttgcagac aaggctgaag
     6301 aaacgatagc cgatttcgat acaccaattg aaaaaaatac tcagttagag gaggaagtct
     6361 ctcaagctga agtcgaattg gaaagccagc aagaagagaa aattgaagct cctgaagaca
     6421 gtgaagcgag aacaggaata gaagaaaaga aggcatctaa ttctactgaa gaagagccag
     6481 acctttctaa agaaacagaa aaagtcacta tagctgaaga gagccaagaa gctcttcctc
     6541 agcaaaaagc aaccacgaaa gagccacttc ttatcagtaa atctttagaa agtccttata
     6601 tccccgacca agctccaaaa tctagggata aatggaaaga gcaagtgctt gatttttggt
     6661 cttggctagt ggaagcgatc aaatctccta caagtaagtt tgaaacaagt atcacacaca
     6721 gttacacagc ctttctcttg ctcattctgt tttctgcatc ttcctttttc tttagtatct
     6781 atcacatcaa acatgcttac tatggacata tagcaagcat taacagtcgc ttccctgagc
     6841 agctagctcc tttaactctt ttttctatcg tctctatcct agtagcgaca acactcttct
     6901 tcttttcatt cctcttgggt agtttcgttg tgagacgatt tatccaccag gaaaaggact
     6961 ggacgctaga caaggttctc caacaatata gtcaactctt ggcaattcca atcttcctca
     7021 ctgctattgc tagtttcttt gctttctttg atagcctacg atttacagct ctcttgtgtg
     7081 tgattagcat tggaatcatt ctgcttgcca gtctccatat cattacaaga ccaagtcaag
     7141 caagtgaaac cgactccttc tatcaattat tcttgtctgt ccttgtgaac ggagttatta
     7201 tcctcctctt ctttgtagct gaagtggcac tgattggaga ttatcttcgt atcttggcct
     7261 ttctttaaac ttcatactct tcgaaaatca aattcaaacc acgtcagctt cgccttaccg
     7321 tactcaagta cagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtagca
     7381 atcctgtcat ccttggcagg attttttcta tgtcaaaaaa gcaagtcgat tgacctgctt
     7441 ctgctttact cttcttgtgc taatgcttta aaatctttgt ctaatatggg ttgcacttct
     7501 atttgattgg cgtctagttg gtggtaaaaa gataggggta atacctctaa gaattttgca
     7561 tagtccaagc gggcaatggc ttcatagtct tctggtttag agccatctcc tgtgatttga
     7621 accaagtcaa tctcccactg cacttcctta tccaccaatt gctcaatata ggctgcagga
     7681 acaaacggtt ctctcggtaa aactgtcttg actccttgag ctagatggta aacgccatgc
     7741 acttttcctt ctccatcctg atagaaggaa actctcgcaa agtaggcatc tgtctcttga
     7801 accgcacgca cacgcgcttc aaactgagcc aagccatctg cctctaaaaa gcttttcaag
     7861 ttctcacgac taaagaaaat aggattaaaa attccttggc aaatcgtaaa acgagctaca
     7921 gggtctgcta gataggcttg aatacttgct tggaaataag cttcaaaatc aaaaccatct
     7981 agcccttcaa tatcagtccc tgtataagca agcaaagcat ctaaaaatga cttgataatc
     8041 tgccagtctg tctttgttag taggtcagga agatcgacac ggtaagcctt ttgaccatca
     8101 gcataactga ccttaaagag aaattgtgat tgccccacta tcgcacactc gatatattcg
     8161 agacgattaa gaggctgacg gagatagact acatcatagc tatgtgactc caaaccgtct
     8221 agcaatgcca agatcgactt ggcattcaaa atctcttgtt ctcctaaaat gctctgttta
     8281 tttggaataa aaaatgtttt cgccataact ggactccttt gaaatcgttt acatacagta
     8341 taccttattt ttctgaaaga tacaaaaaca aactttatac tcttcgaaaa tctcttcaaa
     8401 ccgcgtcagc ttcgccttgc cgtagatata tgtaactgac ttcgtcagtc ttatctacaa
     8461 cctcaaagca gtgctttgag cagcctgcgg ctaacttcct agtttgctct ttgattttca
     8521 ttgagtatta gatttttgag tacaaagcat agaaaaacag cccctgagga ctgtttgatc
     8581 ttatacagta gctgcttgat ccaagctttc accgatagcg gctaggcgct caatcacttc
     8641 agcttgtgtc aattcatttt ttgaaacata gcggttacgt gggtgaacac ggcactcgtg
     8701 tgagcatcca cgaaggtact tgtcttcatt ttcttctgat gtcaagatac gacggttaca
     8761 gaagggattt ccacagttga cataacgttc acatggtgtt ccatcaaacc agtctttccc
     8821 tacgatggtt gggttgacat ggttgacatc aacggcgata cgctcgtcaa atacgtacat
     8881 ttttccatcc caaagctcac cttgaacttc tgggtcttta ccgtaagttg cgattcctcc
     8941 gtgcaattgg ccgacatctt tgtagccttc acggaccatc cagcctgaga atttctcaca
     9001 gcgaacgcca cctgtacagt aaaccacgac acgcttgtcc atgaattttt ccttgttatc
     9061 acggacccat tgtggtaact cacggaagtt gcgaatatct gggcgaatag ctccacggaa
     9121 atgtcctagg tcgtactcat aatcgttacg tgtgtcaagg acaacggtat ctttatcaag
     9181 aagcgcttct ttgaactctt ttggagacaa gtaagcacct gttgtttcaa gtgggttgat
     9241 gtcattgtca aagtcgttgt cttccaaacc aaggtggaca atttctttct tgtagcgaac
     9301 aaacatcttc ttgaaggctt gttcattttc ttcgtcaatc ttgaaccaga gttcttccat
     9361 acctgggagg ctgtgaacgt agtccatgta tttttgagtt gtttcatagt cacctgaaac
     9421 tgttccgtta attccctcgt cagcgactag gatacggcct ttaaggccga ttgatttaca
     9481 gaaagccaag tggtctgcag caaattgctc tgcattttca attggagtat aaaggtagta
     9541 aagtaagaca cgaatatctt ttgccataag atttgttctc ttttctattc ttaaattttc
     9601 taaatttttt atttatccat actagtatac ctgcttgaga aaacgaatgc aatttatttg
     9661 actggaaatt gtagaggatt ctcgaaattt cctgaatggt taaaataagg acaagagaaa
     9721 acagggatat ctatatcctt gtgccaaaaa aaccactgcc ctccccagac caacctgagg
     9781 aaagcagtga ttcttatttt aggagttagg aatgaataca cgaaatcaat ttagctgatt
     9841 attttttgtt tttcaagaat tcatcgtatt gtttttgcat ttcgttcaat actttttcgt
     9901 aggcaccttc agatttcaat ttttccatca attctggaat cgctttatct gggtctacag
     9961 taccagtgtt gatagctgta tcaaattgtt gcattgtgtt agcaatagct gagatttcag
    10021 atttcacatt gtcagtattg aagataaatc caagcgctgg agattcttta gcttctgcca
    10081 attctttctt agaattttcg atttgttggt ctgtaacgtt ttcgttgatg taaaggatcc
    10141 agttgttacc agtgttccat ccacccatgt gagtgtttcc tttgtagcca tcaagaacgc
    10201 gaacacggtt ttctttacct tcaatttttt cccagttctt gccttctgga ccgtaaacaa
    10261 gaccgttcaa gagttctggg ttggtattca agagattcaa cacttccatt gatttttctt
    10321 tgttcttaga gttgtttgag atgacaaagt tagcaacttg tgttgtttgg tttttcttga
    10381 tgaagttagt aattggtttg atttggatat ctttgttggc aacacgtgaa agcaagctgt
    10441 taccgtagtc agctggtcct actgtttctt cacgaacgaa ccaaatatct tgttgaaggt
    10501 caaatgaagt atcgcttgtt gcgacatctt ttggaatgta gccagcttca tagaatttgt
    10561 gaagagtctt caagtgttct ttgaaacgag gcacttcgta acggtttaca actttagtag
    10621 tatcgccttc aaggtcgata acgaatggaa gaccgtttgc tactgggtag tcaaagttat
    10681 cagatgggat gaaaacttta ccaatagcaa atggtactac gtctggagct ttttctttaa
    10741 tttgtttcaa gactggctca agagtttcgt aagaagtaac acctgaaata tcgataccat
    10801 atttagcaag gagagttccg ttgaaggcaa agttttgaga tgatgcaacg ttggctgcaa
    10861 ctggaacagc gtaaatctta ccatttacag tattaccctt gatgtaagct gggtcaagtg
    10921 ctttgtaaag gtctttacct tcttttttgt acaattctgt caagtcagcg taagcacctt
    10981 tttgagcatt tacaatatag ttatctgcaa aggcaatatc atagttttca ccagatgatg
    11041 tgataactga cattttctta ccatagtcac cccagccaag gtattggata tccaatttgg
    11101 caccaacttt ttcttcaatg attttgttgg catttgctaa caattcatcc aagttgtctg
    11161 gtttgtcacc gatttggtac attttgataa caggtttgtc acctgaatca gcagcttttt
    11221 tgctgttacc tgtcaaattt ccacaagcag caagacctgc agccagagcg actacactag
    11281 cagatgcaaa agcatatttt ttccagtttt tcatgataaa aactcctttt tttattttta
    11341 aacttataaa caatgtaatg atcttatact caatgaaaat caaagagcaa actagaaaac
    11401 tagccgcagg ctgctcaaag cactgctttg aggttgtaga taagactgac gaagtcagtt
    11461 acatatatct acggcaaggc gacgttgaca cggtttgaat ttgattttcg aagagtatta
    11521 acttcacaca agggaagttg ggaactgaga aatgttattt ctcaataagc actattcttt
    11581 cacaccaccg atagtcaaac cttttacaaa gtagcgttgg aaaaatggat acaaaatcgc
    11641 gattggaagg gttgcaacca caaccatggc catacgacct gtttctttcg gtagagcaac
    11701 tcccagttga ccagtcaagc cgaccgcttt ggcaatgtag tccatatttt gttggatttg
    11761 catgagcaaa tattgcaatg gatacaagtt gtcactcttg atgtaaagaa gggcgttgaa
    11821 ccagtcattc cagaaaccaa gagctgttaa gagcgtgatg gttgcgatac ctggtagtga
    11881 caatggcaaa cagatttgga agaaaatccg ggcttcactg gcaccatcga tacgagccga
    11941 ttctagaatg gcttctggaa tggtcttctt gaagaaggaa cgcatcaaga tgatgttaaa
    12001 tggtgagaga agcattggaa caatcaaggc ccaaacagta tccccaagct gaagcacacg
    12061 agtcaccatg atataacctg gtaccaaacc agcgttgaac aacatactga gcagaacgaa
    12121 gatggtaaag aatctgcgat acttaaaggt tgtccgtgaa atagcgtagg cataggttgt
    12181 tgtgataaag acatttgtca atgtcccaac tacggttaca aagacagaga tgaagagggc
    12241 ttgtaggatt ttatccttaa actgtgccaa aaactcaaaa ccgtctaagc caaattggga
    12301 tgggaagaag ctatagccgt attggaggag gcttttctcg tctgtcactg aaataatgat
    12361 aacgaataca aaaggtagga tacaagagag ggcaatcaaa cccgaaatga tactgaagaa
    12421 gatatctgct ttcttactga aggagtgaat gccgacatta tcaatttttt cttttttaat
    12481 tttctttttt gccatattct cctcctttct agaacaaagc tgagtttgga tcgactcgtc
    12541 ttgcaagcaa gtttgatagg ataaccagaa tcaaaccaac aacggattgg taaagaccgg
    12601 ctgctgcagc cataccgata tctgctgtct gagtcaaacc attaaaaaca tatacgtcca
    12661 aaacgttggt tacattgtaa agctgaccag cattgtgtgg gatttgatag aagagaccga
    12721 agtctgcgcg gaagatattt ccgactgcaa ggatggtcaa tacagttaca agcggagtca
    12781 actgaggaat ggttacgttg cgaatacgtt gccacttgct agctccgtcc actgtcgctg
    12841 cttcgtagta ggttggatca attcccatga tcgtcgcata gtacatgaca ctgctatatc
    12901 caaaaccttt ccaaatacct aggaaaagta ggagataggg ccagatgccc aggtcagcgt
    12961 agaaattgac ttctttgaga ccaagacttt ccaatagatg attgaacacc cctttatcaa
    13021 tatttaggaa ggcatctgta aagaaactga tgataaccca agacaagaag taagggaaca
    13081 acatagaagt ttggaaaatc ttcaccattc tcttagaacg gagctcgctg aggataatgg
    13141 caatccctac agatacaact aaacctagaa agataaagcc aagattgtag aggacagtat
    13201 ttcgtgtgat aataaaggcg tctcttgaac taaataagaa tctgaaatta tcgagtccga
    13261 cccatttact atttatgata ctatctatga aaccattact ggtcatgtgg tagtctttga
    13321 aggcaaccac gttcccaaat actggaatgt aaaagaatag aatcaaccag agtgcccctg
    13381 gcaaaaccat caagagaaag atccagttgt ctctcaaggt ttttgaaaac ttattcataa
    13441 tttcctccct ttttattttg atatccatct aaaaattctt ttttagactt ttgataacga
    13501 ttacattatt agtatactcc tatttgcagg ttaggttaaa ctcctaatta tagaaaaaac
    13561 tccacaaatt atgtagcaga tttaaaactt tatcaccact atcaaacaaa tgtcctaaat
    13621 caattgttta ttttatctct attagcccag tgatggcgtc actctgttat aagcatccaa
    13681 caacggggta tactgaaaaa tctccagact agggaactca gcgatagttc ctaatctgga
    13741 gatttttaat atgttattag gcgtttgctt tcaacttagc aataacctct ttaagattat
    13801 caatcaactc tgcttcagta tgctcagagc ctttttcatc tgccaagaac aaaactgctt
    13861 tttgaagttc ttcttgagag ttttcaagga catccttatc tgctgtttca aggtttgagt
    13921 ctgcttacta atactagact aaaatcaaaa agcattatat aacagtgata tgaaatcaac
    13981 taaagaagaa atccaaacta tcaaaacact tttaaaagac tctcgtacag ctaaatatca
    14041 taaacgcctt caaatcgttc tatagtaaaa tgaaacaaga acaggacaaa tcgatttcta
    14101 acaatgtttt agaagtagag gtgtactatt ctagtttcaa tccattatat ttcgtctgat
    14161 gggcaaatct tataaagaga ttatagaac
//
LOCUS       DAVLGK010000053        13347 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLGK010000053 DAVLGK010000000
VERSION     DAVLGK010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.054"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            36..257
                     /locus_tag="VXE01_001856"
     CDS             36..257
                     /locus_tag="VXE01_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV0750714.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            311..982
                     /locus_tag="VXE01_001857"
     CDS             311..982
                     /locus_tag="VXE01_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0750715.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(1034..1231)
                     /locus_tag="VXE01_001858"
     CDS             complement(1034..1231)
                     /locus_tag="VXE01_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0750716.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            1224..2132
                     /locus_tag="VXE01_001859"
     CDS             1224..2132
                     /locus_tag="VXE01_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0750717.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            2129..2590
                     /locus_tag="VXE01_001860"
     CDS             2129..2590
                     /locus_tag="VXE01_001860"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV0750718.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            2580..3467
                     /locus_tag="VXE01_001861"
     CDS             2580..3467
                     /locus_tag="VXE01_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0750719.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEYVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKIL
                     EFKADIPEIFKETLERLRK"
     gene            3470..5353
                     /gene="cbpE"
                     /locus_tag="VXE01_001862"
                     /gene_synonym="pce"
     CDS             3470..5353
                     /gene="cbpE"
                     /locus_tag="VXE01_001862"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV0750720.1"
                     /translation="MKKKLTSLALVGAFLDLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            5433..6563
                     /locus_tag="VXE01_001863"
     CDS             5433..6563
                     /locus_tag="VXE01_001863"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV0750721.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEVEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            6573..7835
                     /locus_tag="VXE01_001864"
     CDS             6573..7835
                     /locus_tag="VXE01_001864"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV0750722.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            7839..8636
                     /gene="proC"
                     /locus_tag="VXE01_001865"
     CDS             7839..8636
                     /gene="proC"
                     /locus_tag="VXE01_001865"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV0750723.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     SSLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            8856..9494
                     /locus_tag="VXE01_001866"
     CDS             8856..9494
                     /locus_tag="VXE01_001866"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV0750724.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            9491..10381
                     /locus_tag="VXE01_001867"
     CDS             9491..10381
                     /locus_tag="VXE01_001867"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV0750725.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFESLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            10421..10738
                     /gene="yabA"
                     /locus_tag="VXE01_001868"
     CDS             10421..10738
                     /gene="yabA"
                     /locus_tag="VXE01_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV0750726.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            10741..11610
                     /gene="rsmI"
                     /locus_tag="VXE01_001869"
     CDS             10741..11610
                     /gene="rsmI"
                     /locus_tag="VXE01_001869"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV0750727.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            11837..12355
                     /locus_tag="VXE01_001870"
     CDS             11837..12355
                     /locus_tag="VXE01_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV0750728.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            12464..13108
                     /locus_tag="VXE01_001871"
     CDS             12464..13108
                     /locus_tag="VXE01_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV0750729.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVRL
                     GLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYIE
                     NNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(13097..>13347)
                     /locus_tag="VXE01_001872"
     CDS             complement(13097..>13347)
                     /locus_tag="VXE01_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0750730.1"
                     /translation="YQGLMKIYPQAQTPRKSSKLKPLTVEDKACNHALSKERSKVENI
                     FAKVKTFKMISTTYRNHRKRFGLRMNLIAGIINHELGF"
BASE COUNT         4073 a         2254 c         3122 g         3898 t
ORIGIN      
        1 tcaactaatc tgaagaataa tggaggaaat atatcatgat tttaatgaca aaaaatataa
       61 atctaacaaa tgaagaatta gagctgatac aaggtggagc agattcatat ggtaaaaatc
      121 ctaatggtag gtacgattgg gaaatagaac cagtattaac tctgccggtt catggatttt
      181 gtcccagagg cacctatgat ttaggatata ttggaggagg caatcatctt tgcaaaggaa
      241 gtgctgcgag attttaagta aaatttatta gtaatatgaa gaaacaaggg gagaaagcag
      301 agaatttaat atgaaaaaac gggctattca aattttacta gcattgtcct taatttttta
      361 caaatcaact tggttttgga gagttttcaa tcacctcgca aagccctatc taccagcaag
      421 tcgtgaattt tttcagattc tgcttttgat ggagagcgga gttcttttct tagcggtcat
      481 ctatctactg gtttttgcag gaaagaaaat ttttcatttc aagtggcagc tgaggtactt
      541 catctacctt ttactgggct acatcatttc atatatgtct gacttcctct tttcgtattt
      601 catatccctg tcttcaaatc agatttcttt gaatgaaacg atagaaatga tggggagaca
      661 ggagttccct tatttcttgc tcatcgtttg cttcatcgcc cctattgctg aggaattgat
      721 ttatcgaggt gtgcttatga caaccttttt caaaaactca ccttggtacg gagatgtttt
      781 gctttctgct attattttcg gttatattca tatcaatttt gctttaactc ctcttgcttt
      841 tttcatttat gctagtggag gtctgatttt agctctattg tatcgcatga ctaaaaatct
      901 ctactatcca atactagttc atattctcat caatatcact gccttctggg atgtttggtt
      961 actcctattt tcaggaagtt agcttactaa aaaaatgtcg gaattttccg gcattttctt
     1021 ttttcacaaa tagtcaacgt ttttctttcc gatactgaag tggtgtgtag ccacttattt
     1081 ttttgaattg attttgaaaa taagattggc gtgagaaagg cagatagtga agatagttaa
     1141 gaagaatagg atgttctttt ttcctttttg gaaaacttct aaaatatggt ataatgaaaa
     1201 gataaagaag ttgggggtag aagatgaaca ttcaacaatt acgctatgtt gtggctattg
     1261 ccaatagtgg tacttttcgt gaagctgctg aaaagatgta tgttagtcag ccgagtctgt
     1321 ctatttctgt tcgtgatttg gaaaaagagt tgggctttaa gattttccgt cggaccagct
     1381 cagggacttt cttgacccgt cgtgggatgg aattttatga aaaagcgcaa gaattggtta
     1441 aaggatttga tatttttcaa aatcagtatg ccaatcctga agaagaaaaa gatgaatttt
     1501 ccgttgctag ccagcactat gacttcttac caccaactat tacggccttt tcagagcgct
     1561 atcctgacta taagaacttc cgtatttttg aatcaactac tgttcaaata ttagatgaag
     1621 tggcgcaagg gcatagtgag attgggatta tctacctcaa caatcaaaat aaaaagggga
     1681 ttatgcaacg ggttgaaaag ttaggtctgg aggtcatcga attgattcct ttccataccc
     1741 atatttatct ctgtgagggt catcctttag cccagaaaga ggaattagtc atggaggatt
     1801 tagcggattt accaacggtt cgtttcactc aagagaaaga cgagtacctt tattattcag
     1861 agaactttgt cgataccagc gctagctcac agatgtttaa tgtgacagac cgtgccacct
     1921 tgaatggtat tttggagcgg acggacgcct atgcgacagg ttctggattt ttagatagtg
     1981 acagtgttaa tggcattaca gttattcgtc tcaaggataa cctagataac cgcatggtct
     2041 atgttaaacg tgaagaagtg gagcttagtc aagctgggac tctcttcgta gaagtcatgc
     2101 aagaatattt tgatcaaaag aggaaatcat gaaaaaaaga gcaatagtgg cagtcattgt
     2161 actgctttta attgggctgg atcagttggt caaatcctat atcgtccagc agattccact
     2221 gggtgaagtg cgctcctgga ttcccaattt cgttagcttg acctacctgc aaaatcgagg
     2281 tgcagccttt tctatcttac aagatcagca gctgttattc gctgtcatta ctctggttgt
     2341 cgtgataggt gccatttggt atttacataa acacatggag gactcattct ggatggtctt
     2401 gggtttgact ctaataatcg cgggtggtct tggaaacttt attgacaggg tcagtcaggg
     2461 ctttgttgtg gatatgttcc accttgactt tatcaacttt gcaattttca atgtggcaga
     2521 tagctatctg acggttggag tgattatttt attgattgca atgctaaaag aggaaataaa
     2581 tggaaattaa aattgaaact ggtggtctgc gtttggataa ggctttgtca gatttgtcag
     2641 aattatcacg tagtctcgcg aatgaacaaa ttaaatcagg ccaggtcttg gtcaatggtc
     2701 aagtcaagaa agctaaatac acagtccaag agggtgatgt cgtcacttac catgtgccag
     2761 aaccagaggt attagagtat gtggctgagg atcttccgct agaaatagtc taccaagatg
     2821 agtatgtggc tgtcgttaac aaacctcagg gaatggttgt gcacccgagt gctggtcata
     2881 ccagtggaac cctagtaaat gccctcatgt atcatattaa ggacttgtcg ggtatcaatg
     2941 gggttctgcg tccagggatt gttcaccgta ttgataagga tacgtcaggt cttctcatga
     3001 ttgctaaaaa cgatgatgcg catctagtac ttgcccaaga actcaaagat aaaaagtctc
     3061 tccgcaaata ttgggcgatt gttcatggaa atctgcctaa tgatcgtggt gtaattgaag
     3121 cgccgattgg ccggagtgaa aaagaccgta agaaacaggc tgtaactgct aaagggaagc
     3181 ctgcagtgac gcgttttcac gtcttggaac gctttggcga ttatagctta gtagagttgc
     3241 aactggagac agggcgcact catcaaatcc gtgtccacat ggcttatatc ggccatccag
     3301 tcgctggtga tgaggtctat ggtcctcgca agactttgaa aggacatgga caatttcttc
     3361 atgccaagac tttaggtttt actcatccga gaacaggtaa gatcttggaa tttaaagcag
     3421 atatcccaga gatttttaag gaaaccttgg agagattgag aaagtaagaa tgaaaaagaa
     3481 attaactagt ttagcacttg taggcgcttt tttagatttg tcatggtatg ggaatgttca
     3541 ggctcaagaa agttcaggaa ataaaatcca ctttatcaat gttcaagaag gtggcagtga
     3601 tgcgattatt cttgaaagca atggacattt tgccatggtg gatacaggag aagattatga
     3661 tttcccagat ggaagtgatt ctcgttatcc atggagagaa ggaattgaaa cgtcttataa
     3721 gcatgttcta acagaccgtg tctttcgtcg tttgaaggaa ttgggtgtcc aaaaacttga
     3781 ttttattttg gtgacccata cccacagtga tcatattgga aatgttgatg aattactgtc
     3841 tacctatcca gttgaccgag tctatcttaa gaaatatagt gatagtcgta ttactaattc
     3901 tgaacgtcta tgggataatc tgtatggcta tgataaggtt ttacagactg ctgcagaaaa
     3961 aggtgtttca gttattcaaa atatcacaca aggggatgct cattttcagt ttggggacat
     4021 ggatattcag ctctataatt atgaaaatga aactgattca tcgggtgaat taaagaaaat
     4081 ttgggatgac aattccaatt ccttgattag cgtggtgaaa gtcaatggca agaaaattta
     4141 ccttgggggc gatttagata atgttcatgg agcagaagac aagtatggtc ctctcattgg
     4201 aaaagttgat ttgatgaagt ttaatcatca ccatgatacc aacaaatcaa ataccaagga
     4261 tttcattaaa aatttgagtc cgagtttgat tgttcaaact tcggatagtc taccttggaa
     4321 aaatggtgtt gatagtgagt atgttaattg gctcaaagaa cgaggaattg agagaatcaa
     4381 cgcagccagc aaagactatg atgcaacagt ttttgatatt cgaaaagacg gttttgtcaa
     4441 tatttcaaca tcctacaagc cgattccaag ttttcaagct ggttggcata agagtgcata
     4501 tgggaactgg tggtatcaag cgcctgattc tacaggagag tatgctgtcg gttggaatga
     4561 aatcgaaggt gaatggtatt actttaacca aacgggtatc ttgttacaga atcaatggaa
     4621 aaaatggaac aatcattggt tctatttgac agactctggt gcttctgcta aaaattggaa
     4681 gaaaattgat ggaatctggt attattttaa caaagaaaat cagatggaaa ttggttgggt
     4741 tcaagataaa gagcagtggt attatttgga tgttgatggc tctatgaaga caggttggct
     4801 tcaatataag gggcaatggt attactttgc tccatcaggg gaaatgaaaa cgggctgggt
     4861 aaaagataaa gaagcctggt actatatgga ttctactggt atcatgaaga caggtgagat
     4921 agaagttgct ggacatcatt actatctaga agaatcagga gctatgaagc aaggctggct
     4981 taaaaaggca aatgattggt atttctacaa gacagatggt tcacgagcta taggttggat
     5041 taaagataag gataaatggt acttcttgaa agaaaatggt caattacttg tgaatggtaa
     5101 gacaccagaa ggctatactg tggattcaag tggtgcctgg ttagtggatg ttccgatcga
     5161 gaaatctgct acaattaaaa ctacaagtca ttcagaaata aaagaatcca aagaagtagt
     5221 gaaaaaggat cttgaaaata aagaaacgag tcaacatgaa agtgttacaa attcttcaac
     5281 tagtcaagat ttgacatcct caacttcaca aagctctgaa acgagtgtaa acaaatcgga
     5341 atcagaacag tagtagaaaa gaaggtttta gggccttctt tttcctatca actcttttct
     5401 atttcctgtt attcatgtta taatggataa atatgaataa tcggagtgag actatgaaat
     5461 acaaacggat tgtctttaag gtgggtactt cttctctgac aaatgaggat ggaagtttat
     5521 cacgtagtaa ggtaaaggat attacccagc agttggctat gctgcacgag gctggtcatg
     5581 agttgatttt ggtgtcttca ggtgccattg cggctggttt tggagcctta ggatttaaaa
     5641 agcgtccgac taaaattgct gataaacagg cttcagcagc ggtagggcag ggacttttgt
     5701 tggaagaata tacgaccaat cttctcttgc gtcaaatcgt ttctgcacaa atcttgctga
     5761 cccaagatga ctttgtggat aagcgtcgtt ataaaaatgc ccatcaggct ttgtcggttt
     5821 tgctcaaccg tggggcaatt cctatcataa atgagaatga tagtgtcgtt attgatgagc
     5881 tcaaggttgg ggacaatgac actctaagtg ctcaagtagc ggcgatggtc caagcagacc
     5941 ttttagtttt cttgacagat gtggacggtc tctatactgg aaatcctaat tcagatccaa
     6001 gagccaaacg cttggagaga atcgagacca tcaatcgtga gattattgat atggctggtg
     6061 gagctggttc gtcaaacgga actgggggta tgttaaccaa aatcaaggct gcaactatcg
     6121 cgacggaatc aggagttcct gtttatatct gctcatcctt gaaatcagat tccatgattg
     6181 aggcggcaga ggagaccgag gatggttctt actttgttgc tcaagagaag gggcttcgta
     6241 cccagaaaca atggcttgcc ttctatgctc agagtcaagg ttctatttgg gttgataaag
     6301 gggctgcgga agctctctct caacatggaa agagtcttct cttatctggt atcgttgaag
     6361 tagaaggagc cttttcttac ggtgatatcg tgacagtatt tgacaaggaa agtggaaaat
     6421 cacttggaaa aggacgcgtg caatttggag catctgcttt ggaggatatg ttgcgttctc
     6481 aaaaagccaa gggtgtcttg atttaccgtg acgactggat ttccattact cctgaaatcc
     6541 aactactttt tacagaattt tagaggtaaa ctatggtgag tagacaagaa caatttgaac
     6601 aggtacaggc tgttaaaaaa tcgattaaca cagctagtga agaagtgaaa aaccaagcct
     6661 tgctagccat ggctgatcac ttagtggctg ctactgagga aattttagcg gctaatgccc
     6721 tcgatatggc agcggctaag gggaaaatct cagatgtgat gttggatcgt ctttatttgg
     6781 atgcagatcg tatagaagcg atggcaagag gaattcgtga agtggttgcc ttaccagatc
     6841 caatcggtga agttttagaa acaagtcagc ttgaaaatgg tttggttatc acaaaaaaac
     6901 gtgtagctat gggtgtcatc ggtattatct atgaaagccg tccaaatgtg acgtctgatg
     6961 cggctgcttt gactcttaag agtggaaatg cggttgttct tcgtagtggt aaggatgcct
     7021 atcaaacaac ccatgccatt gtcacagcct tgaagaaggg cttggagacg actactattc
     7081 atccaaatgt gattcaactg gtggaggata ctagccgtga aagtagttat gctatgatga
     7141 aggccaaggg ctatctagac ctcctcattc ctcgtggagg agctggcttg atcaatgcag
     7201 tggttgagaa tgcgattgta cctgttatcg agacagggac tgggattgtc catgtctatg
     7261 tggataagga tgcagacgaa gacaaggcgc tgtctatcat caacaatgct aaaaccagtc
     7321 gtccttctgt ttgtaatgcc atggaggttc tgctggttca tgaaaacaag gcagcaagca
     7381 tccttcctcg cttggatcaa atgctggttg cagagcgtaa ggaagctgga ctggaaccaa
     7441 ttcaattccg cttggatagc aaagcaagcc agtttgtttc aggtcaagca gctgagaccc
     7501 aagactttga caccgagttt ttagactatg tccttgctgt taaggttgtg agcagtttag
     7561 aagaagcggt tgcgcacatt gaatcccaca gcacccatca ttcggatgct attgtgacgg
     7621 aaaatgctga agctgcagca tactttacag atcaagtgga ctctgcagcg gtgtatgtta
     7681 atgcctcaac tcgtttcaca gatggaggac aatttggtct tggttgtgaa atggggattt
     7741 ctactcagaa attgcacgcg cgtggtccaa tgggcttgaa agagttgacc agctacaagt
     7801 atgtggttgc tggtgatggg cagataaggg agtaagagat gaagattgga tttatcggtt
     7861 tggggaatat gggtgctagc ttggcaaaat ctgtcttgca gactaggacg tcagatgaga
     7921 ttctccttgc caatcgtagt caagctaagg tagatgcttt cattgcagac tttggtggtc
     7981 aggcttccag caatgaagaa atgtttgcag aagcagatgt gatttttcta ggagttaagc
     8041 ctgctcagtt ttctgaactg ctttctcaat accagaccat ccttgaaaaa agagaaagtc
     8101 ttcttttgat ttcgatggca gctggattga ccttagaaaa actatcaagt cttatcccaa
     8161 gccaacaccg aattattcgt atgatgccta atacccctgc ttctatcggg caaggagtga
     8221 ttagttatgc cttgtctcct aattgcaggg ctgaggacag tgagatcttt tgtcagcttt
     8281 tagccaaggc tggtctcttg gttgaattag gagaaagctt aatcaatgca gcgacaggtc
     8341 ttgcaggttg tggaccagcc tttgtctatc tctttattga ggccttggca gatgcaggtg
     8401 ttcagacggg attaccacga gaaacagcct tgaaaatggc agcccaaact gtggtaggag
     8461 ctgggcaatt ggtcctagaa agccagcaac atcctggagt tttgaaagat caagtttgta
     8521 gtccaggcgg ttcgactatt gctggcgtag caagcctaga agcgcatgct tttcgaggca
     8581 cagtcatgga ggcagttcat caagcctata aacgaacaca agaactaggt aaataagagg
     8641 tagctttgac tgcctctttt atggtggttg atactcttcg aaaatcaaat tcaaactgcg
     8701 tcagcttcac cttgccgtac tcaagtacag cctgcggcta gcttcctagt ttgctctttg
     8761 attttcattg agtatgaaat gagaagacaa aaagattgtc acaaacccct atttttttga
     8821 tagaatagaa gtagtaaaaa agaaatgagt tagacatgtc aaaaggattt ttagtctctc
     8881 ttgagggacc agagggagca ggcaagacca gtgttttaga ggctctgcta ccaattttag
     8941 aggaaaaagg agtagaggtg ttgacgaccc gtgaacctgg cggagtcttg attggggaga
     9001 agattcggga agtgattttg gatccaagtc atactcagat ggatgctaaa acagagctac
     9061 ttctctatat tgccagtcgc agacagcatt tggtggaaaa agttcttcca gcccttgaag
     9121 ctggcaagtt ggtcatcatg gatcgtttta tcgatagttc tgttgcctat cagggatttg
     9181 gtcgtggctt agatattgaa gccattgact ggctcaatca gtttgcgaca gatggcctca
     9241 aacccgattt gacactctat tttgacatcg aggtggaaga agggctggct cgtattgctg
     9301 ctaatagtga ccgcgaggtt aatcgtttgg atttggaagg gttggacttg cataaaaaag
     9361 ttcgtcaagg ctacctttct cttctggata aagagggaaa tcgcattgtc aagattgatg
     9421 ctagtctccc tttggagcaa gttgtggaaa ctaccaaggc tgtcttattt gacggaatgg
     9481 gcttggccaa atgaaacaag atcaactaaa ggcttggcaa ccagctcagt ttgaccgttt
     9541 tgtccgtatc ttagaacaag accagctcaa tcacgcctat ctcttttcag gtttctttga
     9601 aagcttggaa atggcgcaat ttttagctaa gagcctcttt tgtacggata aagttggcgt
     9661 cttaccatgt gagaaatgcc gaagttgcaa gctgattgaa cagggagagt ttccagatgt
     9721 caccttgatt aagccagtca atcaggtcat caagacagaa cgcattcggg aattggtggg
     9781 acagttttct caagcaggga ttgaaagcca gcaacaggtc tttatcatcg agcaagcgga
     9841 taaaatgcat cccaacgcag ccaattctct gctcaaggtc atcgaagaac cccagagtga
     9901 agtttatatt ttcttcttga ctagcgatga ggaaaagatg ttaccgacaa tccgaagtcg
     9961 gactcagatc ttccacttta aaaagcaaga agaaaaactt atcttactct tagaacaaat
    10021 gggacttgtt aagaaaaaag cgactctttt agctaagttt agtcaatcgc gagctgaagc
    10081 agaaaagttg gctaatcagg caagtttttg gaccttggtc gatgaaagtg aacgcctgct
    10141 gacttggtta gtagctaaga aaaaagaaag ttatctacag gttgccaaat tagccaactt
    10201 ggcagatgat aaggaaaaac aggatcaggt tttacggatt cttgaagttc tctgtgggca
    10261 ggacctcttg caggtaagag taagagtgat tctacaagat ttactagaag ctagaaaaat
    10321 gtggcaagct aatgtcagct ttcaaaatgc catggaatat ctggtcttga aagaaatata
    10381 aactcaaaaa tgaatgataa agaaaggaaa gggctgtttt atggacaaaa aagaattatt
    10441 tgacgcgctg gatgattttt cccaacagtt attggtaacc ttggccgatg tggaagccat
    10501 caagaaaaat ctcaagagcc tggtagagga aaatacagct cttcgtttgg aaaattctaa
    10561 gttgcgagaa cgcttgggtg aggtggaagc agatgctcct gtcaaggcca agcatgttcg
    10621 tgaaagtgtc cgtcgcattt accgtgatgg atttcacgta tgtaatgatt tttatggaca
    10681 acgtcgagag caggacgaag aatgtatgtt ctgtgatgag ttgttataca gggagtaggc
    10741 atgcaaattc aaaaaagttt taaggggcag tctccctatg gcaagctgta tctagtggca
    10801 acgccgattg gcaatctaga tgatatgact tttcgtgcta tccagacctt gaaagaagtg
    10861 gactggattg ctgctgagga tacgcgcaat acaggtcttt tgctcaagca ttttgacatt
    10921 tccaccaagc agatcagttt tcatgagcac aatgccaagg aaaaaattcc tgatttgatt
    10981 ggtttcttga aagcagggca aagtattgct caggtctctg atgccggttt gcctagcatt
    11041 tcagaccctg gtcatgattt agttaaggca gctattgagg aagaaattgc agttgtgaca
    11101 gttccaggtg cctctgcagg aatttctgcc ttgattgcca gtggtttagc gccacagcca
    11161 catatctttt acggtttttt accgagaaaa tcaggtcagc agaagcaatt ttttggcttg
    11221 aaaaaagatt atcctgaaac acagattttt tatgaatcac ctcatcgtgt agcagacacg
    11281 ttggaaaata tgttagaagt ctacggtgac cgctccgttg tcttggtcag ggaattgacc
    11341 aaaatctatg aagaatacca acgaggtact atctctgagt tattagaaag cattgctgaa
    11401 acgccactca agggcgaatg tcttctcatt gttgagggtg ccagtcaggg tgtggaggaa
    11461 aaggacgagg aagacttgtt cgtagaaatt caaacccgca tccagcaagg tgtgaagaaa
    11521 aaccaagcta tcaaggaagt cgctaagatt taccagtgga ataaaagtca gctctacgct
    11581 gcctaccacg actgggaaga aaaacaataa agggagacag gatgtaataa ttctgtctgt
    11641 ttctgtttaa cttaattagt gatggtaata taaagatgta tcacttggta tagaagcttt
    11701 ggtattaagt tttttattaa gcccatacgg aataccgatg gttggagcag cagttatagc
    11761 gttcttagaa ggtataaata gaaaaataag gtcattttaa atcaaaggat tgataaatca
    11821 gaaagaaggt gattttttgc gaacatacga aaataaagaa gaactaaaag ctgagataga
    11881 gaaaacattt gagaaatata ttttagaatt tgataatatt ccagaaaatt taaaagataa
    11941 gagagctgat gaagttgaca gaactccagc agaaaacctt gcttatcagg ttggttggac
    12001 caacttggtt cttaaatggg aagaagatga aagaaagggg cttcaagtaa aaacaccatc
    12061 ggataaattt aaatggaatc aacttggtga attatatcag tggttcacag atacctacgc
    12121 tcatttatct ctgcaagagt tgaaagcaaa attaaatgaa aatattaatt ctatctctgc
    12181 aatgattgat tcgttgagtg aggaagaatt atttgaaccg catatgagaa agtgggctga
    12241 tgaagcgact aaaacagcga cttgggaagt gtataagttt attcatgtaa atacggttgc
    12301 accttttgga actttcagaa ctaaaatcag aaaatggaag aagatagtat tataaattat
    12361 atttttaact ttaaaaaatt tcataaaaat ggttaccaaa ggcgatagaa gaaaaactat
    12421 cgtctttttc tttgcaaatt tttaagaagg gaggtgatct tgcatggact ttgaatattt
    12481 ttataacaga gaagcggaaa gatttaactt cttaaaagta ccggagatat tagttgatag
    12541 agaagaattt cggggcttat cagcagaagc aattatcctt tattccatac ttcttaaaca
    12601 gacaggaatg tcatttaaga ataactggat agacaaggaa ggcagagtat ttatctttac
    12661 tgtcgaagaa attatgaaaa gaagaaatat ctcaaagcca actgccataa aaacattaga
    12721 tgagcttgat gtaaaaaaag gaataggact gatcgaaaga gtaaggcttg gacttggtaa
    12781 gccgaacatc atttatgtta aagactttat gagtatattt caggtaaaag aaaatgactt
    12841 acagaagtca aaaaacttaa cttcagaagt aaaagatttt aacctcagaa gtaaagaaaa
    12901 tgaacttcaa gaggttaaga accttgactc taactatata gagaataata agagtaagta
    12961 tagtaagaga gaatatagtt ttggtgaaaa cggacttgga acatttcaaa atgtgttttt
    13021 agctgctgaa gatatatcgg atttacaaat cataatgaac tcacagcttg agaattacat
    13081 tagacttcct gcaaaactag aatcctagtt catgattgat aataccagca atcaaattca
    13141 ttcgtaatcc gaagcgttta cgatgatttc gataggttgt tgaaatcatt ttaaacgttt
    13201 ttactttggc aaagatgttc tcaaccttgc ttctctcctt ggatagcgca tggttacagg
    13261 ctttatcttc aactgttagt ggcttgagtt tgctggattt acgtggagtt tgtgcttgag
    13321 gatatatctt catgagccct tgataat
//
LOCUS       DAVLGK010000054        11999 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLGK010000054 DAVLGK010000000
VERSION     DAVLGK010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.055"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..2105)
                     /locus_tag="VXE01_001873"
     CDS             complement(<1..2105)
                     /locus_tag="VXE01_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEV0750731.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEEVRRGN
                     NLTVTSSGDEVESHYQSILEKVRKSLEKDRHTQNVDLIKKLQDIKRTYLYNLKEKPEA
                     ELTSKTKKELDAAFEKFKKEPELTKKLAEAEKKVAEAEKKAKDQKEEDHRNYPTNTYK
                     TIELEIAEAEVGVAKAELELAQAQVQIPQDTEKINAAKAKVEAAKSNVKKLEKIKSDI
                     EKTYLYKLDNSTKKTPKPRVRRNSPEIKAKGRVKNYKEANIELSKYMTDLYKLDNSTK
                     ETPKSRVRRNSPQVGDSRELKETIDKAKETLSTYMVTRLTKLDPSVFWFADLLMDAKK
                     VVEEYKTKLEDASDKKSVEDLRKEAEGKIESLIVTHQNREKENQPAPQPGGQAGGSMV
                     VPPVTQTPPSTSQSPGQKATEAEKKKLQDLIRQFQEALNKLDDETKTVPDGAKLTGEA
                     GKAYNETRTYAKEVVDKSKKLLSQTAVTMDELAMQLTKLNDAMSKLKEAKAKLVPEVK
                     PQPENPEPKPQPEGEKPSVPDINQEKEKAKLAIATYMSKILDDIKKHHLKKEKHHQIV
                     ALIKDLDKLKKQALSEIDNVNTKVEIENTVHKVFADMDTVVTKFQKGLIQNTPQVPEA
                     PKSPEVPKVSDTPKAPDTPQVPEAPAPETPAPAPEAPKTGWKQENGMWYFYNTDGSMA
                     TGWLEYNGSWYYLNANGAMA"
     gene            complement(2184..2711)
                     /locus_tag="VXE01_001874"
     CDS             complement(2184..2711)
                     /locus_tag="VXE01_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV0750732.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(2806..4146)
                     /gene="hk06"
                     /locus_tag="VXE01_001875"
     CDS             complement(2806..4146)
                     /gene="hk06"
                     /locus_tag="VXE01_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV0750733.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKQLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVNVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVSNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(4143..4796)
                     /gene="rr06"
                     /locus_tag="VXE01_001876"
     CDS             complement(4143..4796)
                     /gene="rr06"
                     /locus_tag="VXE01_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV0750734.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(5117..7549)
                     /locus_tag="VXE01_001877"
     CDS             complement(5117..7549)
                     /locus_tag="VXE01_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0750735.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQAHSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDEESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(7551..8009)
                     /locus_tag="VXE01_001878"
     CDS             complement(7551..8009)
                     /locus_tag="VXE01_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV0750736.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            complement(8128..8856)
                     /locus_tag="VXE01_001879"
     CDS             complement(8128..8856)
                     /locus_tag="VXE01_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750737.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(8856..9863)
                     /locus_tag="VXE01_001880"
     CDS             complement(8856..9863)
                     /locus_tag="VXE01_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0750738.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(9901..10659)
                     /locus_tag="VXE01_001881"
     CDS             complement(9901..10659)
                     /locus_tag="VXE01_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0750739.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            complement(10622..10912)
                     /locus_tag="VXE01_001882"
     CDS             complement(10622..10912)
                     /locus_tag="VXE01_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV0750740.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(10983..11085)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(11168..>11999)
                     /gene="cbpD"
                     /locus_tag="VXE01_001883"
     CDS             complement(11168..>11999)
                     /gene="cbpD"
                     /locus_tag="VXE01_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0750741.1"
                     /translation="KDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLASGTVIDYYY
                     PGEKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTK
                     SAIKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQ
                     NYQNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEM
                     QTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV
                     "
BASE COUNT         3337 a         2746 c         2044 g         3872 t
ORIGIN      
        1 gccatagcac cattagcgtt gagatagtac catgagccat tgtattctag ccagcctgtt
       61 gccattgaac catcagtatt gtagaagtac cacataccgt tttcttgttt ccagcctgtt
      121 tttggagctt ctggagctgg agccggagtt tctggagctg gtgcttctgg aacctgcggt
      181 gtgtccggag cctttggtgt atctgaaacc tttggtacct ctgggctctt tggtgcttct
      241 ggaacctgcg gtgtgttctg aattaagcct ttttggaatt tagtaacaac cgtatccatg
      301 tctgcaaata ccttgtggac tgtattctca atttctactt tggtatttac attatcaatt
      361 tcagaaagtg cttgcttttt aagtttatca aggtccttaa taagagcaac aatctgatga
      421 tgtttttctt tcttcagatg atgtttcttt atatcatcta aaatcttgct catgtatgtt
      481 gctatagcaa gtttagcttt ttctttctcc tgattaatat ctggtacgct tggtttctca
      541 ccctctggtt gtggttttgg ctctgggttt tccggctgtg gtttaacctc tggtaccaat
      601 ttcgctttag cttctttcaa tttagacatg gcatcgttca atttggttaa ttgcattgcc
      661 aattcatcca ttgtcactgc tgtctgtgat agaagcttct tgcttttgtc aacaacttct
      721 ttcgcataag ttctagtctc attataggct tttccagctt ctcctgtgag tttagcccca
      781 tctggaacag tctttgtttc atcgtctagt ttgttcaagg cttcttggaa ttgacgaatc
      841 aagtcttgta actttttctt ttcagcttcg gtcgcctttt gtcctggact ttgggaagtt
      901 gatggaggtg tttgcgtcac cggtggtaca accattgaac cacctgcttg tcctcctggt
      961 tggggtgctg gttggttttc tttttctcta ttttggtgag tcacgataag agactctatt
     1021 tttccttctg cttcctttcg caagtcttct accgattttt tatctgaagc atcctctaat
     1081 tttgtcttgt attcttccac aaccttctta gcatccataa gaagatctgc aaaccaaaaa
     1141 acagatggat ccagcttcgt taaacgagtt accatatagg tagacagagt ttctttcgct
     1201 ttgtctatcg tttccttaag ttctctcgaa tcgcctactt gcggagaatt tcttcgcact
     1261 ctagattttg gcgtttcttt ggttgagtta tctaatttat acaaatcagt catatattta
     1321 gaaagttcaa tattagcctc tttataattt ttgactctac ccttagcttt tatttccgga
     1381 gaatttcttc gcactctagg ttttggcgtt tttttggttg agttatctaa tttatacaaa
     1441 tacgtttttt caatatctga tttaattttt tctagttttt taacattact tttagcagct
     1501 tctactttag ctttagcagc attaattttc tcagtatctt gaggtatttg gacttgagct
     1561 tgtgcaagct caagctctgc cttggcgacc cctacttctg cttccgcaat ttccagttcg
     1621 attgttttgt aagtattggt tgggtagtta cggtgatctt cttctttttg atccttggct
     1681 tttttctcag cttctgcaac cttcttctca gcttctgcta attttttagt aagttctggt
     1741 tcttttttaa acttctcaaa agctgcgtct aactcttttt ttgtttttga cgtcaactca
     1801 gcttccggct tctcttttaa attatacaaa tacgttctct taatgtcttg caactttttg
     1861 attaagtcga cattttgggt atgtcgatct ttttccaaac tttttctgac cttctccaat
     1921 atactttgat aatgcgactc gacttcatcc ccactagatg taaccgtgag gttattccct
     1981 cttctaacct cttctgcatg aactactcct cctaagaaca aactagcaac tactacacta
     2041 gctactccaa tactaaattt acgaattgaa taatgtactt ttctttcgct ttttgatgca
     2101 aacatgttta tttccttcta tattttttct ttaaccttac tatatcactt caatatgaac
     2161 tgtatataaa tcgaattttg tatttatctc tttatgcttc catttgggat tataacttca
     2221 tgtaatagct tttcctcttc agctattcgt cgatacaaaa taactgcata aactggaaaa
     2281 actaaaacaa aagtcatata ggcatgactc aacaaggtca agccaatcaa ctcaggtaaa
     2341 atatttaaaa agtaattagg atgttttact gtcctaaaca agatatgatc tacatatttg
     2401 tgattattga caagcataag cttcactgtc caaatatctc ccaacaagtg aatcaccaac
     2461 atcaacatca gcatagaaaa aataagcaag actaaaccaa ccatgctcat accatcaaac
     2521 attgtcttat gcaccattgc ttcaacgagg caagagagat aaaaaacaat atgagccaac
     2581 gttaatcgtt ttgtattctc aactccaaat tctttcccgc cattgctaag gattcgtttc
     2641 tcattctcta tcgaacgctt taaaaaaatc aatcgaataa ggaatgttac taaaataatc
     2701 gctaatacca tattagtatc ctttctttta tctatatttt tatctatata aagaataata
     2761 cacttatgtt aaccctatgt gaactttaat aaaaaactaa tctgtctaca agctaatctt
     2821 aaattccata ccgtgttcat aagggagaaa actatagtcc atttgatagc tttctaaaat
     2881 attactcaca atgtaaagac ccaaaccgga actttcatcc ttatctgtca cgatttgaga
     2941 atgatagaat atatcaaata aatgttctag ttcttggtca cttagaggcg cacatgtatt
     3001 tttgatagag agatagccat cttgctcgga tatgattaca cgcccatttt tatctgaata
     3061 tttaattgca ttactaatca ggtttgtcaa aaccttatcc aatgccctaa gactcatgac
     3121 gaccctggta gcatctgtca attgattttc aattgtaaca cctattgaat gagctaattc
     3181 ttgataacgt gataaaatat ctactaaaac tggcttaaca gtcaaggtct cacgacactc
     3241 tgtccactct tggaatttag aagactccag tacttcttct aataagtggc tcatctggtc
     3301 aatcttattt atactctttg caatatattt tggatgatct ttgtaatctc caatattatg
     3361 ctgcatattc tctaggataa ttctaagact ggctaaaggg gttttcaact catgtgatgc
     3421 tccgcggaca aaggaaacct tttgattttg caattttaca atttgctcat tacgactttc
     3481 caactcatga ataaccttca acaagtgctc atacatacca ttaatctgtt ttccaacttc
     3541 accaacttca ccaacttcat ctttcctact ttcatcaaaa cgaatattgt catccaaatc
     3601 ttgcatttta ctagtcactt ctgaaatgta aaaaagagga ttgagcaagc gtttagtata
     3661 aaaataagaa aaaacaaagg aaaaagcaat tgtaaccaaa aatgtatatg ggagatacaa
     3721 aagcaaaata ttctttgctt ctttgtagac attcaccccg tgaacaaatt gcactgttac
     3781 ctgtttacca tctgctgtac taacagacat atctaacatc acgatgtaat ttgatagctt
     3841 tccatcttta atatccaagt catgcacaag agggagctgc ttatctacaa tatctctttt
     3901 aaggtgagca gatatggtca aggactttga ataagactgg agtaagcttg gaatttcatc
     3961 agatgtctta gtctttaaat actccgtaaa cactcttgcg ctctcattaa acttttcccc
     4021 ctccagttga atataataaa aaggaaaggt caaataaata gctatatgaa tgactagacc
     4081 aacaccacct agaattgcaa aacttcttaa aaaagacttg gttaataatt taggattttt
     4141 tatcataagc taatcttata cccaacattt ttcacagtca cgatacaatc taaagctaat
     4201 tttttgcgaa gagtacgaat atagacatca acgaccctat cacaaggtaa atcagctaca
     4261 tcttttgaaa tttcttccaa tatctgctct ctacttaaaa cttgattttt atgctgaatc
     4321 aaacacttta gtaccagtaa ttcctttggt ttgagatcaa tttcttcatt tttataatgt
     4381 gctttgtaag aggtaaaatc cactgttaca tcctgatatc gccaaagatc ctctatgacg
     4441 tagtaacgtc tgataagcgc cttaatacgc ttgacaagca gtaccaaaga aaaaggtttt
     4501 gtcacatgat catcagcata gagatcaaat acctgtgact gagtagtttc atctcccaga
     4561 gcactcaaga cgatgacagg aatatcgtgc ttttgattga tttcttttaa cacttcaaaa
     4621 ccactcttcc taggcatcat taaatccagt accatgagat ggatagggag atcttgaaat
     4681 ttttccaaga cctcttgtcc atccttagcc ataatgacat gataaccctc ttctgtcaga
     4741 aatgctgcaa ttccttctct aatcatttcc tcgtcatctg caactaaaat gttcatctct
     4801 ctccctttct actaccagaa ctccatacat ctatttcctg tatgctattt gaaaatttcc
     4861 taccagccta tcatctatga taatggaatg gatttcattt atccgctact ttttgtcaac
     4921 aacaacgtca atacaagaaa atcattcatc ttgcaactta tactcttcga aaatctcttc
     4981 aaaccacgtt agctctatct acaacctcaa aacagtgttt tgagcaacct gcggctagct
     5041 gcctagtttg ctctttgatt ttcattgagt ttcactccac tgtgacttat ggtcagatgc
     5101 tgatactttt attcttttat gcaatatcaa attttaactg gcctgctttg acaccaatct
     5161 taagtgtgct gcctgccact aaatctccct taagaagaag ttctgccaac ttgtcctcca
     5221 cttctgtttg cagggttctg cgaagtgggc gagctcccat ctctgggtca tatccttgat
     5281 ttgctaacaa tttcagagct gaagcttgta atttcaagtc aatgcctttt tcagccaaac
     5341 ttgccactaa aggcttgacc ataatcttca ccacttcctg catatggtca ctagataggc
     5401 tatggaagac caccttctca tcaatacggt tgatgaattc cggtctataa gcttttttca
     5461 gttcttcaaa catgcgtttt tccatatttt cctggtcaaa acgaatatcc ttagccccaa
     5521 aaccaacagt cttatcatca cgaagggcag tcgcacctag gttcgatgtc ataatgataa
     5581 tggtatttga aaaatcgacc ttgcgtccct tgctatctgt caagacaccg tcatccagaa
     5641 cctgcaagag aacattaaag atatctgggt gggccttctc tacctcatca aagaggagaa
     5701 cggaataggg tttattgcga accttctctg tcaactcccc accttcttcg taacccacat
     5761 agcctggagg agctccattt agacggctgg ctgcgaattt ctccatatac tcactcatat
     5821 caaagcggat aagggctgat tcttcatcaa agagaacttc tgccaaagct ttggccaact
     5881 cggtcttacc gacacctgta ggtcctagga acataaagga accgatcgga cgcttgtgac
     5941 tgcgaattcc tgactgatta cggcgaatcg cacgactaat gcttgaaaca gcttgatctt
     6001 gaccgataac ccgtttatgg agttctgctt caagatttag atacttctta gcatccgttt
     6061 gagtcagttt ttgaactggg attcctgaca agcgactcaa ggtggtcaaa atatcagact
     6121 ctgtcaccaa gtctttgtag acaggtactt cctcttcttt tgcgattagc tgggctgcct
     6181 gtttccactt gccatccatc agggccttgt cagctggact caaatctgaa tcgtctgctt
     6241 ttacatgctt tgccttattt tgcactgttg ctgctgcttc gtccaagagg tcgatagcag
     6301 agtctggcaa gtgacgactg gttaaataac gatgagccat cttaaccgct gtttcaaccg
     6361 cttcatctgt gatttgtaca cggtgatgtt tctcataagt cgccttcaaa ccttgtaaaa
     6421 tagtcatact atctgccaca cttggttctt caatcgtcac tttagcgaaa cgacgagaaa
     6481 gtgccgcatc tttttcgata tgtttttgat attcttcctg agtggtggca ccaaccgttc
     6541 tcaaagttcc acgcgccaag gctggtttca agatattggc cgcatccaga gtcgaatcaa
     6601 tcccgctacc agaacccatg atggtgtgga gttcatcgat aaagaggatg acttggccat
     6661 cttcttcaat atccttgatg atattattca tgcgttcttc aaagtcacca cggaagcgtg
     6721 tccctgcaac gacattcatc aaatcaagtt ctaacacgcg catcttagcc atttccgcag
     6781 gcacgtcacc actagcaata cgctgggcaa gaccaagggc cagagctgtt ttcccgacac
     6841 cagcatcccc aaccaagaca gggttgttct tagtcttacg gctcaagatt tgaatcatac
     6901 gtgagatttc cttgtcccga ccgatgactg gttctaactt gccagaatgc gcttgctctg
     6961 tcaaatcatg cgtatagtcc tcaagaccac cactaggagt ctgcggcatg cccatcatat
     7021 tggccataga attttgcttg tcagctactg tacgatggcg ttggcgtaaa gccttgagat
     7081 cttcacgagt ccagcctgcc cgttcttcta aatttcgacg aagggcagca atcttgacct
     7141 gatctttctt gtcttcataa gaaaaaccag ccctctccaa gatacgagtt gccaaggcat
     7201 tgccatcatg caaaatcgca tagaagacgt gctctgtccc tagcacctta gcatggacca
     7261 ctgacgctac atactctgct tcgtcaaaaa gaacctgcaa acgacgggag aacggcaatt
     7321 ccgtaaaggt ttcatcctgg ctatagtccg tttcagtcag ttccaaagcc acctcttcta
     7381 aacggtccat ctcatacgga taatcattta aagttgcccc tgctacacta taactgtgat
     7441 tagacatggc aatcaacaag tgccaagact ctagataacg agctccaaaa tgtccagcaa
     7501 ccatgtaggc actttcgata cattcattca atgcttttga atagttcatc ttacttccct
     7561 tttctatcta cctcttgtat gatctgacgt agcatgtttg ctcgaacaac tggagcttct
     7621 tctcctaaaa cgcgatccaa agctactgat tctagcaaat tcatctcctg cttggtcatc
     7681 aattcctgct caaccaaaag ctggagaata tcctcataaa tttcttgact gactcgctca
     7741 ccaatcgagt aaagcagctc ccggagcatt tcatgatgac tagaaaactc aatccgtcct
     7801 atacgaatgt agcctccgcc accacgctta ctttcaacca agtagcctct actttccgta
     7861 aagcgtgtct tgatcacgta gttaatctga ctaggaacaa cctgaaaggt atctgccaac
     7921 tgactccgtt gcaactccac gataccagat tgatctaaaa tcgccttgat gtaggcctca
     7981 atatgatccg atgtattttt aaatctcata acaaacccac ctctctcttt aaaccttgac
     8041 cttgtttgac tattataccg aaattttctc atttttaaaa gaaaaagggc gctggtaaag
     8101 gataatcttc accaactccc tatttttcta cttatctaag cctaattccg ccaaaatttg
     8161 acgtttgtag gcaatctttt ggacttcctt gtcctcatct tcagaccaat ctagtttaat
     8221 ttctgaaaca atctgcccag ggcgattttt caagatatag atgcggtcgc tgagattgag
     8281 ggcctcctca atactatgcg tgatgatcag ggttgttagc tgcaactgct tgtgaatctc
     8341 aagataccaa gcgtggagtt ccatctttgt catctcatcc aaggcgctaa aggcctcatc
     8401 taagagaaag agcttgtgcc caaaaaggta ggtccggagt aaggctacac gctggcgcat
     8461 cccaccgcta agttcatgag gatacttgtc tcttacagct gtcagctgga aggtcgcaag
     8521 aattttatcc gctcgggaaa tagcttctgc cttatccacc ttttgaatca agaggggcag
     8581 aatgatattt ccaagcaccg tcttgtgctc caagagcaga tccttttgca acatataact
     8641 cacgcgcccc ttgggatttt cttcaccatc aaggacaatt ctccctgact gaacttctaa
     8701 aatcccagcg attagattaa agagggtggt ctttccaaca ccacttgggc ctaggatgga
     8761 aaccacttcg cctgaagtca cctgtaggtt gatatcctct aaaatcctct cctgaccata
     8821 ggcataactg acgtgctcta gtctaatttc tgtcattatt tcacaaattc gttggtgaag
     8881 cctttgtctg tcaagtcttc tttaaggata ccattttctt tatcccattt gtagaaagca
     8941 ttccagcgag ctgcgtcaaa ttgaccccat ttttccttgt cgcttgcgta ttcttttgac
     9001 aagtattttt gagattcgat gacaaagtca cgtttttcct tgagttcagg tgcattcttg
     9061 atgagaatat ctgcagcttc ttctggatgt tccatggcat attggtagcc ttttttgatg
     9121 gcttggatga ctttgcgagc ttcttctttg ttatctttca gatagtcgtt gtttgcgatg
     9181 ataactggtg aatagtagtc aaactccttg acatagtctt tcaagtacat gaagttagca
     9241 tctacacctt gagatttagc aaggatacca tcccaaccgt agtaaatcca agcagtatca
     9301 aagacgccat tggcaatcgg tgtgattgag tttgagtcgt tatttggtac tttttcaacc
     9361 ttctcaaagt ctccaccttg agattctacc aaggttttca acatagcaag ttcagttggg
     9421 tcattccatg tcccatattt cttaccaacc aagtcttttg gactgcttac attatcagat
     9481 ttacgagaga tgattcctga tgtattgtgt tcaacaatag ctgcaacggc agtgattcct
     9541 gctccttttt ccaatttctt agccatgtag tcttggaaat acactgcaaa tggtgccttt
     9601 ccgttgataa ccaagtcaga agaactttct tctggtggca atttcaaatc aacatccact
     9661 ccagcttctt tgaaataacc tttttccttg gcaacataaa gccctgtgtg gttggtattt
     9721 ggtgtccagt ctaggataaa gtcaaccttc ttaagttctg cctctttgtt gtctttagaa
     9781 gcagttcctt gaccacaggc cacaagcaca acagctacaa gagctgttac aagcgttaaa
     9841 aacactttcc atgttttctt cattttgatt tcctcttttc tttttcaaaa acgctctatt
     9901 ttaagtacgt ttccatttaa tcacatattt ttcactgata tcgaccagct tcatacccaa
     9961 aagactgata atcgacacca gaataataat ggcaaacatg gtatcatact gaaacagttt
    10021 tttagactga atcatataaa caccaagacc ttcaaaacct cccaaccact cagataccac
    10081 agttgtgata aaggcgtagg agacactgac cctcagacct gcataaaagt aaggcaggct
    10141 aaccgggatt ttaaaatgcc acaggatttg ccaagggttt gctcgcatca gactaaacaa
    10201 agtcagcata tccttgtcac aatgcctaaa accgtccaaa atactaacga tgatgggaaa
    10261 ggttgttgtt aagataatca agacaatctt gggcaaaatc ccataaccta gccacaagac
    10321 caggatagga gctatggcaa tggtcggaat ggtctgaatg accaccatca tagggtaaat
    10381 caggtcattg agccaagtca aactatccat gagcacagcc ataagacagg caatcaaaac
    10441 tcccaaaatc agccccagta aagccactct caaggtcgcc cagctatggt gccagagaaa
    10501 ttctctgtca cgaacaaagg gctggagaat ttcaagaggt gtcggcagga taaacttggg
    10561 gagaagttta agaaaacctg ctaactgcca gattgacaat actccgagaa agcccaatag
    10621 actaatgtgt cgtctcagta tacttttcaa gtttctcatc aatacttaaa atctctccta
    10681 catttatttt gacattggca aagacattgt ctgcctcctg ccctgccact tccagcgctt
    10741 cttttagaat gcgcataagc tcatcaaact ccccttccaa gaccgtttca aatggtgtca
    10801 ctaccatcgt cacttcttga gtttgcagat aagcaatgac ctgatcaata acagctatcc
    10861 gatcaatccc ctgtgctagg ggtaaaactt gcaaggcaat gcttgctttc ataagaacct
    10921 cctcttctcg ttttcctttt aaaaaaaaga aaaaccttta ccatacatgg aaaaggtgca
    10981 aaattagact aagtatcgtt ccctccgctg gcattatcca gatcaggtgc ggtcgaagtt
    11041 taacacttcc tctcagactg tacacagact cccatatatt atatgtatat atgatagcgc
    11101 aaaataagaa aaatgtcaag gaaactgctt acagaaaaga gcaggaaatt tctcctactc
    11161 caattttcta tactcgttct ccatcactgt ttactctgta gccatccacc gtcgtattaa
    11221 cagctaaggc gcctgaagag taagaataat accacttacc agagacctgg taccagcctg
    11281 ttttcattgc ccctgaacta cccagataat accacgagcc attctccttt aaccatcctg
    11341 tctgcatttc accagataat ttcaaataat accagctaga accgtctttc agccatcctg
    11401 ttgatttaga accatttgat ttgaaatgat accaactacc atttattttc ttccaaccga
    11461 cagttgaact attattggat ccatagctag agatatttcc tgattgattc tgataatttt
    11521 gtgaagaagt cactccctct agctgtatat agcgacgact tccgttataa gccgtataac
    11581 tcaaccactt gtagccgtct ttttcgagaa tttgatcata atgaaccttc tctccaggat
    11641 aatagtaatc aatcacagtt gcactaacta ggggttcagt tttgatagca gacttggtct
    11701 taaaataatg agttccacct gttgaagaaa gaacagaatt acctagagga tttttattca
    11761 cagcctccaa ttgaacataa cgatagcttc cattataggc agtataactc aaccacttat
    11821 agccgtcttt ttcaagtatc tgatcataat gaaccttctc cccaggataa tagtaatcaa
    11881 tcacagttcc gctagctaga ggttcagttt taatagcaga cttggtctta aaataatgag
    11941 ttccgcctgt tgaagttgag gattgactat tcccaacact gccaccatcc aaatcttta
//
LOCUS       DAVLGK010000055        11995 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLGK010000055 DAVLGK010000000
VERSION     DAVLGK010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11995
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.056"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(147..1778)
                     /locus_tag="VXE01_001884"
     CDS             complement(147..1778)
                     /locus_tag="VXE01_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV0750742.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2071..7011
                     /locus_tag="VXE01_001885"
     CDS             2071..7011
                     /locus_tag="VXE01_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV0750743.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSRANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVATASETAEAASAAKPEEK
                     ASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTSDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVQAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EFNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKAAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7101..8297
                     /locus_tag="VXE01_001886"
     CDS             7101..8297
                     /locus_tag="VXE01_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV0750744.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8433..8960
                     /locus_tag="VXE01_001887"
     CDS             8433..8960
                     /locus_tag="VXE01_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0750745.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9037..9393
                     /gene="glnR"
                     /locus_tag="VXE01_001888"
     CDS             9037..9393
                     /gene="glnR"
                     /locus_tag="VXE01_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV0750746.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9430..10776
                     /gene="glnA"
                     /locus_tag="VXE01_001889"
     CDS             9430..10776
                     /gene="glnA"
                     /locus_tag="VXE01_001889"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV0750747.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10872..10991)
                     /locus_tag="VXE01_001890"
     CDS             complement(10872..10991)
                     /locus_tag="VXE01_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0750748.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11480..11995
                     /locus_tag="VXE01_001891"
                     /pseudo
     CDS             11480..11995
                     /locus_tag="VXE01_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3859 a         2192 c         2567 g         3377 t
ORIGIN      
        1 tctaacaatg ttttagaaat agaggtgtac tattctagtt tcaatatact atatatctgc
       61 agaatactct ttcagcttca ttcagcctag tcttgcttag gaaaaagtaa aaagccatcc
      121 aattatgatg gatagcttct tggttcttag atttgttctg caaaaacctt ttcagcaagg
      181 ttcatagcgt ggtctgatac acgagtgtag tgtgagatga tgtcgataaa gttgacccca
      241 gcttgtgttg aacattcgcc tttgttgagg cgtttgatgt gggtttttct gagaacacgt
      301 tctatcttat tgattgcttc atgacgttct acaagactgc gtgctttttc aatatcattg
      361 ttttccacac tatccagagc atctttgata aagtcactag tttggcggta aacttcctct
      421 aattctttca aggcggcatc agaaaattca acatttttcc gttgaagata gtcagtcaga
      481 ttgagtagag cctccgtgtg gtctccaatc cgttccaaat cacgggagga atcaaggata
      541 ttggtgagca cttcactttc tttttggctg agagcttcgc ttgaaagggc aatgagataa
      601 cgtgttaatt gctcatcgat ggtgttaatt gcttcttcgg ttttatgccc tttttcagca
      661 actttttcat ccaagtcaat gatgtactta taggaaaggt caaaggcttt agcagcgtag
      721 tttcctaagt gcaagagctc ttttttagca tttcctagag cgatagatgg ggcttgtttg
      781 atgaaatgtt catcaagata taagggttcg tatttgacaa cctcgtcctc tccaggaata
      841 atcttggtta caaagtaagc cagagctccg ataaatggaa attggacaat ggtgttggta
      901 atattaaagg ttccgtgagc aaaggcgatg gtcatttccg gtgctagatt tagcgtagct
      961 tcaaaccaat gaatcaggac agtaaaagga actagaaaaa taacgcagac aactgttccg
     1021 ataacgttga aggcaacatg agctcctgct acccgtttag ctgcaatatt agcccctaaa
     1081 gaggcaatga tggctgtaat ggttgtcccg atattgtcac caaatagaac tggcaaagct
     1141 ccctgtaggt caattagatt gccggcgtag aggttttgta aaatcccaat ggtagccgaa
     1201 gaagcttgaa ttagcaaggt caagccagta ccgacaaaga cacccaaaac aggattctta
     1261 cttagctcaa tcatatagtc cttaaagacc tgtaaatcct tgagtggagc cattgcgccg
     1321 ctcataagat tgagggcaaa aaagatacca ccgacaccaa agaggatgcg tccgatatta
     1381 ttgactgtcc gatttttcgt aaaaaagaga cagacggcac cgataaagag cataggtagg
     1441 gcatagttac ctaatttaaa accgatgaga aaggatgtga cagttgtccc aatattagca
     1501 cccatgacaa tcccgatagc ctgacgtaag gttaagagac cggcactgac caggccgact
     1561 gtgataactg ttacaccaga actagactga attagagcag tcatcccaat accaaccaga
     1621 actccaaaga aaggattact agtatatttg tcaatgtaaa aacgaaggcg atctccagca
     1681 gcttgttgca aaccgtctcc catggtcttg atactatata agaatagccc cagaccacct
     1741 aaaaagtgaa ataaaatttc ctgccaatta atggacattt ctttttcctc cgaaaaataa
     1801 tcgcggaata tctcctattc tattttaaag gataaaagta aatctaacaa gtgttaatgt
     1861 caagtttgta aaagaaaatt ataattgata agtgtattat ttttaagagt ttttaacctt
     1921 attttagatt tgtgaaaaca gctattgttt tttgtctaaa aatgttttag gataaaaatg
     1981 tgattatcat ggttctagag tttgataaaa aactacagaa tataaagcgc tttcttgaaa
     2041 acaacaaaat caatctttta ggaggagaaa atgaagaatc cattttttga aagacgttgt
     2101 cgttacagta ttcgtaagtt atcagtagga gcctgctcgc tgatgattgg tgctgtttta
     2161 tttgctggtc cagccttggc tgaagaaact gcagttcctg aaaatagcag agctaataca
     2221 gagcttgttt caggagagag tgagcattcg accaatgaag ctgataagca gaatgaaggg
     2281 gaacatgcta gagaaaacaa gctagaaaag gcagaaggag tagcgacagc atctgaaact
     2341 gcagaagcag ctagcgcagc taaaccagag gaaaaagcaa gtgaggtggt tgcagaaaca
     2401 ccatctgcag aagcaaaacc taagtctgac aaggaaacag aagcaaagcc cgaagcaact
     2461 aaccaagggg atgagtctaa gccagcagcc gaagctaata agactgaaaa agaagtccag
     2521 ccagatgtcc ctaaaaatac agaaaaaaca ttaaaaccaa aggaaatcaa atttaattct
     2581 tgggaagaat tgttaaaatg ggaaccaggt gctcgtgaag atgatgctat taaccgcgga
     2641 tctgttgtcc tcgcttcacg tcggacaggt catttagtca atgaaaaagc tagcaaggaa
     2701 gcaaaagttc aagccttatc aaacaccaat tctaaagcaa aagaccatgc ttctgttggt
     2761 ggagaagagt tcaaggccta tgcttttgac tattggcaat atctagattc aatggtcttc
     2821 tgggaaggtc tcgtaccaac tcctgacgtt attgatgcag gtcaccgtaa cggggttcct
     2881 gtatacggta cactcttctt caactggtct aatagtattg cagatcaaga aagatttgct
     2941 gaagctttga agcaagacgc agatggtagc ttcccaattg cccgtaaatt ggtagacatg
     3001 gccaagtatt atggctatga tggctatttc atcaaccaag aaacaactgg agatttggtt
     3061 aaacctcttg gagaaaagat gcgccagttt atgctctata gcaaggaata tgctgctaag
     3121 gtaaaccatc caatcaagta ttcttggtac gatgccatga cctataacta tggacgttac
     3181 catcaagatg gtttgggaga atacaactac caattcatgc aaccagaagg agataaggtt
     3241 ccggcagata acttctttgc taactttaac tgggataagg ctaaaaatga ttacactatt
     3301 gcaactgcca actggattgg tcgtaatcct tatgatgtat ttgcaggttt ggaattgcaa
     3361 cagggtggtt cctacaagac aaaggttaag tggaatgaca ttttagacga aaatgggaaa
     3421 ttgcgccttt ctcttggttt atttgcccca gataccatta caagtttagg aaaaactggt
     3481 gaagattatc ataaaaatga agatatcttc tttacaggtt atcaaggaga ccccactggc
     3541 caaaaaccag gtgacaaaga ttggtatggt attgctaacc tagttgcgga ccgtacgcca
     3601 gcggtaggta atacttttac tacttctttt aatacaggtc atggtaaaaa atggttcgta
     3661 gatggtaagg tttctaagga ttctgagtgg aattatcgtt cagtatcagg tgttcttcca
     3721 acatggcgct ggtggcagac ttcaacaggg gaaaaacttc gtgcagaata tgattttaca
     3781 gatgcctata atggcggaaa ttcccttaaa ttctctggtg atgtagccgg taagacagat
     3841 caggatgtga gactttattc tactaagtta gaagtaactg agaagaccaa acttcgtgtt
     3901 gcccacaagg gaggaaaagg ttctaaagtt tatatggcat tctctacaac ttcagactac
     3961 aaattcgatg atgcagatgc atggaaagag ctaacccttt ctgacaactg gacaaatgaa
     4021 gaatttgatc tcagctcact agcaggtaaa accatctatg cagtcaaact atttttcgag
     4081 catgaaggtg ctgtaaaaga ttatcagttc aacctaggac aattaactat ctcggacaat
     4141 caccaagagc cacaatcgcc gacaagcttt tctgtagtga aacaatctct taaaaatgcc
     4201 caagaagcgg aagcagttgt gcaatttaaa ggcaacaagg atgcagattt ctatgaagtt
     4261 tatgaaaaag atggagacag ctggaaatta ctaactggct catcttctac aactatttat
     4321 ctaccaaaag ttagccgctc agcaagtgct cagggtacaa ctcaagaact gaaggttgta
     4381 gcagtcggta aaaatggagt tcgttcagaa gctgcaacca caacctttga ttggggtatg
     4441 actgtaaaag ataccagcct accaaaacca ctagctgaaa atatcgttcc aggtgcaaca
     4501 gttattgata gtactttccc taagactgaa ggtggagaag gtattgaagg tatgttgaac
     4561 ggtaccatta ctagcttgtc agataaatgg tcttcagctc agttgagtgg tagtgtggat
     4621 attcgtttga ccaagccacg taccgttgtt agatgggtca tggatcatgc aggggctggt
     4681 ggtgagtctg ttaacgatgg cttgatgaac accaaagact ttgaccttta ttataaagat
     4741 gcagatggtg agtggaagct agctaaggaa gtccgtggca acaaagcaca cgtgacagat
     4801 atcactcttg ataaaccaat cactgctcaa gactggcgct tgaatgttgt cacttctgac
     4861 aatggaactc catggaaggc tattcgtatc tataactgga aaatgtatga aaagcttgat
     4921 actgagagtg tcaatattcc gatggccaag gctgcagccc gttctctagg caataacaag
     4981 gtacaagttg gctttgcaga tgtacaggct ggagcaacta ttaccgttta tgataatcca
     5041 aattctcaaa ctccgctcgc aaccttgaag agcgaagttg gaggagacct agcaagtgca
     5101 ccattggatt tgacaaatca atctggtctt ctttattatc gtacccagtt gccaggcaag
     5161 gaaattagta atgtcctagc agtttccgtt ccaaaagatg acagaagaat caagtcagtc
     5221 agcctagaaa caggacctaa gaaaacaagc tacgccgaag gggaggattt ggaccttaga
     5281 ggtggtgttc ttcgagttca gtatgaagga ggaactgagg acgaactcat tcgcctaact
     5341 cacgcaggtg tatcagtatc aggttttgat acgcatcata agggagaaca gaatcttact
     5401 ctccaatatt tgggacaacc ggtaaatgct aatttgtcag tgactgtcac tggccaagac
     5461 gaagcaagtc cgaaaactat tttgggaatt gaagtaagtc aggaaccgaa aaaagattac
     5521 ctagttggtg atagcttaga cttgtctgaa ggacgctttg cagtggctta tagcaatgac
     5581 accatggaag aacattcctt tactgatgag ggagttgaaa tttctggtta cgatgctcaa
     5641 aagactggtc gtcaaacctt gacgcttcgt taccaaggtc atgaattcaa ttttgatgtt
     5701 ttggtatctc caaaagcagc attgaacgat gagtacctca aacaaaaatt agcagaagtt
     5761 gaagctgcta agaacaaggt ggtctataac tttgcttcac cagaagtaaa agcagctttc
     5821 ttgaaagcaa ttgaagcggc cgaacaagtg ttgaaagacc atgaaactag cacccaagat
     5881 caagtcaatg accgacttaa taaattgaca gaagctcata aagctctgaa tggtcaagag
     5941 aaatttaagg aagaaaagac agaacttgat cgcttaacag gtgaggttca agaactcttg
     6001 gctgccaaac caaaccatcc ttcaggttct gccctagctc cgcttcttga gaaaaacaag
     6061 gccttggttg aaaaagtaga tttgagtcca gaagagcttg caacagcgaa acagagtcta
     6121 aaagatctgg ttgctttatt gaaagaagac aagccagcag tcttttctga tagtaaaaca
     6181 ggtgttgaag tacacttctc aaataaagag aagactgtca tcaagggttt gaaagtagag
     6241 cgtgttcaag caagtgctga agagaagaaa tactttgctg gagaagatgc tcatgtcttt
     6301 gaaatagaag gtttggatga aaaaggtcaa gatgttgatc tctcttacgc ttctattgtg
     6361 aaaatcccaa ttgaaaaaga taagaaagtt aagaaagtat ttttcttacc tgaaggcaaa
     6421 gaggcagtag aattggcttt tgaacaaacg gatagtcatg ttatctttac agcaccacac
     6481 tttactcatt atgcctttgt ttatgaatct gctgaaaaac cacaacctgc taaaccagca
     6541 ccacaaaaca aagtccttcc aaaacctact tatcaaccgg cttctgatca acaaaaggct
     6601 cctaaattgg aagttcaaga ggaaaaggtt gcctttcatc gtcaagagca tgaaaatact
     6661 gagatgctag ttggggaaca acgagtcatc atacagggac gagatggact gttaagacat
     6721 gtctttgaag ttgatgaaaa cggtcagcgt cgtcttcgtt caacagaagt catccaagaa
     6781 gcgattccag aaattgttga aattggaaca aaagtaaaaa cagtaccagc agtagtagct
     6841 acacaggaaa aaccagctca aaatacagca gttaaatcag aagaagcaag caaacaattg
     6901 ccaaatacag gaacagctga tgctaatgaa gccctaatag caggcttagc cagccttggt
     6961 cttgctagtt tagccttgac cttgagacgg aaaagagaag ataaagatta aatatcgaaa
     7021 aatcttgtga aatctttcct tatatttcca aagtgtgata taatagtttc gaataaaata
     7081 aataaaggag tttttgtaac atggcaaaac ttactgttaa agacgttgac ttgaaaggta
     7141 aaaaagtcct cgttcgtgtt gacttcaacg taccattgaa agatggcgta atcactaacg
     7201 ataaccgtat cacagcagct cttccaacta ttaagtacat catcgaacaa ggtggacgtg
     7261 caattctttt ctctcacctt ggacgtgtga aagaagaagc tgataaagct ggtaaatcac
     7321 ttgctcctgt agcagcagac ttggcagcaa aacttggtca agatgttgtt ttcccaggtg
     7381 tcactcgtgg tgctgaattg gaagcggcaa tcaacgctct tgaagatgga caagttctct
     7441 tggttgaaaa cactcgttac gaagatgttg acggcaagaa agaatctaaa aacgatcctg
     7501 aacttggtaa atactgggca tcacttggag atggtatctt cgtaaacgat gcattcggta
     7561 cagctcaccg tgcacacgca tctaacgttg gtatctcagc aaacgttgaa aaagcagttg
     7621 ctggtttcct tcttgaaaac gaaattgcct acatccaaga agcagttgaa actccagaac
     7681 gtccattcgt ggctatcctt ggtggttcaa aagtttcaga caagatcggt gttatcgaaa
     7741 acttgcttga aaaagctgat aaagtcctta tcggtggtgg gatgacttac acattctaca
     7801 aagcacaagg tatcgaaatc ggtaactcac ttgtagaaga agacaaattg gatgttgcga
     7861 aagctcttct tgaaaaagca aatggtaaat tgatcttgcc agttgactca aaagaagcta
     7921 acgcatttgc tggttacact gaagtgcgtg acactgaagg tgaagcagtt tctgaaggct
     7981 tccttggtct tgacatcggt ccaaaatcta tcgccaaatt tgacgaagct ttgactggtg
     8041 ccaaaacagt tgtatggaac ggacctatgg gtgtatttga aaacccagat ttccaagctg
     8101 gtacaatcgg tgtgatggac gctatcgtga aacaaccagg agttaaatca atcatcggtg
     8161 gtggtgactc agctgccgca gcgattaacc ttggccgtgc agacaagttc tcatggatta
     8221 gtacgggtgg tggagcatca atggaacttc ttgaaggtaa ggttcttcca ggacttgcag
     8281 ccttgacaga aaaataagat tttataaaca aatcaaagaa gagagggatg aaagttcctc
     8341 ttttcttttg cttaaaataa aaacgcttcc tctcaactat tactcataaa aatcaccgat
     8401 ttatgataaa atggaaatag aaagttgaga ttatgagtta ttttaaaaaa tataaattcg
     8461 ataaatccca gttcaaactt ggtatgcgaa cctttaaaac aggtattgct gtttttctag
     8521 ttctcttgat ttttggcttt tttggctgga aaggtcttca aattggtgct ttgacagccg
     8581 tttttagcct gagggagagt tttgatgaga gtgttcattt tgggacttcg cgtattctag
     8641 gaaatagtat cggtggactc tatgccttgg tcttcttctt attaaatact tttttccacg
     8701 aagccttttg ggtgaccttg gtagttgttc caatctgcac catgttaacc attatgacaa
     8761 atgtagccat gaataacaaa gcaggggtta ttggtggtgt agcagctatg ttaatcatta
     8821 ccctatcaat tccaagtggc gagacaattt tgtacgtgtt tgtgcgtgta ttagaaacgt
     8881 ttatgggagt ttttgtcgca attatcgtaa attacgatat tgatcgtatt cgtctctttt
     8941 tagagaaaaa agaaaaataa tgttacattt tataacatta tcaattgacg tttgtctttt
     9001 tttagactat aatagacaga aagaaggaaa ttgtaaatga aggaaaaaga atttcgccga
     9061 aatatggctg tttttcctat cggcagtgtt atgaagttga ccgatctatc ggcgcgtcag
     9121 attcgttatt atgaagatca agagttgatc aagcccgatc gaaacgaagg aaatcgtcgc
     9181 atgtattcct tgaatgacat ggatcgtctg cttgaaatca aagattatat ctctgaaggt
     9241 tataatatcg ctgccattaa gaaaaaatat gctgaacgtg aagcgaaatc caagaaagcg
     9301 gttagtcaga ctgaagtacg tcgtgcactt cacaatgaac tcctccaaca ggggcgtttt
     9361 gcttcagtac agtcaccttt tggtcgcggt taggcaaccg caagtagtca tagattaagg
     9421 agaaaactta tgccaatcac agctgcagat attcgtcgtg aagtcaagga aaaaaatgtt
     9481 acctttattc gtcttatgtt ctcagatatt ttgggaacca tgaaaaacgt cgaaattcct
     9541 gctacagatg aacagttaga taaggtcttg tcgaacaagg ttatgtttga tggatcttct
     9601 attgaaggtt ttgtacgtat caatgagtcg gatatgtact tgtatccgga cttggataca
     9661 tggacagtct tcccttgggg agatgaaaat ggaagtgttg caggtctgat ctgtgatgtc
     9721 tatacaacag aaggtgaacc atttgcgggt gaccctcgtg gtaatttgaa acgagctctt
     9781 cgtcacatgg aagaagttgg attcaaatcc ttcaaccttg gtccagagcc agaattcttc
     9841 ctatttaagt tggatgaaaa tggggaccca acacttgaag tgaatgacaa gggtggctac
     9901 tttgatttgg cacctactga ccttgcggac aacacacgtc gtgagattgt gaatgtcttg
     9961 accaaaatgg gatttgaagt agaagcgagt caccacgagg ttgcggttgg acagcatgag
    10021 attgacttta agtacgatga agttctccgt gcttgtgata agattcaaat ctttaagctt
    10081 gttgttaaaa ccattgctcg caaacacgga ctttacgcaa catttatggc gaagccaaaa
    10141 tttggtattg ctggatcagg tatgcactgt aatatgtcct tgtttgatgc agaaggaaat
    10201 aacgccttct ttgatccaaa tgatccaaaa ggaatgcagt tgtcagaaac agcttaccat
    10261 ttcctaggcg gtttgatcaa gcatgcttac aactatactg ccatcatgaa cccaacagtt
    10321 aactcataca aacgtttggt tccaggttat gaagcgcctg tttacattgc ttgggctggt
    10381 cgtaaccgtt cgccacttgt gcgcgtacct gcttcacgtg gtatgggaac tcgtcttgag
    10441 ttgcgttcag tggatccaat ggcgaaccct tacgttgcta tggctgttct tttggaagtt
    10501 ggtttgtatg gtattgaaaa taaaatcgaa gcaccagctc ctatcgaaga aaatatctac
    10561 atcatgacag cagaagagcg caaggaagct ggtattacag accttccatc aactcttcac
    10621 aacgctttga aagctttgac agaagatgaa gtggttaaag ctgctctcgg agatcacatc
    10681 tatactagct tccttgaagc caaacgaatc gaatgggcaa gttatgcaac cttcgtttca
    10741 caatgggaaa ttgataatta tttagacctt tactaatact aatatagaag aaagattgcc
    10801 tgtgggtaaa cagtcacaca gcagtctaag ccatcaaata cctataaccc ttaaaatagc
    10861 gatttcggtc gctatttatt tttcgaaaaa tcctcttgac tcttttgcga attagattta
    10921 tcatcagacg tgtagaagaa aattaaggag tcactatgga aaaattcaat ttcaaaaaca
    10981 atatcgggca agaaaacaag ttacttcaaa tcgaaatcta caagtttact aacttttaca
    11041 agcttcaaaa ttacacatct gtaaatattt tttcgaaaga tatatttgaa gccatagtaa
    11101 attgagacta gaatagtaca ctacatctgc taaaaatttc tagaaactaa tttaactttc
    11161 ctaatcgatt tgtttacatc ttatttcaat ctactatatt atctcaataa atgatgatgg
    11221 cgactgtttt gtttgtgctt gtcgattttt gaatccctga tcgagcggaa gaatatttct
    11281 gccgaggttg ccaaggggaa aatactgaag atattgaatt ttatgatgaa caattacagg
    11341 cagaaaaggt ggaggttttg aatattcgat tggaagtaaa aaattgaatt atctacaatc
    11401 tcatcaacaa taaacctatt tcaaccccat tatctatagg cgtattttta cgccttttta
    11461 tatacttgaa gcacataaga aacattatgg gaagtttgct gatggaagta ctcaagaaat
    11521 tgatgttcct tatgatattc ctgatacttg ggagtgggtg aggataaaat caatttattg
    11581 gaattttggg caaaataagc cagagaaatc ctttaggtat atagatacgt ctagtattga
    11641 tagaaaaaag aacataatca actacaaaaa tctacaatat ctttcacctg aacaagcgcc
    11701 ttcccgtgcc agaaaattag tttcgcagaa tagtgtctta ttttcaacag ttagaccata
    11761 tctaaaaaat attgctgtag ttagagaact taaagagtat ttgatagcta gtacagcatt
    11821 tattgttttg gatactttac ttaacgaaac atatttgaaa tattatttat tatcagataa
    11881 ttttatcaat cgtgttaata ataaatctac tggaacaagt tatcctgcaa tcaatgatta
    11941 taattttaat ctattattaa ttgctctccc cccactatcc gaacaacaac gaata
//
LOCUS       DAVLGK010000056        11589 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLGK010000056 DAVLGK010000000
VERSION     DAVLGK010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.057"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            436..1146
                     /gene="deoD"
                     /locus_tag="VXE01_001892"
     CDS             436..1146
                     /gene="deoD"
                     /locus_tag="VXE01_001892"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0750749.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1169..1693)
                     /locus_tag="VXE01_001893"
     CDS             complement(1169..1693)
                     /locus_tag="VXE01_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV0750750.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1746..1982)
                     /locus_tag="VXE01_001894"
     CDS             complement(1746..1982)
                     /locus_tag="VXE01_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV0750751.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(2050..2970)
                     /locus_tag="VXE01_001895"
     CDS             complement(2050..2970)
                     /locus_tag="VXE01_001895"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV0750752.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEIYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3160..3564
                     /locus_tag="VXE01_001896"
     CDS             3160..3564
                     /locus_tag="VXE01_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750753.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLMIKHLKVKQ"
     gene            3780..4361
                     /locus_tag="VXE01_001897"
     CDS             3780..4361
                     /locus_tag="VXE01_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0750754.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4358..5635
                     /locus_tag="VXE01_001898"
     CDS             4358..5635
                     /locus_tag="VXE01_001898"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV0750755.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLEDGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5653..6315
                     /gene="deoC"
                     /locus_tag="VXE01_001899"
     CDS             5653..6315
                     /gene="deoC"
                     /locus_tag="VXE01_001899"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV0750756.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDISAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6302..6691
                     /locus_tag="VXE01_001900"
     CDS             6302..6691
                     /locus_tag="VXE01_001900"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0750757.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6782..7834
                     /locus_tag="VXE01_001901"
     CDS             6782..7834
                     /locus_tag="VXE01_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV0750758.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7978..9513
                     /locus_tag="VXE01_001902"
     CDS             7978..9513
                     /locus_tag="VXE01_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750759.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SIGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            9506..10564
                     /locus_tag="VXE01_001903"
     CDS             9506..10564
                     /locus_tag="VXE01_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0750760.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10567..11523
                     /locus_tag="VXE01_001904"
     CDS             10567..11523
                     /locus_tag="VXE01_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0750761.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         3300 a         2070 c         2656 g         3563 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa agaaaggaat tgaccccacc
      181 ctaaaagcag tgggaaaaag atagttggtc tagcgagcat cgctcactgc gcccaactcc
      241 tattttccct tcgctttttg acgggtttgg tatctttctc aatataaaat ataaaataaa
      301 gaaaggtaga gcgtgtgttt tgatttgaac acgagcggaa aactcggaaa atagataatc
      361 tgactgaaaa atcaggattt ctcgtcggct tcctaatttt cagtcgtttt cttctcgctc
      421 tttgtatcat aaattatgtc tatccatatt gctgctcagc agggtgaaat tgctgataaa
      481 attcttcttc ctggggatcc tcttcgtgct aagtttattg cggagaattt ccttgatgat
      541 gctgtttgtt ttaacgaagt gcgtaacatg tttggttaca ctggtactta caagggtcac
      601 cgtgtatctg tcatgggaac tgggatggga atgccatcta tttcgattta tgcgcgtgag
      661 ttaatcgtag actacggtgt gaagaaattg attcgtgtgg gaactgcagg ttctttgaat
      721 gaagaggttc atgttcgtga attagttttg gcgcaggcgg ctgcaaccaa ctcaaacatc
      781 gttcgtaatg actggccaca gtacgatttt ccacaaattg ctagctttga tttgcttgat
      841 aaagcctacc atatcgccaa agaacttggt atgactactc acgttgggaa cgttttgtca
      901 tctgatgtct tttactcaaa ttactttgaa aagaatatcg agcttggtaa atggggagtc
      961 aaggctgtgg aaatggaagc agcagctctt tactatcttg ctgcccaata ccatgttgat
     1021 gcgctagcta tcatgaccat ctctgatagc ttggtcaatc cagacgaaga cacaactgca
     1081 gaagaacgtc aaaatacctt cactgatatg atgaaggttg gtttggaaac cttgattgca
     1141 gaataattat agccaaaaag gaagcccttt atgaattgta ggacttcctt ttcttatcca
     1201 gaaattgatc tagctctctc tgatttcgaa gaatagtgac tttatgtgaa tattcttggc
     1261 aaagtttttg gtaattttct ttttgagttt tgctacgccc atcccaaaga atccatctga
     1321 taaactccca ctcaaagcgt tcagggcaat ctgccgccat actttctctg acttttccac
     1381 ggtatttaag ataacgctta aaggctctaa agagacaggt caatggcaaa aaattgagaa
     1441 agatgatttg gtcagcttct tgcattcgtt cttggtagta gcaccaagaa taattaccat
     1501 cgatgaccca agctttatgc ttggtgagaa agttttttat ctcggttaac atccattcgc
     1561 agtcactgtc ttgccaacca ggttgaaatt ggagtgtgtc catgtgcagt tttggaatgg
     1621 agtagtagtt agataacttt tctgctagag ttgacttacc agaaccagaa tatccgataa
     1681 ttgcgatttt cattttctac cttttcctat ttggagacaa aaaaacagcc tctatggact
     1741 gtttcttatt tagcaagttt agctgaaaga cgagctttat cgcggcttgc tttgtttttg
     1801 tgaatcaaac ctttagtttc tgctttatcg atagctgagc tagcagcacg gaaaagttct
     1861 tcagatgggt ttgcttcgaa agcttttata gcagtacgca tagctgattt ttgagctgag
     1921 ttcttttcgt tttgtttaac gttcaattca gcgcgtttga tagctgattt aatgtttgcc
     1981 aatgttctta cctccatatt tactaactat accattatat atgaaaactt acgttttgac
     2041 aagggaaaat tactttttta agtaaatttc atcgatttca tggttcttgc ttttatgaag
     2101 aatcacttct gcacgatttc tggttggttc aatataattt tgcagatttg tgagattgat
     2161 actgatccag acctgatggg caaaggactc tacttcccca atcggcatct gagtaaaacg
     2221 ataatagtag ctatcagggt cgttttgggc taggctcagc attttcaaga aacggtccag
     2281 ataccaactt tcaatatcat ccactccagc atctacatag atggaaaagt caaagaagtc
     2341 agtgatatag agacgatcgt tttgtggatt ttgaaagaca ttgattccct caacaattac
     2401 aaaatcagca gctttgacac tttgtttctc ttcgggtacg atgtcgtaaa tttcatgaga
     2461 atagacagga atatctacat cttgtccatt tttgatgcgg tccaagaagt tgagaagagc
     2521 ttccatatca tagctttcag gaaatccttt acgatttaaa atcccctgct caatcaaggt
     2581 ttgattggga tagagaaaac catcagttgt aaccaactca accgtagcat ctgtaaacgt
     2641 acgggacagt aggatttgaa gtaggcgact ggttgtggat tttccaacgg caacactccc
     2701 agaaacccca ataataaaag gttgagattt actttcacgt tggaggaaaa ttccttttga
     2761 aaaggctaaa tcttccttag ttcgcttgta aatctgaatc agatgagcca aggggagata
     2821 gatatctgta acgtcttgga gactgatttg gtcattaaaa ctcttgatag attccaattc
     2881 ttcttctgtc aaaggaggtg ttgtttttcg atgtaaagat tgccaagtct ggcggctgat
     2941 tttttcaaaa tgtaaaaatt cgttggtcat ttgttttccc ctagatattt tgtctatcat
     3001 accataaaaa gctaaaaaaa taaagcggtt tcttgaatgt ggtaagtcaa tggtatataa
     3061 tataagtgat caatttattg atgaaatagg aggtagattc tactgattta taagcttata
     3121 aagggggctt tttagttcac aacttatagg aggtgtacta tgaaaatctt aaaacgttac
     3181 atattggaac tctgttttat tttaagtttt gctttacctt ttataaaagg agccaatgca
     3241 gataatggta tatgctttgt ggaaacctat tacggtttta cttttttgat ggaacatgct
     3301 attgtaacag ctgtctttat ctattcgttt ttaattgctt tcttactaaa aaaacgatgg
     3361 gcgaaatgga ttgctgctgg tagttattgc tttttagtcc tatggattgc gacagagggt
     3421 tatttcttcc gcatgtcact agaagatttg atacgacttt ggacaagttt ggaaatcctg
     3481 acacaaacgt atcagttggg cttttatcta aatattttgt taggaatttt gttgatgatt
     3541 aagcatttga aggttaagca atagtaatca aaatgcgcct gatgatagac aataaacttt
     3601 ttgtttttat ctggactgtg atatttatag ttctaaatgg tttattattt ataagtgttg
     3661 aaagagattg aagaaaatgg cttcgtgact cgctttcttc ggtctttttc gttttattat
     3721 caatttgtaa acgatttaca atttgagtca aattatggta aaatagtgtc atgagtaaaa
     3781 tgtattatgc agaaaatcct gacgctgctc acgacattca tgagttgaga gtagagttgt
     3841 tgggacaaaa aatgaccttt ttgacggatg cgggtgtttt tagcaagaaa atagttgact
     3901 ttggaagtca actcttgctc aagtgtctgg atgtcaacca aggagagaca gtcctagatg
     3961 taggctgtgg ttatggtcca ttaggtttgt ccttggtcaa ggtttacgga gttcaggcga
     4021 ccatggttga tattaacact cgtgccctgg atttagctca gagaaatgct gaaaaaaata
     4081 atgcaaaagc gacgatattt caatctaata tttatgcaag agttcaaggg cgatttgacc
     4141 atgtcatttc caatcctcct atccgtgcgg gcaagcaagt cgttcatgaa atcatcgaga
     4201 aaagtaaaga tttcttggaa actggtgggg atttgacaat cgtcatccag aaaaaacaag
     4261 gggctccaag tgctaagtcc aagatggagg atgtgtttgg taattgtgaa atccttaaaa
     4321 aagacaaggg atactatatc cttagaagtg tgaaagaatg agagcagttg atttaataca
     4381 aaaaaaacga gacggtcaag aactgacttc aagtgaaatt gaatggctgg tagaaggcta
     4441 tgtgtcagga actgttcctg attatcagat gtctgccttt gctatggctg tttattttaa
     4501 aggaatgacg actcgtgaaa tttctgattt aacgatgaat atggttaaga ctgggcaaga
     4561 gtttgacctg tcagccattg atggtgtgaa agttgacaag cattctactg gtggtgtcgg
     4621 cgataaggta accttgattc tagctcctct tgttgctagc ttcggtgtgc ctgtagcaaa
     4681 aatgagtggt cgtggtcttg gccatacagg cggaacaatt gataaattgg agtccattaa
     4741 gggctatcaa gtagaacgta gtcaagagga ttttattcgt caggttcagg atattggagt
     4801 atctgtcatt gggcaatcag accagctggt caaagcagat aagcttctct atgcccttcg
     4861 tgatgtgacc gcaactgtcg acacgattcc tttgattgcg agttcggtga tgagcaagaa
     4921 aattgcggca ggggcggatg ctattttgct agacgtgact gtcggtgagg gtgccttcat
     4981 gaagacggtt gatgaggcgc gtgagttggc tcaaactatg gtagatcttg gtaaggttgt
     5041 tggacggaag acagtagcag tgattacgga tatgagccag cctttgggac gagcgattgg
     5101 aaatcgtctg gaaatccttg aagcattgga gattttgcaa ggtcaaggac gtcaggatat
     5161 tacccacttt atttgtgaat tggctcaaat tatgcttggc ttggcaaatg ttaacaagac
     5221 tgttgaagaa gttcgccaac atcttgagga tggtcaagca ctggctaagt ttgaggaaat
     5281 ggtgcaagcc caaggtggag acttggaaga cctctatcgt cctgtaaatg tagctcatgt
     5341 ggtggaaatc cctgctcagg aaacgggtgt catttcagct cttccagcta tggactttgg
     5401 tctttatgcc atgaggctgg gtgctggtcg tgcagttaag tctgatgcct tggactatga
     5461 aacaggaatt gtttttgaaa agaagattgg agactccgtt caaaagggtg aaattgttgc
     5521 aaaagtatac acaaatgaaa aaattccacc tcaactagtt acagatttcc aaaaatgtgt
     5581 taaaataagt gatgaagtga aaaaaatccg tgaaattgta gaaatcatct cctaaatgga
     5641 gggaaaaccg aaatgaaatt aaataaatat atagatcata cgcttttaaa acaagatgca
     5701 aagaaaaaac aaattgatag tttgttgtct gaggctagag agtatggctt tgccagtgtt
     5761 tgcgttaatc caacctgggt tgaacatgct aaaaaagggc ttgaaggcac agatgttaag
     5821 gtttgcacgg tagtaggttt ccctttggga gcaacaactt cagccgtgaa agcatttgag
     5881 acaaaagaag ctatccaaaa tggtgcagat gagattgata tggtgatcaa tgttggagct
     5941 ctcaaatcag gtaatttagc cttggttgag tcagatatta gcgcagtagt ggaagcaagt
     6001 ggtgataagt tagtgaaagt cattattgaa gcttgccttc tgacagacca agaaaaagtt
     6061 gttgtttgcc aattggccca aaaagctggg gctgactttg tcaaaacatc tactggcttt
     6121 tcaactggtg gtgctacgat agcagatgtt acattaatgc gtgaaacagt tggatctgat
     6181 atgggagtca aggctgctgg tggagctcgt tcttatgcag atgctcttgc ctttgtcgaa
     6241 gcaggtgcga cccgtatcgg aacgtcagct ggggtagcta ttttaaaagg agaattggca
     6301 gatggcgact actgagttga ttgaactggc aattgaaacc agcaaacatg cctatgtccc
     6361 ctattctcac tttcctatcg gagcagtttt agtagccaaa gacggaaatg tttacacggg
     6421 agtgaatatc gaaaatgcta gctatccttt gaccaattgc ggtgagagaa cagctatttt
     6481 taaggctata tctgaaggcc aaagagaatt ttcagaattg attgtctatg gtcaaactga
     6541 aaaaccgatt tcaccatgtg gtgcttgtcg ccaagtaatg gtcgaatttt ttgaacaaga
     6601 tttaaaagtg accttagtcg caaaagataa atcgacggtc gagatgacgg tcggggagtt
     6661 acttccatat tcttttacag acttaaatta gtctgagtcg ctctttgagt ggcaagggtc
     6721 tttgtgacca atcaatccat acttgcaaca tcgttgcaca tcttatttag gaggttcagt
     6781 aatgaacaag aaacaatggc taggtcttgg cctagttgca gtggcagcag ttggacttgc
     6841 tgcatgtggt aaccgctctt ctcgtaacgc agcttcatct tctgatgtga agacaaaagc
     6901 agcaatcgtc actgatactg gtggtgttga tgacaaatca ttcaaccaat cagcttggga
     6961 aggtttgcag gcttggggta aagaacacaa tctttcaaaa gataacggtt tcacttactt
     7021 ccaatcaaca agtgaagctg actacgctaa caacttgcaa caagcggctg gaagttacaa
     7081 cctaatcttt ggtgttggtt ttgcccttca caatgcagtt gaagaagcag ctaaagaaca
     7141 cactgacttg aactatgtct tgattgatga tgtgattaaa gaccaaaaga atgttgcgag
     7201 cgtaactttc gctgataatg agtcaggtta ccttgcaggt gtggctgcag caaaaacaac
     7261 taagacaaaa caagttggtt ttgtaggtgg tatcgaatct gaagttatct ctcgttttga
     7321 agcaggattc aaggctggtg ttgcgtcagt agacccatct atcaaagtcc aagttgacta
     7381 cgctggttca tttggtgatg cggctaaagg taaaacaatt gcagccgcac aatacgcagc
     7441 cggtgcagat attgtttacc aagtagctgg tggtacaggt gcaggtgtct ttgcagaggc
     7501 aaaatctctc aacgaaagcc gtcctgaaaa tgaaaaagtt tgggttatcg gtgttgaccg
     7561 tgaccaagaa gcagaaggta aatacacttc taaagatggc aaagaatcaa actttgttct
     7621 tgtatctact ttgaaacaag ttggtacaac tgtaaaagat atttctaaca aggcagaaaa
     7681 aggagaattc cctggcggtc aagtgatcgt ttactcattg aaggataaag gggttgactt
     7741 ggcagtaaca aacctttcag aagaaggtaa aaaagctgtc gaagatgcaa aagctaaaat
     7801 ccttgatgga agcgtaaaag ttcctgaaaa ataatggatg gaagtcattt cttaggaagc
     7861 ggccaagggc cgctttttta agagttgaga caaagtcatt ttgtctcagt aaagcttgct
     7921 actagacaaa ctagcaagtt ttattgaaat aaaataagac tctgaaagga agagcacatg
     7981 gcacacgaaa atgtcattga gatgcgtgat attaccaagg tgtttggtgg atttgttgcc
     8041 aacgacaaaa tcaacttgca cctacgaaaa ggtgaaattc atgcactttt aggagaaaat
     8101 ggggctggta agtccacgct aatgaacatg ttagcaggcc ttcttgaacc aactagtggt
     8161 gaaatcgcgg tcaacggtca agttgtcaat ctcgactccc catctaaagc agctagcttg
     8221 ggaatcggga tggttcacca gcactttatg ttggttgaag ccttcacagt ggctgaaaac
     8281 atcattttag gtagtgaatt gactaaaaat ggtgtgctag atatcgctgg agctagcaaa
     8341 gaaatcaagg ctctttctga acgttatggc ttagctgttg acccttctgc caaggtagca
     8401 gatatctcag ttggagccca acaacgtgta gaaattttaa aaacacttta taggggggct
     8461 gatatcctta tctttgacga accaacggct gttttgactc catcagaaat tgatgagttg
     8521 atggctatta tgaaaaatct tgtcaaagaa ggaaaatcaa ttatcttgat tacccacaaa
     8581 ttggatgaaa ttcgcgcagt ttctgaccgt gttacagtta tccgtcgtgg gaaatcaatt
     8641 gaaaccgttg aaattgcagg ggctaccaat gctgatttgg cggaaatgat ggtaggacgt
     8701 tctgtttcct ttaaaacaga gaagcaagcc tctaaaccaa aagaagtggt tttgtctatc
     8761 aaagatttgg tggtcaatga aaaccgtggt gttccagctg ttaaaaatct gtccttggat
     8821 gttcgtgctg gagagattgt tggtattgcg gggattgatg gaaatggtca gtctgaactg
     8881 attcaagcca ttacaggtct tcgtaaggtt gaatctggta gcattgagct aaaaggagat
     8941 tcaattgtag gcttgcaccc acgtcagatt acagaactaa gtattgggca cgttccagaa
     9001 gaccgtcacc gtgatggctt gattttggaa atgatgatat ctgaaaatat tgcccttcaa
     9061 acctactata aagaaccaca tagtaaaaat ggaattttga attattcaaa tattacttct
     9121 tatgctaaaa agctgatgga agagtttgat gttcgcgctg ccagtgaatt agttcctgca
     9181 gctgcactct caggaggaaa tcaacaaaaa gcaattattg ctcgtgaaat tgatcgagat
     9241 cctgatctcc ttatcgttag ccagccaact cgtgggttgg atgtcggtgc cattgagtat
     9301 atccacaaac gcttgattga agagcgtgat aatggcaagg ctgtccttgt tgtcagcttt
     9361 gaattggatg agattttaaa cgtctcagac cgtattgccg ttatccacga tggtaagatt
     9421 caaggtattg tatcaccaga aacaaccaat aaacaagaac ttggtgtctt gatggctggt
     9481 ggaaacttgg gaaaggagaa gagtgatgtc taaaaaatta caacaaattt cggttccctt
     9541 gatttctgta tttctaggaa ttttactcgg agccattgtc atgtggatct tcggttatga
     9601 tgctatttgg ggctacgaag aattgttcta tacagccttt ggcagtctgc gtgggattgg
     9661 agaaatcttc cgtgctatgg gtcctctggt cttgattggt cttggttttg cggttgccag
     9721 tcgagctggt ttctttaacg tcggacttcc tggtcaggct ttggcaggtt ggattctcag
     9781 tggttggttt gccctgtcgc atccagatat gccccgtccc ttgatgattc tagcaaccat
     9841 cgtgattgcc ttgattgctg gtgggattgt cggagcgatt ccaggtattc ttagggccta
     9901 tctagggacg tcagaggtta ttgtaaccat catgatgaac tacattgtct tgtatgtagg
     9961 gaatgccttt atccatgctt tccctaaaga cttcatgcaa agtacagatt cgaccattcg
    10021 tgttggggct aatgcaacct atcagacacc ttggttggct gagttgactg gtaactcacg
    10081 gatgaatatt ggtattttct ttgccatcat tgccgttgca gttatttggt tcatgctcaa
    10141 gaaaacaact cttggttttg aaatccgtgc agttggtctt aatccacatg cttcagaata
    10201 tgctggtatt tctgccaagc ggactattat cctatctatg attatttcag gtgccttggc
    10261 aggtcttggt ggagctgttg aaggtttggg aaccttccag aacgtctatg ttcaaggttc
    10321 gtcattagct atcggattta acggaatggc ggttagtttg cttgcggcca actcaccaat
    10381 tggtatactt tttgcagcct tcctatttgg cgttctccaa gttggggctc ctggtatgaa
    10441 tgcggcgcag gtaccatctg agcttgtcag cattgtaaca gcgtctatta tcttctttgt
    10501 cagtgttcat taccttatcg aacgctttgt caaaccgaaa aaacaagtta aaggaggtaa
    10561 gtaaagatgt ctattataac cttgctcccc ctcttggtgt cttctatgct gatttactca
    10621 gcacctctca tctttacaag tatcggtggt gttttctctg aacgtggtgg tgtggtaaac
    10681 gttggccttg aaggaattat ggttatgggt gccttttctg gagttgtctt taaccttgaa
    10741 tttgcagaac aatttggagc agcaactcca tggctatcct tgcttgtagc aggattggtt
    10801 ggtagtgttt tctctatcat ccacgcagca gcgacggttc atttccgtgc agaccatgtt
    10861 gtcagcggta cggtattgaa cttgatggcg cctgccttgg ctgttttctt agttaaagtt
    10921 ctttataaca aaggacaaac cgacaaccta agtcaaactt ttggacgctt tgatttccca
    10981 gtcttggcaa atatcccagt gattggtgat atcttcttca agtcaactag tctacttggt
    11041 tatctggcga ttgccttctc attccttgct tggtttattc tctttaagac tcaatttggt
    11101 cttcgtctcc gctctgtcgg tgaacatcct caagcagcgg ataccttggg aatcaacgtc
    11161 tacaagatga gatatttagg gattattatt tcaggttttc taggtggaat tggcggagcg
    11221 atttatgcgc aatcaatctc agttaacttc tcagtgacaa ctattgttgg acctggattt
    11281 atcgcccttg ctgcgatgat ctttgggaaa tggaatccaa tcggtgctat gctttctagt
    11341 ctcttctttg gactttcaca aagtttggct gttatcggtt ctcaattgcc gttcctacaa
    11401 ggagtgccag cggtttatct tcaaattgca ccttatgttt tgacaattct tgtcttagca
    11461 gccttctttg gaaaagcagt cgcaccaaaa gcagatggta tcaactacat caaatcaaaa
    11521 taagcataca aaaaaacgtc agtccaatga ctgaactacc ccccaaaagt tagacagaaa
    11581 aaatctaac
//
LOCUS       DAVLGK010000057        11325 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLGK010000057 DAVLGK010000000
VERSION     DAVLGK010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11325
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.058"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            613..1605
                     /locus_tag="VXE01_001905"
     CDS             613..1605
                     /locus_tag="VXE01_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0750762.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1607..2425
                     /locus_tag="VXE01_001906"
     CDS             1607..2425
                     /locus_tag="VXE01_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV0750763.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2427..3212
                     /locus_tag="VXE01_001907"
     CDS             2427..3212
                     /locus_tag="VXE01_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0750764.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3310..3528
                     /locus_tag="VXE01_001908"
     CDS             3310..3528
                     /locus_tag="VXE01_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV0750765.1"
                     /translation="MKDLPEWFGIPESTQTYIEGTTTLQVWTAYQESDLTGFVSLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3513..3710
                     /locus_tag="VXE01_001909"
     CDS             3513..3710
                     /locus_tag="VXE01_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0750766.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            4443..10859
                     /locus_tag="VXE01_001910"
     CDS             4443..10859
                     /locus_tag="VXE01_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0750767.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPHEVVLADTSNSEDALSISDKEKV
                     AENKEKHENIHSAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKEDSNQS
                     QGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTYDRIFN
                     GSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFGK
                     NFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFN
                     YYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSYK
                     MYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAGI
                     PMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFDK
                     VNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIA
                     VMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQVF
                     SISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEI
                     DFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKSTY
                     GYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTARP
                     MMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLKE
                     IKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVPE
                     IHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEMEA
                     LNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIPG
                     TLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIAN
                     IYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHFI
                     RGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQF
                     EPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTYH
                     KVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQG
                     RNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDASSNFTKIHRIKFADQADEKGMISYY
                     LVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEGEASLEI
                     NKTISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAYDDGSA
                     LQYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEIKATKY
                     DSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKETKAEYP
                     YVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVT
                     TYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLMS
                     ALDGFNIIRYQVFTFKMNDKGEAVDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEAI
                     KEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNE
                     SVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQ
                     TGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDG
                     EIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSEL
                     KPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYVI
                     NLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDHS
                     QKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLGL
                     KKKNQD"
BASE COUNT         3941 a         1714 c         2278 g         3392 t
ORIGIN      
        1 tacgagatga tgaaagcctt aagtgttatt ttataaaggt tatttcaagt cgttccaagg
       61 taacaagtct agatcagatt gaagctgata aaacgataca aagaaaatat tcaagtgagc
      121 taaaaaaatt tattggattt tataatgaga ttatttgtga ggaaaatagt ttcctacatg
      181 tacgaaagag gtggtcgagt tggtttaggt agtcgatgcg tgagttgata attctcaggg
      241 tatggacttc tttttcatga atgaggtaaa agagcaggta ttgtttagag acaatcattc
      301 tgagcatatt ttctggatag aggaagtatc cgattttatg atcaaagtta ataccgccct
      361 ctggtgagaa gatgagtagg ttggtaattt aaactattaa acagaatttt tgattaaaag
      421 tattatttta tgagagaaat cctaatttca caatccatag gcaaactctt gcatttcgtt
      481 ttttattgga ctataatagg ttggtataaa gccttttgta gtaataaaat gtagaaggtg
      541 tagaaagcaa ggatttagaa tatttgtagt taaaaacaca atgttgctat tccttacgat
      601 agggagatag atatggcaat gatagaagtg gaacatcttc agaaaaattt tgtgaagact
      661 gttaaggaac cgggcttgaa gggggctttg cgctccttta ttcatcctga aaagcagacc
      721 tttgaagcgg tcaaggattt gacctttgag gttccaaaag ggcagatttt aggatttatc
      781 ggggcaaatg gtgctgggaa gtcgacaacc attaaaatgc tgacaggaat tttgaaacca
      841 acatctggtt tttgtcggat taacggcaag attccccagg acaatcggca agattatgtc
      901 aaagatattg gcgtagtctt tggacaacgc acccagctat ggtgggattt ggctctgcaa
      961 gagacctaca ctgtcttaaa agagatttat gatgtgccag actcgctctt tcataagcgt
     1021 atggactttt tgaatgaagt cttggatttg aaggacttta tcaaggatcc cgtgcggact
     1081 ctttcactgg gacaacggat gcgggcggat attgcggcct ccttgctcca caatcccaag
     1141 gttctttttt tagatgagcc gaccattggt ttggacgttt cggttaagga taatattcgt
     1201 cgggcaatta ctcagatcaa tcaagaggaa gaaactacca ttcttttgac cactcacgat
     1261 ttgagtgata ttgagcaact ttgtgatcgg attttcatga ttgacaaggg gcaagagatt
     1321 tttgatggaa cggtgagcca actcaaggag acctttggta agatgaagac tctctctttt
     1381 gaactgctac caggtcaaag tcatctcgtc tctcactatg aaggtctgtc tgatatgacc
     1441 attgatagac aaggaaacag cctcaacatt gaatttgata gttctcgcta ccagtcagct
     1501 gacattatca agcaaaccct gtctgatttt gaaatccgcg atttgaagat ggtggatacg
     1561 gatattgagg atattatccg tcgcttctac cgaaaggagc tctaggatga tcaaattgtg
     1621 gagacgttat aaacccttta tcaatgcagg ggttcaggag ttgattactt accgagtcaa
     1681 ctttattctc tatcggattg gcgatgtcat gggggctttt gtggcctttt atctctggaa
     1741 ggctgtcttt gattcttcgc aagagtcttt gattcagggc ttcagtatgg cggatatcac
     1801 cctctacatc atcatgagtt ttgtgaccaa tcttctgact agatccgatt cgtcctttat
     1861 gattggggag gaggtcaagg atggctccat tatcatgcgt ttgttgcgac cagtgcattt
     1921 tgcggcctcc tatcttttca ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg
     1981 ccttccattt ttaagtgtca ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga
     2041 ggtgctagga ttaactgtcc tttatctttt tagcttaacg ctcgcctatc tgattaactt
     2101 tttctttaat atttgctttg gattttcagc ctttgtgttt aaaaatcttt ggggttccaa
     2161 cctacttaag acttccatag tggcttttat gtcggggagt ttgattccct tggcattctt
     2221 tccaaaggtt gtttcagata ttctttcctt tttgcctttt tcatccttga tttatactcc
     2281 agttatgatc attgttggaa aatacgatgc cagtcagatt cttcaggcac tccttttgca
     2341 gttcttctgg ctcttagtga tggtgggatt gtctcagttg atttggaaac gggtccagtc
     2401 ctttatcacc attcaaggag gttagtatga aaaaatatca acgaatgcat ctgattttta
     2461 tcagacaata catcaaacaa atcatggaat ataaggtgga ttttgtggtt ggtgtcttgg
     2521 gagtctttct ggctcaaggc ttgaatctct tgtttctcaa tgtcatcttt caacatattc
     2581 cattcctaga aggttggacc tttcaagaga tagctttcat ttatggattt tccttgattc
     2641 ccaagggaat ggaccatctc ttttttgaca atctctgggc actagggcaa cgcctagtcc
     2701 gaaaaggaga gtttgacaag tatctgactc gtcccatcaa tcctctcttt cacatcctag
     2761 ttgaaacctt tcagattgat gccttgggtg aactcttagt cggtggtatt ttattgggaa
     2821 caacagtgac cagcattgtt tggactcttc caaaatttct gcttttccta gtttgtattc
     2881 cttttgcgac cttgatttat acttctctta aaatcgcaac agccagtatc gccttttgga
     2941 ctaagcagtc aggcgccatg atttacatct tctatatgtt caatgacttt gctaagtatc
     3001 cgatttctat ttacaattct cttcttcgtt ggttgattag ctttatcgtg cctttcgcct
     3061 ttacagccta ctatccagct agctatttct tacaggaaaa ggatgtgttc tttaacgtag
     3121 gaggtttgat gttgatttct ctggttttct ttgttatttc ccttaaactt tgggataagg
     3181 gcttagattc ctacgaaagt gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa
     3241 ggaacttatg atgtttgtaa ttgaagaagt caaggatgaa aatcaaaaaa ggcagttgtc
     3301 gctgagattt tgaaggattt gccagaatgg tttggaatcc cagaaagcac acaaacctat
     3361 atagaaggaa ccacgacact gcaagtttgg accgcctatc aggagagtga tttgactgga
     3421 tttgtaagct tatcctattc gagtgaagat tgtgcagaga ttgattgtct cggcgtaaaa
     3481 aagcttatca aggtagaaaa attgggagcc aattgcttgc tactttagag agtgaagctc
     3541 gtaaaaaagt tggttatctg caggtcaaaa cagtggcaga agcttctaat aaagattatg
     3601 atcgaacaaa tgacttttat cgaggtcttg gctttaaaaa gttagagatt tttcctcaac
     3661 tatggaatcc gcaaaatcct tgtcagattt tgattaaaaa gcttgaataa tattacttga
     3721 catctattct cagagtgcta tactgtaagt gtaatcgccg atttagctta gttggtagag
     3781 caaggcactc gtaaagccta ggttataggt agataaacga ctgaggattt gaaaaaatag
     3841 ataggtagaa gataaccgtt aagccttact cttagcggtt atttatattg tttaatagcg
     3901 ctaatatttt atcaattatg cctgttttcg tgtttctggt agttgttcaa gtttattgct
     3961 actatttttg atggtatgaa tgtgcttata atgtatcccg gttaacgaaa gttttggact
     4021 tatactcttc gaaaatctct tcaaaccacg tcaacgtcgc cttgccgtgc gtatggttac
     4081 tgacttcgtc agttctatcc acaacctcaa aacagtgttt tgagctgact tcgtcagttc
     4141 tatctacaac ctcaaaacag tgttttgagc aacctgcggc tagtttccta gtttactctt
     4201 tgattttcat tgagtactaa tcttattttt taacgtgtgc taaaaaataa attaatgcat
     4261 gttaattttt cttgaattaa atttttttaa atgatatact gtttttatgg agagataaca
     4321 attatatata aatgtactac tctatttcct agataatact tagtaaaact ttttataaca
     4381 aaggctagca aagttaaagt ttattatcta ttggagttta aataaatatg taaggaatta
     4441 aaatgaaaaa aagtacagta ttgtcattaa ccacagctgc agttatttta gcagcctatg
     4501 cccctcatga ggtagtctta gcagacacat ctaactctga agatgcttta agcatctctg
     4561 ataaagaaaa agtagcagaa aataaagaga aacatgaaaa tatccatagt gctatagaaa
     4621 cttcacagga ttttaaagag aagaaaacag cagtcattga gggaaaagaa gttgttagta
     4681 aaaatcctgt gacagacaat aacactagca atgaagaagc aagaatcaaa gaagattcca
     4741 atcaatccca aggagatcat acggactcat ttgtgaataa aaacacagaa aatcccaaaa
     4801 aagaagataa agttgtctat attgctgaat ttaaagataa agaatctgga gaaaaagcaa
     4861 tcaagcaact atccaatctt aagaatacaa aagttttata tacttatgat agaattttta
     4921 acggtagtgc catagaaaca actccagata acttggacaa aattaaacaa atagaaggta
     4981 ttacatcggt tgaaagggca caaaaagtcc aacccatgat gaatcatgcc agaaaggaaa
     5041 ttggagttga ggaagctatt gattacctaa agtctatcaa tgctccgttt gggaaaaatt
     5101 ttgatggtag aggtatggtc atttcaaata tcgatactgg aacagattat agacataagg
     5161 ctatgagaat cgatgatgat gccaaagcct caatgagatt taaaaaagaa gacttaaaag
     5221 gaactgataa aaattattgg ttgagtgata aaatccctca tgcgttcaat tattataatg
     5281 gtggcaaaat cactgtagaa aaatatgatg atggaaggga ttattttgac ccacatggga
     5341 tgcatattgc agggattctt gctggaaatg atactgaaca agatatcaaa aactttaacg
     5401 gcatagatgg aattgcacct aatgcacaaa ttttctctta caaaatgtat tctgacgcag
     5461 gatctgggtt tgcgggtgat gaaacaatgt ttcatgctat tgaagattct atcaaacaca
     5521 acgttgatgt tgtttcggta tcatctggtt ttacaggaac aggtcttgta ggtgagaaat
     5581 attggcaagc tattcgggca ttaagaaaag caggcattcc aatggttgtc gctacgggta
     5641 actatgcgac ttctgcttca agttcttcat gggatttagt agcaaataat catctgaaaa
     5701 tgaccgacac tggaaatgta acacgaactg cagcacatga ggatgcgata gcggtcgctt
     5761 ctgctaaaaa tcaaacagtt gagtttgata aagttaacat aggtggagaa agttttaaat
     5821 acagaaatat aggggccttt ttcgataaga ataaaatcac aacaaatgaa gatggaacaa
     5881 aagctcctag taaattaaaa tttgtatata taggcaaggg gcaagaccaa gatttgatag
     5941 gtttggatct taggggcaaa attgcagtaa tggatagaat ttatacaaag gatttaaaaa
     6001 atgcttttaa aaaagctatg gataagggtg cacgcgccat tatggttgta aatactgtaa
     6061 attactacaa tagagataat tggacagagc ttccagctat gggatatgaa gcggatgaag
     6121 gtactaaaag tcaagtgttt tcaatttcag gagatgatgg tgtaaagcta tggaacatga
     6181 ttaatcctaa taaaaaaact gaagtcaaaa gaaataataa agaagatttt aaagataaat
     6241 tggagcaata ctatccaatt gatatggaaa gttttaattc caacaaaccg aatgtaggtg
     6301 acgaaaaaga gattgacttt aagtttgcac ctgacacaga caaagaactc tataaagaag
     6361 atatcatcgt tccagcagga tctacatctt gggggccaag aatagattta cttttaaaac
     6421 ccgatgtttc agcacctggt aaaaatatta aatccacgct taatgttatt aatggcaaat
     6481 caacttatgg ctatatgtca ggaactagta tggcgactcc aatcgtggca gcttctactg
     6541 ttttgattag accgaaatta aaggaaatgc ttgaaagacc tgtattgaaa aatcttaagg
     6601 gagatgacaa aatagatctt acaagtctta caaaaattgc cctacaaaat actgcgcgac
     6661 ctatgatgga tgcaacttct tggaaagaaa aaagtcaata ctttgcatca cctagacaac
     6721 agggagcagg cctaattaat gtggccaatg ctttgagaaa tgaagttgta gcaactttca
     6781 aaaacacgga ttctaaaggt ttggtaaact catatggttc catttctctt aaagaaataa
     6841 aaggtgataa aaaatacttt acaatcaagc ttcacaatac atcaaacaga cctttgactt
     6901 ttaaagtttc agcatcagcg ataactacag attctctaac tgacagatta aaacttgatg
     6961 aaacatataa agatgaaaaa tctccagatg gtaagcaaat tgttccagaa attcacccag
     7021 aaaaagtcaa aggagcaaat atcacatttg agcatgatac tttcactata ggcgcaaatt
     7081 ctagctttga tttgaatgcg gttataaatg ttggagaggc caaaaacaaa aataaatttg
     7141 tagaatcatt tattcatttt gagtcagtgg aagaaatgga agctctaaac tccaacggga
     7201 agaaaataaa cttccaacct tctttgtcga tgcctctaat gggatttgct gggaattgga
     7261 accacgaacc aatccttgat aaatgggctt gggaagaagg gtcaagatca aaaacactgg
     7321 gaggttatga tgatgatggt aaaccgaaaa ttccaggaac cttaaataag ggaattggtg
     7381 gagaacatgg tatagataaa tttaatccag caggagttat acaaaataga aaagataaaa
     7441 atacaacatc cctggatcaa aatccagaat tatttgcttt caataaccaa gggatcaacg
     7501 ctccatcatc aagtggttct aagattgcta acatttatcc tttagattca aatggaaatc
     7561 ctcaagatgc tcaacttgaa agaggattaa caccttctcc acttgtatta agaagtgcag
     7621 aagaaggatt gatttcaata gtaaatacaa ataaagaggg agaaaatcaa agagacttaa
     7681 aagtcatttc gagagaacac tttattagag gaattttaaa ttctaaaagc aatgatgcaa
     7741 agggaatcaa atcatctaaa ctaaaagttt ggggtgactt gaagtgggat ggactcatct
     7801 ataatcctag aggtagagaa gaaaatgcac cagaaagtaa ggataatcaa gatcctgcta
     7861 ctaagataag aggtcaattt gaaccgattg cggaaggtca atatttctat aaatttaaat
     7921 atagattaac taaagattac ccatggcagg tttcctatat tcctgtaaaa attgataaca
     7981 ccgcccctaa gattgtttcg gttgattttt caaatcctga aaaaattaag ttgattacaa
     8041 aggatactta tcataaggta aaagatcagt ataagaatga aacgctattt gcgagagatc
     8101 aaaaagaaca tcctgaaaaa tttgacgaga ttgcgaacga agtttggtat gctggcgccg
     8161 ctcttgttaa tgaagatgga gaggttgaaa aaaatcttga agtaacttac gcaggtgagg
     8221 gtcaaggaag aaatagaaaa cttgacaaag acggaaatac catttatgaa attaaaggtg
     8281 caggagattt aagaggaaaa atcattgaag tcattgcatt agatgcttct agcaatttca
     8341 caaagattca tagaattaaa tttgctgatc aggctgatga aaaggggatg atttcttatt
     8401 acctagtaga tcctgacaaa gatgcttcta aatatgaaaa acttggtgaa atttctgaag
     8461 ataaactcaa aaatgcaaag agcccagagg aaaataccaa taataatcaa gctaaggatg
     8521 aagattcaaa accagatgaa aaaagttcag ttgagggaga agctagcctt gaaataaata
     8581 aaactatttc aacaattaga gactttgaaa ataaagacct aaagaaactc attaaaaaga
     8641 aatttagaga agttgatgat tttacaagtg aaactggtaa gagaatagag gaatacgatt
     8701 ataaatacga tgataaggga aatattattg cttatgacga tggtagtgcc ttacaatatg
     8761 aaactgaaaa atttgacgaa ataaaatcaa aaatttatgg tgttctaagc ccatctaaag
     8821 atggacactt tgaaattctt ggaaagataa gcaatgtttc taaaaatgcc aaggtatatt
     8881 atggaaatag ctataaatcg atagaaatca aagcgactaa gtatgattca cattcaaaaa
     8941 cgatgatatt tgatttatac gctaatatta atgatattgt agatggatta gcttttgctg
     9001 gagatatgag attatttgtt aaagatgaca atcaaataaa agctgaaact aaaattagaa
     9061 tgcctgaaaa aaataaggaa actaaagcag aatatcccta tgtatcaagt tatgggaatg
     9121 taatcgaatt aggagaagga gatctttcaa agaacaaacc agacaattta actaaaatgg
     9181 aatctggtaa aatctattct gattcagaaa aacaacaata tctgttaaag gataacatca
     9241 ttctaagaaa aggctatgca ctaaaagtga ctacctataa tcctggaaaa acggatatgt
     9301 tagaaggaaa tggagtctat agcaaggaag atatagcaaa aatacaaaag gccaatccta
     9361 atctaagagt cctttcagaa acaacaattt atgctgatag tagaaatgtt gaagatggaa
     9421 gaagtaccca agctgtatta atgtcggctt tggacggctt taacattata aggtatcaag
     9481 tgtttacatt taaaatgaac gataaagggg aagctgtcga taaagacgga aatcttgtga
     9541 cagattcttc taaacttgta ttatttggta aggatgataa agaatacact ggagaggata
     9601 agtccaatgt agaagctata aaagaagatg gctccatgtt atttattgat accaaaccag
     9661 taaacctttc aatggataag aactacttta atccatctaa atctaataaa atttatgtac
     9721 gaaatccaga attttattta agaggtaaga tttctgataa gggtggtttt aactgggaat
     9781 tgagagttaa tgaatcggtt gtagataatt atttaatcta cggagattta cacattgata
     9841 acactagaga ttttaatatt aagctgaatg ttaaagacgg tgacatcatg gactggggaa
     9901 tgaaagacta taaagcaaac ggatttccag ataaggtaac agatatggat ggaaatgttt
     9961 atcttcaaac tggctatagc gatttgaatg ctaaagcagt tggagtccac tatcagtttt
    10021 tatatgataa tgttaaaccc gaagtaaaca ttgatcctaa gggaaatact agtatcgaat
    10081 atgctgatgg aaaatctgta gtctttaaca tcaatgataa aagaaataat ggattcgatg
    10141 gtgagattca agaacaacat atttatgtaa atggaaaaga atatacatca tttgatgata
    10201 ttaaacaaat aacagacaag acactaaaca ttaagattgt tgtaaaagat tttgcaagaa
    10261 atacaaccgt aaaagaattc attttaaata aagatacggg agaggtaagt gaattaaaac
    10321 ctcatagggt aactgtgacc attcaaaatg gaaaagaaat gagttcaacg atagtgtcgg
    10381 aagaagattt tattttacct gtttataagg gtgaattaga aaaaggatac caatttgatg
    10441 gttgggaaat ttctggtttc gaaggtaaaa aagacgctgg ctatgttatt aatctatcaa
    10501 aagatacctt tataaaacct gtattcaaga aaatagagga gaaaaaggag gaagaaaata
    10561 aacctacttt tgatgtatcg aaaaagaaag ataacccaca agtaaaccat agtcaattaa
    10621 atgaaagtca cagaaaagag gatttacaaa gagaagatca ttcacaaaaa tctgattcaa
    10681 ctaaggatgt tacagctaca gttcttgata aaaacaatat cagtagtaaa tcaactacta
    10741 acaatcctaa taagttgcca aaaactggaa cagcaagcgg agcccagaca ctattagctg
    10801 ccggaataat gtttatagta ggaatttttc ttggattgaa gaaaaaaaat caagattaag
    10861 acaaaagcta tagaaaaaaa tggtttatgt actgagatta gatagtgagg tgatgacata
    10921 gttttgtgaa aacggccatt tataactcaa ttatttagtt tacttcactt cactattgat
    10981 actatttgga gttattaatg gacttagttt agataactaa tgaattgatt gaaagggtta
    11041 gtattgacaa tattggtcat attgattaga aaatagagtc tatcaaaatt taaaggctaa
    11101 tagaggtgat gagacaattt caaggaatta agtagcgttt ggttgcttaa ttccttttta
    11161 tttggaagga agtttttcgt aaccgcccaa taacgaagtc tattggacgg ttacgatatg
    11221 atcactgact tcgtcagtct tatctacaac ctcaaaactg tgttttgagc aacctgcggc
    11281 tagcttccta gtttactctt tgattttcat tgagtattag aacag
//
LOCUS       DAVLGK010000058        11188 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLGK010000058 DAVLGK010000000
VERSION     DAVLGK010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.059"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(216..314)
                     /locus_tag="VXE01_001911"
                     /pseudo
     CDS             complement(216..314)
                     /locus_tag="VXE01_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(340..972)
                     /locus_tag="VXE01_001912"
     CDS             complement(340..972)
                     /locus_tag="VXE01_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0750768.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLVPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(994..1866)
                     /gene="sdaAA"
                     /locus_tag="VXE01_001913"
     CDS             complement(994..1866)
                     /gene="sdaAA"
                     /locus_tag="VXE01_001913"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV0750769.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(1875..2546)
                     /gene="sdaAB"
                     /locus_tag="VXE01_001914"
     CDS             complement(1875..2546)
                     /gene="sdaAB"
                     /locus_tag="VXE01_001914"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV0750770.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            2788..3375
                     /locus_tag="VXE01_001915"
     CDS             2788..3375
                     /locus_tag="VXE01_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0750771.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(3427..3747)
                     /locus_tag="VXE01_001916"
     CDS             complement(3427..3747)
                     /locus_tag="VXE01_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0750772.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            4173..4460
                     /locus_tag="VXE01_001917"
     CDS             4173..4460
                     /locus_tag="VXE01_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0750773.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            4512..6620
                     /locus_tag="VXE01_001918"
     CDS             4512..6620
                     /locus_tag="VXE01_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0750774.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTIPSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLSDVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSLFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSLPLLVLIFFAHALLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            6617..7258
                     /locus_tag="VXE01_001919"
     CDS             6617..7258
                     /locus_tag="VXE01_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750775.1"
                     /translation="MIELDNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSTKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSATLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            7476..8273
                     /locus_tag="VXE01_001920"
     CDS             7476..8273
                     /locus_tag="VXE01_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0750776.1"
                     /translation="MKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVALNPD
                     FAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKADLAI
                     SGVSKTDERSKVFDFSIPYYTAKNKLIVKESDLTTYQSVNDLAQKKVGAQKGSIQETM
                     AKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNFEKE
                     QDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            8239..8709
                     /locus_tag="VXE01_001921"
     CDS             8239..8709
                     /locus_tag="VXE01_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV0750777.1"
                     /translation="MRMPLKRPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVAVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQIEYQIAVAKKANEAKK"
     gene            complement(8999..9862)
                     /locus_tag="VXE01_001922"
     CDS             complement(8999..9862)
                     /locus_tag="VXE01_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0750778.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGARELSDHTEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKK
                     EVETHYQPKKL"
     gene            10328..10666
                     /locus_tag="VXE01_001923"
     CDS             10328..10666
                     /locus_tag="VXE01_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV0750779.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            10644..11015
                     /locus_tag="VXE01_001924"
     CDS             10644..11015
                     /locus_tag="VXE01_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEV0750780.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
BASE COUNT         3399 a         1920 c         2416 g         3453 t
ORIGIN      
        1 aacgcatatt atcaagttaa ataaccttgg taatatgcgt tttattatgt agagacttat
       61 actcttcgaa aatctcttca aatcacgtca acgtcgcctt gccgtatatg gttactgact
      121 tcgtcagttc tatccacaac ctcaaaacag tgttttgagc tgacttcgtc agttctatcc
      181 acaacctcaa aacagtgttt tgagctgact tcgtcagttc catccacaac cttaaaacag
      241 tgttttgagc agcccgcagc tagtttccta gtttgctctt tgattttcat tgagtattac
      301 ttcattttct tctgaaatgg aattgttacc cagtctatgc tattgaaaat acgccaaaac
      361 ctctaagggt ttgtgagcga tataatcagg ttgatagttt agtagatctg cttgctctcc
      421 aaatccccaa gtgatggcca atttctgaat acctgtttct cgagctccca gcatatcaaa
      481 cttggtatct ccgatgatga tggcttgttc tggtactagt tgatgtgtct gcaaggcttg
      541 gtgaatgaca tctgccttat ggggtgcttc agggctagaa ccataaatgc catcaaagaa
      601 atgatggatt tccaagtttt ttgccatgtc ttgagcagta gatgtattct ttgtcgtggt
      661 gatgtagagt ggataactgc tcgataactc ctcaagcaag tctataatct gaggaaagag
      721 ttgagcttca tagatgcctt ttgccttata gtaagaacga tatatctgca cggcttcaga
      781 aatttggtct ttggacaggc aggtcgcaaa actactttcg agaggtggtc ccataaaacc
      841 acgaatagtt ttggcatcag ggctaggcac ccccagctct ttaaaggtat aggtaaaggc
      901 attgtgaatc ccgatagaac tatcaacgag ggttccatcc aaatcgaaaa aaatcgctgt
      961 gatagaggtc atggtttctc ctatttgata agcttattct ccgaaaattt ctttttggag
     1021 gcgacgacca gtaggggtgg tagcgagtcc accttcagct gtttcacgaa aggcagttgg
     1081 catgcttgct cctacttggt acatggcatc gatcacttca tccacaggga ttttagattc
     1141 gatacctgcc aaggccatgt ctgctgcgat gaaagcaaag ctagctccca tggcattacg
     1201 tttgacacag ggaacttcga ccaaacctgc aacagggtca cagatgaggc ctagcatatt
     1261 tttaatgaca aaggcaatag cttgactggc ctgataaggt gttccacctg cagccagagt
     1321 caaggcggca gcactcatag cagaggctga accaacttca gcttgacacc caccctcagc
     1381 acctgagatg gaggcattgt ttgcgatgac tagtccaaag gcaccagcag caaagaggaa
     1441 atccaattgt tgctcgtggc tgaggtctaa tttttcaata gcagcagtga gaacggaagg
     1501 gagacaaccg gcacttcctg cggtaggagt agcgcagacc aagcccattt tagcattgtg
     1561 ttcattgact gcgatagcat ttcgggcagc agagagaatc gtataatctg acagagtttt
     1621 tccgttttcg atgtagtgat ccaatttggc agcatctcca cctgtcaggc cactacgaga
     1681 tttattttca ttgaggccaa gttggacaga ggctttcata acttccagat tgcgttccat
     1741 gagaaggaag acttcttcac gttcgcgacc ggtcaattca aactctgttg taatcatgag
     1801 ttctgcgaca tttccttgaa agtccagatc tgcttgctcg accaattctt tgatagaata
     1861 aaacatgctt cctcctattt aaagaaattg acattgtgga gatgagggat ttttcgaatt
     1921 tcttcgatag cctcatcaca gttgcgactg tcaacttcga taatcataat ggctttttca
     1981 ccagcttttt cacgagtgac attcatctgg gcgatattga taccatagcg ggaaagcgcc
     2041 tctgtaacaa gggcaatcat acctggaata tcttgatgaa cgatgatgat agtcggtgta
     2101 ttcatattga gagagacggc aaaaccattg agttcggtta cctgaatatt tcctccaccg
     2161 atagaaatac cagtcacgct gatggtcttg tgggcatttt taacagtaat tttagtggtg
     2221 ttagggtgag gggcattgct gtctttctga atggtccaga caatcttgat accacgcttg
     2281 tgggcaattt ccagactatt tggaatttca ggatcatctg tatccattcc caaaatacct
     2341 gcaacaaggg ctaggtctgt tccgtgacca cgataggtct tggcaaatga gttaaaaagt
     2401 tggaattcaa cttctgtcgg agtatcatca aaaatggaag agacaatctt cccaatacga
     2461 acagcaccag cggtatggct actagatggg ccaatcataa ctggtccgat gatatcaaag
     2521 acagattgaa aacgaagtga tttcatcagt ttccccttat aaaaattctt atctctatta
     2581 tatcaaagaa tgaggggctt ggctttaatt gtggatgaaa acctttctaa tacctcaaat
     2641 agcataaaaa tagtatcttt tatgacaaaa aacaccttat ttagggaaat aaaaaataat
     2701 tttgtaatat ttctacataa aagtgtcaag aaacggtaat atttaaaggg tatgatagaa
     2761 ctatagaaag aaggagaatt ttcgaatatg aaatcaataa ctaaaaagat taaagcaact
     2821 cttgcaggag tagctgcctt gtttgcagta tttgctccat catttgtatc tgctcaagaa
     2881 tcatcaactt acactgttaa agaaggtgat acactttcag aaatcgctga aactcacaac
     2941 acaacagttg aaaaattggc agaaaacaac cacattgata acattcattt gatttatgtt
     3001 ggtcaagagt tggttatcga tggccctgta gcgcctgttg caacaccagc gccagctact
     3061 tatgcggcac cagccgctca agatgaaact gtttcagctc cagtggcaga aactccagta
     3121 gtaagtgaaa cagttgtttc aactgtaagc ggatctgaag cagaagccaa agaatggatc
     3181 gctcaaaaag aatcaggtgg tagctataca gctacaaatg gacgttatat cggacgttac
     3241 caattaacag attcatacct gaacggtgac tactcagctg aaaaccaaga acgtgtagca
     3301 gatgcctacg ttgcaggacg ttacggttca tggacagctg ctaaaaactt ctggcttaac
     3361 aatggctggt attaagaact aacgaacaaa taatatgtaa agagtcgagg aaatccctcg
     3421 gcttttttat ctttccttcg cttggtaata gatctctact tcttttttga gatgagacag
     3481 catagaagtt tcctcggtta gctctaggag tgagaaacct ttttggataa gtttcgcatc
     3541 atccctacaa atcccaatag ggacatagca gatagccagc ctatcgtagc ttttcttatt
     3601 cttggcgtcc tccagtaaag tgtagcagat ttgcttacac atgtttttat cttgattgta
     3661 tagatagagt gtggaaaggt tgagcaggat tgctattcgc aagtcatata aatgttgata
     3721 gtttttatag acttctaagc gttgcaagat tttctcggat tattgacaaa taaacggaca
     3781 ttctgataga cgattgccct agcggcttag tgtaaacttt acaaatttgg cttgtaattt
     3841 tttttataaa attcacttca gttacttgac agttattata ttttcactta ttatatagat
     3901 aaaaggatgg gataggagtt taaaaatttg aaagcgctat ccatattgtt tattggactg
     3961 attcttgagt aatagttaga gtgtgcttaa tactactctg gttgttcaag gacctgatac
     4021 agaagcgcac cattctcccg gttaagagta agttcgttgt taaaaaatga aatgagatag
     4081 aaggaaggtg agtccaatgg actacgatac ttgttgataa attactatag ctgtttttac
     4141 ggaacagctc tcgataatag gagaaataaa tcatgagaaa attagttaaa attggtgttg
     4201 catctttaat ggtatgtggt atacttgcta ctacaaatgc tttagcagta tgggttgagg
     4261 gtggtcaatg gaactatgga gtaggttgga caggaacttt tggatattct gattacttac
     4321 attctactcg atatcataca gcaactgtta gacatggggg tagaacctct aaggattatg
     4381 caaaacctga ggcatgggct agagcttccc tcaccaagat tccgccaaca ggaatggaat
     4441 atttctatgg atttgagtaa aattcttccc tctcctattt ggagagggaa aactgtagtg
     4501 gaggcacttt tatgaaaaaa atcagtaatt tctgtatgtt actcctgctt ctgtgtacca
     4561 ctttttttgt ttttaatgta aactatacac gagaagtggt tcggattcaa gaaatgggaa
     4621 agactgtaga ttctttggat ttgtatttga aagatattaa cgaacctgca gcgtctgttc
     4681 ttcgattttt tgaggatgta tcaaaggagt ataaagtctc catcatcaaa acagacagtg
     4741 gtgatgaggt ggtcaagtct ggtgtttttg ataaagatac cttcccctac caagagtttg
     4801 ggatttcttc tcttgatttt accacagatg gtgaaggagt ctatagtaat aaagaaattt
     4861 ccaataaact tggtacgatt ccgacctttc taaaagccaa acctattcag cttatgactt
     4921 ttcaaaccta tatcaaggat acatctcgta gtttaaatgg tcgctatacg ataccttcta
     4981 cacaagagat ggacaaggat aggattgtac agaaatggag cgattttttc aagatagacc
     5041 aggctacctt gctagagccg acctacaaaa gtgcagtgga agtcataaat cgagatttgc
     5101 ttttatctgc cattgttttt gtcttggcta ttttgcttct tgtgttagtg acagtgtatc
     5161 aaccgatgat ggagatgaaa cgagttgggg tacaaaaatt acttggtttt caagataggg
     5221 ctgttttatc tgatgttgta aaaggcaacc tttacctcct cctaggtggg gctcttgtga
     5281 tcaatctagg cgtgtttttc ttgcttgatt ataagccaaa agatttgttt cctatgctgt
     5341 ggttgtctct ttttttgctg ttgcagcttt atctctttat cagttggttg acttacctct
     5401 taatccaaaa aatgacaatc agctctctgc tgaaaggttt ttcatctttc aaatttggtc
     5461 tactctttaa ttatttgatg aaaattggaa ctaccatttt actgacagtc ttgctagttg
     5521 gggtaggaaa aagtttggag caagaaaaca aagagttgga ttaccagaaa cagtggatca
     5581 gccaaggaaa ttatctgacc ttagaaactt tccaactcaa tgacaacttg tggcaagagc
     5641 agttggcagg ctcagggaag gcattggatt atttctatcg attttatcag gatttggtag
     5701 aaaaaacgca ggcgggctat gtgcagagta gcagtcttcc tgtaaaaaat tttgtccaat
     5761 cagaacagat tcagcaatat cagttaacag atacggtgga tgtttactat gccaatcgca
     5821 attttctaaa gagcaaggga ttcaagctac cagataccgg tattaaaaaa gttattttga
     5881 tgccagcaag tacgaaaggt gaagaagata aaaatcagct cttggggaag ttaattgcct
     5941 ttcattcgat gaagtatgaa gagcagcaaa aacgaacgat agaggagatg gatgtcgaga
     6001 ttgcctatta tgaaggagat tggtcatttt tcccatatag tgataagcga aaggaaaatc
     6061 tctccaatcc aattattagc ttggtcaatg attctgatat gatgtgggat gagaaagcct
     6121 ccctgtcaac aactggctta aataatccga ttaaaattga aaatacggtt caacatcaaa
     6181 aagagattac agagttagtt gagaaattgt cagatggaaa ttatttaaaa ttttcatcta
     6241 ttcaagccat tcaacaagag aaagtggatt cttatcgaga tgctgttcgg aattttaacc
     6301 tactctttgc tttgtttggt ctccttagca tgatgatttc ctacttctta ctagtaataa
     6361 ctttcttatt gaagcgcagg gatattatta ccaagaagtt tatggggtgg aaactggtcg
     6421 atcgctaccg ccctctcctc gttctgctct tgctgggcta tagtctgcct cttctagtct
     6481 tgattttctt tgcccatgcg ctcttgccac tcctactttt tgcaggtttt acatgtttgg
     6541 atatactatt tgtgctaggc ttggcttcta ggatggagaa aagaagtcta gtagagttat
     6601 tgaaaggggg catcttatga ttgagttgga caatattacc aaaaccattg gaggaaaagt
     6661 gattttggat aacttatctc tcaggattga tcagggggat ttggtagcca ttgttggcaa
     6721 gagtggtagt ggtaagtcaa ccttgttaaa tttattaggt ttgatagatg gtgattacag
     6781 cggacggtat gagatttttg gtcagacaaa tctagcggtc aattctacca agtcgcaaac
     6841 aataatccgt gaacatatct cttatctatt tcaaaatttt gccctgattg atgatgaaac
     6901 ggtcgagtac aatcttatgc tggcgctgaa atatgtgaaa ttgtccaaga aagacaagct
     6961 caaaaaggtg gaagagattt tagagagagt aggtttgtca gctactttgc accaaaaggt
     7021 ctccgagttg tctggtggcg aacaacaacg aattgcagtt gctagagcca tcttaaaacc
     7081 cagccagctg attttagccg atgaaccgac aggttctctg gatcctgaaa atagagattt
     7141 ggtcttgaag tttctcttag agatgaatcg agaggggaaa acagtcatta tcgtgaccca
     7201 cgatgcttat gtagcccaac aatgtcatcg aatcattgaa ttaggcgagg gaaaatgagt
     7261 tcgttcagct tcatttgacc gactgaatac tcatattttt cagagagaaa tagcataaat
     7321 aggcctagga atgatatttt tatgtcattt tcctgggttt ttctgtttta aattgaaaaa
     7381 aaattacaat ttaggcttga caaagtatgc atatagatgt attgtttata caaacaaaag
     7441 gaataaacat aaagtaggct ttattatgaa taaagatgaa gaaggtgttg atgacgatgt
     7501 ttggtttagt gatgctcccc ctactatttg cttgtagcaa caatcaatcg gctggaattg
     7561 aagccatcaa gtccaaagga aaattggttg tagccctcaa tccggatttt gctccatttg
     7621 aataccaaaa agtggttgat gggaaaaatc agattgtggg ttcagatatc gaattagcca
     7681 aggctatcgc aacagaacta ggtgtcgaat tggaactatc tcccatgagt tttgataatg
     7741 tactggctag tgttcaatca ggaaaagccg accttgccat atcaggtgtt tctaagacag
     7801 atgaacggag caaggtgttt gacttttcca ttccctacta tactgcaaaa aataaactca
     7861 ttgtcaaaga atctgacttg actacttatc agtctgtaaa cgacttggcg cagaaaaagg
     7921 ttggcgcgca gaaaggttcg attcaagaga cgatggcgaa agatttgcta caaaattctt
     7981 ccctcgtatc tctgcctaaa aatgggaatt taatcacaga tttaaaatca ggacaagtgg
     8041 atgccgttat ctttgaagaa cctgtttcca agggatttgt ggaaaataat cctgatttag
     8101 caatcgcaga cctcaatttt gaaaaagagc aagatgattc ctacgcggta gccatgaaaa
     8161 aagatagcaa ggaattgaaa gaggcagtcg ataaaactat tcaaaagttg aaggagtctg
     8221 gggaattaga caaactcatt gaggatgcct ttaaagcgtc cattgaaaaa tagaaagaag
     8281 gaaaagaaca tgagtaaaga aaaagtaatt ttggcctatt ctggcggttt ggacacatca
     8341 gttgctatta cctggctgaa gaaagattat gatgttgttg cagtttgtat ggatgtgggt
     8401 gaagggaaag acttagattt catccatgat aaggctctca aggttggggc agtcgaatct
     8461 tatgtcattg atgttaagga cgaatttgct acagattatg tgctagtggc tcttcagtca
     8521 catgcctact atgaacaaaa gtaccccttg gtatctgcct tgagccgccc tcttatttct
     8581 aaaaaattgg ttgaaatagc gcatcagaca ggagcgacta caattgctca tggttgtaca
     8641 ggtaagggga atgaccaaat cgaataccag attgcagtcg ctaagaaagc gaatgaagct
     8701 aaaaagtgat ggagtgatgg gttcagaata agaggttggt cgattggcag cctctttctt
     8761 gtcgttgaaa aagtgagata tattgacttt tgaaaaaaat gtcataattg agttgggata
     8821 aacgtaaaag tcatactttc tcgttaaatc gttcggcgat tcatggtgac atggacacat
     8881 agtagtaagc acactatgtg gcttagcaga gctaaaaact tctggtttaa caatggctgg
     8941 tattaagaac taacgaacaa ataatatgta aagagtcgag gaaatccctc gacttttttt
     9001 ataatttctt tggttgataa tgggtctcta cttctttttt gagatgagac agcatagaag
     9061 tttcctcggt cagctctagg agtgagaaac ctttttggat aagtttagca ttatctgtac
     9121 aaatcccaat acggacatag cagatagcca gcctatcgta gcttttctta ttcttggcgt
     9181 cctctagtaa agtgtagcag atttgcttac acatgttttt atcttgattg tatagataga
     9241 gtgtggaaag gttgagcagg attgctattc gcaagtcata taaatgttga tagtttttat
     9301 agacttctag gcgttgcaat atttttccag tgatgagatg gaggtattca atgggaaaac
     9361 tgaaaagaat ggtattgagg atttttagat cactctcata ccatgtatct tgtttttcaa
     9421 tttttctcca aagttttttg acaacctgtt ctgtgtgatc tgatagttcc cttgccccgt
     9481 gttgacggat ataaatgaca acttcaagca tatctctgat ttcttctata gggagatcgt
     9541 ggtgggtctt gaggtagtct tggcattttt gaaataaatt gacaagatcg ctggtcccga
     9601 taatggaacg catattgaga taggtttgca taatctctgt gcgttgactt ggttgataaa
     9661 gttgacagat atattcaaac tcttcaaaac tcatattgat ttgacggaga agaaattcca
     9721 tattttcata ttttggggtt gtcttgccac tttcgatttt tgataagctg gttcttgaga
     9781 gaacaccccc acagacctct tcttgggtca gcccctttga ctcacgtatt tctttataga
     9841 cctttccgaa atcataacgc atgattttct ccttttcgtg aaaaaagtta acaaacaata
     9901 aaattttgtt aaaaatattg tatcatagca atgtaaaaag taaaaaagaa agtcgaaata
     9961 aatttgtgaa aaaagttaac gtaattttaa aatgagctta ataagaggta ctatgtaggt
    10021 agaaaataaa gataggagaa aaagtatgaa taaaaaaata ttttgtattc tagtatgtat
    10081 tatattattg attagtctgg ctataatctt tccatggggc tggccgatat aatgtaaggg
    10141 agtttgagtt gttaaaggag gctcagtcct tgggcaaaaa tctgctgtac tacaatgctt
    10201 ggaaagatat caagaacaaa gaatgatacg gttgaaaata aattaattca agaactactg
    10261 ggcagtgatt gaggtttggg tgacatcaaa gaaaagttag attaattcta aagaattgag
    10321 tatttctatg ttaaaaaaat atccttgtac gatgcaacat gaccagtcag attgtgctgc
    10381 ggcagttgtt tcaacagttc ttttatctta caaaaaggaa ctatcaatca tgaagattcg
    10441 ggaaattatt ggtacagaca tgtatggaac gactgtcagt ggtattgttt caggtctgaa
    10501 taagttgaat tttacagtaa aagctgttcg agtagcactg gaagatttga ctccaaaatt
    10561 aacatttcct gcgattcttc aagttaagaa tgatttaggt caaaatcatt ttgtggtatt
    10621 acatagtata aaggagaaaa taaatggaac tcgtattacc aaataattat gttgtgattg
    10681 atgaagaaga gatgatgtac cttgatgggg gggctatata tatacccagg tgggcaatta
    10741 caggagccat tactggtgca gcatatgcag cattagcagc agcaggaggt ggaggccttc
    10801 aactagttct tgcatcttat ggattacgct ccgcactggt agctgggatt gttaaaggtt
    10861 taggagtatt aggaattcat attggaaatg cttttgcaaa tactgttatt agaagtattg
    10921 catctgctgg aattggtgct ggagctgatt ggatttttac caatattatt gatggctggg
    10981 atgggcgacg tgataatcaa ttgagaatag gataatagta ttatgatggt tgttttaatt
    11041 tcagttattg ttgcattcct gtaccataaa attacagagt atgtcaacaa caggaaaatt
    11101 gatattgtta tttttctatc attgctgatt tctcatttta tttggaatta ctatttttta
    11161 ccaattgaaa tattgatagc aatcagtg
//
LOCUS       DAVLGK010000059        11161 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLGK010000059 DAVLGK010000000
VERSION     DAVLGK010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11161
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.060"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            113..493
                     /locus_tag="VXE01_001925"
     CDS             113..493
                     /locus_tag="VXE01_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750781.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGVAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            687..977
                     /locus_tag="VXE01_001926"
     CDS             687..977
                     /locus_tag="VXE01_001926"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750782.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            1028..1720
                     /locus_tag="VXE01_001927"
     CDS             1028..1720
                     /locus_tag="VXE01_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV0750783.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1773..3206
                     /locus_tag="VXE01_001928"
     CDS             1773..3206
                     /locus_tag="VXE01_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0750784.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMM"
     gene            3270..4184
                     /locus_tag="VXE01_001929"
     CDS             3270..4184
                     /locus_tag="VXE01_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-fucosidase"
                     /protein_id="HEV0750785.1"
                     /translation="MLRETVRFWNAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQS
                     LIWQLFHDFIQAAQELGLDEDLLTEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNE
                     KVEAQHRHASHLVGLYPGNLFSYKGQEYIEAARASLNDRGDGGTGWSKANKINLWARL
                     GDGNRAHKLLAEQLKTSTLPNLWCSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAA
                     LPDAWSTGSVSGLMARGHFEVSMSWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMN
                     QEKIKAKCMGKDCISVATAEGDLVQFYF"
     gene            4434..5135
                     /locus_tag="VXE01_001930"
     CDS             4434..5135
                     /locus_tag="VXE01_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750786.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5137..7845
                     /locus_tag="VXE01_001931"
     CDS             5137..7845
                     /locus_tag="VXE01_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0750787.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVATVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7941..8432)
                     /gene="tpx"
                     /locus_tag="VXE01_001932"
     CDS             complement(7941..8432)
                     /gene="tpx"
                     /locus_tag="VXE01_001932"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV0750788.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8555..9484)
                     /gene="psaA"
                     /locus_tag="VXE01_001933"
     CDS             complement(8555..9484)
                     /gene="psaA"
                     /locus_tag="VXE01_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV0750789.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9516..10364)
                     /locus_tag="VXE01_001934"
     CDS             complement(9516..10364)
                     /locus_tag="VXE01_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0750790.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10361..11083)
                     /locus_tag="VXE01_001935"
     CDS             complement(10361..11083)
                     /locus_tag="VXE01_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0750791.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3282 a         2064 c         2533 g         3282 t
ORIGIN      
        1 atattttatt tcatattata caaattttta ttttataata tcagaaaata ctttttttaa
       61 aagcaaatat gatacaattt tatttgaaaa aaataaaaaa ggagatttta ttatgaaatt
      121 aaaaacactt gctttaatta gtggtatcgt cggtcttgtg ggaggaattt tacttcttat
      181 tggtcctttt gtcttgttgg gaacagcggt aaacacagtt gctacaactc ttaatggagg
      241 agctactgca ggggcttttt caggtgttgc cttactcttg aatgccttga agattgcaaa
      301 tcttgttctt ggtatcattg ctattgttta ctataaagga gataatcgtg taggtgtagc
      361 tccgtctgta ctaatgattg tttttggtgg agttagtctc attccattct taggatgggt
      421 tggggggatt cttgttatta tcggaggatc tctattcctt gcaacattga agaaattcaa
      481 atcagaagaa taaaaggtat tttagcatga aaagaacaaa aaagtttatc ggtataggag
      541 tagctctatt atctcttttt cttctagttg catgtggaac ataaagttca aaggatactt
      601 caacaagtaa tgatgagaag acagtagcaa catccaatag ttcaaaagaa acaatcactt
      661 tcgatacacc ggttgtaaca gacgatgtga ttgaatcaat acgcacttat gcagattata
      721 tagatcttta taaaaatatt tttgatgatt attttactaa agctgaggaa ggtttcaaag
      781 gcacagctat ggaaaataat gactcgttta ctaaactaaa agagtcaact caaaaattat
      841 tcgatgcgca gaaaaaaagg ttaaataatg aagatagaat agaaacaact aaaaacaatg
      901 tgattgccaa acattgtcaa acagtccttt cctttttggt tttgactagc ttttttgtga
      961 aaaattgtgt aaaatagaat agataaacga ggggaaacct cggaaaattt aaaggagaat
     1021 ccatctaatg gtaaaattgg tttttgctcg ccacggtgag tctgaatgga acaaagctaa
     1081 ccttttcact ggttgggctg atgttgattt gtctgaaaaa ggtacacaac aagcgattga
     1141 cgctggtaaa ttgatcaaag aagctggtat caaatttgac caagcttaca cttcagtatt
     1201 gaaacgtgct atcaaaacaa ctaacttggc tcttgaagct tctgaccaat tgtgggttcc
     1261 agttgaaaaa tcatggcgct tgaacgaacg tcactacggt ggtttgactg gtaaaaataa
     1321 agctgaagct gctgaacaat ttggtgatga gcaagttcac atctggcgtc gttcatacga
     1381 tgtattgcct ccaaatatgg accgtgatga tgagcactca gctcacacag accgtcgtta
     1441 tgcttcactt gacgactcag taatcccaga tgctgaaaac ttgaaagtga ctttggaacg
     1501 tgctcttcca ttctgggaag ataaaatcgc tccagctctt aaagatggta aaaacgtatt
     1561 cgtaggagct cacggtaact caatccgtgc ccttgtaaaa cacatcaaag gtttgtcaga
     1621 tgacgagatc atggacgtgg aaatccctaa cttcccacca ttggtattcg aattcgacga
     1681 aaaattgaac gtcgtttctg aatactacct tggaaaataa aaaattgtaa gtctagaatt
     1741 gatttctagg ctttttatgt tagtatggaa gtatgataag gaataaaaaa caagattatg
     1801 tactggccta caagcaacca gtttcaacca cttacatggg ttgggaagaa gaagctttac
     1861 cgataggcaa tggttcttta ggagcaaaag tatttggcct tataggggct gaacggattc
     1921 aatttaatga aaaaagtctc tggtctggag gtccacttcc tgatagttca gattatcagg
     1981 gtggaaatct tcaggatcag tatgtttttt tagctgagat tcggcaggct ttggagaaga
     2041 gagattacaa tctggctaag gaactggctg agcagcacct aattgggcca aaaacgagtc
     2101 aatatgggac ctatctgtct tttggggata ttcacattga gttcagccag caaggtacga
     2161 ctttgtctca ggtgacggac tatcagagac agctgaatat tagtaaggca cttgtgacga
     2221 cttcttatgt ctataaggga acgcgatttg aacgtgaagc ttttgcgagt tttccagatg
     2281 atctcttggt tcagcgtttt actaaggaag gggcggaaac tctagatttt actatagaac
     2341 tatccttgac ctgtgatttg gcttctgatg gaaagtatga gcaggaaaaa tctgattaca
     2401 aggagtgtaa gttggatatt actgattctc atatcttgat gaagggaaga gttaaggata
     2461 atgatctgcg gtttgctagt tatctagctt gggaaacgga tggagatatt agagtttggt
     2521 cagatagggt tcagatatca ggagccagtt atgccaatct cttcttggcc gctaagacgg
     2581 attttgccca aaatcctgct agcaattatc gcaagaaact agatttagag caacaggtga
     2641 tagacttggt ggacacagct aaagaaaagg gctataccca attgaaatca aggcatatcg
     2701 aggactacca agccttattc cagcgtgttc aattggattt ggaagctaat gttgacgcat
     2761 tcactacaga tgatttgtta aaaaattata agccacaaga agggcaggct ttggaggagc
     2821 tgttcttcca gtatggacgg tatttattga ttagttcgtc cagagactgc ccagatgctc
     2881 taccagctaa cctacaggga gtctggaatg cggtcgacaa tcctccttgg aattcggact
     2941 atcacttaaa tgtcaatctg cagatgaatt attggccagc ctatgttacc aatctcctag
     3001 aggcggtctt tccggtcatc aactatgtag atgatttgcg tgtctatggt cgtctagcgg
     3061 ctgtaaagta tgcaggaatc gtctctcaaa aaggtgagga aaatggttgg ttggttcata
     3121 ctcaagcgac tccctttggt tggacggcac ctggttggga ttactattgg ggttggtcac
     3181 cagctgccaa tgcgtggatg atgtaaaccg tttatgaagc ctattcattt tatagggacc
     3241 aagactatct cagggagaaa atttatccca tgttgaggga aacggttcgt ttttggaatg
     3301 cctttttaca taaggatcag caggcgcagc gttgggtgtc ttctccgtct tattccccag
     3361 aacatgggcc gatttcgatt ggcaatactt atgaccaatc tctgatttgg cagttatttc
     3421 atgattttat tcaggctgct caggaattgg gactggatga ggacttgttg actgaggtta
     3481 aggagaagtc tgatttacta aatcctttgc aaatcactca atctggtcga atcagggagt
     3541 ggtatgagga ggaagagcag tattttcaaa atgagaaagt ggaggcccag catcggcacg
     3601 cttcccatct agtgggactc tatcctggca atctctttag ctacaaggga caagagtata
     3661 ttgaagcggc acgtgctagc ctcaatgatc gtggagatgg cggcacaggc tggtccaagg
     3721 ctaataagat caatctctgg gcgcgtttgg gagatggcaa tcgagcccat aaattattgg
     3781 cagagcagtt aaaaacatcc accttgccaa atctttggtg tagccatcct ccttttcaga
     3841 tagatggtaa ttttggtgct actagtggca tggcagaaat gttactccag tctcatgcag
     3901 cttatctggt acctctagct gccctacctg atgcttggtc aacaggttct gtttcaggct
     3961 taatggcacg tggacatttt gaagtgagca tgagctggga agataaaaaa ctcttacagt
     4021 tgaccatttt atcaaggagt ggaggagatt tgcgagtttc ttatccagat attgagaaga
     4081 gtgtgattaa aatgaatcaa gaaaaaataa aagcgaaatg catggggaaa gattgtattt
     4141 cggtggcaac agcagaaggt gatcttgttc aattttattt ttaagaagat gttataaggc
     4201 agtaatttga aacttccttt taataaggat ttaagaatat aggcagtttc caactagttg
     4261 aaaaagcgtt ataatgataa taggaagtaa tactcaatga aaatcaaaga gcacaaacta
     4321 ggaagctagc cgcaggttgc tcaaaacagt gttttgaggt tgtagatgga agctgacgtg
     4381 gtttgaagag agattttcga ggagtataat ttgtttgata gagggtgggt ctgatggctt
     4441 atattgagat gaaacactgt tacaagcgtt atcaggttgg ggacacggag attgtggcca
     4501 atcgtgatgt gaattttgag attgaaaagg gggagctggt tattatcctt ggtgcttcag
     4561 gtgcaggcaa gtcaacagtt cttaaccttc ttgggggaat ggataccaat gatgaagggg
     4621 aaatctggat tgatggtgtt aatattgcgg attatagttc ccaccagcgc accaattacc
     4681 gtagaaatga tgtggggttt gtttttcagt tttataatct agtttctaat ctgacagcta
     4741 aggaaaatgt ggaactggct tctgaaattg tgacagatgc cttgaatcct gatcaggtct
     4801 tgacagatgt aggtctggct catcgtctca ataactttcc agcccagctt tctggagggg
     4861 agcaacagcg agtctccatt gcacgcgcgg tagccaaaaa tcctaaaatt ctcctttgtg
     4921 atgaaccgac tggagccttg gattatcaga cgggcaagca ggttttgaaa attctccaag
     4981 acatgtctcg tcaaaaggga gcgacggtga tcatcgtgac tcataatgga gctttggcgc
     5041 ccattgctga tcgcgtgatt catatgcacg atgccagtgt caaggatgtg gtgctcaacc
     5101 agcatcctca ggatattgac agtttggagt actagcatga tcaagcgaaa aacttattgg
     5161 aaggacttaa ttcagtcctt cacagactcc aaggggcgtt ttttatccat cttgatcctg
     5221 atgatgttgg gatctctagc cttagtaggc ctcaaagtaa ccagtcccaa catggaggcg
     5281 acagctaatg cttatttaac aactgctcaa accttggatt tggcagtcat gtctaactat
     5341 ggcttggatc aagcagacca agaagaacta aaacagacgg agggcgcaga ggtcgagttt
     5401 ggctatttga cagatgtgac tatggataat gggcaggatg ccattcggct gtactccaaa
     5461 ccagagcgaa tttcaacctt tcagctaaga aagggacgac ttcctcagtc agacagggaa
     5521 atcgctttgg ccactcattt gcaaggccaa tacagcgtgg gacaggagat tagttttaaa
     5581 gaaaaagaag agggtcattc ctctttaaaa gaccatactt ataccattac tggttttgtg
     5641 gattcggctg aaatcctctc ccagcgagat atgggctacg caggaagtgg aagtgggact
     5701 ctgacagcct atggggtgat tttacctagt cagtttgatc agaaagtcta caatatagct
     5761 cgtttgaaat atcaagattt agcaggttta aatgcctttt catcagctta tgaagaaaaa
     5821 tccaagcaac atcaagaaga gcttgaacaa attttatcag ataatggcaa ggtacgtctg
     5881 caacttttga aaaaagaagg acaagagtct ctagacaagg ggcaagagac ccttgacaag
     5941 gctcagacta atttgcagga aggcaagcgt cgtttagcag ctgctcaagc tcgtatacag
     6001 gctcaagaaa gtcaactagc cttgtttcct caagttcaga gagagcaggc tagtgctcaa
     6061 cttacccaag ccaagcagga attgggcaag gaagaggaca aactaaagca agctgaacaa
     6121 aatctagccc aagaaaagga aaaattagaa aaacatcagc aagtcttgga cgatttggcg
     6181 gagccaaggt atcaggtcta taatcgtcag accatgccag gtggtcaggg ctatcttatg
     6241 tatagcaatg cttcatccag tattcgagca gtgggcaata tctttcctgt ggtactttat
     6301 gccgtagcag ccatggtgac ctttacgacc atgactcgct ttgtagacga agagcgaact
     6361 catgcaggga tttttaaggc cttgggttac cgtagtaagg atattatcgc caagtttctc
     6421 ctttatggac tagtagctgg gactgttgga acggctctag gtagtatact tggtcattat
     6481 ttgctagcca gtgtaatttc aagtgtcatt acaaaaggca tggtggtggg agaaacccag
     6541 attcagttct attggaccta tagcttacta gctcttgtct tgagctggtt ggcgagtgtg
     6601 ttaccagcct atctggtggc ttggagggaa cttcatgacg aagcagccca gcttctactt
     6661 cctaaacctc ctgtcaaagg agctaaaatc ttattggagc gtatcggttt tatctggcgt
     6721 cgtctcagtt ttactcataa ggtaacagcc cgcaacatct ttcgttataa gcagagaatg
     6781 ttgatgacaa tctttggtgt ggcaggttct gtagctctgc tctttgcagg tttgggaatc
     6841 caatcttctg tagcaggagt tccgtctaaa cagtttcaac aaatccaaca gtatcagatg
     6901 cttgtctctg aaaatcctag tgcgaccaat caggacaagg tagagctagc agaagtgttg
     6961 aaagggcagg agatactagc ctaccagaaa atctattcta aaacgctaga caaggatttc
     7021 aaaggcaagg ctggtcttca aaacattact cttatgatga tagagaagga agatttgact
     7081 ccctttatcc atcttcaaca tcatcagcag gagctgacat taaaagatgg catcgttatt
     7141 acagctaaac tcgcccagct ggcaggtgtc aaggttgggc agactttaga aattgaaggt
     7201 aaggaactaa aggtcgctgc tattactgag aactacgttg gtcactttat ttatatgagt
     7261 caggctagct atgagcaact ttacggacag ctaccccaag ccaacactta tctggtctca
     7321 ttaagggata ccagtgcaac tagtatcgaa agtcaggcgg gcttgcttat gaatcaatct
     7381 gcggtgtcca gcgttgtcca aaatgcttca gccattcgac tcttcgactc tatcgctagc
     7441 tcactcaatc agaccatgac catcttggtc atcgtatcgg ttctattagc tattgtcatc
     7501 ctttacaatc tgaccaatat caacgtagct gagagaatcc gtgaactctc cactatcaag
     7561 gttctcggtt ttcataataa tgaagtcacc ctctacattt accgtgagac gattgtgctg
     7621 tcccttgtgg gaatcgtact tggtctggta gctggtttct atttacacca atttttgatt
     7681 caaatgattt cgcctgcgac tattctcttt tatccgcagg taggctggga agtctatgta
     7741 atcccagtgg caacagtaag catcattttg accttgcttg gtttcttcgt caattattat
     7801 ttgagaaagg ttgatatgtt agaagccctg aaatctgtag agtaaggtag ttatttttag
     7861 ctgattgaac ttctatttac taatattcaa aaatcctccg tttcaaagag cagggaactc
     7921 tttgtgacag aggatttttt ctatagggct ttagcagctg caattgcggc ttcgaagttt
     7981 ggctcagaat tgatattatc cacgtattca acgtagcgaa tcgtattgtc agtatcgagg
     8041 acaaagactg cgcgtgctaa taggtgccat tcgttgatca agagggcata atcgcgcccg
     8101 aaagaatggt caaagtagtc tgaaagcata atggcattgt caaggccttc agcaccgcac
     8161 caacgttttt gagcaaaagg taggtccatt gaaacagtca atacgaccgt gttgtccagt
     8221 ccagccagtt cttcattaaa acgacgtgtt tgagttgagc agatgcctgt atcgatagaa
     8281 ggaacgacac tcaagacttt tttcttgcca tcaaaatcag ccagagattt tttagaaaga
     8341 tctgttgtag taagagaaaa atcaagcgcc ttgtcgccga cttgtagttg tttacctgta
     8401 aagcttacag gatttccgag aaaagttacc ataggatact ccaatctttt ttcttccatt
     8461 gtatctgaaa cagtcagaat tttccaatga tttgaccgga aatgtgggca tagaaaaaac
     8521 gccagctcac atgagaatga cgtttttcag aggcttattt tgccaatcct tcagcaatct
     8581 tgtcaaggtt gtatttcatc atgctgtagt agctgtcgcc ttctttacct tgttctgcga
     8641 tagaatcagt aaagatttgt gcgtagattg ggatgtttgt gtcttgagaa acagttttca
     8701 ttggacggtc atccacactt gattctacaa agagtgatgg aacttttgtt tggcgaagtt
     8761 tttcaaccaa ggtcttgatt tgttcaggag ttccctcttc ttcagtattg atttcccaga
     8821 tgtaggcact tggaacacca taggctttag agaagtattt gaatgctcct tcgctggtta
     8881 caatgagttt cttttcagca gggatcttat taaatttatc cttactttct ttatcaagtt
     8941 tgtctaactt atcagtatat tctttgagat ttttttcata gaattcttta ttgttagggt
     9001 ctttggcgct caattgtttg gcgatatttt tagcaaaaat aataccgttt tcaaggttaa
     9061 gccaagcgtg tgggtcttct tttccttttt cattttgacc ttcaaggtag ataacatcaa
     9121 cgccgtcgct gactgcgaag tagtctttgt tttcagtttt cttggcattt tctaccaatt
     9181 ttgtaaacca agcattgcca cctgtttcaa ggttgatacc gttatagaaa atcaaatcag
     9241 cctcagaagt tttcttaacg tcttcaggaa gtggttcgta ttcgtgtggg tcttgcccaa
     9301 tcggaacgat actatgaagg tcaattttgt caccagcaat atttttagta atatcagcga
     9361 tgattgagtt tgtagcaaca acttttagtt tttgaccaga agttgtatct ttttttccgc
     9421 tagcacatgc tacaagaatg attgcagaaa gaaagagaac gagtaatgta cctaattttt
     9481 tcattagatc ctccaattta ttagggcttt gccccttatt ttaacaaatg tttatttttc
     9541 agtttcaaat atcgttgttt gggagcgata aagaagctaa tgagaaagaa actagcagct
     9601 gtaagcacga tactagaacc tgccgcaaca ttaaaactat agccaataaa gagtcccaaa
     9661 actgaagcag tagctccgaa ggttgaggaa aggaaaatca tacttttcag actattagca
     9721 tacagataag cagttgcagc tggggtaatc agcatggcta caatcaggat agttccgaca
     9781 ctttgcatgg ctgtcacaga cacgagagtc aggagtacca tgagaaggta gtgatagaaa
     9841 ttgacaggca ttcccatggc tttagccaag agttcatcaa aggaagttat caagagttgc
     9901 ttgaagaaaa tccaaattaa caagaggatg gctgccccca cacccatagt aataaacata
     9961 tccgtatctt ggacggccag aatattacca aaaaggatat ggaaaaggtc agttgaactt
    10021 ttagcgacac caatcaagat gataccgagg gctaagaaag aagaaaaggt aatgccgatg
    10081 gcggtatcgc ttttgataat cgagtttcct ttgatgtagg taatgatgat ggcagctagc
    10141 aatccaaaga caatggctcc gataaagaag tcaaggccca agatgaagga gagggctaca
    10201 cctggtaaga cagcatgtga aatggcatct cccatgagtg acatcccgcg tagaataatg
    10261 aaacatccca cagctccagc tacaatcccg acgacaatag ctgttatcaa ggcattttgt
    10321 aggaaatgga atttttgcaa tccatcgata aattctgcaa tcataggtca cctccattga
    10381 aaaagagttg attaccgtaa gcttctttta gattggtttc ggtaaaagtt tcttttgttg
    10441 gaccaaaggc aatcacttct cgattgacaa gtaagacttg atcgaagtag tggggaatct
    10501 tgctgaggtc gtggtgaacg atgagaaccg tcttcccagc ttttttcaaa tctctcagcg
    10561 tattcatgat gatttcctca ctgacagagt caatcccagc aaagggttca tccaagagga
    10621 tatagtcggc ttcctgcacc aaacatctgg caatcaagac ccgctggaat tgacctccag
    10681 acagttgact aatttgacgt tcagcgtagt cagctaggcc gacgatttca agggcctctt
    10741 gcactttctt ccaatgttta gcctttaaac ttcgaaagag aggaatagag ggaaatagtc
    10801 ctaacgagac gcattccttg accttgatgg gaaagttgta gtcgatattg attttttgtt
    10861 cgacataggc aattcggtgt aaggattttt taacttcctt gtcatcgaga aatgcctgac
    10921 cttgatgtgg gataattccc agcatacctt ttaatagtgt tgatttccca gcgccgtttg
    10981 gaccaatgat gccggtaatt gttggtccat ggagcactag tgaaatatcc ttaagtgcca
    11041 acgtttcttt gtaggagaca ctgaggtttt cgatacgtat cataaacttg tattcctcct
    11101 gtctcttaat atacattaaa aaaaaaatta agtcaagtta atttttgaaa aaattaaaat
    11161 a
//
LOCUS       DAVLGK010000060        11144 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLGK010000060 DAVLGK010000000
VERSION     DAVLGK010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11144
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.061"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            225..2876
                     /locus_tag="VXE01_001936"
     CDS             225..2876
                     /locus_tag="VXE01_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEV0750792.1"
                     /translation="MKKVRKIFQKAVAGLCCISQLTAFSSIVALAETPETSPAIGKVV
                     IKETGEGGALLGDAVFELKNNTDGTTVSQRTEAQTGEAIFSNIKPGTYTLTEAQPPVG
                     YKPSTKQWTVEVEKNGRTTVQGEQVENREEALSDQYPQTGTYPDVQTPYQIIKVDGSE
                     KNGQHKALNPNPYERVIPEGTLSKRIYQVNNLDDNQYGIELTVSGKTTVETKEASTPL
                     DVVILLDNSNSMSNIRHNHAHRAEKAGEATRALVDKITSNPDNRVALVTYGSTIFDGS
                     EATVEKGVADANGKILNDSALWTFDRTTFTAKTYNYSFLNLTSDPTDIQTIKDRIPSD
                     AEELNKDKLMYQFGATFTQKALMTADDILTKQARPNSKKVIFHITDGVPTMSYPINFK
                     YTGTTQSYRTQLNNFKAKTPNSSGILLEDFVTWSADGEHKIVRGDGESYQMFTKKPVT
                     DQYGVHQILSITSMEQRAKLVSAGYRFYGTDLYLYWRDSILAYPFNSSTDWITNHGDP
                     TTWYYNGNMAQDGYDVFTVGVGVNGDPGTDEATATRFMQSISSSPDNYTNVADPSQIL
                     QELNRYFYTIVNEKKSIENGTITDPMGELIDFQLGADGRFDPADYTLTANDGSSLVNN
                     VPTGGPQNDGGLLKNAKVFYDTTEKRIRVTGLYLGTGEKVTLTYNVRLNDQFVSNKFY
                     DTNGRTTLHPKEVEKNTVRDFPIPKIRDVRKYPEITIPKEKKLGEIEFIKINKNDKKP
                     LRDAVFSLQKQHPDYPDIYGAIDQNGTYQNVRTGEDGKLTFKNLSDGKYRLFENSEPA
                     GYKPVQNKPIVAFQIVNGEVRDVTSIVPQDIPAGYEFTNDKHYITNEPIPPKREYPRT
                     GGIGMLPFYLIGCMMMGGVLLYTRKHP"
     gene            3109..5043
                     /locus_tag="VXE01_001937"
     CDS             3109..5043
                     /locus_tag="VXE01_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEV0750793.1"
                     /translation="MKSINKFLTMLAALLLTASSLFSAATVFAADNVSTAPDAVTKTL
                     TIHKLLLSEDDLKTWDTNGPKGYDGTQSSLKDLTGVVAEEIPNVYFELQKYNLTDGKE
                     KENLKDDSKWTTVHGGLTTKDGLKIETSTLKGVYRIREDRTKTTYVGPNGQVLTGSKA
                     VPALVTLPLVNNNGTVIDAHVFPKNSYNKPVVDKRIADTLNYNDQNGLSIGTKIPYVV
                     NTTIPSNATFATSFWSDEMTEGLTYNEDVTITLNNVAMDQADYEVTKGINGFNLKLTE
                     AGLAKINGKDADQKIQITYSATLNSLAVADIPESNDITYHYGNHQDHGNTPKPTKPNN
                     GQITVTKTWDSQPAPEGVKATVQLVNAKTGEKVGAPVELSENNWTYTWSGLDNSIEYK
                     VEEEYNGYSAEYTVESKGKLGVKNWKDNNPAPINPEEPRVKTYGKKFVKVDQKDTRLE
                     NAQFVVKKADSNKYIAFKSTAQQAADEKAAATAKQKLDAAVAAYTNAADKQAAQALVD
                     QAQQEYNVAYKEAKFGYVEVAGKDEAMVLTSNTDGQFQISGLAAGTYKLEEIKAPEGF
                     AKIDDVEFVVGAGSWNQGEFNYLKDVQKNDATKVVNKKITIPQTGGIGTIIFAVAGAA
                     IMGIAVYAYVKNNKDEDQLA"
     gene            5090..6271
                     /gene="rrgC"
                     /locus_tag="VXE01_001938"
     CDS             5090..6271
                     /gene="rrgC"
                     /locus_tag="VXE01_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus minor pilin RrgC"
                     /protein_id="HEV0750794.1"
                     /translation="MISRIFFVMALCFSLVWGAHAVQAQEDHTLVLQLENYQEVVSQL
                     PSRDGHRLQVWKLDDSYSYDDRVQIVRDLHSWDENKLSSFKKTSFEMTFLENQIEVSH
                     IPNGLYYVRSIIQTDAVSYPAEFLFEMTDQTVEPLVIVAKKTDTMTTKVKLIKVDQDH
                     NRLEGVGFKLVSVARDGSEKEVPLIGEYRYSSSGQVGRTLYTDKNGEIFVTNLPLGNY
                     RFKEVEPLAGYAVTTLDTDVQLVDHQLVTITVVNQKLPRGNVDFMKVDGRTNTSLQGA
                     MFKVMKEESGHYTPVLQNGKEVVVTSGKDGRFRVEGLEYGTYYLWELQAPTGYVQLTS
                     PVSFTIGKDTRKELVTVVKNNKRPRIDVPDTGEETLYILMLVAILLFGSGYYLTKKPN
                     N"
     gene            6609..7511
                     /gene="srtC-1"
                     /locus_tag="VXE01_001939"
     CDS             6609..7511
                     /gene="srtC-1"
                     /locus_tag="VXE01_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-1"
                     /protein_id="HEV0750795.1"
                     /translation="MVKTKKQKRNNLLLGVVFFIGMAVMAYPLVSRLYYRVESNQQIA
                     DFDKEKATLDEADIDERMKLAQAFNDSLNNVVSGDPWSEEMKKKGRAEYARMLEIHER
                     MGHVEIPVIDVDLPVYAGTAEEVLQQGAGHLEGTSLPIGGNSTHAVITAHTGLPTAKM
                     FTDLTKLKVGDKFYVHNIKEVMAYQVDQVKVIEPTNFDDLLIVPGHDYVTLLTCTPYM
                     INTHRLLVRGHRIPYVAEVEEEFIAANKLSHLYRYLFYVAVGLIVILLWIIRRLRKKK
                     KQPEKALKALKAARKEVKVEDGQQ"
     gene            7498..8391
                     /gene="srtC-2"
                     /locus_tag="VXE01_001940"
     CDS             7498..8391
                     /gene="srtC-2"
                     /locus_tag="VXE01_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-2"
                     /protein_id="HEV0750796.1"
                     /translation="MDNSRRSRKKGTKKKKHPLILLLIFLVGFAVAIYPLVSRYYYRI
                     ESNEVIKEFDETVSQMDKAELEERWRLAQAFNATLKPSEILDPFTEQEKKKGVSEYAN
                     MLKVHERIGYVEIPAIDQEIPMYVGTSEDILQKGAGLLEGASLPVGGKNTHTVITAHR
                     GLPTAELFSQLDKMKKGDIFYLHVLDQVLAYQVDQIVTVEPNDFEPVLIQHGEDYATL
                     LTCTPYMINSHRLLVRGKRIPYTAPIAERNRAVRERGQFWLWLLLGAMAVILLLLYRV
                     YRNRRIVKGLEKQLEGRHVKD"
     gene            8378..9229
                     /gene="srtC-3"
                     /locus_tag="VXE01_001941"
     CDS             8378..9229
                     /gene="srtC-3"
                     /locus_tag="VXE01_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-3"
                     /protein_id="HEV0750797.1"
                     /translation="MSRTKLRALLGYLLMLVACLIPIYCFGQMVLQSLGQVKGHATFV
                     KSMTTEMYQEQQNHSLAYNQRLASQNRIVDPFLAEGYEVNYQVSDDPDAVYGYLSIPS
                     LEIMEPVYLGADYHHLGMGLAHVDGTPLPLDGTGIRSVIAGHRAEPSHVFFRHLDQLK
                     VGDALYYDNGQEIVEYQMMDTEIILPSEWEKLESVSSKNIMTLITCDPIPTFNKRLLV
                     NFERVAVYQKSDPQTAAVARVAFTKEGQSVSRVATSQWLYRGLVVLAFLGILFVLWKL
                     ARLLRGK"
     gene            complement(9302..10578)
                     /locus_tag="VXE01_001942"
                     /pseudo
     CDS             complement(9302..10578)
                     /locus_tag="VXE01_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(10693..10842)
                     /locus_tag="VXE01_001943"
     CDS             complement(10693..10842)
                     /locus_tag="VXE01_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750798.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFMAL"
     gene            complement(10835..11119)
                     /locus_tag="VXE01_001944"
     CDS             complement(10835..11119)
                     /locus_tag="VXE01_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750799.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
BASE COUNT         3560 a         1870 c         2521 g         3193 t
ORIGIN      
        1 actatactat attgtataca agtgtgtcat tgccaggttg agaagatagc tataacgcac
       61 ttttatacgc ttttgctacg tttgttagtg aacggattaa ctcagtgaga taaattttat
      121 cagaacataa gtaatccgtt tcttcgtgta tacagattga aagtacctat gaatcataga
      181 aggattaact tgttctatga ataatgctta acagggagac acacatgaaa aaagtaagaa
      241 agatatttca gaaggcagtt gcaggactgt gctgtatatc tcagttgaca gctttttctt
      301 cgatagttgc tttagcagaa acgcctgaaa ccagtccagc gataggaaaa gtagtgatta
      361 aggagacagg cgaaggagga gcgcttctag gagatgccgt ctttgagttg aaaaacaata
      421 cggatggcac aactgtttcg caaaggacag aggcgcaaac aggagaagcg atattttcaa
      481 acataaaacc tgggacatac accttgacag aagcccaacc tccagttggt tataaaccct
      541 ctactaaaca atggactgtt gaagttgaga agaatggtcg gacgactgtc caaggtgaac
      601 aggtagaaaa tcgagaagag gctctatctg accagtatcc acaaacaggg acttatccag
      661 atgttcaaac accttatcag attattaagg tagatggttc ggaaaaaaac ggacagcaca
      721 aggcgttgaa tccgaatcca tatgaacgtg tgattccaga aggtacactt tcaaagagaa
      781 tttatcaagt gaataatttg gatgataacc aatatggaat cgagttgacg gttagtggta
      841 aaacgacggt tgaaacgaaa gaagcctcta ctccgctaga tgttgttatt ctattagata
      901 actccaatag tatgagtaat attcgacata atcatgccca tcgagcggaa aaagcgggag
      961 aagcgacacg agcccttgta gataagatta cctccaatcc agataatcga gtagcacttg
     1021 tgacttatgg ctcaactatc tttgacggtt cagaagctac tgtggaaaaa ggggtagcag
     1081 atgcgaacgg aaaaatattg aatgactcag ctttatggac gttcgatcgt acgacgttta
     1141 cagctaaaac ttataattat agctttttaa atctcacatc agatcctact gatattcaaa
     1201 ctattaagga taggattcca tcagatgcag aggaattgaa caaagacaaa ttgatgtatc
     1261 aattcggcgc gacttttacc cagaaggctt tgatgaccgc tgatgatatc ttgacaaagc
     1321 aggcaagacc aaacagtaaa aaggttattt tccacattac agatggtgtt ccgactatgt
     1381 catatccaat taattttaaa tatacaggaa cgacgcaatc gtacagaact cagctgaata
     1441 attttaaagc aaaaactcca aatagtagcg ggatattact ggaggacttt gttacatggt
     1501 cagcagatgg tgaacataag attgttcgtg gagatggtga aagttatcag atgtttacga
     1561 agaaacctgt aacagaccaa tacggagttc atcaaatact ttcaatcacc tccatggagc
     1621 agagagctaa attagtttca gcgggatata ggttctatgg aactgacttg tatttatatt
     1681 ggcgtgatag tattctagcc tatccattta actctagtac cgattggatt accaaccatg
     1741 gtgaccctac gacttggtat tataacggaa atatggctca ggatggctat gatgtcttca
     1801 ctgttggggt tggtgtaaac ggggatcctg gtacggatga agcaacggct actagattta
     1861 tgcagagcat ctctagttct cctgacaact acactaacgt agcagatcca tctcagattt
     1921 tacaagaatt gaatcgctac ttctatacta tcgtcaatga gaagaaatct atcgaaaatg
     1981 gtacgattac agacccgatg ggtgaactaa ttgatttcca attgggagca gatggaaggt
     2041 ttgatccagc ggattacact ttaactgcaa acgatggtag ttcgttggtg aataatgtcc
     2101 ctactggggg accacaaaat gatggtggct tgctaaaaaa tgcaaaagtg ttctatgata
     2161 cgactgagaa aaggattcgt gtaacaggtt tgtaccttgg aacgggtgaa aaagttacat
     2221 tgacttataa tgttcgcttg aatgaccaat ttgtaagcaa taaattctat gacacgaatg
     2281 gtcgaacaac cctacaccct aaggaagtag aaaagaacac agtgcgcgac ttcccgattc
     2341 ctaagattcg tgatgtacga aagtatccag aaatcacaat tccaaaagag aaaaaacttg
     2401 gtgaaattga gtttattaag atcaataaga atgataaaaa accactgaga gatgcggtct
     2461 ttagtcttca aaaacaacat ccggattatc cagatattta tggagctatt gatcaaaatg
     2521 gcacttatca aaatgtgaga acaggtgaag atggtaagtt gacctttaaa aatctgtcag
     2581 atgggaaata tcgattattt gaaaattctg aaccagctgg ttataaaccc gttcaaaata
     2641 agcctatcgt tgccttccaa atagtaaatg gagaagtcag agatgtgact tcaatcgttc
     2701 cacaagatat accagcgggt tacgagttta cgaatgataa gcactatatc acaaatgagc
     2761 caattcctcc aaaaagagaa tatcctcgaa ctggtggtat cggaatgttg ccattctatc
     2821 tgataggttg catgatgatg ggaggagttc tattatacac acggaaacat ccgtaaagtg
     2881 tagcaatgag aaatgataat atcgatactc tgagcgatac ttttaagaag tagcactcaa
     2941 gaagagattt aagtttactt ggtgaaaaca gttttcttcg ccaagtaaac caccattgaa
     3001 aggggagatg ttttcgaaaa cttgcacaga aaaaaggatt attattgtca tgtgtaattc
     3061 attacattgc tcacagttga ttttaagaga tatgaataag gagaaatcat gaaatcaatc
     3121 aacaaatttt taacaatgct tgctgcctta ttactgacag cgagtagcct gttttcagct
     3181 gcaacagttt ttgcggcgga caatgttagt acagcaccag atgctgttac taaaacttta
     3241 acaatccata agttactgct ctcagaagat gatttaaaga cttgggatac aaacggtcct
     3301 aaaggatatg atggaactca atctagttta aaagatttaa ctggagttgt agctgaggaa
     3361 attccaaatg tatactttga attacaaaag tataatttga ctgatggtaa ggaaaaagaa
     3421 aatcttaaag atgatagtaa atggacaaca gttcatggtg gtttgacaac taaagatgga
     3481 cttaaaattg aaaccagtac tcttaaaggt gtgtatcgta ttcgtgagga tagaacaaag
     3541 actacctatg ttggtcctaa tgggcaagta ttaacaggtt caaaagccgt acctgctctt
     3601 gtaactcttc cacttgttaa caataatggt acagtaattg atgcacatgt tttccctaaa
     3661 aattcatata ataaaccagt tgtagataaa agaattgctg atactttgaa ttataacgat
     3721 caaaatggtc tgtctatcgg tactaaaatc ccatatgttg ttaatacaac aattccaagt
     3781 aatgcaacat ttgcaacttc attttggtca gatgaaatga cagaaggtct aacttataat
     3841 gaagatgtaa caattacttt gaataatgta gctatggatc aagctgatta tgaagtcact
     3901 aaaggaatta atggctttaa cttaaaatta acagaagcag gtttagctaa aattaatggt
     3961 aaggatgcag accaaaaaat ccaaattact tactcagcta ctttgaactc acttgctgtt
     4021 gcagacattc ctgaaagtaa cgatattaca tatcattacg gaaatcatca agatcatggg
     4081 aatactccaa aaccaactaa acctaataat ggtcaaatta cagtaactaa gacatgggac
     4141 agtcaacctg ctcctgaggg ggtgaaagcg actgttcaac ttgtaaatgc caagactggt
     4201 gagaaagtcg gtgctcctgt agaactttca gaaaataatt ggacatatac ttggagtggt
     4261 ctagataatt ctattgaata caaagttgaa gaagaatata atggatactc agctgaatac
     4321 acagtagaga gcaaagggaa gttgggggta aaaaactgga aagataataa cccagctcca
     4381 atcaatcctg aagaaccacg tgtaaaaaca tacggtaaaa agtttgtcaa agtagaccaa
     4441 aaagatactc gtctagaaaa tgcgcagttc gttgttaaaa aagcagatag caataaatat
     4501 attgccttta agtcaactgc acaacaagct gcagatgaaa aagcagcagc aactgcaaaa
     4561 caaaaattgg atgcagcggt agcagcttac acaaatgctg cagataagca agccgctcaa
     4621 gctctagtag atcaagcaca gcaagaatac aatgtagctt acaaagaagc caaatttggt
     4681 tatgttgaag tagctggaaa agatgaagca atggttctta cttctaatac ggatggtcaa
     4741 ttccaaattt caggtcttgc tgctggtact tataaattag aagaaattaa agctccagaa
     4801 ggttttgcga aaattgatga tgtagaattt gttgttggag caggttcttg gaatcaaggt
     4861 gagtttaatt acttaaaaga tgttcaaaag aatgacgcta caaaagtagt caacaaaaaa
     4921 atcactatcc cacaaacggg tggtattggt acaattatct ttgctgtagc gggggctgcg
     4981 attatgggta ttgcagtgta cgcatatgtt aaaaacaaca aagatgagga tcaacttgct
     5041 taagtaagag agaaaggagc cattgatgac aatgcagaaa atgcagaaaa tgattagtcg
     5101 tatcttcttt gttatggctc tgtgtttttc tcttgtatgg ggtgcacatg cagtccaagc
     5161 gcaagaagat cacacgttgg tcttgcaatt ggagaactat caggaggtgg ttagtcaatt
     5221 gccatctcgt gatggtcatc ggttgcaagt atggaagttg gatgattcgt attcctatga
     5281 tgatcgggtg caaattgtaa gagacttgca ttcgtgggat gagaataaac tttcttcttt
     5341 caaaaagact tcgtttgaga tgaccttcct tgagaatcag attgaagtat ctcatattcc
     5401 aaatggtctt tactatgttc gctctattat ccagacggat gcggtttctt atccagctga
     5461 atttcttttt gaaatgacag atcaaacggt agagcctttg gtcattgtag cgaaaaaaac
     5521 agatacaatg acaacaaagg tgaagctgat aaaggtggat caagaccaca atcgcttgga
     5581 gggtgtcggc tttaaattgg tatcagtagc aagagatggt tctgaaaaag aggttccctt
     5641 gattggagaa taccgttaca gttcttctgg tcaagtaggg agaactctct atactgataa
     5701 aaatggagag atttttgtga caaatcttcc tcttgggaac tatcgtttca aggaggtgga
     5761 gccactggca ggctatgctg ttacgacgct ggatacggat gtccagctgg tagatcatca
     5821 gctggtgacg attacggttg tcaatcagaa attaccacgt ggcaatgttg actttatgaa
     5881 ggtggatggt cggaccaata cctctcttca aggggcaatg ttcaaagtca tgaaagaaga
     5941 aagcggacac tatactcctg ttcttcaaaa tggtaaggaa gtagttgtaa catcagggaa
     6001 agatggtcgt ttccgagtgg aaggtctaga gtatgggaca tactatttat gggagctcca
     6061 agctccaact ggttatgttc aattaacatc gcctgtttcc tttacaatcg ggaaagatac
     6121 tcgtaaggaa ctggtaacag tggttaaaaa taacaagcga ccacggattg atgtgccaga
     6181 tacaggggaa gaaaccttgt atatcttgat gcttgttgcc attttgttgt ttggtagtgg
     6241 ttattatctt acgaaaaaac caaataactg atattcaatg tacatcatta tgaaaaagat
     6301 agcaggctga agggaagacc agagtactct gaggtgatgt taatcaggaa tcatggtgat
     6361 gtggcatgaa tcacaataac ggatatgagg ctgggcagat tgtgccagcc tcattgtggg
     6421 ttattgtttg taaaacgata ggactggtct ggtaatcatt ttaggaatgg acaggactgg
     6481 gattctgatt taaaatggat ggtgaatcag aaagaaatga gattttctcg tttctcttag
     6541 cagataggat tgtctgttag gaaaagcgat aaaatgatga gtttgaagat aaagggatgc
     6601 tgataaaaat ggtaaaaaca aaaaagcaaa aacgaaataa tctcctatta ggagtggtat
     6661 ttttcattgg aatggcggta atggcgtatc cgctggtgtc tcgcttgtat tatcgagtgg
     6721 aatcaaatca acaaattgct gactttgata aggaaaaagc aacgttggat gaggctgaca
     6781 ttgatgaacg aatgaaattg gcacaagcct tcaatgactc tttgaataat gtagtgagtg
     6841 gcgatccttg gtcggaagaa atgaagaaaa aagggcgagc agagtatgca cgtatgttag
     6901 aaatccatga gcggatgggg catgtggaaa tccccgttat tgacgtggat ttgccggttt
     6961 atgctggtac tgctgaagag gtattgcagc aaggggctgg gcatctagag ggaacttctc
     7021 tgccgatcgg aggcaattcg acccatgcgg tgattacggc acatacaggt ttgccaacag
     7081 ctaagatgtt tacggatttg accaaactta aagttgggga taagttttat gtgcacaata
     7141 tcaaggaagt gatggcctat caagtggatc aagtaaaggt gattgagccg acgaactttg
     7201 atgatttatt gattgtacca ggtcatgatt atgtgacctt gctgacttgt acgccataca
     7261 tgatcaatac ccatcgtcta ttggttcggg ggcatcggat accgtacgta gcagaggttg
     7321 aggaagaatt tattgcagca aacaaactca gtcatctcta tcgctacctg ttttatgtgg
     7381 cagttggttt gattgtgatt cttttatgga ttattcgacg cttgcgcaag aagaaaaaac
     7441 aaccggaaaa ggctttgaag gcgctgaaag cagcaaggaa ggaagtgaag gtggaggatg
     7501 gacaacagta gacgttcacg aaaaaaaggc acaaaaaaga agaaacatcc gctgatcctt
     7561 cttctgattt tcttagtagg attcgccgtt gcgatatatc cattggtgtc tcgttattat
     7621 tatcgtattg agtcaaacga ggttattaaa gagtttgatg agacggtttc ccagatggat
     7681 aaggcagaac ttgaggagcg ttggcgcttg gctcaagcct tcaatgcgac cttgaaacca
     7741 tctgaaattc ttgatccttt tacagagcaa gagaaaaaga aaggcgtctc agaatatgcc
     7801 aatatgctaa aggtccatga gcggattggc tatgtggaaa ttcctgcgat tgatcaggaa
     7861 attccgatgt atgtcggaac gagtgaggac attcttcaga aaggggcagg gctgttagaa
     7921 ggggcttcgc tgcctgttgg aggtaaaaat acccatacag tgatcactgc tcacagagga
     7981 ttgccaacgg cagaattgtt cagtcaattg gataagatga aaaaagggga tatcttttat
     8041 cttcacgttt tagatcaggt gttggcctac caagtggatc agatagtgac ggtggagccg
     8101 aatgactttg agcctgtctt gattcaacat ggggaagatt atgcgacctt gttgacttgt
     8161 acaccgtata tgattaacag tcatcgtctg ttggtacgtg ggaagcggat tccgtatacg
     8221 gcaccaattg cagagcggaa tcgagcggtg agagagcgtg ggcaattctg gttgtggtta
     8281 ttactaggag cgatggcggt catccttctc ttgctgtatc gcgtgtatcg taatcgacgg
     8341 attgtcaaag gactagaaaa gcaattggag gggcgtcatg tcaaggacta aactacgagc
     8401 cttattggga tacttgttga tgttggtagc ctgtttgatt cctatttatt gttttggaca
     8461 gatggtgttg cagtctcttg gacaggtgaa aggtcatgct acatttgtga aatccatgac
     8521 aactgaaatg taccaagaac aacagaacca ttctctcgcc tacaatcaac gcttggcttc
     8581 gcaaaatcgc attgtagatc cttttttggc ggagggatat gaggtcaatt accaagtgtc
     8641 tgacgaccct gatgcagtct atggttactt gtctattcca agtttggaaa tcatggagcc
     8701 ggtttatttg ggagcagatt atcatcattt agggatgggc ttggctcatg tggatggtac
     8761 accgctgcct ctggatggta cagggattcg ctcagtgatt gctgggcacc gtgcagagcc
     8821 aagccatgtc tttttccgcc atttggatca gctaaaagtt ggagatgctc tttattatga
     8881 taatggccag gaaattgtag aatatcagat gatggacaca gagattattt taccgtcgga
     8941 atgggaaaaa ttagaatcgg ttagctctaa aaatatcatg accttgataa cctgcgatcc
     9001 gattcctacc tttaataaac gcttattagt gaattttgaa cgagtcgctg tttatcaaaa
     9061 atcagatcca caaacagctg cagttgcgag ggttgctttt acgaaagaag gacaatctgt
     9121 atcgcgtgtt gcaacctctc aatggttgta ccgtgggcta gtggtactgg catttctggg
     9181 aatcctgttt gttttgtgga agctagcacg tttactacga gggaaataaa aagaaatgaa
     9241 aggaaagcta aggctgttcc tttttccggc tctttgtcaa ctgtagtggg ttgaaaaaaa
     9301 gctaagctcg agaaaggaca aattttgtcc tttctttttt gatattcaga gcgataaaaa
     9361 tccgtttttt gaagttttca aagtttcgaa aaccaaaggc attgcgcttg ataagtttga
     9421 tgagattatt ggtcgcttcc agtttggcat tagaatagtg tagttgaagg gcgttgataa
     9481 tcttttcttt atctttgagg aaggttttaa agacagtctg aaaaatagga tgaacctgct
     9541 taagattgtc ctcaataagt ccgaaaaatt tctctggttc cttattctgg aagtgaaaaa
     9601 gcaagagctg atagagttga tagtggtgtt tcaagtcttc cgaatagctc aaaagcttgt
     9661 ttaaaatctc tttattggtt aagtgcatac gaaaaatagg acgataaaat cgcttatcac
     9721 tcagtttacg gctatcctgt tgaatgagtt tccagtagcg cttgatagcc ttgtattcat
     9781 gggattttcg atgaaactga ttcatgattt gaacacgcac acgactcata gcacggctaa
     9841 gatgttgtac aatgtgaaag cgatcaagaa cgattttagc acacgggaaa agttgtctag
     9901 ctaagtcata gtaaggacta aacatatcca tagtaatgat tttgacgcga catcggacgg
     9961 ctctatcata tttaagaaag tgatctcgga tgacagcttg tgttctacct tcaagaacag
    10021 tgatgatatt gagattgtta aaatcttgcg caataaagct catctccatc tcccgattga
    10081 aacagtcact ccccggactg tttcaacgtc ccaggacata atctcaggaa gacgcgaaaa
    10141 atcatgctca aagtgagaat cattgagctt gcgaatgaca gttgaagttg aaatggccag
    10201 ctgatgagca atatcggtca tagaaatctt ctcaatcaac ttttgcgcaa ttttttggtt
    10261 ggtaatacga ggaatttgat gattcttctt gacgatagaa gtttcagcga ccatcatttt
    10321 tgaacagtga tagcacttga aacggcgttt tctaaggaga attctagtag gtataccagt
    10381 cgtttcaaga taaggaattt tagaaggttt ttgaaagtca tatttcttca attggtttcc
    10441 gcactcaggg caagatgggg cgtcgtagtc cagtttggcg atgatttcct tgtgtgtatc
    10501 cttattgatg atgtctaaaa tctggatatt agggtcttta atgtctagta attttgtgat
    10561 aaaatgtaat tgttccatat gattctttct aatgagttgt tttgtcgctt ttcattatag
    10621 gtcatatggg actttttttc tacacaaaaa taggctccat aatatccata ggggatttac
    10681 ccactacaaa tattatagag ccataaaagc atcaacatct tgtgtggcac gtaaaccatg
    10741 atattctaag acataaccat cgacacagat aattgttaaa gtcagatttt cctgaattaa
    10801 ttccttattt agggcttgga agaccggttt cattttatcc atgtttgtat ttctccatca
    10861 atttttgaac attggttaac ttagcaggtt tatttaatga aatcacatat ttatgagttg
    10921 gagtatgctc ttgaaaggca tacttcaagc taattttttg aaaacgggtt agttctttgg
    10981 agtctagcaa cttttctaca tcttggtttg ttaaataaga atagtcttca aaaataactt
    11041 ttcgcaaata gcgaaaccaa tggcttgcgt tgaattgtga ttgtttggat gcctgtatca
    11101 tataatcgta ccaatccatt gtcttcctcc tataaaattt agtt
//
LOCUS       DAVLGK010000061        10458 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLGK010000061 DAVLGK010000000
VERSION     DAVLGK010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10458
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.062"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(300..1199)
                     /gene="galU"
                     /locus_tag="VXE01_001945"
     CDS             complement(300..1199)
                     /gene="galU"
                     /locus_tag="VXE01_001945"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV0750800.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(1221..2237)
                     /locus_tag="VXE01_001946"
     CDS             complement(1221..2237)
                     /locus_tag="VXE01_001946"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0750801.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            2449..2829
                     /locus_tag="VXE01_001947"
     CDS             2449..2829
                     /locus_tag="VXE01_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0750802.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            complement(3003..3428)
                     /locus_tag="VXE01_001948"
     CDS             complement(3003..3428)
                     /locus_tag="VXE01_001948"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0750803.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(3496..4146)
                     /gene="phoU"
                     /locus_tag="VXE01_001949"
     CDS             complement(3496..4146)
                     /gene="phoU"
                     /locus_tag="VXE01_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0750804.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(4161..4913)
                     /gene="pstB"
                     /locus_tag="VXE01_001950"
     CDS             complement(4161..4913)
                     /gene="pstB"
                     /locus_tag="VXE01_001950"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0750805.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(4915..5730)
                     /gene="pstA"
                     /locus_tag="VXE01_001951"
     CDS             complement(4915..5730)
                     /gene="pstA"
                     /locus_tag="VXE01_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0750806.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(5723..6586)
                     /gene="pstC"
                     /locus_tag="VXE01_001952"
     CDS             complement(5723..6586)
                     /gene="pstC"
                     /locus_tag="VXE01_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0750807.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     IYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(6704..7579)
                     /locus_tag="VXE01_001953"
     CDS             complement(6704..7579)
                     /locus_tag="VXE01_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV0750808.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(7746..9077)
                     /locus_tag="VXE01_001954"
     CDS             complement(7746..9077)
                     /locus_tag="VXE01_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV0750809.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(9078..9785)
                     /locus_tag="VXE01_001955"
     CDS             complement(9078..9785)
                     /locus_tag="VXE01_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0750810.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKT
                     PQFIRTIRGYGYKFKEL"
     gene            complement(9869..10354)
                     /locus_tag="VXE01_001956"
     CDS             complement(9869..10354)
                     /locus_tag="VXE01_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0750811.1"
                     /translation="MAPTDKEDLIRTLELAPHVKGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWESTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            10340..10458
                     /locus_tag="VXE01_001957"
                     /pseudo
     CDS             10340..10458
                     /locus_tag="VXE01_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         3152 a         2096 c         2071 g         3139 t
ORIGIN      
        1 gttgatttaa tttaaccatg actactccaa cagttaagtc aaatttaaaa ttatttatta
       61 ttttggaacc attcgaaaca acatagcaaa gttaaaataa ggctttgtcc gtacacaact
      121 tgaaaaagtg cgcaccgatt cggtgctttt ttgttttact atattaattt attctactct
      181 tattttaatg aaaaaacaaa tacaagtata gcgttttcat tagtttttat taaataggta
      241 gattcaagta gagaatttac ttaatttatg tgtggctaat ctttatataa atgattttgt
      301 tattccttct cagtcaattc ttttccaagt tggatgaggt aattcttcaa atcatctttg
      361 acttgtgggt gtttgagggc gtagtcgatg gatgttttca tgaagccaaa cttgtctccg
      421 acatcgtaac gagccccttt gaactcacga gcaaatacac gttgtgtttt attgagggtg
      481 tcgattgcat ctgtcagctg aatttcattt cctgcacctg gagcttgctt ttcgagaatc
      541 tcaaaaattt caggcgtgag gaggtagcgt ccgataatag caaggtcgct aggagcgtcc
      601 tctggagctg gtttttcaac aaaggtttca acactgtaaa gaccatcttt tccttcgcct
      661 tgcggagcaa taaccccgta agcagatact tcgtcatgag ggactggcat gacagcgata
      721 gtagacgcgt gggtacgctc gtagtcatcc atgagttgtt tggtaagtgg aacagccttt
      781 tcgtctgtga tatccatcaa gtcatcacca agcataacga caaaaggttc atttccgacg
      841 aaagccttgg cttgcaaaac agcatctccg agaccgcgtg gatgagtttg gcggataaaa
      901 tgcagacgca tgccagttgt ttcatcaact agcttcaaaa gatctgtttt ccctttttct
      961 ttgaggttat attccaattc gaagtttgaa tcaaagtggt cctcaataga acgttttgat
     1021 ttaccagtga caactagaat atcttcaata cctgatttga gagcctcttc cacgataaac
     1081 tggatagttg gtttgtctac gattggcaac atttctttgg caagggcctt ggttgctggt
     1141 aaaaatcgag ttcctagtcc agcagcaggg atgactgcct ttctaacttt tgatgtcata
     1201 aaaatccttt ctatagaggg ttaagaccac tcattttctg ctttaaattc attgttcatg
     1261 atgtcataaa tggcatcttt gatattggtt ccgtgataaa taacttggta aatagcctgt
     1321 gtaatgggca tatagactcc aagttcttgg gctagttcat aggctgctcg agtcgttgaa
     1381 attccttcga ttaccatgcc catattagct tctatatcag ctagggattc tcctcgtccg
     1441 agagcatctc cagctctcca gttacgagag tggatggaag ttcccgttac gatcaaatct
     1501 cccacaccag ataagccgct ataggtcaat ggactggccc cgagtgctac ccctaggcgg
     1561 gtgatttctg ctaaacctcg agcgatgatg gctgccttag cattatcacc aaatccaaga
     1621 ccatgtaaag ctccagcacc gacagcaata atatttttaa gagcaccagc agtttcaacc
     1681 ccgataacat ccgtattggt ataaagtcgg aagtagtgat tactaaatag ctcctgaacg
     1741 tattgagctg tttgtaaatc tttagaagca gcagtgatta aagttaggtc acgcacaatg
     1801 gtttcttccg catgactagg ccctgaaaca acgacaatat cactgcggag ctgttcagga
     1861 atttcttctt caaggatagt tgataatcgt ttatggctat caggttctaa tccctttgaa
     1921 gcgtgcatga tgatagcctt atggtccaag gtttgtgcaa cttgttgggc aacaagtcgt
     1981 gtcacttttg ttgggacaac aaacaaaatc gcatccacat ctttcaatgt ttctgctaag
     2041 tcggtgtagg caatgatatt ttcatctaga acgacatctt taaagtagtg cttgttagta
     2101 tgataggtat taatttcatt gatttgctcg ggaagatttc cccaaatacg tacctcgtgt
     2161 ccattgtcat ttaagacttg tgaaagggca gttccccaag aaccaggccc caagacggcg
     2221 acggtttgtt tttccatgat ttcctccttg atagagttct ttccattatt ctatcatatt
     2281 ctagaggatt ttgcacttgc attactgggg tatggtggaa aaatacacaa agaccgagat
     2341 gaagggataa actcttagtc tttagttaaa gtgagaagaa atctgataga tagtttgatt
     2401 cagtatatgc ttataataga ggtaaacaac tcaggaggtt cttgtaggtt gcgagagttt
     2461 ggcgaaaaaa ttaaaagatt acgtttggct aaaaaaatca gtcgttcaga attttgtggt
     2521 gatgagtctg aattaagtat ccgtcaatta attagaattg aaaatggaga atccagacca
     2581 acactaacaa agttaaaata tatcgctgaa cgtttggggg ttgaggatta caagttgatg
     2641 ccaagttata tagagttgga taaggaatac ctagaattga agtatttctt gatgaggact
     2701 cctacatacg aagatgaaac tatcgcccaa aagaaagaga gtgttttgat aagatttttg
     2761 aagagtatta tgataggcta cctgaggaag aaagatttat catcccaaat tattcatatc
     2821 tggcactaac gaactacaca gttcaaaaat taccagaaaa gctagttgaa atactgtcct
     2881 tctggtgatt ttgcttaatt tctgatgtta gagacataat tgaggagatt tgtcttgatt
     2941 ttttcctaaa aaagggcaga ctcctccctt ggtttgatgc tcgattttta aaataaggtg
     3001 acttattctg ttaggcatgt tttcccctgc cctctagctc tatatggaac agggagtatc
     3061 agatttatct ggcagattgt atcaaataag gcttgaaact gttttgaata ggcatataga
     3121 cttgagaatt tgagaatatg tcgtctagca gtagagacat attttccggc aatatgaagg
     3181 aagagacgtc gaaaacgctt gatagtcaag gcctttactt catcaccagc tagctgcttt
     3241 aaaaagaggt agagattata agccagacag cccatcatca tacgtacttc attcttaatc
     3301 atggtcgaac tatctgtctt atccccaaag aatcctgctt tcctttcttt gataaagttt
     3361 tcagcattcc ctcgttcacg atagaattga aacagctcct cactatctac actgcttaaa
     3421 ttggtcaaat gaactttttt acaaccataa aaaagagcac ttaatcgtac tcttctcttt
     3481 taaggattag ttgaattaat tcaaatccac tagttctcct gtttctaggt agactaggcg
     3541 ttcacaaatg ttagcaatgt aatcagcgaa gcgttccaga tgccctatga tataaaggta
     3601 ttgtgttcca ttgggaattg aggtttcttg gtctttcata agtccaatga tttcctttga
     3661 taaggcataa taatattggt caatctgttc atctttttga gcaatactaa tagcttttga
     3721 ggcttggtgc aaaggaaagg caaccaataa atcggatagc atgctgaggg ataatttacc
     3781 catttggtgt aactgttctt cgtcaggggc tagttgattt tcttttagtt gcaaaacagc
     3841 tttagcaatg cctgccatat ggtctcccat acgttcaagg tctgaacaag aagacatgat
     3901 gctaatcaca aatcgaaggt cagacacttg tggctgctgc aaggccaaca aacgggcaca
     3961 ggtcaattcg atagcgcttt gaccttggtt gatagcatga tccttattga taattagctc
     4021 tgccatctcc ttgtctttgg aggctaaggc cagtaaggct tttgaagctg tttcaaggac
     4081 aagttgccct agtcctaaaa aggattgttc taattcatgc aattctaagt caaattgatt
     4141 tctcataggt ttttccttcc ttatccgaac cgtcctgaaa tatagtcttc tgtgcgctga
     4201 tcttttggat tggtaaacac gtcaacggta tctccaaatt cgcaaatttc tcctgttaag
     4261 aaaaaagcag ttttatctga aatacgtgaa gcttgttgca tgttatgggt aacaatgata
     4321 atcgtataat ccttttttag ttgctgaatg aggtcttcaa tttttaaagt ggagataggg
     4381 tctaaggctg aagtcggctc atccattaac agaatatcag gttctactgc taaagctcgc
     4441 gcaatgcaaa ggcgttgctg ctgaccgcca gataaggaca tggcactctt tttaagatca
     4501 tctttgactt cttcccaaat ggctgcccct tttaaagatt tctccactaa ggcatctaat
     4561 tgttttttgt ctcgaatacc atgtgtcctt ggaccataag ccacgttatc atagatagac
     4621 atggcaaagg gattaggctg ttgaaaaacc atccctacac gcttacgtag ctgattaagg
     4681 ttgaatttgc tactataaat atcttgctca tctaagagga cttggccttc aatatggcaa
     4741 gaaggaacca aatcgttcat ccggttaagg gtttttagaa aagttgattt accacaacca
     4801 gatgggccta tcaaggcagt aatctgtctt tctggtaatt gaatcgaaat attttttaag
     4861 gcttgaaaat ccccgtaaaa taagtctagg tgtctgactg aaaatgttcc catactagga
     4921 agctcctttc acaagttttc gagataataa gcttgataga gtatttatca ttaaaacagt
     4981 aataatcaaa atcacaccgg tagcataggc ttcattgaca tgtagcccct cacttgacag
     5041 catatacata tgcagggcta gagaacgacc tgaagacatg agactacttg gcgtattggt
     5101 agaggtacct aatgtataca tgagggcagc tgtctcacca acgatacggc caatagctag
     5161 tatcactcca gctaaaatac ctggcatggc aactggtaga acaattctaa aaacagtccg
     5221 taacttacct gccccaagtc cataacttgc ttgacgcatg ctatcactaa cagataaaag
     5281 ggcttcttct gttgagcgaa taatgactgg caacaccatg atgactgagg ttaagattcc
     5341 tgataacaga gagtattgaa aacctaagaa gactacaaag aagagcatgc caaacagacc
     5401 aaaaacaatg gaaggaatcc cagacaaggt atctgaggcc aatcgcatga ttttaacaca
     5461 aagggaatct ttttttgtat attccacaag ataaaaacca gcaaaaatcc ctatgggcaa
     5521 ggctaaaaga agagcaccaa agaccagaat aacggtggaa ataatcgctg gcataaggga
     5581 aatgttctca gaagtataag tccaagaaaa gagggataga cttagatgag gtaagccttt
     5641 gatgaggata aaaccaatga ttaaaaagag agagccaaag gttaaagctg aaaaacaata
     5701 aacgagaagt tttagcaggt atttactcat aagatgattt tcctttcaag taggcaaagt
     5761 aggcattaat caagagaata aggaaaaaga gaactgctga ggttgcaata agggcttccc
     5821 tatgctgacc tgatgcgtaa gccatttcca gaacaatatt ggttgttaag gttctggttc
     5881 ctgaaaagag tccacttgga ataatcggct ggttgcctgc caccaaaata actgccatgg
     5941 tttcacctac tgcgcgaccg attcctaaaa taactgctga taaaatacca gatctcgcag
     6001 ctggcaagat gacactaaaa atactccgtt catgactagc tcctagagcc aagctaccag
     6061 aataatacgt tttgggaact gttcggatag cagattctga caaactgata atggttggca
     6121 aaatcattat tcctaatagt aacgaagcgg ttaggacact catgccattt cctaaaaagc
     6181 ttctaatcca aggcaccaat aattgtaggc cgaaaaaacc ataaacaata gatggaatgg
     6241 ccgccatcaa gttgatagct gattttaaga agccatagat gggctttgga caataataaa
     6301 ccataaacac cgatgtcaag atgcctgttg gcaccccaat cacaatcgct cctaaggtaa
     6361 ttaataagga accaacgatc attggtaaaa taccatagct tgccggaatg ttcgttggcg
     6421 accaatcact gcctaataaa aaacgggcaa agccgtagtt agccatgaaa ggtaagccat
     6481 tactaaaaat aaagaaacag attagcaaaa tagctacaac agctactgtt gcactcatga
     6541 aaaaaattgc cctaaaaact gcttctttga aggcttgttt tatcacatct tgtcctttct
     6601 agtgaagaaa gtaagggaga tacgacacct ccctacttgc cttctttatc ttattgtacg
     6661 atgaaacgtc tgcatctctt tagagattta tggagcaaac attttattta atcttgtccc
     6721 aggtggttaa tttgccacta aaaacgtctg caagttcagc catactgact tggcttgcct
     6781 tattgtcatt attgaccaca acagcaatac cgtctaaagc aatagcatca tgggtgagac
     6841 tcttaccttc ttcaggagtt aattccctag aaaccatacc aatatcagcg gttttctcct
     6901 taacagcggt aatacctgct gaagacccat tagaggtaat atcaatcgta acttctggat
     6961 tttctttttt ataagcttct gctaattttt ccattaaaga agatactgaa gtggaaccta
     7021 caacagacaa cttgcctgat aagtgttggc ttgtatattc tgtggtttcg gttttagctt
     7081 caataaattt attatctgtg accacttgtt gaccttgttt ggagtggata aagctgataa
     7141 aatcttgacc tagcttggaa agattagagg accaaacaat gttgaaggga cgttgaagag
     7201 ggtattcacc atctaaaact gtgtctcgac tagccttgac accatcaatc tctaaagcct
     7261 tgacagattt cgttaaagat cccaaggaga tgtagccgat agcattagca ttcccttgaa
     7321 ctgctgagag aacaccttct gtactatttt gaatcacagc tgttttggca gtgttgtcaa
     7381 tttttttatc accgtctttt ttgagaatcc ctgtgatttc tgtgaaggca ccccgtgttc
     7441 cagagccatt ttctcgtgaa atcacctcaa tcgttcctga agctgactgt ttggaagcag
     7501 ctgactgatt gccacaggca acaagcccaa atcctgataa gccaatggct gcaagagtaa
     7561 gcattttttt gaatttcata ataatcacct ttatctctat gtatttttct tgtgtaggct
     7621 tactacattt atagtctaac aagtctttgt aaaggtttat ccctgattca tgtaaagatt
     7681 gtgtaaagaa tcaaaaaaag ccacttttga aaaatggctg ctcctaaaaa tagctttaaa
     7741 aattattagt cctgtgcgaa agattggtta ggaagaaaaa tcgtgaagca actgcctctg
     7801 ccaagctgac tcgtcaccgt gacttggcca cctaataatt gactgagttc tttgacaatg
     7861 gcaaggccaa gaccagtgcc accagtttgt ctgcttcgac ctttattaac tcggtaaaaa
     7921 cgttcaaaaa tacgatcctg ctctaattga ctaataccaa tccctgtatc tgatacagaa
     7981 atcttaatgc cttcgttcac cttttgggtc ttgacctcaa ttttcccccc ttgttcagtg
     8041 taacggatgg cattggataa aagattgagt aagatttggg aaagtaattg actatctgat
     8101 acgagggtga catcatctgg cacctgcacc tttagctgta aatccttctt cttgagctga
     8161 ggttgcaagc tttgagtcaa atcctgtaca aattctgcca aagaaagggt cgtccattgt
     8221 ataggcattt gttgagcctt agataaggta agaagatgct caacaatatg ctcaagacgc
     8281 aaactttctt tgtaaataat gtctagaaag tcatccttga gcgcttcttc ttcagctgac
     8341 atccccttaa tggtttcagc aaagccctta atcgaagtaa ctggtgtcct caattcatgg
     8401 gaggcatttg agacaaaggc taaatttaac ttttcataag ttctaatcgt tgttaaatca
     8461 tatagcaaga cgagcacagc ttccacagat tgggtggggc taaaaacggg aactgctgtc
     8521 acttctaaaa tcaagtcacc ctcatgaaac ccacttactt cttgttttaa ccttgttttt
     8581 tgatcaaagg cttggtgaac taaatttcga atatccatcc gtttgaggtc atcaagtgaa
     8641 cttatgtcgc cgtccacatc gggaaaataa tgaggcagag agcgactgga taataacatc
     8701 tgaccttgag cggaaactaa aaacgtcccc atggttaggt gcgacagaag aacctccatt
     8761 gtttcggcta ggtccttgta ttgctgatcc tgttgggaga ctttggtttt tagggcagac
     8821 acatactgag ccaaagactt taagtcttct tgcccttttt ctaaaaagta ttcactactg
     8881 gtcaagagag gttggtgcaa ggtctcaaaa gcaacttccc atttccaaag gcaaaagagc
     8941 cagtagccac cttgtcccaa agaaagtgct agaagaaaga gaccgatgcc tttactgatc
     9001 caagttaatg ccatccctgc aatcagaatg aggctaacac ttagattgac tagccaaaat
     9061 tgaaggtagc gtttcatcta taactccttg aacttataac cataaccccg aatggttcga
     9121 ataaattgag gggttttagg attgtcttca attttttccc tcaacttacc aatatgaacg
     9181 tccaccaaac gtgtttcctg cccaaagtca tacccccaga tacgttccaa aagacgctct
     9241 ctagtcagtg tcatgttggg atgtttcata agatagagca agagttcaaa ttcttttggg
     9301 gtcaaactca gtaacttatt cgccttgtag acttcatgac gctcagggta tactttcaag
     9361 gtcccaaata gccaagaatc gtcagcgata ttatctgaat catctccttc ttgttctcct
     9421 ttagttcgcc tgaggacagc cttgacacgc gccagcaatt ctctagggct aaaaggcttg
     9481 gtcaggtagt catcagcccc taattccaag gccaaaacct tatcaaattc atcacttttc
     9541 gcagaaacca tcataattgg agttttgacg cctttggctc tcagccgctt acaaacttcc
     9601 atgccatcta attgtggtaa catgatatca agcaagataa aatcaaaggg ttctgtttct
     9661 gccaaagcta aggccttccg tccatttgtt accaattgag tagaaaagcc ttccttactt
     9721 aaatggtagt caagcaattt cagaatgtgt tcttcatcat ccactaataa gacttgtttt
     9781 gtcatctatt atctcctatt ggtaacatta taacacaatt atcagaaatc ctaacattgc
     9841 taaatcagat taaatttgct tatcaagact agtatctggt caaacgctca atcatctcct
     9901 tgtgctctgg ataggtcgcc agtagatcta ccctttcaaa taattcaaaa tcctcaaatt
     9961 caaaaccagg agcaacaaga caagaaacca gagcatcatc cttatcaact gttgattccc
    10021 aaatagtgcc cttaggaaca cagtagtgaa gttgttgccc tttggatatg tccaggccta
    10081 aagtgactgc ttcgtagtga ccatctgctg taatcatgtg aacagtaagt ggggatcctg
    10141 catgaaaata ccagatttca tctgctgtca atcggtgaaa atgtgaagga ttcgtttctt
    10201 ctaataagaa ataaatactg gtataaagcg cccttccctt accagcaagg tttatagtgt
    10261 ctgaagcttt ttttgtttgt ctaaaatagc cacctttaac atggggagct aactctagag
    10321 ttcttatcaa gtcttcttta tccgtcggag ccaatgggtt gaagtaactc ttgttcaaag
    10381 tggttttacg atttcaagaa ctcctctcag ttctgaggac acggtaatga ttgatgcgac
    10441 ggaagtacaa atcaatcg
//
LOCUS       DAVLGK010000062        10336 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLGK010000062 DAVLGK010000000
VERSION     DAVLGK010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.063"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..170
                     /locus_tag="VXE01_001958"
     CDS             <1..170
                     /locus_tag="VXE01_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0750812.1"
                     /translation="TVSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSGVTLIT
                     GKNGTGKSTLL"
     gene            complement(536..1846)
                     /locus_tag="VXE01_001959"
     CDS             complement(536..1846)
                     /locus_tag="VXE01_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV0750813.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGKTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2083..2955
                     /locus_tag="VXE01_001960"
     CDS             2083..2955
                     /locus_tag="VXE01_001960"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV0750814.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3086..3918
                     /locus_tag="VXE01_001961"
                     /pseudo
     CDS             3086..3918
                     /locus_tag="VXE01_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            3979..4941
                     /locus_tag="VXE01_001962"
     CDS             3979..4941
                     /locus_tag="VXE01_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0750815.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLPHQMETISKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIA
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            5121..6128
                     /gene="gap"
                     /locus_tag="VXE01_001963"
     CDS             5121..6128
                     /gene="gap"
                     /locus_tag="VXE01_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV0750816.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(6197..7033)
                     /locus_tag="VXE01_001964"
     CDS             complement(6197..7033)
                     /locus_tag="VXE01_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0750817.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNFPILGDPLYNSNSKTSRLMLHAFRLSFTHPLTLEKLNFTALSNTFETELKK
                     NG"
     gene            7159..9354
                     /locus_tag="VXE01_001965"
     CDS             7159..9354
                     /locus_tag="VXE01_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0750818.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENISLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            9407..9559
                     /gene="rpmG"
                     /locus_tag="VXE01_001966"
     CDS             9407..9559
                     /gene="rpmG"
                     /locus_tag="VXE01_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0750819.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            9569..9745
                     /gene="secE"
                     /locus_tag="VXE01_001967"
     CDS             9569..9745
                     /gene="secE"
                     /locus_tag="VXE01_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV0750820.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            9800..10336
                     /gene="nusG"
                     /locus_tag="VXE01_001968"
     CDS             9800..10336
                     /gene="nusG"
                     /locus_tag="VXE01_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV0750821.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         3236 a         1800 c         2244 g         3056 t
ORIGIN      
        1 gaactgtttc ttttgctatt agttcaaaag gagaaaaaat gaaagtagaa aatatttcgt
       61 atagggtgga tcatcgtata ttgtttgata atatttcttt tgatacttcg agttcaggcg
      121 tgacattaat tactggtaaa aatggtacag gaaagtcaac tttactatag tagattgaaa
      181 ctagaatagt acacatctac ttctaaaata ttgttagaaa tcgatttgac tatcctgatc
      241 tatttgtcct gttcttattt catttcacta catctcaaat tgagtatgac gaagtgcgct
      301 cccatgtcct gggaacgcac tttcttcata tttttcatat tcttgaatcc atcgataaag
      361 actattggga tgaattttta aagttgaact aatcattttt acaggatgag gtttacagca
      421 gagagtttga aggctttatc aaaggttttt cttggcataa tgacttttcc tcgtttccac
      481 ttaattttgt gtctacttta ttataccaag tccaccctta agttagataa taaatctaac
      541 ttaaggaagc tagaaggatg agaatccagg tggtcaagag tcccaaactt aagctgatgg
      601 ggacacccag aataatttgc tttttgaagg caaggccacg ttcctctata ttgggaagtg
      661 agagttgaat gagagaacca gctgatgaaa agggtgagat attagtagat agagcgccaa
      721 taacggtggc tgttgtgagt aagtgaatat caatctgggg attttgagca ctgatgatag
      781 caatgatggg aaagagggct ggagctacaa cggatagggt ggaactaaag agtgacatca
      841 ctccggctat cacacaaaag aacagaggta accagaaatg aggaatggat gttgtcatga
      901 ggtgccctat cagtgtgact aaacctgact tgaccgctag agacattagt aagctcatgc
      961 cgcagagcat gataattgta gcccagggaa ccttagctaa aatggcttct tgcttcccta
     1021 atttgagcct taaggcgagg cagaccatga gtattgagac aaagccaata tcaaatgttt
     1081 tttgataagt agctatccag gcgatgtttg ggaaaatgag atgcaacaag ggaaaaagcc
     1141 aaaccaaaac catgctgctg atcatgagca aggtggtttg tctttgaacc ttgctgagga
     1201 gtggtggttg gtcaatagtc aaggatgagt ttgtttttcc cttactatag tgactgtaac
     1261 aggataataa aagcaagacg atgagtgggt agataatgct gacgataaag atatgattgc
     1321 caagtgaaaa agcttgctct tcccatccca tttgcttaaa caggccttga aagacaatgc
     1381 ctgagctact ggttatcaaa ttagcccctc ctgaagctcc ccaattgacg gcttgagctc
     1441 caatcaaagg gtgtttgtcc gctttttgac agagggtaat cgctagagga cagcaaacgg
     1501 ccatagtagt gaaaaatcca gcacctaaag cagacaaaag ggttgccatc aggtataaaa
     1561 tcatgtagag ggcgttaggg taggtgcgtg tgcggtagag aatgtgttga gccaaaacat
     1621 caagagtacc gttagttatt gcaaagttat aaaagagaga gacgctaaaa atggtaaaaa
     1681 agagtgaggt tggccaaaaa tgaagaagtt ctttggggct taatcccatg agagtggttg
     1741 cgatgaggta agaaaaagca atagccagca ggccaatatt gattttggtg cggtaaccaa
     1801 ttccaatggc tagagcaatg gcgctaatca ttattaaatg aatcattgaa ttgtcctttc
     1861 agttagaata tggaaatagg ttggcaattt tggcgctcaa aagaccacct gtttcctatt
     1921 ggtacttgac tattatacac aaaaaaaata caattgtctt gacaattgta ttgacacttg
     1981 ttagaattaa aaatgaggta ttcaggcttg tgatttccta tggaagttaa tagtgattgc
     2041 ctctaatgct tacaagtgat attaaaaata gaggacttag tgatgtcaat catttcaact
     2101 gatttaaccc cttttcaaat agatgataca ttgaaagcag ccttgcgaga agatgttcat
     2161 tccgaagatt acagtaccaa tgccattttt gatcatcatg gccaagctaa ggtgtcgctt
     2221 tttgccaagg aagctggtgt tttagcgggg ctaaccgttt ttcaaagggt ttttacccta
     2281 tttgatgccg aggtgacctt ccagaatcct catcaattta aggatgggga tcgtttgact
     2341 agtggcgatt tggttttaga aatcataggc tcggtgagaa gtctcttaac atgtgaacgc
     2401 gttgccttga attttttaca acatttatca gggattgctt cgatgacagc tgcttatgta
     2461 gaagccttag gcgatgattg cattaaggta tttgatactc gaaaaactac tcctaattta
     2521 cgtctttttg agaaatatgc cgtgagagtt ggcggtggct ataatcatcg ctttaattta
     2581 tcagatgcta tcatgctaaa agacaatcac attgcggcag taggtagtgt tcaaaaggca
     2641 attgctcaag cgcgtgccta tgcccctttt gtgaaaatgg tcgaggtgga agtggaaagc
     2701 cttgctgctg ccgaagaagc tgcggcggcg ggtgctgata ttatcatgtt ggataatatg
     2761 tcattggaac agattgaaca ggccattacc ctaattgcag gacgttctcg gattgaatgt
     2821 tctggaaata ttgatatgac cactattagc cgttttcgtg gtttagcgat tgattacgtc
     2881 tccagtggta gtttaaccca tagtgctaag agtcttgatt tttccatgaa ggggttaacc
     2941 taccttgatg tctaagttgt aaaataaact aactttttaa aggatgtctt tcctctagaa
     3001 cgagttttat gtcagatagt ttaaacgcct cttcaaatat agtaaaatga accaaaaata
     3061 gtacacaatg tggtataatc tttttatggc atattcaata gattttcgta aaaaagttct
     3121 ctcttattgt gagcgaacag gtagtataac agaagcgtca cacgttttcc aaatctcacg
     3181 taataccatt tatggctggt taaagctaaa agagaaaaca ggagagctaa accaccaagt
     3241 aaaaggaaca aaaccaagaa aggttgatag agatagactt aaaaactatc ttactgacaa
     3301 tccagacgct tatttgactg aaatagcttc tgaatttggc tgtcatccaa ctaccatcca
     3361 ctatgcgctc aaagctatgg gctacactcg aaaaaaagaa ccacacctac tatgaacaag
     3421 agccagaaaa agtagcctta tttcttaaga attttaatag tttaaagcac ctagcacctg
     3481 tttagattga cgaaacagga tttgatactt atttttatcg agaatatggt cgctctttaa
     3541 aaggtcagtt aagaagaaga tatcagagga tttctttggt tgcaggtcta acaaatgaat
     3601 ggtgagttaa tcgctccaat gacttacgaa gagacgatga cgagcgactt ttttgaagca
     3661 tggtttcaga agtttctctt accaacatta accacaccat cggttattat tatggataat
     3721 gcaagattcc atagaatggg taagttagaa ctcttgtgtg aagagtttgg gcataaactt
     3781 ttacctcttc ctccctactc acctgagtac aatcctattg agaaaacatg ggctcatatc
     3841 aaaaagcacc tcaaaaaggt attaccaagt tgcaatacct tttacgaggc ttttttatcc
     3901 tgctcttgtt tcaattgact atagttcacg gatacagttg ggaaagaagc tattaaatat
     3961 ttggagagtc cttttgggat gaacatgtca aatattacta tagatgggca agaaatggat
     4021 ctgagtcaaa cgatgccttc ttatgctcaa gtagtgagtc tttatgatga tacaagtatc
     4081 tctgttagta ataatgagac ggacaaagtg ttggctggct ccctctatac tgatacaaat
     4141 gaacagggat taacgattcc aagcagttta ctaaaaaatt ggaatgaaca gacaggaaaa
     4201 aatttgacag ctaatgatct tattggcaaa tcagtctcag ccagcattgt agaaagtgct
     4261 gccgaaacta gtaagattgc tcaatttcaa acgaagattg tacgtgtaat caatgatgaa
     4321 gatgacatgg aggacagcaa cagtttcatg ctgcctcatc aaatggaaac gatttcaaaa
     4381 gaggctggat ttacgaaagc tgtatcttat tttatcttgg aactcaaaga tccatcacag
     4441 acaaaagtag taacagaaga attacagaaa aataagaagt atactgtgct ttctcaacag
     4501 agagttcttg atattgtgat tacctttatt cgtgttattc agggattatt gattgtgctt
     4561 tcatcacaag ctattgtggt agcagcggtt atgattggta tcattattta catcaatatc
     4621 atgcaacgtt ccaaggaaat aggtgtcatg aaggcagttg gctatcagaa tcgtgatgtc
     4681 aaaggaattt ttatttacga ggctatctgg attgtaggaa tcgccttgct actggctttt
     4741 ttggtagcac aaggggtggg aagtttagcg aatgcgattg taagtcactt ttacccatcc
     4801 atcgctaagg tctttgaatt aaatttgtta tctgttttag gaactctagt tttcgctctc
     4861 ttgcttggct atgtatcagc ctacttccca gcacgtaaaa ttagtaaaat ggaccctgta
     4921 gaatcgctac gctatgaata gtcaagggtg ttactagatt atcgtcccta aaaaagaaac
     4981 taacagagaa aaacaatgcc cgtacttgca attcaactca aatagttata taataggttt
     5041 gttgaaaggt gatttgtagt gattcaagtt actcttttca caataaaaat ttcatgattt
     5101 tcataaggag gaaatcacta atggtagtta aagttggtat taacggtttc ggacgtatcg
     5161 gtcgtcttgc tttccgtcgt atccaaaacg tagaaggtgt tgaagttaca cgcatcaacg
     5221 accttacaga tccagttatg cttgcacact tgttgaaata cgacacaact caaggtcgtt
     5281 tcgacggtac tgttgaagtt aaagaaggtg gattcgaagt taacggtaaa ttcgttaaag
     5341 tttctgctga acgtgatcca gagcaaatcg actgggctac tgacggtgta gaaatcgttc
     5401 ttgaagctac tggtttcttt gctaagaaag aagcagctga aaaacacctt aaaggtggag
     5461 ctaaaaaagt tgttatcact gctcctggtg gaaacgacgt taaaacagtt gtattcaaca
     5521 ctaaccacga cgttcttgac ggtactgaaa cagttatctc aggtgcttca tgtactacaa
     5581 actgcttggc tccaatggct aaagctcttc aagataactt tggtgttgtt gaaggattga
     5641 tgactactat ccacgcttac actggtgacc aaatgatcct tgacggacca caccgtggtg
     5701 gtgaccttcg ccgtgctcgc gctggtgctg caaacatcgt tcctaactca actggtgctg
     5761 ctaaagctat cggtcttgta atcccagaat tgaacggtaa acttgacgga tctgcacaac
     5821 gcgttccaac tccaactgga tcagttactg aattggtagc agttcttgaa aagaacgtta
     5881 ctgttgatga agtgaacgca gctatgaaag cagcttcaaa cgaatcatac ggttacacag
     5941 aagatccaat cgtatcttca gatatcgtag gtatgtctta cggttcattg tttgacgcaa
     6001 ctcaaactaa agttcttgac gttgacggta aacaattggt taaagttgta tcatggtacg
     6061 acaacgaaat gtcatacact gcacaacttg ttcgtactct tgaatacttc gcaaaaattg
     6121 ctaaataatt cttgaatcga taaaaagcaa ggcctcttgg tcttgctttt cttatatgga
     6181 aaaatggatg acacaatcat ccattctttt ttaattctgt ttcaaaagta tttgagaggg
     6241 cagtgaagtt taatttttct aatgtaagtg gatgggtaaa ggaaagtcga aaggcatgaa
     6301 gcataagccg acttgtcttt gaattgctgt tatagagagg gtcgcccaaa atagggaagt
     6361 tatgatgcga aaggtgcaca cgaatctgat gggttcgccc tgtctttagc ttgcaatgag
     6421 ccaaggaagt cttgtttgag aattgcttta atctgcttac atacgtttca gcatattgcc
     6481 cattttttgc atcaactatt ctttttctac gatcatggcg atcacgtcca attttgtctc
     6541 tgaaaacaag ttcttttctg ttgatatttc catcaactag agcccaatat tctctagaaa
     6601 tctctttttt ctccaataag cgattgagaa tgggcaggat aaaaggattt ttggcaaaga
     6661 gaactaagcc actggtttcc atgtccagac gatgaacgac atagcaggtt tggccaacat
     6721 aggtactgac atggttaaga agggcaattt cgtttggttg attaccatgc gttttcatcc
     6781 cctctggttt gtttacaata atcaagtgtt gatcttgata aacttcctgc actaagtctg
     6841 ggttgcccca agggatcgtc ttttgggaat aatcttcctc gtcaaaagtc aactggcaaa
     6901 catctccagg atttacgatt tcgttccagt ggacttcttc ttgatttatc aaaatatgtt
     6961 tcttgattct caaaaaatga cggatttttc tagggatgag gagttgttcc tcaagtaatt
     7021 gctttaccgt catttgaggt agagaggcgg gtaatgtaaa tgtgaattgc atacagatat
     7081 tgtaacaaaa aaagccctat ttggatagga aatagctaaa ttcttgtctt cctatgatga
     7141 agatgataaa ataaacgcat gaaattagat aaattatttg agaaatttct ttctcttttt
     7201 aaaaaagaaa caagtgaact agaggactct gattctacta tcttacgtcg ctctcgtagt
     7261 gatcgaaaaa aattagccca agtaggtccg attcgaaaat tctggcgtcg ttatcatcta
     7321 acaaagatta tccttatact aggtttgagt gcaggattgc tagttggaat ctatttgttt
     7381 gctgtagcca agtcgaccaa tgtcaatgat ttgcaaaatg ccttgaaaac tcggactctt
     7441 atttttgacc gtgaagaaaa agaggctggt gccttgtctg gtcaaaaggg aacctatgtt
     7501 gagctgactg acatcagtaa aaacttgcag aatgctgtta ttgcgacaga agaccgttct
     7561 ttctataaaa atgacgggat taactatggc cgtttcttct tggctattgt cactgctgga
     7621 cgttcaggtg gtggctctac cattacccaa cagctggcta aaaacgccta tttatcgcag
     7681 gatcaaactg ttgagagaaa agcgaaagaa tttttccttg ccttagaatt aagcaaaaaa
     7741 tatagtaagg agcaaattct aaccatgtac cttaacaacg cttattttgg aaatggtgtg
     7801 tggggtgtag aagatgcgag taagaaatac tttggagttt ctgcatcaga agtgagtctg
     7861 gatcaagctg cgactctggc agggatgctc aaggggccgg aactgtataa tcccttgaat
     7921 tctgtagaag attctactaa tcggcgcgat actgtcttgc agaatatggt tgcagcagga
     7981 tatattgata aaaaccaaga aaccgaagct gctgaagttg atatgacttc gcaattgcac
     8041 gataagtatg aaggaaaaat ctcagattac cgttacccct cttattttga tgcggtggtt
     8101 aatgaagctg tttccaagta taatctaaca gaggaagaga ttgtcaataa tggctaccgc
     8161 atttacacag agctggacca aaactaccaa gcaaatatgc agattgttta tgaaaacata
     8221 tcgctatttc cgagggcaga ggatggaacg tttgctcaat caggaagtgt agctctcgaa
     8281 ccgaaaacag ggggagttcg tggagttgtc ggtcaagttg ctgacaatga taaaactgga
     8341 ttccggaatt tcaactatgc aacccaatca aagcgtagtc ctggttctac aattaagcct
     8401 ttagttgttt atacgccagc agttgaagca ggctgggctt tgaataagca gttggataac
     8461 cataccatgc agtatgacag ctataaggtt gataactatg cagggatcaa aacgagtcga
     8521 gaagttccta tgtatcaagc cttggcagaa tcgcttaatc tacctgctgt tgccactgtt
     8581 aatgatttgg gtgtcgacaa ggcttttgag gcaggcgaaa aattcggact caacatggaa
     8641 aaggtcgacc gtgttcttgg tgtcgccttg ggaagcggtg ttgaaaccaa ccctcttcaa
     8701 atggctcaag catacgctgc ctttgcaaat gaaggtttaa tgcctgaagc tcattttatt
     8761 agtagaattg aaaatgctag tggacaagtt attgcgaatc ataaaaattc acaaaaacgg
     8821 gtgattgata agtctgtagc tgacaagatg accagtatga tgttggggac tttcaccaac
     8881 ggtaccggta ttagttcatc gcctgcagac tatgtcatgg cagggaaaac tggaacaact
     8941 gaagcagttt tcaatccgga gtacacaagt gaccagtggg taattggtta tactccggat
     9001 gtagtgatta gccactggct tggctttccg accactgatg aaaatcacta tctagctggc
     9061 tctacttcaa acggtgcagc tcatgtcttt agaaacattg ccaataccat tttaccttat
     9121 acgccaggaa gtacctttac ggttgaaaat gcttataagc aaaatggaat tgcaccagcc
     9181 aatacaaaaa gacaagtaca aaccaatgat aatagccaga cagatgataa tttgtctgat
     9241 attcgagggc gtgcgcaaag tctagtagat gaggctagcc gggctatctc agatgcgaag
     9301 attaaggaaa aggctcaaac aatatgggat tcgatagtca atctatttcg ctaagatgct
     9361 tgtcaaagcc tagctttctt gttataatgg ataagatgga ggcgttatgg cactaaaaaa
     9421 agcaagccta gcttgtgcgg tttgtggttc gagaaactat tcaatcaaga tcagcggaaa
     9481 ccccaagcct acacgactag aagtaaataa attttgtaag cattgtggca agtacactac
     9541 acacagagaa acgagatagg agagagcgat gcgttttatt ggagatattt ttagacttct
     9601 taaagacaca acatggccaa ctcgcaagga aagctggaga gattttcgtt ctatcatgga
     9661 atacacagct ttctttgtag taattattta catttttgac cagttgattg tttcaggttt
     9721 gattcgattt attaacattt tttagaagat tagtggagtt aattacacta gaaatcttct
     9781 atttatgaaa ggaaatatca tggatagttt tgataaagga tggtttgttt tacaaactta
     9841 ttctggttat gaaaataagg tgaaagaaaa tctattacaa cgtgcacaaa cctacaatat
     9901 gttggataat attctacgcg ttgaaattcc aacacaaaca gtgcaagttg aaaaaaatgg
     9961 aaagagaaaa gaagtagaag aaaatcgctt tccaggttat gttcttgtag aaatggtcat
    10021 gacagatgaa gcttggtttg ttgttcgaaa cacaccaaat gttacaggat ttgtcggatc
    10081 acacgggaac agatcaaaac caactccatt attggaacaa gaaattcgtg acattttggt
    10141 atctatggga caaactgttc aagaatttga tttcgatgtt gagattggtc aaactgtacg
    10201 tattattgat ggtgcttttg cagactacac tggtaagatt acagaaattg ataataacaa
    10261 agtgaaaatg attatctcta tgtttggtaa tgacacagtt gcagaagtaa acctaaacca
    10321 aatcgcagaa ttataa
//
LOCUS       DAVLGK010000063        10037 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLGK010000063 DAVLGK010000000
VERSION     DAVLGK010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10037
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.064"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            203..298
                     /locus_tag="VXE01_001969"
                     /pseudo
     CDS             203..298
                     /locus_tag="VXE01_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(551..1171)
                     /locus_tag="VXE01_001970"
     CDS             complement(551..1171)
                     /locus_tag="VXE01_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0750822.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1171..1653)
                     /locus_tag="VXE01_001971"
     CDS             complement(1171..1653)
                     /locus_tag="VXE01_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV0750823.1"
                     /translation="MAKKVKIKKTLVEQILSKSAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKYLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1653..2495)
                     /locus_tag="VXE01_001972"
     CDS             complement(1653..2495)
                     /locus_tag="VXE01_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV0750824.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2590..3390)
                     /locus_tag="VXE01_001973"
     CDS             complement(2590..3390)
                     /locus_tag="VXE01_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV0750825.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSAQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEKTFRKLFLKP"
     gene            3544..4923
                     /gene="glmU"
                     /locus_tag="VXE01_001974"
     CDS             3544..4923
                     /gene="glmU"
                     /locus_tag="VXE01_001974"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV0750826.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4933..5478
                     /locus_tag="VXE01_001975"
     CDS             4933..5478
                     /locus_tag="VXE01_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0750827.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5490..5804
                     /locus_tag="VXE01_001976"
     CDS             5490..5804
                     /locus_tag="VXE01_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV0750828.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5821..6513
                     /locus_tag="VXE01_001977"
     CDS             5821..6513
                     /locus_tag="VXE01_001977"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV0750829.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6590..7081
                     /gene="rocS"
                     /locus_tag="VXE01_001978"
     CDS             6590..7081
                     /gene="rocS"
                     /locus_tag="VXE01_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV0750830.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7179..7769
                     /locus_tag="VXE01_001979"
     CDS             7179..7769
                     /locus_tag="VXE01_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV0750831.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7778..9541
                     /locus_tag="VXE01_001980"
     CDS             7778..9541
                     /locus_tag="VXE01_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV0750832.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            9755..>10037
                     /locus_tag="VXE01_001981"
     CDS             9755..>10037
                     /locus_tag="VXE01_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0750833.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKKK
                     TGELNHQVKGTKPRKVDRDRLKNYLTDNPDAYLTEIASEFGCHPTTIHYA"
BASE COUNT         3133 a         1737 c         2123 g         3044 t
ORIGIN      
        1 ttttataatt ttaaagactt tttgactagc ctcatttttt taacttgata ctcagtgaaa
       61 agcaaagatt aaactaggaa gctagctgta ggctgctcaa agaacagctt tgaggttgca
      121 gataaaactt gtgaggtaac caacatatat aatgtgaagc tgacgtggtt tgaatagatt
      181 ttagaagggt atgagtctgg aagttttaat ggataatgca agattccata gaatgggtaa
      241 gctagagttc ttatgtgaag agtttgggca taaactttta ccttttcctc cctactcatc
      301 ttagtataga aaagtgaatc taaaatagta cataactgct tctaaaacat tcttataaat
      361 tgatttaaat tctcaaatca tattattcag ttcttatttc attttgctct acaatcctgt
      421 tgagaagaca cgtgttcata tcaaaaaggt attggcaagt tgcaatacct ttttacaagg
      481 ttcttttgtc ttatttttgt ttcaactgac tatatctcct atggttctag ttcagaaggc
      541 taggctataa ttatgattga taagaagtat cattccaagt attgagagtg aatgtttcaa
      601 aatcatgggt ttctataatg gtcaggctgg catttgctag accgccatct ttacgaagaa
      661 gtggttcttt atagcctagg agagtacgaa gactggcagt aagattggcg ccgtgtccga
      721 caattagaat acgctcagct ggactatctt ttaatgattt gataaattgg atggtccgct
      781 gagttgtact atagagggat tcggctccga acattcgagt gtcaaattga gcaagatttg
      841 aacgaaaagc ctggatttgt tgcgggtaaa tagcttccag ggttgcaatt ttcaaacctt
      901 ctaacttccc aagttgccat tcacggagat taggaacgat ttctaaagaa cagggggtat
      961 ggagttgact ttggataatc tcagcagatt tgaccgctcg aggtaaatca cttgaataaa
     1021 tctgatcaaa aggaatttcc ttgagatact gaccaagtcg ttttagggtt tcaatggatt
     1081 caggaagaag aggagaatca ccactagcac cttgaaaacg accttcttgg ttccagaggg
     1141 tacgaccgtg gcggacaaag tagagtttca ttacttgatg tcctccaaaa tatctacaaa
     1201 gtctgccttt acaaagctag ccaagtcttg tggcgcgacg ataatgctgt gtccgacttc
     1261 gcctgcagag acaatcattt gatccaaatc tagagcaatt ttatcgataa aaatgggata
     1321 attgtgtttc tgacgaattc cgacaggatt attggctcca tgaatgtaac cagttgtttt
     1381 ttctaagtac ttttgtggaa tcatgctcac ttttttattg ccagaaattt tagctagttt
     1441 cttttcagac aagtgctgag tgatagggac aattccgata atcggtccgg tcttgtctcc
     1501 caaaagcgcc aaggttttga aaatctgatc tcgttcataa ccttgaggaa gctctccttc
     1561 tagggcattg atttgaatcc cctgatgagg gatagctgat ttagatagga tttgttctac
     1621 caatgttttt ttgattttaa ctttttttgc cattatttat atttatcctc caattgactc
     1681 atccaaatac caagccagat tcccagcgca aagaagaagg cgatgatgac ataaccgaca
     1741 agtgaaagtc ctgtgtattg gatactttca gcgtttcctg catttggaat taagatcaaa
     1801 agggtacttg ataggacgat accgatgatg aaatgataga cgcgtgagtg gtagttgttt
     1861 aaggcataat ccatcaattt tgaaaaaacg atgagagttg cacctgcacc aattccaatc
     1921 ggaaagaagg ttcccaagag atcaaaagtt ttaaaaccag tcaacatagg agcatagagt
     1981 cccaaaatca aaagtaaatt cgatgggctg aggccaggaa ccaagacgcc aagggccaat
     2041 agtgcgcctg ctaggacgaa gttaagaaag ctggcgctta aggttccaac gacaaaattt
     2101 aaggcataga gtcctaatcc agaaatgata aaggttgtcc ataaccaagc taaatcaatc
     2161 ttgtctcggt cagattctcg agttgattct ttgaggaggc taggaactgt accgataata
     2221 gctcccgcaa agctccataa tacaaagacc tgataatttt caagtaggta ttcaatcggg
     2281 taggaaaata agccgattcc tagaagcata ccgatggcaa ctggaataaa gtacaaaaca
     2341 ttttctttaa ggtctttaaa gggatgggcc agaaagccaa tcattcgttc atagattcct
     2401 aagattgctg ctagaacccc tccggaaatt cccggtagga taaatccaag agcaattaca
     2461 atccctttaa taacgcgtgc taaccatgag agcatatatt tcctccaact atttctattt
     2521 caaaaaatcc ttactatatt gtatcacaat cagacacaaa aagaaaaagc aaatgataaa
     2581 caaatgcttt taaggtttta aaaaaagctt tcgaaaggtt ttttctttat tttttaaggg
     2641 agagataacg ttgatatcta aatcgtggtc aaagccagca atttttcctt tagatgtgta
     2701 ttggtgaata tcataatcta aatcagtttt aggactgctc tccaaaaatc ctgagtctga
     2761 gccgtaggac ggaatccaaa cagaggtaaa cttgcctgta tcaatactgt gttcttccat
     2821 gaagtagaca ccaacgtaga tgccgatgtt tttagcacct agtgatgcta gttttgctcg
     2881 aaagttttcg acaccttcgt tcatattaga catggttttg tcttccacgt caagccaata
     2941 gtaactaggg ctgtaaggag aggcagcatt gtagaaaact tcggcagcct tttccatttc
     3001 ttgggcactt tttccagcta cataagcgta gacagcaact gggacattcc gcttttgaag
     3061 ttcagtgata tgactcttat aggccttgtc tattccattg ataaatgaag catcattttc
     3121 ttttgtcgtt tgagcaccac tgtgaacacg aacaatagca cctgaaatat tttgtgagag
     3181 ggcatcgtag ttgatttcct caggacgctg ccagccagag aggtcaataa tcggtttgtc
     3241 taagtgtttc aaagcctgtg cttcaatctg tgctatattg gattttgttt taaacgattg
     3301 gttgtcatta agtgggcgat tgatgattaa aatgaacatc ataatcccca aaaaactaaa
     3361 taaaataagt ggatgaattt gttttctcat atcttataat tctaccctaa aaatcaaaaa
     3421 aaatcaaaaa aaatcaaaaa aatgggttaa ggaagagact ttagagcatt ttttcattca
     3481 agagtgcgga atgatttgaa atatggtata ataaaaggga atttctacag aaaagagaag
     3541 attatgtcaa attttgccat tattttagca gcgggtaaag ggactcgcat gaaatctgat
     3601 ttgccaaaag ttttgcacaa ggttgcgggt atttctatgt tggaacatgt tttccgtagt
     3661 gtgggagcta tccaacctga aaagacagta acagttgtag gacacaaggc agaattggtt
     3721 gaggaggtct tggctggaca gacagaattt gtgactcaat ctgaacagtt gggaactggt
     3781 catgcagtta tgatgacaga gcctatctta gaaggtttgt caggacacac cttggtcatt
     3841 gcaggagata ctcctttaat cactggtgaa agcttgaaaa acttgattga tttccatatc
     3901 aatcataaaa atgtggccac tatcttgact gctgaaacgg ataatccttt tggctatgga
     3961 cgaattgttc gtaatgacaa tgctgaggtt cttcgtattg ttgagcagaa ggatgctaca
     4021 gattttgaaa agcaaatcaa ggaaatcaac actggaacat acgtctttga caacgagcgt
     4081 ttgtttgagg ctttgaaaaa tatcaatacc aataacgctc aaggcgaata ctatattaca
     4141 gacgtcattg gtattttccg tgaaactggt gaaaaagttg gcgcttatac tttgaaagat
     4201 tttgatgaaa gtcttggggt aaatgaccgt gtggcgcttg cgacagctga gtcagttatg
     4261 cgtcgtcgca tcaatcataa acacatggtc aacggtgtta gctttgtcaa tccagaagca
     4321 acttatatcg atattgatgt tgagattgct tcggaagttc aaatcgaagc caatgttacc
     4381 ttgaaagggc aaacgaaaat tggtgctgag actgttttga caaacggtac ttatgtagtg
     4441 gacagcacta tcggagcagg agcggtcatt accaattcta tgattgagga aagtagtgtt
     4501 gcagacggtg tgacagtcgg tccttatgct cacattcgtc caaattcaag tctgggtgcc
     4561 caagttcata ttggtaactt tgttgaggtg aaaggatctt caatcggtga gaataccaag
     4621 gctggtcatt tgacttatat cggaaactgt gaagtgggaa gcaacgttaa tttcggtgct
     4681 ggaactatta cagtcaacta tgacggcaaa aacaaataca agacagtcat tggagacaat
     4741 gtctttgttg gttcaaattc aaccattatt gcaccagtag aacttggtga caattccctc
     4801 gttggtgctg gttcaactat tactaaagac gtgccagcag atgctattgc tattggtcgc
     4861 ggtcgtcaga tcaataaaga cgaatatgca acacgtcttc ctcatcatcc taagaaccag
     4921 taggagccta tcatggagtt tgaagaaaaa acgcttagcc gaaaagaaat ctatcaagga
     4981 ccaatattta aactggtcca agatcaggtt gaattaccag aaggcaaggg aactgcccaa
     5041 cgggatttga ttttccacaa tggggctgtc tgtgttttag cagtaacgga tgaacaaaaa
     5101 cttatcttgg tcaagcagta ccgcaaagct atcgaggctg tctcttacga aattccagcc
     5161 ggaaaattgg aagtaggaga aaacacagcc cctgtggcag ctgcccttcg tgaattagag
     5221 gaagaaacag cctatacagg gaaattagaa ctcttgtacg atttttattc agctattggc
     5281 ttttgtaatg agaagttaaa actatattta gcaagcgatt tgacaaaagt ggaaaatccg
     5341 cgtccgcagg atgaggatga aaccttggaa gtccttgaag tgagcttaga agaagcgaaa
     5401 gaattaatcc aatcaggtca tatttgtgat gccaagacaa ttatggctgt tcagtattgg
     5461 gagttgcaga aaaaatagag gaggtcagta tgggtaaatc tttattaacg gatgaaatga
     5521 ttgaaagagc taatagaggc gaaaaaattt caggtcctcc tttgctagat gataatgagg
     5581 aaactaagat tttaccaacc tcttcttccc gttttggtta tgccaatcct aaggatcatg
     5641 gttttagcca ggaaaccttg aagattcagg tcgaaccatc tattcataaa agccgtcgta
     5701 ttgaaaatac caagagaaat gtcttcaatt ctaagttgaa taaaatctta tttgcggtca
     5761 tctttctctt gattttgctt gttttagcaa tgaaactttt gtaatagaaa aggaattgaa
     5821 atgaaaatag gaattattgc tgctatgcca gaagaactgg cttatctggt ccagcattta
     5881 gataatgccc aggagcaagt tgttttgggg aatacctatc atacaggaac cattgcttct
     5941 catgaagtcg ttcttgtaga aagtggaatt ggtaaggtca tgtctgctat gagtgtggcg
     6001 attttggctg atcatttcca ggtggatgcc cttattaata cgggttcagc tggggcagta
     6061 gcagaaggta tcgctgttgg ggatgtcgtg attgctgaca aattagccta tcatgacgtg
     6121 gatgtcacag cttttggcta tgcttatgga caaatggcgc aacaaccgct ttatttcgaa
     6181 tcagacaaaa cctttgttgc tcaaatccaa gagagtttat ctcaattgga ccaaaactgg
     6241 catcttggtt tgattgctac aggagatagt tttgttgcag gaaatgacaa gatagaagcg
     6301 attaagtccc atttcccaga agttttagcc gtggagatgg agggggcagc tattgctcaa
     6361 gcagcgcatg ccctcaatct cccagtctta gtcatcagag ctatgagtga caatgccaac
     6421 catgaagcaa acatcttttt tgatgagttt attatcgaag ctggacgtcg ctctgcccaa
     6481 gtcttgttga cctttttgaa ggctttagat taagcggaaa tttgacagtt tttctagctt
     6541 atgataagat ttaagtaaag aaaagctaga aaacgtttca gaggatatta tgagtattga
     6601 aatgaccgtc agtgagattg cagaggtctt aggattatct cgccaagcaa tcaataaccg
     6661 tgtcaaagaa ttaccagaag aagacacaga taaaaatgac aaaggggtaa cagttgttac
     6721 cagaagtggc ttgattaagc tagaagaaat ctataaaaaa acgatttttg aagatgagcc
     6781 tgtcagtgaa gatgtcaaac aacgtgaact gatggagatt ctagtggatg agaagaatgc
     6841 agaaattctt cgtctttatg aacaattaaa agccaaggat cgtcagttat cagaaaaaga
     6901 cgagcagatg cgtatcaaag accgtcagat tgctgagaaa gacaaacaat tagatcagca
     6961 acaacaattg acccttcaag ccatgaagga tcaagaaaat cttaagctag agctggacca
     7021 agcaaaagaa gaagtccaat ccactaagaa aggctttttt gctcgtttat ttggaggata
     7081 atcaaggagc tgtttaggtt aaatgctaac ctgatggctt cttttgtttg tgaatagtat
     7141 agttgattag aacagagaca gtagaggaga ggtacagaat ggaacgatta gaagattaca
     7201 ttgcttttga tttagaattt aatcagcacg aaggacaaac acacttgatt caagtatcgg
     7261 cagtgcgttt tagagatggt cgggaaatcg atgcctatga ttcctatgtt cataccagcg
     7321 tccctctaaa aagctttatc aatggtttga ccgggattac agctgagacc ttaaaagatg
     7381 ctcctccagt tgagaaagtc ttagaagaat tccaagagtt tgtgggttct ttgctgatga
     7441 taggctacaa tgctgctaaa agtgatttac ctattttagc agagcatggt ttagactata
     7501 gccaacagta caaggtggat ttgtatgatg aagcttttga acgtcggagt tcagatttac
     7561 atggtattgc caatctcaaa ttgcaaactg ttgcctcatt tcttggattt caaggtcagt
     7621 ctcataatag tttagaggat gctcggatga cggcgcgtgt ttacgaatcc ttcttagagt
     7681 cggatcaagc tagggaattg ttagagacag aaagtagctt atcaaacaat ccttttggtg
     7741 gcttggactt gtctcaatta tttgactagg agtgcctatg aaacctgaaa aacctaaaaa
     7801 attgggtctt aaacagattt acctcaatct tgataaaatc ctctttctat ttttcttgat
     7861 ttttatgata gtggagtatt tgtgggtacc attcaattca tggttggcta gcttcttatt
     7921 agatcagaca ggttatcttt ttatttccta taacaatgtc ttagccatcc ttactcattc
     7981 tccattgatt agtctagctt ttttagcctt gattgtaatt aaccttctgg ttgcttattt
     8041 tcaaatagga ctcctcttta ttggtgctcg tcatctcctc tataatgaaa agcgaaggct
     8101 aattgagtat atccgcaagg ttttccatga aagttttgga tttatgaaaa agctaacttg
     8161 cgctaaagcc ttgtttatct ttttctatat agctatgctt tttcctttta tacggaaaat
     8221 gttgaagatt tattatctta ataaaatcgt cattccagag tttatccaag cttatttaga
     8281 agataaatat tggatgtggt ggctgagcat cctacttcta tctcttatct ttctctatgt
     8341 ctctgtcaga ttgatgtttg cccttccgaa gattgtatat gatcagctga ctgttcgaga
     8401 agcagtgatg tttagcttgg agaaaaccaa gaagagagtt actttttatg cttggaattt
     8461 attttacatc ttgctcaaag cacatttatt attttatctt cctttgatcc ctttattatt
     8521 ggctcaaact ttggtagatg atatcactca gagagagtct ctgattcttg gtattttgaa
     8581 ttttgtcgtg attaaaaatc tctattatat ggctctgact tattttttgg ttaaatttgt
     8641 ttcatttttg acaggaaagg agctggatat gcttcctagg agagaaaaag atcacatcgt
     8701 gcgatggggt gtcatgactt gtgccagtct tttctttgcc ttagaaggtt atatttatct
     8761 ggaggctccc atggttcatc tacctcaact tatttctcac cgaggggttt ccaatgcaaa
     8821 tgggattcaa aatacagtag agtccttgga aactacagca caactcaaac cagacttggt
     8881 ggagacggac gtgcaggaaa caaaagatgg gcagtttgtc atgatgcatg atgctaactt
     8941 gaaaaatcta gcaggtatca ataaaagtcc tcaagactta aacttggagg agcttaaagg
     9001 gattgatatt tttgaaaatg gctaccagac taaaatttca agctttgaag attatctcag
     9061 tcgagccaac gaacttggtc aaaaattact aattgaaatt aaaaccagta aaaaagatag
     9121 tccagacatg atgaaccgct ttttagcccg ttatgctgca aagctcaaga tttatggaca
     9181 tcaaatccag tctttagact accatgttgt cgaaaaagta agacagtatg atgccgaact
     9241 gccagtttat ttcatcatgc cctacaattc tgtctttcct aaaacaagag cgacaggata
     9301 tactatggag tactcaacct tggatgaata ttttgtaagc aaactatgga caacggatca
     9361 gaaactttat gtctggactg tcaatgattc agaagctatc agcaaatctc ttcacttagg
     9421 agtagatgga gtgattacag atgatttgga aaaagttcag cgggaaatag aagtagccca
     9481 agaagatcca gaatatacgg atttgctctt gaaaaaagca ttggaattct ttgaatttta
     9541 gtaataaaaa agaggaacgg ttgttcctcc catgataggt aagtattctt gtgaatgctt
     9601 gcttttttgt ggttgcaatc cgtttacgag aattgtttgt attgttcttg tttcaattta
     9661 ctttatagtg ctttgaagtt ggaatgctac actataactt ataaaatata gtaaaatgaa
     9721 ccaaaaatag tacacaatgt ggtataatct tcttatggca tattcaatag attttcgtaa
     9781 aaaagttctc tcttattgtg agcgaacagg tagtataaca gaagcatcac acgttttcca
     9841 aatctcacgt aataccattt atggctggtt aaagctaaaa aagaaaacag gagagctaaa
     9901 ccaccaagta aaaggaacaa aaccaagaaa agttgataga gatagactta aaaactatct
     9961 tactgacaat ccagacgctt atttgactga aatagcttct gaatttggct gtcatccaac
    10021 taccatccac tatgcgc
//
LOCUS       DAVLGK010000064         9978 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLGK010000064 DAVLGK010000000
VERSION     DAVLGK010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9978
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.065"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            71..1468
                     /locus_tag="VXE01_001982"
     CDS             71..1468
                     /locus_tag="VXE01_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEV0750834.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEAFRHGNRNRKPKHAIPDEIKERILKKYLSYETYKPNVLHFCELLAEEEGIKLSDT
                     TVRKILYKKNILSPKSHRKTKKRVRKQAKLNLNQPLDNPILPTAKDFLEDPKKVHPSR
                     PRKKFSGELIQMDASPHAWFGPETTNLHLAIDDASGNILGAYFDKQETLNAYYHVLEQ
                     ILANHGIPLQMKTDKRTVFTYQASNSKKMEDDTYTQFGYACHQLGILLETTSIPQAKG
                     RVERLNQTLQSRLPIELERNNIHTLEDANTFLLSYIQTFNEQFGNKTKLSVFEEAPNP
                     SERNLILARLAERVVDSGHHIRFQNRYYMPVEQGKEVYFIRKTKALVLKAFDGDIYLN
                     IADKIYHTKELLDHELYSKNFEQEPEQKKERRKYIPPQTHPWKLTSFKQYLHKNKKDY
                     EEFTSEELHSPQLQV"
     gene            complement(1756..1932)
                     /locus_tag="VXE01_001983"
     CDS             complement(1756..1932)
                     /locus_tag="VXE01_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0750835.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(2043..2240)
                     /locus_tag="VXE01_001984"
     CDS             complement(2043..2240)
                     /locus_tag="VXE01_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0750836.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(2495..4039)
                     /locus_tag="VXE01_001985"
     CDS             complement(2495..4039)
                     /locus_tag="VXE01_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV0750837.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            4252..4554
                     /gene="gatC"
                     /locus_tag="VXE01_001986"
     CDS             4252..4554
                     /gene="gatC"
                     /locus_tag="VXE01_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV0750838.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            4554..6020
                     /gene="gatA"
                     /locus_tag="VXE01_001987"
     CDS             4554..6020
                     /gene="gatA"
                     /locus_tag="VXE01_001987"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV0750839.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLEDIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            6020..7462
                     /gene="gatB"
                     /locus_tag="VXE01_001988"
     CDS             6020..7462
                     /gene="gatB"
                     /locus_tag="VXE01_001988"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV0750840.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            7591..8151
                     /gene="efp"
                     /locus_tag="VXE01_001989"
     CDS             7591..8151
                     /gene="efp"
                     /locus_tag="VXE01_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV0750841.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            8173..8562
                     /locus_tag="VXE01_001990"
     CDS             8173..8562
                     /locus_tag="VXE01_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0750842.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            8555..8977
                     /gene="nusB"
                     /locus_tag="VXE01_001991"
     CDS             8555..8977
                     /gene="nusB"
                     /locus_tag="VXE01_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV0750843.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREYT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAINEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(9027..9404)
                     /locus_tag="VXE01_001992"
     CDS             complement(9027..9404)
                     /locus_tag="VXE01_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0750844.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(9767..9952)
                     /gene="briC"
                     /locus_tag="VXE01_001993"
     CDS             complement(9767..9952)
                     /gene="briC"
                     /locus_tag="VXE01_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV0750845.1"
                     /translation="MTATETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
BASE COUNT         3125 a         2254 c         1889 g         2710 t
ORIGIN      
        1 gtctttagta aatcgaacgt gaaaatgtca catttggtag aatagtcata tgaaaaggat
       61 ccaactgaat atgaatgaaa cgaaaaaata tcttgtgata aaagctatag cccaaggaaa
      121 gaaaacaaag aaacgggcct gtgtcgaact caatctttct gaaagacaaa tcaatcgtct
      181 gctactagcc tatcaacaga aaggaaaaga agctttcaga cacggaaaca gaaatcgaaa
      241 accaaaacat gcaatccctg atgaaatcaa agaacgtatc ctaaagaaat acctctccta
      301 tgaaacatat aaaccaaatg tccttcattt ctgtgaatta ctagctgaag aagagggaat
      361 taagctctct gatacaactg ttagaaaaat actctataag aaaaacatcc tttctcctaa
      421 gtctcacaga aagacaaaga agagagtaag aaaacaagct aaactgaacc tgaatcaacc
      481 cctagacaat ccaatcttac cgacggctaa agacttcctg gaagacccta aaaaggtaca
      541 tcctagtaga cccagaaaga aattttctgg agaactcatt caaatggatg ccagccctca
      601 tgcctggttt ggaccagaaa ccaccaactt acacttagcc attgatgatg cttctggcaa
      661 tatcctaggc gcttattttg acaaacaaga gaccttgaat gcctactacc atgtcctcga
      721 acaaatctta gccaatcacg gcattcccct tcaaatgaaa actgataaga gaacggtctt
      781 tacctatcag gcctccaact ctaagaaaat ggaggacgac acctatacac aatttggata
      841 cgcctgtcac caactaggga ttctccttga gaccacctct atccctcaag ctaaagggag
      901 agtcgaaaga ctcaatcaga cactacaatc acgcctgcct atcgaactgg aacgaaacaa
      961 tattcataca ttggaagatg ccaatacttt ccttctttcc tacatccaaa cctttaatga
     1021 acagtttgga aacaagacaa aactctctgt ttttgaggag gctcctaacc cctctgaacg
     1081 gaatctcatt ctagctagac tggcggagag agtcgtcgat agtggacacc atatccgatt
     1141 ccaaaatcgt tactatatgc ctgttgaaca aggaaaagaa gtctatttca tcagaaagac
     1201 gaaagcatta gttctaaaag catttgatgg tgacatctac ctcaatatcg ctgacaaaat
     1261 ctatcacaca aaggagctac tagatcatga actctattcg aaaaactttg aacaagaacc
     1321 agaacaaaaa aaagaaagac gcaagtatat ccctccacaa acccatccgt ggaaactcac
     1381 atctttcaaa caataccttc ataaaaataa aaaggattat gaagagttta ctagtgagga
     1441 gcttcattct cctcaactac aagtataatc tatttttcgc taaatgggaa gcttttcctt
     1501 aaagaaaacc actctatccc ttacatttag gagagggaaa gtgaggagtg taagacaagc
     1561 atttcatttg ataagaggct tggagctgtt aggctggcga gccaaggcta agactagcct
     1621 tggtttagct aacaaaacag cttcaagggc tcctcgtgtc aaatgaaatc aaaataattg
     1681 ccctcaaact ctccattttt tggggacata atcactttcg attgacaggg aattggaaga
     1741 ttttttattt gtgtcttaaa tcaggtcttg cgtgacattt tctgctctcc acatgccatc
     1801 gttgattaac agaacaccag aattaaaatt atgtgtataa aaatcatctc taactgcagc
     1861 taagggtata gccgtcaagt ccaaatccca cagctcatct atcgattttc ttacaacaat
     1921 atctgaatcc aaatacagta cacgagactc gcttacatac tttggaataa aatacctaaa
     1981 aaagccgcat atgaaagtcc ctcaaagggg agacgataac ctttcagaat attactgtca
     2041 atctaaacat tcacaatctc actattcaaa gtctctagtc ttttttccat caattggaac
     2101 cattctcgcg gaaggtcatc attaaaaaca taaaacttaa gattataatg atgaacacaa
     2161 agagatttta ttgttgtttc aactttatcc atataagcat tatctgcacc taagacaatc
     2221 gcttttttct cttctttcac tttttatctc atttcttttt attcccatca tatgtttcta
     2281 cgtaaccatt attttcgcct attcgttcgt aaaaccatac cagtggagat tttagatgaa
     2341 gtcccattac ggtttacaat ttttacatta cgacacggag ttttacaaat cgatttcatt
     2401 tgccaaacgt agttagtgag gcagttagct agttcgccaa atagcgacta gcgtccaaca
     2461 atttggaact ttagttccaa ttgttggtac tgagtcacat cttctcctct aactctacgt
     2521 ctggatactt gtccgcaaac cagcggaggg caaagtcatt ttcaaagaga aagactggtt
     2581 ggtcaaaacg gtctttggct aagatattgc gacttgacga catccgttca tccaagtcct
     2641 caggcttgat ccaacgaacg gtctttttac ccattgggct catgaccact tccgcattgt
     2701 attcgccttc catacggtgt ttaaagactt caaactggag ttgaccaaca gctcccagca
     2761 tgtactcacc tgtttggtaa ttcttataaa gctgaacggc tccttcttgc accaattgct
     2821 caatcccctt gtggaaggat ttttgcttca taacattctt agcagaaact ttcatgaaaa
     2881 tttcaggagt aaaggttggc agtggttcaa attcaaactt gttttttcca accgtcaagg
     2941 tatccccaac ctgataagta ccggtatcgt aaaccccgat aatatcacct gccacggcat
     3001 tggtcacatt ctcacgactc tccgccataa actgggtaac attagatagt ttagccccct
     3061 taccagtacg agggagattg acactcatgc cgcgctcaaa ttcgcctgat acgatacgga
     3121 caaaggcaat acggtcacgg tgacgaggat ccatgttggc ttggatttta aagacaaagc
     3181 ctgagaaatc cttgtcataa ggatccacaa tttcaccgtc tgttttcttg tgaccatgtg
     3241 gttctggagc aaacttgagg aagatttcaa ggaaggtctg cacaccaaag tttgtcaggg
     3301 ctgaaccgaa aaagacaggc gtcaattctc cagccagaat agcttcctct gaaaactcat
     3361 tcccagcttc atttaaaagc tcaatgtcat ccttgacttg ctcgtagaaa ggattgctac
     3421 caaagagttt gtccccgtct tctagactgg caaaacgctc atccccttta taaagctcta
     3481 aacgttggtt atagaggtca tacaagccct caaaggcttt ccccatcccg ataggccagt
     3541 tcatagggta gctagcaatg cccaagattt cttccaattc ttgcaagaga tccaaaggct
     3601 cacgaccgtc acggtccagc ttgttcataa aggtaaagac tggaatgcca cgatgtttca
     3661 caacctcaaa caatttcttg gtttgagcct cgatcccctt ggcagagtcc acgaccatga
     3721 ccgcagcatc caccgccatc aaggtacgat aggtatcttc tgagaagtcc tcgtgccctg
     3781 gcgtgtctaa gatattcacg cgcttgccgt cgtagtcaaa ttgcataaca gatgaagtaa
     3841 cagaaatccc acgttgcttc tcgatatcca tccagtcaga tttagcaaaa gtccctgttt
     3901 tcttcccttt taccgtacca gcctcacgaa tctcaccccc aaagtagagt aactgctcag
     3961 tgatggttgt tttccccgcg tccgggtggg agataatggc aaaggtacga cgtttcttaa
     4021 tttcttcttg aatattcata agttctcttt ctttgattct ctatttttct tgtttcaata
     4081 gctgagaatg atttttacat tggattttac cattcctttc aacactccat tatatcggat
     4141 tttagcattt ttttcaattt ctatttcttt tcacttcccc ctcccttatt tatgggaaaa
     4201 tatggtaaaa tagaacagac taaaaatcat catttcacga aaggatgcaa gatgaaaatt
     4261 acgcaagaag aggtaacaca cgttgccaat ctttcaaaat taagattctc tgaagaagaa
     4321 actgctgcct ttgcgaccac cttgtctaag attgttgaca tggttgaatt gctgggcgaa
     4381 gttgacacaa ctggtgtcgc acctactacg actatggctg accgcaagac tgtactccgc
     4441 cctgatgtgg ccgaagaagg aacagaccgt gatcgcttgt ttaaaaacgt acctgaaaaa
     4501 gacaactact atatcaaggt gccagctatc ctagacgatg gaggagatgc ctaatgactt
     4561 ttaacaataa aactattgaa gagttgcaca atctccttgt ttctaaggaa atttctgcaa
     4621 cagaattgac ccaagcaaca cttgaagata tcaagtctcg tgaggaagcc ctcaattcat
     4681 ttgtcaccat cgctgaggag caagctcttg ttcaagctaa agccattgat gaagctggaa
     4741 ttgatgctga caatgtcctt tcaggaattc cacttgctgt taaggataac atctctacag
     4801 acggtattct cacaactgct gcctcaaaaa tgctctacaa ctatgagcca atctttgatg
     4861 cgacagctgt tgccaatgca aaaaccaagg gcatgattgt cgttggaaag accaacatgg
     4921 acgaatttgc tatgggtggt tcaggtgaaa cttcacacta cggagcaact aaaaacgctt
     4981 gggaccacag caaggttcct ggtgggtcat caagtggttc tgccgcagct gtagcctcag
     5041 gacaagttcg cttgtcactt ggttctgata ctggtggttc catccgccaa cctgctgcct
     5101 tcaacggaat cgttggtctc aaaccaacct acggaacagt ttcacgtttc ggtctcattg
     5161 cctttggtag ctcattagac cagattggac cttttgctcc tactgttaag gaaaacgccc
     5221 tcttgctcaa cgctattgcc agcgaagatg ctaaagactc tacttctgct cctgtccgca
     5281 tcgccgactt tacttcaaaa atcggccaag acatcaaggg catgaaaatt gctttgccta
     5341 aggaatacct cggtgaagga attaacccag aggttaagga aaccattcta aatgccgcta
     5401 aacactttga aaaattgggt gctatcgtcg aagaagtcag ccttcctcac tctaaatacg
     5461 gtgttgccgt ttattacatc atcgcttcat cagaagcttc atcaaacttg caacgttttg
     5521 acggtatccg ttacggctac cgcgcagaag atgcgactaa tcttgatgaa atctatgtaa
     5581 acagccgtag ccaaggtttt ggtgaagaag tgaagcgccg tatcatgctg ggtactttca
     5641 gtctttcatc aggttactac gatgcctact acaagaaggc tggacaggtc cgtacactta
     5701 tcattcaaga tttcgaaaaa gtcttcgcgg attacgattt gattttgggt ccaactgctc
     5761 caagtgttgc ctatgacttg gattctctca accatgaccc agttgccatg tacttagccg
     5821 acctcttgac catacctgta aacttggcag gactgcctgg aatttcgatt cctgctggat
     5881 tctctcaagg tctacctgtc ggactccaat tgattggtcc caagtactct gaggaaacca
     5941 tttaccaagc tgctgctgct tttgaagcaa caacagacta ccacaaacaa caacccgtga
     6001 tttttggagg tgacaactaa tgaactttga aacagtcatc ggacttgaag tccacgtaga
     6061 gctcaacacc aattcaaaaa tcttctcacc tacttctgcc cactttggaa atgaccaaaa
     6121 tgccaacact aacgtgattg actggtcttt cccaggagtt ctaccagttc tcaataaagg
     6181 ggttgttgat gccggtatca aggctgctct tgccctcaac atggacctcc acaaaaaaat
     6241 gcactttgac cgcaagaact acttctaccc tgataatccc aaagcctacc aaatttctca
     6301 gtttgatgag ccaatcggtt ataacggctg gattgaagtc gagctagaag acggtacgac
     6361 caagaaaatc ggtatcgaac gtgcccacct agaggaagac gctggtaaaa acacccacgg
     6421 tacagacggc tactcttacg ttgaccttaa ccgccaaggg gtacctttga ttgagattgt
     6481 atctgaagcc gatatgcgtt cgccagagga ggcctatgct tatctgacag ccctcaagga
     6541 agttatccag tacgctggca tttctgacgt taagatggaa gaaggttcta tgcgtgtgga
     6601 tgccaacatc tcccttcgcc cttatggtca agaaaaattc ggtaccaaga ctgaattgaa
     6661 gaacctcaac tccttctcaa acgttcgtaa aggtcttgaa tacgaagtcc aacgccaggc
     6721 tgaaattctt cgctcaggtg gtcaaatccg ccaagaaaca cgccgttacg atgaagctaa
     6781 caaaacaacc atcctcatgc gtgtcaagga aggggctgct gactaccgct acttcccaga
     6841 accagaccta cccctctttg aaatttctga cgagtggatt gaggaaatgc ggactgagtt
     6901 gccagagttt ccaaaagaac gtcgtgcgcg ttatgtatct gaccttggtt tatcagacta
     6961 cgatgctagt cagttgactg ctaataaagt cacttctgac ttctttgaaa aagctgttgc
     7021 cctaggtggt gatgccaaac aagtctctaa ctggctccaa ggggaagtcg ctcagttctt
     7081 gaatgctgaa ggtaaaacac tggaacaaat cgaattgaca ccagaaaact tggttgaaat
     7141 gattgccatc atcgaagacg gtactatttc atctaagatt gccaagaaag tctttgtcca
     7201 tctagctaaa aatggcggtg gcgcgcgtga atacgtggaa aaagcaggta tggttcaaat
     7261 ttcagatcca gctatcttga tcccaatcat ccaccaagtc tttgccgata acgaagctgc
     7321 tgttgccgac ttcaagtcag gcaaacgtaa cgccgacaag gcctttacag gattccttat
     7381 gaaggcaacc aaaggccaag ccaacccaca agttgccctt aaactacttg cacaggaatt
     7441 ggcgaagttg aaagaaaact agacagaaca aaaccagccc taaggttggt tttttcttct
     7501 ctaccaactc ccaataacta ttttggcttt atttccagag tattttatgg taaaatgaag
     7561 agtaataata tttattaaag aggtaaaaac atgattgaag caagtaaatt aaaagctggt
     7621 atgacctttg aaacagctga cggcaaattg attcgcgttt tggaagctag tcaccacaag
     7681 ccaggtaaag gaaacacgat catgcgtatg aaattgcgtg atgtccgtac tggttctaca
     7741 tttgacacaa gctaccgtcc agaggaaaaa tttgaacaag ctattatcga gactgtccca
     7801 gctcaatact tgtacaaaat ggatgacaca gcatacttca tgaatacaga aacttacgac
     7861 cagtacgaaa tccctgtagt caatgttgaa aacgaattgc tttacatcct tgaaaactct
     7921 gatgtgaaaa tccaattcta cggaactgaa gtgatcggtg tcaccgttcc tactactgtt
     7981 gagttgacag ttgctgaaac tcaaccatct atcaaaggtg ctactgttac aggttctggc
     8041 aaaccagcaa cgatggaaac tggacttgtc gtaaacgttc cagacttcat cgaagcagga
     8101 caaaaactcg ttatcaacac tgcagaagga acttacgttt ctcgtgccta atctctagaa
     8161 agaggtcatt ctatgggaat tgaagaacaa cttggcgaaa tcgttatcgc cccacgtgta
     8221 cttgaaaaaa tcattgctat cgctactgca aaggtagagg gtgttcactc tttttcaaac
     8281 agatcagtgt ctgataccct ttcaaaactt tcactcggcc gtggcattta tcttaaaaac
     8341 gtggacgaag aactcacagc agatatctat ctctaccttg agtacggagt aaaagttcct
     8401 aaggtagcgg ttgctatcca gaaagctgtc aaagatgccg tccgtaatat ggctgatgta
     8461 gaactcgctg ctatcaatat tcacgttgca ggtatcgtcc cagataaaac accaaaacca
     8521 gaattgaaag atctatttga cgaggacttc ctcaatgact agtccactat tagaatctag
     8581 acgccaactc cgtaaatgcg cttttcaagc tctcatgagc cttgagttcg gtacggatgt
     8641 cgaaactgct tgtcgtttcg cctatactca tgatcgtgaa tatacggatg tacaacttcc
     8701 agcctttttg atagacctcg tttctggtgt tcaagctaaa aaggaagaac tagataagca
     8761 aatcactcag catttaaaag caggttggac cattgaacgc ttaacgctcg tggagagaaa
     8821 cctccttcgc ttgggagtct ttgaaatcac ttcatttgac actcctcagc tggttgctat
     8881 taatgaagct atcgagcttg caaaggactt ctccgatcaa aaatctgccc gttttatcaa
     8941 tggactgctc agccagtttg taacagaaga acaataaaaa gaaaaagtgt ttgatagata
     9001 tcaaacactt ttttctttgc ctcccactat ctaaaaaaat gataatagat ataattgtaa
     9061 acaaaaatcc agataggttt tgcatgattg agaaagttaa aaaaactatg gcagagaatc
     9121 gttaatctca gattgtcggt agaacgataa acaagggcaa aaaagaaacc aatcagacta
     9181 taatataata aactaattgg atctctgtga gatagtatca aatggctaat cccaaagata
     9241 aggcctgata agatgacatc taaatagtac tttgacttag gaaagaaggt attcataaaa
     9301 taccctctat caagagtctc ctcaaaaaca ggaccgatga ttacaagcag gacaaaagat
     9361 aagatagtcg ataaaaaggt tggttgtcca tttgaaagaa ccacggtaaa atactcatca
     9421 tgaatattcc tatggttaat caaatgagca tagcgtgcct aaaaattacc gagaatctga
     9481 taaaccacat acgttgcaaa taagtagaag acaaatgacc agttccagct ctttttttca
     9541 aagataaaga gcatcttttt cttttttaac ctccaaatta atagaaggaa acttcccact
     9601 aataccattg ttaaaataag agaatagaca tcagctccta accctaaaat gatcgtcaca
     9661 tacaatccaa ttgtttgtgg taaataggta gatagtaaaa taataagcaa aaatattcca
     9721 aattgtctta gtttttttgt gtttctcatc gtactttttt gaaagattac cctgctcgga
     9781 agccgtactt ccaagcatct atataagaat taagtgcccc ttgcctcata taaggagcaa
     9841 attctctata atataaccat ctactatatc catcttccca aacagcaaga ccacctgaag
     9901 tttgctccaa gtcctcagtt gaaataactg taaatgtttc tgtagctgtc attgcaagta
     9961 ccttcttaaa atatagtg
//
LOCUS       DAVLGK010000065         9742 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLGK010000065 DAVLGK010000000
VERSION     DAVLGK010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9742
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.066"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..582
                     /locus_tag="VXE01_001994"
     CDS             <1..582
                     /locus_tag="VXE01_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0750846.1"
                     /translation="NKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKNVTK
                     NGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRINSGM
                     VILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQNEFA
                     DFVVQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            642..878
                     /locus_tag="VXE01_001995"
     CDS             642..878
                     /locus_tag="VXE01_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV0750847.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            875..1288
                     /locus_tag="VXE01_001996"
     CDS             875..1288
                     /locus_tag="VXE01_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV0750848.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSPSALNMIVNLPEQ
                     FVFGKPLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWISEHSVREKVKK"
     gene            1406..2371
                     /locus_tag="VXE01_001997"
     CDS             1406..2371
                     /locus_tag="VXE01_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0750849.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            2337..2918
                     /locus_tag="VXE01_001998"
     CDS             2337..2918
                     /locus_tag="VXE01_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0750850.1"
                     /translation="MSSIHTKNSSLKSKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSS
                     GKFLDKHDRVFEGYPAYGGNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWIS
                     DNAIYIKEFKNSDFNLVFLLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQ
                     NEFADFVALVDKSQFACEIAIKVWRNSLKFSII"
     gene            2947..6297
                     /locus_tag="VXE01_001999"
     CDS             2947..6297
                     /locus_tag="VXE01_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0750851.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSLLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(6803..7273)
                     /locus_tag="VXE01_002000"
     CDS             complement(6803..7273)
                     /locus_tag="VXE01_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0750852.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(7290..9563)
                     /locus_tag="VXE01_002001"
     CDS             complement(7290..9563)
                     /locus_tag="VXE01_002001"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV0750853.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSSQDVIREVVYVESRVDTDQKGLPDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVSLPHKIELEKPQLNLVQPQGKAELVAEAEEKLTHINSSYTLNDY
                     FLPRGFATLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNDRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYDLTVDLAQSMLTLPC"
BASE COUNT         3164 a         1581 c         2025 g         2972 t
ORIGIN      
        1 aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga taggggcaaa
       61 aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt aaatacaaag
      121 aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa aacaaaggat
      181 aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac aagaggtact
      241 gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg tataaattca
      301 ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat tatccatgtt
      361 ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca gttaccaatt
      421 acaaaattaa aaaaaatact tctccccctc cccccactag ccctccaaaa tgagttcgca
      481 gactttgtag tccaggtcga caaatcacaa ttggcaatcc aaaaatctct ggaagaactt
      541 gaaactttga agaaatctct gatgcaggag tattttggct gatattctgc cattgtaatt
      601 acggtaatga tttgttataa tacttcaaag gaggaaatca gatggtagta aaaacaagaa
      661 aacaaggaaa ttcaatcacc attacgattc caagtgaatt taatattcca agtggtgtta
      721 aatacgaagc gaaattgtta ccaagtggtg agattatctt tactcctgaa gaattggggc
      781 agcaggtttc ttatgtatct gatgatgcct ttgacttaaa tttagataaa atatttgacg
      841 aatacgacga tgttttcaaa gctttggtgg aaaaatgaca atctatttga cagaaaagca
      901 aattgaaaaa ataaatgctt tagcaattca acggtattct ccaaatgaga aaattcaaac
      961 agttagtcct tctgccttaa atatgattgt gaacttacca gaacaatttg tctttgggaa
     1021 gcctctttat ccaacaattt ttgataaagc aacgatacta tttgtccaat tgataaagaa
     1081 gcatgttttt gctaatgcta ataaaagaac tgctttcttc gttttggtca aatttttaca
     1141 attaaacggc tatcgttttt ctgtaacggt agaagaagca gtaaaaatgt gtgtaaccat
     1201 cgcagtagaa gctttaactg atgaaaaaat gacaagctac tccaaatgga tttctgaaca
     1261 ttctgttaga gaaaaggtca aaaagtaacc tagtatgctg gatttgaatg agcacaagaa
     1321 aataaatgaa cagacaatat tagaattctg taatgcagaa actgatattg tctcttttta
     1381 ttgatgaata agaaagtgag aaattatgga atcaaaagtt acaattatca tgcaagaaat
     1441 gttacctctt ttaaataatg aacaattact agcgttgaga gagagtttag aacatcatct
     1501 agtagacgga aaaaagcagc agaagtattc gaataataac ctgttgcaac tatttattac
     1561 cgccaagcag gtagagggct gtagctcaaa aacaattcgt tattaccaga ggacgattga
     1621 aaacttgttt aatgctatta aagagtctgt gacacaactc acaacagatg atttaaggag
     1681 ttatttagca aattaccagt ctgaaaagga ttgtagtaag gcaaatttag acaatattag
     1741 gcgtatattg tcttcttttt ttgcttggct tgagcaagag gaatatatca ttaaaaatcc
     1801 cattcgacgg ataaagaaaa ttaagactga gcaaaatgtg aaggaaactt atactgatga
     1861 acatttggaa attatgcgtg ataactgtga aaatttgaga gatttggcaa taatagacct
     1921 actagcatcg acaggtatgc gtgtagggga gcttgtacag ttgaatcgtt cagatattga
     1981 ttttgaaaac agagagtgtg ttgtctttgg taaaggaaag aaggagagac cagtatattt
     2041 tgacgctcgt acgaaaattc atttaagaaa ctatcttaac gacagaaaag atagtcaccc
     2101 tgctcttttt gtaacgttag ttggaaaagt ccagaggctt ggaattgctg gtgtagagat
     2161 tcgcttaaga aagttaggag acaaactcgg tatacaaaag gttcacccac ataagttcag
     2221 aagaacttta gcgactaagg caattgataa aggtatgcct atcgaacaag tccaaaaact
     2281 gctaggtcat agcaagattg acacaaccct ggcctatgcc atggtcaatc aaaataatgt
     2341 caagcattca caccaaaaat tcatctctta aaagcaaatc ccgatttaac gagatgtttg
     2401 gggatccttt aaataataac aagaaatttg cagtaaaaac gggacaacag tgttttaaat
     2461 tttcaagtgg aaaatttctt gataaacatg atagagtttt tgaaggttat cctgcctatg
     2521 gtggaaatgg cattgcttgg aaaagtcgaa aatatttaat tgataatcct actatcatca
     2581 ttggtcgtgt aggtgcatat tgtggtaatg taagaactac ccacggtaag gtatggataa
     2641 gtgacaatgc tatatatata aaagaattta agaattccga tttcaatctt gtatttttat
     2701 tagaattaat gaaagtaatt gattttagta aatttgctga tttctcaggt caaccaaaga
     2761 taactcaaaa accattagaa aatcagaaat atatcctccc ccctctagcc ctccaaaatg
     2821 agttcgcaga ctttgtagcc ctggtcgaca aatcacaatt tgcttgtgag atagctataa
     2881 aagtgtggag aaatagcttg aaatttagta taatatagct aaactatttg ttaaagtgag
     2941 aaaaaaatgg gaaattttag ctttctttta aaaaatgacg aatatgaatc tttttcaaaa
     3001 ccttgcattg aagctgagaa tatgattgct acatcaactg tggctactgc ctttatggcg
     3061 cgtcgtgctt tagagcaggc tgtccattgg atatatagtc acgattcata tttagaagct
     3121 ccctatcgtg ctactctatc ttctttagta tgggatgatg attttaggga tatcgtagat
     3181 tctgaactcc acaagcagat agttctgttg attcggtggg gaaaccatgc tgctcatggt
     3241 ggtgaaatta aggaacgaga agcgatttta gctttgcatc atttgtatca gtttgttaat
     3301 tttatcgatt attgttacag caatgagttt gtggagcgtt attttgatga gaagtgctta
     3361 ccactttcag caaacatcaa ataccgagaa actccacaat ctatgataaa gttacaagac
     3421 agtttaccag aactgcctga ttttcatgaa cagatggctg ctcagtccgt agaagttcaa
     3481 gagacttata ctgaaaaacg tgagactgca gcgcaacggc aagatgtgcc tttccatatt
     3541 gatcaattat ctgaggcaga gacaagaaag ctctttattg atatcgatct ccgtttagca
     3601 ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg ttgatggtct caagcacggt
     3661 tcaggaattg gttactgtga ctatgtactt tatggtaaaa atgggaaaat tttagcgatt
     3721 gtggaggcta aaaaagcctc tgtcaatcca gaagtagggg aagtacaggt caaagaatat
     3781 gctgaagctt tggagaaaca tatcggctat cagccaattt gctttattac aaatgggttg
     3841 aagcactata tacttgatgg tccgaaccgc cgccagattg caggctttta ctctcaagaa
     3901 gaattgcaat tagtgatgga tagacgtcat cttcaaaaac cgcttgagga tatttctagt
     3961 aaaattaggg acgatatttc cgggcgtcac taccaaaaac atgccattgc aagcgtttgt
     4021 gaagctttct ctaatcatcg tagacaggca cttttggtta tggcaactgg ggcggggaaa
     4081 actcgtacag cagtttctct agttgatatc ttatcacgtc ataactgggt aaaaaacgtt
     4141 ctcttcttag ccgatagaac ttccttggtt aagcaagcct atgattcgtt tagaaaatta
     4201 ctcccagatc tttccgtttg taacttctta gaagataaag aaggagctca atcaagtcgt
     4261 atggtctttt caacttatcc gaccatgatt ggagcgatta gtggtcaaga agaagtaaat
     4321 caacgccctt ttactgttgg gcattttgac cttatcataa ttgacgaatc tcaccgttct
     4381 atttatcaga aatacaagtc catttttgat tattttgatg caagaattgt aggcttaaca
     4441 gctactccgc gtcaagattt agataaaaac acctatggat tctttaattt ggagaatggg
     4501 gttccaacat atgcatatga tttggaagag gctgttaaag acggatattt agtagcctat
     4561 cattctatcg aaaccaaact gaaactacct acggatggtc tacattatga tgatttgtcc
     4621 gaagaagaaa aggaacattt tgatagcaaa tttgaagacg atagctgtga aaaagatatt
     4681 gatgggagtg tatttaattc ctttattttc aataaaagta cagtagaaat tgttttaaat
     4741 gaactcatga caagaggaat tcagacagcc tcgggtgatg aaattggtaa aactattatt
     4801 tttgctaaaa atcatgatca tgcggaatat atcagaggta tttttaacaa ccgctatcct
     4861 gaaaaaggga gcgactatgc tcaggtgatt gattatagta ttaagcatta tcagaccttg
     4921 attgatgatt ttaaaattaa ggagaagtat cctcaaattg cgatttctgt cgatatgtta
     4981 gatacaggta ttgatgtacc agaggttgtt aatttagtct tcttcaagaa agtacgctct
     5041 aaaactaagt tttggcagat gattggtcga ggaacccgtc tatgtaaaga tttatttgga
     5101 cctgagcagg ataaggaaaa cttcttggta tttgattatg gggacaattt tgattatttt
     5161 cgtgcagatc caagagatgg agagggtcgt cacattgttt cgctgactca gcgtttattt
     5221 aatatcaaag tggacttgat tcgagaactt cagggactcc aataccaaga agatcagttt
     5281 gcgagagcat accgtcagca gcttgtctcg gaacttcaag gtcgtataga gagcttaaat
     5341 gagttggact tcagggttcg tatggtttta gatacagttt atagctatag gaaattggaa
     5401 agttggcaga atctaactgc tgttacaagt gaaaccattc aaaaaaatct ctctctgctt
     5461 ttatttgatg aagataaaga agatgagatg gcgaggagat ttgatttgtg gttgcttcat
     5521 attcagttgg ggcaactgac agctaaatct tccactgttc atatttccca agtgatgaag
     5581 acggctagag ctctttctgc tattggcaat atcccgcagg tttttgagca ggctgaaatt
     5641 atcaggaaag tacaggagcc tgaattttgg aaagaagtta acttgtctga tttggaaaaa
     5701 attcgtcttg ctattcgaga tttattacag tttttggata aaacagaccg taaaccctac
     5761 tatgttaact ttgaagatcg tatactctcc actgttcacg agaccacagc atttttgcag
     5821 gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt atttgaaaac tcatctggat
     5881 gaggagtcca tttctaagct ataccataat aaaaagttga catctgatga tatgcttgca
     5941 cttgaaaaat tgctttggga aaaattaggt agtaaagcag actaccaaag tcattatgaa
     6001 aataaggcaa ttccgagatt ggttcgtgag attattggct tagatagaga gtctgccaat
     6061 cgtatttttt ctaaattttt gtcggatgag aatcttaatg ccaggcagat ttcatttgta
     6121 aaattgattg tagactacat tgtagaaaat ggttttttag agacgaaagt gttaacgcaa
     6181 gagccgttta aatcttatgg ttctgttcaa ctactcttcc aacaccaact accagtactt
     6241 cgtaatattg ttcaaatcat tgaacttatc aataatcgag ctggagaagc ggcttaaatt
     6301 ctaaagtgat tgccatgctg agactcattt aaaattaaaa agagtagaaa tttatgctat
     6361 atatgagaag ttttattagg aagaatgtca tcgttttcct agaatacagt atcagttgtt
     6421 aagtggttga taaatttcaa agtagatact tgtaccacga tgtttgttga tcgagttatt
     6481 aacaaaagag ctactttgat tttaaagaaa tagaaaacaa aaagccgagc aagaattcaa
     6541 ttgcaggaga aaatgaaata atactcaatg aaaatcaaag agcaaactag gaaactagct
     6601 gcaggctgct caaaacactg ttttgaggtt gtagatggaa gctgacgcgg attgaagaga
     6661 ttttcgaaga gtataaatct tcctaggata aagcaaaacg catagtatca agggttttca
     6721 acacttgata ctatgcgttt tctgatgtta aagactttct accaggtttt ttaaaagcat
     6781 aattgttagt tgtagtcatt tattattctt caaagaaaaa tggtggggcg aattttttca
     6841 gttcttcaaa gcacttttga gcagtatctg catcttcaca gatgataaga cagacatcat
     6901 taccacaaag ggtagcgata gcgtcaggga agctcaaagt atcaatgata gaaccaaagg
     6961 attgagccag tccaggaagg gtttttagta ggacttggtg ttgaactggg cgcatccaga
     7021 caagggcgtc ttccatgtag agttcgagac gtttttccca ttttgagatg gaaccattgt
     7081 taagaacata ataagcgcta tcttcttcgc ggacttttga taggttcata tttttgatgt
     7141 cgcgtgagag ggttgcctgg gttacttgaa tgtcgttctc agcaagaagg gcttgcaact
     7201 cagcctgtgt atgaatcttg ttttttgtga taagagcgcg tataagttgg tggcggtgtt
     7261 ctgatttatt cataataatg taactccttt tagcaaggta aggtaagcat ggactgagcg
     7321 aggtcgacag tcaagtcgta gtctgtattg tcacggatgg tgatttcaaa gtcagtagta
     7381 tagaggacta aacggagagt gtctccttct tttagcttgt aaatagttgg ctgcagttca
     7441 aattgaacgt ccatccattc atctgcagta atatcctcta ctaacagtaa atcatttcta
     7501 ttttgtaaat taaggtaacc ttttgtcacg actcgttgtg cctctggtct aaatggcaat
     7561 tcacagagat tttccaacat gtgatagcga ccgttgtcaa tggttctagc acttaaaata
     7621 gctggataag gttgtaggta tttcttttgc ccaaattcta gcagttgggc agataagagc
     7681 cccttgtttg tactggattt gatacgaaga ttgagctgag cgcgaccgtt taggtggaga
     7741 tctttagtca caggaaggtt aatagtaatc tgattggctt tcccttgata gagctctgta
     7801 ttgaaggttt ggtatgtctt accatagcgc tcaaaatcct tatctgggta ctggttttga
     7861 atagcttgct cttcttgacc aagtgagaag gtttcacagt tttcttgccc accgaagtta
     7921 tcaagtgata accaagtctg tggagctgta ttgtcctgcc agataacagt aggaagttga
     7981 aagtctgttt cctgtcctag taatttcttg gtcaataagg catttatgga ctcacggaag
     8041 tcaattgatt gccaattgtt catgtaaaca tgagcaccat tatggaaaaa gagatgcttg
     8101 tgtatatgag taggaagagc atggaacatc tggtaaacat gaagtggttt gacattccaa
     8161 tcctgagaac catgagtaaa gacaacctct gcctttactt tatgggcatt gagcagataa
     8221 ttgcggtcat gccaaaactg attgtagtcc ccagtttttc ggtctagctg agctttcact
     8281 ttttctaagt cagcttggtg agcttcattg ccacggatat agtcgccagc taagagatta
     8341 cgagaatagg ttaactcagc aagggagtca aagtcctcac ctggataacc acctgggcta
     8401 gtcaccagac cgttttcacg gtagtagttg taccatgatg aaattcctgc ctcggcaatg
     8461 ataacttcta aaccatcgac tcctgtagtc gcaagaccat tggacatggt acctagatag
     8521 gaaagtcccg ttgtagcaac ttttccgttt gaccaatcag ccttgacttg acgctggcgc
     8581 gtgtgatcag taaaggcacg gcaacggtcg ttaagccaat cgatgacatt tttataagcc
     8641 tcgatttgct ggtagtctcc attagtcatg aaacctgtcg agtctttggt accaacacct
     8701 gagacataga gagtggcaaa gcctctcgga aggaagtagt cgtttagtgt atagctagag
     8761 ttgatgtgag ttagcttttc ctcagcctct gctacaagct cagctttacc ttggggttgg
     8821 acgagattta gttgaggttt ctctagctca atcttgtgag gaagagaaac ctcaagctcg
     8881 ccctccatct tgtagagagc cttgtcacta gccttgtcat tggttccctg atgataaggg
     8941 ctggctgtca tgatggcagg gatttttcca tcaaaacgag ggcgaataat gctaaccttt
     9001 actaggtctg gtagcccttt ttggtcagta tcgacacgag actcaacgta aacgacttca
     9061 cgaatgacat cctggctaga aaaagtagcc aaactcttgc cgttaaagta gtggtagtca
     9121 ttatcctccg gaataagacc atcactaaca agttggtcga taagagtatt tccttttttg
     9181 gtgcgagtat tgagtaactg atagagattt tcaatcaagt caccatatat aatgggaaat
     9241 ccagtttctt tacgaaaaac gtcactatct tcgaagtcaa ccaaataaga aaagcctaaa
     9301 agttgaaaag caacagtata aaaaatatct gctgtcagtt catcttctga ttgaaaaaat
     9361 gtcagcaggt ctgttttttt atcagctgct aggatggaaa gtgggtagtt ggtgtcttga
     9421 taagtgaaaa agaaacgacg taaaaaggtt tcaagtgagt ctttgtgatt ggctgtattt
     9481 tgtaaatcaa agccacattt ttttagttca gataagacat tttcttttgg aaaattgata
     9541 taactatatt gattaaaacg catagaacct ccatatagaa tgacagttaa ggttattata
     9601 tcaaaaaaaa agcagaaagg gaattgttaa cttcaaaagg aaataatcca ataaaaatga
     9661 ataaagtact aaattcaata tagagaacag agtaacaata agaataaata gatagggtat
     9721 aaaagttcta ggagatttat at
//
LOCUS       DAVLGK010000066         9475 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLGK010000066 DAVLGK010000000
VERSION     DAVLGK010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9475
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.067"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            480..1523
                     /locus_tag="VXE01_002002"
     CDS             480..1523
                     /locus_tag="VXE01_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV0750854.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            1690..3777
                     /gene="topA"
                     /locus_tag="VXE01_002003"
     CDS             1690..3777
                     /gene="topA"
                     /locus_tag="VXE01_002003"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV0750855.1"
                     /translation="MATVTKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3998..4357
                     /locus_tag="VXE01_002004"
     CDS             3998..4357
                     /locus_tag="VXE01_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV0750856.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4450..5082
                     /locus_tag="VXE01_002005"
     CDS             4450..5082
                     /locus_tag="VXE01_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV0750857.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            5126..5782
                     /locus_tag="VXE01_002006"
     CDS             5126..5782
                     /locus_tag="VXE01_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV0750858.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5801..6895
                     /locus_tag="VXE01_002007"
     CDS             5801..6895
                     /locus_tag="VXE01_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV0750859.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGIAVANSLAAVKNGAGRVEGTINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKKQEITDADT
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6907..7944
                     /gene="leuB"
                     /locus_tag="VXE01_002008"
     CDS             6907..7944
                     /gene="leuB"
                     /locus_tag="VXE01_002008"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV0750860.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7941..8210
                     /locus_tag="VXE01_002009"
     CDS             7941..8210
                     /locus_tag="VXE01_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV0750861.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRTWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8214..8573
                     /gene="leuD"
                     /locus_tag="VXE01_002010"
     CDS             8214..8573
                     /gene="leuD"
                     /locus_tag="VXE01_002010"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV0750862.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8735..9358
                     /locus_tag="VXE01_002011"
                     /pseudo
     CDS             8735..9358
                     /locus_tag="VXE01_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
BASE COUNT         2942 a         1665 c         2097 g         2771 t
ORIGIN      
        1 actgttatag attcaataca ctataattta gtgtaattga gaaaggagaa atgattgtga
       61 ttgatgttgg ctaggttatg ttcaatgatt cctaccgtct caaatcttgt cagtaaggaa
      121 aaataaattc ttcaaaagta gagattacaa ggcttgttta agaaagaatt caaagacctt
      181 gacaaataaa aataaaatgg ttattataaa aaatggtctg aaatagatga tgatactttt
      241 cgaaaatctt tttacgtcag ctcagctttg ccttgctgtg ttttgagcaa gctacggtta
      301 gcttccgagt ttgattttca tttactagaa atgaaactga tgagagatat cagtagacat
      361 ttgagtcagg atattatgga aaatgataaa aagagctcgt gagattggca tatcagacta
      421 ctaaagtatt gagtttgtta ggattttagc gactagttag ctgggaaagg aagatatttg
      481 tgacaaataa taaactgtat tcgttgatag aatttagaaa taaaatatat gaagaattag
      541 aactttccag aagtgattta gcgattttac tatgtgccat gcttatcgcc tctatcggat
      601 taaatatgga ttcgactccc gtgattattg gagccatgtt aatctctcct ttgatgacac
      661 ctattctggg agtggggctc tctctagcta tatttgattt taaattgtta agaaaatctt
      721 ttaaaatatt agctattcaa attcttgcca gtctaatagc ttcaacactt tatttttatc
      781 tttctcccat ttcgtatgct agttcggaga ttgttgctag aacctctccg actatttggg
      841 atgttctcat tgcttttgta ggagggatag caggtattat tggtgctagg aaaaaagaga
      901 ccaataatat tgttcctggt gttgctattg caaccgcctt gatgcctcct ctttgtacag
      961 taggttatgc tattgcttct gctaatctaa aatttatcat aggctcctct tacctatttc
     1021 tcatcaattg tagctttatt gtcattgcga cttatatagg tgttaggttg atgatggtta
     1081 agaaacatta ttttaaagat aatgaagaag actctaaaat gcgtaggatt ttgcttctag
     1141 ttgctgtttt gctgatgatt ccgagtttca tctctgcaac gactttagtg agagaaacgt
     1201 tgaaaaaaga gtcccttaag aaatttatat cagagcagtt tcaggggcat aatattttga
     1261 aaaaaaccta ttctaaaaag actcataccc taaagctaac catttcagga aattatttga
     1321 cagaagaaga actcgatatg atttcaagta agagaggtga ctatggttta agtgatgttt
     1381 ctgttcaagt ttcacaattg tctgattcag aacaacttag taaggaagaa ctggtggagt
     1441 atttcttcca gtatatcaag gataaggaag caaaagaaaa ggaaaaagct aataagtttt
     1501 atacagagtc tgaggagcaa taatttcttg agaatagctg gtttttctcg tgagtcttct
     1561 atgtatatca aaggaagact gaggttttaa gtataaaact tttcttctat tatagtagct
     1621 aagtcttgac agggttcaaa aaatggttta cactttataa agtttattac tttgaaaagg
     1681 tgtgatactg tggctacggt aacaaaaaag aaaaaatcaa cagttaaaaa aaatctagtc
     1741 atcgtggagt cgcctgctaa ggccaagacg attgaaaaat atctaggcag aaactacaag
     1801 gttttagcca gtgtcgggca tatccgtgat ttgaagaaat ccagtatgtc cgtcgatatt
     1861 gaaaataatt atgaaccgca atatatcaat atccgaggaa aaggccctct tatcaatgac
     1921 ttgaaaaaag aagctaaaaa agctaataaa gtttttctcg cgagtgaccc ggaccgtgaa
     1981 ggagaagcga tttcttggca tttggcccat attctcaact tggatgaaaa tgatgccaac
     2041 cgtgtggtct tcaatgaaat caccaaggat gcagtcaaaa atgcttttaa agaacctcgt
     2101 aagatcgata tggacttggt cgatgcccaa caagctcgtc ggatcttgga tcgcttggta
     2161 gggtattcga tttcgcctat tttgtggaag aaggtcaaga agggcttgtc agcaggtcgc
     2221 gttcagtcca ttgcccttaa actcatcatt gaccgtgaaa atgaaatcaa tgccttccag
     2281 ccagaagaat actggacagt tgatgctgtc tttaaaaagg gaaccaaaca atttcatgct
     2341 tccttctatg gagtagatgg taaaaagatg aaactgacca gcaatgacga agtcaaggaa
     2401 gtcttgtctc gtctgactag taaagacttt tcagtagatc aggtggataa gaaagagcgc
     2461 aagcgcaatg ctcctttacc ctataccact tcatctatgc agatggatgc tgccaataaa
     2521 atcaatttcc gtactcgaaa aaccatgatg gttgcccaac agctctatga aggaattaat
     2581 atcggttctg gtgttcaagg tttgattacc tatatgcgta ccgattcgac tcgtatcagt
     2641 cctgtagcgc aaaatgaggc ggcaagcttc attacggatc gttttggtag taagtattct
     2701 aagcacggta gcaaggtcaa aaacgcatca ggtgctcagg atgcccatga ggctattcgt
     2761 ccgtcaagtg tctttaatac accagaaagc atcgctaagt atctggacaa ggatcagctc
     2821 aagctatata cccttatctg gaatcgtttt gtggctagcc agatgacagc ggccgttttt
     2881 gataccatgg ctgttaaatt gtctcaaaaa ggggttcaat ttgctgccaa tggtagtcag
     2941 gttaagtttg atggttatct tgccatttat aatgattctg acaagaataa gatgttaccg
     3001 gacatggttg ttggagatgt ggtcaaacag gtcaatagca aaccagagca acatttcacc
     3061 caaccgcctg cccgttattc tgaagcaaca ctgattaaaa ccttagagga aaatggggtt
     3121 ggacgtccat caacctacgc gccaaccatt gaaaccattc agaaacgtta ttatgttcgc
     3181 ctggcagcca aacgttttga accgacagag ttgggagaaa ttgtcaataa gctcatcgtt
     3241 gaatatttcc cagatatcgt aaacgtgacc ttcacagctg aaatggaagg taaactggat
     3301 gatgtcgaag ttggaaaaga gcagtggcga cgggtcattg atgcctttta caaaccattc
     3361 tctaaagaag ttgctaaggc tgaagaagaa atggaaaaaa tccagattaa ggatgaacca
     3421 gctggatttg actgtgaagt gtgtggcagt ccaatggtca ttaaacttgg tcgttttggt
     3481 aaattctacg cttgtagcaa tttcccagat tgccgtcata cccaagcaat cgtgaaagag
     3541 attggtgttg agtgtccaag ctgtcatcag ggacaaatta ttgagcgaaa aaccaagcgt
     3601 aatcgcctat tctatggttg caatcgctat ccagaatgtg aatttacctc ttgggacaag
     3661 cctgttggtc gtgactgtcc aaaatgtggc aacttcctca tggagaaaaa agtccgtggt
     3721 ggtggcaagc aggttgtttg tagcaaaggc gactacgagg aagaaaagat taaataagag
     3781 gaggggcccg aaagtaaatt tcaggctcct tttggttaga acttgacaaa atacatcatt
     3841 ttatgcgaaa ctagaagaag attattttat actcaatgag aatcaaagag caaattagaa
     3901 agctagtcgc aggttgctca aagcactact ttgaggttga agatggaagc tgacctggtt
     3961 tgaagagatt ttcgaagagt attaactagg agaagttatg cgtcttatct atctaattat
     4021 tggtttttta tcgctggcct tggctattgt tggggttgtt ttacccttgt tacctacaac
     4081 acctttcctt ttgttgtcta ttgcttgttt ctccagaagt tccaagcgat tcgaagactg
     4141 gctttatcat accaagctct atcaaacata tgtagctgat tttcgcgaga ctaagtctat
     4201 tacgcgtgaa cgaaagaaaa aaatcatcgt ctctatctac gtcttgatgg gaatttctat
     4261 ttattttgca cctcttttac cagtcaaaat cggtctgggt gctttgacca tctttatcac
     4321 ttattatctt ttcaaggtca ttccagacaa agaatagtta aaacagtagt tatttgcctt
     4381 gataaaattg aaagcatatt cataacaata tgatataata aatttgaagt aatattcaag
     4441 gagaatcaaa tgatttacga attttgtgct gaaaatgtga ctttacttga aaaagcgatg
     4501 caggctggag ctcgtcggat tgaactctgt gataatctag cagttggtgg gacaacaccc
     4561 agctatggag tgactaaggc agcggttgaa ctggcagcta actacgatac aaccatcatg
     4621 accatgattc ggccacgtgg tggtgacttt gtctataatg acctagaaat tgctatcatg
     4681 ctagaagaca tttgtttgac tgctcaggct ggaagtcaag gggttgtatt tggagcttta
     4741 actgctgata aaaagttgga taagcctaat ctggaaaagt taattgctgc atcaaaagga
     4801 atggaaattg tctttcacat ggcctttgat gaactaagtg atgaagatca accggaagct
     4861 attgactggc tcagtcaagc cggtgtcact cgtatcctaa ctcgtgctgg tgtgtctggc
     4921 gactccttag aaaaacgttt tgttcactat cacagaattt tggagtacgc taaaggtaaa
     4981 attgaaattc taccaggtgg ggggattgac cttgacaacc gtcaaacctt tattgaccag
     5041 gtgggggtaa cacaattgca tggtactaag gttgtttttt aaaaaataga aaggaactgc
     5101 tagccttggg tagcagtttt cacttatgtt tgaaattttt aaatcctatc aatttaatca
     5161 agaaaaggct catgattatg gttttataga aaatagcgaa gtctggacat atagttgcca
     5221 gattttgcaa ggtgactttg tcatgactgt gtccatcact gctgataatg tgaactttca
     5281 agtctttgac caagagactg gtgacctcta tcctcacgtt catatggaaa gcatgagggg
     5341 aagttttgtc ggaaatgtcc gtgaggcttg tctggagatt ctttaccaga ttcggaaggc
     5401 ttgttttgat gtgcaagatt ttatctgtca tcagactaag cgtatcatga ctcaagttca
     5461 ggaaaagtat ggaaaccagt tggagtatct gtgggaaaaa tcgcctgata cagctgtatt
     5521 gcgccatgaa ggcaatcaaa agtggtatgc cgtcttgatg aaaatctctt ggaataagct
     5581 ggaaaagggc agagaaggac aagtggaagc agtcaacctc aagcatgacc aagtagctaa
     5641 tttgctttca caaaagggga tttatccagc cttccatatg agcaagcgct actggattag
     5701 tgtgtccctt gatgatactt tatcagatga agaagtactg gaattgatag aaaaaagttg
     5761 gaacttaacc tctaaaaaat gaaatatttt aataattttc atgaactttc aattagctaa
     5821 atattcttta ctaaagaaat tttcagaaaa tataggattt accacaccag aggaatatgg
     5881 tgccatcttc aaatacctga ttgagaatgt caagacggat cgtcagatca tctattcgcc
     5941 tcactgtcat gatgacctcg gaatagcagt ggcaaatagc cttgctgctg tcaagaatgg
     6001 tgcaggacgt gttgaaggga ctatcaatgg tattagggag cgagctggaa atgctgcttt
     6061 ggaagaaatt gcagtggctc tcaatattcg ccaagattac taccaagtag aaaccagtat
     6121 tgtcctaaat gagaccatca atacgtcaga aatggtttct cgcttctctg gtattccagt
     6181 tcctaaaaac aaagccgtcg ttggtggcaa taccttctcc cacgaatctg gtattcacca
     6241 agatggagtc cttaaaaatc ctctcactta tgagatcatc acacctgaat tggttggtgt
     6301 taagattccg cttggaaaat tatctggtcg ccatgctttt gttgagaaac tgagagaatt
     6361 ggccctagat tttacagaag aggatatcaa accactcttt gctaagttca aggcactggc
     6421 cgataagaag caagaaatca cagatgcaga tactcgagct ttggtagctg gaaccatggt
     6481 tgaaaatcca gaaggcttcc actttgatga tttacaactt caaactcatg cagataatga
     6541 cattgaagcg ctcgttagcc tagccaatat ggatggtgag aaagtcgaat ttaatgcgac
     6601 agggcaaggt tccgttgaag caatctttaa cgctatcgat aagttcttta accaatctgt
     6661 tcgtttggtg tcctacacta tcaatgcggt aacagatgga atcgatgccc aggatcgggt
     6721 tttggtcact gttgaaaaca gagatacaga aaccatcttt aatgcagcag ggcttgattt
     6781 tgatgtgttg aaggcttctg ctattgccta tataaacgct aatacctttg ttcaaaaaga
     6841 gaatgcaggt gagatgggac gcagtgtttc ttaccacgat atgcctagtg tgtaaaggag
     6901 aaggctatgg caaagaaaat agtagctcta gtaggagacg gaattggccc agaaatcatg
     6961 gaggctggtt tagaagttct ggaggctcta gctgaaaaaa caggttttga ctatgagatt
     7021 gacagacgac cgttcggagg tgcagatatt gatgcagcag gacctccctt acctgatgaa
     7081 acccttaagg caagtaggga agcagatgct atcctactag cagctatcgg tagtcctcag
     7141 tatgatggag cagcggttcg ccctgaacaa ggcctgatgg ctctccgtaa ggaactcaat
     7201 ctttacgcta atattcgtcc tgtaaaaatc tttgacagtc tcaagtattt gtcaccactc
     7261 aaaccggaac gaatttctgg tgtagacttt gtcgtggtgc gtgaattgac aggcgagatt
     7321 tactttggag atcatattct tgaagagcgc aaagcgcgtg atatcaacga ctatagctat
     7381 gaggaagtgg agcggattat tcgcaaagcc tttgaaattg caagaaatcg cagaaaaatc
     7441 gttactagta tcgataagca aaatgttcta gcgacctcaa aactctggcg gaaagtagct
     7501 gaggaagtcg cacaggattt cccagatgta accttggaac accagctggt agactcagct
     7561 gctatgctta tgattaccaa tcctgctaag tttgatgtta ttgtaacgga gaatcttttt
     7621 ggagatattt tatctgatga atcaagcgtc ttatctggta cacttgaggt tatgccatca
     7681 gccagtcatt ctgaaaatgg accaagtctc tatgaaccta ttcacggttc agcacctgat
     7741 attgcaggtc aaggaattgc caatcctact tccatgattt tatcagttgc catgatgttg
     7801 agagatagtt tcggacgtta tgaggatgca gagcgtatca aacgtgctgt tgagacaagt
     7861 ctggcggcag gaattttaac gagagatata ggaggtcagg cttcaacaaa ggaaatgacg
     7921 gaagctatta ttgcaaggtt atgaagttag acgaaaaaat tactctagtc cttttgattt
     7981 ggaatgtcat cattttcttg atttatggca ttgacaaatt caaggcaaga agaagaactt
     8041 ggcgcatcca agagaaaatc ttactcattt tagcccttac ttgtggtggt tttggggcct
     8101 ggttagctgg aatcactttt caccacaaga ctcgaaaatg gtactttaaa acagtttggt
     8161 ttcttgggat ggtgaccaca ctagtagcct tatattttat ttggaggtaa tggatggcag
     8221 ggtcttcgag ggaacacgct gcttgggctc tagcggacta tggttttaag gtcgtgattg
     8281 caggatcttt cggtgacatt cattacaata atgaactcaa taatggcatg ttgccaatcg
     8341 ttcagcctag agaggttaga gagaaactag cccagctaaa accaaccgac caggtaactg
     8401 tggacttgga acaacaaaaa atcatctcac cagttgaaga attcaccttc gagatagata
     8461 gcaagtggaa acataaactc ctaaatagtt tggatgatat cggtattacc ttgcagtatg
     8521 aagagttgat tgctgcttat gaaaaacaac gaccagccta ctggcaggat tagaaaaaat
     8581 agaaaaggaa atatagtaaa ctgaaataag atgtaaacaa atgaattgga tcttaacatc
     8641 catttccagc aattttttag aaactacagt ggactattct ggattcaaca cattataaaa
     8701 ttatgacaaa acacattcac aagaaggcta cgacatttta aaaggtgagg gcggatgtat
     8761 cgtttgccct actaaagttg gttacattat catgaccagc aacaaggcag gacttgagcg
     8821 taagttcgca gccaaagaac gtaagcgtaa caaaccaggt gttgttctct gcggtagcat
     8881 ggatgaactt cgcgctttag cgcaactcaa cccagaaatt gaagcattct actaaaaaca
     8941 ttggatgaag atattcttct tggttgtatc cttccttgga aaccagaagc ctttgaaaaa
     9001 ctcaaagcat acggggatgg ccgtgaagaa cttatgactg atgtacgtgg tactagctgt
     9061 tttgttatca agtttggaaa agcaggtgaa caattggctg ccaagctttg ggaagaaggt
     9121 aaaatggtct acgcctcata tgcttcaatg acaaaacgat tgaaactcgc tatgagagca
     9181 aggtgtaatg gtgtctatgg tcgataagga cggcaaactc atcccagaac aaggaggagc
     9241 acgttcaact tcaccagcac cagttgtgat ccgtaaaggg cttgacattg ataaaatcat
     9301 gatgcacctg tcagatactt ttaactcatg ggactaccgt caggttgagt attattaaga
     9361 taaaaaaaga agtctagtgt tatgagatat taaagctcct aacactggac tttttgttta
     9421 gaatttcttt tctttttcta taggatatgg tattctatgt agaaaatata tgtta
//
LOCUS       DAVLGK010000067         9159 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLGK010000067 DAVLGK010000000
VERSION     DAVLGK010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.068"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            70..150
                     /locus_tag="VXE01_002012"
                     /pseudo
     CDS             70..150
                     /locus_tag="VXE01_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(427..1275)
                     /gene="dprA"
                     /locus_tag="VXE01_002013"
     CDS             complement(427..1275)
                     /gene="dprA"
                     /locus_tag="VXE01_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV0750863.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1371..2060)
                     /locus_tag="VXE01_002014"
     CDS             complement(1371..2060)
                     /locus_tag="VXE01_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0750864.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(2072..2950)
                     /locus_tag="VXE01_002015"
     CDS             complement(2072..2950)
                     /locus_tag="VXE01_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV0750865.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVVNGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2940..3809)
                     /gene="licA"
                     /locus_tag="VXE01_002016"
     CDS             complement(2940..3809)
                     /gene="licA"
                     /locus_tag="VXE01_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV0750866.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGYYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3826..4848)
                     /locus_tag="VXE01_002017"
     CDS             complement(3826..4848)
                     /locus_tag="VXE01_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0750867.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPSGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLL
                     LVGSSRSGRIDFENAIQMMKVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4853..5560)
                     /locus_tag="VXE01_002018"
     CDS             complement(4853..5560)
                     /locus_tag="VXE01_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV0750868.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVLHAEDLVDKYLPLHKERIIITKGGADRNTSIENIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIKLAQNHDAVDTVVEAVDTIVESTNGQFITGIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5895..7382
                     /gene="tacF"
                     /locus_tag="VXE01_002019"
     CDS             5895..7382
                     /gene="tacF"
                     /locus_tag="VXE01_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV0750869.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYSYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7392..8195
                     /locus_tag="VXE01_002020"
     CDS             7392..8195
                     /locus_tag="VXE01_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0750870.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8197..9006
                     /locus_tag="VXE01_002021"
     CDS             8197..9006
                     /locus_tag="VXE01_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0750871.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKYDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLIIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2867 a         1836 c         1551 g         2905 t
ORIGIN      
        1 ctataaatta atttgacttt cctgatagag ttgttcacat cttatttcaa ttcactatac
       61 tttcccttat actcaatgaa aatcaaagcg caaactagga agctagccac aggttgctca
      121 aagcactgct ttgaggttgt agataagact gacgaagtca gctcaaaata ctgttttgag
      181 gttgcagata agactgacga agtcagctca aaatactgtt ttgaggttgc agatggaagc
      241 tgacgtagtt tgaagagatt ttcgaagagt attatatgag aaaaatcctc tactctacta
      301 atccacttag aaaaaacgca tattatcaag tgttaaaaac ttgctaatat gcgttttatt
      361 atggaaatgt tgggttcatt ttctcttaaa attgattttt tcttagaatt ctagcttagg
      421 tcatttttaa aattcaaatt ccgcaagaac atcttgccca ctggtgacca attttgctcc
      481 ttcttgaatc aaatgatggc aaccgtctga tagtccatct aaaatgctac caggaatagc
      541 aaagacatcg cgtccttctt ccattgctcg ctcacacgta atgagactac ctgaacgcat
      601 cttagcctct gctacaatca caccacgaca aagtccagca atgatgcgat tacgggcagg
      661 aaaatgaaat ttcagaggtt gttcgccagg tccatattca cttaaaacca gatggtcatt
      721 gccgatgtag tcttgcaagc gtttattggc tttaggataa aacacatcca gtcctgttcc
      781 aatcactgca atggtttttc cgccattctg aagagctgcc atatgagctg ctgtgtcaat
      841 gcccttggcc agaccactga caataaccag ttcattttcc aagccttgaa tgactttttc
      901 aactgattta gctccctgtt tgctacaagc acgactgccc acgaccgcta ccttcgggaa
      961 tttcaggagg tcaagatttc ccttgtaaaa taaaagtaca ggcgcatcat atatttcact
     1021 caaatcccaa ggataacagt catctaaaat agagaaagat ggaaattttt gaaactcttt
     1081 cgacaaatgc gcatcgtcta tctgaaaata acgttccata aaaacggctg gattacgaca
     1141 acctgatata tctgcaatat cacccaacaa aagctcctga tcaacatttt caccgtattc
     1201 tagcactttc aaaatctgtt gattggtcaa acctgatttt tttaacttat agatttcata
     1261 gtttgtgatt ttcataaata actccatttc tttttctact catctatcta ttcgtaaaag
     1321 ttcgtaaaaa atcaaaaaac atccgactat tttgtcagat gttggaatct ttaattttcg
     1381 tttttaagaa tttcttctaa tttacgatag tcttggacac tatcgatctc ataaatgcta
     1441 ttgccttcta attcttcaac atagacatct agctctttga tattatcctt aaccatattg
     1501 tcccagtaga gatcaacaaa ttcgccactt gcataagcct tgtcgataaa gctgacaatc
     1561 ttttctgcag ttggagcatc ccagaaggat acaccactaa ggatgcgacc tgccttgcta
     1621 tcaacaataa tgtcttgaac cttgtagtca tctccataga ccaagaacca ttcgttggta
     1681 caatcttcac gataaacact aaaataagtc gaacgagtca aatcattgcg gaacatattt
     1741 ttaaagagat agttatctgc atcaataaca tagctgttgg ccaattcttc ttttacaaga
     1801 tagagagagt aaaagttatt gtagtcagcg tatttatcat tgaaaacgag gcgaacaccg
     1861 tatttttctt ttaagtaatc gaattgttct ttaagataac caacaatgat gatgatgtca
     1921 ttgattcctt tttctttgag aaactcaatt tggtattcaa tcaaaggttt ttgattaacc
     1981 tgaaccaagg ctttaggggt attttcagtc ataggacgca agcgagttcc caatcccgct
     2041 gctaagataa tggctttcac acgaatctcc tttattcttt aataataata taaactccag
     2101 caatgacgac aagtgacgtc ataatggtca gcatatctag cggtgcaccc aaaaaaacaa
     2161 ctgcaaacaa gaccgtccat actacatagc tcacgttcaa gcctgtagcc ttggctggtt
     2221 gcaagcgatt gatagcgata taataagcca agtaggaaat catatcaaag gctgcaaaaa
     2281 caatcatgag acctagcaat tgtccattga ctactgcagt aaatgactga tgagagaaga
     2341 gcacaatcac aagataggac aagaacgaag tcacttgacg gattaagagg gcttcgattt
     2401 cactcagttc actttccata gcaaaggagc taagaacact ctcacttccc catgcaatag
     2461 cacaaaccaa agcacagaga atcccaatgt agaaggaatt aacctgttca accttatagg
     2521 tctgggcaat aatccctcca ataatcaaga caatcccaaa tacagtattt ttcgaaatct
     2581 tgtgcttcaa aaagaagaaa gccaatagaa ctgaaatcgc agggtaaata gccgatacag
     2641 atgaagctaa agaacttccg atatacttaa ctgcataaag attggcctgc ataccgatag
     2701 ggcctgctag caaggctccg atgataacac tgacattgcg aatatttaag aaaattgaga
     2761 ggcgaacttt cccttctttt accaagagaa aagctagtaa gataaagatg ctcaaaaaat
     2821 catgagctgc agccaccaca aagggtgaca aatctgtaaa aatcgaaaag atataagcac
     2881 taaccgttag acccaagccc cagaaaatac ctgagagaag gccaaaagga actccgtttt
     2941 tacttttcat ctgatcctcc ataagaagcc aaacctttaa cagctctttg gtaacgattc
     3001 acaccatagt aaccaaaatc tgcaccttgc tcttccttat agacagtcca tagactccaa
     3061 atagtatctt gtaaaatttt ataaatagca atcttttcat gagaaaccgg tgtttggtca
     3121 ctctcatagt gagataagaa agtttcttcc tcttgggaag tgaattcaga ctctaaaaag
     3181 agggcagcca aatcccacat tggatcattc attgatgaat attcccagtc aatcaaataa
     3241 agtcgtcctt gaggtgattc gataaagttt tcaggcacca aatcgatatg acaagatttt
     3301 ctgtcaacac ctaagtcagc cagtcttttc tctaaggaga agactgcatt tctaacagat
     3361 tcatagttgg cataaggaat ttgttcttca atcaaggatt cgtatttttt gatttcttca
     3421 aaaggagcaa attctcctct taattcctta gcagatgtat gaatagtttg taatattgga
     3481 gcaattttgt cgaacttggt cttgattgac gttgaatcaa gcgtaatcgc agattcgata
     3541 tactcattta ctttgatgcc agcttcaata tcaaaaagat aattttttac atctaagcct
     3601 aaatccttta gtagttcaag attgtacttt tcatcttgtc gattgataag cttttctgtc
     3661 cctttaccaa agaatttaac aatgtattgc ttatttgttg ttttggccaa atagttttga
     3721 ttggtcattc cacccagttg ttcaacactg aggacttctt cttcttgact aagtaaggaa
     3781 gaaatttttt ctttaatgat tttctccaca attaacctcc aggacttata cttcccactt
     3841 aaacactgtt ttaaaggctg tgtttaaatc ggttgcaaag acacggtgaa tatctttaat
     3901 ttctcttaca ggttcttcta gataaaggat atttttaaga cgattggcaa atttcttgac
     3961 tttcatcatt tggatagcat tttcaaaatc aatgcgacca gaacgagatg acccaaccaa
     4021 gagcaagccc ttttctaagg catcgcgagt attgagattg actttatatt cgctaactcc
     4081 catcatgaga attgttccct gaggacgaat gtagcgaatc aagtcattaa tagctggtcc
     4141 agtaccatca ccaccacaac attcaaaagc atggtcaaag gccaactctt caggaatatt
     4201 atccgtaata tagcattctt tggcaaatga gaagagttcc aacttttccc aatgacgacc
     4261 aataaccaca atctctgctt ctggcaaagt atagttgata atattggcaa ccacaaaagc
     4321 taaacttcca tctccaataa cggcgatccg ctcccgcttg ctatgagcaa gagtcaatag
     4381 acgattcata gcgtgcatgc ccacactgac aaactctgta atggctgcaa ccgtatcttc
     4441 aatagcatca taagccacca cacgatcttt agggagagaa acaaactctc tcataaagcc
     4501 atcaaatcca ctagacaaga aatgggtccc tgtcatgtag ttttcataga attcttcatc
     4561 actctgcata ggagactgat tgggaatcat gacaactttt tgaccaacct cgtaggttcc
     4621 gctcgggtca gaaatgacgg ttccacatga ctcgtgaatc attgccattg gaagcttttt
     4681 attcaaaatc ttgggatcac gttttccctg gtagtaacgc tgatccgcat gacagacagc
     4741 catgtagttg ggacggataa ggatatgatt ctcttggtca atagcctctt cctgatattt
     4801 gacattgata aacttaggtt tagttagttg ataaatttga ttaatcattt tactagtctt
     4861 tctcaatcat actttttgca atcttcaaat ctgttacggt tgtaatcttc agatttgagt
     4921 attcgccttt ggccaaggct acatcttttc ctttgatcac aaagatttta catgcatctg
     4981 tcaagatttc cttctcttca tcagaaagag atccataaag gtccatgaag tccttgcaac
     5041 ggaatgtttg aggtgtttgt ccctgataga ggtgagcacg atttggaata cctgtaatga
     5101 attgaccatt ggtactttca acgatagtat ccactgcttc tactactgta tccactgcgt
     5161 catgattttg agcaagtttg atactgtctt gaatcatgcg aagcgtaata aatggacgaa
     5221 cagaatcgtg ggtaacaacg atatcctctg gagtaagcgg gcgataagca tcaatggctt
     5281 caatgatgtt ctcaatactt gtattgcggt cagcaccacc ctttgtaatg ataatacgtt
     5341 ccttatgaag aggaagatat ttatctacaa gatcttctgc atgtaaaacc cagtctccat
     5401 gaaccccaac tacaattttt tcaatacttg gttccaagac aaatttttca attgtatgaa
     5461 tcaaaatagg tcgatcacct agctctaaaa attgttttgg caagttactg attcccatgc
     5521 gtgtgccagt tccaccggca agaattcctg cataaatcat ctattttctc ctttgtctta
     5581 ctaaaaaact tattctctct attataccac aatctagtcc tatcatgaaa gaaatactgg
     5641 tcctcccctt ctagaatagg agaattatgc agttctatta ttcaaagaaa caagcctatt
     5701 tctagtaatg actaggaatt ctgtagcaat tactaataaa tgactgcgaa attttagagt
     5761 ccttcagaat aatatacttt ccttaaagaa aacttaatat ttaagatttg aaacttcaaa
     5821 gcgattgttt gacttgctgc ccttcatttc ttattagcta actttatgat ataatgaaaa
     5881 acgaggtaaa ttgaatgaaa agtataaaat taaatgctct atcttacatg ggaattcgtg
     5941 tcttgaatat tatttttccc atcctaactg gaacctatgt cgcgcgtgtc ttggaccgaa
     6001 ctgactatgg ttacttcaac tcagtcgaca ctattttgtc atttttcttg ccctttgcaa
     6061 cttatggtgt ctatagctac ggtttaaggg ctatcagtaa tgtcaaggat aacaaaaaag
     6121 atcttaacag aaccttttct agtctttttt atttgtgcat cgcttgtacg attttgacca
     6181 ctgctgtcta tatcctagcc tatcctctct tctttactga taatccaatc gtcaaaaagg
     6241 tctaccttgt tatggggatt caactcattg cccagatttt ttcaatcgaa tgggtcaatg
     6301 aagctctgga aaattacagt tttctctttt acaaaactgc cttcatccgt atcctgatgc
     6361 tggtctctat tttcttattt gttaaaaatg aacacgatat tgttgtctat acacttgtga
     6421 tgagtttatc gacgctgatt aactacctga ttagttattt ttggattaaa agagacatca
     6481 aacttgttaa aattcaccta agtgatttta aaccactctt tctccctctg acagccatgt
     6541 tagtctttgc caatgccaat atgctcttca cttttttaga tcgcctcttc ctcgttaaaa
     6601 cagggattga tgtcaacgtt agttactata ccatagctca gcgaattgtg accgttatag
     6661 ctggggttgt aacaggtgca attggagtga gtgtgcctcg tctcagttac tatctgggga
     6721 aaggagacaa agaagcctat gtttctctgg ttaatagagg tagtcgaatc tttaacttct
     6781 ttatcattcc actgagtttt ggactcatgg ttttaggacc aaatgccatc ctactttacg
     6841 gtagtgaaaa atatatcgga ggcggcatct tgacctctct cttcgctttt cgtacgatta
     6901 tcctggcctt agataccatt cttggttccc aaattctctt taccaatggc tatgaaaaac
     6961 gtatcacagt ctatacagtc tttgctgggc tactcaattt gggcttgaat agtctccttt
     7021 ttttcaacca tatcgtggct cctgaatact acttactgac aactatgcta tcagagactt
     7081 ctctacttgt tttctatatc attttcatcc atagaaaaca actcatccac ttgggacata
     7141 tctttagcta tactgttcga tactctctct tttcactttc ctttgtagca atttatttcc
     7201 tgattaattt cgtgtatcct gtagatatgg tcattaattt gccatttttg attaatactg
     7261 gtttgattgt cttgctatca gctatctctt atattagtct acttgtcttc acaaaagata
     7321 gcattttcta tgaattttta aaccatgtcc tagccttaaa aaataaattt aaaaaatcat
     7381 aggagtttaa aatgaaacaa ctaaccgttg aagatgccaa acaaattgaa ttagaaattt
     7441 tggattatat tgatactctc tgtaaaaagc acaatatcaa ctatattatt aactacggta
     7501 ctctgattgg ggcggttcga catgagggct ttatcccttg ggacgacgat attgatttat
     7561 ccatgcctag agaagactac caacgattta ttaacatttt tcaaaaggaa aaaagcaagt
     7621 ataagctcct atccttagaa actgataaga actactttaa caactttatc aagataaccg
     7681 acagtacgac taaaattatt gatactcgaa atacaaaaac ctatgagtct ggtatcttta
     7741 tcgatatttt ccctatagat cgctttgatg atcctaaggt cattgatact tgttataaac
     7801 tggaaagctt caaactgctg tctttcagta aacataaaaa tattgtctat aaggatagcc
     7861 ttttaaaaga ttggatacga acagcctttt ggttgctcct tcgaccggtt tctcctcgtt
     7921 attttgcaaa taaaatcgag aaagaaattc aaaaatatag tcgtgaaaat gggcagtata
     7981 tggcttttat tccttcaaaa tttaaggaaa aggaagtctt cccaagtggt acctttgata
     8041 aaacaatcga tttacccttt gagaatttaa gccttcctgc acctgaaaaa tttgatacta
     8101 ttttgacaca attttatgga gattatatga ccctaccacc agaagaaaaa cgcttctaca
     8161 gtcatgaatt tcacgcttat aaattggagg attaggatgc aatatttaga aaaaaaagaa
     8221 attaaagaaa ttcaactagc cctgctggac tatattgatg agacttgtaa gaaatatgat
     8281 attccttatt ttctcagtta tggaaccatg cttggagcca tccgccacaa aggtatgatt
     8341 ccttgggatg atgatattga tatttccctt tatcgtgagg attatgagcg tttactgaag
     8401 attattgaag aagaaaatca ccctcgctac aaggttcttt cctacgatac atcttcttgg
     8461 tacttccata atttcgcatc gattttggac acttctactg ttatagaaga ccatgttaag
     8521 tacaagcgtc atgataccag ccttttcatc gatgtcttcc caattgatcg atttacagac
     8581 ttgatcattg tcgacaagag ctataagtat gtggctcttc gtcaactagc ttatatcaaa
     8641 aaatcacgag cagttcacgg tgatagcaaa ctaaaagatt ttcttagatt atgtagctgg
     8701 tacgctctcc gatttgtcaa tcctcgctac ttttacaaga aaattgatca actagtcaaa
     8761 aatgctgtaa ccaacactcc tcaatatgaa ggaggagttg ggatcggtaa ggaagggatg
     8821 aaagaaatct tcccagttga tacctttaaa gaactgattt taactgagtt tgagggccgt
     8881 atgttgcctg ttcccaaaaa atatgaccaa tttttaaccc agatgtatgg cgattatatg
     8941 acaccaccat caaaagaaat gcaagagtgg tatagtcata gcattaaagc ttatcgcaaa
     9001 aactgattga gggggattat acaaactact aagatagagg ttattcaaaa acataatttt
     9061 agtagaaaat gaaatacata ttcccacaat aaaacgcatc atatcaaggt ttttgaaaaa
     9121 ccttgatatg atgcgtttta taattttaaa gactttttt
//
LOCUS       DAVLGK010000068         8677 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLGK010000068 DAVLGK010000000
VERSION     DAVLGK010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8677
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.069"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            18..1019
                     /locus_tag="VXE01_002022"
     CDS             18..1019
                     /locus_tag="VXE01_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0750872.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            1621..1701
                     /locus_tag="VXE01_002023"
                     /pseudo
     CDS             1621..1701
                     /locus_tag="VXE01_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            2051..2206
                     /locus_tag="VXE01_002024"
     CDS             2051..2206
                     /locus_tag="VXE01_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750873.1"
                     /translation="MEKLQFFLSQRACGCWKQAEKAVKLGSSETREENIILKGVPFIA
                     QPVTGDI"
     gene            2341..3702
                     /gene="trpE"
                     /locus_tag="VXE01_002025"
     CDS             2341..3702
                     /gene="trpE"
                     /locus_tag="VXE01_002025"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV0750874.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPQKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYLYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGAMDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKSTLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3699..4265
                     /locus_tag="VXE01_002026"
     CDS             3699..4265
                     /locus_tag="VXE01_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV0750875.1"
                     /translation="MILLIDNYDSFTHNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDKAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            4276..5280
                     /gene="trpD"
                     /locus_tag="VXE01_002027"
     CDS             4276..5280
                     /gene="trpD"
                     /locus_tag="VXE01_002027"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV0750876.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLAFK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5277..6044
                     /gene="trpC"
                     /locus_tag="VXE01_002028"
     CDS             5277..6044
                     /gene="trpC"
                     /locus_tag="VXE01_002028"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV0750877.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATVLGLEVLV
                     ETHNLAELEVAHRLGAQIIGVNNRNLTTFEVDLQTSVDLAKHFKDDCLYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAEDVAQRIKELQIDKG"
     gene            6031..6630
                     /locus_tag="VXE01_002029"
     CDS             6031..6630
                     /locus_tag="VXE01_002029"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV0750878.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEVAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            6608..7831
                     /gene="trpB"
                     /locus_tag="VXE01_002030"
     CDS             6608..7831
                     /gene="trpB"
                     /locus_tag="VXE01_002030"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0750879.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            7824..8600
                     /locus_tag="VXE01_002031"
     CDS             7824..8600
                     /locus_tag="VXE01_002031"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV0750880.1"
                     /translation="MPKTLTEKLNAIKVTGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(8572..>8677)
                     /locus_tag="VXE01_002032"
     CDS             complement(8572..>8677)
                     /locus_tag="VXE01_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0750881.1"
                     /translation="KLAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV"
BASE COUNT         2566 a         1626 c         2096 g         2389 t
ORIGIN      
        1 cgtaatggag gactgaaatg aaaaatataa atgggaaaaa ggtaactatt tatgatattg
       61 cacgtttatc aggtttttct ccaaaaacag tttcacgagt tattaatggt ggagtaaatg
      121 ttaaagaaga aacttatcaa gcgattcaaa aagttataga ggaattgtcg tatattccaa
      181 atgcgtatgc aaaaaattta actaaaaaag aagctataaa tatattgatt tctgtaaaaa
      241 aaatcgactc ttttccttta atttggtttc atacgctgtt agataaagtg ttacggacgt
      301 gtaaagaatt tggtgttaat gctatagttg agtactttgg agaggaggat acaattagta
      361 attcaattat atcaagcaca ggtagcctag tagatggtgt tattgttttt tatgaaagtg
      421 tagatgatat cagaattcag tatttaaaga agaaccatat gccttttctt gttttcggtg
      481 aatctcaaac gtctggagta gtctatgtat ctaataataa ttttcaagct acttatgata
      541 tgatgaaagc tgtaactgaa gaaaaattta aaaatatgtg gttgcttatg ggaggagaat
      601 cccatgttaa taaggatcgt gaaagaggtg tgcgttcttt tctgaatgat aaaaattact
      661 ttatggattt aaaagtcatt tatggcttat ctacaattga ttcagtttat tcttatgcaa
      721 tgcagcactt gactacccaa aattatccgg acattatttt tgtttcagga gatgaaaagg
      781 ttcagggctt gattcgtgct tgctatgaga aaggaattct tattccagat gatatttcta
      841 tcattggatt tgataatatt cctatttctc agtattatac tccagctttg tctacaattg
      901 ctcccaatta tgttaaattg gctaaagaaa tgatagaagg tgttttagca attattaaag
      961 gggaaagtgt cacatctgtt gaagtttctc ctaaatttgt taggagacag agtttctagt
     1021 attgtttaat tcttgaaaat cctagtggaa aagatggagt gttctaaaat aagttctgtt
     1081 tagcctccat tcagtttcta ttgagttgga tccaatttct aacgagtggg acatgttcat
     1141 gttcgatcta aggaagacat ggtcacattc gaatgatatt ttcaaaaaaa tcgtaaaaaa
     1201 gtcttgacaa agaaaaaaca aagtattaaa ataagttcaa caaatcagaa aagtaactat
     1261 ttttgatctt cagggagcct gtggtgattg tgaataggtg gttggaagta gtgaaagtgg
     1321 gctgattttg aaaatgaatt tgaaacaatg aaaattcggt gcgcacacct tacagtgcag
     1381 cttgttgtta aacaaggcag agatgtaaag ggataatccc tttataattg aggtggcatc
     1441 gcgttatcaa cgccctcaca cggaagtata ttctgtgtgt gggctttttt ctatccgtcg
     1501 tttggtttat cttttattag ggccttaagt cgctttgatg aacttgagtt ctatctacag
     1561 ctccttgcct actactaaaa gcaaacaaaa aggctggact aatacgaaaa aagctagtaa
     1621 tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgctc aaaacactgt
     1681 tttgaggttg tggatagaac tgacgaagtc agctcaaaat actgttttga ggttgtggat
     1741 agaactgacg aagtcagctc aaaacactgt tttgaggttg tggatagaac tgacgaagtc
     1801 agctcaaaac actgttttga ggttgtggat agaactgacg aagtcagctc aaaacactgt
     1861 tttgaggttg cagatagaac tgacgaagtc agtaaccata cctacggcaa ggcgacgttg
     1921 acgcggtttg aagagatttt cgaagagtat aaaggtgtac cgagatgaac atctcttcat
     1981 caatgtctct ggtcgtggag gcaaggacct agctgcgatt gcagactacc tagaagctaa
     2041 aaaataatag atggaaaaat tacagttctt tctctcacag agagcttgtg gttgctggaa
     2101 acaagcagag aaagctgtaa agttgggttc atctgaaacg agagaagaaa acatcattct
     2161 caagggagtg ccctttatcg cacagcctgt tacaggagat atctgagaca ggaatgagag
     2221 ataggagaaa tcctataatt gaggtggcac cgcgaatttc gtcctcacgc aagttatttt
     2281 gcgtggggat ttttcatata gtcaccacgg actagaagta gaactgaaag ggaaattaca
     2341 atggaacgaa tcattcatgg agatgtctta tcaccaatct tggcttatat gcgcttaaag
     2401 gggcaacaca aggttatctt agagagtatt ccgagagaca aggaaacagc tcgtttttct
     2461 atcttagcct ataatcctgt ttttgagatt aagtttgaaa atggagttct ttatcaaaat
     2521 ggtcaagtga ttgatcggga tcccttggat ttcctttatg aagtgattca taagagtcag
     2581 caccactcag agctaccttt tggtggtgga gccattggtt ttgtgggtta cgatatgatt
     2641 tcgctttatg aagaaattgg tcaaatccct gaggatacaa ttgggacgcc agacatgcat
     2701 ttctttgtct atgagagcta tatggtcttt gaccacaaga aggagaagat acatgtcata
     2761 gaggatgcac tttatagtga gcgcagtcaa gaagccttgg aaaaatcctt gaaccaagtg
     2821 cttgaggaat tacgcattcc tgctccaaat gaatttgaag acttggatct atctccgtta
     2881 gacttcaaac cccatatcgc tcctcagaag tttgaggaaa tggtggaaac cgctcgcgac
     2941 ttgattcgta atggcgatat gttccaatgt gtactcagtc agcgcttctc agcagaagtt
     3001 actggaaatc catttgactt ctacagaaat ctccgcgtga ccaatccatc caattacctc
     3061 tatttatatg actttgggga ttatcaaatc atcggtgcca gtccagaaag tttggtttct
     3121 gtcaaaaatg gcatcgtgac aaccaatccg attgcaggga cgcgaccaag aggggctatg
     3181 gatgaagaag acaaggcctt ggcgactgac ctcctctctg atgagaagga aacagcagaa
     3241 catcgaatgt tggtagactt ggggcgtaac gatattggcc gcatctctga aacggccagt
     3301 gtccaagtca ctaagtatat ggaagtggag ctcttccgtt atgttatgca tctgaccagc
     3361 gtggtcaagg ggcgtttgct tccagaactc actgctatgg atgccttgaa atcaacgctt
     3421 ccagctggaa ccgtttctgg agcaccaaaa attcgagcta tgagacgcat ctatgaactg
     3481 gaaacggaaa aacggggcgt atatgcagga gcaatcggct acttgtctgc gacgggtgat
     3541 atggatttgg ccattgccat ccgaaccatg attctcaaaa atcaaagagc ctatgtgcag
     3601 gctggggcag ggattgtcta cgactctatc gcccaaaacg aataccaaga aaccattaac
     3661 aaagcaaaat ctatgactag aattggagaa ctaagaccat gattttattg attgacaact
     3721 atgattcttt tacccataac ttggcccaat acattgggaa ttttgcagaa gttcaggttc
     3781 tgagaaatga tgattccaag ctgtatgaag aagctgaaaa agcagatggt ctggtctttt
     3841 ctcctggtcc tggttggcca gttgatgctg gaaagatgga agacatgatt cgtgattttg
     3901 caggcaagaa gccgattctt gggatttgtt tgggccacca agccattgca gaagtctttg
     3961 gtggtaagct aggtttggct ccaaaagtca tgcatgggaa acagagcaat atcaactttg
     4021 aagcgccatc tgttttgtat caaggtattg aggatggccg tgcggtcatg cgttatcaca
     4081 gtattttgat tgaggaaatg ccagaagact ttgaagtgac agctcgttcg actgatgaca
     4141 aagccatcat ggggattcaa cataaaaacc taccgattta tggcttccag taccatccag
     4201 agagcattgg aacgccagac ggcttgtctt ctattcggaa ttttatcgag aaggttgtaa
     4261 agtgaggaaa ctaggatgaa agagattatt gaaaaactag caaaatttga aaatttatca
     4321 ggtgtggaaa tgacggatgt cattgagcgt atcgtaactg ggcgtgtaac tgaagcgcag
     4381 attgcttctc tcctcttagc ttttaagatg aagggggaaa cacctgaaga acgcacagcc
     4441 attgcccaag tcatgagagg acatgcccag catattccaa ctgagattca tgatgctatg
     4501 gacaactgtg gtacaggtgg ggacaagtct ttcagtttta atatttccac aactgcagcc
     4561 tttgtcttgg ctggtggcgg tattcacatg gccaagcatg gtaaccgctc gatttcttct
     4621 aaatctggtt ccgcagatgt cctcgaagcc ttgggaatca atcttgacct caaaccagct
     4681 gaactaggta aggtctttga taaaactgga atcgtctttc tcttcgctaa aaatatgcac
     4741 ccagctatga aatacatcat gccagctcgt ttggaattgg gaattccaac gattatgaat
     4801 ttgactggtc cactgattca tccaatggct ttagaaacac agcttcttgg aattagtcgt
     4861 ccagaactcc tagaaagtac agctcaggtt ttgaaaaata tgggtcgcaa acgtgccatc
     4921 gtggttgctg gaccagaagg gttggatgaa gctggcttga acggaacaac caagattgca
     4981 cttcttgaaa atggcgaaat cagcttgtca agctttactc cagaggattt gggaatggaa
     5041 ggctatgcta tggaagatat tcgtggtggg aatgctcagg aaaatgcaga aattttgctt
     5101 agcgttctga aaaacgaagc aagtccattc ttggaaacga cagtcttgaa tgctggtctt
     5161 ggtttctatg ctaatggtaa gattgatagc atcaaggaag gagttgcctt ggcccgtcaa
     5221 gtgattgcta gaggcaaggc ccttgaaaaa ctcagactgt tacaggagta ccaaaaatga
     5281 gtcaggaatt tttagcacga atcttagagc agaaggcgcg tgaggtggag cagatgaagc
     5341 tggagcaaat ccagcctctg cgccagacct atcgcttggc agaatttttg aagaatcatc
     5401 aggaccgctt gcaggtaatc gctgaggtca agaaagctag ccctagtttg ggagatatca
     5461 atctcgatgt ggatattgtg caacaggccc agacttatga agaaaacgga gcagtgatga
     5521 tttcggtgtt gacagatgag gttttcttta aagggcattt ggattatcta cgggaaattt
     5581 ccagtcaggt agagattccg acgctcaaca aagactttat catcgatgaa aagcaaatca
     5641 tccgcgctcg caatgcaggt gcgacagtta tcttgctcat tgtggcagcc ttggcagaag
     5701 aacgtcttaa ggaactttac gactacgcga cagtgcttgg tctggaagtc ttggtggaaa
     5761 ctcacaatct agctgaacta gaagtggctc acagacttgg tgcccagatt atcggggtca
     5821 ataaccgcaa cttgaccacc tttgaggtcg acttgcagac cagtgtagac ttggctaaac
     5881 atttcaaaga tgattgcttg tacatttctg aatctgctat tttcacaggg caggatgcgg
     5941 aacgactagc cccatacttt aacggaattt tagtagggac agctctcatg caggcagagg
     6001 atgtggccca gagaatcaag gagttgcaga ttgacaaagg ttaagatttg tggactatcg
     6061 accaaagaag cggtggaaac agccgtttca gcaggagccg actacatcgg ttttgtcttc
     6121 gcacctagta aaagacaggt aactttagaa gaggtagctg agttggcaaa gcttattcct
     6181 gcagatgtga aaaaggttgg agtatttgtt tcaccaagtc gggtagaact gctggaagcg
     6241 attgacaaag ttggcttgga cttggttcaa gttcacggtc aggtggcaga tgatttattt
     6301 gagaatttgc cttgtgccag tattcaggct gtgcaggtag atggaaatgg gcatgtcccc
     6361 aattctcagg cagattatct actctttgat gcccctgtgg caggaagtgg ccagcccttt
     6421 gattggggtc aactggatac gactggacta gcacagccct tctttatcgc aggtggcctt
     6481 aatgaagata atgtagtaaa agcaattcaa cattttactc cctatgcagt agatgtatcg
     6541 agcggagtgg agacagatgg acaaaaagat catgaaaaga ttagaagatt tatagagagg
     6601 gtaaagcatg gcatatcagg aaccaaataa agatggattt tacggaaaat tcggcggacg
     6661 ttttgtccca gaaacattga tgacagcagt tttggagttg gagaaggcct accgtgaaag
     6721 tcaggcagac ccaagtttcc aagaggaatt aaaccagctt ttgcgccagt acgtaggacg
     6781 tgaaactcct ctttattacg caaaaaactt gacccagcat atcggcggag ccaagattta
     6841 tctcaaacgg gaagacctta accatacagg agcccacaag attaacaatg ccttaggaca
     6901 agtttggctt gccaaacgca tgggtaaaaa gaaaattatc gcagaaacgg gtgctggtca
     6961 gcacggtgtg gcaactgcaa ctgctgcggc cctctttaac atggaatgta ccatctacat
     7021 gggtgaggaa gatgtcaaac gccaagccct caatgtcttc cgcatggagc ttttgggagc
     7081 caaggtcgag gctgtaacag atggttcgcg cgtgctcaag gatgcggtca atgcagccct
     7141 tcgttcatgg gtggctaata tcgacgatac ccactatatc cttggttctg ccttggggcc
     7201 tcatccattt ccagaaatcg ttcgtgactt ccaaagtgtc atcggtcgag aggctaaaca
     7261 acagtaccgt gacttgacag gtcgagatct gccagatgcc ctagtagcct gtgttggtgg
     7321 tgggtcgaat gctatcgggc tcttccatcc ctttgtagaa gatgagtcag tagctatgta
     7381 tggaactgaa gcagcagggc ttggtgtgga tacagagcac cacgctgcta ccttgaccaa
     7441 gggtcgtccg ggtgttcttc acggttctct catggatgtg ctccaagatg cccatggtca
     7501 aattcttgaa gccttctcta tctcagcagg tttggactat cctggtatcg gtccagagca
     7561 ttctcactac cacgatatta aacgtgccag ctatgtccct gtgacagacg aagaagcctt
     7621 ggaaggattt caactcttgt ctcgtgtgga agggattatc ccagctttgg aatctagcca
     7681 tgctatcgct tttgcggtga aattggccaa agaacttgga ccagaaaagt ctatgattgt
     7741 ctgcctatca ggtcgtgggg acaaggatgt ggttcaagtc aaagaccgct tggaagcaga
     7801 tgcagcaaag aagggagaag ctcatgccta agacactaac agaaaaattg aatgctataa
     7861 aagtaactgg aaaaggaatt ttcgttcctt atatcatggc tggtgaccac gaaaaaggtt
     7921 tggacggtct tgctgaaaca attcactttt tagaagattt gggtgtctct gctattgaag
     7981 tggggattcc cttttcagac cctgttgcag atggacctgt tatcgaagaa gctggcttgc
     8041 gcagtttagc ccacgggacc tctacccagg ctttagttga aaccttgaaa accattgaaa
     8101 cagagattcc actggtcatc atgacctact tcaaccccct ctttcagtac ggtgtggaga
     8161 actttgtcaa agatctggct gatacagctg tgaagggctt gattatccca gacctgcctc
     8221 atgaacatgc caactttgta gaaccatttt tggcagatac agatatcgcc ttgattcctt
     8281 tagtaagctt gaccacagga attgagcgcc agaaagagtt gattgaaggg gcggagggat
     8341 tcgtctatgc cgttgccatc aatggggtga cagggaaatc aggcaattac cgtgcagatt
     8401 tggacaagca cttggcgcaa cttcatcaag tggccgacat cccagtcttg acaggttttg
     8461 gtgtatctag tcaagccgat ctggaacgct tcaatgcggt gtcagatggt gttatcgtcg
     8521 gttcaaaaat agtaaaagct ctccaccaag gagagccgat tcaggatttt atcagacaag
     8581 cagtagctta ccaaaaataa tcaaacaagt agcaagtaag aggaaaggca cgaaaggaag
     8641 tctttccttt ttcttttgca ggagaaaggc tagtttt
//
LOCUS       DAVLGK010000069         8485 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLGK010000069 DAVLGK010000000
VERSION     DAVLGK010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.070"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            104..790
                     /locus_tag="VXE01_002033"
     CDS             104..790
                     /locus_tag="VXE01_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0750882.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            791..1723
                     /locus_tag="VXE01_002034"
     CDS             791..1723
                     /locus_tag="VXE01_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0750883.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1734..2663
                     /locus_tag="VXE01_002035"
     CDS             1734..2663
                     /locus_tag="VXE01_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0750884.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2677..4116
                     /locus_tag="VXE01_002036"
     CDS             2677..4116
                     /locus_tag="VXE01_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750885.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4185..5762
                     /locus_tag="VXE01_002037"
     CDS             4185..5762
                     /locus_tag="VXE01_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0750886.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPKINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5822..7282
                     /locus_tag="VXE01_002038"
     CDS             5822..7282
                     /locus_tag="VXE01_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0750887.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNIEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPI
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            7304..7759
                     /locus_tag="VXE01_002039"
     CDS             7304..7759
                     /locus_tag="VXE01_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HEV0750888.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            7846..8252
                     /gene="cdd"
                     /locus_tag="VXE01_002040"
                     /pseudo
     CDS             7846..8252
                     /gene="cdd"
                     /locus_tag="VXE01_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            8265..>8485
                     /locus_tag="VXE01_002041"
     CDS             8265..>8485
                     /locus_tag="VXE01_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0750889.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVH"
BASE COUNT         2935 a         1117 c         1601 g         2832 t
ORIGIN      
        1 cctgataggg ctgttcatat cttatttcaa ttcactatat aaataaaatt gtagtagatg
       61 ttattgaatt agtaaaaaaa ataaaaaaac ggaggttttc tgaatggaaa ctaaaaaaat
      121 taaaaattta aaaggtcaaa taattgtttc ctgccaagcg ttagaaggag agccacttta
      181 tactccaaat ggaggagtga tgccgttatt agcaaaagcc gcctttcaag caggcgctaa
      241 aggtattcgt gctaattctg tccgcgatat ttcagaaata aaagaagaag ttgacttacc
      301 aattataggt atcataaaaa gagattacga tggctttgaa ccttttattt cagcaactat
      361 gaaagagatt gatgaattag ttagtgaagg agtagacatt ttagctttgg attgtactaa
      421 tcgttcaaga ccaggttatg ataatattac tgactttatt catgatatta aagtcaagta
      481 tccaaaccaa ttattaatgg ctgatatttc tacttttgaa gaagggaaag tagctgctga
      541 atcgggagta gattttgtgg gtacgacatt atctggttat acaccatata gccctaaaaa
      601 agataatcct gattttgagt tagttgaaag attggtaaaa gagcttgacg taccagttat
      661 tgctgaagga agaataagta ctccggaaca agctagaaaa atgttagatt taggtgctta
      721 cgcagtggtt gttggaggag ctatcactcg tcctttggaa atagcgaaga agtttattga
      781 ggtagtttag atgaatcaag aaatattaaa aaagagtaag attcaattga cagttgaaca
      841 tattcaaaaa tattggattt tatatttaat gatgattcca gcaactgttc tactaatttt
      901 atttacgtat ggaccaatgt acggcattat tatggccttt caagacttta ctgtcttcaa
      961 gggatatact ggaagtccat ttgtcggttt aaaacatttt caaagattgt tctcagatcc
     1021 tttgttttat agattgttca agaatacgtt catggtaggg gttttagact ttttattctc
     1081 tttcccagct ccgcttattt ttgcactcat attaaacgaa gtcagaaaag taagatttaa
     1141 gagtgtagtt caatctatta gttatcttcc tcattttatt cccctagtgg ttatggttgg
     1201 tattattttt gaactatttg gttcatatgg tattattaac agtttacttt catcacttgg
     1261 aatggagcca ataagtttct ttacaaaatc tgaatggttc ttgcctctct acattggttc
     1321 aggagtatgg aaaacaatag gttggggttc tatcatttat atgggagcat taaccaatat
     1381 agattcaact ttatatgaag cagcagatat ggacggggct aatagatggc acaaaatgtg
     1441 gcatgtaact ctaccaagtt taagacctac agtagttact ttgtttatac taaatgctgg
     1501 tggtatcatg caagtaggat ttgaaaaggt attcttgatg tctagtcctg caacatatga
     1561 agtatctgat gtattatcta cttatgttta tagacaaggt attttaaatt ctgatttcag
     1621 ttactcagct gcagtaggat tatttaataa catagtagct ttgttatttg ttttattagc
     1681 taataagatt gctaaaaaac ttggcgaaga aggaattgta taaggggggt aaaatgattt
     1741 tttcaaaaaa tacaaaaaag agtaatagag acaaagaaac cttcgttgat tatctcttta
     1801 tattcatttt aataataata accttactta tgttgtatcc attatggtgg gtagtgatga
     1861 cgtcactttc agaaccagtt tggctatcta aaaacgttgt taaattattt cccttaaaaa
     1921 tagatattac tgcatataag tttatttttg gggattctaa actatggcaa gcatatggta
     1981 atagtgtatt gtatgctgca ctatctacaa ttgttagtgt tgcggtatgt agtatgtatg
     2041 cctatccact tacaattcct gaaattaggg gtaaaaaatt ctggaatact cttattttga
     2101 ttccaatgtt ctttagtgga ggaatgatcc cgctttatat acaagttgca aacctcggtt
     2161 tattgaatac tgcttgggct cttgttttac ctggtgctgt ttctacatat tatataattt
     2221 tgtttagaac acagtttaaa tcaatcccaa tggagcttcg tgagtctgct agaattgatg
     2281 gggcaagtga atttagaatt ttttggaatt tagtattacc attatcaaaa gttattttca
     2341 tgattatagc actttattgc atagttggtt catggaatag ttttactcct ccattacttt
     2401 atttgaatga cgacactaag atgcctttat ctatttattt gagaaattta gttgttacaa
     2461 atacaactga tactgctgaa ttatcacttt ctgcaggtaa tacatattac caacaaattg
     2521 ctgctcaagg tggaggtatt ggtatgcgta ttgctattaa gatgggtact attgttgtta
     2581 gtgttattcc aattatgatg atttatccat ttattcagaa acattttgtt aagggaatcc
     2641 tgctaggttc tgtgaaaggt taataaggta attattttgc aaaatttaaa aaaatatctt
     2701 ttattagata gcggtttagt agttgggtat acattagaaa atgctcaatt aaaattaaat
     2761 aagctaaaaa aagatactga aaacaatcca ctatttggtg aagagtattt tgccgaaaat
     2821 cctaaattat gggaagttcg ttttgataat tcatatccaa acgttatcta tgataaagaa
     2881 ttgaaattat atagatgttg gtatcaaaca tttgttagtg atgaagcaag cgaagagact
     2941 cctttagcag aacgtggaga gaaggaatac attgtcaagt catctagaat gacagcactt
     3001 tgctatgctg aaagtaaaga tggagtaaaa tgggaaaaac caaatctcaa tctagtaaaa
     3061 tttaaaggtt caaaagataa taatattgtt ctgatgcatg cacacggtgc aggtatcatg
     3121 ctagatgaac aggagttgga tcctaagaaa cgatataaat tagtttcaaa attagaattt
     3181 tctccgaatc ttcattacat ggttgttgtt ttttcagaag acggtattca ttttgacgaa
     3241 cctattccat ggaaaaaatg gaatcctgca gcagatagtc ataattttcc atttagagat
     3301 ccaaaaactg gtaaatacgc tgttattaca agaacctggg caaataacgt acgtctaagt
     3361 gcaattactt tcagtgatga ttttattaat tggtcagaac ctaaagaaat ccttagggga
     3421 gatggatttg aagatcaaat ttattctatg ccagtaattt catacgcgga tatctattta
     3481 ggttttgctt caatgtacca cgaaggcgac actttaaatg aaaactatga taaagtagac
     3541 ttagaattga aattctctgc taatttggaa caatgggata gtgtatgtaa gggcgactat
     3601 ctcattgaaa ggggaggtgg agtatacccg cagaatgctg attttgatgc tagttgtatt
     3661 ttcacggctg ctccaataat tgaagatgat aagatttggt tctactatat gggtggaaat
     3721 ggtaatcaca ctggcttccg agaaagttca ttagctagag gatatattaa gaaagaccaa
     3781 tttgcttatt atactaataa gagagaagga attccagcta aaatatctac agttagcttc
     3841 caaacttacg atgatgaaat ttatatctta gctgatattc ctgaaaatgg ttatattaaa
     3901 gttgcggtag gtactaaata cggtaatgct tattcagatt ttggtcagga agatatctct
     3961 cttgttcaag tttccgatgg taagtataag ttggaattta ataaaaaatc tatcttagat
     4021 ttaggtaatt ctccagttgc gttcaaattt gaaatcgaga atgcaaaatt gtatggtatt
     4081 gaaggtagta ttcagcaaca ctatctcaaa tattaaccag aataattcgt taacaaataa
     4141 tctctatatt agtggagata gatatataaa atggaggtct tattatggta aagcttaata
     4201 aggtattaaa agggagtgtt gcattcctga gtgcaagttt attgctagca gcttgtggca
     4261 ataacgctaa ttcaaagccc gctgaaaaaa cagctgatgg taaaacgaaa atttcgtttc
     4321 tatctacatg gcaaattaat gatgttcgtc cgcctaaaga tgaaacactt gttggtcaat
     4381 ggttagaaga acagctaggt attgatattg atcttgtaac tattcctggc gagggagtaa
     4441 gttctaaagt aaattctctt attactagta accagttacc gactgttttg ttgacaacag
     4501 gagataagag tgatatcgct ggtatcaaca aacttggtaa acagggtgca ttcttagatt
     4561 tgtcacaaca catggacaaa ctaccaaact ataagaagta ccttgaaaaa aataatgcat
     4621 tagctcaaat agaagatgat gaaaaacata tttatgcttt cacaaaattc tttactgatg
     4681 agaatatcat gtatactaca ccaattctga gaaaagactt acttgttggt tcagaatttg
     4741 aagatctttc aaaaattaaa actgttgatg actatacaaa agttttgaaa tatttgactg
     4801 aaaaacaagg ttctccagca tttattcaac gtaatggcta tgaaggcttc atgaagcgag
     4861 ttacaccatt gtggaattta agccatcgta catactatga ctatgaatca gattcatata
     4921 aacatccagt tgaacaacct caattgaaac aattcgttga atggttgaaa gaattacgta
     4981 aagataacgt acttcaccct gactgggcag ttatgaaaga tgaaacttgg gaaggtctat
     5041 tggcttctaa caagggttca ttcactgttg accgtatgaa tatcattgga gataataact
     5101 ttgataaatc atttgattgg cagccacttg tttatccaaa aattaatgga aaacgttatt
     5161 tgcaaccgaa aacaccgtac atttctgatt caggttgggt aatcaatgcc aatgcaccaa
     5221 aagaagaaat tgataaagcg ttagaattct ttaatttctt atacgctgat gaaaatcaag
     5281 aaaaacttgc tattggattt gaaggtaaaa catttacacg tgaaaaccct aatactcaag
     5341 caggtattaa atggttgatt caaatttacg gtgaaaatgc tggaaatgat aaagcagaac
     5401 tgctgtttaa acatggtaac caagcattta ctcgcgttca aactaaatta gatattgagg
     5461 cacagccagg aacattccct aaagttatgt atgatcaagt agataaaatt aagaaagatt
     5521 taggtggttt tagaccagat actccggttc tttcctttac aactgaagaa ttagatgttt
     5581 taactaaatc tgaagcagga ttaaatactt tctttgatga aaatattatt aaattcattg
     5641 aaggacaaag agatatgagt gagtgggatt catttatcaa tgaagctaaa tctaaagact
     5701 tggataaagt tacaaaagta tataatgatg cctacaaacg tgtcaaagat agaatgaaat
     5761 agactaaatg gtagctctct ggtttttcag agagctacta ctgcctgagg gggagtaagc
     5821 tttgtatgat gtagtaatta taggtgcagg aagttcgggc gcattggctg caattgcttc
     5881 ggggcgtcta gggttaaaaa cttgtctaat agagaaggga agtagaattg gtggagttcc
     5941 tattaataca ctaatggggt catttgctaa tctatatttt gatgattctg gtagagtaaa
     6001 tgcaagtaaa attgttgggg aattaataga acgtattatc aaaaaaggtg gtactgtctt
     6061 taactctatg gaagaattga tgaatgtaaa tgatttttat cagattacaa ttccctatca
     6121 accagaagtt tatgaatcgg ttttaactga tatgttgatt gagtctaaag ttgatatttt
     6181 actaaatatt gaagttaata atattattta tgatagtaaa aatattaaaa gtcttgaaat
     6241 tttaagtaat caggaagtta aattgattga ttctaaagtt tttattgatg ctacagggaa
     6301 tgcaacaatt gcttctgcta gtggagctga tgtttatgaa aaaaattctt cttacggttg
     6361 tttaatgaga gttggaggag ttgatatctc aaagactata gaacatattg aaaaaacaaa
     6421 gcagtggaac tatatagaag gatataatca gtggttagaa gaagtattag caaatcgaaa
     6481 gtacagagcc actggagcag ttttaaaaga tccagtttct tatgatcatg cccctatgct
     6541 ttcaaaagac gaccatttta tgaatgatga aaaatggaat tacattaaag aaagatggga
     6601 aaaatttaga tttatttaca ctttagaagt atcactattt aggaatgaat taaaaaaagc
     6661 tgtagaatct ggggatttta attttgaaat ttatcatgat gataaatctg gagtcactat
     6721 gaatggcgac ggtataagct atggttcatg gggtcaaaat gtagcattaa ttaatgttgc
     6781 aaaagcattt ggattcaatc ccaaatatat ggaagatgaa tcacatgcta atattctttc
     6841 tagaaaatat aatttaacat ttttatcttt tcttaaaaaa tatgtaccag gttttgaaaa
     6901 ttcttttatc cttgatcagg gaactagagc taccaacaga tcatgtaggc acattgataa
     6961 ttcatctatg atggacgaaa ttcttgattt tccaatttat acatttaaga ctatgtatag
     7021 ctatcaaact cctaaagaaa taacgtacaa atcaattgta ggtggaaaat tgaataattt
     7081 gtttgtaata ggtaaaggtg cttaccaatc cgaaagtttt agatcacaaa ttagttgtat
     7141 gttaatgggg atatcatcgg cagcagcggc aaaaactatt attgaagata aaagcaatac
     7201 tctaaacatt aatagagatt tgtttaaatc gaacttagat atattattta catgggagtt
     7261 ttctaattgg attactgatt aacaaataat aagggaatat taaatgaatg atactaataa
     7321 aaatcaatac tttgtttatg aatttgatac tagctttgta gaaatgtctt attctcagtt
     7381 ttttgaagga tattgtattc ttttttcaaa agaaccctat ccttctttat ctgatatgcc
     7441 aatggaattt agaaaagaat ttttaatgga aatgagtata ttaggtgatg cgatgcttga
     7501 agtgttaaat gcctatagaa ttaattatga tatcttagga aattcaacac ctgtacttca
     7561 tgctcattta tttccgagat acatgtggga agaggaagag agaagaaaaa ctgtagttca
     7621 tagatatgat tcttcagttt ttagcaatcc tgagtttgaa tttactatag aaaagcatgg
     7681 accaattatt aaaaaactga ggtctgctat tgatagacat tatagagagt atcaacaatt
     7741 attagatgat tcaaactgaa ctccacattt tcgattagat ttaatacctt gtatattaca
     7801 actaggttgt ggatgatata attttttgaa aaatatattt taggaatgac ttataaagca
     7861 attatatcag aggctattaa atcaatggcc aaagcttatg ctccttattc tgattttaag
     7921 gttggagctg cgttagtaac tgaagataaa aaattttttc tggatgtaat atagaaaatg
     7981 ctgctttttc tcctacttgc tgtgcagaac gagtatcttt ttataaagct gtatttaaag
     8041 gagaacgttc gttttcaaga atatgtattg taggtggaaa aaatggtatc ttatcatctt
     8101 ttatagcacc ttgcggagtg tgtcgccagg taatgataga attttgtaat tctgattcat
     8161 ttgaagttat attggctagt gatgttgata cttataaagt atataaactt aaagaactac
     8221 taccagttag ttttaatcaa gaaaatttat aacaggaggg aactatggaa ttagttgaat
     8281 ttaaaaatgg acatgttaat acggttcatg agcatatcgc aataacgaaa gtaaaagagt
     8341 ttctaaataa tcatgatata ccaaaagata aaggtggcat acataaaatt tctactgatt
     8401 tcttttacaa tataattgat atggaaacta caactgaaga gaatagaccg tgggaaagtc
     8461 ataaggaata ttatgatgtc catta
//
LOCUS       DAVLGK010000070         8282 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLGK010000070 DAVLGK010000000
VERSION     DAVLGK010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.071"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(23..832)
                     /locus_tag="VXE01_002042"
     CDS             complement(23..832)
                     /locus_tag="VXE01_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0750890.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            complement(834..2183)
                     /gene="vicK"
                     /locus_tag="VXE01_002043"
     CDS             complement(834..2183)
                     /gene="vicK"
                     /locus_tag="VXE01_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV0750891.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     LLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            complement(2176..2880)
                     /locus_tag="VXE01_002044"
     CDS             complement(2176..2880)
                     /locus_tag="VXE01_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0750892.1"
                     /translation="MKKILIVDDEKPISDIIRFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            complement(2935..4110)
                     /gene="mutY"
                     /locus_tag="VXE01_002045"
     CDS             complement(2935..4110)
                     /gene="mutY"
                     /locus_tag="VXE01_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV0750893.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATASEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNIMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            complement(4438..6108)
                     /locus_tag="VXE01_002046"
     CDS             complement(4438..6108)
                     /locus_tag="VXE01_002046"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV0750894.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKLR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            6338..7027
                     /gene="coaB"
                     /locus_tag="VXE01_002047"
     CDS             6338..7027
                     /gene="coaB"
                     /locus_tag="VXE01_002047"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV0750895.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPESHPNLSIREITNTKDLLIEMQERVQDYQILIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNSTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            7039..7590
                     /gene="coaC"
                     /locus_tag="VXE01_002048"
     CDS             7039..7590
                     /gene="coaC"
                     /locus_tag="VXE01_002048"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV0750896.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLSLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            7574..8137
                     /locus_tag="VXE01_002049"
     CDS             7574..8137
                     /locus_tag="VXE01_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0750897.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
BASE COUNT         2454 a         1882 c         1485 g         2461 t
ORIGIN      
        1 gaacaccttc tcagcgttct ttctatatct ctgtcaatgg tgttgcggta tctggtgagg
       61 tatcataaac cttaaagtct actccgactc ccagatcagc ttgagccagc tgattgacca
      121 tggtcatatg agccagttcc ttgatattgt tttccttaga taaatgccca aggtaaatct
      181 tcttagtacg atttcctagc gtccgaatca tagcttcagc accgtcctcg ttagaaaggt
      241 gaccaaggtc agataggatt cgttgtttga gtcgccaagc gtaagaacct gatcgcaaaa
      301 tctctacatc atggttggcc tcgataagat agccatccgc attttcgaca atgcccgcca
      361 tacggtcact gacataacct gtatctgtca aaaggacaaa actcttgtca tccttcataa
      421 agcgatagaa ctgcggtgcg actgcatcat ggcttacacc aaaactctcg atgtcgatat
      481 ctccaaaagt tttggtttta cccatttcaa aaatatgctt ttgcgaagaa tccaccttgc
      541 caagatattt actattttcc atagcttgcc aggtcttttc attggcataa agatccatac
      601 catacttgcg agccaaaacg cctactccat ggatatgatc tgaatgctca tgggtaatca
      661 agatggcatc caggtcttct ggcttgcggt taatttcagc tagcagactg gtaattttct
      721 tgccagacaa gcctgcatcc actaaaagct tcttttttga ggtttccaga taaaaagaat
      781 ttccactgga acccgacgct aaaatactgt atttaaagcc tatttcactc attctagtct
      841 tctacttcat cctcccatac ttcttctttc actgcatcct tatcataagg gagcacaatg
      901 gtaaaggttg aacccttgcc gtattcactc ttggcccaaa taaagccctt atgttgtttg
      961 ataatttctt tagcgataga cagtcctaga cctgtaccac cttgtgcacg acttctagca
     1021 cgatccacac gatagaaacg gtcaaagata cgtggtaaat cctgcttagg aatccccaaa
     1081 ccgtggtcag aaatggataa aatcatctgg tcttcagttg tcttcattct gacagtgatt
     1141 ttacccccat ctggcgaata cttaatagca ttatttaaaa tattgtcgac aacctgcgtc
     1201 atcttatctg tatcaatttc catccagata gaattgatgg gataatctct caccaactca
     1261 tattttttct ccttttcctg tcctttcatc ttgtcaaaac gattgaggat aaaggtaata
     1321 aaagcagtga agttaatcag ttccacatct aggagactgg tagcattatc aatacgtgaa
     1381 agatggagga gatccgtcac catgcgcatc atacggttgg tctcatcaag agaaaccttg
     1441 ataaagtctg gtgctacagt ttcacacaaa gccccctcat ccaaggcttc aagataggat
     1501 tttacgctag tcagaggagt ccgtaactca tggctaacat tggaaacaaa gagtcttcgt
     1561 tctcgttctt ccttctcctg ctccgtcgta tcatgcaaaa cagccaccaa acctgaaata
     1621 aagccagact ctcgacgtat caaggcaaag cgaactcgaa ggttcaaata ttcgccattg
     1681 atatcttggg aatctagcaa caattctgga ctttgggtaa tcaaatcacg caattcatag
     1741 ttttcttcta tcttgagcaa ttccaaaatg cttctattca gaacatcttc cttaaccaac
     1801 cccagttgct tcttggctgt atcattaatc atgataatct gaccccgacg gttggtcgca
     1861 agaaccccat ctgtcatata aaacagaata ctatttagcc tcttactctc ttgttctaga
     1921 ttttcctgag tgagacgaat aacctccgac aagtcattca aattattggt aatattggtg
     1981 atttcagacc caccttgcat atcaagaacc ttggaataat ctcctgcaat caaatcttta
     2041 accttttgat tgatttgctt caactgaata ttatcacgtc tattttccag taataagagg
     2101 gtcacaacaa ggatgaaacc taacaaaatc aggataaaga taaaatctct ggtaaaaatg
     2161 gtttgtttca gtaaatcaag cattatttct catgtaatac cctacaccac ggcgcgtcaa
     2221 gatatactct ggtcggctgg gcgtatcttc aatcttctca cgcagacgtc gtacagtcac
     2281 atcaactgta cggacatcac caaaatagtc ataaccccag acagtctcaa gcaagtgttc
     2341 gcgcgtgatg acttgacctg tatgcgatgc taaatgatac aaaagctcaa attcacgatg
     2401 ggttaagtct agttcttcgc catatttttt agccacgtag gcgtctggaa caatttctaa
     2461 atccccaatt tggataggtt gaggtttact atctgcttcc tgaccatcta ctggcatagg
     2521 ttgagaacga cgcagaagag ctttaacacg cgcctgcaac tcacgattgg agaagggttt
     2581 cgttacatag tcatctgccc caagttccaa accgataacc ttatcaaatt cactatcttt
     2641 ggctgaaagc ataagaatgg gcacactgct tgtcttacga atggtcttag caacttctaa
     2701 accatcaatt tctggaagca tcaaatccag aataataata tctggttgct ctgcttcaaa
     2761 ttgctctagc gcttcacgac cattaaaagc agttacaact tcgtaacctt ccttggtcat
     2821 attaaacctg ataatatccg agattggttt ctcatcatct acaattagta tttttttcat
     2881 atgttcacct ttttctctac tattatacca aaaaatagtc agaagacaca atagctagtc
     2941 ttggctactg tctaagttgg cttgtgcata agcctgccag attttttgtt ggggtttggc
     3001 aagtgggtaa ttcttgaatt cttctggtga aagccaacga acttccctat ctgaaaaatc
     3061 atggaagtca ctcacctgac ctgctacaat ctgtacatgc cattttcgat gactaaaaac
     3121 atgctggact gtatcaaaac aaacatcaag ccaatcaaca tctaggtcat agtcctgctg
     3181 gaaactctct tctggactgg ggccaaagtt cacactttct tccgcaacct gatgaaagag
     3241 gtcaaactgc tcttcttgcg aaaagttatc aacttctata aaggggaaat gccaaaaacc
     3301 tgccaagagc ttttcgcttt catttttttc aagtaaaaat tgtccttgag aatttttcac
     3361 aactaaggct ttaagataaa taggaaccgg ctttttctta ggagatttaa ttggataacg
     3421 gtccatggtt ccattctgat atgccgcact aaagtccttg actgggcttt cttcaggtct
     3481 gggatttaca ggagactcaa tatcagaccc taagtccatc aaggcttgat taaaatcacc
     3541 cggacgatcc ggattaatca agatctccat cattgcctga aaaatttttc gattacttgg
     3601 aatcccaata tcgtggttga cttcaaacag acgcgccaag acccgcatga tattaccatc
     3661 tacagctggc tcaggcaagt taaaagcaat actggaaatg gctcctgctg tgtaaggtcc
     3721 aatccctttc aagctggaaa ttccttcata ggtatttgga aattggccac caaagtcagt
     3781 cataatctgc tgggctgcag cctgcatatt gcgaactcga gaataatagc ccaagccctc
     3841 ccaagctttc agtaaactct cctcagacgc agttgccaga ctttcgacag ttggaaacca
     3901 gtccaggaat ctttcgtagt aagggataac tgtatccacc ctggtctgct gaagcatgat
     3961 ttcagatacc cagatgtgat aaggattttt acttctcctc caaggcaaat ctcttttgtt
     4021 ttcatcatac caagcgagaa gtttctcacg gaaagaaatg actttctcct ccggccacat
     4081 gacgataccg tattctttca aatctaacat atctctagta taacacagaa ggtttcacct
     4141 gtctttgtat ctgatttata atattttcaa tagatagtat ataacttttc tatctactta
     4201 tactcaatga aaatcaaaga gcaaactagg aaactagccg caggttgctc aaaacactgt
     4261 tttgaggttg tggatagaac tgacagagtc agtatcatat acctacggca aggtgaagct
     4321 gacgtagttt gaaaagattt tcgaagagta taaatcttat tgatgaactg cttgcagtct
     4381 gagaaaaaat gagcttggat attatttcca aactcactta aagtcaattt caatccacta
     4441 gaacaagcct agtacagttc catcgctttc aacatccatg ttgagagctg ctggacgttt
     4501 tggaagacct ggcatggtca taacatcacc agttaaggca acgatgaagc ctgcacctaa
     4561 ttttggtacc aattcacgaa tggtaatttc aaagttttct ggtgctccaa gcgcatttgg
     4621 attgtctgag aaactgtatt gagttttagc catacaaatt ggcaatttgt cccaaccgtt
     4681 ttgaacgatt tgagcaattt gtgtttgagc tttcttctca aagttcactt tgctaccacg
     4741 atagatttca gtgacaattt tttcaatctt ttcttggaca gaaaggtcat tatcgtacaa
     4801 acgtttatag ttagctggat tttcagcaat tgtcttaaca actgtttcgg caagtgctac
     4861 tccaccttct gctccatcag cccagacact agccaattca actggtacat cgattgaggc
     4921 acagagttct tttaaggctg caatttcagc ttctgtatca gatacaaatt cgttaatagc
     4981 tacaactgct ggaataccga acttacggat attttcaacg tggcgtttca agttagcaaa
     5041 acctgcacga actgcctcta cattttcttc agtcagagcg tctttagcca caccaccatt
     5101 catcttaagg gcacgaaggg ttgcgacaat aacaactgca tctggagatg ttggcaagtt
     5161 tggtgtcttg atatcaagga atttctcagc accaaggtcc gcaccaaaac cagcttcagt
     5221 aacagtgtaa tcagccaagt gaagggctgt tgtcgtcgcc aaaacagagt tacagccatg
     5281 agcgatattg gcaaatggac caccgtgtac aaaggcaggt gtaccgtaaa ttgtctgaac
     5341 caagtttggc ttaatagcat ccttcaaaat caaagccaag gcaccctcaa cctgcaaatc
     5401 acctacagaa acaggcgtac ggtcatagcg ataaccaata acgatattcg ccaaacgaag
     5461 tttcaagtcc tcgatgtccg ttgccaagca aagaattgcc atgatttctg aagcaactgt
     5521 aatatcaaaa ccgtcctcac gtggaatacc gtttagagga ccaccaagac caacagtcac
     5581 atggcggagc gcacggtcgt tcaagtccac aacgcgtttc cagaggatac gacgttgatc
     5641 aattcccagc tcattccctt ggtgcaagtg gttgtcaatc aaggcagaaa gggcattgtt
     5701 ggcagttgta atagcatgca tatctccagt aaagtggagg ttgatgtctt ccattggcag
     5761 aacttgtgca tacccaccac cagcagcacc acccttgatc cccatgactg gaccaagaga
     5821 cggttcgcgg atagcaatca tggttttctt gccaatcttg ttcaaggcat ccgcaagacc
     5881 aatggtaagc gtcgactttc cttcacctgc aggtgttggg ttgatggcag taaccaagat
     5941 caatttaccg actggattgc tctcaactgc ccgaatttta tcaaagctga gtttagcctt
     6001 gtactttccg tacaactcca aatcgtcgta agaaatacca agtttctcta caacatcaac
     6061 aattggcttc aactcaatac tctgtgcgat ttcaatatct gttttcattc aaaattcctc
     6121 taacctctta tatgataatt cattatatca caaaacaaga tttttaacat cctaaaactc
     6181 tctaaacgtt cgtaaatatc tctgttttta agacttttag agtcctttct taaattttat
     6241 atggctttat agtttgaaac tataataaat cttcgttttt accaaaaatt tatcactttc
     6301 attttactta ccgcttattt ttgtgtacaa tagtgctatg aaaattttag ttacatcggg
     6361 cggtaccagt gaagctatcg atagcgtccg ctctatcact aaccattcta caggtcactt
     6421 ggggaaaatt atcacagaga ctttgctttc tgcagggcat gaagtttgtt taattacgac
     6481 aaaacgagct ctgaagccag agtctcatcc taacctaagt attcgagaaa ttaccaatac
     6541 caaggacctt ctaatagaaa tgcaagaacg tgttcaggat tatcagatct tgatccactc
     6601 aatggctgtt tctgactaca ctcctgttta tatgacaggg cttgaggaag ttcaggctag
     6661 ctccaatcta aaagaatttt taagcaagca gaatcatcag gccaagattt cttcaactga
     6721 tgaggttcag gttttgttcc ttaaaaagac acccaaaatc atatccctag tcaaggaatg
     6781 gaattctact attcatctga ttggtttcaa actgctggtt gatgttaccg aagatcatct
     6841 ggttgatatt gcacgaaaaa gtcttatcaa gaatcaagca gatttaatca tcgcgaatga
     6901 cctgactcaa atttcagcag atcagcaccg agctatattt gttgagaaaa atcagcttca
     6961 aacagtccag actaaagaag aaattgcaga actcctcctt gaaaaaattc aagcctatca
     7021 ttcttagaaa ggaaaactat ggcaaacatt ctcttggctg taacgggttc aatcgcctct
     7081 tataagtcgg cagatttagt cagttctcta aaaaaacaag gccatcaagt cactgtctta
     7141 atgactcagg ctgctacaga gtttatccaa cctttgtcac tacaggtact ctcacagaat
     7201 cctgtccact tggatgtcat gaaggaaccc tatcctgatc aggtcaatca tatcgaactt
     7261 ggaaaaaaag cagatttatt tatcgtggta cctgcaactg ctaacactat tgcaaaacta
     7321 gctcacggct ttgcggacaa catggtaacc agtacagctc tagccctacc aagtcatatt
     7381 cccaaactaa tagctcctgc tatgaataca aaaatgtatg accatccagt aactcagaat
     7441 aatctgaaaa cattagaaac ctacggctat cagctgattg ctcctaagga atccctacta
     7501 gcttgtggag accacggacg aggagcttta gctgacctca caattatttt agaaagaata
     7561 aaggaaacta tcgatgaaaa aacgctctaa tattgcaccc attgctatct tttttgctac
     7621 catgctcgtg atacactttc tgagctcact tatctttaac ctttttccat ttccaatcaa
     7681 accgaccatt gttcatattc ctgtcattat tgccagcatt atttatggtc cacgagttgg
     7741 ggttacactt ggatttttga tgggattact tagcttgacg gttaacacga ttacgattct
     7801 accgacaagc tacctcttct ctcccttcgt accaaacgga aacatctact cagctatcat
     7861 tgccattgtc ccacgtattt tgattggttt aactccttac ttagtctata aactgatgaa
     7921 aaacaagact ggtctgattt tagctggggc ccttggttcc ttgacaaata ctatctttgt
     7981 ccttggagga atcttcttcc tatttggaaa tgtttataat ggaaatatcc aacttcttct
     8041 ggcaaccgtt atctcaacaa attcaattgc tgaattggtc atttctgcaa ttctaaccct
     8101 agccattgtt ccacgactac aaaccttgaa aaaataaaaa caatctccgc tttcaaacct
     8161 gaaggtggag attttgctct atacagtttc tttttaatga aatctttact atagtaaaac
     8221 gaaataagaa caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
     8281 ag
//
LOCUS       DAVLGK010000071         8002 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLGK010000071 DAVLGK010000000
VERSION     DAVLGK010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.072"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            12..1487
                     /gene="galT"
                     /locus_tag="VXE01_002050"
     CDS             12..1487
                     /gene="galT"
                     /locus_tag="VXE01_002050"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0750898.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNKHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1500..2453
                     /gene="galE"
                     /locus_tag="VXE01_002051"
     CDS             1500..2453
                     /gene="galE"
                     /locus_tag="VXE01_002051"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0750899.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATNPYGYTKVMLEQILKDVHVADSEWSIALLRYFNP
                     IGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFGNDYDTLDGTGVRDYIHVVD
                     LAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFESVNKIPIPYKIVPRRSGDV
                     ATYYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNGYN"
     gene            2618..3277
                     /locus_tag="VXE01_002052"
     CDS             2618..3277
                     /locus_tag="VXE01_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV0750900.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIYMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3302..4369
                     /locus_tag="VXE01_002053"
     CDS             3302..4369
                     /locus_tag="VXE01_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0750901.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4472..5482
                     /locus_tag="VXE01_002054"
     CDS             4472..5482
                     /locus_tag="VXE01_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750902.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5494..7185
                     /locus_tag="VXE01_002055"
     CDS             5494..7185
                     /locus_tag="VXE01_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0750903.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7188..7898
                     /locus_tag="VXE01_002056"
     CDS             7188..7898
                     /locus_tag="VXE01_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0750904.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEITNIVGVIYVEEIS"
BASE COUNT         2694 a         1113 c         1580 g         2615 t
ORIGIN      
        1 aagaaaaata tatgaaaaca attattgata attttgttga tagagtaatt gaatacggaa
       61 tgtataatga aattgacaaa atatatgtga aaaatagagt actagcgtta ataggtgagg
      121 agggaattga tcgcatttcc gatgaaaatg acctgaaaca aataaaagat tacttagtgg
      181 aaatcgcctt aaaaaacggt aaaattaaag atttaatcga ggaaaaggaa tgtttaggag
      241 cagagttaat gaatttcata gttcctttac ctagtcgatt aaatgatatt ttttggagtt
      301 catatgatat atcacctcaa gaagcagttg aagagtttta taagttaagt aaagatagtg
      361 attatattaa aacttctgct attgctaaga atattgagtt tcgagcatca actaaatacg
      421 gagagctaga gattacgata aatttgtcaa aacccgaaaa agatccaaaa acaattgctg
      481 ctgaaaaatt agtaaaagca actaattatc ccaaatgttt actatgtatg gaaaatgaag
      541 gatatcaggg gcgaataaat tatccagcac gttcgaatca tagaattatt cggttgaaac
      601 ttggtgacga agtatgggga ttccagtatt ctccctactc gtactttaat aagcatgcga
      661 tatttttgaa tagtcaacat gtaccaatgg ctattacctc taaaacattt gaacaattat
      721 tggagattgt tgatattttg ccaggatatt ttgctggttc aaattctgat cttcctatct
      781 caggaggctc cattcttagt cataaccact accagggagg gaaacatatt ttcccaatgg
      841 aaaaagcaaa atttgagagt gaattttgtt ttaaagactt tgaggatgtt aatgctggta
      901 ttgtaaaatg gccaatgtca gtaattaggt tacaaagtga aaataaaaat cgcttgttag
      961 atttagctac taaaattcta aataagtgga gagaatattc agatttagaa gtagacatca
     1021 ttgctatgac tgaagatgtc ccacaccata cggtgactcc tattgctcgt aaagtggacg
     1081 ggagatacga attagatatt gttctaagag ataatcatac tactgaacaa tacccagatg
     1141 gtgttttcca tcctcatcaa gatgtacaac atattaaaaa ggaaaatatc gggttaatcg
     1201 aagtgatggg acttgcgata ttaccacctc gtttgaaacc agagttagaa gaagttggaa
     1261 aatatctttt aggagaggat aatgcaattg cggattatca tttagaatgg gccgaccaat
     1321 tgaaagaaaa atatcctcgc attaataaag aagaggttaa tagcgtagtt caacacgaag
     1381 caggacaagt gtttgcgaga gttctggaag atgcaggagt ttataagaat acaccgtctg
     1441 ggcatgaagc gtttatgaga tttgttaagt cggttggaat taattaggag gaaacccaga
     1501 tggcaatatt ggtaacaggc ggagctggtt atattggtag ccataccgta gtagaattac
     1561 taaatttagg aaaggaagtt atcattgtcg acaacctttc gaactctagc aaattggtgc
     1621 tagaccgtat tgaagcaatt acaggaatac gtcccgtgtt ttacgaatta gatgtttgtg
     1681 ataaacaagc attgagaaag gtatttgaac aagaatcgat tgatgctgca attcattttg
     1741 caggttataa agctgtcgga gaatccgtgc aaaagcctgt gatgtactac aaaaataata
     1801 ttatgagtac attggcactt gttgaagtga tgtcagaatt taatgttaaa aagattgtct
     1861 tttcttcaag tgcgacaaat ccttatgggt atacgaaagt gatgcttgag caaattttaa
     1921 aagatgttca tgtggcagat tcagaatgga gtattgcgtt gcttcgttat ttcaatccaa
     1981 ttggtgctca tgagtctggt ttgattgggg aagatccctc aggaattcct aacaacttga
     2041 tgccttatat tgcacaagta gcggtaggta agctatcaga gctaagtgtg ttcggaaatg
     2101 attatgatac gcttgatggt actggtgtgc gtgattatat ccatgtagta gatttagcaa
     2161 taggacatat aaaagcttta gaaaaagtat ctgaaaaaac agatgtttat atctataacc
     2221 taggctcggg agaaggcact agtgtattac aacttgtaaa tacatttgaa agtgttaata
     2281 agatccctat tccttataaa atagttccaa gacgttcagg agacgttgca acttattatg
     2341 caaatgcaga caaagcatat aaggaattaa attggaggac aacaaaatcg attgaagaca
     2401 tgtgtagaga tacatggaat tggcaatcaa aaaatcccaa tggctataat tgatgatact
     2461 gtctatatga gtgctgtatt ttggaaaaat tacttaatct tttaatgaaa gataaattta
     2521 aaaaaaatgt ttgacagcgc ttgacaaagg aaacggtttc attgtataat gtaaacacaa
     2581 tgacaccgat gtcaaatata aaaaagaagg tctttatatg aaaaacttaa caaaaattaa
     2641 gttcaaagaa aatggggaat ttaatcattt ccctgggaat acagttgtag caaatcttta
     2701 tactaaacaa gatttgatgg aagttgttga tattattcaa tcacgttata gagaattacc
     2761 atttatcgat aagtttactt taactccaag gaattctatt cacatgactg taattgaatt
     2821 gttgtgccat gaaaatcgtg aaacggagtt ttggagcagt aatcttcctc tagatacacc
     2881 tttacaggaa atacatgatt actttgctaa acaacttgaa atttttccat tgttggatga
     2941 agaaatttat atgcgtataa ctgaaatggg aaaacaaaac atactagttg aacctgcaga
     3001 tgaagcttct gcaaagagat tagaagaaat tcgtacttat gtctcagaaa aagcaggtgt
     3061 ttgtttccct aatcatgata gatatcaatt ccatatttca attgggtatc ttcggattcc
     3121 tctaaccgaa gaggaggaag aagagtttac taaagtcaga gcagaattaa ctgaaatttt
     3181 attagagaag attccaacta ttactgtaaa ccgtattgac tatactgtat ttgaagatat
     3241 gagacaattt gttccatatc acgaaaaatt taaataaaat aataaaaaag gagaacttat
     3301 catgaaaaaa atgaaagttt ggtctactgt acttgcaacg ggagttgctc ttactacact
     3361 tgctgcttgc tctggaggtt caaattctac gactgcttct tcatctgaag aaaaagctga
     3421 taaaagtcaa gaattagtaa tctattcgaa ctcagtctca aatggtcgtg gtgattggtt
     3481 gactgctaaa gcaaaagaag ctggttttaa tataaaaatg gttgatattg ctggcgctca
     3541 attagcagac cgtgttattg ctgagaagaa taatgcagtt gcagatatgg tatttggaat
     3601 tggtgctgtt gactcaaata aaattagaga tcaaaaatta ctagtacagt acaagcctaa
     3661 atggttagat aaaattgatc aatctttatc agataaagat aattattata atcctgtgat
     3721 tgttcaacca ttagttttaa ttggggcgcc tgatgtaaaa gaaatgccta aagattggac
     3781 tgaattaggt agtaagtata aaggtaaata ttcaatttat ggtcttcaag gtggtacagg
     3841 acgggcaatt ctagcaagta tcttagttcg ttaccttgat gaaaaaggag atttaggcgt
     3901 atcagaaaaa ggatgggaag ttgcaaaaga atactttgca aatgcctata ctcttcaaaa
     3961 aggtgaaagc tcagttgtta aagcgttaga taaagaaagc ccaattcaat acggtatgat
     4021 ctggggttct ggagcgttaa tcggacaaaa agaacaaaat gttgaattca aagttatgac
     4081 tcctgagatt ggtgtaccat ttgtaactga acaaactatg gttttaagca ctagtaaaaa
     4141 acaagcgtta gctaaagaat ttattgattg gtttggtcaa tcagaaattc aagtagaata
     4201 tagtaaaaaa tttggctcta tccctgccaa taaagatgcc ctaaaagagt tacctgaaga
     4261 tacgaaaaaa tttgttgatc aagtgaaacc acaaaatatt gactgggaag ctgttggaaa
     4321 gcatttggat gaatgggtag aaaaagctga attagaatac gtaaaataag aaataagagt
     4381 tattttttat gtccaagtct ctctattatt tctaaattta aggaagaaat aaagagaggc
     4441 ttttggttta gtaatagagg gagttagtga gatgattaaa tttgataata ttcaaattaa
     4501 atatggtgat tttgttgcaa ttgataatct gaatttagat atacatgaag gggaattctt
     4561 tacatttctt gggccttcag gatgtggtaa atcaactact ttgagagcat tggtaggttt
     4621 tttagatcca tcatcaggaa gtattgaagt taatggaaca gatgtcactc atttggaacc
     4681 tgaaaagcgt ggaattggta ttgtatttca atcttatgcg ctatttccaa ctatgactgt
     4741 ttttgataat attgcatttg gtttaaaagt taagaaggta gctccagatg ttattaaagc
     4801 taaagtatca gcagtggcag caaaaattaa gatctctgat caacagttac agcgtaatgt
     4861 atcagaatta tctgggggtc aacaacaaag ggtagcattg gctcgtgctc tggttcttga
     4921 acctaaaatt ctttgtctag atgaaccatt gtcaaacctt gacgcaaaat tacgtgtaga
     4981 tttgagaaaa gagttgaaaa gacttcaaaa agagttaggt attactactt tatatgttac
     5041 tcatgatcaa gaggaagcct tgactttatc tgatagaatt gcagtcttta acaatggata
     5101 catcgaacag gtcggtacac cagtagagat ttatcataat tctcaaactg aatttgtatg
     5161 tgattttatt ggagatatta atgttttgac cgatgaaaca gtccacgaag tattattgaa
     5221 aaatacaagc gttttcttag aggataaaaa aggatacatt cgattagaga aagttcgatt
     5281 caatcgtgaa actgaacaag attttattct aaaagggaca attattgatg ttgagttttc
     5341 tggagttaca attcactata caataaaagt ttctgaaagt cagattctta atgtaacaag
     5401 tattgatagt caggctgcta ttagatctgt cggagaaagt gtggaattat ttatcacacc
     5461 atcagacgtt ctgcaatttt aaggaggtgc agtatgcgtc ataaattaaa tttaaaagat
     5521 tggcttattc gtttagggtt aatctggttc ttagtaacat ttattattta tccaaacttt
     5581 gatctagtag tgaatgtatt tgtaaaagga ggagaatttt cccttgatgc tgtacatcgt
     5641 gttctaaaat ctcagagggc acttcagagt attatgaaca gttttaagtt agcattttca
     5701 ctcattatta cagttaatgt cgtaggtatt ctttgtgttc tatttacaga gtactttgat
     5761 attaaaggtg ctaaaatttt aaaattaggt tatatgacct ctttaattta tggaggagtg
     5821 gttttagcga ctggatataa atttgtctat ggtccttatg gattgattac aaaattttta
     5881 caaaatgtta tcccttcttt agactctaac tggtttattg ggtatggtgc agtcttattc
     5941 attatgacat tttcaggaac tgctaatcat acattgtttt taacaaatac aattcgaagc
     6001 gttgactatc acactattga ggctgctcga aatatgggag caaaaccatt tactgttttc
     6061 cgaaaagtag tgttaccaac cttaattcca actctatttg cacttactat tatggttttt
     6121 cttagtggtt tatctgcagt agcagcaccc atgattgttg gtggtaaaga atttcaaact
     6181 ataaatccaa tgattattac atttgcaggg atggggaatt ctcgtgattt agctgcctta
     6241 cttgcaatta ttttaggtat tgcaactaca attttgctta ctatcatgaa taagatagaa
     6301 aaaggtggaa attatatttc tatctctaag actaaagcgc ctcttaaaaa acaaaaaatt
     6361 gcgtctaagc cttggaatat cattgctcac attgtagcat atggattgtt cacagttttc
     6421 atgcttccac taatttttat agtattatac tcatttacag atccagttgc aattcaaaca
     6481 ggtaacttaa cattatcaaa ctttacttta gaaaattatc gcttattctt tagtaatagt
     6541 gcggcattct ctccattctt ggtcagcttt atttattcta ttattgctgc gacaacagca
     6601 acaattctcg cagttgtatt tgctcgtgtt gtcagaaaac ataaatctcg ttttgatttc
     6661 ttatttgaat atggtgctct acttccttgg ttactaccaa gtacactttt agcagtaagt
     6721 ttattattta cttttaatca gccacaattt cttgtcttga atcagatttt ggtaggtagt
     6781 ttggtaattc tacttattgc atatatagtt gtaaaaatcc cattttctta tagaatggta
     6841 cgtgctattt tatttagtgt tgatgatgag atggaagatg cagcaagaag tatgggtgct
     6901 tcaccttttt atactatgat gaaggttatc attccattta ttttaccggt tgttctctct
     6961 gttattgctt taaactttaa ctctttatta actgacttcg acttatctgt attcctttac
     7021 catcccctag ctcaaccatt aggtattacg attcgatctg caggtgatga aacagcaaca
     7081 tctaatgcac aagctctggt atttgtttat acaattgttc tgatgattat ttctggaacg
     7141 gtattatact tcacacaaag accggggcgt aaagtaagga aataatcatg acagccacta
     7201 gtcttgggtt atcaaatatt gaaatagttg tcaggattgt tttatcagta gtcattggta
     7261 gtataattgg tttagagaga gggagcaaat cccagcctgc aggcatccga acttatagta
     7321 ttgtttgtct agctgcatgt ttgattatga tgacgaatga atacgtatct tataaatttg
     7381 ggacaggaga tcctacacga ttaggagctc aagttatatc aggtgtgggt tttctaggcg
     7441 ctggaacgat tcttattaca gataaaaaga aaattacagg tctgacaact gcagcaggca
     7501 tttgggcttc ggcaggaatt ggattagcta ttggagtagg tttttatgag ggagctcttt
     7561 tagtagctat ttctgtttgg ggtgtgatat ccatgttcca accactaaaa aaatatctgc
     7621 aaaatcgttc taaaatgatt gaattgtata tagtggttaa atctacagaa gcctataatc
     7681 gtgtattggt ttattgtgca gaaaatggta tcagaatgac cgattcaaga acagcgtttg
     7741 gagatgttaa ttctgacaga attgaatact ttgatgttcc agataaaaaa atagcgtcat
     7801 ttattactct ggaattatca ggtagatttg aacatcttcg actgatggaa gaaattacta
     7861 atattgtagg tgttatttat gtcgaagaaa ttagctgaaa tttagtaaac aaagggacag
     7921 atgtttttgt ccttttgttt tttagatgtt ttaatcatct aatttttgag tagatttttg
     7981 ctcagaggtt tttatgaaag at
//
LOCUS       DAVLGK010000072         7603 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLGK010000072 DAVLGK010000000
VERSION     DAVLGK010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7603
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.073"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            25..870
                     /locus_tag="VXE01_002057"
     CDS             25..870
                     /locus_tag="VXE01_002057"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV0750905.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(1017..1719)
                     /locus_tag="VXE01_002058"
                     /pseudo
     CDS             complement(1017..1719)
                     /locus_tag="VXE01_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2067..4391
                     /gene="pflB"
                     /locus_tag="VXE01_002059"
     CDS             2067..4391
                     /gene="pflB"
                     /locus_tag="VXE01_002059"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV0750906.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(4449..5711)
                     /locus_tag="VXE01_002060"
     CDS             complement(4449..5711)
                     /locus_tag="VXE01_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0750907.1"
                     /translation="MEHINHTTLLIGIKDKNITLNKAIQHDTHIEVFATLDYHPPKCK
                     HCKGKQIKYDFQKPSKIPFIEIGAFPSLIRLKKRRFQCKSCRKVTVAETTLVQKNCQI
                     SEMVRQKIAQLLLNREALTHIASKLAISTSTSTVYRKLKQFHFQEDYTTLPEILSWDE
                     FSYQKGKLAFIAQDFNTKKIMTILDNRRQTTIRNHFFKYSKEARKKVKVVTVDMSGSY
                     IPLIKKLFPNAKIVLDRFHIVQHMSRALNQTRINIMKQFDDKSLEYRALKYYWKFILK
                     DSRKLSLKPFYARTFRETLTPRECLKKIFTLVPELKDYYDLYQLLLFHLQEKNTDQFW
                     GLIQDTLPHLNRTFKTTLSTFIRYKNYITNAIELPYSNAKLEATNKLIKDIKRNAFGY
                     RNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(5976..7505)
                     /gene="rlrA"
                     /locus_tag="VXE01_002061"
     CDS             complement(5976..7505)
                     /gene="rlrA"
                     /locus_tag="VXE01_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus transcriptional regulator RlrA"
                     /protein_id="HEV0750908.1"
                     /translation="MLNKYIEKRITDKITILNILLDIRSIELDELSTLTSLQSKSLLS
                     ILQELQETFEEELTFNLDTQQVQLIEHHSHQTNYYFHQLYNQSTILKILRFFLLQGNQ
                     SFNEFTQKEYISIATGYRVRQKCGLLLRSVGLDLVKNQVVGPEYRIRFLIALLQFHFG
                     IEIYDLNDGSMDWVTHMIVQSNSQLSHELLEITPDEYVHFSILVALTWKRREFPLEFP
                     ESKEFEKLKNLFMYPILMEHCQTYLEPHANMTFTQEELDYIFLVYCSANSSFSKDKWN
                     QEKKTHTIQLILQHTRGKHLLSKFKNILGNDISNSLSFLTALTFLTRTFLFGLQNLVP
                     YYNYYEHYGIESDKPLYHISKAIVQEWMTEQKIEGVIDQHRLYLFSLYLTETIFSSLP
                     AIPIFIILNNQADVNLIKSIILRNFTDKVASVTGYNILISPPPSEEHLTEPLIIITTK
                     EYLPYVKKQYPKGKHHFLTIALDLHVSQQRLIYQTIVDIRKEAFDKRVAMIAKKAHYL
                     L"
BASE COUNT         2269 a         1396 c         1536 g         2402 t
ORIGIN      
        1 taaatataat ataaggagaa atatatgtat cttattgaaa ttttaaaatc tatcttcttc
       61 gggattgttg aaggaattac ggaatggttg ccgatttcca gtacaggtca cttgatttta
      121 gcagaggagt ttatccaata ccaaaatcaa aatgaagcct ttatgtccat gtttaatgtc
      181 gtgattcagc ttggtgctat tttagcagtt atggtgattt attttaacaa gctcaatcct
      241 tttaaaccga ctaaggacaa acaggaagtt cgtaagactt ggagactatg gttgaaggtc
      301 ttgattgcca ctttgccttt acttggtgtc tttaaatttg atgattggtt tgatacccac
      361 ttccataaca tggtttcagt tgctctcatg ttgattatct acggggttgc cttcatctat
      421 ttggaaaagc gcaataaagc gcgtgctatc gagccaagtg taacagagtt ggacaagctt
      481 ccttatacga ccgctttcta tatcggactc ttccaagttc ttgctctttt accagggact
      541 agccgttcag gtgcaacgat tgtcggtggt ttgttaaatg gaaccagtcg ttcagttgtg
      601 acagaattta ccttctatct tgggattccc gttatgtttg gagctagtgc cttaaagatt
      661 ttcaaatttg tgaaagccgg agaactcttg agctttgggc aattgttttt gctcttggtc
      721 gcgatgggag tagcttttgc ggtcagcatg gtggctattc gcttcttgac cagctatgtg
      781 aaaaaacacg acttcaccct ttttggtaaa taccgtatcg tgcttggtag tgttttgcta
      841 ctttacagtt ttgtccgttt atttgtataa gaaaaacctt gaaggggcaa ctcttcaagg
      901 ttttatactc ttagaaaatc tcttcaaacc gcgtcagctt tatctgcaac ctcaaaacag
      961 tgttttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat tgagctttaa
     1021 aatccagtca gggtaatccc caataggcgg acacctcttt ctttctcgct taattcttca
     1081 tagagttgca gggctatttg gcttatctga ctagcatctt gtgttttttg agcaagactt
     1141 tttcgtttgg taagagttga aaagtcctcg tagcggattt tcaaaatgac aatttttcca
     1201 gctttttctt gttgatgtag attgagagcg actttttctg atagaagagt cagctctttt
     1261 ttgatatctt cctcagcacg gagaatcttc ccgtaggttt tctccttgcc gattgattta
     1321 cggatgcgat tggatttgac tggagagttg tgaatgccac gagcctttcg atacagatca
     1381 tagcctagtc taccaatctg tatagcgctt aaaaatagct cgaatctgga gtcccacaga
     1441 cttgtatttc tcataattcc ctgagataaa gacagcctgg ggacaacgtt cataagcttc
     1501 cttggaactc atggcagaat ggacaccaaa agctcttgcc tcataactac aggtagaaac
     1561 gactccccgt ccacctgttt gccgagggtc gcttccaata atgacaggtt ttcctctgag
     1621 tttaggatta tccctgattt ccactgcagc aaaaaaggca tccatgtcaa tatggatgat
     1681 ttttcttgac aaatcattta acaaaggaaa aatcaacatg cctagcacct ttttatactc
     1741 ttcgaaaatc tcttcaaacc acgtcagctc tatctgcaac ctcaaaacag tgttttgagc
     1801 aatctgcggc tagcttccta gtttgctttt cgatttccat tgagtgttac tgcttatttt
     1861 cttttattat accctttttt ctgaaaaaaa gaaaaaagga ctttattttt tcaaaaatat
     1921 aatacagttt gaaataaaat atagactgtt ttagaaaaga aagtgtaaaa atagggaatt
     1981 ttcacttgtt gaaatcggtt actatatggt atacttgtct tatgaatgta acagatgact
     2041 gttactagaa aaaagaggac attaatatgg ttgttaagac agttgttgaa gcacaagata
     2101 tttttgacaa agcttgggaa ggcttcaaag gcgtagattg gaaagaaaaa gcaagtgtat
     2161 cacgatttgt acaagctaac tacacacctt atgatggaga cgaaagcttc cttgcaggac
     2221 caacagagcg ttcacttcac atcaagaaaa ttgtagaaga aactaaagca cactacgaag
     2281 aaactcgttt cccaatggac actcgtccaa catctatcgc tgatatccct gctggattta
     2341 tcgacaaaga aaatgaagtt atcttcggta tccaaaacga tgaactcttc aaattgaact
     2401 tcatgccaaa aggtggtatc cgtatggctg aaactacttt gaaagaaaat ggatacgaac
     2461 cagacccagc tgttcacgaa atcttcacta aatatgtaac aacagttaac gacggtattt
     2521 tccgtgccta cacttcaaat attcgtcgcg ctcgtcacgc acacactgta actggtcttc
     2581 cagatgcata ctcacgcgga cgtatcatcg gtgtttacgc acgtcttgct ctttacggtg
     2641 cagactactt gatgcaagaa aaagtaaatg actggaatgc aatcaaagaa atcgatgaag
     2701 aaacaatccg tcttcgtgaa gaagtaaacc ttcaatacca agcattgcaa caagttgttc
     2761 gcctgggtga cctttacggg gttgatgttc gcaaaccagc gatgaacgtg aaagaagcaa
     2821 tccaatgggt taacattgct ttcatggctg tctgccgtgt gattaacggt gctgctacat
     2881 ctctaggtcg tgtaccaatc gtattggaca tctttgcaga acgtgacctt gctcgtggta
     2941 catttactga atcagaaatc caagaattcg ttgatgattt cgttatgaaa cttcgtacag
     3001 ttaaatttgc tcgtacaaaa gcttatgacc aattgtactc aggtgaccca acctttatca
     3061 caacttctat ggctggtatg ggtaacgacg gtcgtcaccg tgttactaag atggactacc
     3121 gtttcttgaa cactcttgac aacatcggta actcaccaga accaaacttg acagttcttt
     3181 ggactgacaa attgccatac aacttccgtc gctactgtat gcacatgagc cacaaacact
     3241 cttctatcca atacgaaggt gtaacaacaa tggctaaaga cggatatggt gaaatgagct
     3301 gtatctcatg ctgtgtgtct ccacttgatc cagaaaatga agaacaacgc cacaacatcc
     3361 agtacttcgg tgctcgtgta aacgttctta aagcccttct tactggtttg aatggtggtt
     3421 acgacgatgt tcacaaagac tacaaagtat ttgatatcga accaatccgt gacgaagttc
     3481 ttgaatttga atcagttaaa gcgaactttg aaaaatctct tgactggttg actgacactt
     3541 acgtagatgc cttgaacatc atccactaca tgactgatag gtacaactac gaagctgttc
     3601 aaatggcctt cttgccaact aaacaacgtg ccaacatggg attcggtatc tgtggatttg
     3661 ctaacactgt tgatacattg tcagctatca aatacgctac agttaaacca atccgtgacg
     3721 aagatggcta catctacgat tacgaaacaa tcggtgacta cccacgctgg ggtgaagatg
     3781 acccacgttc aaacgaattg gcagaatggt tgatcgaagc ttacacaact cgtctacgta
     3841 gccacaaact atacaaagac gcagaagcta cagtatcact tttgacaatc acatctaacg
     3901 ttgcttactc taaacaaact ggtaactcac cagttcacaa aggtgtatac ctcaacgaag
     3961 atggttctgt gaacttgtct aaacttgaat tcttctcacc aggtgctaac ccatctaaca
     4021 aagctaaagg tggttggttg caaaacttga actcactttc tagccttgac tttagttatg
     4081 cagctgacgg tatctcattg actacacaag tatcacctcg cgctcttggt aagactcgtg
     4141 atgaacaagt tgataacttg gtaacaatcc ttgatggtta cttcgaaaac ggtggacaac
     4201 acgttaactt gaacgttatg gacttgaacg atgtttacga aaaaatcatg tcaggtgaag
     4261 acgttatcgt acgtatctct ggatactgtg taaatactaa atacctcact ccagaacaaa
     4321 aaactgaatt gacacaacgt gtcttccacg aagttctttc aatggatgac gccttggatg
     4381 cattgagcta atcaagttct tgaataataa aaagggctct ttgtcaactg tagtgggttg
     4441 aagaaaagct aagctcgaga aaggacaaat tttgtccttt cttttttgat gttcagagcg
     4501 atgaaaatcc gttttttgaa gttttcaaag ttccgataac caaaggcatt gcgcttgatg
     4561 tctttgatga gtttgttagt ggcctcaagt ttagcgttag aataaggcaa ttcaatggcg
     4621 ttagtgatgt agtttttata gcgaataaat gtgctcaaag tggttttaaa ggtgcggttg
     4681 agatgaggta acgtgtcttg aattaagccc caaaactggt cagtattctt ctcttgtaga
     4741 tgaaatagga gtagttgata caggtcatag taatctttaa gttcaggtac tagagtaaag
     4801 attttcttca gacactccct aggagttaag gtctctctga aagttctagc atagaaaggc
     4861 ttaagagaga gtttccgact atcttttagg ataaatttcc agtaatattt aagagctctg
     4921 tattccagag atttatcatc aaattgcttc atgatgttga ttctagtctg attaagagcc
     4981 ctgctcatgt gttggacaat gtggaaacga tcgagaacaa ttttagcatt gggaaataat
     5041 ttcttaatga gagggatata acttccagac atatcaacag tgacgacttt aacttttttt
     5101 ctagcttctt tcgagtactt gaagaaatga tttcggatgg ttgtttgacg tctgttatca
     5161 agaatggtca tgattttctt agtgttgaaa tcctgagcaa tgaaagccaa tttccccttc
     5221 tggtaggaga attcatccca ggagaggatt tcaggcaaag tggtgtaatc ctcttggaaa
     5281 tgaaattgct tgagcttacg atagacggta gaggtagagg tagagatggc taatttagaa
     5341 gcgatatgtg taagagcctc tctgttgagt aggagttggg caattttctg tctcaccatt
     5401 tccgagattt ggcaattttt ctgaacgaga gttgtttcag ctacagtgac tttccgacag
     5461 gacttgcatt gaaatcgtct ctttttcaaa cgaatgaggc tagggaaagc accaatctcg
     5521 ataaaaggga ttttagaagg cttttggaag tcgtatttga tttgttttcc tttacagtgt
     5581 ttacatttag gtgggtgata atcaagtgta gcgaagactt cgatatgggt atcgtgctga
     5641 atggctttat ttaaggtgat gtttttgtct tttattccga tgagtaatgt ggtatgattg
     5701 atgtgttcca taagatactt tctaatgagt tgtttaggcg cttttcatta taagtcttat
     5761 gggacttttt tgatactcaa aaagccctat aatctccaca gtgggattta cccactacag
     5821 aaattataga gccagaaaaa acacttttgt tcactagcag aaactagaga gcagaagtgt
     5881 ttttctgttc agatttaccc aaaactggga aatatgggga taagaataga gatggcttag
     5941 gaagcccctt tttgtgtgta gacagtacga tgaacttata acaaatagtg agccttttta
     6001 gcaatcattg cgacccgttt gtcaaaagcc tcttttcgga tatctacaat tgtctgatag
     6061 atgagacgct gttggctaac atgcaaatct aaggcaatcg tcaaaaagtg atgtttccct
     6121 ttgggatact gctttttaac gtaaggcagg tattctttcg ttgtaataat aatcaatggc
     6181 tctgtcaaat gctcctctga aggaggagga ctaattagaa tattgtatcc tgtaacagag
     6241 gcaactttgt cagtaaaatt ccgtaaaata atggacttta ttaagtttac atctgcttga
     6301 ttatttaaaa tgataaaaat cgggatagca ggtagtgagg aaaagatggt ttctgtcaag
     6361 tagagtgaga aaaggtacag ccgatgctgg tcgataactc cttcaatctt ctgctcagtc
     6421 atccactctt gaacaattgc tttcgaaata tgatacagtg gcttgtcgct ttcaatccca
     6481 taatgttcgt aataattata atagggaact agattttgta aaccaaacaa aaacgttctt
     6541 gttaagaaag tcagtgctgt taaaaaagaa agagaattcg aaatgtcatt tcctaagata
     6601 ttcttgaact tggatagtag atgctttcct cttgtatgct gaagaatcag ttgaatagta
     6661 tgagtctttt tttcttgatt ccatttgtcc ttggaaaacg aagaattagc agaacaataa
     6721 accaaaaaga tataatccag ttcttcctga gtaaaagtca tgttggcatg tggctctaag
     6781 taagtttggc aatgttccat caaaatcgga tacataaaga ggttttttaa tttttcaaac
     6841 tctttggact cagggaactc aagtggaaat tcccgacgtt tccaagtgag tgccactagt
     6901 atgctaaaat gaacatactc gtcaggtgtg atttctaaca gttcatgact gagttgagaa
     6961 ttagactgca caatcatatg tgtgacccaa tccatacttc catcattcaa atcataaatc
     7021 tcaataccaa aatgaaactg gaggagtgca attaaaaaac gaatgcgata ttcaggacca
     7081 actacttgat ttttcacaag gtccaaacct actgaacgta gtaacaagcc acacttttgt
     7141 cgtacgcggt agcctgttgc gatggaaata tactcttttt gtgtaaattc gttaaagctt
     7201 tgattacctt gtagtagaaa gaagcggagt atttttaaaa tagttgattg gttataaagc
     7261 tgatggaagt aataattcgt ttgatgagaa tggtgttcga ttaattgaac ttgttgcgta
     7321 tctaaattaa atgtcaactc ttcctcgaat gtttcttgta attcctgcaa aatgcttagg
     7381 agacttttag attgtaatga agttaaagta gacagttcat ctagttcaat agaccgaata
     7441 tccaataata tatttaaaat ggtaatttta tctgtaattc ttttttcaat gtatttgttt
     7501 agcatagtta ccgaatctta gttgcatata gataatttta attattataa tacaaaagaa
     7561 actaattgtc ttgtcaaaaa ggttgtggaa tttccgactt tat
//
LOCUS       DAVLGK010000073         6784 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLGK010000073 DAVLGK010000000
VERSION     DAVLGK010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6784
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.074"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            402..1262
                     /gene="speE"
                     /locus_tag="VXE01_002062"
     CDS             402..1262
                     /gene="speE"
                     /locus_tag="VXE01_002062"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV0750909.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            1259..2518
                     /locus_tag="VXE01_002063"
     CDS             1259..2518
                     /locus_tag="VXE01_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV0750910.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            2518..3645
                     /gene="nspC"
                     /locus_tag="VXE01_002064"
     CDS             2518..3645
                     /gene="nspC"
                     /locus_tag="VXE01_002064"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV0750911.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            3642..4727
                     /gene="aguA"
                     /locus_tag="VXE01_002065"
     CDS             3642..4727
                     /gene="aguA"
                     /locus_tag="VXE01_002065"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV0750912.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            4737..5612
                     /gene="aguB"
                     /locus_tag="VXE01_002066"
     CDS             4737..5612
                     /gene="aguB"
                     /locus_tag="VXE01_002066"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV0750913.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(5793..6602)
                     /locus_tag="VXE01_002067"
     CDS             complement(5793..6602)
                     /locus_tag="VXE01_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0750914.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
BASE COUNT         1988 a         1342 c         1516 g         1938 t
ORIGIN      
        1 gttgagctgt cgaaaagaca gatctaagag ttcaaaacca gctttattat ttgaaaaagt
       61 gagtggttta agaacagttt tcctcgaaca ttcaaggctg taacatcgtg tttattttta
      121 gcgacatcaa tacctacata aagcatggga gtacctccag atatagtatt tcaagtctac
      181 ttggttatcc acgaactttt tgccttgtta ccttagacga gataaaacgt ctatgcgtta
      241 tcaaactcat taccaattga aacaaaaagc tgtggttaga gcctttcgga aatcgttaag
      301 cgattggagg aaatgaacta atccacagtg acttattcca agtataccac ttgggctttg
      361 gcagtagcta actgcgctaa atataatata aggagaaata gatggattta tggttttctg
      421 aagttcatac tccagatgtc aaattgtctc tgagaacagc caagcaactt tacgctggaa
      481 aaagtgaatg gcaggatatc gaagtcttgg atacgccagc ttttgggaaa atactgattt
      541 taaatggcca tgtcttgttc tcagatgcgg atgatttcgt ctacaatgaa atgaccgtcc
      601 acgttcccat ggctgtccac ccaaatccaa agaaagtatt ggttattggg ggtggtgacg
      661 gcggtgttgc ccaagtatta acactctatc ctgaactgga acaaatcgat atcgtggaac
      721 cggatgagat gttggtcgag gtctgtcgtg agtatttccc agactttgct gcagggctag
      781 atgatcctcg tgttaccatt tactaccaaa atgggctacg ctttttgcga aactgcgaag
      841 atgattacga tattatcatc aacgatgcga cagatccatt tggccatacg gaaggactct
      901 ttaccaagga attctacggc aatagttatc gagctctgaa ggaagacggc atcatgattt
      961 accagcatgg gagtcccttc tttgacgagg atgagtcggc ctgccgaagc atgcaccgca
     1021 aggtcaatca agcctttcca atcagtcggg tttatcaggc ccatattcca actagcccag
     1081 ctggctattg gttgtttgga tttgcatcga aaaaatacca ccctgtcaaa gattttgaca
     1141 aggaaggctg gaaaaaacgc cagcttttca cagaatacta cactgcaaac ttacacgtgg
     1201 gagcctttat gttgcccaag tatgttgagg acattttaga agaagaggaa ggaaaaaaat
     1261 gagtcgttta ctagttattg gttgtggggg cgttgcccaa gttgctattt caaagatttg
     1321 tcaagatagc gaaacattta cagagattat gattgctagc cgtaccaagt caaaatgcga
     1381 tgacttgaaa gcgaagctag aaggcaaaac aagtactaaa attgaaactg cagcacttga
     1441 tgctgacaag gtagaagagg tcattacctt gattgaaagc tacaaaccag aagctgtttt
     1501 gaatgtagct ctgccttatc aagatttaac cattatggat gcttgtttgg caacaggtgt
     1561 tcactatatc gatacagcca actacgaagc agaagacaca gaagaccctg agtggcgtgc
     1621 tatctacgaa aaacgttgta aggaacttgg ttttacagcc tactttgact actcatggca
     1681 gtgggcttat caagagaaat tcaaagaagc aggcttgact gctcttcttg gttctggttt
     1741 tgacccaggt gtaaccagtg tcttttcagc ttatgccctc aaacactatt ttgatgaaat
     1801 ccattatatc gacattttag actgtaatgg cggtgaccac ggttatccat ttgcaaccaa
     1861 cttcaaccca gaaattaatc tccgtgaggt ttctgcgcca ggttcttact gggaagatgg
     1921 gaaatgggtc gaagtcgaag ctatgtctat caagcgtgag tatgatttcc ctcaagttgg
     1981 acaaaaagat atgtatctcc ttcaccatga agaaatcgaa tcattggcca agaacattcc
     2041 aggtgtcaaa cgcattcgtt tctttatgac ttttggtcaa tcttacttga cgcacatgaa
     2101 atgtcttgaa aatgttggac tccttcgtac ggataccatt aactttaacg gccaagaaat
     2161 tgttccaatt caatttttga aagccttgct tccagatcct gctagccttg gcccacgtac
     2221 tgtaggtaaa accaatattg gatgtatctt tacaggtgtc aaagatggcg ttgaaaagac
     2281 tatctacatc tacaatgttt gcgaccatca agagtgctat gcagaagtcg ggtcacaagc
     2341 aatttcatac acgacaggcg ttccagccat gattgggaca aaattagtca tgaacggaac
     2401 ttggaaacaa gctggagtgt ataaccttga ggagttagat ccagatccat tcatggaagc
     2461 tttgaatgag tatggtttgc catgggttgt ggttgaaaat ccacaaatgg tggactaatg
     2521 aagttagaac aagtaccaac accagcctat gttattgact tggccaagtt agaagctaat
     2581 tgccgcattc tacaatatgt acaagaagag gccggttgca aggtcttgct tgcccagaag
     2641 gcatattccc tctacaaaac ttatcccttg attagccagt atctatcagg tacgacagct
     2701 agtggactct atgaggccaa attggcaagg gaagaatttc ctggtgaagt ccatgttttt
     2761 gcaccagctt tcaaggatga ggacatggag gaattgcttg ggataacaga ccatatcgtc
     2821 tttaactcag agagacagtt gcgtaagcat ggggctcgtt gtcgagaggc tggtgtcagt
     2881 gttggtttgc gcctcaaccc tcagtgttca actcaaggag atcacgcgct ctatgaccct
     2941 tgtgcacctg gttctcgctt tggagttact atagacaaga ttccgagtga tttgctagat
     3001 ttggttgacg gacttcattt tcataccctt tgcgagcagg gagcagatga tttacaaaca
     3061 actttgaaag cagtagaaga acagtttggt ccctacttac atgaggtaaa atggctcaat
     3121 atgggtggtg gtcatcatat tacaagagaa ggttacgatg tggatttgct gatttcagaa
     3181 atcaagcgta tccgaaaaac ttacaatctt gaaatctata tcgagcctgg tgaagccatt
     3241 gcgcttaatg cgggttattt agcaactgag gtattagata ttgtagaaaa cggtatggaa
     3301 atcttggttt tagacgcctc tgcgacctgc catatgcctg atgtacttga gatgccctat
     3361 cgtccacctt tgagaaatgg ctttgagtca caggaaaaag cccataccta cagactttct
     3421 tctaatacct gtctgactgg cgatgtgatt ggtgattata gttttgaaaa tccagtccaa
     3481 atcggagaca gactttattt tcaagacatg gccatttatt cttttgtcaa aaataatacc
     3541 tttaatggta ttggattgcc aagtctctat ctcatggacg aacagggaga ctgtagctta
     3601 ctcaaagctt ttggctatca agactttaaa gggagattat catgatggac agtccaaaaa
     3661 aattaggcta tcacatgcca gcagagtacg aaccccatca tggtaccctc atgatatggc
     3721 cgactcgacc aggatcatgg ccttttcaag gaaaggctgc taaaagagca tttactcaga
     3781 tcatcgagac catagcagaa ggggaaagag tctatctttt ggtggagcag gcctatctat
     3841 ctgaagccca atcctatctt ggagacaagg ttgtttattt agacattccc accaatgatg
     3901 cctgggcgcg tgatactggc ccaaccattc tcgtcaatga taaaggtaag aaattagccg
     3961 tggattgggc ctttaatgct tggggaggca cctatgatgg tctttatcaa gattatgaag
     4021 aggatgacca agtagccagt cgttttgctg aggccttgga aaggcctgtc tatgatgcta
     4081 aaccttttgt actggaagga ggcgcaatcc atagcgatgg tcaaggaact attctcgtaa
     4141 ctgaaagttg cttgcttagt cctggtcgca atcctaactt gactaaagag gagattgaaa
     4201 acacattatt agaaagtctt ggtgctgaaa aagttatttg gcttccttat ggtatttatc
     4261 aggatgaaac caatgaacac gtcgataatg ttgttgcctt tgttggtcct gctgaggttg
     4321 ttttggcttg gacagatgac gaaaatgatc cccagtatgc catgtcaaaa gcagatctcg
     4381 aactcttaga acaggaaaca gatgcaaaag gttgtcactt caccattcat aaattgccta
     4441 tccctgcagt tcgacaagtt gtgacagaag aagatttgcc aggctacatc tatgaagaag
     4501 gagaagaaga gcgatacgca ggtgaacgac tagcagcttc ctacgtaaac ttttatatcg
     4561 ccaacaaggc tgtcttggtt ccacagtttg aggatgtaaa cgaccaagtg gccttagata
     4621 tcctcagcaa gtgtttccca gaccgtaaag ttgtcggaat accagccaga gatattctct
     4681 taggtggtgg caatatccac tgtatcaccc aacaaattcc agaataggag aaaaagatga
     4741 gaaatgtaag agttgcaacc attcagatgc aatgcgctaa ggatgtggca acaaatatcc
     4801 aaaccgcaga gcgtttagta cgtcaggctg ctgagcaagg agcccaaatt attctcttgc
     4861 ccgagttgtt tgaacatccc tatttctgtc aggaacgtca gtatgactac taccagtatg
     4921 cccaatctgt agcggaaaat actgccattc agcattttaa ggtgattgct aaggaactac
     4981 aagttgtttt accaatcagt ttctatgaaa aagatggtaa tgtcttgtat aactctattg
     5041 ccgtcattga tgcagatggg gaagtgctgg gcgtttatcg aaagacccat ataccagatg
     5101 accattatta tcaagaaaaa ttctatttca cgcctggtaa cactggtttc aaggtctgga
     5161 atactcgcta tgctaagatt ggtatcggta tctgttggga tcaatggttc cctgaaacag
     5221 cgcgctgtct tgcattgaat ggtgctgaat tgctctttta tcctacagct atcggttcag
     5281 agccaatttt ggatacagat agttgtggtc actggcaacg tactatgcaa gggcacgcag
     5341 cagcgaatat tgttccagtc atcgcagcca atcgttatgg tttagaggag gttactccta
     5401 gtgaggaaaa tggcggacag agttccagtc ttgacttcta cggttcctcc tttatgacgg
     5461 atgaaacagg agctattcta gaacgagctg aaagacaaga agaagctgtt ctgttagcta
     5521 cttataacct agacaaggga gcaagtgaac gcctaaactg gggcttgttt cgagatagaa
     5581 gaccagaaat gtatagacaa attacagatt agtgtgggag aaatgagaga ttcattctgc
     5641 tagactaact tcttattagc aactataaga tactatggca tctagtaaat cgatttttat
     5701 gattcgctat tcttctctat tgattagtcc gtattttaaa atattagcaa aaaagcaaat
     5761 agcagtaact tctgtctatt tgcttttctt ttttatagaa tatatttctc aatagcacgc
     5821 gcaacgccgt cttcttcgtt gcttgaggta acggcatccg caagagattt gacataatcg
     5881 ctggcatttc ccattgcaat cccaagccct gcaaactgga gcatttcgat atcgttatta
     5941 gcatcgccca tggccataat ctctgaggaa tcaatcttca aaatctcagc tagtcgtgaa
     6001 agagcagtag cctttgtcgt tccaagtggc attgcttcat aaatgacagg ctgcgaacga
     6061 actccactga atcgttggca aagctcttca gcaaaacgct gctcaaaatc gtctgtttgt
     6121 tcttttgttc ctaaaaacat accttggaac atccggaact ttccactagt cgcttcctca
     6181 agagaaattt cagtcaggtc tgaaaatact agtttagcat cattttcaat aacttgattg
     6241 ggctttccac cgagaacaaa ataatgtgac tcgtcaaaaa gtgtcaactg aacatcactc
     6301 ttttcagcaa ggtcatagag gtattcgatg tcagctggac taagttcttg ccagtcaacc
     6361 aagccccagt cgctagtctg gtgagttgaa caaccgttgt taacaatcac atactcattc
     6421 tggaggtcga gtcccagttt tttgtagtag gggaggacac cgaaaagggg gcgacccgta
     6481 cagagaacca gtttgacacc tttttcaatg gctttgtgaa tagcagtaat gtgagcttgt
     6541 gggatttcct tggcttcatt gaggagggtg ccgtccatat ccaaggctag tagtttaatc
     6601 ataggtcttc cttctttatc ttttgctatt attatagcat attttggaga agaaattgat
     6661 agaaagcttg agactaattg attttatagt ttaagatgtt ttgatgacaa ttcatgattt
     6721 gaagaggata tttggcaaag atatgctata ctatgtttgt caatgttgca actagacaaa
     6781 ttaa
//
LOCUS       DAVLGK010000074         6485 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLGK010000074 DAVLGK010000000
VERSION     DAVLGK010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.075"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            121..648
                     /locus_tag="VXE01_002068"
     CDS             121..648
                     /locus_tag="VXE01_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0750915.1"
                     /translation="MEDYCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNT
                     RKAQGRHLEQEGNIKHALIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQ
                     TLMESLSDDDYDFAFDEALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKY
                     ECYSPLNNLELDDFE"
     gene            complement(820..891)
                     /locus_tag="VXE01_002069"
     tRNA            complement(820..891)
                     /locus_tag="VXE01_002069"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(856..858),aa:Arg,seq:cct)
     gene            complement(934..1281)
                     /gene="rplS"
                     /locus_tag="VXE01_002070"
     CDS             complement(934..1281)
                     /gene="rplS"
                     /locus_tag="VXE01_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV0750916.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(1400..1729)
                     /gene="crcB"
                     /locus_tag="VXE01_002071"
     CDS             complement(1400..1729)
                     /gene="crcB"
                     /locus_tag="VXE01_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0750917.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1723..2097)
                     /gene="crcB"
                     /locus_tag="VXE01_002072"
     CDS             complement(1723..2097)
                     /gene="crcB"
                     /locus_tag="VXE01_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0750918.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(2094..2360)
                     /locus_tag="VXE01_002073"
     CDS             complement(2094..2360)
                     /locus_tag="VXE01_002073"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV0750919.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(2476..2919)
                     /locus_tag="VXE01_002074"
     CDS             complement(2476..2919)
                     /locus_tag="VXE01_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV0750920.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            3023..3958
                     /locus_tag="VXE01_002075"
     CDS             3023..3958
                     /locus_tag="VXE01_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV0750921.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            4012..4296
                     /locus_tag="VXE01_002076"
     CDS             4012..4296
                     /locus_tag="VXE01_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV0750922.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(4353..4931)
                     /locus_tag="VXE01_002077"
     CDS             complement(4353..4931)
                     /locus_tag="VXE01_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEV0750923.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSTAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(4906..5919)
                     /gene="efeB"
                     /locus_tag="VXE01_002078"
                     /pseudo
     CDS             complement(4906..5919)
                     /gene="efeB"
                     /locus_tag="VXE01_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002909774.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
     gene            complement(5922..6473)
                     /locus_tag="VXE01_002079"
                     /pseudo
     CDS             complement(5922..6473)
                     /locus_tag="VXE01_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT         2037 a         1393 c         1132 g         1923 t
ORIGIN      
        1 aataatgtta acattgacaa tttagatatt ccgttcgaat ttaaactaac aaaagaagca
       61 caaaatctta ttatcgaaca tagtgactat atcaaagcat actatgataa agacataact
      121 atggaagatt attgtaaaga aaaaaacaat atctctttta aagcaacttt tggtgatata
      181 aaatggagtc tcttaaataa acaagctcat aggaatactg tatcaggaga ttttggatgc
      241 ttatctaaca cacgaaaggc tcagggaaga catttggaac aagaaggtaa tattaaacat
      301 gctttaatat attacataga atctttgata attactattt caggattaga aaacaatttt
      361 tcagccactg attatccagt atattatccc gattcgatac ctgactactc actaaaacat
      421 attcaaacat taatggaatc attatctgat gacgattatg attttgcttt tgatgaagca
      481 ttatttcgct tctcaatttt gaatgcaaat cattttttat ctaaggaaga tattgactat
      541 ttaagagtta atttacctcg ttccactgct gaagaaataa acaattactt aaagaaatat
      601 gaatgttata gtcctttaaa taatttagaa cttgacgatt ttgaataaat tgactataca
      661 aacatttata tactcgatat agtctcaatt ttatctgata attgcccaaa tttttcaata
      721 ataaaacgca taatattatg gagacacaca aaatcaccta tattatgcgt tcttttaata
      781 tcaaagactt tttgacaaac ttctttgatg tctaattact gccccctgca ggaatcgaac
      841 ctgcaactac tccttaggag ggagttgtta tatccattga actaagggag ctagataaaa
      901 actctgctaa atgagcagag ttttttagtc gaattaacga cggatttctt tgatacgagc
      961 tgctttacct tgaagagcac gcaagtagta caatttcgca cgacgtactt taccgtaacg
     1021 aacaacttcg attttttcaa cacgtggagt gtggattggg aagatacgct caacacctac
     1081 accgttagag attttacgaa ctgtgtagtt ttctgagatt ccagcacctt tacgtgcgat
     1141 aacaacacct tcaaaaatct ggatacgttc acggttacct tcgacaactt tcgcatgtac
     1201 acgaacagtg tcaccaggac ggaatgatgg gatatctgta cgaagttgac cttcagtcaa
     1261 gctttggatt aatggattca ttttattctc ctatctttgt caatcttgag gaatcttcct
     1321 cagcggataa actgtatttt tgtgcgtcca ttacacacaa gatatagttt accaaatttc
     1381 taaaaaaaag taaagaaatt tatagcaaaa ttcctaaaaa aatcgcaacc aaaccaccta
     1441 tgtaagtcaa agtcaggtaa gaataaaaga ccttcttatc acttagcagt ctttgaagtt
     1501 cgtcattcaa ggtcgaaaaa gttgttaaac cgccacaaaa tcctgttgct agaatagcat
     1561 atacttcctt agactctaca tgattgtaga atactccaat taaaaaacaa cctaaaagat
     1621 tagctatgag cgttccaagt ggcaatttag aagcttgatt gtagcgggaa aagaaatacc
     1681 gtacgagtgc tccgaaacca caagcaattg caagatagac gattaccatt tcttcctccc
     1741 tagaaaataa gctaagagta ggcctccacc gatgctcaaa agcaaataca ggactaaact
     1801 aagataacgc cctgtatcaa gcagcttcac agtatcaagc attaggctgg aaaaagttgt
     1861 taaacctccg caaaaacccg tccccagtgc taaaatcaag cccttactag tccccttata
     1921 gaccagatag cccttgacaa gaaaaatcaa gcagaaaatt cccagatagt tgacaaagag
     1981 agtgccccaa ggaaagtctg gactggctgg taaccaggtg gaaactagat atcggacaag
     2041 tccgcccaac atagcagcta gaaaaattcc tagcggataa aattgttctt ttttcatttg
     2101 atattttgat cctgataatc acgcgaacgt ttgagtatgt ccgaaaaagt cgcgacaata
     2161 gtctcctgat agcgcttgtc ctctacacga ctcctaacct tttcaaaaat aacttcttct
     2221 ctcttagtat ctaaaatcgg tttacctgaa gctttcttat aagcaaccac cccctcaact
     2281 aaatgcattc gttcttctaa cagtttgaca atttggtcgt cgatttgatc gatttcttga
     2341 cgaataatat ctaaatccat acagtctcct cctttatttg aattattgta tcaaaaagcc
     2401 atcaattagg ctagtaaaat cccaactctc gataagaaaa atgcactgat tgattacatc
     2461 agcgcacttt tatgtttatc ctactttagc agccaattct tctgcgaatt gttccaagcg
     2521 ttcaatatct tcttcctcgg cagaaagatc aactttaaca cactctgaac ctttttctgc
     2581 tcctgttgac acaaagacac ggtcaaagtc atcaacagcc ttacagaatt catcgtagaa
     2641 ggtatctcct gagccgacca ctccgtagat tttgccattc aagttgagat ctgctaggtc
     2701 ttcgtagaag tccatcatct catctggcaa ttcaccatca ccataagtat aggtcgcaac
     2761 gatagcgatg tctgcttcca agaagtctga agcgtcaaca gttgtacatt catcaacatc
     2821 aacatccaag cccaagtcac gtaatttgtc tgctacaata tctgcaattt cttcggtatt
     2881 accggtcata ctggcaaata caatttttgc taatgccata tcgtcctcct caatttatct
     2941 ttctccatta tatcacatct ttttcatttt aaaaataaaa attcttgtgc tacaatgaaa
     3001 tgagaaagaa ttgaggttat ttatggagat ttgccaacaa attttagaaa aaattaaaga
     3061 atacgacacc attatcattc atcgtcatat gaaaccagac cctgatgcct tgggaagtca
     3121 ggtgggattg aaagccttgc tggaacatca tttcccagaa aaaaccatca aagccgtcgg
     3181 ttttgatgaa ccaactctta cttggatggc tgagatggat cttgttgaag atagagccta
     3241 ccaaggcgca cttgtcatcg tctgtgatac agctaatact gctcgtatcg atgataagcg
     3301 ctatagtcaa ggtgattttc tcattaagat tgaccaccat ccaaatgatg atgtatacgg
     3361 tgacctgtct tgggtcgata ctagttcaag tagcgctagc gagatgatta ccctatttgc
     3421 ccaaacaacc caactagcct tggcagatcg cgatgctgag ttgctctttg caggaattgt
     3481 cggtgataca ggtcgcttcc tctacccttc taccactgca cggactcttc gcctggctgc
     3541 ttatttgaga gaacataact ttgactttgc ggctctcact cgcaaaatgg acactatgag
     3601 ctacaaaatt gctaaactgc aaggctacat ctacgaccat ctggaagtgg atgaaaatgg
     3661 tgctgctcgc gttatcctga gtcaagaagt cttgaaacaa tacaatgtaa ccgatgctga
     3721 aactgcagcc attgtcggtg cacctggacg cattgacaga gtgagtctct ggggaatttt
     3781 tgtcgaacag gctgatggcc actaccgcgt tcgcttacgc agtaaaatcc atcctatcaa
     3841 tgaaatcgcc aaggagcatg atggtggagg ccaccctcta gcaagtggtg ctaattccta
     3901 tagcctagaa gaaaacgaaa tcatctacca aaagttaaaa aacttgctta aaaactgata
     3961 aaatacttgc caaacttttc agaatctgat agactagtat ggtaacaatc tatggctcgc
     4021 aaagagacca tggcagaaag gaaatattgc aaaatgaaaa aagatatcca tccagaatat
     4081 cgcccagttg tcttcatgga tacaactact ggttaccaat tccttagcgg ttcaacaaaa
     4141 cgctctaacg aaacagttga gttcgaaggc gaaacttacc cattgatccg tgtggaaatt
     4201 tcatcagact cacacccatt ctacactgga cgtcaaaagt tcactcaagc agatggacgc
     4261 gtggatcgtt tcaacaaaaa atacggtctc aaataatgat aagagaacag tttcggctgt
     4321 tcttttttgt ttcttgaaat caactgctgt tttcatgttc cagactcatc tgtaggttcg
     4381 gtttccatgc tactaggcag gaaggaaata gctgtttcaa cacgtccata atgagctgta
     4441 ctattgtcac gaaccacact ttcattgatg gtccaagtgg aattcatttt cttaaaagct
     4501 tctcggactt tttccaaatc tttggaggca atggcctgtt ctaaggtttc aaaacgagga
     4561 cttagacggt ttaccaattt ttccttttcc gcatctaggt caacaggatt ttgttctttt
     4621 tcaaaagcta atagagctga ggaaatttcg gtgagtttgg cttcagtaat atctccagat
     4681 agagctaact tttccttaac aatcttacca acctcagaat ccttattttc tactctttcg
     4741 aagtctgatg ccatcttcgt aacgagtttc tgggtctcag tctgaccacc atttttaacc
     4801 gttttggatg catctgtgat tttcacaaag aaaaaactca agctttcttg ggcacctgct
     4861 ggggaaagaa ttaaaaatga caaagctaaa actagtaacc agcttttagc cttccaataa
     4921 tttctgacca atgtagcctc ctttctccac accaccaaag caagtaaaaa gtccactacc
     4981 tatgtgagtg atgtattcat tcatcttatc agtagcacct aggttagttt gaaccttaac
     5041 aaagttatca ggatccttct ggaaagaaat gaagagcaat cccgtatcaa actgaccagt
     5101 cttttcatca atgccatctg agtaagaata agaacgacgt aaaagtggct tatccacttc
     5161 tttggccaaa caaacatgcg aatcatcagg taagagactc aaatccactt catcaaactc
     5221 atttttctta ccaaaggggg caccgctttc cttgtaacga ccaaaggtat tttcttgttc
     5281 ttcgagacta gtgcggtccc aggtctctaa aaacatctga atccgacgaa ctgccatata
     5341 agaaccattt tccatccagt ccttactatc agcccagata acgcggtcaa agtcttgctc
     5401 cttggttgga tttgctgttc catccttaaa accaaagagg ttccacggag tctccattcg
     5461 atccccgata gctgcaaatc cagactgact ccaacgaagg ggcaccgcat ttctcccctt
     5521 acggatgaga ttgcgaatag cgtgaaaggc aatttgctca tcatctgcac aagcatgaat
     5581 cacaatatct ccaccagtat atttttcacg taattgctcc ttaggaaata gaggtaaatc
     5641 cctgaacagt cgagggcgct tgttttccaa gttcatcctt ttcaagaaac ttgcagatac
     5701 accaaaagtc agcgtcaaac gatgaggatt gagcccaact gtctcaccag tatcgctcgg
     5761 aggaaagaga gcattctgtc catctttttt aaccaattcc ccctcgacca acttggcact
     5821 ataatccgtc caatccttga atagctggat aattttatct ctatccgtcg tatgcaggtc
     5881 caagacaaca aaatagatat tcttttgcat gggcgtacta tttggtacat caagcgaacc
     5941 ttatgaaaac gtctactata tttaaaacgc tttcttgtct tcttgaattg agattttatt
     6001 tttagacgcg acaatggttt gagcgtctgc tttcttagga tgttctggac gtggcataat
     6061 atttcgccaa ccatggcgct tcaacagttg atagaaggca tcacgtgtgt aggaacgacc
     6121 taactccttt ttataagcct gaaataaggc atcaattgta acaaattctc ctgcctctgc
     6181 agccttcaaa tggcgggcaa gaaagacttt cttttcctca actgtcatat atgcatggtt
     6241 acgaccacta cgtgtttctt gaaggagaga gtcgagtccg aactcctcat atttttttac
     6301 attttgctaa atcgttgttt gattacagtc taaaagctct ataatctctt tataagattt
     6361 gcccatcaga cgaaatataa taaattgaaa ctagaatagt acacctctac ttctaaaaca
     6421 ttgttagaaa tcgatttgac tgtcctaatc gatttgtcct gttcttgttt cattttacta
     6481 tagaa
//
LOCUS       DAVLGK010000075         6437 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLGK010000075 DAVLGK010000000
VERSION     DAVLGK010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6437
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.076"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            1..296
                     /locus_tag="VXE01_002080"
                     /pseudo
     CDS             1..296
                     /locus_tag="VXE01_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            463..663
                     /locus_tag="VXE01_002081"
     CDS             463..663
                     /locus_tag="VXE01_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750924.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATISDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            705..1109
                     /locus_tag="VXE01_002082"
     CDS             705..1109
                     /locus_tag="VXE01_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750925.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1340..2047
                     /gene="ccdA2"
                     /locus_tag="VXE01_002083"
     CDS             1340..2047
                     /gene="ccdA2"
                     /locus_tag="VXE01_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0750926.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2058..2615
                     /gene="sdbB"
                     /locus_tag="VXE01_002084"
     CDS             2058..2615
                     /gene="sdbB"
                     /locus_tag="VXE01_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV0750927.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKAITFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2989..4380
                     /locus_tag="VXE01_002085"
     CDS             2989..4380
                     /locus_tag="VXE01_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV0750928.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4523..5440
                     /gene="adcAII"
                     /locus_tag="VXE01_002086"
     CDS             4523..5440
                     /gene="adcAII"
                     /locus_tag="VXE01_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV0750929.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5448..>6437
                     /gene="phtD"
                     /locus_tag="VXE01_002087"
     CDS             5448..>6437
                     /gene="phtD"
                     /locus_tag="VXE01_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0750930.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELE"
BASE COUNT         1972 a         1165 c         1355 g         1945 t
ORIGIN      
        1 tagccttatt tcttaagaat tttaatagtt taaagcacct agcacctgtt tagattgacg
       61 aaacaggatt cgatacttat ttttatcgag aatatggtcg ctcattaaaa gatcagttaa
      121 taagaggcaa agtatctgga agaagatatc agaggatttc tttggttgca ggtctaacaa
      181 atggtgaatt aatcgctcca atgacttacg aagagatgat gacgagcgac ttttttgaag
      241 tatggtttca gaagtttttc ttaccaacat taaccacacc atcggttatt atagtaaaat
      301 gaaataagaa taggacaaat cgatcaggac agtaaaatcg aattctaaca atgttttaga
      361 agtccatatg tactattcta gtttcaatat accataactg ttcctagtca acctgcaagc
      421 cctgtcccag ctccaagctc agctccgact caagatccta gagtggtagc aagcgcttcg
      481 gctagctcaa cgagcacaca agctcaagag caagttgaca agtctgaact tcgtgccttg
      541 agtcaagagt tagaccaacg cttgaaagct ttggcaacaa tatctgatcc gaaaatcgat
      601 gcaaccaagg ctgtcctcct agatgctcaa aaagctccgg aagatagtgc cttgacagag
      661 taaggtctgc atactgcagt agagtctgtg aaggctgggc tgccttggac tctctcaaag
      721 atgtgaaagc aaatgctagc gacagcaagc ctgcacagga caagaaggat gcaaaacaag
      781 gaacggaaga tagtaaggat tcagataaga tgactgaaac aaactcagtt ccggcaggag
      841 tgattgtggt cagtctactt gccctcctag gcgtgattgc cttctggctg attcgccgta
      901 agaaagagtc agaaatccag caattaagca cggaattgat caaggttcta ggacagctag
      961 atgcagaaaa agcggataaa aaagtccttg ccaaagccca aaaccttctc caagaaaccc
     1021 ttgatttcgt gaaagaagaa aatggctcag cagagacaga aactaaacta gtagaggagc
     1081 ttaaagcaat ccttgacaaa ctcaagtaaa acatgattta tgaaatgtca gacctaaaag
     1141 acattttcgt tcacaaaagc agcgatgagt aatccttgtc gttgcttttt ggctattttg
     1201 ggggataaga tccgccttga ctagcaaaag aaaagattgg tccaatagtg cccgatacga
     1261 ttttgcgtag cagaaagctt acaaataaaa ttgaatatag taaaatagga ttagaattat
     1321 taagaaagtt ggttctttat tggaaacgat agtattttta atctctgttt ttctagcagg
     1381 tgttttatcc tttttttctc cttgtatttt tcctcttctg ccagtctatg ctgggatttt
     1441 attggatgat caagaaagtg caaaaagctt ttctttgttt gggagaaagg ttctctggtc
     1501 aggcttgatt cgaacacttt gctttatcgc tggtatctct ctcattttct ttattctagg
     1561 ctttggtgct ggttactttg gtcatattct ctatgcaaat tggtttcgat atggcatggg
     1621 agctattatt atcattttgg gtcttcacca gatggaaatt tttcatttga agaaattaga
     1681 agttcaaaaa agttttacct ttaaaaaatc agattctaat cgttattggt cagctttttt
     1741 acttggtatt acctttagct ttggttggac accttgtatt ggtccagttt taagttctgt
     1801 tttagcactt gcggcttctg gaggcaatgg cgcttggcaa ggagcgattt atactctcat
     1861 ttacactctg ggcatggccc ttcctttctt ggtattggca ctagcttcag gtctagtcat
     1921 gccatatttt agtaaaatca agcgtcatat gatgctacta aagaaaattg gtggtttcct
     1981 cattgtttta atgggaattt tgttactatt aggacaagta aatgttctag ctggaatttt
     2041 tgaataaagg aggacaaatg aaaaaagtaa tgtttgctgg cttaagtctc ttgtcattag
     2101 ttgtattgat ggcctgtggt gaggaagaaa ctaaaaagac tcaagcagca caacagccaa
     2161 aacaacaaac gactgtacaa caaattgctg ttggaaaaga tgctccagac ttcacattgc
     2221 aatccatgga tggcaaagaa gttaagttat ctgattttaa gggtaaaaag gtttacttga
     2281 agttttgggc ttcatggtgt ggtccatgca agaaaagtat gccagagttg atggaactag
     2341 cggcgaaacc agatcgtgat ttcgaaattc ttactgtcat tgcaccagga attcaaggtg
     2401 aaaaaactgt tgagcaattc ccacaatggt tccaggaaca aggatataag gatatcccag
     2461 ttctttatga taccaaagca atcaccttcc aagcttatca aattcgaagc attcctacag
     2521 aatatttaat tgatagccaa ggaaagattg gaaagattca atttggtgct atcagtaatg
     2581 cggatgcaga agcagcattt aaagaaatga actagaatcg ataaaatctg attacaagat
     2641 gtagtcagat tttggtaact tctaaaacta acttccagtt tcccacaacc tagcttttag
     2701 tatgagaaaa acgcgtgaca tcagtggaaa tccgtcttag actaacttcc actggttttc
     2761 tttttcttaa tatataaggg ttcaaaagcg aaaagactca gaaaaagtgc acgacaaata
     2821 gccctaaaac agagtcatct gagactaact tccagttttg ggagagagat ggaagttact
     2881 ttgagaagtt acggtagtca gattttttta gaaaaacatt ttataaatat tcacatatct
     2941 cctatattta tggtaaaata gaatcatcag tttattttgg agtcaaagat gaatatattt
     3001 agaacaaaga atgttagttt agataaaaca gagatgcata ggcatttgaa gttatgggat
     3061 ttgattttgc tgggtatcgg agccatggta gggacaggcg tctttacaat cacaggtact
     3121 gcagctgcaa cacttgctgg cccagcccta gtgatttcaa tcgttatttc tgccttgtgt
     3181 gtgggattat cagccctctt ttttgcagaa tttgcctcgc gagtacccgc tacaggaggt
     3241 gcctatagtt acctctatgc tatcttagga gaattccctg cctggttggc tggttggtta
     3301 accatgatgg agttcatgac agccatatca ggcgtagctt cgggttgggc agcttatttt
     3361 aaaggcttgc tctctcaata cgggatagcc tttcctcagg ctttaaatgg tacctttaat
     3421 cctcaagcag ggacatttgt tgatttattg cctattcttg tcttggtctt ggtgacttcg
     3481 cttgttttac taaatgccaa ggcagcctta cgctttaatt cgattctagt tattttgaaa
     3541 ttttccgctt tagctctctt tgttttagta ggaatttgga atattaagtt tgataattgg
     3601 agcaattttg ctccttacgg ttttggacaa atctatggag ctagcactgg tattatggct
     3661 ggtgcgtcct tgatgttctt cggttttttg ggatttgaat ccatctctat ggctgtagat
     3721 gaagtcaaga ctcctcaaaa aaatattcct agagggattg tcttatcgct ttctatcgta
     3781 accattctct atgccttggt gacccttgtt ttgactggtg tggttcacta tagtcattta
     3841 aatgtcgatg atgccgttgc ctttgccctt cgtagtgttg ggattagttg ggcagccaac
     3901 tatgtgtcat tagtggctat cttgaccttg attacagttt gtatttcgat gacctatgcc
     3961 ctatcgcgta tgatttacag tttagcacgt gacggcttag tgcctgctgc ctttaaggaa
     4021 ctgacgaaga ctagcaagat accaaagaat gctactatct tgacaggtct agcttcagca
     4081 gtagcagcag gaatgttccc actagccagt attgcagcct ttttaaatat ttgtacctta
     4141 gcctacttga tcatgttggc ttatggtctg attcgcttac ggaaagaaaa aggaatgccc
     4201 aaagctgggg aatttaaaac accattggta cctctgttac caattttatc gatcatcatt
     4261 tgtttatcct tcatgttaca gtataatatg aatacctgga ttgctttcct agttgcgttg
     4321 ttagtaggaa gtattattta cttcacttat ggctataagc attctaccat agaagaataa
     4381 agtgaaagtc tattgagttg ttgacactca gcagattttt atatgtgaaa gaaatttcaa
     4441 attttttcta aaaatatctt gacagattaa attttcagga gtagaatatt tactagttaa
     4501 ttaaatggtt aaggagttgt tcatgaagaa acaaaattta tttttagtcc tgttaagtgt
     4561 ctttcttttg tgcttggggg cttgtggtca aaaggaaagt cagacaggaa aggggatgaa
     4621 aattgtgacc agtttttatc ctatctacgc tatggttaag gaagtatctg gtgacttgaa
     4681 tgatgttcgg atgattcagt caagtagtgg tattcactcc tttgaacctt cggcaaatga
     4741 tatcgcagcc atctatgatg cagatgtctt tgtttaccat tctcatacac tcgaatcttg
     4801 ggcaggaagt ctggatccaa atctaaaaaa atccaaagtg aaggtcttag aggcttctga
     4861 gggaatgacc ttggaacgtg tccctggact agaggatgtg gaagcaggag atggagttga
     4921 tgaaaaaacg ctctatgacc ctcacacatg gctagatcct gaaaaagctg gagaagaagc
     4981 ccaaattatc gctgataaac tttcagaggt ggatagtgag cataaagaga cttatcaaaa
     5041 aaatgcgcaa gcctttatca aaaaagctca ggaattgact aagaaattcc aaccaaaatt
     5101 tgaaaaagcg actcagaaaa catttgtaac acaacataca gccttttctt atctagcgaa
     5161 gagatttggg cttaatcaac ttggtattgc aggtatctct cctgaacaag aaccaagtcc
     5221 acgacaacta acagaaattc aggaatttgt taagacctat aaggttaaaa cgatttttac
     5281 agaaagtaac gcttcttcaa aagtagctga aactcttgtc aaatcaacag gtgtgggtct
     5341 taaaactctg aatcctttag agtcagaccc acaaaatgac aagacctatt tagaaaatct
     5401 tgaagaaaat atgagtattc tagcagaaga attaaagtga ggaaagaatg aaaatcaata
     5461 aaaaatatct agcaggttca gtggcagtcc ttgccctaag tgtttgttcc tatgaacttg
     5521 gtcgtcacca agctggtcag gttaagaaag agtctaatcg agtttcttat atagatggtg
     5581 atcaggctgg tcaaaaggca gaaaatttga caccagatga agtcagtaag agagagggga
     5641 tcaacgccga acaaattgtt atcaagatta cggatcaagg ttatgtgacc tctcatggag
     5701 accattatca ttactataat ggcaaggttc cttatgatgc catcatcagt gaagaacttc
     5761 tcatgaaaga tccgaattat cagttgaagg attcagacat tgtcaatgaa atcaagggtg
     5821 gctatgtcat taaggtagac ggaaaatact atgtttacct taaagatgcg gcccatgcgg
     5881 acaatattcg gacaaaagaa gagattaaac gtcagaagca ggaacgcagt cataatcaca
     5941 actcaagagc agataatgct gttgctgcag ccagagccca aggacgttat acaacggatg
     6001 atgggtatat cttcaatgct tctgatatca ttgaagatac tggtgatgct tatatcgttc
     6061 ctcacggcga ccattaccat tacattccta agagtgattt gtctgccagt gaattagctg
     6121 ctgcccaagc ctattggaat gggaagcagg gatctcgtcc ttcttcaagt tctagtcata
     6181 atgcaaatcc agctcaacca agattgtcag agaaccacaa tctgactgtc actccaactt
     6241 atcatcaaaa tcaaggggaa aacatttcaa gccttttacg tgaattgtat gctaaaccct
     6301 tatcagaacg ccatgtagaa tctgatggcc ttgttttcga cccagcgcaa atcacaagtc
     6361 gaacagccag aggtgtagct gtccctcatg gtaaccatta ccactttatc ccttatgaac
     6421 aaatgtctga attggaa
//
LOCUS       DAVLGK010000076         6231 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLGK010000076 DAVLGK010000000
VERSION     DAVLGK010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6231
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.077"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(1..472)
                     /locus_tag="VXE01_002088"
                     /pseudo
     CDS             complement(1..472)
                     /locus_tag="VXE01_002088"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(505..843)
                     /locus_tag="VXE01_002089"
     CDS             complement(505..843)
                     /locus_tag="VXE01_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0750931.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADFISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEYYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKKLIK"
     gene            complement(856..1629)
                     /locus_tag="VXE01_002090"
     CDS             complement(856..1629)
                     /locus_tag="VXE01_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0750932.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(2075..2830)
                     /locus_tag="VXE01_002091"
                     /pseudo
     CDS             complement(2075..2830)
                     /locus_tag="VXE01_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(2968..4590)
                     /gene="groL"
                     /locus_tag="VXE01_002092"
     CDS             complement(2968..4590)
                     /gene="groL"
                     /locus_tag="VXE01_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV0750933.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(4606..4890)
                     /gene="groES"
                     /locus_tag="VXE01_002093"
     CDS             complement(4606..4890)
                     /gene="groES"
                     /locus_tag="VXE01_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV0750934.1"
                     /translation="MLKPLGDRVLLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(5046..5423)
                     /locus_tag="VXE01_002094"
     CDS             complement(5046..5423)
                     /locus_tag="VXE01_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0750935.1"
                     /translation="MIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGEREADFVN
                     MVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLLESRAQR
                     AMRENNAGQDLADLVLEEEELPF"
     gene            complement(5450..5692)
                     /locus_tag="VXE01_002095"
     CDS             complement(5450..5692)
                     /locus_tag="VXE01_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750936.1"
                     /translation="MKILNIKLANVEQTDSGFEHWVDVTYNVPILKNEYTVRLLLLFG
                     FEIEDPEVIEYLVNAWKYRELVLHSVRMYDMEREAS"
     gene            complement(5924..>6231)
                     /gene="lytA"
                     /locus_tag="VXE01_002096"
     CDS             complement(5924..>6231)
                     /gene="lytA"
                     /locus_tag="VXE01_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0750937.1"
                     /translation="DRWKKYTDGNWYWFDNSGEMATGWKKIAEKWYYFNEEGAMKTGW
                     VKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
BASE COUNT         1807 a         1328 c          999 g         2097 t
ORIGIN      
        1 catttaatcg tttttgaaaa tataaagcaa tacttttaga ttcaataaac tcaaaatatt
       61 ttatgacatt gtccatttgt ttaattccag attctttaga ttctgtcagg tatattttat
      121 atccttctac aaatttgaat gtagattttt caaaaacttt tgtgtcatct tttaataatt
      181 tttgtaattt catttcaaag tagtctgcat atattagatg tgaattttca aggcaacaga
      241 accaaaaatt taaacaagct gacacaacta aatttctatt cttgccgatt ttttcgtaat
      301 aatgtgtacg ttctagtatt tcttttccga ccatgtaaat ataatctgtt tcaaaaagat
      361 gatataaatt accaatcagc gttatctcat aggactccca tcgttccttc tggaataaat
      421 agtcatatac taaatttaga tcatctctac taactacatg attacaatct agctgatttc
      481 ataatccctg aaccataatt gtatttattt tatgagtttt ttcccactct tctcaaaaag
      541 tttttgttgc ttatttttta ttacctccaa tcctttaata ttcaaactat aaaaatttgg
      601 agataaatta accaaaaaat catcacgctc cgatctttta taatattcta agtgattaca
      661 aaaattctct atcgaaacat tgatatttga taataattca aaaaatgttg aaagagaaat
      721 ttcattttct cccctttcaa atctagaaag ttgagatttt gatataaaat cagctgcagc
      781 atactctaaa gaatatccgt ttaattttct aaaatatcga aaagcttctc cgtaattttt
      841 cacactttca ttcccttaac tttcttttcg agcgataaac ataccatatt ctttaggaat
      901 gatcaacata ccattattaa actcactttc caatctttta cgtattattt cctcttctag
      961 tgaacctatt tctgaaattc ctttaaacga ttggatgtat ttaactaggt catctatact
     1021 agttacctgt aactcatcat catagagtaa tgtatcgaca gagttaaaat acctactcag
     1081 gtacctttta ccattttgta aagtaaacgt tctattttct aaatcttgat taacctcatc
     1141 tttaaataaa cttgccaaat aatttacaac tccattttca ccaaatgtag cacagtaaaa
     1201 aatgcctccg gtttttaaga ccctattcac ctcagagaga gctttaggaa tatcattcac
     1261 atgatgtaga agcatattag caataacaat atcaaaagtt tcattctcaa aagaaatctt
     1321 ttgaatatcc attatctcat aattgacatt gtttctattt ccaatcactg acttcgttga
     1381 ttttaccata tctttagaaa aatctgtaac aatcaactgc ttcattttat ctatagaatc
     1441 actattactt ttccacaatt ctcctgtacc acatcccaat tctagaacct ttacttcatc
     1501 agtgatttgg tagttagaaa atatccaatt attaaatccc aatttatttt ttgaatactt
     1561 cttatgcaat tctactcgaa tatcaagatt atcatgactt ttatattgtt caattacttt
     1621 atcaatcatt ttaaatgacc tccactctat aatttggcat tatatcacaa gaataaagat
     1681 agtgttaaat aagttatata aatgcaaaaa aggaatattc cgttatagca gagttgtaac
     1741 acatttctat aaagaaattt attcctacga ctcagtttgg catgcttaac ttcctaactc
     1801 aaaaacaaag catcgattaa tttatccgtt cttcttttga aacagatttg aactgataat
     1861 tgctcgtttt aatttaaaaa gctcttttga gcaaaacttc atttttttaa gagtccaaca
     1921 atttctgtct atcgcttttc tactagcaaa aaacctacct tgaggcaagt tttcatttat
     1981 atatctaatt tcgtaacagt atagtaaaat gaaataagga cagtcaaatc gatttctaac
     2041 aatgttttag aagtaaaggt gtactattct agtttcaatc tactataaat ttgatatgag
     2101 aatagtcttt ctcaacatcc ttatccaaca agcatgctgt ggcgtccttc ttaacttaaa
     2161 ccaggtcaat attctgggct tgggctgcat agacgcagcc acaataacat tgacgataga
     2221 tatcatactc ctcacacatc tctactgaac gtttgtagcc ttgatttttc ttgaaatcgt
     2281 tgggaaaata gtggggcgtg taaatttttt gcacatcgat tccgatgcta ttgatagttt
     2341 gagaattctt atgaggactg atggtcaagg ctgaaccaaa gtagtcaaag cccaagtcca
     2401 tagccacttg cgctgtttta tccagtcggt agtcaaaaca aaccttgcaa cggtcgccac
     2461 cttcgggctc ctcctctagc cccctaacta gttttcggta ttaattgggt tcgtagggag
     2521 cttctaggta ctgaaccgta tttcctgtcc gctcattaaa atcactaaca aatttcttgg
     2581 tgacatagac ccgcttatgg tattctgcct tgggatggat attagaattg gcaaaataga
     2641 tggtcacatc tgcatacttg gtcaaatatt ctagtgtata ggtactacaa ggggcacagc
     2701 aaacatgcac gagaatggtt ggccgctact catttttttc ccatgcttgt accattttct
     2761 gcatgacacg gtcataatta atcttctgat tgggggtcat cttgcacaga atttcttcta
     2821 catcgatcat gttcttctcc tttttctagt cttattttat catataagtt aggagagctc
     2881 aaatcaattt agaagtgaat attataaaaa gaagggttag tcattccctc cttttgtgtt
     2941 ttttataagt tgttttctat agaaagctta catcatcccg cccatcatac ttggatccat
     3001 tgctggagct ggggctactg gttctggttt attggctacg actgcttctg ttgtcaaaat
     3061 caagctggct acagatgctg cattttgtag ggctgaacga ctcactttaa ctggatcaat
     3121 gataccttga tcaatcatgt taacccactc gccagttgct gcgttgaatc ctataccaag
     3181 ctcagcattt ttcaaacgat cgataacgat agatccttca aatcctgcat tgtgagcaat
     3241 ttgacgaacg ggttcttcca aagcacggag aacaatatta cgtcctgttg cttcatctcc
     3301 tgtcaattcc aaggtagcaa cagctggaat cacattggca agagctgttc caccacctgc
     3361 aacaatacct tcttcaacag ctgcacgagt agcgttgagg gcatcttcaa tgcggagttt
     3421 catttctttc aactcagttt cagttgcggc tccgacctta ataaccgcta caccacctga
     3481 caatttggcc aagcgttctt gcaatttttc acggtcaaat tcagaagttg tagtttcgat
     3541 ttgagacttg ataaccgcaa cacggtgaga aatcgcttca ggatttcctg caccttctac
     3601 aataaccgtg ctatctttgt ccacggtcac tctcgctgct tgaccaagag cttcaattgt
     3661 cgcatctttc aactcaagac caaggtcttc tgtgataact gttccgcctg ttaagatggc
     3721 gatatcttca agcatggctt tgcgacggtc accaaaacca ggtgccttga ctgctactac
     3781 gttgaaggtt ccacgaatct tgttcaaaac aagagttgga agagcctcac catccacatc
     3841 atccgcaata atcaagagtg gacgattgct ttggagaatg ctttccaaaa gtggcaagat
     3901 ttcttggata ttggaaattt tcttgtctgt aatcaaaatg tacggatttt caaggtcagc
     3961 caccattttt tcgctatctg tcaccatgta ctgtgaaagg taaccacggt caaactgcat
     4021 tccttctacg acttcaagct ctgtttccat accacgtgac tcttcgatgg tgatgacacc
     4081 gtctttgcca actttttcca ttgcttcaga gatgtactca ccaacttttt cagaacgaga
     4141 agatactgct gcaacttgag cgatagcttc tttattggca acagggatgg cgttgttttt
     4201 caaagcttca actgctgcgg caactgctgt ttcaatccca cgacgaatac cgattggatt
     4261 tgcacctgct gtgacgtttt tgattccttc acggacgata gcttgggtca agactgttgc
     4321 agtcgtagtt ccgtcacctg cgatatcatt ggttttagaa gctacttctg atactaactt
     4381 agcacccata ttttcaaaat ggtcttccaa ttcgatttct ttggcaatgg tcacaccgtc
     4441 attggtaatc aagggtgaac cgaatgactt ttcaagaacg acattgcgac cttttggtcc
     4501 caaggttact ttaacagtgt ctgcaagaat atcgacacca cgaaccatgg ctgaacgggc
     4561 atctgatgaa aatttaattt cttttgacat acttactttc tccttctatt cctcaatgat
     4621 tgccaaaatg ttagcttcgc ctacgatgat gtacttttca tcgccatctt tgacatcaag
     4681 acctgcgtgg gcttcaacta agacacgatc tccagtttta acacttggag caaccaagtc
     4741 accgttcaag gtacgaacac cttgtccagt agccacaact tgagctgttt tggttttttc
     4801 ttgggctgag cctgcaagga caaagccccc aacggtttgt tctttttctt ctatttttaa
     4861 gagcacacgg tcccctaatg gtttcaacat ctgatttcct ccataatgag atagatatta
     4921 ttagcactct ttgaactgga gtgctaattc ataattctat tgtatcactt ggtcagaaat
     4981 agtcaagaaa aaagtctgac tttctcaaga taaaaagcct gagaccaact cagacttttt
     5041 aattcttaaa atggcaattc ttcctcttcc aagaccaaat ctgccaaatc ttggcctgca
     5101 ttattttcac gcatagcacg ttgggcacga ctttccaaga gttggaatcc tgtcacaagg
     5161 acttcggtta cataattcat ctgaccattt ttctcaaagc gacgggtacg caattctcca
     5221 tcaacggaaa tgagactacc tttggttgcg tagcttgcca aagtttctgc tagtctgccc
     5281 catagaacca tattgacaaa atcagcttca cgttcaccgt tttggtcttt gtaacgacgg
     5341 ttgacagcga tagttgctcg cgctactgac ttgtcattgt tggttttgtg caattctggt
     5401 gtagacgtta aacgcccaat catgataagt tagagttagt aacagtattt taacttgctt
     5461 ctctctccat atcatacatc ctcacagaat gtaagaccag ctcacgatat ttccaagcgt
     5521 tgaccaggta ttcaatcact tcaggatctt caatttcaaa accaaagagc agcaacaatc
     5581 taaccgtgta ttcgtttttc aaaattggga cgttgtaagt cacatccacc caatgctcaa
     5641 agcctgaatc tgtctgctct acatttgcta gtttaatatt taaaatcttc atttttattc
     5701 ctcctactta tctattcgta aaagaagata aaaagttatg aaaaaatcat tactttttta
     5761 attcagacag tactttcaga gcaattttgt taatgtcaac aaaattggca accaagcgat
     5821 ttaatactat ttgttgacgc caacaagtca attttcagac aaacaaaaaa accgcaagcc
     5881 tgagcctgcg gtgaaagaac aatttagaaa gtttcctttc tatttattta actgtaatca
     5941 agccatctgg ctctactgtg aagtctggct tatctgccag tgttccgtct ggtttgaggt
     6001 agtaccagcc tgttccgtcc gctgactgga taaaggcgtt tgataccata gcgccttctt
     6061 tagcatctaa gtagtaccaa gtgtccttgt acttgaccca gcctgtcttc atggcacctt
     6121 cttcgttgaa atagtaccac ttctcagcaa ttttcttcca gcctgtagcc atttcgcctg
     6181 agttgtcaaa ccagtaccag ttgccgtctg tgtacttctt ccagcggtct g
//
LOCUS       DAVLGK010000077         6118 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLGK010000077 DAVLGK010000000
VERSION     DAVLGK010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6118
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.078"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            70..312
                     /locus_tag="VXE01_002097"
     CDS             70..312
                     /locus_tag="VXE01_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV0750938.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            314..568
                     /locus_tag="VXE01_002098"
     CDS             314..568
                     /locus_tag="VXE01_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0750939.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            615..1310
                     /locus_tag="VXE01_002099"
     CDS             615..1310
                     /locus_tag="VXE01_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEV0750940.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(1647..2633)
                     /locus_tag="VXE01_002100"
     CDS             complement(1647..2633)
                     /locus_tag="VXE01_002100"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV0750941.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            2827..5295
                     /gene="gyrA"
                     /locus_tag="VXE01_002101"
     CDS             2827..5295
                     /gene="gyrA"
                     /locus_tag="VXE01_002101"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV0750942.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            5295..6038
                     /gene="srtA"
                     /locus_tag="VXE01_002102"
     CDS             5295..6038
                     /gene="srtA"
                     /locus_tag="VXE01_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV0750943.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSNEILTAFNQPYKQFY"
BASE COUNT         1941 a         1009 c         1323 g         1845 t
ORIGIN      
        1 ctttttatat tgactgaaca cctaaaaagt aatacaatgg tgttaccatt aaaaaaggga
       61 gcacaaaaga tgactactat tacattaaaa gtttctgaag ctgataaaac atttatgaaa
      121 gcaatggcta agtttgaagg agtttccctt tcggaactta ttcgcaccaa aactcttgaa
      181 gccctagaag atgaatacga tgctcgtgtg gcagatttag cctatcaaga gtatttagaa
      241 gacttggaaa aaggagttga acccattact tgggaagaaa tgatgcatga tttaggcttg
      301 aaggatgaat aatttgtata aattagttcc aacaagacgt tttatcaagc aattgaaaaa
      361 attggaccgt tatacgcaga agctaattac aaactattta caaaccaatg ttttggaaga
      421 cccaagacga cacggaaagg ctttggttgg taatcgcgtt ggtcaatggc gctatagaat
      481 tggtaattat cgagttatcg tacaaattgt agatgatgaa ttagtcgttg ctactctaga
      541 agttggtcat cggagagata tttattgaat taaagctgag taataacagt atagaaagta
      601 aggagagtaa aaatttgaag aaaaaatggt tttttgcaga ttattatgac acaacaatta
      661 ttttacttgc tttaatctct gttattctgg tattacttgg atttgctgag atgactgatt
      721 tggacaatcc gccttatagt attattgatt tagtaatctg gggtgttttt gtaattgatt
      781 atagttggcg cttttttatt actaaaagaa aatggcgctt tattcttgaa aatatttttg
      841 atttattgac cattctccct ttaaatgcta tttttacagt gtttcgatta ggacgtatct
      901 tccgcttagc aaggctgaca aaattactga aactgactcg tttacttaga ataattggac
      961 ttacaggtaa actagaaaga aaaattagta gattcttacg aacaaatgga ttgatttata
     1021 tcttgtatgt taatatcttt attgttctag tagggagttc gattttatcc gttgttgaag
     1081 aaaaatcctt ctcagatagt ctttggtggg ctcttgtgac agtaactact gttggttatg
     1141 gtgatattgt tccagtttcc ctttttggga aatggctagc agttttactg atgcttgtcg
     1201 gtattggaac aatagggatg ctaacaagtg ctttgacgaa cttttttgta aaggataatc
     1261 cagatgaaca gataaaactt gataaactca aagacgaatt atcgagctaa agaatattaa
     1321 tagagaaaca atctgaaaaa atcgaagaac tacattgaat gataaaagac ttagttgaaa
     1381 aaatatcata aaggtgagac aaaataaaac ttgattcgag gagaaatcaa gtaagtcttg
     1441 acacaataga acgcatatta tcaggtataa aaacttgata ctatgcgttt tatagagaaa
     1501 taaaataaaa tctgaacaaa tcaattagga atttaaagca ttttataaca acgttttaga
     1561 gtgatggggt gctatttcaa cttcaaccta ctataataca gaaaaaaaca actccctgat
     1621 gattcaagga gttgtctata gttaaattag tttttagaag cttcttggaa ttctggattt
     1681 ttccatgctt cgtcaataat agcttgcaat tctttagcag atgcttgcat tttttgagtt
     1741 tctgcatcgt tcaatggaat gtttactgga cgaacgatac catgtgcacc aacaacagct
     1801 ggttgaccga taaagacatt ctcaactccg tattgacctt cttggaatac tgaaagtgga
     1861 agtactgcgt tttcatcgtc aaggattgct ttagtgatac gagcaagggc tactgcgata
     1921 ccgtagtatg ttgcaccttt tttgttgatg attgtgtagg ctgcatcacg aacaccttcg
     1981 aacaattcaa tcaattcagc ttcttgaaca ttttgagtgt ctttaaggaa ttcttcaagg
     2041 tttacaccag cgatgttagc gtgtgaccaa acagcgaact cagagtcacc gtgttcaccc
     2101 atgatgtagg cgtgcactga acgagcatcc acatccaatt tttcagcaag tgcttgacgg
     2161 aaacgagctg agtcaagtga agtacctgaa ccgataacgc gttctttagg gaaaccagag
     2221 aatttccaag ttgagtaagt caaaacgtca actgggttag cagcaacaag gaagatacct
     2281 ttgaaaccag attcaacaac ttgagttacg attgatttgt tgatagcaag gtttttacct
     2341 acaaggtcaa gacgagtttc acctggtttt tgaggtgcac ctgcagtgat cacaacaagg
     2401 tcagcgtctg cacagtcaga gtattgagct gcatagattt ttttaggtga agtgaaggca
     2461 agggcgtgac taaggtcaag cgcatcacca acagcttttt catgcaattg tggaatttcg
     2521 ataattccaa gctcttgtgc aattccttgg ttaacaagtg caaaagcgta agatgaacct
     2581 acagcaccat caccgacaag gataactttt ttgtgttgtt tagttgaagt cattgtttta
     2641 aacatctcct taattttatt aggggatttt ccctagacaa cttcattcta tcacttttaa
     2701 aaaactttgt cacgaatatg ccttatagtt ctcgatgtaa acgttttagt ggtttagagg
     2761 ctgaaataga tgggaattta tggtataatg ttgttactta ctaattgtga aatgaggcat
     2821 ttattaatgc aggataaaaa tttagtgaat gtcaatctga caaaggagat gaaggcaagt
     2881 tttatcgact acgccatgag tgttatcgta gcgcgagctc ttcctgatgt tcgagatggc
     2941 ttaaaacctg ttcaccgtcg cattctctac ggaatgaatg aattgggtgt gaccccagac
     3001 aaaccccata aaaaatctgc tcgtattaca ggggatgtca tgggtaaata tcacccacac
     3061 ggggattcct ctatttatga agccatggtc cgtatggctc aatggtggag ctaccgttac
     3121 atgcttgtag atggtcatgg gaattttggt tccatggatg gagatagtgc tgccgctcaa
     3181 cgttataccg aggcacgtat gagcaagatt gctctggaaa tgcttcgtga tatcaacaaa
     3241 aatacagttg atttcgttga taactatgat gccaatgaac gggaaccctt ggtcttgcca
     3301 gcgcgttttc caaacctttt ggttaatgga gcaactggta tcgcggttgg gatggcaacc
     3361 aatattccac ctcataatct gggtgaaacc attgatgcag tgaagttggt catggataat
     3421 cctgaagtga ctaccaagga cttgatggaa gtcttgcctg gaccagattt tccaactggt
     3481 gctcttgtca tggggaaatc aggtatccat aaggcttatg aaacaggtaa aggttcgatt
     3541 gtcctacgtt ctcgtacaga gattgaaacg actaagactg gtcgtgagcg catcgttgta
     3601 acagaatttc cttacatggt caataaaacc aaggtgcatg agcatattgt tcgcttggtt
     3661 caggaaaaac gcattgaggg tatcacagca gtacgtgatg agtcaaaccg tgaaggtgtt
     3721 cgatttgtta ttgaagtcaa gcgcgacgcc tcagccaatg ttattctcaa taacctcttc
     3781 aaaatgaccc aaatgcaaac caattttggt ttcaatatgc tcgctatcca aaatggtata
     3841 ccgaaaattt tgtctcttcg tcagattttg gatgcttata tcgagcacca aaaagaagtg
     3901 gttgttcgtc gtacacgttt tgataaggaa aaagcggaag cgcgcgctca tatcttagaa
     3961 ggtctcttga ttgcgctaga ccatatcgac gaagtgattc gtatcatccg tgctagtgaa
     4021 acggatgcgg aagctcaagc tgagttgatg agcaagttta agctttctga acgtcaaagt
     4081 caagctatcc ttgatatgcg tcttcgtcgt ttgacaggtt tggaacgcga taagattcaa
     4141 tctgagtatg atgacctctt ggctctgatt gcggatttag cagatattct tgctaagcct
     4201 gaacgtgttt ctcaaattat caaagacgaa ttggatgaag ttaaacgtaa attttctgat
     4261 aaacgccgta cagagttgat ggttggacag atcttgagtc tcgaggatga ggacttgatt
     4321 gaagaatcgg atgtcttgat taccctttct aacagaggct acattaagcg tttggatcag
     4381 gacgagttca ctgctcaaaa acgtgggggt cgtggtgtcc aaggaacggg agtgaaagat
     4441 gatgactttg ttcgtgagtt agtgtcaact agcacccatg atcatctgct cttcttcaca
     4501 aacaagggac gtgtctatcg tcttaaaggt tatgaaattc ctgagtatgg tcggactgcc
     4561 aaagggctac cagtagtcaa tctcttgaaa ttggatgaag acgaaagtat tcagacggtt
     4621 atcaatgttg agtctgatcg cagtgatgat gcttatctct tctttacaac ccgtcacggt
     4681 attgtgaaga gaactagtgt taaggagttt gccaatattc gtcaaaatgg tctcaaagcg
     4741 ctgaatttaa aggatgaaga tgagttaatc aatgtcttgt tggcagaagg agatatggat
     4801 attatcattg gtaccaagtt tggttatgca gttcgcttta atcaatcagc cgttcgtggt
     4861 atgagccgta tcgccactgg tgtgaaaggg gttaaccttc gtgaaggaga cacagttgtt
     4921 ggtgccagct tgattactga tcaagatgag gttcttatta tcacagaaaa aggatatggt
     4981 aagcgtacag tcgctactga atacccaaca aaaggtcgtg gtggtaaggg aatgcagaca
     5041 gctaaaatta ccgaaaaaaa tggcttgctg gccggtctta tgactgttca aggggatgag
     5101 gatttgatga ttatcactga tacaggtgtc atgattcgaa ccaatcttgc caatatttca
     5161 caaacaggac gtgcaactat gggagttaaa gtaatgcgcc tggatcaaga tgctcagata
     5221 gtgactttca caacggttgc ggtggcagaa aaagaagaag ttgggacaga aaacgaaaca
     5281 gaaggtgaag cataatgtct caaaaaaata ataaaaagaa aaacaagcga aaaaatctgc
     5341 tgacaaatat cctagcagga tttctgatat tactgtcact ggctttgatt tttaatactc
     5401 aaattcgaaa tattttcata gtctggaata ccaataagta tcaagttagc caggtatcaa
     5461 aagaaaaatt agaagaaaat caggatacag aaggcaattt tgactttgat tctgtcaaag
     5521 ctatctcttc ggaagctgtt ctaacttctc aatgggatgc tcaaaaatta ccagttattg
     5581 ggggaattgc aattcctgaa ttggaaatga atttgccgat ttttaaagga cttgataatg
     5641 ttaatctctt ctacggagct ggtacaatga aacgcgagca agtaatggga gaaggaaatt
     5701 atagtctagc tagtcaccat atctttggtg ttgataatgc taataaaatg ttattttctc
     5761 ctttagataa tgctaaaaat ggcatgaaga tttatctaac cgataaaaat aaagtttata
     5821 cttatgaaat acgtgaagtc aaacgtgtga caccggatcg tgttgatgaa gttgatgata
     5881 gagatggggt taatgaaatc acattagtaa cctgtgaaga ccttgctgct acagaacgta
     5941 ttattgtcaa aggtgatttg aaagaaacaa aagattattc acaaacatct aatgaaatcc
     6001 taacagcttt caatcaacca tataaacaat tttattaata caaatcagtg aaatcatgga
     6061 tttcactgat tttttaagat tttcataaaa atatagtaaa atgaaataag aataggac
//
LOCUS       DAVLGK010000078         5725 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLGK010000078 DAVLGK010000000
VERSION     DAVLGK010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5725
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.079"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            187..351
                     /locus_tag="VXE01_002103"
     CDS             187..351
                     /locus_tag="VXE01_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0750944.1"
                     /translation="MGIIANVFAGLVGASAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            435..1001
                     /gene="amaP"
                     /locus_tag="VXE01_002104"
     CDS             435..1001
                     /gene="amaP"
                     /locus_tag="VXE01_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV0750945.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            1013..1183
                     /locus_tag="VXE01_002105"
     CDS             1013..1183
                     /locus_tag="VXE01_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV0750946.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1222..1830
                     /locus_tag="VXE01_002106"
     CDS             1222..1830
                     /locus_tag="VXE01_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0750947.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1861..2064
                     /locus_tag="VXE01_002107"
     CDS             1861..2064
                     /locus_tag="VXE01_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0750948.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2174..2446)
                     /locus_tag="VXE01_002108"
                     /pseudo
     CDS             complement(2174..2446)
                     /locus_tag="VXE01_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2591..3037)
                     /locus_tag="VXE01_002109"
     CDS             complement(2591..3037)
                     /locus_tag="VXE01_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0750949.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            3107..3766
                     /locus_tag="VXE01_002110"
     CDS             3107..3766
                     /locus_tag="VXE01_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0750950.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLGLLFLLYSWEWLSLGQVVLITAG
                     VTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(3818..4969)
                     /locus_tag="VXE01_002111"
     CDS             complement(3818..4969)
                     /locus_tag="VXE01_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0750951.1"
                     /translation="MFNGQVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(4984..5701)
                     /locus_tag="VXE01_002112"
                     /pseudo
     CDS             complement(4984..5701)
                     /locus_tag="VXE01_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1779 a         1038 c          961 g         1947 t
ORIGIN      
        1 taaaattata taataataac aatcgaaata attgactttt ctatattaaa gttatataat
       61 agcaataatc aaagaaattg attttttgat attaaaataa aaaggagggt aggcagtgtt
      121 gtgatcaatt attgctggag gtcttattgg tctcttggca ggtaaaatca ctaaaaaagt
      181 agttctatgg gaatcatcgc aaatgtattc gctggtttag tcggggcatc tgcaggacaa
      241 tctcttttag gtagttgggg tccatcaatc gctggaatgg ctttgctccc atctattgta
      301 ggtgcagcga ttgtgattac tgtagtgtca ttctttacag gtagaaagta aacttttcgc
      361 cagtaaagtt agcaaactat ttttaaatca atgacgggaa aaatagttta aatgttaaat
      421 cgaaaggatt gtatatgtca aaagcaaaga aaatatgttt cattattttc tgtattttaa
      481 tcttgacaat tttccttcct gttttgatag attatcatca agttagtgat ctaggtattc
      541 atctacttag ctggagacag aactccgtag ttgaattcta tcttgctaga tatgtctttt
      601 gggggacagt ggttctatca actttagttt tattatccat tttagttgtg atgttttatc
      661 ctaaacgtta cttggaaatc caacttgaaa ctaaaaacga tacattaaaa ttaaagaatt
      721 cggcaatcga aggttttgtt agaagtttgg tgagtgatca tagattgatc aagaacccaa
      781 ctgttcatgt aaatttacga aaaaataaat gtttcgttca tgtagaaggt aaaattcttc
      841 cttcagacaa catcgctgac agatgccaaa taattcaaaa tgaaataact aatggattga
      901 agcagttttt tggtattgag cgtcaagtaa aacttgaagt tgcagtaaaa aattaccaac
      961 caaaacctca aaacaaaaag actgttagtc gtgtgaagta aggaagtaaa aaatggaatg
     1021 gcttaaacaa tatcgatatc caattatcgc tggtctcata ggcgtatttc tggcttgttt
     1081 gattgtctcc tttggcttct tcaaaacaat atttgtattg attttaggag cactgggagt
     1141 tgcagctgga ttatatatcg aaaaaaacta tatagataaa taaaaaaata aaaattacta
     1201 atttaattaa aggagtttca tatgtcaaac gaaaaaaaca caaacactaa cgtagaaaag
     1261 aaagatgcta ctgttgtagc tcacgaaatc aaaggggaac ttacttacga agataaagtt
     1321 atccaaaaaa tcattggtct ttcactagaa aacgtttcag gtcttttggg aatcgatggt
     1381 ggtttcttct caaatcttaa agaaaaaatc gttaacagcg atgacgtaac aagtggtgtt
     1441 aacgtagaag ttggtaaaac acaagttgca gttgacttaa acgttattgt tgagtaccaa
     1501 aaaaatgttc cagctttata ttcagaaatc agagaaatcg tatcttcaga agttgctaaa
     1561 atgactgact tggaaattgt tgaaatcaac gtaaacgttg tcgacatcaa aactaaagaa
     1621 cagcatgaag cagactcagt aagccttcaa gatcgcgtat ctgacgttgc tgaatcaaca
     1681 ggagaattca cttcagaaca attcgaaaaa gctaaatctg gtcttggatc tggtttctca
     1741 actgttcaag aaaaagttag cgaaggtgta gaagctgtta aaggtgcagc aaatggtgta
     1801 gtatctcacg aaaacactcg tgtaaactaa gataaaataa atataacagg agaaattatc
     1861 atgtcagtag aagaaaaatt aaatcaagct aaaggttcta ttaaagaagg tgttgggaaa
     1921 gccatcggtg atgaaaaaat ggaaaaagaa ggagcagctg aaaaagttgt ttctaaagta
     1981 aaagaagttg ccgaagacgc taaagacgct gtagaaggtg ctgtagaagg tgttaaaaac
     2041 atgttgagtg gcgacgataa ataaggttaa aagttacttt atctttttgg taacattagt
     2101 caaaagagtc tgagtcaaga tgattctcag aaaacaaaaa gctagagatt cccaattgcg
     2161 gaactctagc tttttaattt tgcctctttc tcttattata tttcagcagg ttgttggcca
     2221 tgagtatgaa tcccatgtca attctcactt gacgcttacc tctcagatga catctcttat
     2281 aacccaaaca aacctttatc tgcccaaaga cagatttcat atcaatctta cgtttagcga
     2341 aaatttgtct acccttggaa gataaaagtg cctgatattc tttagttttt aaacactggt
     2401 aacgttcatt catatacagt cccttttgag gggctgattc aggttcataa tcgcagtcaa
     2461 cattgatttc aaggctgttt gctttctatc tccccttttt cataatgtat agtaaaatga
     2521 aataataaca ggacgaatcg atcgggacag tcaaatcgat ttctaacaat gttttagaag
     2581 tagaggtgta ctattctagt ttcaatctac tatattttcg tacaggtgct tcaaccattt
     2641 gaacgatttc aaatccttct ttttggtaaa gattctgagc tctttgattt gcctcgaaga
     2701 catttagaga aatactatct atatcttcat tttcaaaggc caaactaaca aatttcctta
     2761 aagcctggct acctaagcct tgctcctgtt tctgggggtt gataaaaaat ctcccgatat
     2821 gaagattgct gtcttctagc ctgattttct ggattagtcc cacaaactct tgttcatcaa
     2881 agattgaaaa gactccttcc aaggcttgaa gggtcagtag aaaaggaatc cttggtccca
     2941 tccattgttc ttgaaaggat ttgcctaggg agttggacca ctggcataca aattgagcgt
     3001 tttctgtgct caccttttct tcaaaacgaa ttgtcatctt ttcctcacca tcttatctat
     3061 gtttctccat tatactattt ctcccatttt ttacgaatag ataagtatga ttgattttta
     3121 tttttttctc gtcgggagca ttctcgcttc ctttcttggt ttggtcattg accgttttcc
     3181 agagcaatcc attatcagtt cagccagtca ctgcgattcc tgtcagactc gcttgcgtcc
     3241 cttagatttg attccgattc tctcacaggt cttcaatcgc ttttgctgtc gctactgcaa
     3301 ggtccgctat cctgtctggt atgccctctt tgaactaggc ttaggactcc tctttctgct
     3361 ttactcttgg gaatggctct ccttggggca agtcgtccta atcaccgctg gtgtgacctt
     3421 gagcatctat gactttcgcc atcaggaata tcccttactg gtctggatga ctttccacct
     3481 aatcctaata gcttcctctg gctggaatct ggtcatggtc tccttccttg ctcttggaat
     3541 tttggctcat tttatcgata tccgcatggg cgcaggggat ttcctctttt tagcttcttg
     3601 tgctctcgtc tttagcataa cggagttact gatcttgatt cagtttgctt ctgcgacggg
     3661 tatcctagcc tttctcctgc aaaagaaaaa ggaaagactt cctttcgtgc ctttcctctt
     3721 acttgctact tgtttgatta tttttggtaa gctactgctt gtctgataaa atccaatttc
     3781 tgccatatgt ccttcatgaa attatttcac agttaaatta taaattattt cttttgtaca
     3841 aagggatgat gttatcaaat cgatctgttc ttctatcttc ttgatactga tcaaaaaatt
     3901 tcatttcgac tgaaaatatt tcgcttataa actgtaaacg aatactttgt ttagacatta
     3961 tagtcgctag actgactaga tgattactca aaacgacgtc cagaatactc tttactttgc
     4021 ttggtttttt aacaaaaatt tgatcatcca aaggttcaat cattttgtaa cctttttgcg
     4081 caatttgacg ataaaagtaa gaatgttgct ttggagtcaa taatcctaac ttaaaagctc
     4141 gatactctaa agcctgtatc gaaacattca aatctgactt caataaaata taactatcag
     4201 gattgctgac acgcttgcca accctctctt caaatttgac taaaaactct tcttttggca
     4261 ataaaaaaca tgatgcaaaa taatttgctt cttgctccaa acgatcgcca tcttcattca
     4321 tatctttata tttatgtaaa agaatatgtc ctagctcatg agctaagtca aaatttcgac
     4381 gtacagatga tttattcgtt cccaacacaa tataaggtct tcccaatttt gaccatgcgc
     4441 tataagcatc agcttggcca ttaattaatc gttccacgat atagatgcct gaacgttcta
     4501 atttataaag caaatcatga ttatcttttg aaatacctaa tttttccctg gcataaagag
     4561 ccaattcctc aatggattct cccttatgat aagattcact cactacatta cttaagtcat
     4621 gaattgtaat attaggtata attacaaaac tttcaaaata atcaatcaga ctatctacct
     4681 tatgtaaata catagtttga atatctattg ttttccgtgt tgctaggtct gcatttctaa
     4741 aggcaattac agaagaatca aatcgaatgc tctcttcttc ctgttcaaaa taagttaaat
     4801 caacatgaaa ttggttggcc aaatgcattt tggttgataa tttaggtttc gtttcgttgg
     4861 actcaaactg ccaaatggct tgttccgtta aattaattct ctgagctaat tctgctctac
     4921 ttaaaccatt taacagccgt aattctttca atacctgacc attaaacatt tacatactcc
     4981 ttactacttt tgaccttctt gtttttctat tcttggaata atttcaaaat cttctgtttc
     5041 cgataattct gaaaaattag gaatatcttg atatttagct tcttcgaaat ggtacgaact
     5101 tgattgaata tactcagaca aatcttgaat caagtgtaac tgaccagttc gtgcatcagg
     5161 cataacaaca tctacagata taatattgtt ttctgagtcc gcctcataag ttaaaatcat
     5221 aaatttttcg atattcgaat ttttagtagc ttgttcaatt tcttgaatca tttcatcaga
     5281 aactaactcc atctgaattg gaaaggaatg actatcttca tcatttttgt aggaagaatg
     5341 ttgattaaga taaagtgtat tcaaataagt agccactctt atttttttgt accaaaggaa
     5401 attggttcgt aagtcgcttc ttacccttta taattaacaa tactttccca tatttttctg
     5461 tatttgtttc aaattctaaa tatccccaag tctgtcctgc taattgtaat ttatactcaa
     5521 acaaatctgc tgatgcaaat gcagtatcaa tatgattagg tcgcgtccat gcataaccat
     5581 tcgacactat cattgtctct cttttttcta gacgttcatc tacataatct ttttgccctt
     5641 tcatcaaagt atctacaatt ttttgtgcct caagcgaatc aaagagatcc tgattcaaca
     5701 taattcttcc tcctccaaat acttt
//
LOCUS       DAVLGK010000079         5320 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLGK010000079 DAVLGK010000000
VERSION     DAVLGK010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5320
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.080"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            323..1669
                     /gene="gdhA"
                     /locus_tag="VXE01_002113"
     CDS             323..1669
                     /gene="gdhA"
                     /locus_tag="VXE01_002113"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV0750952.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGHLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2180..2350)
                     /locus_tag="VXE01_002114"
     CDS             complement(2180..2350)
                     /locus_tag="VXE01_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750953.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2363..2941)
                     /locus_tag="VXE01_002115"
                     /pseudo
     CDS             complement(2363..2941)
                     /locus_tag="VXE01_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(2958..3763)
                     /locus_tag="VXE01_002116"
                     /pseudo
     CDS             complement(2958..3763)
                     /locus_tag="VXE01_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            4019..5066
                     /locus_tag="VXE01_002117"
     CDS             join(4019..4515,4514..5066)
                     /locus_tag="VXE01_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0750954.1"
                     /translation="MKSTKEEIQTIKTLLKDSRTAKYHKRLQIVLFRLMGKSYKEIIE
                     LLDCNQTTIWRNVKKYEEFGLDSLLQETRGGRNHAYMTVEEEKAFLARHLKATEAGEF
                     VTIDALFQAYKKELGRSYTRDAFYQLLKRHGWRNITPRPEHPKKADAQTIVASKNKIS
                     IQEDKKKRFKTSRPFHKVRLMYQDEAGFGRISKLGSCWSPIGVGPHVHSHYIREFRYC
                     YGAVDAYTGESFFLRAGGCNTEWMNVFLEELSQAYPDDYFLLVMDNAIWHKSSILKIP
                     TNIGFAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRILEDVMNQLQDVIQGLEKEVIK
                     SIVNRRWTRMLFESR"
     gene            complement(5178..>5320)
                     /locus_tag="VXE01_002118"
     CDS             complement(5178..>5320)
                     /locus_tag="VXE01_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002907700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0750955.1"
                     /translation="MNGTALFSIKLKKDMLLLLEPNDAHKTGLLVEEPLNIKKVVFKV
                     KI"
BASE COUNT         1675 a          989 c          910 g         1746 t
ORIGIN      
        1 tttttgattt tagtctggta taaatattgc tttcctccaa aatggtcata attttactag
       61 caaatctaac atatcacgga taaattaaca agtgatttct gaattgctaa acattttctt
      121 tccttatagc ataccatact ttaagatttt gtctttgaga aagatatttc caagaaaaac
      181 gttcgttttt ttatctattt tcaaaaaaac caaaaactga attgaaagaa tttttagaaa
      241 atttctgttt tttctttaca gtgaaaaaaa attctgctat aatgtcttat gtaataaaat
      301 atgacaataa aaggagaacg atatgacatc tgctaaagaa tatatccaaa gcgtgtttga
      361 aactgtgaaa gctcgtaacg ggcacgaggc tgaattcctc caagctgttg aagaattttt
      421 caacacttta gaacctgtat ttgaaaaaca ccctgagtat atcgaagaaa atatcttggc
      481 acgtattact gagcctgagc gcgtggtttc tttccgtgtt ccttgggttg accgtgatgg
      541 aaaaattcaa gtaaaccgtg gttaccgtgt tcaattcaac tcagctgttg gaccatacaa
      601 aggtggactt cgtttccacc caactgtaaa ccaagggatc ttgaaattcc tcggatttga
      661 acaaatcttt aaaaatgtct tgactggact tcctatcggt ggaggtaaag gtggatcaga
      721 cttcgatcct aaaggtaaaa cagatgctga agtgatgcgc ttctgccaaa gcttcatgac
      781 tgaattgcaa aaacacatcg gaccatcact tgacgtacct gctggtgata tcggtgttgg
      841 tggacgtgaa attggttacc tttacggtca atacaaacgt cttaaccaat ttgatgctgg
      901 tgtcttgact ggtaaacctc ttggatttgg tggtagcttg attcgtccag aagcaactgg
      961 ttacggtttg gtttactata ctgaagaaat gctcaaagct aacggtaaca gctttgctgg
     1021 taagaaagtc gttatttcag gttctggtaa cgttgctcaa tatgctcttc aaaaagcaac
     1081 tgaactcggt gcaactgtta tttctgtttc tgactcaaat ggttatgtca tcgatgaaaa
     1141 tggtatcgac ttcgatcttt tggttgatgt taaagaaaaa cgtcgtgctc gtttgactga
     1201 gtatgcagct gaaaaagcaa ctgcaaccta ccacgaaggt actgtatgga cttacgctgg
     1261 aaactatgac attgctcttc catgtgccac tcaaaacgaa atcaacggtg aagcagctaa
     1321 acgtttggtt gctcaaggcg ttatctgtgt atctgaaggt gccaacatgc cgagcgacct
     1381 tgatgccatc aaagtttaca aagaaaatgg tatcttctac ggacctgcaa aagctgccaa
     1441 cgctggtggt gtagccgttt cagctcttga aatgagccaa aacagtcttc gcctctcatg
     1501 gactcgtgaa gaagttgatg gccatctcaa agacatcatg acaaacatct tcaacacagc
     1561 taaaacgact tcagaaacat acggtcttga taaagactac cttgcaggag ctaacattgc
     1621 tgcctttgaa aatgtagcaa atgccatgat tgcacaaggt attgtttaag atttatttac
     1681 tcaatcctca atcactacga ttggggattt ttagcttgaa ttaaaaaatt ggaaaatcta
     1741 attaaataaa atgaaatgaa atgaaataaa aactgaacaa attgattgcg gaattcaaac
     1801 caatttctaa catacttcta gaaattaatt tgacttttct aatcgatttg ttcatatctt
     1861 atttcaattt actatactta cttaaccctt tttatactca atgaaaatca aagagcaaac
     1921 taggaagcga gccgcaggct gtacttgagt acggcaaggc aaagctgacg tggtttgaag
     1981 agattttcaa agagtattaa acaaaaagaa aaaccgctac tcctaagaat agcgatttaa
     2041 tcatgttttt aagctactac tgtagttgct ctattattta agtgttatga ataacttcaa
     2101 tatctttaaa gctttttgtt agatttataa tttcaactat agccatctct actccttagt
     2161 ttacagcaaa aaattatgct taattcttat tgtttttgta aacaatcagc gaacccaata
     2221 ctattccatt caacaagcct aaagaaatac catattcaac tggaaaatct aaaaaaattg
     2281 caaacactat tccaatcatc acccctagtg aggctgttgt taaaattaca tattcatttt
     2341 ctttcttcat tttctttaca cctcatttcc tttttgtata taagctgtag tactctccac
     2401 caagctccat taagtactta tgatttcctg actcaacaat cttaccacct ttcattacaa
     2461 aaataatatc cgcatcctta atcgttgaca atctatgagc tacaattatt tgagtacagc
     2521 cctgactttt tatatacttt gttattcttt cctcattaat agtgtctaaa gcactagttg
     2581 cttcatctaa aattacaata ctaggattat ttattaatgc acgtgccagt gctatccgtt
     2641 gtctttgacc acctgaaata tttgaaccca tctctgagat gatagtatta aatttcatcg
     2701 gcatagccat gatttcatca tagatttgaa ctgctttaca aacttcctct atcttttgtg
     2761 aagtaacttc gttctttaaa gttatattat caagaatact tcggttcaat aaaaatgaat
     2821 cctgtggaac tactcctaaa ttttgactta atattttttt atctatttga ttaatattta
     2881 taccatcaaa taaaactttt cctgtatcaa tcttatataa tcctgatggt atttttgata
     2941 atagacttcc tgcaaaacta gaatcctagt tcatgattga taataccagc actcaaattc
     3001 attcgtaatc caaagcgttt acgatgattt cgataggttg ttgaaaacat tttaaacgtt
     3061 tttactttgg caaagatgtt ctcaaccttg cttctatcct tagatagtgc atggttatag
     3121 gttttatctt caactgttag cggcttgagt ttgctggatt tacgtggaat ttgtgcttga
     3181 ggatatatct tcatgagccc ttgataatca ctgtcagcca agattttacc agcttgtccg
     3241 atatttctgc gactcatttt gaacaacttc atatcatgac aatagttcac agcgatatcc
     3301 aaagaaataa ttctcccttg acttgtgaca atcgcttgag tcttcatagc gtgaaatttc
     3361 tttttaccag aataattcgc taattctttt tttaggtcga ttgattttta cttccgtcgc
     3421 atcaatcatt accgtgtcct cagaactgag aggagttctt gaaatcgcaa caccaccttt
     3481 gaacaagagt tacttcaacc cattggctcc gacggattaa gttgctttcg tgaataccaa
     3541 gatcagccgc aatttcttca taagttcgat attctcgcac atattgaaga gtggccataa
     3601 gaaggtcttc taggcttaat ttaggttttc gcccaccttt tgcgtgttta agttgataag
     3661 ctgtttttaa tacagctaac atctcttcaa aagtcgtgcg ttgaacacca acaagacgct
     3721 taaatcgtgc atcggttagt tgtttacttg cttcataatt catagaacta ttataccata
     3781 ttttgtttcg caggaagtct attgaaaaat ctccagacta gagaactcac ggatagttcc
     3841 taatctggag atttcttatt tgcacttttc ttgtacaact ttagtccacg gtaaataggc
     3901 ctctaaaacc tctttgttta cgagagtttc ctcgtttgga agacattcta gaagatagga
     3961 tagatatttc tcgctattta tactagacta aaatcaaaaa gcattataca atagtgatat
     4021 gaaatcaact aaagaagaaa tccaaaccat caaaacactt ttaaaagact ctcgtacagc
     4081 taaatatcat aaacgccttc aaatcgttct atttcgtctg atgggcaaat cttataaaga
     4141 gattatagag cttttagact gtaatcaaac aacgatttgg cgaaatgtaa aaaaatatga
     4201 ggagttcgga ctcgactctc tccttcaaga aacacgtggt ggtcgtaacc atgcatatat
     4261 gacagttgag gaagagaaag cctttcttgc ccgccatttg aaggctacag aggcaggaga
     4321 atttgttaca attgatgcct tatttcaggc ttataaaaag gagttaggtc gttcctacac
     4381 acgtgatgcc ttctatcaac tgttgaagcg ccatggttgg cgaaatatta cgccacgtcc
     4441 agaacatcct aagaaagcag acgctcaaac cattgtcgcg tctaaaaata aaatctcaat
     4501 tcaagaagac aagaaagcgc tttaaaacca gtagaccttt tcataaggtt cgcttgatgt
     4561 accaagatga ggctggtttc ggtagaatca gtaaactggg atcttgttgg tctccaatag
     4621 gagtaggtcc acatgtccat agtcactata tacgagaatt tcgctattgt tatggagctg
     4681 ttgatgccta tacaggcgaa tcatttttct taagagctgg tggatgtaat actgagtgga
     4741 tgaacgtctt tttagaagag ctttcacaag cttatccaga tgattatttt ttactcgtta
     4801 tggacaatgc tatatggcat aaatcaagta tcttaaagat tccgactaat attggttttg
     4861 catttattcc tccatacaca ccagagatga accccattga acaagtgtgg aaagagattc
     4921 gtaaacgtgg atttaagaat aaagcctttc gaattttgga agatgtcatg aatcaacttc
     4981 aagatgtcat acaaggactg gagaaggagg tgataaagtc catcgttaat cggagatgga
     5041 ctagaatgct ttttgaaagc agatgagtgt tactattcta ttttaacaag ctttaaatta
     5101 aatatctata attttagaac tttagaatac aatttcttaa atattttaaa attcttaatc
     5161 cccgaaagta ctttcagtta aatttttacc ttaaaaacaa ctttcttaat attaagtggt
     5221 tcttcaacca ataggcctgt tttatgtgca tcgtttggtt ccaacaaaag taacatatct
     5281 ttctttaatt taatactaaa taaagctgtc ccattcattt
//
LOCUS       DAVLGK010000080         5030 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLGK010000080 DAVLGK010000000
VERSION     DAVLGK010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.081"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..602)
                     /locus_tag="VXE01_002119"
     CDS             complement(<1..602)
                     /locus_tag="VXE01_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750956.1"
                     /translation="MVEIKNLSLDYGEERILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIY"
     gene            complement(590..1147)
                     /locus_tag="VXE01_002120"
     CDS             complement(590..1147)
                     /locus_tag="VXE01_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0750957.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFIAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGISFKNPVKYLEYVSMPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            complement(1048..1677)
                     /locus_tag="VXE01_002121"
     CDS             complement(1048..1677)
                     /locus_tag="VXE01_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0750958.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGSYCVGYFTPCLILWCYLN"
     gene            complement(1688..3409)
                     /locus_tag="VXE01_002122"
     CDS             complement(1688..3409)
                     /locus_tag="VXE01_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750959.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            complement(3393..>5030)
                     /locus_tag="VXE01_002123"
     CDS             complement(3393..>5030)
                     /locus_tag="VXE01_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750960.1"
                     /translation="YKFLDKLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHIL
                     GFRLETNLRKRGIDGLEKASFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAI
                     ITPVLVLALGFIVSIRVGIILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVE
                     YVRGMQVVKIFKANVESFKSFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILI
                     IPIVYFMTSLASAKVILLELIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALY
                     EDMQKDKLVHGNVNNFKNYNIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSG
                     KSTVAKLISGFYNVNKGSIKIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVAL
                     ANKDATKDDVMRALKLAGCDLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKD
                     SKIIIMDEASASIDPDNEFELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIIMDSGKI
                     IERGSDKELMSKDTRYKSLQEMFNSANEWRVSNERVL"
BASE COUNT         1604 a          956 c          658 g         1812 t
ORIGIN      
        1 taataaattc tatgctctgc aacaattatg cttatacctt tctcttttaa tatctttagc
       61 atctttgcca aaacacttat gcttttaata tctaaattcg atgaaggctc atccataact
      121 ataatctttg tacctgctat ataagaagct gcaatgcaaa gaatttgttt ttcaccgccg
      181 gatagattaa atatatttct gttcaaaaga ttttttatcg ggaatatctt aagcatatcc
      241 ttcaaacgcc tgtccatctc ttctcttgca agaccgatat tttccaaata aaataataat
      301 tctaatgtcg tattgacatt aaaaaaatag gtcttaggat tttgaaaaac agttgaaaca
      361 agcattgaga tttgataaag ttccaaattt tttatattct taccatcaat aattatttcg
      421 ccctttgtct ttgcgttatc ataccttaca gctagtccat ttattgaatt tattaaagat
      481 gacttaccat ttccactttt tcctgtaaat agcacgcact ctccctcggc tatggatagt
      541 gatatatcat ctaatatacg ctcttcacca taatcaagac ttaaattttt tatttcaacc
      601 atattaagcc tcccacaata agtccagcaa ccgctaaaac ataaacaaaa tcaattagct
      661 gtatctttac gcgaatgtat ctggtcttgg caattggatt ttctattgcc tttgtttctg
      721 ccgcttttgc aatgtcatct gatatattag atgatataat gagtagtggc atagaaacat
      781 attcaagata tttgactggg tttttaaaac ttatccctct tactctcata gccattttga
      841 tgtttttctt ctcctcctta aaagatggga agaatctaaa cataaccgca ataggtatgg
      901 atacattctt tgaaatctta agcttatcca tcgatgaaat tattgcgcct acatccgagg
      961 tctttatcat aaagcttgct gctataaatg gtaaaataaa cattctaata acaataggta
     1021 tactcaaaaa catcttaact atagggttta attcagataa caccataaaa ttaggcaagg
     1081 agtaaagtat cccacacaat atgatccatt tgaaaagtgt tttttcaata gagccttgcc
     1141 tatatatgct ccaagaattc ctcctaagaa agcacctaag gctactaaag ccatatgagg
     1201 ataagttatt aacttttcta acacatcaac ataatctttt cccatcgtca tcaaagacca
     1261 ctccatatat ttttcttttg ctaaaagcat ttgcattaaa gagctacata tccatgtgct
     1321 gaagattgca taagaaagca tattgtattt aaatgaatta taattaccaa tctttctaat
     1381 taattctgct attatcatta ctataagtga taaaaccaca actacgtagg tatgaccagc
     1441 tgcaaacatc acaagtggtg atatcatacc aaatataaat agtgcccatg gcttttgaac
     1501 cttagccata aataacataa caacagttcc tgcaactatg gctaatactg tcgggtatat
     1561 taagaacaat attggaatca agcccatcat accaactcca aacatgaagg caaaataaat
     1621 tacgccaaaa acaccgatgc ttactaaatc ttttactttt aattttttat tatccattgt
     1681 agtcctccta ataaataaat tcttctgcca tttttgtctt ttctattaaa tttttgtaaa
     1741 tttttgattt ttgtaaaagc tcttcatgct taccttcgct ttctactctt ccgttttgaa
     1801 gaactactat cttgtctgca ttttctatgg atttcattct atgtgaaatg attacaacag
     1861 ttttatcttt aactaaatta tttaaagact cttgaatctt tttctcgttg ttaacatcaa
     1921 ggcttgctgt tatctcatct aagatcaata tcggcgcatc ttttaagaag gctctggcta
     1981 ttgataatct ttgtctttct cctcctgata gctcagctcc gttctcacca ataactgtat
     2041 cgaaaccttt atccattttt tctataaaat ctgtgcaatt tgcaagtttt gctgctcttt
     2101 taacctcttc gtcacttgca tcttgctttc cgattctaat attttccata acgctttgat
     2161 taaagagaac cacatcttgg aaaactatag agaccttatc aaaaagagat tctgttgata
     2221 tttcttttat atctttgcca tcgattaaga tttgtccctt gtcataatca taaagtcttg
     2281 atataagttt caagatagtt gttttaccgc agccacttgc acctaccaaa gcagtgacct
     2341 ctccctgctt agctttaaaa cttacaccat ttaaaacttt tgcgtcttta ttgtaggcaa
     2401 actcaacatc ttttagatca atatcaaatt tttttaagct atagtcatcg ccttcttgta
     2461 aatcttgatt ttgaatttct tttaatcttt ctattttggg cgataaataa aatatttcca
     2521 tcaagccctc tttagatgca tctaaagagt cttttatctt catagcagct agtaaatatc
     2581 ctataaggta gagagaattt atctctttat taataattag atttacgccg acaaatatca
     2641 caacagcaag agatataaag ctaaatattg aagatataga caaagttaaa attgtagtta
     2701 cttccgcctt taagtgtact ctctcactat cttccatttt tttatataag tcatctttaa
     2761 tatccttcga taaattatat gctttaatct ccatttgcat ttcgatattt tcttgaaagc
     2821 tttctgagtt ttttcttaag acatcataat atctattctg tccattaacc tgatattttt
     2881 tagataaagg tataaatata aagcttaaaa tagatgggat aattacagct aaacccatct
     2941 tgacattgcc cgctagcatc attacagata ttaatgggaa aaacagtacc atgccgccca
     3001 cctttggtat tgagtggctc attgcatgct ctatgccttc aatatcagcc atgattgttt
     3061 gtgaaatgtc ggaaatgtca tgtttagaaa agtaagatag aggtaatttt gataaattct
     3121 ccgctgtcct tattcttaaa tctgcacttt cttgataggt tgtgttatat aatttatcgt
     3181 attcgataga aagcaaaata tacattgcta tcaaagtcaa aactgagaat actatataaa
     3241 agccattgct tttgcccata ttttccaaaa cttcctgagc aaaaatcata agtaatatgg
     3301 caggaagcat gtttatacaa taaacgaaaa atgaagccag tgttgcttta cttaaatttc
     3361 ttgctcctcc atctgtaaga gcaaatcttt ttttataaaa ctctttcatt tgaaaccctc
     3421 cattcattcg cactgttaaa catctcttgc aggctcttat accttgtatc ttttgacatt
     3481 aattctttgt cagaccctct ttctataatt tttccactat ccataataat aatttcatca
     3541 aggtctttaa ttgtagatag cctgtgtgca atcatgataa ctgttttatc cttcataaga
     3601 tttttgaaag ctttttgcaa ttcaaactcg ttatctgggt caatagatgc tgatgcttca
     3661 tccataataa taattttgga atcctttaaa attgctctag caattgcaat tctttgtttt
     3721 tctccaccgg ataaataaac accttttgag cctatgattg tattttctct ttctgggaat
     3781 ttgtctaata ttaaatcgca tcctgctaat tttaaggctc tcataacgtc atctttcgtc
     3841 gcatctttat tagctaaagc tacattatca taaatgctct tcttgaataa ttttgaatct
     3901 tgaaaaacaa aggaaatggc tttaattaag gcttcgtcag aatattcact tattgctatc
     3961 ccgcctatct ttatgcttcc tttattaaca ttgtaaaaac ctgatataag ttttgctact
     4021 gttgatttgc ctgatccaga tgaaccgaca agtgcgtagg actttccttc ttctaaatta
     4081 aaggataaat tttcaatgac agctttatca ttataagcaa agctaacatt ctcaaattct
     4141 atattatagt ttttaaaatt attgacatta ccatgcacta atttgtcttt ttgcatatct
     4201 tcgtaaagcg cctctaaagt atctactgca taatttcctt gagaaatata catggagtac
     4261 cacatcattc tcatgaatga aacaaagaga actcctgata aaaataaaat catgataagc
     4321 tcaagtaaaa tcacctttgc gctagctaag ctagtcataa aataaactat aggaataatt
     4381 aaaattgcaa tcagtccaaa aaataaccat tgatacaaaa cataaggcct tttacaagat
     4441 agggaataat cataagcata ctttgagtaa tcttttatag ccttgtaaaa gcttttaaat
     4501 gactctacat ttgctttaaa tatttttaca acttgcattc ctctcacgta ctcaacagtt
     4561 tcagcactta gtttagatag ggattcttgg tatatcttca taaattcttg ctcgcccatc
     4621 atcgccccta aaattaagcc accaattata gtaagagcaa gcaaaattat gccaactctt
     4681 atacttacta taaagccaag tgcaagtaca agtacgggtg tgattattgc ctgagaacta
     4741 tcgggaatca tgtgtgctac cacctgatga gtttgtgcag cattgtcatc tataatcttt
     4801 cttatttgac cagatggatt taagtcaaag aacctaaaac ttgctttttc cagaccatcg
     4861 attccccttt ttcttaaatt tgtttcaagc ctgaatccca agatatgtga aaacattcct
     4921 gagacaaaat aaaatatcgc tccacttgtt agtgtaataa cagattttaa tgctatgctc
     4981 tctgcaccgg ataaatttga attaattatt aacttatcta gaaatttgta
//
LOCUS       DAVLGK010000081         4925 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLGK010000081 DAVLGK010000000
VERSION     DAVLGK010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4925
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.082"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            271..1557
                     /locus_tag="VXE01_002124"
     CDS             271..1557
                     /locus_tag="VXE01_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0750961.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            1572..1883
                     /locus_tag="VXE01_002125"
     CDS             1572..1883
                     /locus_tag="VXE01_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750962.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            2129..2857
                     /locus_tag="VXE01_002126"
                     /pseudo
     CDS             2129..2857
                     /locus_tag="VXE01_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            3192..4070
                     /locus_tag="VXE01_002127"
     CDS             3192..4070
                     /locus_tag="VXE01_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750963.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGLAG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRCLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLD
                     IESSQIVLAVLKKLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFGDIVQEEGLRITMSGNIQSSELFKFFNENSIKVVDF
                     ETKKETLKDIYLNRSK"
     gene            4086..4814
                     /locus_tag="VXE01_002128"
     CDS             4086..4814
                     /locus_tag="VXE01_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0750964.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISASIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
BASE COUNT         1587 a          768 c          974 g         1596 t
ORIGIN      
        1 cattatagga gcaacagagt gggagtagtc atctaaggac taatttatat atttttacga
       61 gtcagtatct tgggatactg gtttttactt ttttagactt tttgactact tgttaaaact
      121 ggggtaattt tcgactgttt aatagttatt atgcaaagtc taaaagatta gaattgtcaa
      181 aacaatccgt ctaggcttga ttttatcctt tatttactat aaaatgagaa ggaaaaatgt
      241 caaactttta tattgcaaat aggagaaatt atgacaaaaa cattaaaacg tcctgaggtt
      301 ttatcacctg cagggacttt agagaagcta aaggtagctg ttcagtatgg agcagatgct
      361 gtctttatcg gtggtcaggc ctatggtctt cgtagccgtg cgggaaactt tactttcgaa
      421 cagatggaag aaggcgtgca gtttgcggcc aagtatggtg ccaaggtcta tgtagcggct
      481 aatatggtta tgcacgaagg aaatgaagct ggtgctggtg agtggttccg taaactgcgt
      541 gatatcggga ttgcagcagt tatcgtatct gacccagcct tgattatgat tgcagcgact
      601 gaagcaccag gccttgaaat ccacctttct acccaagcca gtgccactaa ctatgaaacc
      661 cttgagttct ggaaagagct aggcttgact cgtgtcgttt tagcgcgtga ggtttcaatg
      721 gaagaattag ctgaaatccg caaacgtaca gatgttgaaa ttgaagcctt tgtccatgga
      781 gctatgtgta tttcatactc tggacgttgt actctttcaa accacatgag tatgcgtgat
      841 gccaaccgtg gtggatgttc tcagtcatgc cgttggaaat acgaccttta cgatatgcca
      901 tttgggaaag aacgtaagag tttgcagggt gagattccag aagaattttc aatgtcagcc
      961 gttgacatgt ctatgattga ccacattcca gatatgattg aaaatggtgt ggacagtcta
     1021 aaaatcgaag gacgtatgaa gtctattcac tacgtatcaa cagtaaccaa ctgctacaag
     1081 gcggctgtgg atgcctatct tgaaagttct gaaaagtttg aagctatcaa acaagactta
     1141 gtggacgaga tgtggaaggt tgcccaacgt gaattggcaa caggtttcta ctacggtata
     1201 ccatctgaaa atgagcagtt gtttggtgct cgccgtaaaa tccctgagta caagtttgtc
     1261 gctgaagtgg tttcttatga tgatgcggca caaacagcaa caattcgtca acgaaatgtc
     1321 attaacgaag gggaccaagt tgagttttat ggtccaggtt tccgtcattt tgaaacctat
     1381 attgaagatt tgcatgatgc caaaggcaat aaaatcgacc gcgctccaaa tccaatggaa
     1441 ctattgacta ttaaggtgcc tcaacccgtt caatcaggag acatggttcg tgcattaaaa
     1501 gaaggactca tcaatcttta taaggaagat ggaaccagcg tcacagttcg agcttaagaa
     1561 aggaaaagga aatgatagag gcacagggtt tcttagtgga taagcaaaca agatgcattc
     1621 attaccatag caagctggat attattgctt tacaatgcta tgattgtaaa aagtattatg
     1681 cttgttatcg gtgtcatgat tcattagaaa atcacccttt tgagccgtat cccttatctt
     1741 tgatacagga taagcctatt ttatgtggtg tttgtctaaa actactaaca tataagcaat
     1801 ataaagaaag cttaagttgc cccttttgtt tttctcgctt taatccaggt tgccaaaatc
     1861 ataaggaacg ctattttaaa tagcaaatca tctagttttg aagtaggaga aaactcaatt
     1921 ccaagagaaa atgaagtaaa tcttcccaca ataaaacgca taatatcaag attgttcaat
     1981 acctgatact atgcgttttt aagattttaa agactttttt cctttatctg gtattttgac
     2041 tacttgttaa aaccgggtta attttcaact gtttaacagt tattatgcaa agtctaaaag
     2101 gttagaattg tcaaaacaat ccgtctagag tatgcgtgat gccaaccgtg gtggatgttc
     2161 tcagtcatgc cgttggaagt acgaccttta cgatatgcca tttgggaaag aacgtaagag
     2221 tttgcagggt gagattccag aagaattttc aatgtcagcc gttgatatgt ctatgattga
     2281 ccatatctca gatatgattg aaaatggtgt ggacagtcta aaaatcgaag gacgtatgga
     2341 gtctattcac tatgtatcaa cagtaaccaa ctgctacaag gcggctgtgg atgcctatct
     2401 tgaaagtcct gaaaagtttg aagctatcaa acaagacttg gtggacgaga tgtggaaggt
     2461 tgcccaacgt gaactggcta caggatttta ctatggtaca ccatctgaaa atgagcagtt
     2521 gtttggtgct cgtcgtaaaa tccctgagta caagtttgtc gctgaagtgg tttcttatga
     2581 tgatgcggca caaacagcaa ctattcgtca acgaaacgtc attaacgaag gggaccaagt
     2641 tgagttttat ggtccaggtt tccgtcattt tgaaacctat attgaagatt tgcatgatgc
     2701 taaaggcaat aaaatcgacc gcgctccaaa tccaatggaa ctattgacta ttaaagtccc
     2761 acaacctgtt caatcaggag acatggttcg agctcttaaa gaggggctta tcaatcttta
     2821 taaggaagat ggaaccagcg tcacagttcg tgcttaatgt agttgtttag ttttaaaaaa
     2881 ctatgcaaag ctccatatac aacacttaaa cgagattaaa gaatggcgaa atcccttgat
     2941 gcgcaagaga ttagctgtct tttttatttt ttaagtgata aagtcggagt ttaggcatca
     3001 aagcctatca aattaaacaa agaagcgatg tcttagatat tttgaaaaaa attaataagc
     3061 agaaaactct ctattatttt gttgtagaga gttttttgtt aataaaattt cacaaaatga
     3121 catttatata ttgcattaag ttagatatat gatataatat tgttaaaaag aggcgcaact
     3181 ttttaaaatt aatgagaatc aaagagaaaa ccaataatat taatggagga ataaaaaatg
     3241 taagtaagca ttatggtcat tcaatcattc tcaaagatat aaattttgca cttaacaagg
     3301 gtgaaattgt tggtctagca gggagaaatg gagttggtaa gagtacgttg atgaaaattc
     3361 ttgttcagaa taatcaaccg acttcaggta atattataag cagtgataat gttgggtatt
     3421 taatcgaaga accaaaatta tttttatcta aaacaggttt agagaattta aaatatttgt
     3481 caaatttata tggtgttgac tacaatcaag aaagatttag atgtttgatc caagagttag
     3541 atttgactca gtctattaat aaaaaagtaa agacctattc tttgggtaca aaacaaaaat
     3601 tagctttgct tctaactctc gttacggaac ctgatatatt gattttagat gaaccgacta
     3661 atggtttaga tattgaatca tcacaaatag ttttagcggt tctaaaaaaa ttagctttac
     3721 atgaaaatgt gggaatttta atatcgagtc ataaattaga agacattgaa gaaatttgtg
     3781 agagagttct tttcttggag aacgggcttt tgacatttca aaaagtagga aaagatagtc
     3841 ataatttctt gtttgagata gctttttcat cagctacaga tagagacatt ttcattacca
     3901 aacaagaatt tggggatatt gttcaggaag agggactgag aattactatg tctgggaata
     3961 ttcaaagtag tgagcttttt aaatttttta acgaaaactc tattaaagta gttgattttg
     4021 aaactaaaaa agagacgctt aaagatattt acctaaatcg ttcaaaataa aggaaggtta
     4081 taatcatgaa attaaataaa ttgaattttc ttaaggaaaa tataagaaat ttatattcat
     4141 caggcgtaat atatctcagt ttgcttatct cgtttatacc gccgatattg cttacattct
     4201 ttattctaaa gactcaaggg acatcgcttg gtattaagca tatttcaaac ttttatgcta
     4261 tgctcggtat gttaatggct gttatacatg ctaatcgagt cattagtaga gatttttccc
     4321 acaatacggt aagtttgttt tataatcaac agaagaatcg gatgatttac gtcttgtcta
     4381 attttctata tgccatctca gcttccatta tttatgcttt gaatggcatt gtgttactag
     4441 tcatagtaag taaattgggt attccaggtg atttaggatt agattttata gtagctattg
     4501 tagtcaatac aattttgtta gtcctgtttt attttctatt atcttacatt ttctatttat
     4561 acaaattgaa aagtggcttg gtatttggta ttttagtagc tttactactc tttatcccta
     4621 atatattaaa tacgatgatg atgaatacta gtaatgattt gtttatcaaa gcaattgaac
     4681 ttcttccttt ttattcttta cctgtatttg tggcttcaaa tacgatgtct attagtcagt
     4741 atcttgtgct aatcactaca atcattttat tgtacttttt cactctcaag aaaagcaaga
     4801 agtattcatt ttagtttcat ttagtattat tttgcatacc taaaatacaa taaaaaaatc
     4861 agtcatcttg gtatgctcct gctttcacta ttcaacacgt ttttgactta tactaggctc
     4921 atttc
//
LOCUS       DAVLGK010000082         4863 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLGK010000082 DAVLGK010000000
VERSION     DAVLGK010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.083"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            114..983
                     /gene="rfbA"
                     /locus_tag="VXE01_002129"
     CDS             114..983
                     /gene="rfbA"
                     /locus_tag="VXE01_002129"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV0750965.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSKMLQKAAKKEKGATVFGYHVKDPERFGVVEFDTDMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            984..1577
                     /locus_tag="VXE01_002130"
     CDS             984..1577
                     /locus_tag="VXE01_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV0750966.1"
                     /translation="MTDNFFGKTLAARKIEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     gene            1590..2639
                     /gene="rfbB"
                     /locus_tag="VXE01_002131"
     CDS             1590..2639
                     /gene="rfbB"
                     /locus_tag="VXE01_002131"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV0750967.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            2705..3556
                     /gene="rfbD"
                     /locus_tag="VXE01_002132"
     CDS             2705..3556
                     /gene="rfbD"
                     /locus_tag="VXE01_002132"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV0750968.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAKMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            3619..3953
                     /locus_tag="VXE01_002133"
                     /pseudo
     CDS             3619..3953
                     /locus_tag="VXE01_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272501.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
     gene            4124..4240
                     /locus_tag="VXE01_002134"
     CDS             4124..4240
                     /locus_tag="VXE01_002134"
                     /inference="COORDINATES: protein motif:HMM:NF015247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750969.1"
                     /translation="MPVRLTYDNNYFNDTYQGIPIGGYTQIVEKCWIMKILM"
     gene            4216..4801
                     /locus_tag="VXE01_002135"
                     /pseudo
     CDS             4216..4801
                     /locus_tag="VXE01_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835598.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
BASE COUNT         1554 a          826 c         1093 g         1390 t
ORIGIN      
        1 atatcaactt tgattaatta aaaattagca aaatttattg acattttgtt tttataaatt
       61 gcaataaagg tctaattctg aatttcagtg aatataagaa agggatccta ctaatgaaag
      121 gtattattct tgcaggtggt tcggggacac gattatatcc tttgactcgg gctgcatcaa
      181 aacaacttat gccggtttat gataaaccca tgatttacta tccactttca acattgatgt
      241 tggctgggat tagggatatt ttgataatct caactcctca agatttgcct cgttttaaag
      301 agcttcttca agacggatct gagtttggga ttaaactttc ttatgcagag caaccaagtc
      361 cagatggttt ggcacaagcc tttatcattg gggaagagtt tattggtgat gatagtgttg
      421 ctttgatctt gggggacaat atctatcacg gccctggttt gagcaaaatg cttcaaaaag
      481 cagccaagaa agagaaaggt gcgactgtct ttggctacca tgtcaaggat ccagagcgct
      541 ttggtgtggt tgagtttgat acagacatga atgctatttc catagaagaa aaaccggagt
      601 atcctcgctc caactatgca gttacaggtc tctatttcta tgataatgat gtagtagaga
      661 ttgccaaaag tattaaacca agtcctcgtg gtgaactgga aattacagat gtaaacaagg
      721 cttatctaga acgtggtgat ttgtctgttg agcttatggg acgtggcttt gcttggttgg
      781 atactggcac tcatgaaagt ttactagagg cttcgcagta catcgaaaca gtccaacgga
      841 tgcaaaatgt tcaggtagca aacttagaag aaattgccta tcgtatgggt tatatcagtc
      901 gagaagatgt attggcctta gcccaaccac ttaagaaaaa tgaatacgga cagtatctgc
      961 tccgtttgat tggagaagca tagatgacag ataatttttt cggtaagacg cttgcggcac
     1021 gcaagattga agctattcca ggcatgttgg agtttgatat ccccgttcat ggagataatc
     1081 gtggctggtt taaagaaaat ttccaaaagg aaaaaatgct tccgcttgga tttccagagt
     1141 ctttctttgc agaaggaaaa ttgcaaaaca atgtatcctt ctcacgtaaa aatgtccttc
     1201 gagggctcca cgcagagcct tgggataagt acatctctgt agcagatgga gggaaagttc
     1261 tgggttcttg ggttgatcta cgcgagggtg aaacctttgg gaatacctat cagacagtaa
     1321 ttgatgcaag caagggaatc tttgttcctc gaggcgtagc taatggcttc caagttctat
     1381 cagatacagt gtcatatagc tatctggtca atgattactg ggctctcgag ctcaaaccca
     1441 agtatgcctt tgtgaactac gctgatccaa gccttggtat tgaatgggaa aatattgcag
     1501 aagcagaggt ttcagaagca gataaacatc atcccctact taaggatgta aaacctttga
     1561 aaaaagaaga tttgtaaaaa ggaaagaata tgactgaata caaaaatatt atcgtgacag
     1621 gtggagctgg ctttatcggt tctaactttg tccattatgt ttacgagaac tttccaggtg
     1681 ttcacgtgac agtcctagat aagttgactt atgctggaaa tcgcgcgaat attgaggaaa
     1741 ttttaggtaa tcgtgttgag ttagttgttg gtgacattgc tgatgcggag ttggtagaca
     1801 agttggctgc tcaagcagat gctatcgttc attatgcagc ggaaagccac aatgataatt
     1861 cgctcaatga tccatcgcca tttattcata ctaacttcat tggaacctat actcttttag
     1921 aagctgctcg taagtatgat attcgcttcc accatgtatc gacagatgaa gtttatgggg
     1981 atctcccttt acgcgaagat ttgccaggtc atggagaagg gccgggtgag aaatttacgg
     2041 ctgaaaccaa gtacaatcca agctcgcctt actcatcaac caaggcagcc tcagatttga
     2101 ttgtcaaagc ctgggtgcgt tcttttggag tcaaggcaac gatttccaac tgttcaaata
     2161 actacggtcc ttatcaacat atcgaaaaat tcatcccacg tcagattact aacatcctaa
     2221 gtggtatcaa gccaaaactt tacggtgaag gtaaaaacgt tcgtgactgg attcatacca
     2281 atgaccattc ttcaggagtt tggacaatct tgacaaaagg gcaaatcggt gaaacctact
     2341 tgattggggc tgatggtgag aagaacaata aggaagtttt ggaacttatc cttaaggaaa
     2401 tgggacaagc tgcggatgcc tatgatcatg tgactgaccg tgcaggacat gaccttcgct
     2461 atgcgattga tgctagcaag ctccgtgatg agttggggtg gaaacctgaa tttaccaact
     2521 ttgaagctgg gctcaaggca acaatcaagt ggtatacaga taaccaagaa tggtggaaag
     2581 cagaaaaaga agctgttgaa gccaattatg ctaagactca ggagattatt acagtataaa
     2641 aagcaggaaa tagctgcttt ttattgctat attgggaaga gttatatatt agaaaggtct
     2701 agagatgatt ttaattacag gggcaaatgg ccaattagga acggaacttc gctatttatt
     2761 ggatgaacgt aatgaagaat acgtggcagt agatgtggct aagatggaca ttaccaatga
     2821 agaaatggtt gagaaagttt ttgaagaggt gaaaccgact ttagtctacc attgtgcagc
     2881 ctacaccgct gttgatgcag cagaggatga aggaaaagag ttggacttcg ccatcaatgt
     2941 gacggggaca aaaaatgtcg caaaagcatc tgaaaagcat ggtgcaactc tagtttatat
     3001 ttctacggac tatgtctttg acggtaagaa accagttgga caagagtggg aagttgatga
     3061 ccgaccagat ccacagacag aatatggacg cactaagcgt atgggggaag agttagttga
     3121 gaagcatgtg tctaatttct atattatccg tactgcctgg gtatttggaa attatggcaa
     3181 aaacttcgtt tttaccatgc aaaatcttgc gaaaactcat aagactttaa cagttgtaaa
     3241 tgatcagtac ggtcgtccga cttggactcg taccttggct gagttcatga cctacctagc
     3301 tgaaaatcgt aaggaatttg gttattatca tttgtcaaat gatgcgacag aagatacaac
     3361 atggtatgat tttgcagttg aaattttgaa agatacagat gtcgaagtca agccagtaga
     3421 ttccagtcaa tttccagcca aagctaaacg tccgctaaat tcaacgatga gcctggccaa
     3481 agccaaagct actggatttg ttattccaac ttggcaagat gcattgcaag aattttacaa
     3541 acaagaagtg agataagtag tagaatgatt ttctagtcta ataaaagagg cagataatga
     3601 actccaaagg agcttaagat atacaattat cttgttgttg gtgctggtct ctttggtgca
     3661 gtctttgccc atgaagcagc cttaaaagga aaaaagtaaa agttattgaa aaacgaaatc
     3721 atatcgcggg taatatctat actcgtgaag aggaaggaat tcaagttcat caatatggtg
     3781 ctcatatctt ccatacttct gataaggaga tctgggagta tgtaaatcag tttgcagagt
     3841 ttaaccgtta taccaattct cctgttgcaa actataaggg tgagatttat aaccttcctt
     3901 ttaatatgaa tactttcaat aaactctggg gagttgtaac gccagcagaa gcacaagcta
     3961 agattgagga acaacgtgct attttaaatg gtaaaactcc tgaaaatttg gaagaacagg
     4021 cgatttctct tgtaggtaca gacatctacg aaaaattaat caaagactat acagagaaac
     4081 agtggggcaa atcaactact gaacttccat cctttattat tgtttgccag tacgcctgac
     4141 ctatgataac aattatttta acgataccta tcaagggatt ccaattggtg gatacactca
     4201 aatagttgaa aaatgttgga tcatgaaaat attgatgtag aaacaaacgt tgatttcttt
     4261 gtgaataaag agcaatatct gaaagatttt cctaagattg tctttactgg tatgattgat
     4321 gaattctttg actataagtt gggcgaacta gagtactgta gtcttcgttt tgaaaatgag
     4381 accttggata tggaaaatta ccaaggaaat gcagttgtga actatacgga tgcagaaacc
     4441 ccatatactc gcattattga acacaaacat tttgagtttg ggagtcaagc aaagactatc
     4501 attactaata gaacattcta aaacatggga aaaaggtgat gagccttatt atccagttaa
     4561 taatgatcgt aataatcatt tgtataaatc atataaaaaa cttgctgatg agcaagggaa
     4621 tgttatcttt ggtggccgct taggacacta tcgttattac gatatgcacc aagtaattgg
     4681 agcagctttg cagtgcgtga gaaatgagtt agattcatac tcaatgaaaa tcaaagagca
     4741 aactaggaag ctagccgcag gttgctcaaa gcactgtttt gaggttgcag atggaagctg
     4801 acgcggtttg aagagatttt cgaagagtat aaacaagtaa aactgactac cagttattat
     4861 tta
//
LOCUS       DAVLGK010000083         4652 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLGK010000083 DAVLGK010000000
VERSION     DAVLGK010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.084"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(277..1005)
                     /locus_tag="VXE01_002136"
     CDS             complement(277..1005)
                     /locus_tag="VXE01_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0750970.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1163..2572
                     /locus_tag="VXE01_002137"
     CDS             1163..2572
                     /locus_tag="VXE01_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0750971.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2590..3885
                     /locus_tag="VXE01_002138"
     CDS             2590..3885
                     /locus_tag="VXE01_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0750972.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3890..4198
                     /locus_tag="VXE01_002139"
     CDS             3890..4198
                     /locus_tag="VXE01_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0750973.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNTPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4195..4503
                     /locus_tag="VXE01_002140"
     CDS             4195..4503
                     /locus_tag="VXE01_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0750974.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1572 a          793 c          862 g         1425 t
ORIGIN      
        1 aaaagactca aaaacttctc gtcagtgtaa gaatatttga aacactattt aaaactaaat
       61 aactataaga agtagatcag gtgaacaatt tcagtaccta ctctataagc tatacgaaga
      121 tatttttcaa catgatggat aaaacgatca ctcttttaaa gctatcttat ttagaaaaga
      181 gaaaccattt aagcatagat gggaccttct tgccctgttt taaatttttc ttaaactaga
      241 gtctgtaaaa gattggcttc attttcacat tttctcctag gaggaatgtc gtaatgcaaa
      301 agaattaaat tcaaataaat catagcgatg acgactaatc gagtactcaa acggagttcc
      361 gttatccaaa taagccactt gttctacttc aaataccggt tccgttggaa ggagctgcaa
      421 gtaatgttgc tcattttctg aactagaaga agctcgcaag atttttgtag cactggcaat
      481 atgcaatcct aactttcctt caatgtaatt gtaaatcgat ttttgtaaaa tatcttcagt
      541 aatacctgga ataacatcgg tactcatata agtttgttcc agaacataag gtttaccgtc
      601 aataatacgc aggcggtaaa tattataaac tggactctgc aaagcgacct gtagtttttc
      661 tgctaaaaat tcatttgcaa attctaattt gaagtgaata atcctcgagt caattgtaga
      721 atgagcatct tcagatattt ttgtcagtcc ccggatatct ctttctggaa cgattaattt
      781 tctttttgag ctgccacgag agagaacaaa ggttccctgc ccacgttttc taaaaattaa
      841 gccctcagaa actaacaagt ctaaagcttt tttgatcgtc attcgactac aggcaaactg
      901 tttagctaat gtcatttcat caggcaattg ttcgttcatg gtatatttat tacaaagaat
      961 cttttcacga atctcattgt aaataaataa atattttgta ctcatttaat ctggttctct
     1021 ctataatatt ctaatagtag tataacaaag ttcaagaaat gaggcaaaca caagatatgt
     1081 atcaacaatt tttaaaaatg tctagacaaa ttttaaaatt atgctatact ttatgtatag
     1141 aataatagaa aggaggttga gcatgaaaaa aaagttagta tttcctaatc tgttttggtg
     1201 gggagctgct tctagcggac ctcagacaga aggtcaatat ggaaaagtac atgaaaatgt
     1261 gatggactac tggttcaaaa cgcatccaga agattttttc gataatgtcg gacctcttgt
     1321 agccagtaac ttttttcata cttacaccga agatttccac ttgatgaagg aaattggagt
     1381 taattctttc cgcacttcca tccaatggag tcgactcatc aagaatttag agacaggtga
     1441 gcctgatcca aaaggtattg ctttctacaa tgccatcatt gaagaagcta aaaagaacca
     1501 gatggatctt gtgatgaatt tacatcattt tgatttacca gtggaacttc ttcaaaaata
     1561 cggtggttgg gaaagcaaac atgtagtgga gttattcgtg aagtttgcca agactgcttt
     1621 cacatgcttt ggagataagg ttcattactg gacaactttc aatgagccaa tggtcattcc
     1681 agaagcagga tacttatatg ctttccatta tccaaatcta aaaggaaagg gaaaagaggc
     1741 cgtacaagtc atctataatc taaaccttgc tagtgcaaaa gtgattcaac tatatcgctc
     1801 attaggactt gatggaaaga ttgggattat tttaaacttg acacctgctt atccaagaag
     1861 taattctcca gaagacttag aagcaagtcg atttacagaa gacttcttta acaaagtctt
     1921 cttgaatcca gctgttaaag gaactttccc agaaagattg gtaaaacagc tagagagaga
     1981 tggcgtgtta tggagtcata ccgaaaaaga gcttcaactg atgaaatcaa atacggttga
     2041 ttttcttgga gtaaactact accatccaaa acgtgttcaa gcacaagcaa atcctgagga
     2101 atatcagacg ccctggatgc cagaccaata cttcaaagag tatgaatggc cggagcgtcg
     2161 catgaatcca tatcgtggtt gggaaatttt tccgaaagcc atttatgata ttgctatgat
     2221 tgtgaaggaa gaatatgata atattccatg gtttatcagt gaaaacggaa tgggtgttga
     2281 aaacgaagca cggtttatcg atgaaaatgg agttatcgat gacgtgtatc gtattgaatt
     2341 ttatgaagaa catttaagat ggctacataa agccattgaa gagggaagtc actgttttgg
     2401 ataccacgct tggaccgcat ttgattgctg gtcttggaat aatgcatata agaatcgtta
     2461 cggatttatc tccgttgatt tagaaacgca aaagagaacc atcaagagct caggaagatg
     2521 gtatcgcaaa gtaagtgaca ataacggttt tgaagtagaa attgaggagt aaagagagga
     2581 gatattcaga tgaaaaactc aaaatttata gatcaatttg ccacctttgc tggtaaacta
     2641 gggaaccaaa ttcatttaaa aaccctaaga gatgcattcg taacagtaat gccattatat
     2701 attttggcag gtttaatcgt tcttttgaac aacacggtat ttaagtggat tttccaaggg
     2761 gatacattaa caaaattcca atattgggga ataacaattg caaacggtac tttaagtatt
     2821 tcaggtatga ttattgctgt aatggttggt tatttcttag ctaaaaacag agatttcgaa
     2881 aacccgttag cagcatcaat gctatcatta gtttctttaa ttgtgatgat gccaaataca
     2941 gtttctgtag ttcctgacgg agcaaaagat gcggtaaaca tttcaggtgt tctttcattc
     3001 aacaacacag gtacaggcgc aatgttcgcc ggggttatcg tagcgattat tgcaacagaa
     3061 ttattcattg aattatcaaa cgttaaagct ttacaaatga accttggtga aaatattcca
     3121 ccagctgtta gtagatcatt tagcgtatta cttccagtca tgaccgtcat ctccttattt
     3181 ggggttgttt cagcattatt attcaatata actggaatga acttaatctc aatcattaca
     3241 atctttattc aagaaccaat tcgtcatatt ggtacaagct taatcggggt cattattatt
     3301 tactctttag gaaatatgtt atggctattt ggtattcacc aagcagttat ttacagtgcc
     3361 atcctagaac cattactatt aattaacatt actgaaaaca tcactgcagc aaataatgga
     3421 caagccattc cacacatcat caacttatca caaatacaaa cattcgcttt aatgggtggt
     3481 agtggatcta cattatgttt attaatagca acattcttag tgagtcgcaa tgctgtttct
     3541 aaaaacgtgg ctaaattatc ttttggacct ggtatcttca atatcaatga accagtatta
     3601 ttcggttacc caatcgttta taacatttca ttagctattc catttatcac agttccagtc
     3661 cttggtattt taatcagcta cttagcaaca gttacaggat tcatgagtcc tgcatttata
     3721 caagttcctt ggactacacc agtattctta aatgcatggt tagcaacagc aggggacgtg
     3781 agagcagttc tagttcaatt catcatcttt gcacttggag ttcttctata cattccattt
     3841 atcaaagtta atgacaaagt tgttgaacaa gaaatggaag gttaagatta tgaaacaaat
     3901 tttattagta tgtaatgcgg gaatgtcgac aagtatgctt gttaaaaaaa tgcaacaaag
     3961 tgcgactgaa cgtgggattg aaatttctat ccaagcaaaa tcaatgacag aagctaaaaa
     4021 gaatatccat gaagcagatg tcattctaat tgggccacaa attcgttatg agttacttgc
     4081 tgtgaaagaa attgcaggaa atacccctgt agataccatt gatatgcggg attacggaat
     4141 gatgaatgga gcaaaagttc tggaacaagc acttgcatgg ataggagaaa taagatgaca
     4201 gaagaaatgg aatatatctg ttttcagctc attgccaata gtggagcagc caaatcatcc
     4261 tttattgaag ccatccaact agctaaggcg ggaaatttaa aagaagcgaa aattaaagtt
     4321 gaagaagcgg aagactcctt agtagaagcg cacaagattc actctaatct catacaaaaa
     4381 gaagctactg gagaaaaaat aggattctcc ttgctattta tgcatgcaga agaccaaatg
     4441 gcttcaacag agattattca gttgctatct aaagaattca tcgatctcta tcaaaataaa
     4501 taggaacact gtcattccca tctgtcttta ttaatgacga ctacattgta ggaacctcca
     4561 aaagttggac aaaatgattg aaaggattgg atcctgcatt acacaagatc caatcctttt
     4621 cttttactct agtttttata atatgttgaa tc
//
LOCUS       DAVLGK010000084         4584 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLGK010000084 DAVLGK010000000
VERSION     DAVLGK010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4584
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.085"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..1165
                     /locus_tag="VXE01_002141"
     CDS             <1..1165
                     /locus_tag="VXE01_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750975.1"
                     /translation="AGADGRTPYVHFAYSENADGSGLTMTDNGQRYFGHYSDYEKPDS
                     SDKTKYKWADRWAKVDGGYVNIYALSKNRSIGKSYHVSEFNMDVLSGNITLKAIGSDP
                     YIGAVSSHPGIFIKQQGMKIPVIQGRSICITITNPLFRKNYISFFNSLGKTVKTYKHY
                     NTNKFLISSADLVGVEFIALRYGAGSSNIQIGTVLETKVKVEYGTVHSDWSPAPEDIE
                     SNINSKADQGLTQEQLNALNEKSQILEAEMKAKASMEAFSELEKAYNAFVKLNADSQK
                     KSESDLVEAGRRIDLLTTQFGGLAELKTFIDTYMKSTNEGLIIGKNDASSTIKVSSDR
                     ISMFSAGKEVMYISQGVINIDNGIFTASIQIGRFRTEQYHLNKDVNVIRYIGG"
     gene            1177..3255
                     /locus_tag="VXE01_002142"
     CDS             1177..3255
                     /locus_tag="VXE01_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="structural protein"
                     /protein_id="HEV0750976.1"
                     /translation="MTKFINSSGSLHLNIYIEQVSQDIANNSSRVSWKATVDRDGAYR
                     TYTYGNISNLSVWLNGSSVHSSHPNFDTSGQEFTLASGEVTIPHSGDGTKTFAVWASF
                     DPNNGVHGNITVSANYTLSSIPRSSSVSDNALSGNRRLGSPHTLTIDRKSSLFTHQVW
                     YRVFGSNWIDLGKNHATGVSFVPNIDLARYNTKAKSGTMDICVRTYNGTTQVGNDVYS
                     NGWYFEIPESVKPTFSGITLTDMNTVARQLLSGNNFLQIISDIQVNFNNPSGAYGSTI
                     TGYRAEIVNKNQVTTVNGGRLGMMNFNGSATIRASVVDSRGRQSDTRDITINVIEYFA
                     PAFSFTAFRTRETPNIIQVVRNAKIAPITLSGSQKNVMTLSFKVARLGSTTFTADHGR
                     ASGIWTTQHTLNNSAANMAGNYVATKSFVVIGTLSDKFTSTEFTATVATESVVMSYDK
                     DGRVGIGKVAEQGGAGSLDVLGDIYARNKPIQQYQLTDNNGCGKLIKQDFNTMKETGT
                     WWINGSSQNNPFSGTWGMLEVFRPNPGSHERIQRFTTSTGYMAVRENGFDNNWRPWRY
                     LVQQSKSTNNSDYVALLKSESTPTPWQNAILQNGWNHHRDYGGVQFSKTFDGVVCFKG
                     TCKGGKIARESIILTLPEHFRPSTTLFKTALNNDYGSAVIGIYPNGNVVVKSNVDATW
                     LNFDNVFFKI"
     gene            3315..3578
                     /locus_tag="VXE01_002143"
     CDS             3315..3578
                     /locus_tag="VXE01_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750977.1"
                     /translation="MLKVTKTRQLVTEFFAQDGDQQKLVKTTVINTDNKAVSTISETL
                     HDPELYANNRISMRKHEQELREMRYKIEDAILAELEADAEHKE"
     gene            3588..4004
                     /locus_tag="VXE01_002144"
     CDS             3588..4004
                     /locus_tag="VXE01_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEV0750978.1"
                     /translation="MKIEFFNFLRSVVQTEDGLVLYALTLIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSICLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            4008..4340
                     /locus_tag="VXE01_002145"
     CDS             4008..4340
                     /locus_tag="VXE01_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0750979.1"
                     /translation="MQQITEIITNGAISILVVLAGVVVRAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVASETGFKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            4344..>4584
                     /locus_tag="VXE01_002146"
     CDS             4344..>4584
                     /locus_tag="VXE01_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HEV0750980.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRVLQVGPVNNGSWDVGGGWNA"
BASE COUNT         1513 a          783 c          994 g         1294 t
ORIGIN      
        1 ggctggtgca gatggtagga caccttatgt tcactttgcg tattctgaaa atgcagatgg
       61 atcaggtttg acaatgacag ataacggaca gcgttatttt ggtcattatt cagattatga
      121 gaaacctgat agttcggata aaactaagta caaatgggct gatcgttggg ctaaagttga
      181 tggaggttat gtaaatatct atgcattgtc taagaataga agtattggga aatcttatca
      241 tgtttctgaa tttaatatgg atgtactttc aggaaatatc actctaaaag caattgggtc
      301 agatccatac attggcgccg tttcttctca tccaggtatt tttataaagc aacagggaat
      361 gaaaatccca gttatacaag ggagatctat ttgtataaca ataacaaatc ctttatttag
      421 aaaaaattac atctcgtttt ttaattcatt aggtaaaact gttaaaacat ataagcatta
      481 caacacaaat aaatttttaa tatcttcagc tgatttggta ggtgttgaat ttatcgcttt
      541 acgatatggt gcaggaagct cgaatataca aattggaacc gtactagaga caaaagtaaa
      601 ggtagaatat ggaaccgtgc atagcgactg gtcgcccgct ccagaagata ttgaaagtaa
      661 tattaactct aaagctgatc aggggctgac tcaagagcag ttaaatgccc tcaatgagaa
      721 gtcacagatt ttagaggctg aaatgaaagc gaaagcatcg atggaggcct ttagtgaatt
      781 agaaaaagca tataatgcct ttgtgaaatt aaatgcagat agtcaaaaaa aatctgagtc
      841 tgatttagtt gaagcaggta gaagaattga tttgctgacg acacaatttg gaggattagc
      901 agagcttaaa acattcattg atacttacat gaaaagcaca aatgagggct tgattatagg
      961 taagaatgat gcaagctcta ctattaaggt atcaagtgat agaatatcca tgttttctgc
     1021 aggtaaggaa gttatgtaca tttcgcaagg tgtaataaat attgataatg gtatttttac
     1081 tgcatcaatt caaattggac gttttagaac agaacagtat catcttaaca aagatgtgaa
     1141 tgtcatacga tatataggag gttaaaaaag agggaaatga ctaaatttat caattctagc
     1201 ggttcactac acttgaatat ttacatcgaa caagttagtc aagatatcgc taacaattcc
     1261 tcaagagtta gttggaaagc tactgttgac cgtgatggag cttaccgcac atatacttat
     1321 ggtaatatta gtaacttgtc tgtatggtta aatgggtcaa gtgtgcatag tagtcatcca
     1381 aactttgaca catccgggca agagtttact ttagcaagtg gggaagtaac catcccacac
     1441 agtggtgacg gaactaagac ttttgcagta tgggcatcgt ttgacccaaa caacggagta
     1501 catggaaaca ttaccgtgtc agcaaactat actctttcaa gcattcctcg atctagtagt
     1561 gtaagcgaca atgctctttc aggaaatagg cggctcggaa gtcctcacac tctcactatt
     1621 gatcgcaaat ctagcttatt tactcaccaa gtatggtata gagtgtttgg tagcaactgg
     1681 attgatttag gaaaaaatca cgcaacaggc gtttctttcg tacctaatat tgacctagct
     1741 agatacaaca caaaagcaaa gtctggcacg atggacatat gtgttcgaac atataatgga
     1801 actactcaag ttggaaatga cgtttactca aatgggtggt attttgaaat tccggaaagc
     1861 gtgaaaccta cattttctgg aattacattg actgatatga atactgttgc taggcaacta
     1921 ttgagcggaa ataacttttt acagattatt tccgacattc aggtcaactt taataatcca
     1981 tccggggctt atggttcgac tatcacagga tatcgtgctg aaatcgtaaa caagaatcag
     2041 gttacaactg taaacggtgg taggcttggt atgatgaatt tcaatggttc agcaacgatt
     2101 cgagctagtg tggttgatag ccgaggcagg caatcagata ctagagatat tacaatcaat
     2161 gttattgaat attttgcacc agcttttagt tttacagctt ttaggacgcg ggaaacacct
     2221 aacattattc aagttgtcag gaatgctaaa atcgctccta tcactttatc aggtagtcaa
     2281 aaaaatgtca tgacactatc attcaaagta gctcgactag gtagtacaac ttttacagct
     2341 gatcatggta gagcttctgg tatttggaca actcaacaca ccttaaataa ttcagctgct
     2401 aacatggcag gtaattatgt tgcaaccaaa tcatttgtgg tcataggaac tctatctgat
     2461 aagtttacaa gcacagaatt tacagcaaca gttgcaactg aaagtgtggt aatgagttat
     2521 gacaaagatg gccgtgtggg cattggtaaa gttgcagagc aaggtggtgc agggtcattg
     2581 gatgtcttgg gagatatcta cgctagaaat aaacctattc aacaatatca attgactgac
     2641 aataatggat gtggaaaact tatcaaacag gattttaata cgatgaaaga gactggaacg
     2701 tggtggataa atggtagctc tcaaaacaac cccttttctg gaacttgggg gatgctagag
     2761 gtattcagac ctaatccagg ctctcatgaa cgtattcaac gcttcactac ctcaacagga
     2821 tatatggcag ttagggagaa tggttttgat aacaactgga gaccatggcg ctatctggtg
     2881 caacaatcca agtctactaa taactctgac tatgtagctt tgctaaaatc agaaagcact
     2941 ccgactcctt ggcaaaatgc cattttacaa aatggatgga atcatcacag ggattacgga
     3001 ggtgtccaat tttcaaaaac attcgatggt gttgtttgtt ttaaaggaac atgtaagggc
     3061 ggaaagattg cacgtgagtc aatcatactt actttacctg aacatttcag accatctaca
     3121 acattattca aaactgcttt gaataatgat tacggttcag ccgttatagg aatttatcca
     3181 aatggaaacg tagttgtcaa atctaatgta gatgctactt ggcttaattt tgataatgtg
     3241 tttttcaaaa tataacaacc gtaaaaaatc cctaattatt aacggataat taatttataa
     3301 aggaggaaat gacaatgtta aaagtcacta aaacacgtca gctagtaact gaatttttcg
     3361 cacaagatgg cgaccaacaa aaattggtca aaactactgt aatcaacaca gacaataaag
     3421 ctgtttcaac aatatctgaa acgctgcatg acccggaact gtacgctaac aatcgtatca
     3481 gtatgcgtaa gcatgagcaa gagttacgag aaatgcgcta taagattgaa gatgccattt
     3541 tggcagagct ggaagcagat gctgagcata aggaatagga ggtgtgtatg aaaattgaat
     3601 ttttcaattt tctaagaagt gtcgtacaga ctgaagatgg tttggtcttg tacgctctaa
     3661 cactgattgt ctcaatggaa atcattgatt ttgtgacagg gacgattgcg gcgattatca
     3721 atcctgacat cgagtacaag agcaaaatcg gcattaacgg gctccttcgt aagatttcag
     3781 gggttctctt actgatgatc ctcattccgg cgtccgtttt gttgcctgaa aagacaggtt
     3841 ttgtattctt gcattcaatc tgtctcgggt acatcgcatt tacttttcaa tctctcattg
     3901 aaaattaccg caaattaaaa ggaaatgtta ctctttttca gccgattgta aaagtatttc
     3961 agcgattact tgaaaaagat gatgatacga aaaaaggaga ataacaaatg caacaaatta
     4021 ctgaaatcat tactaatgga gcaatcagca tcctagtcgt tttggcaggg gttgtagtta
     4081 gggcagtcaa ggactacctg gttcaaaaag gtggagaaaa gaccatcaaa atcgttgaaa
     4141 tcttggccaa gaacgcagta aatgccgttg agcaggttgc ctcagagact ggctttaaag
     4201 gcgatgaaaa gctggcacag gctcgtgcta aagtccgtgc tgagcttaca aaatacaata
     4261 ttagcatgac tgacaaagac ttagacacct tcgtagagtc agcagtgaag cagatgaatg
     4321 acgcatggaa aggacgatag ggaatggata tcgatagaaa cagactacgt acaggcttgc
     4381 cacaggttgg ggtgcagcct tatcgacaag tacatgctca ctcaacaggt aaccgcaact
     4441 caaccgtaca gaatgaagcg gattatcact ggcggaaaga cccagaatta ggttttttct
     4501 cgcacgttgt tgggaacggt cgtgtcctgc aggtaggacc tgtgaacaac ggaagttggg
     4561 atgttggggg cggttggaat gctg
//
LOCUS       DAVLGK010000085         4432 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLGK010000085 DAVLGK010000000
VERSION     DAVLGK010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4432
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.086"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            256..1659
                     /locus_tag="VXE01_002147"
     CDS             256..1659
                     /locus_tag="VXE01_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEV0750981.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            1848..2466
                     /locus_tag="VXE01_002148"
                     /pseudo
     CDS             1848..2466
                     /locus_tag="VXE01_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            2481..3221
                     /locus_tag="VXE01_002149"
     CDS             2481..3221
                     /locus_tag="VXE01_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750982.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            3224..>4432
                     /locus_tag="VXE01_002150"
     CDS             3224..>4432
                     /locus_tag="VXE01_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750983.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMN"
BASE COUNT         1545 a          559 c          830 g         1498 t
ORIGIN      
        1 agttatggat ctcgttccaa tatgtgcacg ttggaatgtc agtgcttata tggggggaat
       61 ccaaaggatt ctcccttttt attttaataa gtctgtctag ctatagatat attaagtttg
      121 atagaatttc ttggagattt tgttatggat tataatttca atttggagca tcctttcttt
      181 ttcactaata atgattatag tacagatact agcataaagt actaagtaag tctgcctttt
      241 aattggcacg aagtaatgaa taatgatgag tgggtttatc aataccctat tggaaaattt
      301 gttgaaagac aagggtggaa aatacacatt agttcagagt ataacagttc acatgaattg
      361 ttacaagatg tagcaaaaat ttgccatgaa atgcgaattc catttaaaca tcttagtaca
      421 gaagacaaat ttatcatgcg aaacgggaaa ttggttagtc gaggattttc tggtaaattt
      481 attacatgtt atccaaatca aaatgaatta gagtcggttt tgcaaaggtt agaaagtgcc
      541 ttaaagcaat ataatgggcc atatatttta agcgataaac gttgggatga agcaccaata
      601 tatctgaggt atggtgtgtt taggccgtca agggatgatg aaaagaaggt tgttattgat
      661 gaattaattg ttggcgatga agttgttaaa gatgaacgtt taccagtatt taaaattcca
      721 aaaggtatag tgccccctga ctttttgaat aaatggcttg acaagaaaga taaaaaacag
      781 ggagactttc cctttattat agataatgca attagatttt caaacagtgg tgggatatat
      841 aatgctagac taaaagaaga tgggaaaaaa ataattttaa aagaggctag accgtataca
      901 ggtctaggat ttgatggtac ttattcttca gagagattag cttcggagtg caaagcacta
      961 aaaattctaa atgaatggag tgagatgcct aaaatatact ggtacggtaa gatctgggag
     1021 cacaccttct taggaattga acatatgaag ggcgttccac taaatagatg ggttaccaat
     1081 aattttcctt tatatgaagt tgttgataag accaaagatt atctattgag agtttcaaag
     1141 atagtagaaa aactcatcga tttaacgaat aagtttcatt ctgaaaatgt atatcatcaa
     1201 gatttacatt taggaaatat cttggttaag gatgaagatg agattagtat aatagactgg
     1261 gaacaggctg tcttttcgaa tgatgaaaaa gttgtacata aagttgcagc ccctggtttt
     1321 agagcatggc gagaaacact tcccagtgag atagattggt atggtattag acaaatagct
     1381 cattatttat acatgccact agtaactaca tcggatttga catacaacta tgtaagtcaa
     1441 accaggatag aaggaaaaaa actatttgag tctttgggtt atacaagaga acatatagat
     1501 tatgtagaaa gtttattgtc atatctagat tctaaatgtc cacagattga gaatatttcc
     1561 aggaaaaaag ttttaaaacc catgcatgag attagaacta tcgagagtga gcaagatata
     1621 caagatttta ttataaaagc ttttctttta gtgaactgat aggtattttc ttagcaaacg
     1681 ataaagtttt agggccgata caatcaattg cctattcatt aaataagata aatacaacca
     1741 aagatttaag gaaaccgttt ttaaaatact taagtggaga gaagaatttt atagacgctg
     1801 aacatgataa taacggactg tatacttcat caatagatgt gatacacatg aaagatgttg
     1861 tatattctat tacaccagaa aataaattaa gtattgactt ctcatttaag tcaccattta
     1921 gggtattatt aacaggaact tctggtagtg ggaaaacaac gattttaaat ttaattaatg
     1981 gttctttaaa gccacaaaaa ggttatgtaa atttgttatc acatgggaaa aagagttcag
     2041 attcaatacc aacagttgat cagacaccat atatttttga cactactatt cgtgagaacg
     2101 taactttatt tcaaaatgaa tatttttcag atgatcagat aattgaggtg ttaaaaaagg
     2161 taaatctata tgaagaatta gaaaagatag atatactaaa ttatcaatgt ggtgaaaatg
     2221 gtagtaattt gtctggaggt caaaaacaaa aaatagcttt agctagagct ctgattagaa
     2281 ataataaagt gtacttattt gacgaaatat cagctaattt agataatgat aattcaaatt
     2341 ccatacatga tattctgttc aatttaggta tttcatttat tgaagtttca catcattatg
     2401 acttaaatga caagagatac actgatatat aaattggaaa atggaacact tttcaaaatt
     2461 aagtgattgg aggcaagaat atggataaag attatatatt aaaagtgaaa gggctgtatc
     2521 atcaattttt actgggaaac aataaaacgt tgcaagtgct gaaaaatgtt tctctttctg
     2581 cttcgagagg agaatttata agtattctag gaattagtgg ttctggaaag tcaactttat
     2641 taaaatgtat ttctagtttg cttgaaccaa caagtgggga agtaatttta aatggaatca
     2701 acccctataa aatcagaaat gcaaaattgt caagtataag acgtaacgaa gtatctttta
     2761 tatttcaagc atacaattta ataccttccc tgccggtaat agaaaatata gcacttcctt
     2821 tgcgattatc acaaaaaaaa ttaactatta aaaatgtaga aaacttactc aaaagaatga
     2881 agtttaatgc tggcttaaac gattttgttg gaactctgtc tggtggagaa caacagaagg
     2941 ttgctatagc tagagcggtt attgctgata gtgatataat atttgctgat gagccaactg
     3001 gggctttaga cagcgtttct cgtgaagtaa tttttgaatt attgagagag ttagtagggg
     3061 cgggtaagtg tgtaattatg gtaacgcacg atatagaatt ggcctcgaaa actgatcgtg
     3121 cattaatatt gaaagatgga aaaattttca aagaacttca tagacctagc ggggaagagt
     3181 tgtataaaat cttagaggta caatcaacta cggaggaata gagatgctca gattagttta
     3241 ctatcaattt ttacataata agaaacaatg gttaggcgtt tcaccagtaa tttttgtttc
     3301 gagtttagtt atgggattgg ctgttaatgg ggtaattaat gttgagaata attcgcaagt
     3361 atttgtcgga cttccagatc ctaaaccaat ttttatgttt ccgatagtat tcggaggagt
     3421 aacattattc tttgtgctct ctaacataat aaatatgttg gttgaaattt ttagagatga
     3481 ttacgaactt ctggaggtgt tgggagcaag tctccttcaa ctatcatttc ttgtgggggg
     3541 acagattttt atcatttcct cgattattag ttttattgca tatctatgct ctatatttgt
     3601 tacgtcaaat tattattatt ttttacaata ctttttcggg gaaaatatat tacctgatat
     3661 ccaatttcaa acgagtgctg ttggatgtat cattacagta gtgttgattt catttttagc
     3721 ctttctaagt ggttgctttt atacgttcaa gaagattaga aataggaaga gttctaaaat
     3781 aaggcatgtt ctttcaatag taaaaagaat actgctattg gctggtttta gtgttatctg
     3841 gttgctttct ttgcaacaaa ttttccaaga tagcacaatt ttagcgaagg cccagataat
     3901 attcaatatt gtaatcttag atattgtgat tatttatcaa ttatctcctt ttatacagtc
     3961 atgttttatc aaactacttt ctataattat atttagaaat aattttatgt tcattgtttc
     4021 gaagtggaat ttactatatc gtaagcctta tataaaatct atcagtgctg caattacagg
     4081 agctatatta ctaatttcta gttttcaaat gatttctcag aatatactat ctcaatttca
     4141 agatgacagt gatttagagc taaaagtggc atttattgtc tatgtaggag caccaatttt
     4201 gatagtactt gcaaatatta tttcaattgc atttttgtca tcgcatcaag aaaggattga
     4261 gattcagcaa tttgaaattt taggaacttc taattaccag atggttaaga ttaaagttgg
     4321 tgaggctata tttttgacat ttgttacttc attaattgca tttttactta acattaaaat
     4381 tatggcttta atatactact ctttagagga tattttaata gatgatatga at
//
LOCUS       DAVLGK010000086         4347 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLGK010000086 DAVLGK010000000
VERSION     DAVLGK010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.087"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            2..1027
                     /locus_tag="VXE01_002151"
     CDS             2..1027
                     /locus_tag="VXE01_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0750984.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1017..2024
                     /locus_tag="VXE01_002152"
     CDS             1017..2024
                     /locus_tag="VXE01_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0750985.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2024..3031
                     /locus_tag="VXE01_002153"
     CDS             2024..3031
                     /locus_tag="VXE01_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0750986.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3031..3825
                     /locus_tag="VXE01_002154"
     CDS             3031..3825
                     /locus_tag="VXE01_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750987.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
BASE COUNT         1577 a          638 c          736 g         1396 t
ORIGIN      
        1 tatgaaaaac aaattttttc taatagctat tttagctatg tgtatagttt ttagcgcttg
       61 ttcttctaat tctgttaaaa atgaagaaaa tacttctaaa gagcatgcgc ctgataaaat
      121 agttttagat catgctttcg gtcaaactat attagataaa aaacctgaaa gagttgcaac
      181 tattgcttgg ggaaatcatg atgtagcatt agctttagga atagttcctg ttggattttc
      241 aaaagcaaat tacggtgtaa gtgctgataa aggagtttta ccatggacag aagaaaaaat
      301 caaagaacta aatggtaaag ctaacctatt tgacgatttg gatggactta actttgaagc
      361 aatatcaaat tctaaaccag atgttatctt agcaggttat tctggtataa ctaaagaaga
      421 ttatgacact ctatcaaaaa ttgctcctgt agcagcatac aaatctaaac cttggcaaac
      481 tttatggaga gatatgatta aaattgattc aaaagcctta ggtatggaaa aagaaggtga
      541 tgagttaatc aaaaatactg aagctcgtat atccaaagaa ttagaaaaac atccagaaat
      601 caaaggaaaa atcaaaggaa aaaaagtatt atttactatg attaatgctg cagatacatc
      661 aaaattctgg atttatacta gcaaagatcc aagagcaaat tatttaacag atttaggtct
      721 agttttccct gaatcattaa aagaatttga gagtgaagat agttttgcaa aggaaatttc
      781 tgcagaagaa gcaaataaga taaatgatgc tgatgtaatc ataacttatg gtgatgataa
      841 aactcttgaa gctttacaaa aagatcctct tttaggtaaa ataaatgcaa ttaaaaatgg
      901 tgccgttgct gtaattccag ataatacacc gttagcagcc tcatgcactc caacaccact
      961 ttcaataaac tatactattg aagaatacct aaatctttta ggaaatgcat gcaaaaatgc
     1021 gaaataaaaa acaaataaac ctaggcataa tttttgtaat ctgcctaggt cttcttatta
     1081 caatattttt gtcattaaag cttggaacaa aagaaattaa tatcagagat tttttagcag
     1141 cttttggaat gggcaataca aatgatgatt ttattaaatc aattatatat aaaagaatac
     1201 ctagaactat ttttgcaatt ttagcaggtt ctagtcttgc cataagcggt gtattgatgc
     1261 aatcagttac tagaaaccca atagctgatc caggtatact cggtataaac acaggagcaa
     1321 gtcttagtgt agtaattggt ctttcttttt taggaatttc atcaagcata agccatataa
     1381 gttttgcaat cattggtggc ttagtaagtg caatttttgt atacgcgatt gctgtaagcg
     1441 gaaaagcagg ccttacccct ataaaactag ccttatcagg aacttgtgtt agtatggctt
     1501 taagcagttt tgtaagtttt ttaattttac cgaataataa cgtcttagac aaatttagat
     1561 tttggcaaat aggtagcctt ggagcagcta cattatcttc tatatctaca ctactacctt
     1621 ttataatttt aggtcacttg atagctatat ttatttcatc agatttaaac gctttagcta
     1681 tgggtgatga aatggctgtt ggtcttggag ttaatgttaa taggataaga tcacttgcaa
     1741 taattgcaag tgtgctttta tgttcaagta ttactgcaat tggtggacct attggcttcg
     1801 taggtcttat agttcctcac ttttgtggct tatttataag caaagatata cgcacaatga
     1861 ccatttcttc atcttttata ggtgcagagc tcttgcttat atgtgatata atcggccgta
     1921 tgttaggtaa accaggtgaa attgaagtag ggataattac tgcaataatc gggggtccag
     1981 tacttattta tgtaactatg aaaaatagag gggttaataa ctaatgcaaa atttaattat
     2041 aggtattcaa aaaagaaaaa atagaataac actattctcc tcactatttt tattaataat
     2101 aatcagtcta tcatttttca ttttacttat cggagatgaa agttattctt tttcaacttt
     2161 gattaaagtc ttaaatagtg aaactgttcc tggagctagt ttttcgatta tggaaattag
     2221 attaccaaaa ttattagcag gaattatagc tggctggtct tttggattgg caggatttat
     2281 ctttcaaact atgttaagaa atcctcttgc aagtcctgat ataatcggtg tcacaagttc
     2341 ttcatctatt gcagcggtct tttgcatatt ggtattaaaa acaaatagtt taactactgg
     2401 aattatttca ataacttgtg gactaacatc atctttaata ttatttttac tagctaaaaa
     2461 agatggtttt tcagcagcaa gactgataat attaggtatt ggttttcaag ctgtcacaag
     2521 agcaggcacc tcatttttat tgttgaaagt agcaagatat gaattacaag aagttatgag
     2581 atggctcagt ggctctttat cttttacaaa gttagatgac atacctcttg ttctaatagt
     2641 aagtattatt gctactatat tagttttatt ttttaataaa agactagaaa ttattgaact
     2701 tggtgaagaa atagcaatcg gacttggagc aaatcccgag ctttcaaggc ttgttttaat
     2761 tttttgcgct gtatctttaa ctgctttttc tacttcaatt acaggaccaa tagcttgtat
     2821 atctttttta gctggtccca tagccttaaa tattggcaag aaaagaagcc caatattagc
     2881 tggattggtt ggaattttac tagttttgtt atcagacata ttctctcaaa atattttacc
     2941 agctagatat ccagtaggtg ttgtaactgg cttgttaggt tcaccatact taatatactt
     3001 actaataaaa atgaacagga gaaatatata atgaaaggtc tgtggtcaaa taatcttacc
     3061 tgcggttatg atgaaaaaat aatcttggaa aatataaata taaaaatacc tgaagaaaaa
     3121 atatcagtta ttattgggtc aaatggttgt gggaaatcaa cactcattaa aaccttgtct
     3181 cgacttataa agccattaga gggagaagta ttgcttgata ataaatcaat taattcttat
     3241 aaagaaaaag atttagcaaa acacatagct atattacctc aatctccaat aatccctgaa
     3301 tcaataacag tagctgatct tgtaagccgt ggtcgtttcc cctacagaaa gccttttaag
     3361 agtcttggaa aagatgacct tgaaataata aacagatcaa tggttaaggc caatgttgaa
     3421 gatctagcaa ataacctagt tgaagaactt tctgggggtc aaaggcaaag agtatggata
     3481 gctctagccc tagcccaaga tacaagtatc ctacttttag atgagccaac tacttacttg
     3541 gatatctcat atcaaataga actattagac ctcttgactg atctaaacca aaaatataag
     3601 acaaccattt gcatgatttt gcacgatata aatctaacag caagatacgc tgattaccta
     3661 tttgcaatta aagaaggtaa acttgttgca gagggaaagc ctgaagatat actaaatgat
     3721 aaactagtta aagatatctt taatcttgaa gcaaaaatta tacgtgaccc tatttccaat
     3781 tcgcctctaa tgattcctat tggcaagcac catgttaact cttaataatt gaatattgga
     3841 attcatttaa aagtcgcaac ttttgaactg accctcaaaa gttaggccaa aaaactaact
     3901 aaaggaggtc agttttttaa tggcaactac agcacagaat ttaagataaa attagtaaaa
     3961 gaatatcatg aatgaaaaat aggatataga gaataacagc aatattaaaa agatcaggac
     4021 tgataataaa caaaaagaaa gtacaacgac tagttcaaaa gctaaaactt caagtaaaaa
     4081 gttattcaag aaaatctaga aaatactcat cctacaaagg acgggtagga aaaatataag
     4141 acaacaaaat aaaaagaaat atttattacc gaaaaaaagg ggaaatcgag tcaagtacca
     4201 acaggctcat ctattccaaa aagatattta ctcgatggaa aaactcctag aattagtgct
     4261 acaaatattg acaatggtat cttaggttac tacgaagata tagatgataa aaattataga
     4321 gtttttgaaa attttatatc tgtttca
//
LOCUS       DAVLGK010000087         4276 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLGK010000087 DAVLGK010000000
VERSION     DAVLGK010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4276
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.088"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            84..917
                     /locus_tag="VXE01_002155"
     CDS             84..917
                     /locus_tag="VXE01_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HEV0750988.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQEPLVFGEKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFLGKLKTYPSLNQVLLKSPVKKELLEMLRDSGL
                     NVMYMPIIKTIEELDFVLSFEGINTVAVELVFQDLENPIISKKVIDDLHEKGLLIWVN
                     ALTLSDSIILSAKIDDDTAIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLVEKNKKIK
                     K"
     gene            943..2004
                     /locus_tag="VXE01_002156"
     CDS             943..2004
                     /locus_tag="VXE01_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0750989.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTDFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNELKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            2021..3025
                     /locus_tag="VXE01_002157"
     CDS             2021..3025
                     /locus_tag="VXE01_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0750990.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSETQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIEEKVTMYINPRDIMQF
                     "
     gene            3037..>4276
                     /locus_tag="VXE01_002158"
     CDS             3037..>4276
                     /locus_tag="VXE01_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0750991.1"
                     /translation="MRKSLNWKDWLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEAAKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIVAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFHPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFT"
BASE COUNT         1510 a          592 c          778 g         1396 t
ORIGIN      
        1 aatgaaacgt tccaacttat ctattgacac gttccaagaa atcggataca atgtaattaa
       61 caataaagat aggagaaaat aatttgaatc cattaaaaga atgctatgaa aaaaacggta
      121 tactaattgc agcacaccgt ggtacaaacg gaggaaatat attacaaaac acatcaaaag
      181 cctatttgaa ttccatacgc cataacgcag atatgtttga ggttgatgta attcgttcaa
      241 aagatggaga attttttgca tttcacgatg ggcaagaacc tttagtattt ggtgaaaaaa
      301 ttgatattag aactttgagt tctgaagaga tccaaagaaa ggaatgtttt aattcactga
      361 atgaacccat attacaaaag attgaaaaaa tttctgatgt attaaaaaat tttgagggac
      421 agtctttaat aaatatagat agaagttggt tttactggga taccttccta ggtaagttaa
      481 aaacatatcc atctttgaat caagttcttt taaaatcacc tgtaaaaaaa gaattattgg
      541 aaatgcttag agactctggt ttgaatgtta tgtatatgcc aattatcaaa acaattgaag
      601 agttagattt tgttctttca tttgaaggaa taaatacagt agctgtcgaa cttgtattcc
      661 aagatttaga aaatccaatc ataagtaaga aagtaattga tgatttacat gaaaaaggat
      721 tacttatttg ggttaatgct ttaaccttaa gtgattcaat tattctttcg gctaagattg
      781 atgatgatac agctattgct catgatggcg aatcttgggg gaaattggtt tcaataggat
      841 ttgatattat tcaaacagat tggccattat tactttatca atatctagtt gaaaaaaata
      901 aaaaaataaa aaaataaaaa ataataataa aggagaacta tcatgttcaa aaactttaaa
      961 aagattgcat tcacttcttc actaatttta cttgctgctt gctcaaacaa tgcttcaaat
     1021 acaaatcagt ctactgatga aggaagtgtt gataaatctc aagaaattgt aatctataca
     1081 aattcggctt ctaatggacg tgcagattgg ttacaaacca aagcatcaga gcaaggatac
     1141 aatcttcgtt tggtagatat ttcaggtgga gaactagctg accgtttgat tgcagaaaag
     1201 aataatgctg tggctgatat ggtaattgga ttaaataaat tagaatttaa ccgtattaaa
     1261 gctgaaaaac ttcttgtaaa atactcacca aaatgggctg atgaagtaga tagctctttg
     1321 ggagattctg aagggtatta ttcaccaatt gtaaatcaac cattagtttt gattggtaat
     1381 aaagatgcta aaatgccatc cgactggaca gattttactg attcatctta taaaggtaaa
     1441 tatggtattt caaaattaag tacaggtaca tctaagaaca tctttgcaag tattgtttcg
     1501 agatataaag atgaaaaagg tgagttagga atatctgatg aaggttggaa agttgcaaaa
     1561 gcttacctta aaaatgcaca cgtttatgca gaaggtgaag actatatctc ttcaattatg
     1621 gataataata atgagctaaa atatagtatg atgtggggat ctggtgttct acaaaatcaa
     1681 aaagaacgtg aatataaatt ccaagtaatg tcaccaaaag ttggtgttcc ttatgtaact
     1741 gaacaagttg ggattttaaa tacaagtaag aagcaagcat tattaaaaga atttgtagat
     1801 tggtttggct cttcagaact tcaaaaagaa tggtctgata aatttggttc aattccagct
     1861 aataaaaaag ctctagagca agcaaaagat gaactcaaac agtttgctaa tagtgttaaa
     1921 ccacaagaac ttgactggga gtttatcgga aaaaacatcg attcttggat tgaaaaagca
     1981 cagcttgaat ttgttgaaca gtaatagtta ggattaagtg atgattacat ttaaggatat
     2041 tcaaattaag tataatgatt ttattgccat cgataatctc aatttaacaa tcaatgaagg
     2101 agagtttttc acatttttag gaccaagtgg ttgtgggaaa tcaacaactc ttcgtgcact
     2161 agttggattt ttggagcctt cacaggggca aatactagtt gataatcaag atattacgaa
     2221 tttagatccg gaaaaacgcg aaattggtat tgtgtttcaa agttatgcat tattcccaac
     2281 aatgactgtt tttgataata ttgcttttgg tctaaaagtt aaaaaagttt ctcctgaaat
     2341 tattaaagct aaagttcatg aaattgcgaa aaaaattaat atctcagacg agcaactaaa
     2401 ccgaaatatt tctgaattat cagggggaca acaacagcgt gtagctttag cacgtgcatt
     2461 agtattagaa ccaaaaattc tttgtttgga tgaaccgtta tcaaacctag atgccaaact
     2521 acgagtttcg ttgagaaaag aattgaaacg attgcaaaaa gaactaggaa tcactactct
     2581 ttatgtcaca catgatcaag aagaagcatt aacattatca gataggattg ctgtgtttaa
     2641 taatggattt attgagcaag ttggcacgcc gtatgatatt tataatcaat ccgaaactca
     2701 atttgtctgt gattttattg gctcaatcaa taaaattagc caagaagttc ttaaaaaatt
     2761 acaaggcgag aataaatact ttaaagaaac tgaaggatac atacgcttag agcgtgttaa
     2821 gttagagaaa acttcacctc aagatttatc tataacagga gtaattagtg atattgagtt
     2881 taatggtgta cttattaagt ataaagtaga cttgtcgaat agtgaaagta ttcatattat
     2941 cgaaaagaat gatggactat cacgtcatat aatcgaagaa aaagtcacta tgtacattaa
     3001 tccgcgtgat ataatgcaat tttaaggaga ttgtgcatga gaaagagtct aaactggaaa
     3061 gattggctca taagattagg agttttatgg ctaatctttg ccctgattat ttatccaaat
     3121 attgaacttt tgtctggagt gttttataaa aatggttcat ttactctaga ggcattcaat
     3181 aagattatac actctcagag agcgatgagt agtatattta atagctttat tttggcgatt
     3241 tcaatggtct ttactgtaaa tattgttggg acattgattg ttctactcac agagtactgg
     3301 gatattaggg gttcaaaaat acttaaatta ggttatatga gctctctagt atatggagga
     3361 attgtattag cgacaggata taaatttgtt tatggcgcta atggtcttgt aactaaaacg
     3421 ctctcaagta taattccagg tcttgcccct aactggtttc aaggatttgg tgcagtattg
     3481 tttattatga catttgcttg tacctcaaat cacataatgt ttttaacaaa tgcagttcgt
     3541 agtgttgatt atcatacaat tgaagcagct aaaaatatgg gtgcaagtcc tttaaaagtt
     3601 ttctttagtg tggtttttcc aacttttaaa cctacgttat ttgccttaac catcttaact
     3661 tttttgacag gtctttcagc agtttctgct cctttgatag taggggggaa agattttcaa
     3721 actattaacc cattgattat cagtttcgct aaaactacaa gttcgagaga tttagcagct
     3781 ttactagcta tcatgttagg tttagcaact attctattat tgacactttt gaatcatgtc
     3841 gaaaaaggag gtaattatgt atctgtttcg aaaaccaagg ctagtattaa gaagcagata
     3901 atttcttctc cattatggaa tactcttgct cacattgttg cgtatgtatt gtttgcaatc
     3961 tatatgttac caatagtttt gataattcta tactcgttta cagactcgtt gacgatcaag
     4021 acgggaactt tagatctatc taaatttacg ttagcgaact atgctaattt atttacagat
     4081 gctcaatcat ttcatcctta cctagtcagc gttgtttatg caattttagc tgcggtaatt
     4141 gctacaatta tagcaatagt aatttcacgt attgtacata aaaacaagag taagttcgat
     4201 aaattctttg agtatggtgc actaatacca tggatattgc caggtacatt gattgcacta
     4261 ggattaatgt tcactt
//
LOCUS       DAVLGK010000088         4190 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLGK010000088 DAVLGK010000000
VERSION     DAVLGK010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.089"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            515..1378
                     /locus_tag="VXE01_002159"
     CDS             515..1378
                     /locus_tag="VXE01_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0750992.1"
                     /translation="MIEKMELGEFYKELRLARKLKQTDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDPIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKLLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFK
                     LRLQQYKALID"
     gene            1664..1864
                     /locus_tag="VXE01_002160"
     CDS             1664..1864
                     /locus_tag="VXE01_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV0750993.1"
                     /translation="MLNLQFAETMELTEAELETVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            1931..2596
                     /locus_tag="VXE01_002161"
     CDS             1931..2596
                     /locus_tag="VXE01_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0750994.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            2668..3894
                     /locus_tag="VXE01_002162"
     CDS             2668..3894
                     /locus_tag="VXE01_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0750995.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTIISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         1206 a          754 c          797 g         1433 t
ORIGIN      
        1 gaaaagaatt ttgaactatt tacaaaacaa agtgatctaa ttgttgcaaa tagatggaat
       61 aggggccttg aagcttataa agataaagtt tacacaaggg gaatctggat aagagattaa
      121 ctattgatat taaaaaggca ataatttata aaatttgtac aaaaaaatgt taaattttca
      181 cattttcata gtatactgtt taatagaaag taggttcttt gtaaccgctc cattataaaa
      241 tcctttcact cttccggtat gctattagga aaaacataat tggaggatat tttgagctca
      301 cacctcatcg ttccagtggc tgttccccaa gctcgtgtac tgcccaaaaa agttagacat
      361 tctatttaga acgaggattg agttctgtat tgtacaaggc tcggtccttt tagagtcagc
      421 ttaaggctgg ctttttcaat caccaaagtg tcagaatgtt ttgacaaatg aacacaaata
      481 atgatataat atgcaaaagc taggaggtgg taggatgatt gaaaaaatgg aactggggga
      541 attttacaag gaattacgtt tggcgagaaa gcttaagcag acagatgtgg cttgtgaggg
      601 tctaacagct tctcagttgt ccaagtttga actagggcag tctatgctgt ctgcggataa
      661 gctcatatta gccatccaag ggatcaatgt gacctttgat gagtttgggc acaagctcaa
      721 caactatcaa gaatctccac atatgcagat tggtagaaag gttgtggatc gctttgctca
      781 tcaagatata gctggcttag agcaactgtt ggaggaagtc gagcaagaac agatggcaga
      841 gacttatcgt cgtttgaatg ctattgtaat caaagatgcc atccactcac tagataaaag
      901 ctacccacta gcagaggagg atagcgagtt tttgaccacc tatctctatg ctatcgagtc
      961 ttggacctgg tttgaactct atctcttttg caatactatg cccttcttga gcaatcaaga
     1021 tccgatcttt ttatcaacct ccttactcga aaaatccaaa gaatttaaag agttagtaca
     1081 caatcgattg tatatgaagc aaggactctt aaatatcatc tcagagctca tggagcgcaa
     1141 acttttttct tatatcccaa tctttgaagc cgagctggag agtatgctcc gtccatacga
     1201 tgtttttgag aaattattgt ggcagttttt aaagaagatg agcattttcc ttcaaactaa
     1261 gggaagcaat caaaaagaga ttgaacactt tatccaatct ctgcaagtat tagaaaatcc
     1321 acaattaaca gcccttttta aactacgctt acagcaatac aaagcactta tcgattagtt
     1381 agaaatggga aaaagataat aatctcagca acgattgtca ataatgttaa aacttgtttc
     1441 ttcatatgac ttccctcctc attagtaata actttattat accagggaaa taatcaaata
     1501 taccaaaatc gcaaatctga aatttctata agaaaaaata tcaaatatgc gattttctaa
     1561 aataagccaa ttttcgtgtt atactgtact tgtaaagcac ttgaagcaaa tcctaggtcg
     1621 cagaagtggt ttacaaatga agataattga aggagtgtaa aagatgttaa atttacaatt
     1681 tgcagaaaca atggaattga cagaagctga gttggagaca gtttatggag gggaatttgg
     1741 gaataatgct gttatcccag ccggtgcttg gggagggttc gggacacctt ggtcaatcac
     1801 taatttctgg aagaaaaatt ttaacgatag acctgacttt gattctgacc gccgtcgtta
     1861 ttaatatcca aagcccttgc cttttcttgg gtaggggctg tctttatttc atagtatagg
     1921 aggaaataga atgaaaaaga taatctcaca ccgctacttt attatagttt ttctactagt
     1981 tattgctgac cagaagttca gtgttctagt tttacgcagc gaccttgtta ctgggctatc
     2041 tgactttgcc tattatctgt cggatatgat gttgaatttt cttgtggttt tatttgctct
     2101 tattgctatg atttggtcgg ggaaatggca gaaaatcaat agtagaaagt ttaaaggatc
     2161 ctatcttttc tattccttcc tagctctgct tgcttttgtt gtttggaatt tcgttacctt
     2221 ttttcttttc ccacctactc gaaatgaaat ttcttatcaa catgctgctc cgacttttac
     2281 aggggctaca gcatttttga tgtatttttt ctatcctgtg attgcaggtc ccatttttga
     2341 agagataatc catcggggat tggtgatgac agctctggaa aaaggaaaga aatgggggct
     2401 agatgtactt ggttccgctg ttttatttgg ggtctcgcac attagtaatc acggttgggt
     2461 cttgacagac tttgtcttct atatgggtgg aggtcttata tttgcagtct tatttagaat
     2521 gacaaagtca atttattggc ctattggact gcatatagtc tacaatggca ttggtcagct
     2581 tttgatgtta ctgtaatttt ggttgttagt agtatcgcgg tctatccttg gggaaagatt
     2641 cccatttgaa cttaagaagg agttgtgatg aaagtatttc ttcaaaatag agattttagg
     2701 caattaacta tcaaccagtg gatttcaacg cttggggata cgatttttta tctggccttt
     2761 ttgaattatg tagcagatgc gtcttttgcc cctttggcga ttttacttat cacgatttca
     2821 gaaacccttc cccaagttct acaaatcttt ctgggagttt tggcagattt tcaacatcat
     2881 cgtgtcctaa aatatacaat tattagtttt gcaaaatttt tgctttactc tatagtgtcc
     2941 ctatcgcttt cagggcagtc tttctccttg ttgctagtag catttatttg tctgattaac
     3001 ctcttgtctg acacattgag ttacttttca ggagccatgc tcactccgat tttcattaga
     3061 attattgggc aagaccatct ggcagaagct attggattta aacagtcaac tgttagttta
     3121 gtgaaaacaa tcagtaatat tctaggagga gtcttgctag ggattctctc catccagttc
     3181 atttccttgc tgaacgctct taccttttta atcgcatttt taggtatcct cttcataaaa
     3241 actgacctct tgaaagtaga aaaaacgatt aactatcaag aaggactctc tgtaaaatcc
     3301 ttttgccagc atttgctcca atcatcgaaa ttgatatgga atatgaataa ggtgctcttg
     3361 gttttgttta ttatctctac tagtcaagca gtgataaatg ttacagttcc tgtctctact
     3421 ctatttttga ggaatcaacc ctttttgaat ttacaaacag gtcaatctct tgccttgcta
     3481 tccacttttg aactgtcagc cctgattgtc ggaagccttg taagtggcta tctgcaacat
     3541 accatttcca taaaaacagc tctctatgcc tcacttgtca tccagttgct tcttctagta
     3601 ggatttgcca cagttcgttt tgactggatt ctcatcttta gtaccttgga tgcctttttc
     3661 gcaggtgttc tctctcctag attgcaagaa ctcgtcttta aacaaatacc tgaggagtca
     3721 atgggagcag ttcaatcctc tatcggtgcc attacggttg ttttacctag cttatttaca
     3781 atagctttgg taaccattgc tactagcttt ggaactctgg cagttagctt tgttttattg
     3841 ctatttcttc tagttgcctt tgttatgctt ctgaatattc gtgaaagtat ttagtggaga
     3901 atttctataa tatatgtttg agactggatt gccagtcttt ttatgatggt caaaatcaac
     3961 agactttttt ctcttttctg aatgtgttat aatagactga atctaaaata gtacgaaaca
     4021 attgctaaaa catttataga aattaatttt actttcccaa tcgatttgtt ctcatcttat
     4081 ttcaatctgc tatataatag tccatgctgt ggctggattc ttttcagcct acttatactc
     4141 ttcgaaactc tcttcaaacc acgtcagctt cactttgccg tatatatgtt
//
LOCUS       DAVLGK010000089         3865 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLGK010000089 DAVLGK010000000
VERSION     DAVLGK010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3865
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.090"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..418
                     /locus_tag="VXE01_002163"
     CDS             <1..418
                     /locus_tag="VXE01_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV0750996.1"
                     /translation="KNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEKVTDPSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
     gene            628..3747
                     /gene="phtE"
                     /locus_tag="VXE01_002164"
     CDS             628..3747
                     /gene="phtE"
                     /locus_tag="VXE01_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV0750997.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGISHEKHEEDGYGFDANRII
                     AEDESGFIMSHGNHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTAGYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1449 a          629 c          751 g         1036 t
ORIGIN      
        1 taaaaataag gcagaccaag atagtaaacc tgatgaagat aagggacatg atgaagtaag
       61 tgagccaact caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc
      121 agataatctt tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac
      181 tacagatgag gctgaaattc ctcaagtaga gcattctgtt attaacgcta agatagcaga
      241 tgcggaggcc ttgctagaaa aagtaacaga tcctagtatt agacaaaatg ctatggagac
      301 attgactggt ctaaaaagta gtcttcttct cggaacgaaa gataataaca ctatttcagc
      361 agaagtagat agtctcttgg ctttgttaaa aaaaagtcaa ccggctccta tacagtagta
      421 aaatgaatgg agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa
      481 aaacgtaaca gaaacttgac aaaagtaatt ttaaatagta aactatttac tggttaatta
      541 aatggttaaa taaccggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaac
      601 ttcatcattt attgaaatga gggatttatg aaattcagta aaaaatatat agcagctgga
      661 tcagctgtta tcgtatcctt gagtctatgt gcctatgcac taaaccagca tcgttcgcag
      721 gaaaataagg acaataatcg tgtctcttat gtagatggca gccagtcaag tcagaaaagt
      781 gaaaacttga caccagacca ggttagccag aaagaaggaa ttcaggccga gcaaattgta
      841 atcaaaatta cagatcaggg ctatgtaacg tcacacggtg accactatca ttactataat
      901 gggaaagttc cttatgatgc cctctttagt gaagaactct tgatgaagga tccaaactat
      961 caacttaaag acgctgatat tgtcaatgaa gtcaagggtg gttatatcat caaggtcgat
     1021 ggaaaatatt atgtctacct gaaagatgca gctcatgctg ataatgttcg aactaaagat
     1081 gaaatcaatc gtcaaaaaca agaacatgtc aaagataatg agaaggttaa ctctaatgtt
     1141 gctgtagcaa ggtctcaggg acgatatacg acaaatgatg gttatgtctt taatccagct
     1201 gatattatcg aagatacggg taatgcttat atcgttcctc atggaggtca ctatcactac
     1261 attcccaaaa gcgatttatc tgctagtgaa ttagcagcag ctaaagcaca tctggctgga
     1321 aaaaatatgc aaccgagtca gttaagctat tcttcaacag ctagtgacaa taacacgcaa
     1381 tctgtagcaa aaggatcaac tagcaagcca gcaaataaat ctgaaaatct ccagagtctt
     1441 ttgaaggaac tctatgattc acctagcgcc caacgttaca gtgaatcaga tggcctggtc
     1501 tttgaccctg ctaagattat cagtcgtaca ccaaatggag ttgcgattcc gcatggcgac
     1561 cattaccact ttattcctta cagcaagctt tctgccttag aagaaaagat tgccagaatg
     1621 gtgcctatca gtggaactgg ttctacagtt tctacaaatg caaaacctaa tgaagtagtg
     1681 tctagtctag gcagtctttc aagcaatcct tcttctttaa cgacaagtaa ggagctctct
     1741 tcagcatctg atggttatat ttttaatcca aaagatatcg ttgaagaaac ggctacagct
     1801 tatattgtaa gacatggtga tcatttccat tacattccaa aatcaaatca aattgggcaa
     1861 ccgactcttc caaacaatag tctagcaaca ccttctccat ctcttccaat caatccagga
     1921 atttcacatg agaaacatga agaagatgga tacggatttg atgctaatcg tattatcgct
     1981 gaagatgaat caggatttat catgagtcac ggtaatcata atcattactt cttcaagaag
     2041 gacttgacag aagagcaaat taaagctgcg caaaaacatt tagaggaagt taaaactagt
     2101 cataatggat tagattcttt gtcatctcat gaacaggatt atccaggtaa tgccaaagaa
     2161 atgaaagatt tagataaaaa aatcgaagaa aaaattgctg gcattatgaa acaatatggt
     2221 gtcaaacgtg aaagtattgt cgtgaataaa gaaaaaaatg cgattattta tccgcatgga
     2281 gatcatcatc atgcagatcc gattgatgaa cataaaccgg ttggaattgg tcattctcac
     2341 agtaactatg aactgtttaa acccgaagaa ggagttgcta aaaaagaagg gaataaagtt
     2401 tatactggag aagaattaac gaatgttgtt aatttgttaa aaaatagtac gtttaataat
     2461 caaaacttta ctctagccaa tggtcaaaaa cgcgtttctt ttagttttcc gcctgaattg
     2521 gagaaaaaat taggtatcaa tatgctagta aaattaataa caccagatgg aaaagtattg
     2581 gagaaagtat ctggtaaagt atttggagaa ggagtaggga atattgcaaa ctttgaatta
     2641 gatcagcctt atttaccagg acaaacattt aagtatacta tcgcttcaaa agattatcca
     2701 gaagtaagtt atgatggtac atttacagtt ccaacctctt tagcttacaa aatggccagt
     2761 caaacgattt tctatccttt ccatgcaggg gatacttatt taagagtgaa ccctcaattt
     2821 gcagtgccta aaggaactga tgctttagtc agagtgtttg atgaatttca tggaaatgct
     2881 tatttagaaa ataactataa agttggtgaa atcaaattac cgattccgaa attaaaccaa
     2941 ggaacaacca gaacggccgg aaataaaatt cctgtaacct tcatggcaaa tgcttatttg
     3001 gacaatcaat cgacttatat tgtggaagta cctatcttgg aaaaagaaaa tcaaactgat
     3061 aaaccaagta ttctaccaca atttaaaagg aataaagcac aagaaaactc aaaacttgat
     3121 gaaaaggtag aagaaccaaa gactagtgag aaggtagaaa aagaaaaact ttctgaaact
     3181 gggaatagta ctagtaattc aacgttagaa gaagttccta cagtggatcc tgtacaagaa
     3241 aaagtagcaa aatttgctga aagttatggg atgaagctag aaaatgtctt gtttaatatg
     3301 gacggaacaa ttgaattata tttaccatcg ggagaagtca ttaaaaagaa tatggcagat
     3361 tttacaggag aagcacctca aggaaatggt gaaaataaac catctgaaaa tggaaaagta
     3421 tctactggaa cagttgagaa ccaaccaaca gaaaataaac cagcagattc tttaccagag
     3481 gcaccaaacg aaaaacctgt aaaaccagaa aactcaacgg ataatggaat gttgaatcca
     3541 gaagggaatg tggggagtga ccctatgtta gatccagcat tagaggaagc tccagcagta
     3601 gatcctgtac aagaaaaatt agaaaaattt acagctggtt acggattagg cttagatagt
     3661 gttatattca atatggatgg aacgattgaa ttaagattgc caagtggaga agtgataaaa
     3721 aagaatttat ctgatctcat agcgtaagga atagcagtag aaaaagtctg aatcaaaaat
     3781 gaagttctct caaaagttag aaataaaact ctgactttgg gagaatttca ttttattatt
     3841 aatatataaa atttcttgac ataca
//
LOCUS       DAVLGK010000090         3704 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLGK010000090 DAVLGK010000000
VERSION     DAVLGK010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.091"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            138..365
                     /locus_tag="VXE01_002165"
     CDS             138..365
                     /locus_tag="VXE01_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0750998.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            653..3535
                     /gene="nanA"
                     /locus_tag="VXE01_002166"
     CDS             653..3535
                     /gene="nanA"
                     /locus_tag="VXE01_002166"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV0750999.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLSGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGVIG
                     LEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKGSIESM
                     HNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTK
                     EDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1265 a          617 c          835 g          987 t
ORIGIN      
        1 taaatttact aacacttata aaaagtgata gaatctatct ttatgtatat ttaaagatag
       61 attgctgtaa aaatagtagt agctatgcga aataacagat agagagaagg gattgaagct
      121 tagaaaaggg gaataatatg atatttaagg cattcaagac aaaaaagcag agaaaaagac
      181 aagttgaact acttttgaca gtttttttcg acagttttct gattgattta tttcttcact
      241 tatttgggat tgtccccttt aagctggata agattctgat tgtgagcttg attatatttc
      301 ccattatttc tacaagtatt tatgcttatg aaaagctatt tgaaaaagtg ttcgataagg
      361 attgagcagg aagtatggta taaatagcat aagctgatgt ccatcatttg cttataaaga
      421 gatattttag tttaattgca gtggtgtcct ggtagataaa ctagattggc aggagtctga
      481 ttggagaaag gagaggggaa aattggcacc aatttgagat agtttgttta gttcattttt
      541 gtcatttaaa tgaactgtag taaaagaaag ttaataaaag acaaactaag tgcattttct
      601 ggagtaaatg tcttatttca gaaatcggga tatagatata gagaggatca gtatgaatcg
      661 gagtgttcaa gaacgtaagt gtcgttatag cattaggaaa ctatcggtag gagcggtttc
      721 tatgattgta ggagcagtgg tatttggaac gtctcctgtt ttagctcaag aaggggcaag
      781 tgagcaacct ctggcaaatg aaactcaact ttcggggggg agctcaaccc taactgatac
      841 agaaaagagc cagccttctt cagagactga actttctggc aataagcaag aacaagaaag
      901 gaaagataag caagaagaaa aaattccaag agattactat gcacgagatt tggaaaatgt
      961 cgaaacagtg atagaaaaag aagatgttga aaccaatgct tcaaatggtc agagagttga
     1021 tttatcaagt gaactagata aactaaagaa acttgaaaac gcaacagttc acatggagtt
     1081 taagccagat gccaaggccc cagcattcta taatctcttt tctgtgtcaa gtgctactaa
     1141 aaaagatgag tacttcacta tggcagttta caataatact gctactctag aggggcgtgg
     1201 ttcggatggg aaacagtttt acaataatta caacgatgca cccttaaaag ttaaaccagg
     1261 tcagtggaat tctgtgactt tcacagttga aaaaccgaca gcagaattgc caaatggtcg
     1321 agttcgcctg tatgttaatg gtgttttatc tcgaacaagt ctgaaatctg gcaatttcat
     1381 taaagatatg ccagatgtaa cgcatgtgca aatcggagca accaagcgtg ccaacaatac
     1441 ggtttggggg tcaaatctac agattcggaa tctcactgtg tataatcgtg ctttaacacc
     1501 agaagaggta caaaaacgta gtcaactttt taaacgctca gatttagaaa aaaaactacc
     1561 tgaaggagcg gctttaacag agaaaacgga catattcgaa agcgggcgta acggtaaacc
     1621 aaataaagat ggaatcaaga gttatcgtat tccagcactt ctcaagacag ataaaggaac
     1681 tttgatcgca ggtgcagatg aacgccgtct ccattcgagt gactggggtg atatcggtat
     1741 ggtcatcaga cgtagtgaag ataatggtaa aacttggggt gaccgagtaa ccattaccaa
     1801 cttacgtgac aatccaaaag cttctgaccc atcgatcggt tcaccagtga atatcgatat
     1861 ggtgttggtt caagatcctg aaaccaaacg aatcttttct atctatgaca tgttcccaga
     1921 agggaaggga atctttggaa tgtcttcaca aaaagaagaa gcctacaaaa aaatcgatgg
     1981 aaaaacctat caaatcctct atcgtgaagg agaaaaggga gcttatacca ttcgagaaaa
     2041 tggtactgtc tatacaccag atggtaaggc gacagactat cgcgttgttg tagatcctgt
     2101 taaaccagcc tatagcgaca agggtgatct atacaagggt aaccaattac taggcaatat
     2161 ctacttcaca acaaacaaaa cttctccatt tagaattgcc aaggatagct atctatggat
     2221 gtcctacagt gatgacgacg ggaagacatg gtcagcgcct caagatatta ctccgatggt
     2281 caaagccgat tggatgaaat tcttgggtgt aggtcctgga acaggaattg tacttcggaa
     2341 tggacctcac aagggacgga ttttgatacc ggtttatacg actaataatg tatctcactt
     2401 aagtggctcg caatcttctc gtgtcatcta ttcagatgat catggaaaaa cttggcatgc
     2461 tggagaagcg gtcaacgata accgtcaggt agatggtcaa aagatccact cttctacgat
     2521 gaacaatgaa cgtgcgcaaa atacagaatc aacggtggta caactaaaca atggagatgt
     2581 taaactcttt atgcgtggtt tgactggaga tcttcaggtt gctacaagta aagacggagg
     2641 agtgacttgg gagaaggata tcaaacgtta tccacaggtt aaagatgtct atgttcaaat
     2701 gtctgctatc catacgatgc acgaaggaaa agaatacatc atcctcagta atgcaggtgg
     2761 accgaaacgt gaaaatggga tggtccactt ggcacgtgtc gaagaaaatg gtgagttgac
     2821 ttggctcaaa cacaatccaa ttcaaaaagg agagtttgcc tataattcgc tccaagaatt
     2881 aggaaatggg gagtatggca tcttgtatga acatactgaa aaaggacaaa atgcctatac
     2941 cctatcattt agaaaattta attgggaatt tttgagcaaa aatctgattt ctcctaccga
     3001 agcgaaagtg aagcgaacta gagagatggg caaaggagtt attggcttgg agttcgactc
     3061 agaagtattg gtcaacaagg ctccaaccct tcaattggca aatggtaaaa cagcgacttt
     3121 cctaacccag tatgatagca agaccttgtt gtttgcagta gataaggaag atatcggaca
     3181 ggaaattatt ggtatagcta aaggaagcat cgaaagtatg cataatcttc ctgtaaatct
     3241 agcaggtgcc agagttcctg gcggagtaaa tggtagcaaa gcagcggtgc atgaagttcc
     3301 agaatttaca gggggagtta atggtacaga gccagctgtt catgaaatcg cagagtataa
     3361 gggatctgat tcgcttgtaa ctcttactac aaaagaagat tatacttaca aagctcctct
     3421 tgctcagcag gcacttcctg aaacaggaaa caaggagagt gacctcctag cttcactagg
     3481 actaacagct ttcttccttg gtctgtttac gctagggaaa aagagagaac aataagagaa
     3541 gaattctaaa catttgattt tgtaaaaata gaaggagata gcaggttttc aagcctgcta
     3601 tctttttttg atgacattca ggctgatacg aaatcataag aggtctgaaa ctactttcag
     3661 agtagtctgt tctataaaat atagtagatt gaaataagat gtga
//
LOCUS       DAVLGK010000091         3625 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLGK010000091 DAVLGK010000000
VERSION     DAVLGK010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3625
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.092"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(64..213)
                     /locus_tag="VXE01_002167"
                     /pseudo
     CDS             complement(64..213)
                     /locus_tag="VXE01_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(399..1010)
                     /gene="rpsD"
                     /locus_tag="VXE01_002168"
     CDS             complement(399..1010)
                     /gene="rpsD"
                     /locus_tag="VXE01_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV0751000.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1205..2257)
                     /locus_tag="VXE01_002169"
     CDS             complement(1205..2257)
                     /locus_tag="VXE01_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0751001.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQMETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2254..2952)
                     /locus_tag="VXE01_002170"
     CDS             complement(2254..2952)
                     /locus_tag="VXE01_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0751002.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQI"
     gene            complement(3119..>3625)
                     /locus_tag="VXE01_002171"
     CDS             complement(3119..>3625)
                     /locus_tag="VXE01_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEV0751003.1"
                     /translation="FYQLALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKP
                     DLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT         1007 a          800 c          694 g         1124 t
ORIGIN      
        1 ttaatttata gaaatatttt agcagccaag gtgtactgtt atagattcaa tacactatac
       61 ttagtggttt agctctcctg ttttctcttt tagctttaac cagccataaa tggtattacg
      121 tgagatttgg aaaacgtgtg atgcttctgt tatactacct gttcgctcac aataagagag
      181 aactttttta cgaaaatcta ttgaatatgc cataaaaaga ttataccaca ttgtgtacta
      241 tttttggttc attttactat atcactttgg actatatcgg tctagttatg tctaaacgat
      301 tatagctgga tactaagaga aatcaaaaaa gcactaaggg agaacgtccc aaagtgctta
      361 atatcaaggc ctcaaagcct gtcttattca ataaaatatt acaacatctt gttgtagaat
      421 tcaacgacaa gtgcttcgtt gatttctggg ttgatttcgt cgcgttctgg caagcgagtc
      481 aatgaacctt ccaacttttc agcgtcgaat gatacgaatg ctggacgtcc aagagtagct
      541 tctactgctt caaggattgc tggaactttc aatgattttt cacgaactga gatcacttga
      601 cctggagtta cgcggtatga tgggatatca acgcgtttcc cgtcaacaag gatgtgaccg
      661 tggtttacga attgacgagc ttgacgacga gtagtcgcga gaccaagacg gtaaacaacg
      721 ttatccaaac gacgttccaa aagaagcata aagttgaaac ctaggattcc gcctttgatt
      781 tttgtagctt gtacgaacaa gttacggaat tgtttttcac ctacaccgta agtgaaacga
      841 agtttttgtt tttcagccaa ttgcaaaccg tattctgaca atttagaacg gttgtttggt
      901 ccgtgttgtc ctggtacgta gttacgacgt gccaattctt tacctgtacc tgtaagtgaa
      961 aggccaaggc gacgagcttg tttccaagat ggtcctgtat aacgtgacat atgaatgtcc
     1021 tcctgatata aataatattt cggtggaaat agtcacttag aaagccctga ttcgtgcaga
     1081 tgcccttcgc ctaaacagcc aaggttactt atcataagac acctgttgac gagcttcatg
     1141 ctttcctgct gatatttcac acaaggtcca ttttaccatg aatagctgga tttgtaaagg
     1201 ggttttaggc tttattttca ctaccagaga ggttgagaac gagggtaaag gtacttccta
     1261 gaccgtactg gctgctgact gtgatttccc cacccaattg atgggccaat tcacgcgcaa
     1321 tcgcaagtcc taatccatga ccacctgtct tcatgttacg cgaagtttcg acacgataaa
     1381 ggcgtttgaa aatattttcc aaatcctctg gggcaatgcc ctgcccttca tcggtcacac
     1441 tgattgaaag ctggcccttc tccagcttag ccaccacttc cagcttggtt cctggagcag
     1501 aatatttaaa agcgttatcg accagattca ccaagatacg agaaagctta gcataatctc
     1561 cctcaatccg ggcagactct gggattacct gcaagtggac atctcttctc tcctgctcaa
     1621 tcaaaaactg aaattcactc atgcactcaa ttaagagctt gtccagaaaa atactgtctt
     1681 tactggtagt ttccatctga tttctagctg tgtttagggt caaaaaattc aactcctcaa
     1741 ccaatttatt gagcctctcc gtctggcgtc caatggttgc tagataatga gcttgctccg
     1801 actccttgat aatcccatcc aaaatccctt ctaccgtcgc ttggatcgaa gtgatagggg
     1861 tcttaatatc atgcgacaac tgggcaatca tcaagccctt ttctcgttcg ctttcttcca
     1921 aggaatcaaa gcttacctgc aaatcatggg acatctcatt aaaagtttgc cctaattgct
     1981 gaaattctac aggaccttga acctccaaat ttgaaggaaa atccttggcc gctacccgct
     2041 tggcatgctc cttgagtttg cccaacgacg taaagactgg caataggaga aagagactaa
     2101 tcccagcacc gacaaggctg gcaacgatgg tcatcccaag caaaaagtaa atctcgcctt
     2161 tcgcaatcag cattttttga acagcccaaa aaacaaccaa aatggttaag agggttgaaa
     2221 taatatatcc aaccaaaata taacttttta gtttcatatt tgtcctctcg gtttctctat
     2281 cttatatccc aacccccaaa ctgtcttaat agtgggagtt tggtcactac tatattttgc
     2341 cagctcctgt cgaagagcat ggatatgcac attcaaggta ttggtgtcat ccacgtagtc
     2401 ttctttccag atcttttcat agaggtctgt cttggagaaa actcgctctg gattgctagc
     2461 taaaatccac agcaattcaa atgatttaac agttaaatcc agcatttctt ctcctatttg
     2521 aacttcatga ctactatgat tcatttttag attgccaagg gaaatcagct ctgtttcgcc
     2581 cccacgatga aggcggcgca aaatattgtg gacacgcaaa accagctcac gtgggctaaa
     2641 aggcttagca ataaaatcat ctgctcccaa gctcaggccg taaatcttgt cctgttcact
     2701 ggtcttagca gtaataaata ggaaaggctg ctctggtgat aagtattgaa cctcactgat
     2761 taaatcataa ccatccatcc gaggcatcat gacatctgtg ataatcaaat caatcggttt
     2821 tttcttgaac agctctagcg cttccagtcc atcatgggct accaagacct gataacctgc
     2881 ctgaattaag tatctctgat gaatatctgt gatttctacc tcgtcgtcaa cgagtaaaat
     2941 tgtctttccc atctgtctct cctttgataa aaacagtgct atactgcttt aagtataaca
     3001 ctatttttat tgttttacga tgattttaat ctgctattga aagaaagtcc tgattgctga
     3061 ttgagttgtt aaactaatct tagtcagccc actatccatc atttatttcc ttagctgatt
     3121 agttttcttc ttttttgttt ttcaaaccta gaccaccgag taaacctgca agcgcaagcc
     3181 caaggaaacc aatacttgcc attgatgttt gagtctcacc agtatttggt agcatagctt
     3241 tatcctctga catcatcgta tcagacatct tgttagcaga agcagccatg ttttcacctg
     3301 ccatcgtgtt ggtagaactt gtcatggtgt cagcaggcat gctatctgta gtacctgtag
     3361 catgattgtg attcatcgga gtcacgccag aaccagagtt agaaggtgat aatgaaccat
     3421 ttgctgtgtc tgatgtttct ttaacattta tcttaatagt gactttttta gttgctacga
     3481 tgttgtccaa atctggttta ccgtctttgt taccatagac attgactgta gcgctgtaag
     3541 tttgagtacc atttgctcgg aactggtcaa tgagcgcttg tttttctttg ccagctacat
     3601 ttccgtccaa ggctaattga tagaa
//
LOCUS       DAVLGK010000092         3544 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLGK010000092 DAVLGK010000000
VERSION     DAVLGK010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.093"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..1032)
                     /gene="phtA"
                     /locus_tag="VXE01_002172"
     CDS             complement(<1..1032)
                     /gene="phtA"
                     /locus_tag="VXE01_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV0751004.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNISNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELE"
     gene            complement(1286..3019)
                     /gene="ptsP"
                     /locus_tag="VXE01_002173"
     CDS             complement(1286..3019)
                     /gene="ptsP"
                     /locus_tag="VXE01_002173"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV0751005.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(3025..3288)
                     /locus_tag="VXE01_002174"
     CDS             complement(3025..3288)
                     /locus_tag="VXE01_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV0751006.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
BASE COUNT          940 a          760 c          675 g         1169 t
ORIGIN      
        1 ttccaattca gacatttgtt cataagggat aaagtggtaa tggttaccat gagggacagc
       61 tacacctctg gcggttcgac ttgtgatttg cgctgggtcg aaaacaaggc catcagattc
      121 tacatggcgt tgactcaaag gcagtttgta gagctgtttc aagagactat caatgtcatt
      181 actttgactt gcttgactgt tagtgttgct gttgttgctt atgttagtat ttgtagttcc
      241 tggattgctt acagaaggta cccagtttgt tcttgaagtg ttatcgctat tttgtcggcg
      301 ataggttctt gaatttgaca gatttccccg accagatagg aaggcttctg cagcagctaa
      361 ctcgctagct gataactcat tcttaggaat gtaatggtaa tggtcgccgt gaggaacgat
      421 ataagcatca cccgtgtcct caatgatatc agaagcatta aagatataac catcatctgt
      481 ggtgtagcgt ccctgtgaac gtgcaaaggc taccgcacca tcgtttgctg aagtccctcc
      541 ttcacgatgc tgactatgtt cttgtttttg ccgattgatt tcttcttttg tacggacatt
      601 atccgcgtgg gcagcatcct taaggtaaac atagtatttt ccatctacct tgataacata
      661 tccacccttg acctcattaa caatatcctc atcttttagc ttatagtttg gatctttcat
      721 gagtaattct tcactgaaaa tcgcatcata aggaacctta ccattgtaat aatgatagtg
      781 gtcgccatgt gaagtgacat agccttggtc tgttatcttg atgacgattt gctcagcatt
      841 gattccttca cgcttgctaa cctcatcagg agtcaaattc tccgtttttt gcgtcgcttg
      901 ttttccatct atataggaaa cacgattatt ttccttaacc gttctagctt gatacagtcc
      961 caactcgtaa gaacaaacac ttaaaatcaa agctgccgca gaaccaacaa ggtatttctt
     1021 attaattttc atcgaaactc tctttctatt tgatatttct agttgcaatt catttctaaa
     1081 ttgcagaaac tcctctctat tacttaactg gttaatagtt tactcctaaa tctccaactt
     1141 gtcaagaatt ttatgaacca tttaagtatt ttttgttctg accactactt tttcaaggtt
     1201 ggactttcta taaaaaagat tttcttgaaa attcttttta aaatatcaaa aaaatccctg
     1261 taactgagtt gcagggactt ttcgattaat caaaattaac gtattctttt tgaagttcaa
     1321 gaacttcttc cattgttgag cattctgtaa gggcacggtt tgcgtactct tccatcttag
     1381 ctgtgtcgag tttcttcatc aagctgcgtg tacgaagtac agatgttgct gacatagaga
     1441 actcatccaa gcccattccg acaagaagtg gaacagcttg ttggtcacca gccatctcac
     1501 cacacatacc agcccattta ccttcagcgt gagctgcttt gatcacattg ttaatcaagc
     1561 gtaggattga tgggttgtat ggttggtaaa ggtatgaaac ttgttcgttc atacggtctg
     1621 ctgccattgt atattggatc aagtcgtttg taccaattga gaagaagtca acttctttag
     1681 caaattggtc tgcaagcata gccgctgcag gaatctcgat catgatacca acttggatgt
     1741 tatccgcaac tgcaacacct tcagcaagaa ggtttgcttt ttcttcatca aagactgctt
     1801 tcgctgcacg gaattctttc aagagcgcaa ccattgggaa catgatacgc aattgaccgt
     1861 gaacagacgc acgaagaaga gcacggattt gtgtgcggaa catagcatct ccagtctcag
     1921 agatagagat acgaagagca cggaatccaa ggaatgggtt catttcgtga ggcatatcga
     1981 agtaaggaag ttccttatct ccaccgatat ccattgtacg aacgacaaca ggtttaccgt
     2041 tcattccttc aagaacagcc ttgtatgctt catactgctc atcttcagtt gggaagtctt
     2101 gagaatccat gtacaagaac tctgtacggt aaagtccaac agcttctgca ccgttgttgt
     2161 taacaccttc aacgtctttt ggagtaccaa tattggcagc caactcgaag tgtttaccgt
     2221 cagcagtcac tgtttgagca tctttcaaaa gtgcccattc agctttttgt ttcgcatagg
     2281 cttcaccagc tgctttaaat tctgccgctt gttcatctgt tgggttgata atcacttctc
     2341 cagtgatccc gttaacagca aggatgtcac cgtctttaac gatttcagtg atgttatttg
     2401 tacctaatac agcagcaatt tcaagtgtac gtgccatgat agctgagtgg cttgtacgtc
     2461 caccaatgtt ggttacaaaa gcttttacaa agtttttgtc caattgagct gtatctgaag
     2521 gagtcaagtc atgcgcaatc acaatcactt cttcattgat agaagctggg tttggcaatt
     2581 ttttaccaag aaggtttgcc aatacacgtt ttgtcacgtc gcggatatcc gctgcgcgtt
     2641 cttgcatgta tgggttgtct tccatgcctt caaagatagt gataaacata tctgtaactt
     2701 ctttcagacc tgcttctgca ttcactttct tcgcacggat agtttccttg atttggctga
     2761 tcatttctgg gtcagcaaga accattaagt gagcatcaaa aacttgagct gcttcttcac
     2821 cgagcgtacc tactgctttc tcgcgaataa cagaaagctc gtcttgtgat gcctgtagag
     2881 cggcatcaag gcgagcttct tctgcgtttg tatcttcgac tgtaatagtc tcaaatgaca
     2941 aatccggctg aacgagtaga tatgcttttg caactgcaac accgtcagat gctgcgattc
     3001 ctttaagcat ttctgtcatt tcccttatgc caatccttct ttttccattg tttctgagat
     3061 tgcagcgata gcgtcatctg catctgcacc ttcagctgag atagttacgt cagcaccttg
     3121 gccaacacca agactcataa cacccataat tgatttaagg ttaactgatt tacctttgta
     3181 ctcaagagtg atatctgaag caaatttgct agcagtttgt accaacaatg ttgctggacg
     3241 tgcgtgaata cctgtttctg ccactacgtg gaaatcttta gaagccatag tttgactctc
     3301 cttttgttct ttcttttttt gagttatatg tgataaccct tacaatttag tattatacca
     3361 tcttctagga tttttttcaa gcattttctg gattttcctt caatttcctt tcagataact
     3421 tgctgaaaat cttctatctt agagaacaaa acacaggata tagtttcttc aaaaacaatt
     3481 tataggataa tcattgctat ttcacaatac aaacactata tattgtgttt atatataaaa
     3541 acaa
//
LOCUS       DAVLGK010000093         3073 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLGK010000093 DAVLGK010000000
VERSION     DAVLGK010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3073
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.094"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VXE01_002175"
     CDS             complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VXE01_002175"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0751007.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKEPQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1400..2176
                     /gene="recX"
                     /locus_tag="VXE01_002176"
     CDS             1400..2176
                     /gene="recX"
                     /locus_tag="VXE01_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV0751008.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2265..2798
                     /locus_tag="VXE01_002177"
     CDS             2265..2798
                     /locus_tag="VXE01_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV0751009.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
BASE COUNT         1003 a          551 c          545 g          974 t
ORIGIN      
        1 ccttttttaa acttttttta ttaattttac aacagcttca gttcgagctg tatgtgggaa
       61 catatcgacc gactggatat aatgaagatc atagacttct actaagcgta ccaaatcacg
      121 agccaaggtc gaaacattac aagaaatata aaccattttt tctggtacat aagtaagaat
      181 agtatctaat aacttatcat ccagacctgt acgtggtggg tcaacaatca aagcatctgc
      241 tcggtagcct tccttgtacc aacgaggaat aatctcttct gccgttccag cttcataatg
      301 agtattgtca aatcccattc ttttagcatt tcgcttggca tcttcaatag cttctggaat
      361 aatatccata cctctgagtg tttttacttt ctttgcaaag gcaaatccaa tcgttccaac
      421 tccacaataa gcgtcaatca aatggtcttc tttatcaaca tccagcgctt ttactgcttc
      481 gctatagagg acttctgttt gctcaggatt tagttgataa aaagctcgag gggatagtga
      541 aaattcataa ttgagtacac cttcttgaat actctcttgc ccccagataa tctctgtctt
      601 ttcaccatat atctcactgg ttttagctgt atttgtatta acagctactg tcacaacttc
      661 tgggaaatct ttaaccaact cttttaccaa ttgagttaaa ttaagctggc ggtttgtaac
      721 aataataatc tgaacctgtc cggtctttct cgcgcgtcgg accataatag tacggacacc
      781 tagaactttt ctctcatccg tgattggaat ctggtgataa gtaagtaatt ctgctaagcg
      841 attagcaatc acttggggtt ccttatcttg taccaggcag tctttcaact ctactaaata
      901 gtgagagttt tgtgcatata agcccgcctt gacctgattt ttaaattttc gagtctgaaa
      961 ttgtaactta gctctgtaat attttggttc ctgcattcca atagttggac gaatttcata
     1021 attttcatat cctgcaggag caaatttttt cagcgcttga tgaagtaagt ccgtcttgaa
     1081 ctccagctgc ttatcataat gcaggtgcat gatttggcag cctccgcatt cattataaat
     1141 agtacaagat ggcacaattc gaaatttaga cttcttgttg accttcagta attttgcttc
     1201 aacaaagttg cgtctaatag aagtaatctg acaatagata tcttcgcctt tgagagctcc
     1261 tggtacaaag actaatgttt tttggtaaaa gccgattccc tcaccgttaa ttcccatgcg
     1321 cttgattttt aatggtattt tttgtttcac tttcagattc atacccctat cttatcacat
     1381 tttgagttat aatagagcta tgaaaatcac aaaacttgaa aagaaaaaaa gactctatct
     1441 gatggagctt gataatggcg acaaatgcta tatcaccgaa gatacaattg ttcgttttat
     1501 gttatcgaga gataaggtga taagcgaaga ggaattgaaa gagattcaag actttgctca
     1561 attttcttat ggtaagaatc tggccctcta ccacttatcc tttaaagcac gcactgaaaa
     1621 agaagtcaga gaatatctga aaaaatacga tattgatgaa aacatcgttt ctcaagttat
     1681 tgctaatctt aaagaagata agtggattaa tgatggtcag tacgcttatg ctatcatcaa
     1741 taccaatcaa ctttcaggag acaagggtcc ttatgtgctg actcagaaac tagctcaaaa
     1801 agggatttca aaatctacta tagaagagaa cttgaaagaa tttgattttt ctgaagttgc
     1861 tcaacgtgta gctaataaac tattgaaaaa atatgaggga aaacttccag ctcgtgccct
     1921 gcaagataag attatccaga acttgactaa caagggcttc tcttattctg atgctaaaat
     1981 tgcctttgac gacttagata gccaagttga ccaagaaacg actcaagaac tcatcttcaa
     2041 ggaacttgat aagcaatata ctaagtatgc tcgaaagtat gaaggatacg aactgaagca
     2101 gcgtttaact caagttttag cacgaaaggg ctacgatttt tcggatatag caagcgctct
     2161 tagagaatat ctttaatatt tccaagtgaa attcacagat tttaggtaat tttatggtac
     2221 aatagtaaat gataaactta taaattgtag aaagttggtt agttatgaag cttccaaaag
     2281 aaggcgactt tattacaatt caaagttata agcatgatgg gagtctccac cgaacttggc
     2341 gggacaccat ggtactaaaa acaacagaaa acgccattat tggtgtcaac gatcatacac
     2401 ttgttaccga aagtgatggt cgtcgttggg tcactcgaga accggctatt gtttactttc
     2461 acaagaaata ttggtttaat atcattgcca tgattcgtga taatggaact tcttactatt
     2521 gcaatatggc tagcccctac tatctggatg aagaagcact gaagtatatt gattacgatt
     2581 tggatgttaa aatttttaca gatggggaaa aacgtctctt ggacgttgaa gagtacgagc
     2641 gtcacaaacg caaaatgaat tattctgatg acttggatta tattttaaaa gaacatgtca
     2701 aaattcttgt tgattggatt aacaatggac gtggtccttt ctcagaagcc tatgtaaaca
     2761 tttggtacaa gcgctatgta gaactaaaga atcggtaaag ttgtcaaagg tcaggaacaa
     2821 aatcctgacc tttttttggt agtataaaat aaattgtgta aacacaaaaa ggaataaatc
     2881 tattatagca gagttacaac acattactag aaagagattt atgcaaaatt cgtaaaatat
     2941 ataaaacaaa tagatatact gttatttttt aatgtcttta ttccttgtaa gtttacaaca
     3001 aacttatatc gtttaataca aaaaatacga aaatgattag tataaaaaat acaggtcaac
     3061 ttcgtatcaa aaa
//
LOCUS       DAVLGK010000094         3070 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLGK010000094 DAVLGK010000000
VERSION     DAVLGK010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.095"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(147..2648)
                     /locus_tag="VXE01_002178"
     CDS             complement(147..2648)
                     /locus_tag="VXE01_002178"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV0751010.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGDVKEAAYTEDGLHVNSDFLDELNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
BASE COUNT          840 a          680 c          613 g          937 t
ORIGIN      
        1 atcatacttt cataagaagg ttcaaaaaat cctccagatt ctactctgaa ggattcctat
       61 cttatttcac aacaatgtta actaatttag ttggcttcaa tagtccagtg gactattgaa
      121 ggtggcagat agagctaata aactcgttat ttaacgacga tattaacgag tttattcggt
      181 accgcaatta ctttcacgat ttccttaccg tcaatttctg ctttgacttt ttcatcagct
      241 aaagcgattt cttgtaattc ttcacgtgat atatctttag caaccatgag tttggcacgg
      301 acttttcctt tgatttggac gacaatttca atttcatctt caaccaattt gctttcgtcc
      361 caagttggcc aagctacata agagattgac tcacctgttt ctgcgactgt ttgccagagt
      421 tcttctgcca agtgaggtgc aaatggtgca atcaattgaa taaagccttt ggcatagtca
      481 acataaagct tatcttcctt gttagcagca ttgacaaaga ccataagttg ggcaatagct
      541 gtgttgaatt tgagagactc aatttgctca gtaacagctt tgactgtttc gttgtaaacc
      601 ttgtcaagag caccattgtt ttccgcaagg atttctttac ttgtaatcaa acggtaaact
      661 cggtcaagga acttacggct tccttccaaa ccttcttctg accaagcaat cgaagcatcg
      721 agtggtccca taaacatttc ataaacacga agggtatcgg caccgtattg ttccaccaca
      781 tcgtctgggt taacaacgtt cttgagcgat ttagacatct tggctggcgc ttgctccaac
      841 tcttcccctg tttctacatg aaagaaggaa ccatcacgtt tttcaacctt gtcggttgcc
      901 acaagagcac cacggtggtc acggtagctt gttcccaaaa tcatcccttg gttaaagagt
      961 ttttggaatg gttccttagt cggaacaaca ccgaggtcat agaggaattt gtgccagaaa
     1021 cgagcgtaaa gcaagtgaag tacagcatgt tccgcaccac ccacgtagat atctactggc
     1081 aaccattgtt tgaggaggtc ctcatcagcc aatttctcag tattgtgtgg atcaatatag
     1141 cggaggtagt accaacttga accagcccat tgtggcatag tgttggtttc acgacgacct
     1201 ttgacaccat cttcacgagt cacttcaagc caatctgtca agttagctag tggactttca
     1261 ccagtacctg aaggacggat atccttggtt acaggcaaga caagcggcaa ttcagtttca
     1321 ggaacagctg ttgaagttcc atcttcccaa tgaatgattg gaattggctc accccagtaa
     1381 cgttgacggc taaagagcca gtcgcggaga cggtaggtaa ccttctcctg accacagcct
     1441 ttttcttcca accaagccac aatcttggca atagcgtctt ctttgttgag ttcatctagg
     1501 aagtctgaat tgacatgcag gccatcctct gtgtaggcag cttctttgac atctccacct
     1561 tcaagtactt cgacgattgg aaggtcaaat tgtttggcaa attcccagtc acgttggtcg
     1621 tgggcaggca cagccataac cgcacctgtt ccataactag caagaacata gtccgcaatc
     1681 cagattggca tttccttacc attgacaggg ttgatggcat aggcacctgt ccaaacacca
     1741 gttttttcct tagcaaggtc tgtacgagcc aagtcagact taaggctggc ttggtgttta
     1801 tagtctgcta cagcttctgc ttgctctgaa cttgtgatag cgtctactaa ttcatgttca
     1861 ggagccaaga cagtgaaagt cgcaccgaaa agtgtgtctg gacgagtagt aaagactgta
     1921 aattccttgt ctgttccttt tactttgaaa gttacattgg caccagttga tttaccaatc
     1981 cagttgcgtt gcatatcctt gatagactct gaccaatcta gttcatctaa gtcattgagc
     2041 aagcgctctg cgtaagccgt gattttgagc atccattggc gcattggttt gcggacaact
     2101 ggatagcctc cacgctcaga agttccgtca ggaagcactt cttcattggc aatggcagtt
     2161 cccaattcct caacccagtt tactggcact tcagcttcat aggccaagcc tttttcgtaa
     2221 agcttggtga aaatccattg agtccacttg tagtagtttg gatctgttgt gttgacttca
     2281 cgatcccagt cataagaaaa tccaagcgca ttgatttgac gtttgaagtt ggcaatgttt
     2341 tccgctgtaa attctgctgg gtcattacca gtatccatag cgtattgctc tgcaggtaaa
     2401 ccaaaagcat cccaacccat tgggtgaagg acattgtagc cttgcgcacg tttgtaacga
     2461 ctgaggatat cggttgcagt ataaccttct gggtgtccta catgcagacc agctccagac
     2521 ggataaggga acatatcaag cgcataaaac ttaggttttg atgcatctgt tcctgtctta
     2581 aatgtatgat gttctgccca gtagccctgc cacttaggct caatttcttt atgattataa
     2641 aaactcatgg tctctctcca attttgtgat gttactatta taccattttt gagggaattt
     2701 gaaatgtgtt taaagaaaaa actgtatact gtatctcatt aattttgatg actatgaatt
     2761 gctctatctc ccacttttta tcccattgtt atgcagtaaa tcaaggagta agtcaagaag
     2821 cttatctcgt atagcacaaa atacttactt tagaccgaag ataaaactgg aatgctaatt
     2881 aatgtattca caataaatag ccgacaacct atgtcgcttt ttgatttatg aagaacgtat
     2941 agtggactga atctgaaata gtacgaaaca attgctaaaa cacttataga aattaatttt
     3001 actttcccaa tcgatttgtt ctcatcttat ttcaatctgc tatagaattc aatacgagga
     3061 tcaataaaag
//
LOCUS       DAVLGK010000095         2982 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLGK010000095 DAVLGK010000000
VERSION     DAVLGK010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2982
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.096"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            452..691
                     /locus_tag="VXE01_002179"
     CDS             452..691
                     /locus_tag="VXE01_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751011.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYPITSPIIGLVIGYNK
                     INLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            848..1906
                     /locus_tag="VXE01_002180"
     CDS             848..1906
                     /locus_tag="VXE01_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751012.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPFSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSDVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            2220..>2982
                     /locus_tag="VXE01_002181"
     CDS             2220..>2982
                     /locus_tag="VXE01_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751013.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIK"
BASE COUNT          970 a          382 c          509 g         1121 t
ORIGIN      
        1 tcattagatt ctattgaaga tataaattaa aaacgaggct gggaaaaaac tcaatttgaa
       61 aatgagattg agtaaatctt tctatctata taacgtatat catcaatatt tttgaacacc
      121 tgataatatg catttttctt attttaaaga ttttttgcct ttcttcattt cttgaatgaa
      181 ttggagagat gactttattt aggtgtttga cattactata gataggattt agcagtacta
      241 atatgaactc atattatagg tgcagactta aattttggaa gcaagctaaa ggatatctta
      301 tctaggtaac taagtgttat aacaagatat attggtggag ttagtatggc aactattact
      361 aatgctctta atattgcggc tactgttgct gaagtcttct cattaggagg agccattgca
      421 tatggtttag atatcgtaga cggtaaattt gatgggtatt tatgggcgta aaactatagc
      481 tatgaaacat ttttttgcag gaattggtga aattcatttt ttgttatttt tattatatcc
      541 aatcactagt ccaattattg gactagtgat tggatataat aaaataaatc taataaattc
      601 tattattata gctcttggta tgatattggc attaattttg gtattatcaa gagtgtatag
      661 aaaatatttt tatagagacg atgatgacta aagtttttat caataatttg ggctccttgt
      721 caactgtagt gggttgaata aaagctaacg tctggggaag ggtttaaagc tttgctttat
      781 caaatattga cttacagagt tgctctattg tattgatgca ttcttagtaa ataatatggt
      841 gttttgaatg aaagatgatc agaaatattt attagcggga ctttattcgc ttctagttgc
      901 aatattttat tttccattga ttgattccaa ggggattttt gtaagtatat tgatggcggt
      961 tttactttta tatttaatat acttcattgc aacagtcatt catattgtga taattaagtt
     1021 tataagaaaa aaatctttta agtatttggt tctatatcca tttacttatg atgggagctg
     1081 gagatttcaa cctataaact tactctactt tccagaaatg gtgagagatg tcattccgat
     1141 taatttagtt caagaatatt gccaaggaca accttacgga ctgttaaaaa agatgctgaa
     1201 aagaattcga ttgtcacgag agatatcttt actcctggct accattatcg tctatttttt
     1261 tacgcataga attctacctt tttcagtatt tacgttcatg ttttcttata tattgctatt
     1321 tgtacaatct tatttgggtg gtaataccgc ttggattgga aatagaagat taataataga
     1381 tgatgaattt gaaaaaatct tgctttcaaa aagttatata aaagaaatat catctgcacg
     1441 atactcggaa tacttgacat gtgaatacaa aaaccttaca ccaatcatat tgttagctat
     1501 ttttgaaaat ttgcttgact cctacttgct tcagaatcag agtgatgttg acttagatat
     1561 tttttataaa gttttacctt tgctttataa agaaaaatat actatgggat tcaattactt
     1621 tgtaagttta aattatttac tatataaggt tggatttttg ggaatcattt acgataatga
     1681 agcattaaga gatttgtcaa aacaatattt aaacaaaaat atttcggaat tacaagatgg
     1741 ttctttcgag ggcggtatac aagatgctgt tgcctctaaa caaatagtag ttataaatga
     1801 atttatagct tgtttaaatt ccagatgcgt gccatcccaa tatgatagat ttttttataa
     1861 agatagacct tatatttttt ccagaaagag tcctattaag gggtgaaaat ttgttacatt
     1921 tggattaaca agtgtcctag ggattagaaa taactctagt atagctagat atttttgagt
     1981 aactagaaat atcattagtc tacccatatg attgccagaa aagatggctg atgaatctta
     2041 tttatactgt tgcagtaggc gttgtctagg ataaataagc tatcttgatg ggggagattg
     2101 gaataatttt agtagaaaca ttaaaggatt atggacaagt agcgcaggat taggtgatgc
     2161 aatgtgctaa gttggcttgg tgttagcagt agtattattt aacaatggaa agtagactaa
     2221 tgaaaaataa gcgttatttt tttgacacaa ttttaataat tttactgctt ataagcacga
     2281 tattttgtgt cagcccagta tttataaaat tggacatctt aggaactccc tctcatgcca
     2341 tcttaacctt tgtattggcg ataccgttat tctatatttt gtctcaatgc ttacatactt
     2401 tgctattact agtttcctca atcttttgta aattaagacc aatttatttt tattttatat
     2461 ttgtgatcat tataggagct aggaaatact atcgaattct ctttcaccaa ctaatgggat
     2521 ttagtccagg aatagcagtg ttttataagg agagtcaaac aactaagaat ctgtttaaat
     2581 tttactactt cttgtacttt acaacactaa tttcatacta ttttttcttt acttttgtgt
     2641 atgacaaatc gttgcttttg cctcttattc cattttctat tatcatagca ttagtacaaa
     2701 aactttatag aattgagaat caacaattat ttctgttaaa atcaaaggta ctaacaatac
     2761 tggaatctaa gagggattgt gagtttaatc ttcaggatta tcatgaaatt tggaaattgc
     2821 aatcaaaatc tgagttgcca tgcgtggctt tatcttatat cagtttgatc aagccatatc
     2881 tttcagagag cgtgcgtgaa caaattgatt tattagaagt taagcgattt aaaaaaataa
     2941 atcatccaat atcactttat ggtatgttgg atgttataaa at
//
LOCUS       DAVLGK010000096         2947 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLGK010000096 DAVLGK010000000
VERSION     DAVLGK010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2947
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.097"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..1233
                     /locus_tag="VXE01_002182"
     CDS             <1..1233
                     /locus_tag="VXE01_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0751014.1"
                     /translation="SSSGTADLYITEVDLYKGYKPRTWQPHTEDAVADANKKLEATQT
                     KMTQLAGSWVVENINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMVD
                     KLKTANFEAGSVTTTILEAEAVTAEKLKVDNALIKKLTATDAFIDQLTSKRIFSIKVE
                     SVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAGHGVRTAFWANW
                     GNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGI
                     ELGSKDVLGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKENITDTAVKALDK
                     INRLRMVAFDFIENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLI
                     KAIQELNQKIEKMEKTIA"
     gene            1327..1530
                     /locus_tag="VXE01_002183"
     CDS             1327..1530
                     /locus_tag="VXE01_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751015.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLDEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            1533..1883
                     /locus_tag="VXE01_002184"
     CDS             1533..1883
                     /locus_tag="VXE01_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751016.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTGEPKE"
     gene            1893..2309
                     /locus_tag="VXE01_002185"
     CDS             1893..2309
                     /locus_tag="VXE01_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEV0751017.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFAFLYSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            2313..2645
                     /locus_tag="VXE01_002186"
     CDS             2313..2645
                     /locus_tag="VXE01_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0751018.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVASETGFKGDEKLEQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            2649..>2947
                     /locus_tag="VXE01_002187"
     CDS             2649..>2947
                     /locus_tag="VXE01_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HEV0751019.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMT"
BASE COUNT          964 a          543 c          691 g          749 t
ORIGIN      
        1 tcatcatcag gaacagctga tttgtatatt acagaagttg acttgtacaa aggttataaa
       61 cctagaacat ggcaaccaca tacagaagat gcagtcgcag atgcgaataa gaagcttgaa
      121 gcaacgcaaa caaaaatgac tcaactagct ggctcatggg tagttgaaaa catcaactcg
      181 gctggagata tcatctctgg aatcaatctt ggcgccaatg gacataaccg ctttgttggg
      241 aaattgaccc acatcactgg agagaccctg attgacagag cagtcatcaa gtctgccatg
      301 gttgataagc tcaaaacggc caattttgaa gctggttcgg tcacgactac gatattagaa
      361 gctgaagcgg taactgctga gaagttgaaa gttgacaatg cgcttattaa aaaattaact
      421 gcaactgatg cttttattga ccaactgaca tctaaacgta tcttctctat taaggttgag
      481 tccgtcattt ctagctcaac cttcctagaa gcctatcaag gccgaatcgg tggattcaca
      541 cttggtcaat ttgaccaggg tggcggtcgc tggatttcag gtgtcaatca gttctctgtt
      601 ggtatgggga atggtgccgg gcatggagtc cggacagcct tctgggcgaa ctggggaaat
      661 aattggaact atgccggacc taaagcatgg aacgtcaata ctgatgggaa aatgtactgt
      721 aggaatgaag tcggttttta tgatcaagtg gatttttcga attcatcgag agcaaacttc
      781 tatgggaata ctactttttc tcgttctcct gtgttttcaa atggtatcga acttggaagt
      841 aaagatgtgc ttggtgatgg ctggaatccc aaaggaggaa ggaatgcggt tgtttggtgg
      901 aatcaggtcg gtagcggtag cgtgaagtat tggatggaac aaaaatcaga cagacgctta
      961 aaagagaaca tcacagatac agctgtgaaa gccttggata aaatcaacag attaagaatg
     1021 gttgcatttg atttcatcga aaataagaaa catgaggaga ttggtctaat agctcaagag
     1081 gctgaaacca tcgttccaag aattgtctca cgagatcctg agaatccaga tggctatcta
     1141 catatcgact ataccgcttt agttccttac ttaatcaagg ctattcaaga attaaatcaa
     1201 aaaatagaaa aaatggaaaa aacaatagca tgaataacaa catgttgacc aatatcgcac
     1261 ttaaagcaat tcaggagctt gctcttgaaa atagaaaacg aacacacaga ttggagaact
     1321 tagaaaatga acacagaaca gcttaaccaa gccttacaaa tgacaattag tgaaatgtca
     1381 acaacttcaa caaattcgat gattacaagt aatatcttga gtattcagtt ggatgagcaa
     1441 agggaagaga atcaaagact tcaagcacga gtggatgagc tggaagctct gcttgatgaa
     1501 caaactaaac cagcagacaa aggagaatag acatggcaga aacaattcaa aacacagata
     1561 acttgctaga ccttacaaaa atcacagaac catttgatct tgcgagcgct ttgcgctata
     1621 tgaaagaaaa tggagagttc attcgttgca agaatgtaag cgatgacttc tatatgtatc
     1681 gtgatgttca aaaacgtcct gtgatcgtaa atggccgtcg ccaactcaag gatgttgaaa
     1741 ccgtttgggc gttcaaccag tggggtggta caatcgcaac aatcaacgtc gccgttctgt
     1801 tgaatcatga attctatatc atgaaatttg atgcagaggg caatcctgac tggacggatc
     1861 caacgggaga acctaaagaa taggagatgt gtatgcaaat tgaatttttc aattttctaa
     1921 gaagtgtcgt acagactgaa gatggtttgg tcttgtacgc tctagcactg attgtctcaa
     1981 tggaaatcat tgattttgtg acagggacga ttgcggcgat tatcaatcct gacatcgagt
     2041 acaagagcaa aatcggcatt aacgggctcc ttcgtaagat ttcaggggtt ctcttactga
     2101 tgatcctcat tccggcgtcc gttttgttgc ctgaaaagac aggttttgca ttcttgtact
     2161 caatctatct cgggtacatc gcatttactt ttcaatcact cattgaaaat taccgcaaat
     2221 taaaaggaaa tgttactctt tttcagccga ttgtaaaagt atttcagcga ttacttgaaa
     2281 aagatgatga tacgaaaaaa ggagaataac aaatgcaaca aattactgaa atcattacta
     2341 atggagcaat cagcatccta gtcattttag caggggtggt agttagggca gtcaaggact
     2401 acctggttca aaaaggtgga gaaaagacca tcaaaatcgt tgaaatcttg gccaaaaacg
     2461 cagttaatgc cgtggagcag gttgcctcag agactggctt taaaggcgat gaaaagctgg
     2521 agcaggctcg tgctaaagtc cgtgctgagc ttacaaaata caatattagt atgactgaca
     2581 aagacttaga caccttcgta gagtcagcag tgaagcagat gaatgacgca tggaaaggac
     2641 gatagggaat ggatatcgat agaaacagac tacgtacagg cttgccacag gttggggtgc
     2701 agccttatcg acaagtacat gctcactcaa caggtaaccg caactcaacc gtacagaatg
     2761 aagcggatta tcactggcgg aaagacccag aattaggttt tttctcgcac gttgttggga
     2821 acggtcgcat catgcaggta ggacctgtga acaacggaag ttgggatgtt gggggcggtt
     2881 ggaatgctga gagttacgca gcggttgaac tgattgaaag ccattcaact aaagaagagt
     2941 tcatgac
//
LOCUS       DAVLGK010000097         2401 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLGK010000097 DAVLGK010000000
VERSION     DAVLGK010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2401
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.098"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..245)
                     /locus_tag="VXE01_002188"
     CDS             complement(<1..245)
                     /locus_tag="VXE01_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751020.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLVNSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNR"
     gene            complement(303..1016)
                     /locus_tag="VXE01_002189"
     CDS             complement(303..1016)
                     /locus_tag="VXE01_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV0751021.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1506..1613)
                     /locus_tag="VXE01_002190"
                     /pseudo
     CDS             complement(1506..1613)
                     /locus_tag="VXE01_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2035..>2401)
                     /locus_tag="VXE01_002191"
     CDS             complement(2035..>2401)
                     /locus_tag="VXE01_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV0751022.1"
                     /translation="RNKNGQADTNQTEKPQTEKPEEETPREEKPQSEKPESPKPTEEP
                     EEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQD
                     NNTIMAEAEKLLALLKESK"
BASE COUNT          736 a          462 c          378 g          825 t
ORIGIN      
        1 cgattagtaa gataattcgg aaatatattt cctattactc taagattatc tacttgtgaa
       61 tcccttctcc caatataatc cccttctttg actaatgatg gagatttcca agtaaaaatt
      121 aaatcgccag agaaattttt cttatcaaaa aacttaaaaa gagattgata aatactattt
      181 actaattgac aagtgtcaga tgtaaattca taattaacag cttcattaaa atcaacttca
      241 gacatttcaa tgtactcttc aatagtaata ttagcttttt tgtagtcatt agctcgtctc
      301 ctttaaaatg tgatcttttc aagaatattt ttatctaaac aatccagcaa gtcttggtaa
      361 gaatagactt cgtaagtcgg ctgggcttgt gtgtgatttt cgaggtgatg aggattatac
      421 cagatagtgt caatccccgc attattgcca ccttgaatgt cggcggttag agaatctcca
      481 atcatcagcg tcttttcttt actaaatcca gcaatttgct ggccaatctt ttcataaaaa
      541 agagcatccg gcttttgagt ttgcaactgt tctgagataa agacttgatt gaaataaggt
      601 gctagaccag attgagccaa acgtcctgtc tgaatggcag taatgccatt tgtcgcagca
      661 tacaagttat aatcacgctc aatgaggctg tccaagagat catgagcgcc cgatagtgtt
      721 tgtccctgct gggcgaggta aaattggtaa cgctgggcaa gaaaactacc gtctttttcc
      781 tgtccaaaat gagcaaataa acgagaaaag cgcgtgttaa ccagctcttg tttactgatt
      841 ttcttcagct ccaagtcttt ccagagagcc ttgttcatag gaacgtaata atctttataa
      901 gcctgaatat ccgcaactcc ttcttctttt agaagttggg tcaaagccac atcctcagca
      961 gcatcaaaat caagaagagt gtggtcgagg tcgaagagta gaaatttgta gaacaatttg
     1021 aggttttcct ttctgaaaat tcattaagaa cattatatca taaagcacct catacaatta
     1081 actaatttaa tcacttaaaa aaaattcgaa cactttctat acaactgaca gctcaaatct
     1141 ttcagaatag aacaatacta actatcgaac accccgtctt cataaataca tatgtaattc
     1201 taggcctaga attcctataa actaaatgct ttcatactct tccaagtaat tgattgcctt
     1261 aaattttaat ttttgaaggt ttctaaagct agaatagccc catcacaatc agttttgatt
     1321 gattcacaat ttagaaacac tatagtttca ctcctgttaa aataaaaagg aactgcataa
     1381 agcaatccct ttctgatttt gaaatcattt acttaacatt ttatagttga gataatcaat
     1441 agcttatcta taaaaagagt tatagtaaaa ttccttattt attgatttca agctccgcta
     1501 actgtataag taatcggaac atctttagct actttactaa tcagttcaac aacaccttct
     1561 gcaatgtgtt tggaatgtga aacgataaca agaccaatac caatactttc catcaaacca
     1621 ccccagtttc taaaatagca gtaaagagta atcctgatga gaatgatcca ggatcaatat
     1681 gtccaagaaa ccacatgctc ctaagacaag agctaacaga ctggccatca ataatagtat
     1741 tgttcttttt ttcatcatta ctccttaact agtgtttaac tgattaatta gccagtaaat
     1801 agtttatctt tatttacact atctgttaag atatagtaaa atgaaataag aacaggacag
     1861 tcaaatcgat ttctaacaat gttttagaag tagaggtata ctattctagt ttcaatctac
     1921 tatattttgc acattttcat gaaaaaaatg agaactagaa ctcacattct gctctcattt
     1981 ttcgttttcc cgttctccta tcctgttttt aggagttaga aaatgctgct acctttactt
     2041 actctccttt aataaagcca atagtttttc agcttctgcc ataatagtat tgttgtcctg
     2101 ggtgccaaat agtaaattat tttttaatcc tgtgagagtc tctttggcat tggacttgat
     2161 aattggatcc tggatttttc caagtaaatc ttcagcctct ctcagttttt cttcaacctt
     2221 ttcagtctcg acctgaggtt cttctgattc ctctggtgat tcttcttctg gttcctctgt
     2281 tggttttgga gactctggtt tctcgctttg cggtttctct tctcgaggag tttcttcctc
     2341 aggtttttct gtctgaggtt tctccgtttg attggtatca gcttgaccat ttttgtttct
     2401 t
//
LOCUS       DAVLGK010000098         2245 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLGK010000098 DAVLGK010000000
VERSION     DAVLGK010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2245
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.099"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            69..251
                     /locus_tag="VXE01_002192"
     CDS             69..251
                     /locus_tag="VXE01_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0751023.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            261..611
                     /locus_tag="VXE01_002193"
     CDS             261..611
                     /locus_tag="VXE01_002193"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0751024.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEHLRAVTGID
                     LLSILTDIANKKQG"
     gene            619..1809
                     /locus_tag="VXE01_002194"
     CDS             619..1809
                     /locus_tag="VXE01_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0751025.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
BASE COUNT          905 a          305 c          344 g          691 t
ORIGIN      
        1 aaatcgaaaa attagctaag aaatattctg ataacttaaa catcaaagtt caagagagag
       61 ttcgtgaaat ggcaaatgat aataagagcc attatttgat atacagagtt ttaggtattt
      121 catttgaaga aggagaaaat atcgatttgt atcaaaataa aggtcgtttt ttatacaaat
      181 atgctggttc atttttagaa gaagctgcag tactatcctt taacgaaaaa tttggtacag
      241 aaaatactta aaaagttaac attcctaatt ctgaaagtac aaaacctaag acttttgaaa
      301 ttgattgttt agtcggagaa aaacacgcat acgaaataaa atggtgggat gcaactacag
      361 atggagacca tataactaaa gaacacacta gaataaaagt tattcataac aaaggatata
      421 taccaattcg gttaatgttc tactatccaa atagaactca agctataaaa attcagcaaa
      481 ctttagaaac attgtataac ggtattggag ggaaatatta tggagattct gcctgggaac
      541 atttaagagc agtgaccggt attgatttac ttagtattct aacagatatt gcaaataaaa
      601 aacaggggta aaatcaaaat gacagtatta aaaggagata acttagaaat attaaaaact
      661 attgaatcct caagtattga tttaatctat atggaccctc ctttctttac acagaaaacc
      721 caaaaattat ctaataacaa aaatattatg tattcattcg aagatacgtg gacttcgatt
      781 gaggattaca aagaattttt gtctgtaaga ttagaagaat gcaaaagagt gctaaaaaat
      841 agtggcagta ttttcgttca ttgtgataaa attgcaaatc atcatattag attaatttta
      901 gataatatct ttggagcaga tatgtttcaa agcgaaatta tatggaacta taaacggtgg
      961 tctaattcaa aaaagggatt attgaacaat catcaaaaca tttactttta ttcaaagtca
     1021 aaagatttta aatttaatac aatttttaca gagtattctt ctactacaaa tatcgaccaa
     1081 atactagtgg aacgaaaacg agatggaaac tctaaaacta tatataaggt tgataataat
     1141 ggtaactata ttctagcaaa agagaaaaat ggagttcccc tttcagatgt ttggaatata
     1201 ccatttctta atccaaaagc taaagaaaga gtaggttatc ctacacaaaa acctattctg
     1261 ttattagaac aaattataaa gattgctact gataaaaatg atatagtttt agacccgttc
     1321 tgtggaagtg gaactacttt agtagcctcc aagattttga atagaaatta tatggggatt
     1381 gatttatctg aggaagctat caatataact cagcaacgtc tggaaaatgt tataaaaaca
     1441 agttcaaatt tattgaataa aggaatcgaa gcatatagaa ccaaaactga ggaagaggaa
     1501 aacattctta aattattaca ggcaaaaatt gttcaaagaa ataaaggaat tgatggtttt
     1561 ttacctaaac attttcaaaa aaaaccgata cctataaaaa ttcaaaaaaa taatgaatgt
     1621 ctgaatgaga gtatctcttt attacagaat gctataaact ccaaaaaact tgattttgga
     1681 gtagttataa aaactcattc agataattta ttatttgatt ttgatacgat tcctgaaaat
     1741 ataatagtag ttgaccattt tgaacttaca atcgaaaaat ggttaagtaa aagtcaacag
     1801 ttactatagt ttgcaaatta tttacagaaa gaacaaaaaa tgctctgaaa cactgatttc
     1861 aaggcatttt ttgttagttt aaaattactc ccattcttct tttccaaaca tacaatatat
     1921 ccaaaaccat tcaaaatact agattctatt ttttataata tcactaaatc cacctaatta
     1981 taggacgttt tcagattttt agtcccgtcc cagtcccagt accggagaaa tattgtttta
     2041 atataatatc tctttttgtc ttctaagctc ttaaaagcaa aagaacaagt aaagagtcaa
     2101 gacaaggata aaaagtccat attagggcaa ataaaaagct ttaagacaga tgacaaatct
     2161 aagtcaaata agaaagacca tagcaaaggt gcagagagat aaatattggc ggtcttcgga
     2221 ctgcctttat ttttttatcc atttt
//
LOCUS       DAVLGK010000099         2127 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLGK010000099 DAVLGK010000000
VERSION     DAVLGK010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2127
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.100"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..201
                     /locus_tag="VXE01_002195"
     CDS             <1..201
                     /locus_tag="VXE01_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEV0751026.1"
                     /translation="NANGSMATGWLKDGDTWYYLEASGAMKESQWFKVSDKWYYVNGS
                     GALAVNTTVGGYRVNANGKWVN"
     gene            541..>2127
                     /gene="pspC"
                     /locus_tag="VXE01_002196"
     CDS             541..>2127
                     /gene="pspC"
                     /locus_tag="VXE01_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     LPXTG-anchored form"
                     /protein_id="HEV0751027.1"
                     /translation="MFKSNHERRMRYSIRKFSVGVASVAVASLFMGSVVHATEREGST
                     QAATSSKMANESQIERRKAAEQAIVSLSGYMTSLLNDGLDTSDSRFEELLKRAKGIVE
                     EYRKKIDGASDREKIEKLQQEGQTKLDELVDKFKKGLSSSEQNGHATPKDPSRNDGVQ
                     GDDSSVGQGEQPGASNQKNPESVPPTASGETDSPTKPKTSNDSVNSLERELKEVKETA
                     KTTLNTYMLTRLKQENPGVFWFADLLRESKESVEKYKRMFDEASSKENVENLVKEAKQ
                     EIEALVVKHKGREIDLERTKAKTVIAKYLTGLLDDIKKNLKKEQHINTVELIKKLGDI
                     KRTYLYKLDESTQKAQLQELVTESQSKLDEAFSKFKNGLSSSSSSGSSTKPETPQPEK
                     PEHQKPTTPAPDTKPSPQPEGKKPSVPDINQEKEKAKLAVATYMSKILDDIQKHHLQK
                     EKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQD
                     TPKEPGNKKPSAPKPGMQPSP"
BASE COUNT          804 a          359 c          439 g          525 t
ORIGIN      
        1 aatgctaacg gttcgatggc aacaggttgg ctgaaagatg gagatacatg gtactatctt
       61 gaagcatcag gggctatgaa agaaagccaa tggttcaaag tatcagacaa atggtactat
      121 gtcaatggct caggtgccct tgcagtcaac acaactgtag gtggctatag agtcaatgcc
      181 aatggtaaat gggtaaacta aacctaatgt aactcgttaa tgctggcttc ctgtaagaac
      241 tctttaaagt attccctaca aataccatat cctttcagta gatactatac ccttgtagga
      301 agtttagatt aaaaaataac tctgtaatct ctagctggat ttatggcgct agagactacg
      361 gagtttaatt tctgttgaat tctagtttca ttagaatagc agaggaagaa aaattattgc
      421 aggaagttat tattccaaat ggaagaataa aaggatagcg aaaataatgt agcaaatttc
      481 atatacaatt catattagca ggatatactg tagttaatta aaattatgga gaatatagac
      541 atgtttaaat caaatcatga gcgaagaatg cgttattcca ttcgtaaatt tagtgtagga
      601 gtagctagcg tagctgttgc cagtcttttt atgggaagtg ttgtacatgc gacagagaga
      661 gagggaagta cccaagcagc cacttcttct aagatggcaa atgaaagtca gatagaacgt
      721 aggaaagctg ctgaacaagc tatcgttagt ttgtctggtt atatgactag tcttctaaat
      781 gatggattag atacttctga ttctagattt gaagagcttc tcaagcgagc taagggaatt
      841 gtagaagagt accggaagaa aattgatgga gcttctgata gagaaaaaat agagaaactg
      901 cagcaagagg gacaaacgaa gctagatgaa ttggtagaca aatttaaaaa agggttgtcc
      961 agctctgagc aaaatggtca tgctactcct aaggatccct ctcgaaatga tggtgtacag
     1021 ggagatgatt cttcagtagg gcaaggagaa cagccaggcg catctaatca aaaaaatcca
     1081 gaatctgtac caccaacagc atctggtgag acggattccc ctacaaaacc aaagacttcg
     1141 aatgattcag tgaattctct ggagagagag cttaaagaag ttaaagaaac tgctaaaaca
     1201 actttgaaca cttatatgct tactcgttta aaacaggaga atccaggagt tttttggttt
     1261 gcagatcttt taagagaatc caaagaatct gtagagaagt ataaaaggat gtttgatgag
     1321 gcttcgagta aagaaaacgt ggaaaacttg gtaaaagaag ctaaacagga gatagaagct
     1381 ctagtcgtta aacataaggg gcgagaaatt gacttagaac gaacgaaagc aaaaaccgta
     1441 attgctaaat atttaacagg attattagat gacatcaaga aaaatttaaa aaaagagcaa
     1501 catatcaata ctgtagagct aattaaaaag ctgggagaca ttaagcgaac gtatttgtat
     1561 aaattagatg aatcaaccca aaaagcccaa ctacaggaac tggtcacaga aagtcaatca
     1621 aaactagatg aagctttttc taaatttaaa aatggcttat cttcttcgtc aagttcagga
     1681 tcctccacta aaccagaaac tccgcagccg gaaaaaccag agcatcaaaa accaacaact
     1741 ccagctccgg ataccaaacc aagccctcaa ccagaaggca agaaaccaag cgtaccagac
     1801 attaatcagg aaaaagaaaa agctaagctt gctgtagcaa cctacatgag caagatttta
     1861 gatgatatac aaaaacatca tctgcagaaa gaaaaacatc gtcagattgt tgctcttatt
     1921 aaggagcttg atgagcttaa aaagcaagct ctttctgaaa ttgataatgt aaataccaaa
     1981 gtagaaattg aaaatacagt ccacaagata tttgcagaca tggatgcagt tgtgactaaa
     2041 ttcaaaaaag gcttaactca ggacacacca aaagaaccag gtaacaaaaa accatctgct
     2101 ccaaaaccag gtatgcaacc aagtcct
//
LOCUS       DAVLGK010000100         2083 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLGK010000100 DAVLGK010000000
VERSION     DAVLGK010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.101"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            20..1636
                     /locus_tag="VXE01_002197"
     CDS             20..1636
                     /locus_tag="VXE01_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0751028.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          739 a          243 c          382 g          719 t
ORIGIN      
        1 tagaaagtga gaaactattg tgtatactat tataaaatca aatataaaaa aatttagttt
       61 attaacgata tttattgttg ctggtcaatt attgctaatt tatgcagcaa ctattaatgc
      121 tctggtgttg aatgaattaa ttgcgatgaa tttagagcgg tttttgaaat tgtcaatcta
      181 ccaaatgatt gtctggtgtg ggataatatt ccttgactgg gtagtgaaaa attatcaggt
      241 tgaagtgatc caagagttta atctagagat tcgaaataga gttgccacag acatctctaa
      301 ctctacctat caagaatttc atagtaaatc atcaggaaca tatctttcgt ggctaaataa
      361 tgatgttcag actttaaatg atcaggcttt taaacaactt tttttagtaa taaaaggaat
      421 ttctggtact atatttgcag ttgtgactct taatcactat cattggtcat tgactgtagc
      481 caccttgttt tcattaatga ttatgctact tgtaccaaaa atctttgcat cgaaaatgcg
      541 agaagttagt ctaaatttaa ctaaccaaaa tgaagctttt ttaaaatcta gtgagactat
      601 attgaatgga tttgatgtgt tagcgtcctt gaatctttta tatgtattgc ctaagaaaat
      661 taaagaagca ggaattttat taaagatggt tatacaaaga aagacaactg tagaaacgtt
      721 agcaggcgct attagcttct ttctcaatat tttttttcag atatctctcg tttttttaac
      781 aggctatctt gcaataaaag gaatagtgaa aattggtact attgaagcaa taggagcact
      841 aacaggtgtt atttttacag cgctaggtga attaggaggt caattatcct ctattattgg
      901 tacgaagcct atttttttaa aattgtattc aattaatcca attgagtcaa ataaaatgaa
      961 tgatatcgaa ccaaatgagg tgaatagaga ttttccgtta tatgaagcaa aaaatatttg
     1021 ctataagtat ggagataaag aaatattaaa aaacttaaat ttttgttttc aacgtaatga
     1081 aaagtattta attttaggtg aaagtggaag cgggaaatct acattattaa aattattgaa
     1141 tggctttttg agagattata gtggagaatt gcgattctgc ggggatgata taaaaaaaac
     1201 ctcctattta aatatggttt cgaatgttct atatgtagat caaaaagctt atttgtttga
     1261 aggtacgatt agagataata ttttattgga agaaaattat actgatgaag aaatactaca
     1321 gtctttagag caagttggtt tgagtgtaaa agattttcct aataacattt tagattatta
     1381 tgttggtgat gatgggagat tactgtcagg agggcagaaa caaaaaatta ctttagctag
     1441 agggctaatt agaaataaga aaatagtatt aattgacgag ggaacttctg ctatcgatag
     1501 gagaacttcg ttagcgattg aacgtaagat attagataga gaggatttga ctgtcattat
     1561 tgttacccat gctccgcatc cggaacttaa acaatatttt actaagatat atcaatttcc
     1621 aaaggatttt atttaagaat ataggggagg gaaacatgag attctattgt gaagcttatg
     1681 aggtaattac tgaagagaaa aaagtatact ttaatgatat tgagttagaa gttaagtatt
     1741 cctctgtcga agaattgttt ataatatgtg agaaattatt agataagaaa aaagtatcat
     1801 ttttttatgt agatgagaaa cccttaaggt atctgttatt tgactatata tttctactag
     1861 ttctagctaa aaaaaatatc ccaatcttat gaactgcacc ccaaaagtta gatttattct
     1921 gtctaacttt tggggtgcag ttcattttgc atagttttgg cattcatcct agatatccat
     1981 ataaaatgtc tgagattgtt gaaatgtcta aaaaaatatc agatctaaac gataaaaaag
     2041 aatttcacaa aaagaactgt gagttgaggt ttcaagatag tgt
//
LOCUS       DAVLGK010000101         1912 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLGK010000101 DAVLGK010000000
VERSION     DAVLGK010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.102"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(1..1016)
                     /locus_tag="VXE01_002198"
                     /pseudo
     CDS             complement(1..1016)
                     /locus_tag="VXE01_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            complement(1029..1778)
                     /locus_tag="VXE01_002199"
     CDS             complement(1029..1778)
                     /locus_tag="VXE01_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV0751029.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFQYVSDSSMVGYMGKTKELKMYQEELDKKHYIDRISSISCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          663 a          347 c          212 g          690 t
ORIGIN      
        1 tcatatacta aaatttttat accgacaatc aatagttcat taattatact taaaatagct
       61 gactctttgt aattatctga attatatttc atccccaatt tatatattcc tactatcttt
      121 ggctttcgtt ccaatatttg tttaactatg aactgttttc tatttgtgtt tgaaatatca
      181 atcgcttcta tcactggggc atttatttct ataaattctt tttttaattg tttagtatct
      241 ttgggaagac aatatcctcc aaattcaaaa gaaggattat tataaaaatt tccaattctt
      301 ggatctaaac aaacaccttt tattacaact tcagcattta aacttctcct ctcagcaaaa
      361 aaatctagtt cattaaaaaa agcaacacgg agagctaaga atgtgttaga aaaaagctta
      421 attgcttctg cttcagtagg agaaactaac ataacatttt taatattggc agtactatga
      481 gtactaatcg aaaggaacaa ctctgcaatt tttcttcctt caactgtctc atctccaaca
      541 actatgcgac ttggatataa attatcatat atagaacaac cttctctcaa aaattcaggg
      601 acaaaaatga tattttttgt atcaaacagc ctttttaatt tgtttgaaaa gccgatcgga
      661 actgttgact ttcaaataat ctttccatta ggttttaccc tcagaatctt cgataccgtt
      721 tgttcgattt catatgtatt aaaactacca attttctcat cataatctgt cggaagcgca
      781 ataatataat aatcaatatt atttttaatt tcagaaaatg tatcaaaaaa agtaatattt
      841 aagttattct cgcaaaaaaa cttcataagc tcttcatttt tagatggaag aatgtccttt
      901 tttaaattat ttatttttac agaatctata tcatatgcaa caactttata tttagatgca
      961 aatagtaacg cgtaggccag cccaacatgc cccaaaccaa ttactgctat attcataaaa
     1021 ctacttcctt atttcttaat ccaaaatcta atagaataag ctgccccatt ccttaaatac
     1081 aactctttaa tattgtttaa aagtttttca actgatttcc agattatcaa aatctgagat
     1141 ttatagcacg atattgatga tattctatca atataatgtt ttttatcaag ttcctcttga
     1201 tacattttta attctttagt ttttcccata taaccaacca tactactatc acttacatat
     1261 tggaagtcct cataatatat tactttataa cgcataaatt caagcgccct tccaatacta
     1321 ttcacaaaaa catgatcaac atggtcacca agtgaaagcg gacaatatac gacacatttg
     1381 tcgtctaaat gcattaacag ctcttttatg atatcattct ttaatgtgtc ctcatttttt
     1441 aattcactat agatatgacg gtatagaaaa ttgccatttc tatctttcct atagagacat
     1501 tcatagtacg ataagtgtct aaaatcacat tgtagacgtt cacaagctaa cctgtcttct
     1561 ttcttccttt cttcaatcgg atatttccca aggttacaca acttatgaaa ttgcttagca
     1621 gagggctgta gctgttggct caaagggtaa ccagaaaata tagtaataac aagtacaatt
     1681 tctccttctg aagttaattt tgaaatataa tcaccacagg aaaaaattgc gtcatctaaa
     1741 tgtggagata aaaagatata cttagtattg ttactcataa ccattccctc tacaatttat
     1801 ctaaaaactc actaagtgtc tgattaaatt ccacatcatc aaaaaaattc accttattct
     1861 taataatgaa tatttcgtta aataaacata tatataaata tttcaatatc ct
//
LOCUS       DAVLGK010000102         1770 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLGK010000102 DAVLGK010000000
VERSION     DAVLGK010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1770
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.103"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..1588
                     /locus_tag="VXE01_002200"
     CDS             <1..1588
                     /locus_tag="VXE01_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0751030.1"
                     /translation="FDSDKIFEIVLELVRTEKLSNLYFISLTNEKEHSLFEYLTQKIK
                     NSTHIQVQERLQLLSLYPTLKNFAKYDCIFVDDEDLMHTLLDLFDWFTIIDRPKICLI
                     GSRVWFEKRNLFYIHLDYRILALNTAENLESRNSSIVPVKDGKQILIDQLFDGECDDI
                     YLLTVHSPMNKALEILSEKYKQISGKNIKIIEKRYDELLEMIESGDVSSSFDMIRMDM
                     AWLPTFGKKYFQEITSFRQTKSINQNISKSVSREYMYIDQKQYTFPLDVSSQILVYRK
                     DLFEDSFLQRRYFEKTKRKLTVPKSYQEFDELSEFFTLTENPFSPTLYGHSLALSSSV
                     RAACEFIPRFRERLAQSRMNLAVLPQVLTEYEKSYQFTEKSFNSSWNDFVTNLNSGKT
                     SMEIIFSNYTSPLFDGLNVSAQFEFATATIPGNTPVIGGGSIGISKYSNRVEECLNFI
                     NWLYSEEISILLTSLGGFLPSKYVMQNRMLQFQYPWLSSLEDTFSIGSRTKWYGFNTD
                     FRFEQMLGQELIESVKHRYG"
BASE COUNT          628 a          214 c          294 g          634 t
ORIGIN      
        1 ctttgatagt gataaaatat ttgagattgt acttgagttg gttcggactg aaaagctatc
       61 taatttatat tttatttcac ttactaatga aaaagaacat tctttatttg aatatttaac
      121 tcaaaaaata aaaaactcaa ctcatataca agtgcaagaa cgtttacaat tgttgtctct
      181 ataccctact ctaaaaaact ttgcaaagta tgattgtata tttgttgatg atgaagattt
      241 gatgcacacg ctattagact tatttgattg gtttactata attgatagac caaaaatatg
      301 tttgataggt tcacgtgttt ggttcgaaaa aagaaatctt ttttatatac atttagatta
      361 tagaatattg gcactcaata ctgccgaaaa tttagaaagt agaaatagtt caattgtacc
      421 agttaaagat ggcaaacaaa ttttaattga tcaattattt gatggagaat gtgatgatat
      481 ttatttactt actgtccatt caccaatgaa taaagcctta gaaattttat cagaaaagta
      541 taaacaaatt tctgggaaaa atattaaaat tatcgagaaa agatatgatg aacttttgga
      601 gatgattgag tctggcgatg tttcatccag ttttgatatg attagaatgg atatggcttg
      661 gcttccaaca tttgggaaaa agtattttca agagattaca agctttagac aaacaaaaag
      721 tattaatcaa aatatttcta agtcggtgtc tcgagagtat atgtatattg atcagaagca
      781 atatactttt ccattggatg ttagtagtca gattttagta tatagaaaag acttatttga
      841 agattcattt ttacaaagac gatactttga aaaaacaaaa agaaaattaa ctgtaccaaa
      901 aagttatcaa gagtttgatg agttaagtga attttttaca ttaacagaaa atccattttc
      961 acctacactt tatggccata gtttagcttt aagttcttca gtgagagcag catgtgaatt
     1021 tattcctcgg tttcgtgaga gattagcaca atctagaatg aatcttgctg tacttcctca
     1081 ggttttaact gagtatgaga aaagttatca gtttaccgaa aaatcattta attcttcgtg
     1141 gaacgatttc gttacgaact taaacagtgg taaaacttca atggaaataa ttttttcaaa
     1201 ttatactagt ccattatttg atggtctcaa tgtttctgct cagtttgagt ttgcaactgc
     1261 cactatacct ggtaatactc ctgtgatagg tggtggctca attggaattt ctaaatattc
     1321 aaatagagtg gaagaatgtc taaactttat taattggtta tattctgaag agatttctat
     1381 tttactaaca tctctgggtg gttttttacc atcaaagtat gtcatgcaaa ataggatgtt
     1441 acaatttcaa tatccatggt tatctagttt agaagataca tttagtattg ggagtagaac
     1501 aaaatggtac ggctttaata ctgattttag atttgagcag atgttagggc aagagttaat
     1561 agaaagtgtg aagcatagat atggataaat taatactaaa tttttattac tagtttattt
     1621 attattgttt aaaattaaag attcaagtaa acaccaatta tatttaaaat tattattttg
     1681 acatttttct attgcaaagt tattttatta gacttcctgc gaaacaaaat atggtatagt
     1741 agttctatga atgatgaagc aagtaaacaa
//
LOCUS       DAVLGK010000103         1497 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLGK010000103 DAVLGK010000000
VERSION     DAVLGK010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1497
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.104"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..998
                     /locus_tag="VXE01_002201"
     CDS             <1..998
                     /locus_tag="VXE01_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0751031.1"
                     /translation="NKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPP
                     LSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPN
                     DESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYGNKDETTSYPIYEIP
                     EAWRYIKFASLVNFRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLAL
                     KSKKIDISPKGTLLMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFL
                     PLISTLGDSKDAIKGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(946..1491)
                     /locus_tag="VXE01_002202"
     CDS             complement(946..1491)
                     /locus_tag="VXE01_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0751032.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          555 a          235 c          220 g          487 t
ORIGIN      
        1 taaataaaga ttacctattc tatattcttt catcaaatgt agtttattct caatttctat
       61 ctctaattag tggagctgtt gtgaaaaact tgaatagtga taaagttgct tctattctta
      121 tccctctccc cccactatcc gaacaacaac gcataataga agcaatcgaa tcagctttag
      181 aaaaagtaga tgaatatgct gaaagttata atagactaga acagctagat aaagaatttc
      241 cagataaact aaaaaaatct attcttcaat atgctatgca aggaaaatta gttgaacaag
      301 acccaaatga tgaatcagtc gaagttttac ttgaaaaaat acgagcagaa aaacaaaaac
      361 tctttgaaga aggcaagatt aaaaagaaag atttggacat ttctattgtt tcccaaggag
      421 atgataactc ttattatggg aacaaagacg aaacaacctc ttatcctata tatgaaatcc
      481 cagaagcatg gagatatatt aaatttgcta gcctagttaa cttcagaata ggaaaaactc
      541 ctccacgcag tgaagctact ttttggggaa ctgaaatacc ttgggtatct atatcagata
      601 tgcctatatc tggttatgta actaatacga gagaatctat ttctaaatta gcattaaaat
      661 caaagaaaat agacatttca cctaaaggaa ctttattaat gagttttaaa ttatctattg
      721 gaaaagttgc catattggat attcctgcca ctcataatga agccattata tcgatattcc
      781 cctatgctaa taaagaaaat attatcagag attacttaat gatatttttg ccacttatct
      841 ctactttagg tgattcaaaa gatgctataa aagggaaaac attaaatagt accagtatct
      901 ccgaattatt aatccctatt tctaatcatg aagagatgaa aagaatcatt tccaaagttg
      961 atttactttt tcaaaaagtt tctcaacttt ttgagtaata agttcctgtt cctcaaaagg
     1021 agctaacgga attaatagct cgcttagtgt agttttagga atattatata aagcttgacc
     1081 tgatagttta gttattgctt tcaattgttt ataaaataac ggagaggaca agttaaataa
     1141 tagaaatttt gaaataatct ctgaactttc gaatggtgtt aattggaaaa taaatccacc
     1201 agccacaaca ccatcatagt ctttatcgat tcttgcaaac tttccaatat gttctaaaga
     1261 ggttgataca ggtgttatta gctgattatg ttttaaataa acttgctcag aggagatgaa
     1321 ttgtgtatca atgtagtaat cattatccaa cagagaaaat tctaaaggct taatattacc
     1381 accacgtata attctaacac ctttattatt aatgcttaaa tcgcccttct tgtaagaaag
     1441 acctgtattt attgaaaaaa tatcttttat ttttataaca acccaattca taggtat
//
LOCUS       DAVLGK010000104         1484 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLGK010000104 DAVLGK010000000
VERSION     DAVLGK010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.105"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            217..1001
                     /locus_tag="VXE01_002203"
                     /pseudo
     CDS             217..1001
                     /locus_tag="VXE01_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1036..1245)
                     /locus_tag="VXE01_002204"
                     /pseudo
     CDS             complement(1036..1245)
                     /locus_tag="VXE01_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1411..1484)
                     /locus_tag="VXE01_002205"
     tRNA            complement(1411..1484)
                     /locus_tag="VXE01_002205"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1448..1450),aa:Asn,seq:gtt)
BASE COUNT          510 a          294 c          233 g          447 t
ORIGIN      
        1 tacacattca ctatcaattc ctgaattgtt aaaataccag cctcaacaag ataaaaatag
       61 gaaaagttga caaaatagaa acaaatttgc tacctaaatt tcaaacgatt aaagttctaa
      121 aaagaccgcc ttaaaacttt tgggtaaatc ctattagaac tataatattt atatatatgt
      181 attatggttc tgattttcta gtataaaaaa attcaaacta gaattcttct tagaaaaggc
      241 cgttttaagt gctatcattg ctcaaaaatg gaggtcgctg agacttctat cgtcaagaag
      301 aatcatcaaa ttccttgtat catcaaccaa aagattgatc agaagctaat tgaaaagact
      361 tctatgaccg acattgatca tcagttgtct atttcaactt caactgtcat tcgcaagatc
      421 aatgattttc actttgagca tgatttttcg cgtcttcctg agattatgtc ctaggacgtt
      481 gaaacagtct ggggagtgac tgtttcaatc gggagataga gatgagcttt attgctcagg
      541 actttgataa gctcaatatc ataactgttc ttgagagcag aacacaagcc atcatccgaa
      601 atcccatgaa tacaaggcta tcaagcgata ctgaaagctc attcaacaag atagtcagaa
      661 actgagtgat aaacgatttt atcgccctac ttttcgtatg cacttgacta ataaagaaat
      721 tctagataaa cttttgagct attccgaaga cttgaaacac cactataatc tctatcagct
      781 cttgcttttc caccctgttt aaaaccttcc tcaaagataa agagaaaatc gtcaacgccc
      841 ttcaattacc ttattccaac gccaaactgg aagccaccaa taatctcatc aaacttatca
      901 agcacaatgc ctttggtttt aggaactttg aaaacttcaa aaaagaaagg acgaaatttg
      961 tcctttctag atcttcgctt tcttcaaccc actacagttg acaaagaacc gaaaaatgtc
     1021 tcgcctctaa tatagtcaat tgaaacaaga gcaggacaaa agagcctcgt aaaaggtatg
     1081 gcaacgtggt aatacctttt tgaggttctt tttgatatga gcccatgttt tctcaatagg
     1141 attgtactca ggtgagtagg gaagaagagg taaaagttta tgcccaaact cttcacataa
     1201 aagttctagc ttacccattc tatggaatct tgcattgtcc ataatatagt agattgaaac
     1261 tagaatagta cacctctact tctaaaacat tgttagaatt cgattttact gtcctgatcg
     1321 atttgtccta ttcttatttc attttgctat aacacgaaat agattattat tacataacaa
     1381 aaaagaggtc taaacctctt aactaaatta ctccgccagt aggactcgaa cctacgacat
     1441 catgattaac agtcatgcgc tactaccaac tgagctatgg cgga
//
LOCUS       DAVLGK010000105         1376 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLGK010000105 DAVLGK010000000
VERSION     DAVLGK010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1376
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.106"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(201..617)
                     /locus_tag="VXE01_002206"
     CDS             complement(201..617)
                     /locus_tag="VXE01_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0751033.1"
                     /translation="MITIKKQEFVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLAI
                     YVALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSTLMKEALEDYKDAYQVQ
                     LVTEQTERTLGFYCSMGFEILSTYDCIGMTWINREK"
     gene            complement(629..1324)
                     /locus_tag="VXE01_002207"
     CDS             complement(629..1324)
                     /locus_tag="VXE01_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0751034.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELTFIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMEELVSLLNQMLARKDRFYYAIIDRSTGKVLG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAF
                     NLPSRRAAERLGFIYEGTFRQAVVYKGRTRDTDWLSMTDKDWPKVKDRLETWLRPENF
                     DKNGQQYKSLREL"
BASE COUNT          408 a          334 c          227 g          407 t
ORIGIN      
        1 ctcaaattat accattttta aaaaaatttc tatcagcatc acctcaccct acaaaaaagc
       61 cacctgatta ggtgacttca ttaggagatt atgatgaaaa aagttttagg atttcattaa
      121 ataaagttag gaggtcttta tttaatgact atatgatact agaccagcct taaactttgc
      181 ttaagaacaa ccaagtttta ttatttttct ctgtttatcc aagtcattcc tatacaatca
      241 taggtggata agatttcaaa gcccatagaa caatagaagc ccaaggttct ttctgtctgt
      301 tctgttacca gctggacttg ataggcatct ttgtaatcct ctaaagcctc tttcattagg
      361 gtactaccaa tcccttgacg ttgatagatt ggtaaaacga ttaaatcctg aaccaatact
      421 gatgagaatc catctccaac caaacgaatc aagcccacca cagcatcgcc atcaagcgcc
      481 acataaatcg ctaatgaatg agataaggcc tgctccagca tctctggttg atgggtataa
      541 tttgtccaac cgacagcctg atagagatgc aaaacatcct ctagcttgac aaattcttgc
      601 tttttaatag taatcatctc aacacctctt aaagctctct caagctcttg tactgctgtc
      661 catttttatc aaaattttca ggacgcaacc atgtttccaa acgatctttg actttgggcc
      721 agtccttatc agtcatagac aaccaatccg tatccctcgt acgcccctta taaaccactg
      781 cctgacggaa ggttccttca taaataaagc ccaaacgttc tgcagctcgt cttgatggca
      841 gattaaaagc atcgcatttc cactcatagc gacgatagtt aagctcttca aagacatagc
      901 gagccagtag atactgggct tctgtcccta tccgtgtccc cctgagttct ggagaaaaag
      961 tgacagctcc cacttctatt actcggttat tctggtcaat gcgcatgaga gaaaaagttc
     1021 ccaaaacctt accagttgac ctgtctatga ttgcatagta aaaacggtcc ttacgagcca
     1081 acatctgatt taaaaggctg accagttcct ccatgtctgc tactggttcc tgaaagaggt
     1141 aggtccacat ctcctgagga gtatccgggc cataaacagc taacaaatcc tccgcatgtt
     1201 tttctaccga gagagcctct atccgagcat aacgtccttc taagaaatca ataaaagtca
     1261 gttcacctgg tgtataacct tccattgact caccaatcat ctgaccatat tcgtttactg
     1321 gtataacttt ctccttgttt cgcttttcaa actttatagt tgcccatagt atagcg
//
LOCUS       DAVLGK010000106         1322 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLGK010000106 DAVLGK010000000
VERSION     DAVLGK010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1322
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.107"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..151
                     /locus_tag="VXE01_002208"
     CDS             <1..151
                     /locus_tag="VXE01_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0751035.1"
                     /translation="LTSIIRQALKNTEYKDQISSTVLPDIKIKLPIDSRGTPDWNYME
                     RYRDR"
     gene            117..431
                     /locus_tag="VXE01_002209"
     CDS             117..431
                     /locus_tag="VXE01_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751036.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            1105..1290
                     /locus_tag="VXE01_002210"
     CDS             1105..1290
                     /locus_tag="VXE01_002210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751037.1"
                     /translation="MKKKGGMHVDNDWNGLAELFANLITKYAGVLDLDNLPDPTPAKN
                     QEMKNSFDMAKTQIETD"
BASE COUNT          541 a          162 c          257 g          362 t
ORIGIN      
        1 tttaacttca attattaggc aagctttaaa aaatactgaa tataaagatc aaatatctag
       61 cacagtattg ccagatatca aaattaaatt accgatagac agtagaggta ctccagattg
      121 gaattacatg gaaagatata gagatagata aagagagaga gggagagata gataaaaagt
      181 ccacccccat tttttatgga gaattcaaaa atgtaaggtt aagcaaagaa gaatataaaa
      241 atctaaaaga aaaattaaac tcacacacag atataatgat aaataaacta tccagataca
      301 tggaaagcag tggtaagacc tatcaaaacc actatgtgac aatcttaaaa tggtatgaag
      361 aagataaaga caaactaaga cagaaaggtt taaataaaaa aatgaattat gatgtaggag
      421 aatctttata gataaaaaga ggtggaaagg cactattaaa gactttaagt ctaaaaaggt
      481 atcaaagtat gccagagata aaaaaatata aatatgacac tttaaaggcg attagaaaat
      541 taaagaaatg ctagaagact tttagatgac agttaccaag agggtctaat tttcactgct
      601 acttatgcag tgggaattgg acctttttat ataagcaaat tctatttcaa aattggttac
      661 caagaaagac ttcttttcac tgttaagtat aagagggtaa tttatagaat tttgttacat
      721 caagataaat attttatgat ggtcaaattt taaaaagatt aataactctc gataaatttt
      781 gaaccttaac aattgaatag accaagacaa gacgttaatt atttttggag cgtaataacc
      841 tatccgtcaa gatctttcgg ctgaataatt cggcaaaaaa agttctgcta agcaaaaaga
      901 aagtgagcga taagtaagag tttgaatata gggagggata ccctatccgc tatgaagaaa
      961 atgaggataa tgatacttct ttagtgaaag ccggctcatc ttaacagggg cggtggtgag
     1021 attccaatgt tgctgatcct aagcacccgt taatgtcatg aaacttagtt agatgagaaa
     1081 gttatagatt gattatataa gagtttgaag aaaaaagggg ggatgcatgt ggataatgac
     1141 tggaatggac tggctgagtt gtttgcgaat ctaattacaa agtatgctgg tgttttagat
     1201 ttggataatc tgccagatcc aacgccagca aaaaatcaag agatgaaaaa tagttttgac
     1261 atggcaaaaa cacaaattga gacggactaa taaaagtgtt ataatatact tgaaatgata
     1321 gt
//
LOCUS       DAVLGK010000107         1311 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLGK010000107 DAVLGK010000000
VERSION     DAVLGK010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1311
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.108"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            108..>1311
                     /locus_tag="VXE01_002211"
     CDS             join(108..447,447..>1311)
                     /locus_tag="VXE01_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV0751038.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYAYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKEIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKGL"
BASE COUNT          473 a          221 c          288 g          329 t
ORIGIN      
        1 aattgagtta tgaagataaa gttcagatct atgaactaag aaagcaagga caaagcttca
       61 aacagctttc aaaaagattt ggtgtggatg tttctggtct aaagtacatg gtgaaattaa
      121 ttgaccgtta tggcatagaa atcgttaaaa aagggaagaa tcgtcactat tcttctaaat
      181 tgaaacaaga aatgatggat aaagccttac tggaaggttg ttcacaaaga agtattagtc
      241 ttgattatgc cctcccaaac caaggaatgc tttcattttg gccggcacaa tacaagaaaa
      301 acgggtatac tattgttgag aaaacaagag ggagaccagc taaaatggga cgtaaacgga
      361 agaagacttg ggaagaaatg acagaactag aacgactcca ggaggagaat gaacgcttac
      421 ggactgaggt ggcctaccta aaaaagttaa aagagttaga ggaaagggac gaagccctag
      481 agcgagaaag gcagagacag ttagagaaat ggtttcagga ggatttcgac tagattttct
      541 tcttgaaaca gcacgtttag ctcgctcgac ttactattat cagttgaaac aactggatgg
      601 ggttgataaa gataaagaga ttaaaaccga aattcagggc attgataatg aacataaagg
      661 caactatgcc tatcgtcgaa tccatttaga actaaggaat cgtggttttg tggtcaatca
      721 taagaaagtt caacggttga tgagaattct tggtttaacg gctcgaattc gccgtaaacg
      781 gaagtattct tcctaccaag gagagattgg caagaaagca gagaatctca ttcaacgcca
      841 gttcgaagca tcgaggccaa tggaaaagtg ctatacagat gtgacagagt ttgccattcc
      901 aaatagcaca cagaaactct atttatcacc agttttagat ggttttaaca gtgaaatcat
      961 tgcttatcat ctttctactt cgccaaactt agaacaagtg aagagtatgt tagaacaggc
     1021 ctttacagag aaatactatg agaatacgat tctccatagt gaccaaggct ggcaatacca
     1081 acacgattct tatcatcggt tcctagagag taaggaaatt caagcatcca tgtcacgcaa
     1141 gggcaacagc ccagacaacg gcatgatgga atctttcttt ggcattttaa aatccgaaat
     1201 gttttatggc tatgagaaga actttagatc tttagaaaac cttgaacaag ctattgtgga
     1261 ctacattgat tactacaaca acaaacgaat taaggtaaaa ctaaaaggac t
//
LOCUS       DAVLGK010000108         1288 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLGK010000108 DAVLGK010000000
VERSION     DAVLGK010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.109"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            9..>1288
                     /locus_tag="VXE01_002212"
     CDS             9..>1288
                     /locus_tag="VXE01_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEV0751039.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPL"
BASE COUNT          485 a          153 c          229 g          421 t
ORIGIN      
        1 gttaaaatat ggaagaaaat tataatttat ctataactca aataaagaat tctattaaag
       61 aaaattcctt agttttgttt gttggtgcag gaatatcagc taattctaat ctaccaactt
      121 ggggagaatt gattcaatca ttaaaaaaag aattgaacat accagaagaa agaacagata
      181 gtccactgag aattgctcag tattattatg atacttttgg gaaaaatcag tacacaaaga
      241 agatagaaga aattttcttt aagaagggat tgagtaaacc aaatgagtta cataaattaa
      301 tagaaaaaat tgcaccaaaa catattatta cgacaaacta tgattcactt ctggagagtc
      361 aatttgaaag tggcttgtta aagtacaatg tagtcgctga ggataaagac atcccttata
      421 cgagttcgga aagatacttg attaaaatgc atggtgactt cagtaagaaa aatattgttt
      481 tgaaagaaga tgattattta gactatcatt tgaacttccc aatgatttct actttaatcc
      541 agtcattgat aatgaatcat actctattgt ttgtggggta ttctctaagt gattcgactt
      601 ttaattcaat ttttagaatg attcaaaata catttaaatt ggatgctaaa aatgcttatt
      661 tttatactcc cgaggaaccg tctatgatca ttcgagagta ttataagaag caaggaattt
      721 tcattatctc taatgaagag aatctaggtc aggagacatc agaaaaacag aacaaattgt
      781 attgcaggac aaaagatttt ttagaggttc tatcagaaaa ccgaagtcaa gatgtaaata
      841 atgctgatga tttatggaat caactggctt ttttagatag acttagtttt attgatgcga
      901 aagatttttc tagatattct gatttaaaga aaagggcttt aaactgggat gatgagtatt
      961 gctggtttgg aaatgatcaa ttaagatttg aaattgatgg tcatgaagaa ttacgaatta
     1021 tggtatctaa aaaatcttta ttaaatcgct ttctagatat ggagattggt gagcctaggg
     1081 atttaaaggg gaatcgattc ttaagtaagg cttttaagtt gtatgaagaa aaacaatatt
     1141 ctttagcaaa agcaaaattt agagaactag ctaatatagc atttcgtcag aaagactatt
     1201 ttaatttctt agtttgtgaa tttaattttc agcaaattca aataattgat agatacgaaa
     1261 aaacacctag ttatgcagag ccacttta
//
LOCUS       DAVLGK010000109         1213 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLGK010000109 DAVLGK010000000
VERSION     DAVLGK010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1213
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.110"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            26..>1213
                     /locus_tag="VXE01_002213"
     CDS             26..>1213
                     /locus_tag="VXE01_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0751040.1"
                     /translation="MGQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIKQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGL
                     IEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FENF"
BASE COUNT          398 a          264 c          190 g          361 t
ORIGIN      
        1 caaacaactc attagaaaga ttcatatggg acaattacat tttatcacaa aactactcga
       61 tatcaaagac acaaatatcc aaattataga tgtcgtcaat agggattcac acaaagaaat
      121 catcgccaaa ctggactacg acgccccatc ttgccctgat tgtggaagtc taatgaagaa
      181 atatgacttt caaaaaccgt ctaagatccc ttacctcgaa acaactggta tgccttctag
      241 aattctcctt agaaaacgcc gtttcaagtg ctatcactgt tcaaaaatga tggttgctga
      301 gactcccctg gtaaagaaaa atcaccaaat ccctcgtatc atcaaccaaa aaattgctca
      361 aaagttaatt gaaaaaattt ctatgactga tattgcccat cagctggcca tttcaacttc
      421 aactgtcatt cgcaagctca atgactttca ctttgagcat gatttttctc ggcttccaaa
      481 gattatgtct tgggatgagt atgccttcac taagggaaag atgagtttca ttgcgcaaga
      541 ttttgataat cttaatatta tcactgttct tgaaggcaga acacaagctg tcatccgaaa
      601 tcactttctt cgctacgata gagccgttcg ttgtcaagtg aaaatcatta cgatggatat
      661 gtttagtcct tactatgact tggctaaaca gctttttccg tgtgctaaaa tcgttctaga
      721 tcgtttccat attatccaac atctcagccg tgccatgagt cgttttcgtg ttcaaattat
      781 gaatcagttt gaacgaaaat ctcatgaata caaggctatc aagcgttact ggaaactcat
      841 caaacaggat agtcgtaaat tgagcgataa acgtttttat cgccctactt ttcgcatgca
      901 cttaacaaat aaagaaattc ttgacaagat tttaagctat tcagaagact tgaaacacca
      961 ctatcagatc tatcaactct tactttttca ctttcagaac aaagaccctg agaaattttt
     1021 cggactcatt gaggacaatc tgaagcaggt tcatcctatt tttcagactg tctttaaaac
     1081 ctttctaaag aacaaagaga aaatcgtcaa cgcccttcaa ctacactatt ctaatgccaa
     1141 actggaagcg accaataatc tcatcaaact tatcaagcgc aatgcctttg gttttcggaa
     1201 ctttgaaaac ttc
//
LOCUS       DAVLGK010000110         1150 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLGK010000110 DAVLGK010000000
VERSION     DAVLGK010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1150
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.111"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>1150
                     /locus_tag="VXE01_002214"
     CDS             <1..>1150
                     /locus_tag="VXE01_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0751041.1"
                     /translation="KSELTQTAEELSSKIASVQVGGINLLRNTASLLIGDRSKGCWMS
                     ASGGNGRAISVEVLDSPKKMIKNMIRVIENTNGGNKDLTQLVRLRIGEKYTISCYARI
                     ASDSPNANVNLLFRSWANNTDLNRKFQKSISHKNWQKYSFTFTADAIENSIQFGQSGA
                     GIIEICAPKIESGTLATDYSEAPEDIEGQISTVESTFKQRANSLDAGVRSLTEGLRTK
                     VDISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKADK
                     TLVVSEAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPENHVTGQKECYRLENNSTL
                     TFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFKHYLFRKNS"
BASE COUNT          393 a          200 c          260 g          297 t
ORIGIN      
        1 caagtcagaa ctcacgcaga cagctgagga gctctctagt aagatagcga gtgtgcaggt
       61 cggaggaatc aacctcttgc gtaatactgc gagtttgttg attggcgatc gttcaaaagg
      121 atgttggatg agtgcaagcg gaggaaatgg gcgagcgatt agcgtagaag ttttggattc
      181 tcccaaaaaa atgataaaaa acatgattcg tgttattgaa aatacgaatg gtggaaataa
      241 agatttaact caacttgtta gattgcgaat tggtgaaaag tacacgattt cttgttatgc
      301 aaggattgct agcgatagcc caaatgcaaa cgtgaacttg ctatttcgtt cgtgggcaaa
      361 taataccgat ttaaatcgca aatttcagaa atccatctct cataaaaatt ggcaaaaata
      421 ttcatttaca tttactgctg atgcaattga aaattcaatt caatttggac aatctggcgc
      481 aggaattatc gaaatatgcg ctccgaaaat cgaatcagga acgttagcga ctgattacag
      541 cgaagctcct gaagatatag aaggtcagat ttcaacagtt gaatcgacct tcaaacaacg
      601 agccaactca ctcgacgctg gtgtaagaag cttgactgaa gggcttagaa ccaaagtgga
      661 tatcagttca ctcaatgtga ctgctgaaaa tatccggcaa tctgtgaaga gccttgagac
      721 agacacgcag aacaagctaa atcagaagtt gagtcaggct gaatttgagg tgcgagccgg
      781 ctctatccgt caggaaatcc tgaacgcaac caaggataaa gcagataaga ctttagttgt
      841 atctgaagct gggaaattgc gtgaagaatt ttcaaaaatg aaggtgggag gccggaatct
      901 atggataaaa tccaagacgg ttggagctgt aattgaaaaa ttacctgaaa accacgtcac
      961 aggtcaaaaa gaatgctata ggctagagaa caactctact ttaacgttca accttgaacc
     1021 agatttcagc tcaaggttgt accaaaaagt tacttttagc gcttggatca agtacgaaaa
     1081 tgtagtccaa ggtcgaaatt tttggaatgt atttaattgc ttcaaacatt atctttttag
     1141 aaaaaatagt
//
LOCUS       DAVLGK010000111         1120 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLGK010000111 DAVLGK010000000
VERSION     DAVLGK010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1120
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.112"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            184..387
                     /locus_tag="VXE01_002215"
     CDS             184..387
                     /locus_tag="VXE01_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HEV0751042.1"
                     /translation="MNTKMMEQFSVMDNEMLDRIEGGIFGVDDALFWAGLGYVAGSIV
                     DTAIDDFTNQCRKNPHQWFCVRV"
     gene            705..908
                     /locus_tag="VXE01_002216"
     CDS             705..908
                     /locus_tag="VXE01_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pncT"
                     /protein_id="HEV0751043.1"
                     /translation="MEKIDYITLNEVELETISGGDDCFIGDIGCIGWGLLKSIGGMIK
                     PAPYVPPVCIPKSSWNPAPPVPC"
BASE COUNT          390 a          147 c          217 g          366 t
ORIGIN      
        1 gtaaaaaagt gattagaaaa catctttttt aaaaatagag atgattttga aacaaaaaag
       61 ctaattcaag acgtttcgat gccaattcaa gatttggatg aaaaaaatta aaaaataatg
      121 atatactaaa cttgtcaaag ttgcaacaag acaaaaatta aaaataaaaa aggagtattt
      181 gtcatgaata caaaaatgat ggaacaattt tctgttatgg ataatgaaat gcttgatagg
      241 atagagggag gaatatttgg agttgacgat gctttgtttt gggcagggtt aggctatgtt
      301 gcaggtagca ttgttgatac agcaattgat gattttacga atcaatgccg gaaaaatcct
      361 catcagtggt tctgtgttcg tgtatagata tagtagtgtt gtattgtata agaatttata
      421 taacttaatg acctatgcag tgatagaaac tattcttttg caaacgagtc gcttattctg
      481 ttataagttt acgtgctcct agtcacagtt cttgtgcttg atagaaagaa tgacacctat
      541 aaagatgcga gatattggct atatcactca cttattcacc tccccgtgat ttgtagtagt
      601 gataggtttt ctcactatta ttataaacat tataaaataa agagtacaac actttttcat
      661 tctgtgttgt gccttgagta aaacgaaagg aatgaattat aacaatggaa aaaattgatt
      721 atattacttt gaatgaagta gaattagaga cgattagtgg tggagatgac tgttttattg
      781 gagatatcgg atgtatcggc tgggggcttt tgaagagtat cggagggatg ataaaacctg
      841 ctccatatgt tcctccagta tgcattccaa aaagttcgtg gaatcctgca cctccagttc
      901 catgttaaaa agttattgta aacttatata aaaaatgaat aatcgacttg ttcgctattt
      961 tgttgaatct tcgcaactat aatatacagg tgttgttcag gattatttta gcttattgca
     1021 agagtcgaaa actagaaact aatggctggt tggaacgtta aaaattcact ttctaaccag
     1081 ctaatactgc ttcaaataat ttctgaacaa gtctaataaa
//
LOCUS       DAVLGK010000112         1065 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLGK010000112 DAVLGK010000000
VERSION     DAVLGK010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1065
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.113"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>1065
                     /gene="phtD"
                     /locus_tag="VXE01_002217"
     CDS             <1..>1065
                     /gene="phtD"
                     /locus_tag="VXE01_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0751044.1"
                     /translation="LRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPID
                     EKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKT
                     DLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDI
                     LAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYV
                     TPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDLGNTEAKGAEAIYNRVK
                     AAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYSLEDLL
                     ATVKYYVEHPNERPHSDNGF"
BASE COUNT          345 a          222 c          230 g          268 t
ORIGIN      
        1 cccttcgtta tcgttcaaac cattgggtac cagattcaag accagaacaa ccaagtccac
       61 aatcgactcc ggaacctagt ccaagtctgc aacctgcacc aaatcctcaa ccagctccaa
      121 gcaatccaat tgatgagaaa ttggtcaaag aagctgttcg aaaagtaggc gatggttatg
      181 tctttgagga gaatggagtt tctcgttata tcccagccaa ggatctttca gcagaaacag
      241 cagcaggcat tgatagcaaa ctggccaagc aggaaagttt atcgcataag ctaggagcta
      301 agaaaactga cctcccatct agtgatagag aattttacaa taagacttat gacttactag
      361 caagaattca ccaagattta cttgataata aaggtcgaca agttgatttt gaggctttgg
      421 ataacctgtt ggaacgactc aaggatgtct caagtgataa agtcaagtta gtggatgata
      481 ttcttgcctt cttagctccg attcgtcatc cagaacgttt aggaaaacca aatgcgcaaa
      541 ttacctacac tgatgatgag attcaagtag ccaagttggc aggcaagtac acaacagaag
      601 acggttatat ctttgatcct cgtgatataa ccagtgatga gggggatgcc tatgtaactc
      661 cacatatgac ccatagccac tggattaaaa aagatagttt gtctgaagct gagagagcgg
      721 cagcccaggc ttatgctaaa gagaaaggtt tgacccctcc ttcgacagac catcaggatt
      781 taggaaatac tgaggcaaaa ggagcagaag ctatctacaa ccgcgtgaaa gcagctaaga
      841 aggtgccact tgatcgtatg ccttacaatc ttcaatatac tgtagaagtc aaaaacggta
      901 gtttaatcat acctcattat gaccattacc ataacatcaa atttgagtgg tttgacgaag
      961 gcctttatga ggcacctaag gggtatagtc ttgaggatct tttggcgact gtcaagtact
     1021 atgtcgaaca tccaaacgaa cgtccgcatt cagataatgg ttttg
//
LOCUS       DAVLGK010000113         1032 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLGK010000113 DAVLGK010000000
VERSION     DAVLGK010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.114"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(242..>1032)
                     /locus_tag="VXE01_002218"
     CDS             complement(242..>1032)
                     /locus_tag="VXE01_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000925815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEV0751045.1"
                     /translation="QIKKNFIYLIPIAIFFVYAIISGGRLPLIRLVVGALLILYIYSV
                     YGSPKSQLTKSFKMITRSLFAFLILIVLFFLLKFVLGRSSQEDFISYITRYMGGSIQL
                     FDLFVIDPIRRNKELGAETFSGIYEMLAKLGFDNNIIKGLEWRVSPNYYSLGNVYTAI
                     RRYYSDFGVIGIVICQSFTAWLYTLGYEKVRHYSLVTNVQRFRLILLAASFYPIFLNS
                     IEDVFYISMVTIGYGIQIVIFYLVFWVLLKVQVDFNKGKLTINR"
BASE COUNT          403 a          190 c          123 g          316 t
ORIGIN      
        1 ctcagttact cccataattt ttggtaaaat tagtacaact ataaccgatg tgacaattgt
       61 aatcagatta gacaaaaaga catgaaataa atttgttata agaaacttca atttcatagc
      121 tatactcccc acctaaaaat tgtttcagaa gatttgtact tcccattcaa ggctctcttc
      181 ctccaattaa aatacctacc aaatatatcc ctttatatga ttcaatacat tagcgctaaa
      241 ttcatctatt tatcgttaat ttacctttgt taaagtcaac ctgaactttc agaagaaccc
      301 aaaagaccag ataaaagata acaatttgta ttccatatcc aatggtaacc attgaaatat
      361 aaaacacatc ctcgatacta tttaaaaata ttggataaaa tgaagctgct aataggatca
      421 acctaaatct ttgaacattt gtaactaaag aataatgtct aactttttca taacctaaag
      481 tatataacca cgctgtaaaa ctctgacaaa ttacaatacc aattacacca aagtctgaat
      541 aataacgtct aattgcagta tacacatttc ctaaagaata ataattagga gacactctcc
      601 attctaagcc ttttataata ttattgtcaa atcctaattt tgcaagcatc tcataaattc
      661 ccgaaaaagt ttctgcacct agttctttgt tacgtcgtat cggatctata acaaataaat
      721 caaatagttg aattgaacct cccatataac gagtgatgta actgataaaa tcttcctgag
      781 aggagcgccc taatacaaat tttaaaagaa agaataaaac tatcaaaata agaaatgcaa
      841 acagagagcg agtaatcatt ttaaaacttt tggtaagttg agatttagga ctcccgtaca
      901 cagagtatat atacaatatc aacagagctc caacaactaa ccttataagg ggcaatctac
      961 caccactaat gattgcatag acaaagaata tagctattgg aatcaaataa atgaaatttt
     1021 tctttatttg tt
//
LOCUS       DAVLGK010000114          886 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLGK010000114 DAVLGK010000000
VERSION     DAVLGK010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..886
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.115"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..397)
                     /locus_tag="VXE01_002219"
     CDS             complement(<1..397)
                     /locus_tag="VXE01_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0751046.1"
                     /translation="MVTIKDIARVSGVSHGTVSNVLNKKGNVSAAKIKLVEETAKKLG
                     YNMNSQAQFLRKGASSKCFFLLFNNARKKYAEYFAEIDQLSLDVEYVYLHKFSEIKNK
                     ISAILSENPQFIVCLGFSPKRFVDIEDNIP"
     gene            complement(407..>886)
                     /locus_tag="VXE01_002220"
     CDS             complement(407..>886)
                     /locus_tag="VXE01_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEV0751047.1"
                     /translation="NLWIDLDNGKISLEFLENQLIDEMGHQYQDQIHELVWNWFNYVD
                     LYDEVYELIKQLKKKNFQIYVLSNTSSIFHILLDSVLSKVSSVLDGYVISCEVKMMKP
                     QKEIYLSLVNKYQLDIKDCIFLDDLEENVEAARTLGIKAFQIKERKEISNILKDLLN"
BASE COUNT          312 a          147 c           94 g          333 t
ORIGIN      
        1 tcggaatatt atcttcaata tcaacgaatc tttttggaga aaaacctaag caaactataa
       61 attgaggatt ttcacttaaa attgcagata tcttattttt aatctctgag aatttatgta
      121 agtaaacata ttctacatct aaagataact gatcaatttc tgcaaaatac tcagcatact
      181 ttttgcgtgc attattaaat aacaagaaaa aacatttact agaagcgcct tttcgaagaa
      241 actgagcttg agaattcata ttataaccca attttttcgc agtctcttct actaacttta
      301 ttttagctgc tgagacatta ccttttttat ttaaaacgtt tgaaactgtc ccatgtgaga
      361 ctccagacac tcttgcaata tcttttattg taaccataat taacctctag tttaagagat
      421 cttttagtat atttgagatc tctttacgct ctttaatttg aaatgcttta atacctagag
      481 ttcttgcagc ttctacattt tcttctaaat catctaaaaa tatacaatct tttatatcta
      541 attgatattt attaactaat gacaagtaaa tttctttttg tggtttcatc attttaactt
      601 cacaagaaat tacgtaacca tctaaaacag atgatacttt agatagaaca gaatctaata
      661 aaatatgaaa aattgaggag gtatttgata aaacataaat ttgaaaattc tttttcttta
      721 gctgttttat taattcataa acttcatcat ataaatcaac atagttaaac caattccata
      781 ctaactcatg aatttgatcc tgatattgat gtcccatttc atcgattaat tgattctcta
      841 agaactctaa actaatttta ccattatcca aatcaatcca caagtt
//
LOCUS       DAVLGK010000115          878 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLGK010000115 DAVLGK010000000
VERSION     DAVLGK010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..878
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.116"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..476)
                     /locus_tag="VXE01_002221"
     CDS             complement(<1..476)
                     /locus_tag="VXE01_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0751048.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSSL"
     gene            complement(478..>878)
                     /locus_tag="VXE01_002222"
     CDS             complement(478..>878)
                     /locus_tag="VXE01_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV0751049.1"
                     /translation="LLIAYTIQKLPFSYRMIRAVFFSIDNDMEEAARSMGASSFYTMV
                     RVIIPYILPVVLSVVVLNFNSLLSDYDLSVFLYHPLFQPLGIVIKQSTDETATLNAQA
                     MMFVYSVILMIMSSAALYLSSLFQGKRGKR"
BASE COUNT          318 a          173 c          135 g          252 t
ORIGIN      
        1 tctaaagaac taaaaaccaa gtagtaatca gcaattttag ttttcgagtt taaataatct
       61 ttaagaggag taaatagagt taaaactgct atgagtacaa ctccggctaa aatagcacct
      121 tcataaaaac caatgcctat agctaaacca atagttgctg aagaccataa tccagctgct
      181 gttgttaaac ctttaacttt ttgattagtt accatgattg ttcctgcccc taggaaaccc
      241 aagccactaa ttacttgggc tcccattcga ctaggatcac cgctaccata acgactagtg
      301 atgaactgat ttgtcatcat tacaacacaa gttcccaaac aaactagtaa gtaggttcta
      361 atccctgctg cttggttttt gactcctcgc tcatagccaa caatgccacc gaaaagaatc
      421 gctaaaaagc acctaagaag tatttcccaa atactcagtt cgtatgaaag attcatatta
      481 tctcttacct cgtttacctt ggaataggct tgataaataa agagctgcac tagacataat
      541 cattaaaatt acagaataaa caaacatcat tgcctgtgca tttaaagttg ctgtttcatc
      601 agtagactgt ttaataacga ttcccaatgg ttggaaaagt ggatggtaca agaatacaga
      661 taagtcatag tcagataata aagaattaaa gtttaacaca actactgata atacgactgg
      721 taaaatatac ggtataataa ctcgcaccat agtgtagaaa ctagatgcac ccatactacg
      781 tgctgcttct tccatatcat tatctatact gaaaaataca gcccgaatca ttctataaga
      841 aaatggtaat ttttgaatag tatatgcaat aagtaaaa
//
LOCUS       DAVLGK010000116          750 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLGK010000116 DAVLGK010000000
VERSION     DAVLGK010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..750
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.117"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            complement(<1..>750)
                     /locus_tag="VXE01_002223"
     CDS             complement(<1..>750)
                     /locus_tag="VXE01_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751050.1"
                     /translation="LFVYILQMTNRLKDSSIILISDRVIYIFLLFLFIIFKWHEYKVM
                     IWADVLGRTFSLLLSFWTCKDIVFQSLSEFILDLRESFDNIRVGINLMLSNIASSMII
                     GIVRMGIQWNWNIETFGKVSLMLSISNLLMTFINAIGLVVFPLLKRTKTENLSKIYSN
                     LRNVLMLIMFAILLFYYPLKIILDLWLPAYRDALIFMALIFPMSIYEGKMALVINTYL
                     KALRMERDILKINTLIMLFSMLVTLITTLLL"
BASE COUNT          304 a          132 c           94 g          220 t
ORIGIN      
        1 ttaataatag agtagttatt agggtaacta acatactgaa caacataatc aaagtattta
       61 ttttgagaat atctctttcc atccttagcg cctttaaata tgtattaatc accaaggcca
      121 tcttcccttc ataaattgac ataggaaaaa taagagccat aaaaatcaac gcatcccgat
      181 aagctggcaa ccaaagatct agaataattt ttaaaggata ataaaagagc aatattgcaa
      241 acatgatcag catcaaaaca tttcttaagt tggaataaat tttagataaa ttttccgttt
      301 ttgtccgttt taacaaagga aagacaacta aaccaatcgc attaataaaa gtcattaata
      361 aattagagat gcttagcatc agtgatactt tcccgaatgt ttcgatattc caattccatt
      421 gaattcccat tcgaacaata ccaataatca tactacttgc aatattggat aacattaagt
      481 tgattccaac acggatattg tcaaaagact ctctcagatc caatatgaac tcggataagg
      541 attgaaaaac aatatcttta caagtccaaa aagaaagtag gagagaaaat gtccttccta
      601 aaacatccgc ccaaatcatt accttgtatt catgccattt aaatataata aacagaaata
      661 aaagaaaaat atatataacg cgatcactta tcagaattat agagctatcc tttaatcgat
      721 ttgtcatctg caaaatataa acaaataaca
//
LOCUS       DAVLGK010000117          651 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLGK010000117 DAVLGK010000000
VERSION     DAVLGK010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.118"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..608
                     /locus_tag="VXE01_002224"
     CDS             <1..608
                     /locus_tag="VXE01_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0751051.1"
                     /translation="EGGEYQIKNLSYKFTDDECLSLKDISFKLGKIYGIIGSNGRGKS
                     TLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVMQDVNHQLFTDEVFNELRLGVK
                     NFDEEKAKIILKDLCLDEFIERHPMSLSGGQKQRLAIASVMCKNSPFVFFDEPSSGMD
                     YSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADEIFEL"
BASE COUNT          252 a           74 c          124 g          201 t
ORIGIN      
        1 aagaaggtgg agagtatcag ataaaaaatc ttagctacaa atttactgat gatgagtgtt
       61 taagcttaaa agatatttca ttcaagcttg ggaaaattta tggcataata ggatccaacg
      121 gacgaggaaa atcaacgctt ttaagatgtt taataggtct tgagaaaaaa tcaaaagaag
      181 aaatttattt taagggagag aagctatcta aaaaagaaag actcaaaaac tcttcacttg
      241 ttatgcaaga tgtaaatcat caattattca cagatgaagt attcaacgag cttagattag
      301 gagtaaagaa ttttgatgaa gaaaaggcga aaatcatttt aaaagattta tgcctggacg
      361 aatttattga aaggcatccg atgagtttat caggagggca aaagcaaagg cttgcaatag
      421 catctgttat gtgcaagaat tctccatttg tcttttttga cgaaccttca agtggtatgg
      481 attattccaa tatgataaaa atatctgaac tgattaataa gtataaaacc atggataaaa
      541 taatttttat tgtttcccat gatatagaat ttttaaatga agtggcagat gaaatttttg
      601 aattgtaaaa tagagtctgt taaacatgtc tatagaactg gtaaattgtc t
//
LOCUS       DAVLGK010000118          501 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLGK010000118 DAVLGK010000000
VERSION     DAVLGK010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.119"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>501
                     /locus_tag="VXE01_002225"
     CDS             <1..>501
                     /locus_tag="VXE01_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0751052.1"
                     /translation="ILSNEDLGATNARNIDIKNSRGKYISFLDDDDEYMPDRILKLMA
                     CFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIAGTSFWLCKKEV
                     LELINGFEKIDSHQDGVVLLKLLAQGYQIDIVLEFLVNYYAHSKENGITGVTQKTINA
                     DEEYYN"
BASE COUNT          187 a           54 c          100 g          160 t
ORIGIN      
        1 taattttaag taatgaagat ttaggtgcaa ctaatgccag aaacatagat atcaaaaatt
       61 ctagaggtaa gtatatatca tttttagacg atgatgatga atatatgcca gatcgaattt
      121 taaagttgat ggcttgtttt aaaaagagta gaatgaagaa tttagcttta gtttatagtt
      181 atggaataat aatttatcca aatggtacac gagaagagga gaagaccgat tttgttggaa
      241 atcccttgtt tgttcaaatg gttcacaata tagcaggtac gtcattttgg ttgtgtaaaa
      301 aagaggtgct agaattaatt aatggttttg agaaaataga ttcacatcag gacggtgttg
      361 ttttattaaa actacttgct caaggatacc aaattgatat agtgctagaa ttcttggtga
      421 attactacgc tcacagtaaa gaaaacggta tcactggagt gacacaaaaa acaattaatg
      481 cagatgaaga atattataat t
//
LOCUS       DAVLGK010000119          476 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLGK010000119 DAVLGK010000000
VERSION     DAVLGK010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.120"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            145..>476
                     /locus_tag="VXE01_002226"
     CDS             145..>476
                     /locus_tag="VXE01_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0751053.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSR"
BASE COUNT          141 a          101 c           83 g          151 t
ORIGIN      
        1 ctaaaaacca tccagaatcc ttgccttagc ttagatcctg gatggtttct tttttcaccc
       61 aatgggtgtt ttttactaga caaaaaagag tttccccttt atggtataag tgtagaaaaa
      121 aacacaaaaa gaaaggaaac tcacatgaac agtttaccaa atcatcactt ccaaaacaag
      181 tctttttacc aactatcttt cgatggaggt catttaaccc agtatggtgg tcttatcttt
      241 tttcaggaac ttttttccca gttgaaacta aaagagcgga tttctaagta tttagtaacg
      301 aatgaccaac gccgctactg tcgttattcg gattcagata tccttgtcca gttcctcttt
      361 caactgttaa caggctatgg aacggactat gcttgtaaag aattgtcagc tgatgcctac
      421 tttccaaaat tgttggaagg agggcagctt gcttcacagc caaccttatc ccgttt
//
LOCUS       DAVLGK010000120          424 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLGK010000120 DAVLGK010000000
VERSION     DAVLGK010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.121"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>424
                     /locus_tag="VXE01_002227"
     CDS             <1..>424
                     /locus_tag="VXE01_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751054.1"
                     /translation="ELVNRDFVGKATYQEDVKGINQRIEAVKTSANKDIASQIASYRQ
                     SVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNRINSNKQGTDN
                     QISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFA"
BASE COUNT          152 a           71 c           91 g          110 t
ORIGIN      
        1 gtgagctggt caatcgtgat ttcgttggta aggctactta tcaagaagat gttaagggta
       61 tcaatcagag gattgaagct gttaaaacta gtgcgaataa agacatcgct agtcaaatcg
      121 ctagctatcg tcaatctgta gatggtaagt tcacggatat ttcaagtcag ataactactt
      181 ataagcaaga tgtgggcggt caaatcagtg gtctatcaaa tagacttaca agcagtgagc
      241 aaggaaccac tactcagatt tcaaatcttt caaatcggat aaacagtaat aaacaaggca
      301 cagataatca gatttcaaat ttaaagactc aggtcgctac aaacaaggat aatgctgaac
      361 gacaaatggg tagaatatct gatcaggttt ctgcaaacaa agcgaatgct gatagtcaat
      421 ttgc
//
LOCUS       DAVLGK010000121          412 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLGK010000121 DAVLGK010000000
VERSION     DAVLGK010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.122"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>412
                     /locus_tag="VXE01_002228"
     CDS             <1..>412
                     /locus_tag="VXE01_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0751055.1"
                     /translation="LNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYNAHYRA
                     HGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFRMDSGFATPK
                     LYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQD"
BASE COUNT          113 a           97 c           74 g          128 t
ORIGIN      
        1 ctcaaccttg aattggtcga attcttttta cagtttcacc agctaaacca actcattgta
       61 gatatcgatt ctacccattt cacaacttat ggcaagcaag aaggtgttgc ttataacgcc
      121 cactatcgtg ctcatggcta tcatcctctt tatgctttcg aggggaagac aggttattgt
      181 ttcaatgccc agcttcgtcc tggtaatcgt tattgttctg aagaggcaga cagctttatc
      241 acacctgttt tagaacggtt taatcaactt ctctttcgaa tggatagtgg ctttgcgacc
      301 ccaaaattat acgatttaat tgaaaaaaca gggcaatact acctcataaa actcaagaaa
      361 aatactgttc tgagccgtct tggagacctt tccctccctt gcccacagga tg
//
LOCUS       DAVLGK010000122          404 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVLGK010000122 DAVLGK010000000
VERSION     DAVLGK010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.123"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
BASE COUNT          130 a           60 c           84 g          130 t
ORIGIN      
        1 cactgtttga gttatctgcg gtaatctttc tagcttgtct ttgatttttg ttgttattta
       61 taaggtaaaa gaagctggac aaaaagtctt caaaatcgga aaaaggcagc ctatcgggtg
      121 ttcaaaaatc ttgataggat gtcctttatt atggaaagcc ttattggatt ttctcctcag
      181 attgagtttt tgatcagctt tatgagatag gttttgctag agatgtagcc catcatgtta
      241 tttttatgga cggtgggaaa attgttgaaa aaaataatgc ccatcaattc tttagtcgtc
      301 caagagaaga acgaaccaag caattttgga acgaattctt tcgaatgcga tctatatagt
      361 aaaatgaaac aagaacagga caaatcgatc aggacagtca aagc
//
LOCUS       DAVLGK010000123          404 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVLGK010000123 DAVLGK010000000
VERSION     DAVLGK010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.124"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..>404
                     /locus_tag="VXE01_002229"
     CDS             <1..>404
                     /locus_tag="VXE01_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751056.1"
                     /translation="VGKYSVSGPNLIKNSDFKNATNEWGSTQNLGRLVKHSFYHNGQK
                     DLMRLSNATKNENFLYSHRFNLERNTDYVLNFRGFNNSALASYDVYILGRRAGESDGF
                     TIVKKVVSSKKLSTSRCEDVSVTFNSGEMDNA"
BASE COUNT          139 a           62 c           86 g          117 t
ORIGIN      
        1 gttgggaaat atagtgtaag cggccctaac ctcattaaga atagtgattt taaaaatgct
       61 acgaatgaat ggggctcaac tcaaaattta ggaagattgg ttaagcatag cttttatcac
      121 aacgggcaga aagaccttat gcgtttaagt aatgcaacta aaaacgaaaa ctttttgtat
      181 agtcaccgtt ttaatcttga acgaaatact gactatgtac tgaattttag aggatttaac
      241 aacagtgctc tcgcaagcta tgatgtttat attttgggac gaagagcagg cgagagcgat
      301 ggattcacaa tcgttaagaa agttgttagc agcaagaaac tatctacctc tagatgcgaa
      361 gatgtctcag taacttttaa ttccggagaa atggataatg ctta
//
LOCUS       DAVLGK010000124          387 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVLGK010000124 DAVLGK010000000
VERSION     DAVLGK010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.denovo.125"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            72..302
                     /gene="blpU"
                     /locus_tag="VXE01_002230"
     CDS             72..302
                     /gene="blpU"
                     /locus_tag="VXE01_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0751057.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGVARGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
BASE COUNT          126 a           41 c          101 g          119 t
ORIGIN      
        1 agatactgtt atactaaact tgtcaagttt gtaacaagac aaatattaaa aataaaaaag
       61 aggtattcgt tatgaataca aaaaagatgt cacaatttga aattatggat actgagatgc
      121 ttgcttgcgt tgaaggtggc ggatgcaatt ggggagattt tgccaaagca ggtgttggag
      181 gaggagtagc acgaggtctt cagctaggaa ttaaaacaag aacatggcaa ggtgcagcaa
      241 ctggtgctgc gggaggagct atacttggag gtgtggccta tgcagcgaca tgttggtggt
      301 aattatggat tttaaaagtt ttattattgg tttagtagtt ggtatatttg gtccttatat
      361 ggatgattta attagaaaaa aattttt
//
LOCUS       DAVLGK010000125        14885 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034729
            SAMN33606576-rid17947933.guided.047, whole genome shotgun sequence.
ACCESSION   DAVLGK010000125 DAVLGK010000000
VERSION     DAVLGK010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606576
            Sequence Read Archive: SRR23725983
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721860.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721860.1
            Genome Coverage       :: 171x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:31:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,246
            CDSs (total)                      :: 2,198
            Genes (coding)                    :: 2,061
            CDSs (with protein)               :: 2,061
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 64 of 137
            Pseudo Genes (incomplete)         :: 72 of 137
            Pseudo Genes (internal stop)      :: 38 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14885
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606576-rid17947933.guided.047"
                     /strain="AUSMDU00034729"
                     /serotype="06C"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST4237"
     gene            <1..268
                     /locus_tag="VXE01_002231"
     CDS             <1..268
                     /locus_tag="VXE01_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751058.1"
                     /translation="EIDKKSTPIFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSR
                     YMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGESL"
     gene            942..1127
                     /locus_tag="VXE01_002232"
     CDS             942..1127
                     /locus_tag="VXE01_002232"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751059.1"
                     /translation="MKKKGGMHVDNDWNGLAELFANLITKYAGVLDLDNLPDPTPAKN
                     QEMKNSFDMAKTQIETD"
     gene            1219..2898
                     /locus_tag="VXE01_002233"
     CDS             1219..2898
                     /locus_tag="VXE01_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0751060.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEDRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            3166..3732
                     /locus_tag="VXE01_002234"
     CDS             3166..3732
                     /locus_tag="VXE01_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751061.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4053..4241
                     /locus_tag="VXE01_002235"
     CDS             4053..4241
                     /locus_tag="VXE01_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0751062.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4303..5061
                     /locus_tag="VXE01_002236"
     CDS             4303..5061
                     /locus_tag="VXE01_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0751063.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5119..5973
                     /locus_tag="VXE01_002237"
     CDS             5119..5973
                     /locus_tag="VXE01_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0751064.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            6085..6969
                     /locus_tag="VXE01_002238"
     CDS             6085..6969
                     /locus_tag="VXE01_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0751065.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7132..8871
                     /locus_tag="VXE01_002239"
     CDS             7132..8871
                     /locus_tag="VXE01_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV0751066.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKIPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            9146..9448
                     /locus_tag="VXE01_002240"
     CDS             9146..9448
                     /locus_tag="VXE01_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0751067.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            9504..9931
                     /locus_tag="VXE01_002241"
                     /pseudo
     CDS             9504..9931
                     /locus_tag="VXE01_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            10010..10597
                     /locus_tag="VXE01_002242"
     CDS             10010..10597
                     /locus_tag="VXE01_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEV0751068.1"
                     /translation="MGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            10846..11135
                     /locus_tag="VXE01_002243"
                     /pseudo
     CDS             10846..11135
                     /locus_tag="VXE01_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821711.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            11240..11542
                     /locus_tag="VXE01_002244"
                     /pseudo
     CDS             11240..11542
                     /locus_tag="VXE01_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            11698..12927
                     /locus_tag="VXE01_002245"
     CDS             11698..12927
                     /locus_tag="VXE01_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0751069.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            12947..>14885
                     /locus_tag="VXE01_002246"
     CDS             12947..>14885
                     /locus_tag="VXE01_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0751070.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDKEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNL"
BASE COUNT         5132 a         2171 c         3104 g         4478 t
ORIGIN      
        1 agagatagat aaaaagtcca cccccatttt ttatggagaa ttcaaaaatg taaggttaag
       61 caaagaagaa tataaaaatc taaaagaaaa attaaactca cacacagata taatgataaa
      121 taaactatcc agatacatgg aaagcagtgg taagacctat caaaaccact atgtgacaat
      181 cttaaaatgg tatgaagaag ataaagacaa actaagacag aaaggtttaa ataaaaaaat
      241 gaattatgat gtaggagaat ctttatagat aaaaagaggt ggaaaggcac tattaaagac
      301 tttaagtcta aaaaggtatc aaagtatgcc agagataaaa aaatataaat atgacacttt
      361 aaaggcgatt agaaaattaa agaaatgcta gaagactttt agatgacagt taccaagagg
      421 gtctaatttt cactgctact tatgcagtgg gaattggacc tttttatata agcaaattct
      481 atttcaaaat tggttaccaa gaaagacttc ttttcactgt taagtataag agggtaattt
      541 atagaatttt gttacatcaa gataaatatt ttatgatggt caaattttaa aaagattaat
      601 aactctcgat aaattttgaa ccttaacaat tgaatagacc aagacaagac gttaattatt
      661 tttggagcgt aataacctat ccgtcaagat ctttcggctg aataattcgg caaaaaaagt
      721 tctgctaagc aaaaagaaag tgagcgataa gtaagagttt gaatataggg agggataccc
      781 tatccgctat gaagaaaatg aggataatga tacttcttta gtgaaagccg gctcatctta
      841 acaggggcgg tggtgagatt ccaatgttgc tgatcctaag cacccgttaa tgtcatgaaa
      901 cttagttaga tgagaaagtt atagattgat tatataagag tttgaagaaa aaagggggga
      961 tgcatgtgga taatgactgg aatggactgg ctgagttgtt tgcgaatcta attacaaagt
     1021 atgctggtgt tttagatttg gataatctgc cagatccaac gccagcaaaa aatcaagaga
     1081 tgaaaaatag ttttgacatg gcaaaaacac aaattgagac ggactaataa aagtgttata
     1141 atatacttga aatgatagtc caaacttaaa ttaaaaaaat tatatatgat atagaaaaat
     1201 tatattgaga ttaatactat gtcaaaagaa aaaataaaag tatacctcta tacacgagta
     1261 tctacgtcaa tacagataga ggggtattcg ttagaggcac aaaaatcacg aatgaaagct
     1321 tttgctattt acaatgatta tgaaattgtt ggagagtatg aagatgccgg gaagtctggc
     1381 aagtctattg aaggtagaat acagttcaat cgaatgatgg aagatataaa atctggaaaa
     1441 gatggagtat cttttgttct tgtgtttaag ttatcaagat ttgcaagaaa tgccgctgat
     1501 gttctttcta cacttcagat aatgcaggat tatggagtta atcttatctg cgttgaagat
     1561 ggcattgatt catctaaaga tgctgggaaa ctaatgattt ctgttttatc agctgtggct
     1621 gaaatagaaa gagaaaacat ccgtattcaa acaatggaag atcgcattca aaaagcaagg
     1681 gaaggaaaat ggaatggtgg ctttgctccg tatggatata aacttgaaga cggcaagctg
     1741 tttataaatg aggaagaggc agttgcaata agaacgattt tcgaccagta tgtaaatact
     1801 acgataggag ccaatgggat atctaaatac ttagagaatc atggaattag aaaaatccca
     1861 agacagaatg gtaagaatcc tttgtttgat gcaggtctta taagaaagat attaaagaat
     1921 cctgtatata atgggaaaat agcatttgga agaagaactt tagaaaaagt tcatggtaca
     1981 agaaatgaat ataagcaggt tgaacaagat gaatatctaa tatctgaagg gatacatgaa
     2041 gctatagttt ccgatgaagt ttggcaagct gctcaggtta agctaaaatc tcaagcaaag
     2101 aaatatgagc atgtgaataa aggaaaagat acacgcacac acttgctttc tggaattgta
     2161 aaatgcccga tatgtggagt gggaatgttt gggaacaagt gtatcaagaa aaagaaagat
     2221 ggcacaaagt ataaagattt ttattactat ggttgtaaac ataggcagat gataagaggt
     2281 cataagtgta cattcagtaa gcaaattaga gaagaattgt tagatgatgc tgttgcagag
     2341 gtgattgtca agatagtaag taatccgaaa tttgcttcta tgatgcaaga aaaaatcaac
     2401 atgaaggtgg atacctctga aatagaaaaa gaaatagata attaccaaaa ggaattgaga
     2461 aagagtcatt ctacaaagtt taagctaatt gaggaaatag ataatttaga tgttgaagat
     2521 aagcactata agagaaggaa acaggattta gatgatagac tatatcgtat gtatgacaaa
     2581 atagatgaat tagaatcatc actaattgat gcgaaagcaa agaaacagac tattgaagct
     2641 gaaaaactta caggagataa catatataag gttctgatct attttgataa gctctataaa
     2701 gtcatgaatg atgtagagcg taggcagtta atttcagctt tgatttctga aattcaagtt
     2761 tatgaagaaa aacaatctaa cggacaatgg ctaaaatcca ttacttttaa actaccaatt
     2821 atagaagaaa atctcaacat aggtttggat aatgatgaac aagttgaatg tgtaagttta
     2881 ttagagaaac gtagttaatc ctcaaaaggt tccccaaacc ttttgagtcc cactgacgca
     2941 tcacgctgag gcggtatcac tgcttgtacg agttgaagca tcagcgaagt aaaagtagat
     3001 gttcagccaa tgcgacgagg tgagaccgaa ggtcgataag gtgtgttctg ggtataggac
     3061 tcgtaaagta agtaggaaat atgatgagat gatacagaga gcctgaattg gtcaggtgac
     3121 gtgcttattt acattagcct gataatgaaa atggagagat tatcgatggt tatattggaa
     3181 ttgtaccaaa atgattattc taaagattta gtagcatttg attccataga agatgggaaa
     3241 gcctttgtag ctcaaatccc gggatacact ctggaaacag aagatggttt tgaagtggag
     3301 tattttaatc ctaaaaacat accggattat atggaaatta tttttaacgg aaatattgtt
     3361 cctttatcta aatttatgtt cgatcctgag gaaaatgtaa acattatttg gaaagagatt
     3421 tcaaatttat ccctcaaaaa tgatagagtg atcgaaggat attcaaaaat tgatgcatat
     3481 gtcgttaaca accatgaagt taaagcctat gtcgaaacaa gagaaacgaa ctatcgtaaa
     3541 gcaaaagact tcttagaaag ccgcggatat gaaatcgaca gaagcttttt cggaagtgaa
     3601 gacggtgaag cgattcttta cagaaaaaaa gggatcgaag tttggcattt cttgtgtcac
     3661 ttagacccaa tgtttgtaga gattgaagat gtagaaggat atgttaaaga agaagttgga
     3721 gagattcaat agtcaaccaa agttccttgt gagtatatac ctttgctagt aaaagagtca
     3781 aaacgttata acgaaggggg gaagaaaacc cttgagtgta agtctttttc ttgtttagag
     3841 ggaaagtatt agagtagccg ctcataattt atactagatt tgataactga tttgagacag
     3901 attttatttc tataaatatt gtgaaaattt tttaatacca aagatttaaa gttactgtgt
     3961 taaaaatcct ctccactttt aaactaatgt attataaaag ccagttgaca caagtgttac
     4021 acctgtgata gaattaactt gaggtgatga aaatggcaac cgataaaaat agaataatga
     4081 ttagcttgga tgataaaaat ctagagaaac ttgaaaattt agtagaagat gctagagata
     4141 gaaggggaat gcgactaaca aagtcccagg ttattgaatt actcctaaat accgttgatt
     4201 atttcgatga tattatgggg gctatttact caaaaaaata agagcaaaat tgctattatt
     4261 ttttacaaat tggtgtaaca ctagtgatat aggagtgatg aaatggttgt ttatattaga
     4321 caaagtaaat taccaagtga ggtttcaatt aataaataca atgctcaagt aggtgcctac
     4381 ttacaaggag aagaagctgt tttatatcaa tctttttctg aaataaaaga gttaacaagt
     4441 gaagatatag ttgtagatta tataatggag actagagcat tactaaaaat gatgggctta
     4501 aacgttccgg ttcatgacta tcctattgag cttaaagagt tttatggtcg aaagatttat
     4561 gctggtattt taggagagat tgtgaatata cctgataatt ggggaaaatt tattaagcct
     4621 aaagctggtt caaaagtctt tactggaaga gttgttaatg gaacccatga tttaataggt
     4681 attggtctac ctttcgacta tcctatatgg attagtgagg ttgtagaatt catagctgaa
     4741 tggcgttgtt ttgtgttaga tggtcgcgta ttagatgttc gaccctatac aggtgattat
     4801 catgcacaat ttgatgcaag tgtaattgat gaagcgatat catgttggaa agatgcgcca
     4861 atagcttatg gactagatat cggtgttact cgcgatggca gaacacttgt tgttgaagta
     4921 aatgatggtt atgcattggg aaattatggc ctatctcctt taaaatcaat caattttcat
     4981 agagctaggt ggaaagaaat ggtaaaaccc tattttgaaa aaaatgaaat ttttaaaatc
     5041 caacaggatg ttgttttcta aaataaatat ggtatataac caatataaaa agcatcaaaa
     5101 tgaacaagga ggaatctgat gcttggagca attattggag atattgtcgg ttctgtttac
     5161 gaatggaaca atatcaaaac aaaggacttt cctttatttc ggaaggactg cttttttaca
     5221 gatgacacgg ttatgacctg tgctgttgca gaagcaatta tgaatggtgg acaaaaagac
     5281 gatttcattg acgcgatgaa gaaatatggc agaatgtatc cgaatgctga ttacggtgct
     5341 cggtttaatg catggctaaa cagcgataac cgtgagcctt ataatagctt tgggaatgga
     5401 tcagctatgc gtatttctcc atgtgcttgg atcatggact gtggttttta tgcgaaaact
     5461 ggtatgtggc catcatctag aggacttacg agtctttctg cagaggtaac tcataatcat
     5521 ccagaaggtg tcaaaggcgc tatggctaca gctgatgcta tctttctatg tcgtttttac
     5581 tttggtggtt attgtagaga gtacgagcaa tcaattaacg acaatcctac agagtgtaaa
     5641 agacgaatta aggattatat agaaaaagaa tacgattaca atctatctca aactttagat
     5701 gaaatccgtc ctaactatcg ttttaacgaa acatgtcagg aaactgtccc tcaagccatt
     5761 atcgcctttc ttgaaagtag agacttcgaa gatgcgataa gaaatgccat ctcacttggt
     5821 ggcgacagtg atactctcgc agcaatcact tgtagcatag cagaggcagc ttacggtatt
     5881 cctgattgga tcaaggataa ggcctattct tacttggatg aacccttaaa ggatgtagtt
     5941 aggcgatggg aaaatagaat aaaagcgtat taatctccag tacgtcagat ttctcttttc
     6001 tgtattttca ttgtataata ggattacatt tacttgcata cgacgaaatg taaacatttc
     6061 tgtttaaaat taaggataaa atcaatgaaa aaagcaatgg taattatcaa ccctacttct
     6121 ggtggcgaga aggctttgga ttacaaagaa aagctggaga ataaagcaaa agaatacttt
     6181 gaatatgttg aaaccaaaat taccgaaaaa gcgctggatg caacacattt tgctgaagaa
     6241 gcttctcgtg agcagtatga tgcagtggtt gtgtttggtg gagatggaac tgtcaatgaa
     6301 gtcatttcag gtattgatga gagagactac attcctaagt tagggattat cccaggcggt
     6361 acgggtaacc tcattacaaa acttttggaa atcaatcaag acatcgatgg cgcaattgac
     6421 gaactggatt ttgatttaac caataagatt gatatcggta aagcaaatga caactatttt
     6481 ggttatatct ttagtatcgg ttctctgcct gaggcgattc acaatgttga aatagaggac
     6541 aaaacaaaat tcggtatttt aacctatgct gtaaatacca tgaagtctgt catgacagat
     6601 caggtcttta acattaaggt tgagacagaa aatggaaatt atgttggtga agctagccat
     6661 gttttggtcc ttttgacaaa ttacttcgct gataagaaaa tctttgaaga aaacaaggac
     6721 ggctatgcca acattttgat tctgaaagat gcctctatat tctccaaatt atccgtcatt
     6781 cctgatttat taaaagggga tgttgtcgca aatgataata tcgagtatat caaagcgcgt
     6841 aatattaaaa tctcttcaga tagtgaattg gagtcagatg ttgacggaga taaatcagat
     6901 aacctacctg tagaaatcaa agtcctagct cagcgagtag aagtattttc aaaaccgaaa
     6961 gaggattagt atatagagaa agcctttttt aaggcttttt gtatacttta aaagatagtt
     7021 cctttaacaa cggacattcc ttgcaaatag ttcacaaaaa tagtatactg gatttattga
     7081 gtttgaaaac gtttgcgtaa aatttgaatg aatactttag gagacaaatt gatggaattg
     7141 agtgctattt accataggcc tgagtcggag tatgcctatc tttataagga taagaaactc
     7201 catattcgaa ttcgaactaa gaaaggggac attgaaagca tcaacttgca ctatggggac
     7261 ccttttatct ttatggagga gttttatcag gatacaaaag aaatggtcaa gataacttct
     7321 ggtaccttat ttgaccattg gcaggttgaa gtgtcagttg actttgcacg tatccagtat
     7381 ctctttgagc tcagagatac agaaggtcaa aatattttgt atggcgataa agggtgtgtg
     7441 gaaaattctc tagaaaatct tcatgcaatt gggaatggat ttaagttgcc ttatcttcat
     7501 gagattgatg cctgcaagat tcctgactgg gtttcaaata cggtatggta tcagatattt
     7561 cctgaaagat ttgccaatgg caatgctcta ttaaacccag aagggacttt agactgggat
     7621 tcatctgtca cacctaagag cgatgatttc tttggtggtg atttacaggg gattattgat
     7681 catatggatt acttgcaaga cttgggtatt actggactat atctttgtcc catctttgaa
     7741 tctacaagca atcacaagta caatacgaca gattactttg aaattgaccg tcattttgga
     7801 gacaaggaga cctttcggga actggtggat caagcgcatc atcgtggcat gaaagtcatg
     7861 ctggatgcgg tatttaatca tattggttcg caatctcttc aatggaaaaa tgtcgtcaaa
     7921 aatggtgaac agtctgctta taaggattgg ttccatattc aacaattccc agtgacaact
     7981 gaaaagctag ttaataagag agacttaccc tatcatgttt ttggtttcga ggactatatg
     8041 cctaagctaa atacagccaa tccagaggtc aagaattatc ttttaaaggt tgcgacttat
     8101 tggattgaag agtttaatat cgatgcttgg cgtttggatg tggctaatga gattgaccat
     8161 cagttctgga aggattttcg taaggcagtt ttagctaaaa atcctgatct ttatatccta
     8221 ggagaagtct ggcatacatc tcagccttgg ctaaatggag atgagttcca tgccgtcatg
     8281 aattatcctt tatctgatag tatcaaggac tatttcttac gaggaattaa gaagacagac
     8341 cagttcatcg atgaaatcaa tggagagtct atgtattaca agcagcagat ttcagaggtc
     8401 atgtttaatc tcttggattc acatgataca gagcgaatcc tgtggacggc caatgaagat
     8461 gttcaactgg ttaaatcagc cttagccttt ctctttttac aaaaaggaac accgtgcatt
     8521 tattacggaa ccgagttagc cttgactgga ggaccagatc cagattgtcg tcgttgtatg
     8581 ccttgggaac gtgtatcaag tgacaatgat atgctgaact ttatgaagag gctgattaag
     8641 attcggaaat acgcgtcagt aatcatttcg catggcaagt atagccttca agaaatcaaa
     8701 tctgatctag tagctctgga atggaaatac gaaggacgga tcctcaaagc aatattcaac
     8761 caatcaacag aagattatct tttagagaaa gaagcagtag cactagcaag caattgccaa
     8821 gaattggaga atcagcttgt catctctcca gatggatttg tgattttcta aaaactagtt
     8881 gatgaagatt atggtacatt tcatatctta tatagtataa taaggctagt tactaaactt
     8941 gtaaaggaga acttaaatga attgtagagg acatgaaaca agacaaagaa ttgttagaga
     9001 ttttgaagtt tagcctaaag cacatattaa gctgttagca aatcaacaaa aacatagtga
     9061 tgcaggagca actattgaag atgaatatta tgtatttatc gctgagagta aaattgatga
     9121 caagaaggaa gttattcagt gttgcatggg tgcggcaagg gattttttag aactaattaa
     9181 tcacaaaggg ctacctcttt ttaatccgct tgtaggtgat tctcatgtaa ataatagaca
     9241 agaatatgac aatacaggga gtggaaattt acaacctgaa aagtggaatg aaactgcaaa
     9301 gcagctttat aatgctataa tgtggttgat tattttatgg aatgctaagc cggatacacc
     9361 tttatttaat tttaaagacg aagtaattaa gtataaaaca tatgagcctt ttgaaagcag
     9421 tataaaattg gtatcaatca atgagtaaca aagtatcagc atgattcgaa acatttactt
     9481 gtaatttgcg gaggaacatc aatatggatg gaataacaaa agattttata aaaacggcta
     9541 aactaatgaa acaattatgg ccccaattga ccgataaaga agctattgat gaagtaaaaa
     9601 atatacgaat ggcaaaaata ctgcaatctt tactgaagtt gaaggtgaca caattgtagg
     9661 tctagcacta tgttcactca gatttgatta tgttgaaggt tgtaaatata gtcctgttgg
     9721 attcttagaa gggattattg ttgacgagga atatcgttta aaggatattg ctaaaaatct
     9781 ctgtacaaaa tgtgaggaat gtgcgaaaaa taaaggatgt aaggaatttg caagtgactg
     9841 tactttaacg aatacggatt ctataagatt tcatctcaat attggatttc aggaggcaaa
     9901 tagaattatt cattttaaga aaaaattata atttagaaac gtgaataaac ttgtttaaac
     9961 tttatgtatc tttagaaagt gtgttaactt gaaagaacaa atttttttga tgggtgggaa
    10021 tcccccaatg aagaaatata gtattgttga taaaattgta ttatcaacca agattaaaag
    10081 aattatcatt tttacagttt ttcgagaaaa ttgggaaccg tacatgaaaa agtacacgga
    10141 agtttttcaa agtcaatttc ctaatctaaa cattgattac ttgctcctgg acactgagca
    10201 gattgatctt gatagctatc tagatgctga cataattatc atcggtggtg gaaatacgga
    10261 aaaatatatt gctacttatg ttaatcagga gttcaaaagt tatatcgatc atatgcttaa
    10321 taaagaggca aaaattatag gattttctgc aggagcccta ctattaggag aaaaagtcta
    10381 tgtctcacct aatgataatt cagatcatca gataaagata aaaaatggat taggactctt
    10441 tagtcagttt ttaattagtg tccattatga ttcctggaat gataaagcaa ataaggatag
    10501 agctgaagaa ctcgttaatg ttcccataat tccactaaat gatcattctt gtcttgtatt
    10561 ggataaactt ggaaacatca tagagaaaat tgactaactt tcataatgta aaaatggatc
    10621 taggaaataa aagtgtagac gaactggata ggttactagt gaaaactgca aaaagtgttg
    10681 taaagtgaat cggagtgtgc ttgatggatt ttagtagtaa gatagccata aataaaggct
    10741 ggtcagatga taaaaaatat tgtgtgacag atcaaaatca gtaaaaatat ttcttgcgtg
    10801 tttctgataa gtcgaagtta gattataaaa aaatttgaat ttgatatgat ggagaaagta
    10861 gcttctcttg gagttccgat gtgtaaacca attagcattg aactctgcga tgacgaagta
    10921 cattctttac acgaatggat agacggaaga gatgcaatag atagcatttt agcttattca
    10981 gaaaaccaac aatacacata tggtgtagaa gcaggaaaga tacaaagata cttagaaaga
    11041 ttcatacaat tcctgctaca gaagtttgtg aagattggga aatttttttt aatctaaaaa
    11101 ttgatgataa aatctccaac gaaatgatat ggtaagtccg aaacgctcag tgtgtaagct
    11161 tgttgctaaa agcgtaaaaa ccttggaacg aaaggaataa tagacttcct gcgaaacaaa
    11221 aatacaatac aataaaacta tggatgatga agcaagtaaa caattaagcg atagccgttt
    11281 caagatcctt gtaggtgttc agcgcacgac ttttgaagag atgttagctg tgttaaaaac
    11341 agcttatcaa cgtaaacgcg caaaaggtgg acgaaaaagc aaattaagcc tagacgatct
    11401 ccttatggta actattcaat acatgcgaga atagagcact tatgaacaaa ttgcggctga
    11461 ttttggcatt cacgaaagca acttaattcg tcggagtcaa tgggttgaag caactcttat
    11521 tcaaaatggt tttacgattt caaattctgc cttaattctg taaaaacagt aaaattcgaa
    11581 ggattgtaag gtaagagttt ttttctttct gaaaaaatgg tataatagca atcaaaacta
    11641 gaaaataaaa cggaatttgg aacagatttg tctgtatcct agtagagtgg tgatactatg
    11701 aagattagta agaggcactt attaaattat tccatcttga ttccctactt gcttttatct
    11761 attttgggct tgattgtggt ctattcgacc accagtgcta ttttaattga agaaggcaag
    11821 agcgccttgc agttggttcg aaaccaagga atcttttgga ttgttagttt gatactgatt
    11881 gccttaattt ataaattgag actagatttt ttgagaaatg agcgactaat cattttagtt
    11941 atattaatag aaatgctttt attgttcttg gctcgtttta ttggtatttc agtaaacggg
    12001 gcatacggtt ggatttcggt tgcaggagta actattcagc cagctgagta cttaaaaatc
    12061 attattattt ggtatttagc tcaccgattc tccaaacagc aagaagaaat agctacttat
    12121 gattttcaag ttttgactca aaatcaatgg cttccccgtg cttttaatga ttggcgattc
    12181 gttctcctag ttctgattgg aagtttggga attttccctg atttaggaaa tgcgactatt
    12241 ttagtcttgg tttccttgat tatgtataca gttagtggaa tcgcttatcg ctggttttca
    12301 accattctgg cgctcgtatc tgccacttct gtctttgtct tgaccactat cagcctaatc
    12361 ggtgttgaga ccttttcaaa aattccagta tttggctatg tagccaagcg ctttagtgcc
    12421 ttttttaatc cttttgccga tcgtgctgat gcaggtcacc agttagctaa ttcttatttt
    12481 gccatggtca atggtggttg gtttggtcta ggtcttggaa actcgattga aaaacgaggt
    12541 tatttgccag aagctcatac agactttgtc ttttctatcg tgattgaaga atttggcttt
    12601 gttggtgcca gtcttatttt agctctcttg tttttcatga ttttgcggat tatcttggtc
    12661 ggtatccgag cggagaatcc tttcaatgcc atggttgcac tcggtgtcgg agggatgatg
    12721 ttggttcagg tatttgtcaa tatcggaggg atttcgggct tgattccatc tacaggagtg
    12781 actttccctt tcttatccca gggtggaaat agtcttctag tcttatcagt ggcagtagcc
    12841 tttgtcttaa atattgatgc cagtgaaaaa cgcgctaagt tgtaccgaga attggaaaat
    12901 caaccaatga accttctgtt gaagtaggat aaagaaagga tagtttatgt ctcttcaaaa
    12961 attagaaaat tatagtaata aaagtgttgt gcaagaagaa gtcttgattc taacagaatt
    13021 actggaagat attactaaaa atatgcttgc cccagagacc tttgaaaaaa taatacagtt
    13081 gaaagaatta tcaacgcagg aagattatca aggtctaaac cgtctagtga ctagcttatc
    13141 aaatgatgaa atggtctata tttcacgcta tttctctatc ttgcctcttt tgattaatat
    13201 ttcagaggat gtggatttag cttatgaaat caatcatcaa aataatattg atcaggacta
    13261 tttaggtaaa ttatctacaa cgattaaatt ggtagcagaa aaggaaaatg ccgttgagat
    13321 cctagaacac ttgaatgttg tccctgtttt gacagcccat ccaacacaag tgcaacgcaa
    13381 aagtatgttg gatttaacaa atcatattca tagtcttttg cgtaaatacc gtgatgttaa
    13441 gttggggttg atcaataaag ataaatggta caatgatttg cgtcgttaca tcgaaattat
    13501 catgcagaca gacatgattc gtgagaaaaa attaaaagtg actaacgaaa tcacgaatgc
    13561 tatggaatat tataacagct cctttttgaa agctgtacct catttgacga cggagtataa
    13621 gcgcttagcg caagcgcatg gtctgaattt aaaacaggct aaaccaatca ccatgggtat
    13681 gtggataggt ggtgaccgtg atggaaatcc atttgttaca gcaaagacct tgaagcagtc
    13741 tgcactcact cagtgtgaag tcatcatgaa ctactatgat aaaaagattt accaacttta
    13801 tcgtgaattt tctctttcaa ctagcattgt caacgtcagc aagcaagtca gagaaatggc
    13861 tcgtcaatcc aaggataact cgatttaccg cgaaaaagag ctttaccgtc gtgccttgtt
    13921 tgatattcaa tcaaaaattc aggcaactaa aacctatctg attgaggata aagaagttgg
    13981 gactcgttat gaaaccgcca atgatttcta caaggatttg attgccattc gagattctct
    14041 actagaaaat aagggcgagt ccttgatttc aggtgatttt gtggaattat tgcaggcagt
    14101 agagatattt ggtttttact tagcatcaat tgatatgcga caagactcta gcgtctatga
    14161 agcctgtgtg gcagaactct tgaaatcagc aggaattcat tctcgttata gcgagttgag
    14221 cgaagaagaa aagtgtgacc ttctcttgaa agaattagaa gaagatcccc gaattctttc
    14281 tgcgactcac gcagaaaaat cagaattatt agcaaaagaa ttagctattt ttaagacggc
    14341 tcgtgttttg aaagataagt tgggagatga tgtcatccgt cagaccatca tttcacatgc
    14401 aaccagcctt tctgatatgc tagaattagc tattctgtta aaagaagtag gactggtgga
    14461 tacggaaagg gcgcgtgttc agattgttcc cctttttgaa acaattgaag acttggatca
    14521 ttcagaggaa acaatgagaa aatatctttc tcttagcctt gccaaaaaat ggattgactc
    14581 acgaaataac taccaagaaa tcatgcttgg ctactctgac agtaataaag atggcggtta
    14641 cttgtcatca tgttggaccc tctacaaggc tcaacaacaa ttgactgcta ttggagatga
    14701 atttggcgtt aaggttacct tcttccatgg tcgtggtggt actgtcggtc gtggtggtgg
    14761 gccaacctat gaagccatta cgtctcaacc gctcaagtct atcaaggatc gtatccgctt
    14821 gacggagcag ggtgaagtaa ttgggaataa atacggtaac aaagacgccg cttactataa
    14881 ccttg
//
